OGAWA Yasuhiro 小川恭弘

… Alternative Names

Researcher Number	90152397
Other IDs
External Links
Affiliation *help	2016 – 2018 : 高知大学, その他部局等, 名誉教授 2015 : 高知大学, その他の部局等, 名誉教授 2014 – 2015 : 高知大学, 学内共同利用施設等, 名誉教授 2013 : 高知大学, 教育研究部医療学系, 准教授 2011 – 2013 : 高知大学, 教育研究部医療学系, 教授 … More
Review Section/Research Field	Principal Investigator Radiation science / Radiation science / Biological Sciences Except Principal Investigator Radiation science / Digestive surgery / Gastroenterology / Radiation science
Keywords	Principal Investigator アポトーシス / 放射線治療 / 放射線増感剤 / ミトコンドリア / リソソーム / 過酸化水素 / リンパ球 / Tリンパ球 / KORTUC / lysosome … More Except Principal Investigator 放射線感受性 / 先行指標 / 分割照射 / 低酸素性細胞 / 放射線誘導タンパク / p53 / 放射線抵抗性の誘導 / マウス移植腫瘍 / BRM / RALS / KIN806 / 放射線増感剤 / Micronucleus Assay / 細胞死(アポトーシス) / HPV / リン酸化・脱リン酸化 / 放射線治療 / Micronucleus assay / リンパ球浸潤 / 色素排除試験 / KIN896 / 脂肪肝炎 / DNA・PK / 放射線効果増強 / KIN804 / FERRITIN / Human Papillomavirus / Low dose Survival Curve / Metastasis / 拡散強調画像 / Radiosensitizer / 脂肪肝 / Ataxia telangiectasia遺伝子 / KIN844 / cyp19 / 治療効果予測 / estrogen / 生物学的応答修飾物質 / DNA依存性プロテインキナーゼ / 高線量率腔内照射 / DNA-PK / 転移 / アポトーシス / 単クローン抗体 Ki67・PCNA / High-Dose-Rate Intracavitary Irradiation / 免疫賦活作用 / PLATELET / Esophageal Cancer / STEATOHEPATITIS / ヒトパピローマウイルス / 治療効果 / 感受性修飾 / AGE / ArKO / Radiotherapy / インスリン抵抗性 / COMPUTED TOMOGRAPHY / BRM併用放射線治療 / MRI / 乳癌 / 化学療法 / NASH / がん転移抑制 / 先行指導 / 腫瘍浸潤単核球 / 食道癌 / aromatase / Ki,BUdR Indeces / 癌関連遺伝子単クローン抗体 / NBS1 / 奇形 / p53欠失マウス / 温熱による放射線の増感 / ヒトパピローマウィルス / 抗癌剤 / がん転移 / ナイミ-ヘン症候群 Less

Development of a novel enzyme-targeting radiosensitizer (New KORTUC) using a gelatin-based hydrogel instead of a siduim hyaluronatePrincipal Investigator
- Principal Investigator
  
  OGAWA YASUHIRO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kochi University
Early prediction of response to neoadjuvant chemotherapy in patients with breast cancer using diffusion-weighted imaging
- Principal Investigator
  
  KUBOTA KEI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kochi University
Identification of the therapeutic effect of new enzyme-targeting radiosensitization treatment, KORTUC for tumor stem cellsPrincipal Investigator
- Principal Investigator
  
  OGAWA Yasuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kochi University
Identification of a new apoptotic pathway of radiation-induced apoptosis of human peripheral lymphocytesPrincipal Investigator
- Principal Investigator
  
  OGAWA Yasuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kochi University
Reactive oxygen species producing site in radiation-induced apoptosis of human peripheral T cells: Involvement of lysosomal membrane destabilizationPrincipal Investigator
- Principal Investigator
  
  OGAWA Yasuhiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  KOCHI UNIVERSITY
  高知大学(医学部)
癌の放射線・化学療法におけるG-CSF使用後の増加顆粒球の早期減少メカニズムPrincipal Investigator
- Principal Investigator
  
  小川恭弘
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  高知医科大学
Development of noninvasive procedure for diagnosis of NASH and of therapeutic strategy
- Principal Investigator
  
  SAIBARA Toshiji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kochi medical School
Mechanism of radiation-induced apoptosis of human peripheral T cellsPrincipal Investigator
- Principal Investigator
  
  OGAWA Yasuhiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kochi Medical School
放射線感受性予測の基礎研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
放射線感受性予測の基礎研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
マウス移植腫瘍に対する放射線照射による癌関連遺伝子発現とアポトーシスの経時的変化Principal Investigator
- Principal Investigator
  
  小川恭弘
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  高知医科大学
The immunopotentiation effects of low neurotoxic radiosensitizers KIN806 and KIN896
- Principal Investigator
  
  INOMATA Taisuke
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kochi Medical School
腫瘍の放射線分割照射に関する基礎研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
腫瘍の放射線分割照射に関する基礎研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Immunohistochemical study of expression of several proto-oncogenes in cancer tissues from patients undergoing radiation therapyPrincipal Investigator
- Principal Investigator
  
  OGAWA Yasuhiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kochi Medical School
腫瘍の放射線分割照射に関する基礎研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
がん治療における放射線の時間的線量配分に関する研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
High-Dose-Rate Intracacvitary Irradiation in the Surgical Treatment of Cancer of the Tracic Esophagus
- Principal Investigator
  
  OGOSHI Shohei
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kochi Medical School
がん治療における放射線の時間的線量配分に関する基礎研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
放射線と生物学的応答修飾物質,増感剤との相互作用及び放射線効果増強に関する研究
- Principal Investigator
  
  高橋正治
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Development and clinical application of a predictive assay for radiotherapy using an immunohistochemical methodPrincipal Investigator
- Principal Investigator
  
  OGAWA Yasuhiro
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kochi Medical School
がん治療における放射線の時間的線量配分に関する基礎研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo

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All Journal Article Presentation Book

[Book] 新しい酵素標的・増感放射線療法KORTUCの基礎と臨床2015
- Author(s)
  小川　恭弘
- Total Pages
  184
- Publisher
  篠原出版新社
- Data Source
  KAKENHI-PROJECT-25461916
[Book] 癌の臨床特集酵素標的・増感放射線療法KORTUCの基礎と臨床2011
- Author(s)
  小川恭弘, 他
- Publisher
  篠原出版新社
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] Serail assessment of therapeutic response to a new radiosensitization treatment, kochi Oxydol-radiation Therapy for Unresectable Carcinomas, Type II (KORTUC II), in patients with stage I/II breast cancer using breast contrast-enhanced magnetic resonance imaging2016
- Author(s)
  Yaogawa S, Ogawa Y, Morita-Tokuhiro S, Tsuzuki A, Akima R, Itoh K, Morio K, Yasunami H, Onogawa M, Kariya S, Nogami M, Nishioka A, Miyamura M
- Journal Title
  
  cancers
  
  Volume : 8 Pages : 1-11
- DOI
  10.3390/cancers8010001
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461916
[Journal Article] Raradigm shift in radiation biology/radiation oncology - Exploitation of the "H2O2 effect" for radiotherapy using low-LET (linear energy transfer) radiation such as x-rays and high-energy electrons2016
- Author(s)
  Ogawa Y
- Journal Title
  
  Cancers
  
  Volume : 8 Pages : 28-28
- DOI
  10.3390/cancers8030028
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461916
[Journal Article] Therapeutic response to a novel enzyme-targeting radiosensitization treatment (Kochi Oxydol-Radiation Therapy for Unresectable Carcinomas) in patients with recurrent breast cancer2016
- Author(s)
  Aoyama N, Ogawa Y, Yasuoka M, Takahashi M, Iwasa H, Miyatake K, Yamanishi T, Hamada N, Tamura T, Nishioka A, Yamagami T
- Journal Title
  
  Oncol Lett
  
  Volume : 11 Pages : 1-6
- DOI
  10.3892/ol.2016.4589
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461916, KAKENHI-PROJECT-16K10352
[Journal Article] Development of a novel enzyme-targeting radiosensitizer (New KORTUC) using a gelatin-based hydrogel instead of a sodium hyalutronate2016
- Author(s)
  Morita-Tokuhiro S, Ogawa Y, Yokota N, Tsuzuki A, Oda H, Ishida N, Aoyama N, Nishioka A
- Journal Title
  
  Cancers
  
  Volume : 8 Pages : 10-10
- DOI
  10.3390/cancers8010010
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461916
[Journal Article] Computed tomography demonstration of the production and distribution of oxygen gas following intratumoral injection of a new radiosensitizer (KORTUC) for patients with breast cancer - is intratumoral injection not an ideal approach to solve the major problem of tumor hypoxia in radiotherapy?2016
- Author(s)
  Hayashi N, Ogawa Y, Kubota K, Okino K, Akima R, Morita-Tokuhiro S, Tsuzuki A, Yaogawa S, Nishioka A, Miyamura M
- Journal Title
  
  Cancers
  
  Volume : 8 Pages : 43-43
- DOI
  10.3390/cancers8040043
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461916
[Journal Article] Non-surgical breast-conserving treatment (KORTUC-BCT) using a new radiosensitization method (KORTUC II) for patients with stage I or II breast cancer2015
- Author(s)
  Ogawa Y, Kubota K, Aoyama N, Yamanishi T, Kariya S, Hamada N, Nogami M, Nishioka A, Onogawa M, Miyamura M
- Journal Title
  
  Cancers
  
  Volume : 7 Pages : 2277-89
- DOI
  10.3390/cancers7040891
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461916
[Journal Article] 肝細胞癌の左鎖骨上かリンパ節転移2014
- Author(s)
  小川恭弘、山西伴明、青山信隆、野上宗伸、久保田　敬
- Journal Title
  
  臨床放射線
  
  Volume : 58 Pages : 885-888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461916
[Journal Article] Safety and efficacy of image-guided enzyme-targeting radiosensitization and intraoperative radiotherapy for locally advanced unresectable pancreatic cancer2014
- Author(s)
  Nishioka A, Ogawa Y, Miyatake K, Tadokoro M, Nogami M, Hamada N, Kubota K, Kariya S, Kohsaki T, Saibara T, Okabayashi T, Hanazaki K
- Journal Title
  
  Oncology Letters
  
  Volume : 8 Pages : 404-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461916
[Journal Article] Therapeutic response to a new enzyme-targeting radiosensitization treatment (KORTUC-SC) for patients with chemotherapy-resistant supraclavucular lymph node metastasis2013
- Author(s)
  Aoyama N, Ogawa Y, Kubota K, Ohgi K, Kataoka Y, Miyatake K, Tadokoro M, Yamanishi T, Ohnishi T, Hamada N, Kariya S, Tamura T, Nogami M, Nishioka A, Onogawa M, Miyamura M
- Journal Title
  
  Journal of Cancer Research & Therapy
  
  Volume : 1(9) Pages : 215-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461916
[Journal Article] Evaluation of changes in tumor shadows and microcalcification on2011
- Author(s)
  Tsuzuki A, Ogawa Y, et al
- Journal Title
  
  Cancers
  
  Volume : 3 Pages : 3496-3505
- DOI
  10.3390/cancers3033496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] Safety and effectiveness of a new enzyme-targeting radiosensitization2011
- Author(s)
  Ogawa Y, et al
- Journal Title
  
  Int J Oncol
  
  Volume : 39 Pages : 553-560
- DOI
  10.3892/ijo.2011.1069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] Safety and effectiveness of a new enzyme-targeting radiosensitization treatment(KORTUC II) for intratumoral injection for low-LET radioresistant tumors2011
- Author(s)
  Ogawa Y, Kubota K, Ue H, Tadokoro M, Matsui R, Yamanishi T, Hamada N, Kariya S, Nishioka A, Nakajima H, Tarutani M, Sano S
- Journal Title
  
  Int J Oncol
  
  Volume : 39 Pages : 553-560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] Evaluation of changes in tunor shadows and microcalcifications on mammography following KORTUC II, a new radiosensitization treatment without any surgical procedure for elderly patients with stage I and II breast cancer2011
- Author(s)
  Tsuzuki A, Ogawa Y, Kubota K, Tokuhiro S, Akima R, Yaogawa S, Itoh zk, Yamada Y, Sasaki T, Onogawa M, Yamanishi T, Kariya S, Nogami M, Nishioka A, Miyamura M
- Journal Title
  
  Cancers
  
  Volume : 3 Pages : 3496-3505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] Development of a new enzyme-targeting radiosensitizer(KORTUC) containing hydrogen peroxide for intratumoral injection for patients with low linear energy transfer(LET) radioresistant neoplasms2010
- Author(s)
  Tokuhiro S, Ogawa Y, Tsuzuki A, Akima R, Ue H, Kariya S, Nishioka A
- Journal Title
  
  Oncol Lett
  
  Volume : 1 Pages : 1025-1028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] Non-surgical therapy and radiologic assessment of stage I breast cancer treatment with novel enzyme-targeting radiosensitization : Kochi Oxydol-radiation therapy for unresectable carcinomas, type II(KORTUC II)2010
- Author(s)
  Hitomi J, Kubota K, Ogawa Y, Hamada N, Murata Y, Nishioka A
- Journal Title
  
  Exp Ther Med
  
  Volume : 1 Pages : 769-775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] Non-surgical therapy and radiologic assessment of stage I breast cancer treatment with novel enzyme-targeting radiosensitization, KORTUC II2010
- Author(s)
  Hitomi J, Kubota K, Ogawa Y, et al
- Journal Title
  
  Exp Ther Med
  
  Volume : 1 Pages : 769-775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] Development of a new enzyme-targeting radiosensitizer (KORTUC) containing hydrogen peroxide for intratumoral injection for patients……2010
- Author(s)
  Tokuhiro S, Ogawa Y, et al
- Journal Title
  
  Oncol Letters
  
  Volume : 1 Pages : 1025-1028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] Non-surgical care for locally advanced breast cancer : Radiologically assessed therapeutic outcome of a new enzyme-targeting radiosensitization…2010
- Author(s)
  Miyatake K, Kubota K, Ogawa Y, et al
- Journal Title
  
  Oncol Rep
  
  Volume : 24 Pages : 1161-1168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] Non-surgical care for locally advanced breast cancer : Radiologically assessed therapeutic outcome of a new enzyme-targeting radiosensitization treatment, Kochi Oxydol-radiation therapy for unresectable carcinomas, type II(KORTUC II) with systemic chemotherapy2010
- Author(s)
  Miyatake K, Kubota K, Ogawa Y, Hamada N, Murata Y, Nishioka A
- Journal Title
  
  Oncol Rep
  
  Volume : 34 Pages : 1161-1168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] 新しい酵素標的・増感放射線療法KORTUCの臨床応用の現状と将来展望2009
- Author(s)
  小川恭弘
- Journal Title
  
  臨祥放射線 54
  
  Pages : 1251-1263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] 新開発の放射線増感剤(過酸化水素含有ヒアルロン酸ナトリウム)による著明な臨床効果2009
- Author(s)
  小川恭弘
- Journal Title
  
  癌の臨床 55
  
  Pages : 255-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591610
[Journal Article] New radiosensitization treatment(KORTUC I)using hydrogen peroxide solution-soaked gauze bolus for unresectable and superficially exposed neoplasms2008
- Author(s)
  小川恭弘, ほか
- Journal Title
  
  Oncology Reports (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591382
[Journal Article] New radiosensitization treatment (KORTUC I) using hydrogen peroxide solution-soaked gauze bolus for unresectable and superficially exposed neoplasms2008
- Author(s)
  小川恭弘, ほか
- Journal Title
  
  Oncology Reports (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591382
[Journal Article] Sentinel node biopsy in breast cancer patients treated with neoadjuvant chemotherapy2006
- Author(s)
  Tanaka Y, Maeda H, Ogawa Y, Nishioka A, Itoh S, Kubota K, Ue H, et al.
- Journal Title
  
  Oncology Reports 15
  
  Pages : 927-931
- Data Source
  KAKENHI-PROJECT-18591382
[Journal Article] Diffuse micronodular pulmonary metastasis of lung adenocarcinoma predicts gefinitib response in association with epidermal.....2006
- Author(s)
  Kobayashi M, Takeuchi T, Bandobashi K, Uemura Y, Ogawa Y, et al.
- Journal Title
  
  Anticancer Research 26
  
  Pages : 1621-1626
- Data Source
  KAKENHI-PROJECT-18591382
[Journal Article] Umbilical metastasis from breast cancer related with tumor marker elevation2006
- Author(s)
  Murata Y, Ogawa Y, Yamawaki Y, Kohsaki S, Kubota K, et al.
- Journal Title
  
  Radiation Medicine 24
  
  Pages : 77-79
- Data Source
  KAKENHI-PROJECT-18591382
[Journal Article] Immunocytochemical characteristics of human osteosarcoma cell line HS-Os-1 : Possibel implication in apoptotic resistance.....2004
- Author(s)
  Ogawa Y., et al.
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages : 397-403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Prevention of hydrogen peroxide-induced apoptosis of human peripheral T cells by a lysosomotropic iron chelator, ammonium...2004
- Author(s)
  Ogawa Y., et al.
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages : 1007-1013
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Reactive oxygen species-producing site in radiation-induced apoptosis of human peripheral T cells : Involvement of lysosomal..2004
- Author(s)
  Ogawa Y., et al.
- Journal Title
  
  International Journal of Molecular Medicine 13
  
  Pages : 69-73
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Immunocytochemical characteristics of human osteosarcoma cell Line of HS-Os-1 : Possible implication in apoptotic resistance.2004
- Author(s)
  小川恭弘
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages : 397-403
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Reactive oxygen species-producing site in radiation-induced apoptosis of human peripheral T cells : Involvement of lysosomal.2004
- Author(s)
  小川恭弘
- Journal Title
  
  International Journal of Molecular Medicine 13
  
  Pages : 69-73
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Prevention of hydrogen peroxide-induced apoptosis of human peripheral T cells by a lysosomotropic iron chelator, ammonium.2004
- Author(s)
  小川恭弘
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages : 1007-1013
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Prevention of hydrogen peroxide-induced apoptosis of human peripheral T cells by a lysosomotropic iron chelator, ammonium..2004
- Author(s)
  小川恭弘
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages : 1007-1013
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Immunocytochemical characteristics of human osteosarcoma cell line HS-Os-1 : Possible implication in apoptotic resistance...2004
- Author(s)
  小川恭弘
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages : 397-403
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Reactive oxygen species-producing site in radiation-induced apoptosis of human peripheral T cells : Involvement of lysosomal..2004
- Author(s)
  小川恭弘
- Journal Title
  
  International Journal of Molecular Medicine 13
  
  Pages : 69-73
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Apoptotic-reisistance of the human osteosarcoma cell line HS-Os-1 to irradiation is converted to apoptotic-susceptibility by.....2003
- Author(s)
  Ogawa Y., et al.
- Journal Title
  
  International Journal of Molecular Medicine 12
  
  Pages : 845-850
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Mechanism of hydrogen peroxide-induced apoptosis of the human osteosarcoma cell line HS-Os-12003
- Author(s)
  Ogawa Y., et al.
- Journal Title
  
  International Journal of Molecular Medicine 12
  
  Pages : 459-463
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Mechanism of apoptotic-resistance of human osteosarcoma cell line HS-Os-1 against irradiation2003
- Author(s)
  Ogawa Y., et al.
- Journal Title
  
  International Journal of Molecular Medicine 12
  
  Pages : 453-458
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Apoptotic-resistance of the human osteosarcoma cell line HS-Os-1 to irradiation is converted to apoptotic-susceptibility by...2003
- Author(s)
  小川恭弘
- Journal Title
  
  International Journal of Molecular Medicine 12
  
  Pages : 845-850
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Mechanism of hydrogen peroxide-induced apoptosis of the human osteosarcoma cell line HS-Os-12003
- Author(s)
  小川恭弘
- Journal Title
  
  International Journal of Molecular Medicine 12
  
  Pages : 459-463
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Journal Article] Mechanism of apoptotic-resistance of human osteosarcoma cell line HS-Os-1 against irradiation2003
- Author(s)
  小川恭弘
- Journal Title
  
  International Journal of Molecular Medicine 12
  
  Pages : 453-458
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591281
[Presentation] Safety and effectiveness of a new enzyme-targeting radiosensitization treatment (KORTUC II) for intratumoral injection for low-LET radioresistant tumors2015
- Author(s)
  Ogawa Y, Kubota K, Aoyama N, Nishioka A
- Organizer
  15th International Congress of Radaition Research
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-05-27
- Invited
- Data Source
  KAKENHI-PROJECT-25461916
[Presentation] Safety and effectiveness of a new enzyme-targeting radiosensitization treatment (KORTUC II) for intratumoral injection for low-LET radioresitant tumors2015
- Author(s)
  Ogawa Y, Kubota K, Aoyama N, Nishioka A
- Organizer
  15th International Congress of Radiation Reaserch
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2015-05-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461916
[Presentation] Non-surgical breast-conservation treatment using KORTUC for patients with stage I/II breast cancer2014
- Author(s)
  Ogawa Y,　Kubota K, Aoyama N, Nishioka A
- Organizer
  15th Asia-Oceaniaｎ Congress of Radiology
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2014-09-24
- Data Source
  KAKENHI-PROJECT-25461916
[Presentation] Safety and efficacy of intraoperative radiotherapy with image-guided enzyme targeting radiosensitization(KORTUC-IORT) for advanced pancreatic cancer2011
- Author(s)
  Nishioka A, Ogawa Y, Suzuki Y, Tadokoro M, Kariya S, Hamada N, Kubota K
- Organizer
  53^<rd> Annual Meeting of the American Society for Radiation Oncology
- Place of Presentation
  Miami Beach, USA
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21591610
[Presentation] KORTUC II. A new image-guided, enzyme-targeted, and breast cancer stem cell targeted radiosensitization treatment for patients with stage I and II breast cancers2011
- Author(s)
  Ogawa Y, Kubota K, Tadokoro M, Yamanishi T, Aoyama N, Suzuki Y, Iwasa H, Kariya S, Nogami M, Nishioka A
- Organizer
  53^<rd> Annual Meeting of the American Society for Radiation Oncology
- Place of Presentation
  Miami Beach, USA
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21591610
[Presentation] Safety and efficacy of new enzyme targeting intraoperative radiotherapy for locally advanced pancreatic cancer2010
- Author(s)
  Nishioka A, Ogawa Y, Kariya S, Miyatake K, Tadokoro M, Ue H, Matsui R, Hamada N, Kubota K
- Organizer
  52nd Annual Meeting of the American Society for Radiation Oncology
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-21591610
[Presentation] Evaluation of changes of tumor shadows and micro-calcifications on mammography following a new radiosensitization treatment(KORTUC II) for aged patients with breast cancer of stages I and II2010
- Author(s)
  Tsuzuki A, Ogawa Y, Kubota K, Nishioka A, Akima R, Tokuhiro S, Yaogawa S, Yamada Y, Sasaki T, Geshi H
- Organizer
  52nd Annual Meeting of the American Society for Radiation Oncology
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-02
- Data Source
  KAKENHI-PROJECT-21591610
[Presentation] Phase I study of intra-tumoral injection of a newly developed enzyme-targeting radiosensitizer(KORTUC)containing hydrogen peroxide…2009
- Author(s)
  小川恭弘
- Organizer
  Joint ECCO 15-34^<th> ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin, Germany ベルリン国際会議場
- Year and Date
  2009-09-22
- Data Source
  KAKENHI-PROJECT-21591610
[Presentation] New enzyme-targeting radiosensitization treatment using a newly-developed radiosensitizer containing hydrogen peroxide & sodium hyaluronate for topical tumor injection2007
- Author(s)
  小川恭弘, ほか
- Organizer
  19th International Congress on Anti Cancer Treatment
- Place of Presentation
  Paris, France
- Year and Date
  2007-02-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591382
[Presentation] New enzyme-targeting radiosensitization treatment using a newly-developed radiosensitizer containing hydrogen peroxide & sodium hyaluronate for topical tumor injection2007
- Author(s)
  小川恭弘, ほか
- Organizer
  19th International Congress on Anti Cancer Treatment
- Place of Presentation
  Paris, France
- Year and Date
  2007-02-07
- Data Source
  KAKENHI-PROJECT-18591382
[Presentation] PET-CT-guided non-surgical chemo-radiosensitization treatment (KORTUC II) for patients with locally advanced breast cancer
- Author(s)
  小川恭弘、久保田　敬、青山信隆、仰木健太、田所導子、山西伴明、刈谷真爾、野上宗伸、西岡明人、宮村充彦
- Organizer
  第73回日本医学放射線学会学術発表会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-04-10 – 2014-04-13
- Data Source
  KAKENHI-PROJECT-25461916

1. 鈴木紀夫 (10010050)

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2. 新部英男 (90008293)

# of Collaborated Projects : 7results

# of Collaborated Products : 0results
3. 安藤興一 (00159526)

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# of Collaborated Products : 1results
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# of Collaborated Products : 9results
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10. SEGUCHI Harumichi (90030866)

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11. KARIYA Shinji (20314990)

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# of Collaborated Products : 6results
12. 平岡真寛 (70173218)

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13. 小松賢志 (80124577)

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19. SUZUKI Yusuke (40587531)

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20. AOYAMA Nobutaka (30614383)

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22. MORIO Kazuo (10618185)

# of Collaborated Projects : 1results

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23. YAOGAWA Shin (20618186)

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24. OGOSHI Shohei (60009587)

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25. TAKAHASHI Akira (10243825)

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26. TOKI Taiichi (90217472)

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27. SAIBARA Toshiji (60145125)

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28. AKISAWA Naoaki (00322280)

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29. TODA Katsumi (40197893)

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36. ONO Hiroto

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37. 山上卓士

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

OGAWA Yasuhiro 小川 恭弘

小川 泰弘 オガワ ヤスヒロ

Research Projects

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Development of a novel enzyme-targeting radiosensitizer (New KORTUC) using a gelatin-based hydrogel instead of a siduim hyaluronatePrincipal Investigator

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Identification of the therapeutic effect of new enzyme-targeting radiosensitization treatment, KORTUC for tumor stem cellsPrincipal Investigator

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Identification of a new apoptotic pathway of radiation-induced apoptosis of human peripheral lymphocytesPrincipal Investigator

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Reactive oxygen species producing site in radiation-induced apoptosis of human peripheral T cells: Involvement of lysosomal membrane destabilizationPrincipal Investigator

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癌の放射線・化学療法におけるG-CSF使用後の増加顆粒球の早期減少メカニズムPrincipal Investigator

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Review Section

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Mechanism of radiation-induced apoptosis of human peripheral T cellsPrincipal Investigator

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マウス移植腫瘍に対する放射線照射による癌関連遺伝子発現とアポトーシスの経時的変化Principal Investigator

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Immunohistochemical study of expression of several proto-oncogenes in cancer tissues from patients undergoing radiation therapyPrincipal Investigator

Principal Investigator

OGAWA Yasuhiro 小川恭弘

小川泰弘オガワヤスヒロ