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IHARA Makoto
井原 誠
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Alternative Names
井原 誠 イハラ マコト
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Researcher Number
60175213
External Links
Affiliation (Current)
2023: 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員
Affiliation (based on the past Project Information)
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2022: 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員
2013 – 2016: 長崎大学, 原爆後障害医療研究所, 助教
2012: 長崎大学, 医歯(薬)学総合研究科, 助教
2009: 長崎大学, 医歯薬学総合研究科, 助教
2006: Nagasaki University, Graduate School of Biomedical Sciences, Assistant Professor, 大学院医歯薬学総合研究科, 助手
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2003 – 2005: Nagasaki University, Graduated School of Biochemical Sciences, Assistant Professor, 大学院・医歯薬学総合研究科, 助手
1995 – 2002: 長崎大学, 医学部, 助手
1988: 奈良医科大学, 研究員
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Review Section/Research Field
Principal Investigator
Radiation science
Except Principal Investigator
Risk sciences of radiation/Chemicals
/
Radiation science
/
Radiation science
/
環境影響評価(含放射線生物学)
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Medium-sized Section 63:Environmental analyses and evaluation and related fields
Keywords
Principal Investigator
DNA-PK / Ku70 / 80 / 温熱処理 / 熱ショック蛋白質 / Ku80 / HSC73 / DNA二本鎖切断 / DNA-PK活性 / DNA二本鎖切断の修復
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/ X線 / DNA double strand break / Heat treatment / 熱失活の回復 / Heat shock protein / Recovery of hea-inactivation / Heat shock Protein
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More
Except Principal Investigator
p53 / 放射線感受性 / 変異部位 / RBE / 癌治療 / 放射線耐性 / 放射線治療 / アポトーシス / Saos-2 / 突然変異 / scid細胞 / 重粒子線 / DNA二重鎖切断 / DNA-PK活性 / heavy ion particles / radiosensitivity / DNA double strand breaks / DNA-PK activity / scid cells / FAK / ERK / ATM / MTF-1 / DNA-PK / XRCC / 損傷乗り越え複製 / 紫外線 / Polymerase I / 光回復 / 除去修復 / 修復間違い / メチルメタンスルフォン酸 / 内部被ばく / 放射性ヨウ素 / 分子イメージング / 福島原発事故 / リスクコミュニケーション / 核医学 / 膵癌 / テーラーメイド医療 / FDG PET / 腫瘍浸潤 / 光回復酵素 / シクロブタン型ピリミジン二量体 / 光吸収体 / 部位特異的突然変異誘発 / 活性中心 / 癌遺伝子 / 熱感受性 / NIH3T3細胞 / Oncogene / Thermosensitivity / NIH3T3 Cells / DNAニ重鎖切断 / シグナルトランスダクション / 遺伝子導入 / Saos2 / シグナル伝達 / G1停止 / SaOS-2 / mutation / radio-sensitivity / signal transduction / apoptosis / transduction / DNA二重鎖 / 細胞運動性 / がん転移 / X線 / インテグリン / ラミニン / 癌転移 / 細胞外マトリックス / 放射線照射 / 神経膠芽腫細胞 / P53 / cell mobility / metastasis / X-ray / integrin / laminin / 甲状腺 / 放射線 / DNA修復 / 細胞周期 / MDM2 / 甲状腺がん / thyroid / radiation / DNA repair / cell cycle / DNA修復モデル / 放射線突然変異 / 放射線リスク / 非相同末端再結合 / 相同組換え修復
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Research Projects
(
16
results)
Research Products
(
2
results)
Co-Researchers
(
18
People)
Project Start Year (Newest)
Project Start Year (Oldest)
DNA修復細胞集団の再構成に伴う低線量放射線リスクの上振れ
Principal Investigator
小松 賢志
Project Period (FY)
2022 – 2024
Research Category
Grant-in-Aid for Challenging Research (Exploratory)
Review Section
Medium-sized Section 63:Environmental analyses and evaluation and related fields
Research Institution
Kyoto University
Development of patient specific medicine using FDG PET and gene expression
Principal Investigator
KUDO Takashi
Project Period (FY)
2014 – 2016
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Radiation science
Research Institution
Nagasaki University
Evaluation of health risk of internal exposure with radioactive iodine by molecular imaging
Principal Investigator
MATSUDA Naoki
Project Period (FY)
2012 – 2015
Research Category
Grant-in-Aid for Challenging Exploratory Research
Research Field
Risk sciences of radiation/Chemicals
Research Institution
Nagasaki University
紫外線誘発突然変異は除去修復ギャップの修復複製で生じる
Principal Investigator
山本 和生
Project Period (FY)
2009
Research Category
Grant-in-Aid for Challenging Exploratory Research
Research Field
Risk sciences of radiation/Chemicals
Research Institution
Tohoku University
Study of Involvement of DNA Repair in Radiation Induced Thyroid Cancer
Principal Investigator
ASHIZAWA Kiyoto
Project Period (FY)
2004 – 2006
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Risk sciences of radiation/Chemicals
Research Institution
Radiation Effects Research Foundation
Effect of X-ray irradiation on tumor metastasis
Principal Investigator
MATSUDA Naoki
,
奥村 寛
Project Period (FY)
2003 – 2006
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Radiation science
Research Institution
Nagasaki University
Role of heat shock protein (HSP) for the recovery of heat-inactivated DNA-PK
Principal Investigator
Principal Investigator
MAKOTO Ihara
Project Period (FY)
2001 – 2003
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Radiation science
Research Institution
Nagasaki University
Radiosensitivity of Scid Cells Deficient in Repair of DNA Damages Induced by High LET Irradiation
Principal Investigator
OKUMURA Yutaka
Project Period (FY)
2000 – 2002
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Radiation science
Research Institution
Nagasaki University
p53の変異部位に対応した放射線による癌治療法の開発
Principal Investigator
岡市 協生
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Nagasaki University
p53の変異部位に対応した放射線による癌治療法の開発
Principal Investigator
岡市 協生
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Nagasaki University
Relationship between DNA double strand break repair and DNA-PK activity
Principal Investigator
Principal Investigator
IHARA Makoto
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Radiation science
Research Institution
Nagasaki University
p53の変異部位に対応した放射線による癌治療法の開発
Principal Investigator
OKAICHI Kumio
Project Period (FY)
1997
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Nagasaki University
Radiosensitivity of scid cells for heavy ion particles
Principal Investigator
OKUMURA Yutaka
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Radiation science
Research Institution
NAGASAKI UNIVERSITY
The changes of radio-sensitivity and signal transduction by mutation in p53
Principal Investigator
OKAICHI Kumio
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
環境影響評価(含放射線生物学)
Research Institution
Nagasaki University
Analysis of Thermotolerance of Cancer by Introduction of Oncogeges
Principal Investigator
OKUMURA Yutaka
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Radiation science
Research Institution
Nagasaki University
大腸菌光回復酵素遺伝子の構造と酵素の機能
Principal Investigator
山本 和生
Project Period (FY)
1988
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka Prefectural Institute of Public Health
All
2016
2015
All
Presentation
[Presentation] DNA二重鎖切断修復過程に働くATMの線量依存性
2016
Author(s)
井原誠, 斉藤裕一郎, 小林純也, 栗政明弘, 工藤崇
Organizer
日本放射線影響学会第59回大会
Place of Presentation
JMSアステールプラザ（広島県・広島市）
Year and Date
2016-10-26
Data Source
KAKENHI-PROJECT-26461857
[Presentation] Association of ATM with the rejoining of DNA double-strand breaks in cells lacking non-homologous end-joining
2015
Author(s)
Makoto Ihara
Organizer
15th International Congress of Radiation Research
Place of Presentation
京都国際会議場（京都府・京都市）
Year and Date
2015-05-25
Int'l Joint Research
Data Source
KAKENHI-PROJECT-26461857
# of Projects (Dsc)
# of Projects (Asc)
1.
OKUMURA Yutaka
(00073130)
# of Collaborated Projects:
10 results
# of Collaborated Products:
0 results
2.
OKAICHI Kumio
(80124874)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
3.
MATSUDA Naoki
(00304973)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
KUDO Takashi
(20330300)
# of Collaborated Projects:
2 results
# of Collaborated Products:
1 results
5.
山本 和生
(20093536)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
NAKAYAMA Morio
(60164373)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
SIMASAKI Tatsuya
(60264248)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
TAKESHITA Satoshi
(20295083)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
MORITA Naoko
(90380972)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
ASHIZAWA Kiyoto
(10304932)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
NANBA Hiroyuki
(80237635)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
吉田 正博
(50264247)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
福岡 順也
(00324575)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
上谷 雅孝
(40176582)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
七島 篤志
(60380838)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
山下 俊一
(30200679)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
小松 賢志
(80124577)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
田内 広
(70216597)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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