Hnamura Ichiro 花村一朗

… Alternative Names

Hanamura Ichiro 花村一朗

HANAMYRA Ichiro 花村一朗

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Researcher Number	70440740
Other IDs	https://orcid.org/0000-0002-6681-8927
Affiliation (Current)	2025: 愛知医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 愛知医科大学, 医学部, 教授 2007 – 2008: Aichi Medical University, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator ゲノム編集 / CRISPR-cas9 / 標的治療 / 阻害剤 / 骨髄腫 / gene editing / CRISPR-Cas9 / target therapy / myeloma / RAS … More / KRAS / 遺伝子変異 / alemtuzumab / ヒト急性白血病 / アレンツムマブ / 化合物ライブラリー / アレンツズマブ / CRISPR-Csa9 / ITD / アレムツズマブ / 白血病 / CD52 / FLT3 / NF-κB / NIK / 1番染色体 / Iq21 / FISH / 染色体転座 / 1q21 / 多発性骨髄腫 / 癌 … More Except Principal Investigator 多発性骨髄腫 / 治療標的分子 / ゲノム編集 / 悪性化 / ノックアウトマウス / 分子病態 / PBK / 高活性NK細胞療法 / miR-1245とNK活性 / NKG2D 3’UTRゲノム編集 / 移植片対宿主病 / 遺伝子多型 / 造血幹細胞移植 / 白血病 / 創薬 / セルベースアッセイ / ゲノム異常 / 薬剤スクリーニング / 細胞生物学 / マウス / 治療 / トランスレーショナルリサーチ / 治療薬 / 造腫瘍性 / キナーゼ / 分子標的薬 / バイオマーカー / 細胞傷害性T細胞 / 多重免疫染色 / フローサイトメトリー / CCR4 / 免疫治療 / 免疫抑制 / がん微小環境 / 免疫療法 / PD-1 / FOXP3 / 頭頸部扁平上皮がん / 免疫抑制環境 / がん複合免疫治療 / 免疫チェックポイント / がん複合免疫療法 / がん免疫治療 / キイトルーダ / オプジーボ / 免疫チェックポイント阻害剤 / 制御性T細胞 Less

プライム編集と化合物ライブラリーを利用したRAS変異骨髄腫に対する新規治療法の開発Principal Investigator
- Principal Investigator
  
  花村一朗
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Aichi Medical University
Generation and Application of High-Activity NK Cells with Genetic Modification in the NKG2D 3-prime-UTR miR-1245 Binding Region
- Principal Investigator
  
  高見昭良
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Aichi Medical University
ゲノム編集を利用したKRAS変異骨髄腫に対する新規治療標的薬の探索Principal Investigator
- Principal Investigator
  
  花村一朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Aichi Medical University
Establishment of the platform for a drug discovery of multiple myeloma by targeting PBK-related signaling pathway
- Principal Investigator
  
  Ota Akinobu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kinjo Gakuin University
  Aichi Medical University
ADAMTS13 gene polymorphism genome editing creation of vascular endothelial cells and exploration for new leukemia therapies
- Principal Investigator
  
  Akiyoshi Takami
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Aichi Medical University
Development of the novel target therapy for leukemia with FLT3 mutations, using genetically modified FLT3-mutation knock-in human myeloid leukemia cellsPrincipal Investigator
- Principal Investigator
  
  Hanamura Ichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Aichi Medical University
Basic research for development of novel cancer immunotherapy based on improvement of the cancer immunosuppressive microenvironment
- Principal Investigator
  
  Suzuki Susumu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Aichi Medical University
Investigation of molecular mechanism by which PBK contributes to tumorigenesis in myeloma cells
- Principal Investigator
  
  Ota Akinobu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Aichi Medical University
Analysis of clinical feature and molecular pathogenesis of multiple myeloma with the gain of chromosome arm 1q21Principal Investigator
- Principal Investigator
  
  HANAMYRA Ichiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Aichi Medical University

All 2024 2023 2022 2021 2020 2019 2018 2009 2008 2007

All Journal Article Presentation Book Patent

[Book] 血液内科；遺伝子改変技術を用いた多発性骨髄腫の病態解析と新規治療法の開発2023
- Author(s)
  花村一朗
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-22K08516
[Book] 血液内科86(5) ; 688-932023
- Author(s)
  花村一朗
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-22K08516
[Book] 多発性骨髄腫診療ハンドブック2008
- Author(s)
  飯田真介、花村一朗, 他
- Total Pages
  163
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19790677
[Book] 多発性骨髄腫診療ハンドブック;3.診断と検査の実際 7)生物学的な予後因子、多発性骨髄腫診療ハンドブック2008
- Author(s)
  飯田真介ら編、花村一朗
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] Clinical practice guidelines for molecular tumor marker, 2nd edition review part 22024
- Author(s)
  Kikuchi Yoshinori, Shimada Hideaki. Hanamura Ichiro, Takahashi Hiroyuki, et al
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 29 Issue: 5 Pages: 512-534
- DOI
  10.1007/s10147-024-02497-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08516, KAKENHI-PROJECT-23K06917
[Journal Article] ARK5 enhances cell survival associated with mitochondrial morphological dynamics from fusion to fission in human multiple myeloma cells.2024
- Author(s)
  Karnan S, Hanamura I, Ota A, Vu LQ, Uchino K, Horio T, Murakami S, Mizuno S, Rahman ML, Wahiduzzaman M, Hasan MN, Biswas M, Hyodo T, Ito H, Suzuki A, Konishi H, Tsuzuki S, Hosokawa Y, Takami A.
- Journal Title
  
  Cell Death Discov.
  
  Volume: 10(1):56. Issue: 1 Pages: 56-56
- DOI
  10.1038/s41420-024-01814-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08294, KAKENHI-PROJECT-22K08516, KAKENHI-PROJECT-22K08985, KAKENHI-PROJECT-21K08426, KAKENHI-PROJECT-21K08427, KAKENHI-PROJECT-21K15579
[Journal Article] CAMK2D: a novel molecular target for BAP1-deficient malignant mesothelioma2023
- Author(s)
  Karnan Sivasundaram、Ota Akinobu、Murakami Hideki、Rahman Md. Lutfur、Wahiduzzaman Md、Hasan Muhammad Nazmul、Vu Lam Quang、Hanamura Ichiro、Inoko Akihito、Riku Miho、Ito Hideaki、Kaneko Yoshifumi、Hyodo Toshinori、Konishi Hiroyuki、Tsuzuki Shinobu、Hosokawa Yoshitaka
- Journal Title
  
  Cell Death Discovery
  
  Volume: 9 Issue: 1 Pages: 257-257
- DOI
  10.1038/s41420-023-01552-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14488, KAKENHI-PROJECT-22K06988, KAKENHI-PROJECT-22K08294, KAKENHI-PROJECT-22K08516, KAKENHI-PROJECT-21K08426
[Journal Article] Establishment of Mucoepidermoid Carcinoma Cell Lines from Surgical and Recurrence Biopsy Specimens2023
- Author(s)
  Yamanaka S, Suzuki S, Ito H, Sivasundaram K, Hanamura I, Okubo I, Yoshikawa K, Ono S, Takahara T, Satou A, Tsuzuki T, Ueda R, Ogawa T, Fujimoto Y.
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 24 Issue: 2 Pages: 1722-1722
- DOI
  10.3390/ijms24021722
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07203, KAKENHI-PROJECT-21K08427, KAKENHI-PROJECT-20K16205, KAKENHI-PROJECT-17K11301, KAKENHI-PROJECT-19K09292, KAKENHI-PROJECT-22K08516, KAKENHI-PROJECT-22K08985
[Journal Article] Autologous hematopoietic cell transplantation for myeloma patients with hepatitis B virus or hepatitis C virus in the era of novel agents2022
- Author(s)
  Mizuno Shohei、Takami Akiyoshi、Takamatsu Hiroyuki、Hanamura Ichiro、Shimazu Yutaka、Hangaishi Akira、Tsukada Nobuhiro、Kako Shinichi、Kikuchi Taku、Ota Shuichi、Shimizu Hiroaki、Iida Shinsuke、Yoshioka Satoshi、Sawa Masashi、Fukuda Takahiro、Kanda Yoshinobu、Atsuta Yoshiko、Kawamura Koji
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 1 Issue: 5 Pages: 1-10
- DOI
  10.1038/s41409-022-01640-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-21K15579, KAKENHI-PROJECT-21K08427
[Journal Article] Final analysis of randomized phase II study optimizing melphalan, prednisolone, bortezomib in multiple myeloma (JCOG1105)2022
- Author(s)
  Maruyama D, Iida S, Machida R, Kusumoto S, Fukuhara N, Yamauchi N, Miyazaki K, Yoshimitsu M, Kuroda J, Tsukamoto N, Tsujimura H, Usuki K, Yamauchi T, Utsumi T, Mizuno I, Takamatsu Y, Nagata Y, Ota S, Ohtsuka E, Hanamura I, Suzuki Y, Yoshida S, Yamasaki S, Suehiro Y, Kamiyama Y, Fukuhara S, Tsukasaki K, Nagai H.
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 9 Pages: 3267-3270
- DOI
  10.1111/cas.15484
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07239, KAKENHI-PROJECT-21K08427
[Journal Article] Successful preventive treatment with cyclosporine in a patient with relapsed/refractory immune-mediated thrombotic thrombocytopenic purpura: a case report and review of the literature2022
- Author(s)
  Uchino Kaori、Sakai Kazuya、Shinohara Saki、Matsuhisa Akifumi、Iida Yusuke、Nakano Yuta、Matsumura Saori、Kanasugi Jo、Takasugi Soichi、Nakamura Ayano、Horio Tomohiro、Murakami Satsuki、Mizuno Shohei、Yamamoto Hidesuke、Hanamura Ichiro、Matsumoto Masanori、Takami Akiyoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 1 Issue: 2 Pages: 1-10
- DOI
  10.1007/s12185-022-03319-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-21K15579, KAKENHI-PROJECT-21K08427, KAKENHI-PROJECT-22K08461
[Journal Article] Cytotoxicity of Callerya speciosa Fractions against Myeloma and Lymphoma Cell Lines2022
- Author(s)
  Lam Vu Quang、Anh La Hoang、Quan Nguyen Van、Xuan Tran Dang、Hanamura Ichiro、Uchino Kaori、Karnan Sivasundaram、Takami Akiyoshi
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 7 Pages: 2322-2322
- DOI
  10.3390/molecules27072322
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-21K08427, KAKENHI-PROJECT-19K09292, KAKENHI-PROJECT-22K08985
[Journal Article] Efficacy and safety of modified BLd therapy for Japanese patients with transplant-ineligible multiple myeloma2022
- Author(s)
  Murakami Satsuki、Hanamura Ichiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: 116 Issue: 4 Pages: 563-569
- DOI
  10.1007/s12185-022-03379-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08427
[Journal Article] Multiple myeloma with high-risk cytogenetics and its treatment approach2022
- Author(s)
  Hanamura Ichiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: 115 Issue: 6 Pages: 762-777
- DOI
  10.1007/s12185-022-03353-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08427, KAKENHI-PROJECT-22K08516
[Journal Article] Synergistic Effects of Venetoclax and Daratumumab on Antibody-Dependent Cell-Mediated Natural Killer Cytotoxicity in Multiple Myeloma2021
- Author(s)
  Nakamura Ayano、Suzuki Susumu、Kanasugi Jo、Ejiri Masayuki、Hanamura Ichiro、Ueda Ryuzo、Seto Masao、Takami Akiyoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 19 Pages: 10761-10761
- DOI
  10.3390/ijms221910761
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-21K08427
[Journal Article] CD52 is a novel target for the treatment of FLT3-ITD-mutated myeloid leukemia2021
- Author(s)
  Karnan Sivasundaram、Hanamura Ichiro、Uchino Kaori、Murakami Satsuki、Wahiduzzaman Md、Quang Vu Lam、Rahman Md Lutfur、Hasan Muhammad Nazmul、Hyodo Toshinori、Konishi Hiroyuki、Tsuzuki Shinobu、Yoshikawa Kazuhiro、Suzuki Susumu、Ueda Ryuzo、Ejiri Masayuki、Hosokawa Yoshitaka、Takami Akiyoshi
- Journal Title
  
  Cell Death Discovery
  
  Volume: 7 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41420-021-00446-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-19K08825, KAKENHI-PROJECT-18K14703, KAKENHI-PROJECT-19K08668, KAKENHI-PROJECT-21K08426, KAKENHI-PROJECT-21K08427, KAKENHI-PROJECT-19K09292
[Journal Article] Donor UNC-93 Homolog B1 genetic polymorphism predicts survival outcomes after unrelated bone marrow transplantation.2021
- Author(s)
  Uchino K, Vu Quang L, Mizuno S, Horio T, Yamamoto H, Hanamura I, Kodera Y, Luis Espinoza J, Onizuka M, Kashiwase K, Morishima Y, Fukuda T, Doki N, Miyamura K, Mori T, Morishita E, Nakao S, Takami A
- Journal Title
  
  Genes and Immunity
  
  Volume: 24 Issue: 1 Pages: 1-9
- DOI
  10.1038/s41435-021-00122-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16965, KAKENHI-PROJECT-18K07442, KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-21K08427, KAKENHI-PROJECT-21K15579
[Journal Article] Chromosomal translocation t(11;14) and p53 deletion induced by the CRISPR/Cas9 system in normal B cell-derived iPS cells2021
- Author(s)
  Yusuke Azami, Naohiro Tsuyama, Yu Abe, Misaki Sugai-Takahashi, Ken-Ichi Kudo, Akinobu Ota, Karnan Sivasundaram , Moe Muramatsu, Tomonari Shigemura, Megumi Sasatani, Yuko Hashimoto, Shigehira Saji, Kenji Kamiya, Ichiro Hanamura, Takayuki Ikezoe, Masafumi Onodera, Akira Sakai.
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 5216-5216
- DOI
  10.1038/s41598-021-84628-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08738, KAKENHI-PROJECT-20K20310, KAKENHI-PROJECT-20K21846, KAKENHI-PROJECT-19K17275, KAKENHI-PROJECT-17H00785, KAKENHI-PROJECT-18H02844, KAKENHI-PROJECT-18K08342, KAKENHI-PROJECT-18K11647, KAKENHI-PROJECT-21K07681, KAKENHI-PROJECT-21K08426, KAKENHI-PROJECT-19K09292
[Journal Article] Primary cutaneous methotrexate-associated B-cell lymphoproliferative disorders other than EBV-positive mucocutaneous ulcer: clinical, pathological, and immunophenotypic features2021
- Author(s)
  Satou Akira、Banno Shogo、Kohno Kei、Takahara Taishi、Takahashi Emiko、Nobata Hironobu、Iwagaitsu Shiho、Watanabe Daisuke、Hanamura Ichiro、Takami Akiyoshi、Ito Yasuhiko、Nakamura Shigeo、Tsuzuki Toyonori
- Journal Title
  
  Pathology
  
  Volume: - Issue: 5 Pages: 595-601
- DOI
  10.1016/j.pathol.2020.10.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16204, KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-21K08427
[Journal Article] Pretreatment Immature Platelet Fraction as a Surrogate of Reticulated Platelets Predicts the Response to Corticosteroids in Adults with Immune Thrombocytopenia2021
- Author(s)
  Takami Akiyoshi、Mizuno Shohei、Nakamura Ayano、Kanasugi Jo、Yamamoto Hidesuke、Vu?Quang Lam、Nakagami Yuya、Nakano Yuta、Yamada Saki、Matsumura Saori、Takasugi Souichi、Uchino Kaori、Horio Tomohiro、Murakami Satsuki、Oohigashi Yuka、Nakayama Takayuki、Tani Hiroya、Enomoto Megumi、Hanamura Ichiro
- Journal Title
  
  Acta Haematologica
  
  Volume: 144 Issue: 3 Pages: 345-349
- DOI
  10.1159/000510460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-20K08721, KAKENHI-PROJECT-21K08427
[Journal Article] Cytopenia associated with copper deficiency2021
- Author(s)
  Uchino Kaori、Quang Lam Vu、Enomoto Megumi、Nakano Yuta、Yamada Saki、Matsumura Saori、Kanasugi Jo、Takasugi Soichi、Nakamura Ayano、Horio Tomohiro、Murakami Satsuki、Goto Mineaki、Mizuno Shohei、Yamamoto Hidesuke、Watarai Masaya、Hanamura Ichiro、Takami Akiyoshi
- Journal Title
  
  eJHaem
  
  Volume: 2 Issue: 4 Pages: 729-737
- DOI
  10.1002/jha2.278
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-21K08427
[Journal Article] Bi-allelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells2020
- Author(s)
  Kanasugi J, Hanamura I, Ota A, Karnan S, Vu LQ, Mizuno S, Wahiduzzaman M, Rahman ML, Hyodo T, Konishi H, Tsuzuki S, Hosokawa Y, Takami A
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 5 Pages: 999-999
- DOI
  10.1111/cas.14386
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08342, KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-19K09292, KAKENHI-PROJECT-18K14703, KAKENHI-PROJECT-17K07263
[Journal Article] CRISPR-Casシステムを用いた骨髄腫の悪性化に関わる分子機構の解明2020
- Author(s)
  太田明伸, 花村一朗, 細川好孝
- Journal Title
  
  Precision Medicine
  
  Volume: 4(1) Pages: 60-64
- Data Source
  KAKENHI-PROJECT-18K08342
[Journal Article] Combining T‐cell‐based immunotherapy with venetoclax elicits synergistic cytotoxicity to B‐cell lines in vitro2020
- Author(s)
  Murakami Satsuki、Suzuki Susumu、Hanamura Ichiro、Yoshikawa Kazuhiro、Ueda Ryuzo、Seto Masao、Takami Akiyoshi
- Journal Title
  
  Hematological Oncology
  
  Volume: 38 Issue: 5 Pages: 705-714
- DOI
  10.1002/hon.2794
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-18K07277, KAKENHI-PROJECT-17K11301
[Journal Article] Novel Interleukin-6 Inducible Gene PDZ-Binding Kinase Promotes Tumor Growth of Multiple Myeloma Cells2020
- Author(s)
  Ota Akinobu、Hanamura Ichiro、Karnan Sivasundaram、Inaguma Shingo、Takei Norio、Lam Vu Quang、Mizuno Shohei、Kanasugi Jo、Wahiduzzaman Md、Rahman Md Lutfur、Hyodo Toshinori、Konishi Hiroyuki、Tsuzuki Shinobu、Ikeda Hiroshi、Takami Akiyoshi、Hosokawa Yoshitaka
- Journal Title
  
  Journal of Interferon & Cytokine Research
  
  Volume: 40 Issue: 8 Pages: 389-405
- DOI
  10.1089/jir.2020.0111
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-19K09292, KAKENHI-PROJECT-18K07060, KAKENHI-PROJECT-18K08342, KAKENHI-PROJECT-20K06613, KAKENHI-PROJECT-17K07263
[Journal Article] CRISPR-Casシステムを用いたゲノム編集と骨髄腫の新たな悪性化因子の同定2020
- Author(s)
  太田明伸, 花村一朗, 細川好孝
- Journal Title
  
  Precision Medicine
  
  Volume: 3(6) Pages: 571-575
- Data Source
  KAKENHI-PROJECT-18K08342
[Journal Article] Identification of CD24 as a potential diagnostic and therapeutic target for malignant pleural mesothelioma2020
- Author(s)
  KarnanS, Ota A, Murakami H, Rahman ML, Hasan 　MN, Wahiduzzaman MD, Hanamura I, Vu LQ, Inoko A, Hyodo T, Konishi H, Tsuzuki S, Hosokawa Y.
- Journal Title
  
  Cell Death Discovery
  
  Volume: 18 Issue: 1 Pages: 127-139
- DOI
  10.1038/s41420-020-00364-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08668, KAKENHI-PROJECT-19K09292, KAKENHI-PROJECT-18K07031, KAKENHI-PROJECT-18K08342, KAKENHI-PROJECT-20K06613, KAKENHI-PROJECT-17K07263
[Journal Article] 多発性骨髄腫の進展に関わる分子機構とPBKの関与2019
- Author(s)
  太田明伸, 花村一朗
- Journal Title
  
  BIO Clinica
  
  Volume: 34(6) Pages: 86-92
- Data Source
  KAKENHI-PROJECT-18K08342
[Journal Article] 多発性骨髄腫におけるPBK 発現の意義と治療標的としての可能性2019
- Author(s)
  太田明伸，花村一朗，細川好孝
- Journal Title
  
  BIO Clinica
  
  Volume: 34(13) Pages: 65-69
- Data Source
  KAKENHI-PROJECT-18K08342
[Journal Article] Establishment and characterization of CRISPR/Cas9-mediated NF2(-/-) human mesothelial cell line: Molecular insight into fibroblast growth factor receptor 2 in malignant pleural mesothelioma2019
- Author(s)
  Wahiduzzaman Md、Karnan Sivasundaram、Ota Akinobu、Hanamura Ichiro、Murakami Hideki、Inoko Akihito、Rahman Md Lutfur、Hyodo Toshinori、Konishi Hiroyuki、Tsuzuki Shinobu、Hosokawa Yoshitaka
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 1 Pages: 180-193
- DOI
  10.1111/cas.13871
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08342, KAKENHI-PROJECT-17K07263
[Journal Article] Immunomodulatory and Metabolic Changes after Gnetin-C Supplementation in Humans.2019
- Author(s)
  Nakagami Y, Suzuki S, Espinoza JL, Vu Quang L, Enomoto M, Takasugi S, Nakamura A, Nakayama T, Tani H, Hanamura I, Takami A
- Journal Title
  
  Nutrients
  
  Volume: 11 Issue: 6 Pages: 1403-1403
- DOI
  10.3390/nu11061403
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07277, KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-17K09944
[Journal Article] 多発性骨髄腫の進展に関わる分子機構とPBKの関与2019
- Author(s)
  太田明伸、花村一朗
- Journal Title
  
  BIO Clinica
  
  Volume: 451 Pages: 86-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08342
[Journal Article] Novel combined Ato-C treatment synergistically suppresses proliferation of Bcr-Abl-positive leukemic cells in vitro and in vivo2018
- Author(s)
  Wahiduzzaman Md、Ota Akinobu、Karnan Sivasundaram、Hanamura Ichiro、Mizuno Shohei、Kanasugi Jo、Rahman Md Lutfur、Hyodo Toshinori、Konishi Hiroyuki、Tsuzuki Shinobu、Takami Akiyoshi、Hosokawa Yoshitaka
- Journal Title
  
  Cancer Letters
  
  Volume: 433 Pages: 117-130
- DOI
  10.1016/j.canlet.2018.06.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08342, KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-17K07263
[Journal Article] Establishment and characterization of a novel vincristine-resistant diffuse large B-cell lymphoma cell line containing the 8q24 homogeneously staining region2018
- Author(s)
  Mizuno S、Hanamura I、Ota Akinobu、Karnan S、Kanasugi J、Nakamura A、Takasugi S、Uchino Ki、Horio T、Goto、Murakami S、Gotou M、Yamamoto H、Watarai M、Shikami M、Hosokawa Y、Miwa H、Taniwaki M、Ueda R、Nitta M、Takami A
- Journal Title
  
  FEBS Open Bio
  
  Volume: 8 Issue: 12 Pages: 1977-1991
- DOI
  10.1002/2211-5463.12538
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08342, KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-16K09856
[Journal Article] Growth inhibition of AML cells with specific chromosome abnormalities by monoclonal antibodies to receptors for vascular endothelial growth factor2009
- Author(s)
  N Imai, I Hanamura, et.al.
- Journal Title
  
  Leukemia Res (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] Growth inhibition of AML cells with specific chromosome abnormalities by monoclonal antibodies to receptors for vascular endothelial growth factor2009
- Author(s)
  Imai N, Miwa H, Shikami M, Suganuma K, Gotoh M, Hiramatsu A, Wakabayashi M, Watarai M, Hanamura I, Imamura A, Mihara H, Shitara K, Shibuya M, Nitta M.
- Journal Title
  
  Leukemia Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 多発性骨髄腫発症の分子機構に関する研究の進展2008
- Author(s)
  花村一朗、飯田真介
- Journal Title
  
  血液・腫瘍科(科学評論社) 57(2)
  
  Pages: 139-147
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 多発性骨髄腫発症の分子機構に関する研究の進展2008
- Author(s)
  花村一朗、飯田真介
- Journal Title
  
  血液・腫瘍科 57(2)
  
  Pages: 139-147
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 造血器疾患治療の新しい潮流;多発性骨髄腫の最新治療・治療の動向2008
- Author(s)
  花村一朗
- Journal Title
  
  Mebio(メジカルビュー社) 25(2)
  
  Pages: 108-123
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 多発性骨髄腫に対する分子標的療法up-date、サリドマイド2008
- Author(s)
  花村一朗
- Journal Title
  
  血液・腫瘍科 57(3)
  
  Pages: 278-284
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 多発性骨髄腫の最新治療・治療の動向2008
- Author(s)
  花村一朗・飯田真介
- Journal Title
  
  Mebio(メジカルビュー社) 25(2)
  
  Pages: 108-123
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 骨髄腫患者の治療のために ; 治療の実際・新規薬剤2008
- Author(s)
  花村一朗、飯田真介
- Journal Title
  
  臨床腫瘍プラクティス 4(3)
  
  Pages: 226-231
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 多発性骨髄腫に対する分子標的療法up-date、サリドマイド2008
- Author(s)
  花村一朗
- Journal Title
  
  血液・腫瘍科(科学評論社) 57(3)
  
  Pages: 278-284
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 多発性骨髄腫2007
- Author(s)
  花村一朗
- Journal Title
  
  成人病と成人習慣病(東京医学社) 37(2)
  
  Pages: 229-236
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genesmapping to chromosome 1.2007
- Author(s)
  Shaughnessy JD Jr, Hanamura I, Crowley J, Barlogie B. et al
- Journal Title
  
  Blood 109(6)
  
  Pages: 2276-2284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.2007
- Author(s)
  Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Zhan F, Lenz G, Hanamura I, Wright G, Xiao W, Dave S, Hurt EM, Tan B, Zhao H, Stephens O, Santra M, Williams DR, Dang L, Barlogie B, Shaughnessy JD Jr, Kuehl WM, Staudt LM.
- Journal Title
  
  Cancer Cell. 12(2)
  
  Pages: 115-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1.2007
- Author(s)
  Shaughnessy JD Jr, Zhan F, Burington BE, Huang Y, Colla S, Hanamura I, Stewart JP, Kordsmeier B, Randolph C, Williams DR, Xiao Y, Xu H, Epstein J, Anaissie E, Krishna SG, Cottler-Fox M, Hollmig K, Mohiuddin A, Pineda-Roman M, Tricot G, van Rhee F, Sawyer J, Alsayed Y, Walker R, Zangari M, Crowley J, Barlogie B.
- Journal Title
  
  Blood. 109(6)
  
  Pages: 2276-2284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] Frequent engagement of the classical and alternative NF-kB pathways by diverse genetic abnormalities in multiple myeloma.2007
- Author(s)
  Hanamura I, Shaughnessy JD Jr, Kuehl WM, Staudt LM. et al
- Journal Title
  
  Cancer Cell 12(2)
  
  Pages: 115-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 多発性骨髄腫 ; 分子標的となりうる分子病態2007
- Author(s)
  花村一朗
- Journal Title
  
  日本臨床(日本臨床社) 65(12)
  
  Pages: 2202-2208
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 多発性骨髄腫;自家移植併用大量化学療法後のthalidomideの有用性に関する第III相試験2007
- Author(s)
  花村一朗
- Journal Title
  
  血液・腫瘍科(科学評論社) 54(1)
  
  Pages: 20-26
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] MGUSから骨髄腫への発症と進展の分子機構2007
- Author(s)
  花村一朗
- Journal Title
  
  血液・腫瘍科(科学評論社) 55(2)
  
  Pages: 234-240
- Data Source
  KAKENHI-PROJECT-19790677
[Journal Article] 多発性骨髄腫;治療標的の対象となる分子病態2007
- Author(s)
  花村一朗
- Journal Title
  
  日本臨床(日本臨床社) 65(12)
  
  Pages: 2202-2208
- Data Source
  KAKENHI-PROJECT-19790677
[Patent] ＲＡＳ遺伝子変異体癌治療薬2022
- Inventor(s)
  シバスンダランカルナン、太田明伸、花村一朗、細川好孝
- Industrial Property Rights Holder
  シバスンダランカルナン、太田明伸、花村一朗、細川好孝
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-169541
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21K08426
[Presentation] DISCOVERY OF NOVEL TARGETED DRUGS FOR K-RAS-MUTATED MYELOMA USING ISOGENIC K-RASMUTANT CELLS2024
- Author(s)
  Ichiro Hanamura, Karnan Sivasundaram, Akinobu Ota, Keichiro Mihara, Yoshitaka Hosokawa, Akiyoshi Takami
- Organizer
  EHA2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08516
[Presentation] 再発難治性血栓性血小板減少性紫斑病患者におけるシクロスポリンの有用性2021
- Author(s)
  内野かおり山田早紀中野雄太松村沙織金杉丈高杉壮一中村文乃村上五月堀尾知弘水野昌平山本英督花村一朗酒井和哉松本雅則高見昭良
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08427
[Presentation] メトトレキサート関連リンパ増殖性疾患（ホジキンリンパ腫）の検討2021
- Author(s)
  村上五月、坂野章吾、花村一朗、高見昭良
- Organizer
  第61回リンパ網内系学会
- Data Source
  KAKENHI-PROJECT-21K08427
[Presentation] 肝炎ウィルス(HBV、HCV)感染を伴う多発性骨髄腫患者の自家造血細胞移植成績2021
- Author(s)
  水野昌平、高見昭良、花村一朗、河村浩二、島津裕、半下石明、塚田信弘、賀古真一、菊池拓、太田秀一、土岐典子、飯田真介、吉岡聡、澤正吏、福田隆浩、神田善伸、熱田由子、高松博幸
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08427
[Presentation] 赤芽球癆を合併した血管免疫芽球性T細胞リンパ腫2021
- Author(s)
  堀尾知弘水野昌平内野かおり山本英督村上五月高杉壮一中村文乃金杉丈松村沙織中野雄太花村一朗高見昭良
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08427
[Presentation] メトトレキサート関連リンパ増殖性疾患（ホジキンリンパ腫）の検討2021
- Author(s)
  村上五月,　坂野章吾,　佐藤啓,　花村一朗,　山本英督,　水野昌平,　堀尾知弘,　内野かおり,　高見昭良
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08427
[Presentation] CD52 is a novel target for the treatment of FLT3-ITD mutated leukemia2021
- Author(s)
  花村一朗, カルナンシバンスンダラン, 太田明伸, 鈴木進, 高杉壮一, 中村文乃, 高橋美裕希, 村上五月, 上田龍三, 細川好孝, 高見昭良
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08825
[Presentation] ベネトクラクスは BCL2 高発現の多発性骨髄腫細胞株に対するダラツムマブの抗体依存性細胞傷害活性を増強させる2021
- Author(s)
  中村文乃、鈴木進、瀬戸加大、高杉壮一、金杉丈、花村一朗、上田龍三、高見昭良
- Organizer
  第46回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08427
[Presentation] Synergistic Effect of Venetoclax for Antibody Dependent Cell Cytotoxicity By Daratumumab2020
- Author(s)
  Ayano Nakamura, Susumu Suzuki, Masao Seto, Souichi Takasugi, Jo Kanasugi, Ichiro Hanamura, Ryuzo Ueda, Akiyoshi Takami
- Organizer
  62nd ASH annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07277
[Presentation] CRISPRCas9を用いたNF2及びCDKN2Aノックアウトヒト中皮腫細胞株の樹立と分子生物学的解析2019
- Author(s)
  Sivasundaram Karnan, Akinobu ota, Ichiro Hanamura, Hideki Murakami, Toshinori Hyodo, Wahiduzzanan Md, Hiroyuki Konishi , Shinobu Tsuzuki, Yoshitaka Hosokawa
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K08342
[Presentation] 骨髄腫細胞におけるPBZ binding kinaseの腫瘍促進作用と治療標的分子としての可能性2019
- Author(s)
  太田明伸、花村一朗、Karnan Sivasundaram、高見昭良、細川好孝
- Organizer
  第44回日本骨髄腫学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08342
[Presentation] Biallelic Loss of FAM46C Promotes the Proliferation of Multiple Myeloma Cells with Concomitant Upregulation of P13K-AKT Signaling2019
- Author(s)
  Jo Kanasugi, Ichiro Hanamura, Akinobu Ota, Sivasundaram Karnan, Lam Quang Vu, Yoshitaka Hosokawa, Akiyoshi Takami
- Organizer
  第10回日本血液学会（JSH）国際シンポジウム
- Data Source
  KAKENHI-PROJECT-18K08342
[Presentation] Role of PBK in multiple myeloma cell growth: implication of PBK in novel molecular targets for anti-myeloma therapy2019
- Author(s)
  太田明伸, 花村一朗, KARNAN Sivasundaram, 高見昭良, 細川好孝
- Organizer
  第44回日本骨髄腫学会
- Data Source
  KAKENHI-PROJECT-18K08342
[Presentation] p16/NF2遺伝子の欠損により発現の誘導される悪性中皮腫特異的分子の同定2019
- Author(s)
  シバスンダランカルナン、太田明伸、花村一朗、村上秀樹、兵頭寿典、小西裕之、都築忍、細川好孝
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08342
[Presentation] Chromosomal translocation t(11;14) and p53 deletion in B cell-derived iPS cells by CRISPR/Cas92019
- Author(s)
  Aki Yanagi, Naohiro Tsuyama, Misaki Sugai, Yu Abe, Yukari Yanai, Akinobu Ota, Karnan Sivasundaram, Lobna Alkebsi, Moe Muramatsu, Tomonari Shigemura, Megumi Sasatani, Yuko Hashimoto, Kenji Kamiya, Ichiro Hanamura, Takayuki Ikezoe, Masafumi Onodera, Akira Sakai.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08342
[Presentation] Introduction of Chromosomal Translocation t(11; 14) and a p53 Deletion into Normal B Cell-derived iPSCs to Elucidate the Cellular Origin of Myeloma Cells.2019
- Author(s)
  Yanagi A, Tsuyama N, Sugai M, Abe Y, Azami Y, Yanai Y, Ota A, Sivasundaram K, Muramatsu M, Shigemura T, Sasatani M, Hashimot Y, Kamiya K, Hanamura I, Ikezoe T, Onodera M, Sakai A.
- Organizer
  61th ASH Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08342
[Presentation] 骨髄腫細胞のレナリドマイド耐性に関連する付加的ゲノム異常と遺伝子発現変化の基礎的検討2018
- Author(s)
  太田明伸, 花村一朗, KARNAN Sivasundaram, 高見昭良, 細川好孝
- Organizer
  第43回日本骨髄腫学会
- Data Source
  KAKENHI-PROJECT-18K08342
[Presentation] 多発性骨髄腫の腫瘍増殖におけるPDZ binding kinaseの関与2018
- Author(s)
  太田明伸、花村一朗、シバスンダランカルナン、小西裕之、都築忍、細川好孝
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08342
[Presentation] P16/NF2 遺伝子の欠損により発現の誘導される悪性中皮腫特異的分子の同定2018
- Author(s)
  シバスンダランカルナン、太田明伸、花村一朗、村上秀樹、ムハマドワヒドッジャマン、兵頭寿典、小西裕之、都築忍、細川好孝
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08342
[Presentation] CD8 single-positive ATLLの一例2008
- Author(s)
  爾見雅人、渡會雅也、平松明人、後藤麻友子、菅沼和人、今井敬和、若林基弘、花村一朗、今村明、三原英嗣、三輪啓志、仁田正和
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] Energy Metabolism of Leukemia Cells : Glycolysis Vs. Oxidative Phosphorylation2008
- Author(s)
  Hiroshi Miwa, Kazuto Suganuma, Masato Shikami, Norikazu Imai, Mayuko Sakai, Akihito Hiramatsu, Hidesuke Yamamoto, Motohiro Wakabayashi, Masaya Watarai, Ichiro Hanamura, Akira Imamura, Hidetsugu Mihara, Masakazu Nitta
- Organizer
  第50回アメリカ血液学会総会
- Place of Presentation
  米国サンフランシスコ
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] 急性骨髄性白血病細胞における解糖系優位のエネルギー代謝について2008
- Author(s)
  菅沼和人、三輪啓志、今井敬和、爾見雅人、後藤麻友子、平松明人、山本英督、若林基弘、渡会雅也、花村一朗、今村明、三原英嗣、仁田正和
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] 14q32転座関連遺伝子mRNA発現に基づく病型分類は骨髄腫患者の生命予後予測に有用である2008
- Author(s)
  稲垣淳、飯田真介、森芙美子、伊藤旭、田島恵美、三田貴臣、矢野寛樹、李政樹、粥川哲、丁建民、楠本茂、石田高司、花村一朗、速水芳仁、小松弘和、稲垣宏、上田龍三
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] Energy Metabolism of Leukemia Cells : Glycolysis Vs Oxidative Phosphorylation2008
- Author(s)
  K Suganuma. I Hanamura, et.al.
- Organizer
  第50回アメリカ血液学会総会
- Place of Presentation
  米国、サンフランシスコ
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] 内科的治療が有効であった本態性血小板血症に合併した大動脈血栓症の一例2008
- Author(s)
  山本英督、西巻春明、今井敬和、菅沼和人、後藤麻友子、平松明人、若林基弘、渡会雅也、花村一朗、爾見雅人、今村明、三原英嗣、三輪啓志、仁田正和、大圓修身
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] 抗VEGF受容体中和抗体のAML細胞への効果は核型特異的である2007
- Author(s)
  今井敬和、花村一朗, etc
- Organizer
  第69回日本血液学会総会・第49回日本臨床血液学会総会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] 染色体転座関連遺伝子発現に基づく病型分類は骨髄腫患者の生命予後予測に有用である2007
- Author(s)
  稲垣淳、花村一朗, etc
- Organizer
  第32回日本骨髄腫研究会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] MPO染色自動血算機はAPL分化誘導療法中の残存病変の評価に有用である2007
- Author(s)
  平松明人、花村一朗, etc
- Organizer
  第69回日本血液学会総会・第49回日本臨床血液学会総会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] 治療抵抗性成人T細胞性白血病/リンパ腫に対し、HLA一致同胞間RISTが有効である2007
- Author(s)
  爾見雅人、花村一朗, etc
- Organizer
  第69回日本血液学会総会・第49回日本臨床血液学会総会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] 自己末梢血幹細胞移植後、免疫学的機序による血小板減少症および赤芽球癆を合併した多発性骨髄腫の一例2007
- Author(s)
  伊藤公人、花村一朗, etc
- Organizer
  第69回日本血液学会総会・第49回日本臨床血液学会総会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19790677
[Presentation] 急性リンパ性白血病の移植後第1寛解期にHLA一致血縁者同種骨髄移植後急性骨髄性白血病(M0)を発症した一例2007
- Author(s)
  今村明、花村一朗, etc
- Organizer
  第69回日本血液学会総会・第49回日本臨床血液学会総会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19790677

1. Ota Akinobu (30438048)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
2. シバスンダランカルナン (30557096)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. Suzuki Susumu (70518422)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. Akiyoshi Takami (80324078)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
5. 武井則雄 (50523461)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NITTA Masakazu (70128669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. IIDA Shinsuke (50295614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. TANIWAKI Masafumi (80163640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小川徹也 (40334940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 佐野塁 (50813846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. エスピノザホルヘルイス (30621213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. GOTO Mayuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. JOHN Shaughnessy

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YAMAUCHI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 陸美穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 内野かおり

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 細川好孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 津山尚宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 坂井晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 阿部悠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 佐藤啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hnamura Ichiro 花村 一朗

Hanamura Ichiro 花村 一朗

HANAMYRA Ichiro 花村 一朗

Research Projects

Research Products

Co-Researchers

プライム編集と化合物ライブラリーを利用したRAS変異骨髄腫に対する新規治療法の開発Principal Investigator

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Generation and Application of High-Activity NK Cells with Genetic Modification in the NKG2D 3-prime-UTR miR-1245 Binding Region

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ゲノム編集を利用したKRAS変異骨髄腫に対する新規治療標的薬の探索Principal Investigator

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Establishment of the platform for a drug discovery of multiple myeloma by targeting PBK-related signaling pathway

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ADAMTS13 gene polymorphism genome editing creation of vascular endothelial cells and exploration for new leukemia therapies

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Development of the novel target therapy for leukemia with FLT3 mutations, using genetically modified FLT3-mutation knock-in human myeloid leukemia cellsPrincipal Investigator

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Basic research for development of novel cancer immunotherapy based on improvement of the cancer immunosuppressive microenvironment

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Investigation of molecular mechanism by which PBK contributes to tumorigenesis in myeloma cells

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Analysis of clinical feature and molecular pathogenesis of multiple myeloma with the gain of chromosome arm 1q21Principal Investigator

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[Book] 血液内科；遺伝子改変技術を用いた多発性骨髄腫の病態解析と新規治療法の開発2023

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[Book] 血液内科86(5) ; 688-932023

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[Book] 多発性骨髄腫診療ハンドブック2008

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Total Pages

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Data Source

[Book] 多発性骨髄腫診療ハンドブック;3.診断と検査の実際 7)生物学的な予後因子、多発性骨髄腫診療ハンドブック2008

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[Journal Article] Clinical practice guidelines for molecular tumor marker, 2nd edition review part 22024

Author(s)

Hnamura Ichiro 花村一朗

Hanamura Ichiro 花村一朗

HANAMYRA Ichiro 花村一朗