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WATANABE Masami  渡部 昌実

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… Alternative Names

渡部 昌実  ワタナベ マサミ

渡部 昌美  ワタナベ マサミ

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Researcher Number 70444677
Other IDs
Affiliation (Current) 2025: 岡山大学, 医療開発領域, 教授
Affiliation (based on the past Project Information) *help 2015 – 2023: 岡山大学, 大学病院, 教授
2011 – 2014: 岡山大学, 大学病院, 准教授
2010 – 2014: 岡山大学, 岡山大学病院, 准教授
2010: 岡山大学, 病院, 准教授
Review Section/Research Field
Principal Investigator
Urology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Tumor biology
Except Principal Investigator
Urology / Basic Section 56030:Urology-related / Medium-sized Section 52:General internal medicine and related fields / Tumor biology / Periodontal dentistry / Tumor biology
Keywords
Principal Investigator
幹細胞 / 間葉系幹細胞 / 細胞骨格 / 再生 / 腎臓 / 再生医学 / 癌 / 尿路性器癌 / microtubule / in vivo投与モデル … More / Dynamin / in vivo投与法 / エンドサイトーシス / in vivo投与 / 細胞内輸送 / 癌創薬 / 細胞移植法 / 組織除去 / 局所注入 / 細胞移植 / 前立腺 / 腫瘍学 / がん制御遺伝子 / 代謝 / 悪性形質 / SGTA / 男性ホルモン / REIC/Dkk-3 / 内分泌療法抵抗性 / 前立腺癌 / 分化 / 抗癌免疫 / 遺伝子治療 / 膀胱癌 … More
Except Principal Investigator
再生医学 / 幹細胞 / REIC/DKK-3 / 抗体 / 癌 / 再生 / 前立腺癌 / 癌ワクチン / 遺伝子治療 / 膀胱癌 / がん / 癌微小環境 / 代謝 / 免疫逃避 / 腫瘍免疫応答 / 骨髄由来免疫抑制細胞 / 内容放射線療法 / 画像診断 / ジルコニウム89 / PET / 動物モデル / 排尿平滑筋 / 免疫活性 / 抗癌免疫制御 / 制限増殖型アデノウイルスベクター / 抗癌免疫活性化 / 限増殖型アデノウイルスベクター / 分化 / 腎幹細胞 / 病的ストレス / 腎移植 / Emmprin / 液性免疫 / CD147 / 腫瘍学 / CD147 / 癌治療 / 平滑筋再生 / 尿失禁 / シグナル伝達 / 細胞 / S100A8/A9受容体 / S100A8/A9 / 転移 / 炎症 / 再生医療 / 男性ホルモン / アンドロゲン / アポトーシス誘導 / REIC/Dkk遺伝子 / 小胞体ストレス / P-glycoprotein / 抗癌剤耐性 / 平滑筋細胞 / 尿道括約筋 / iPS細胞 / REIC/Dkk3 / 細胞傷害性Tリンパ球 / 骨髄系免疫制御細胞 / REIC/Dkk3 / 骨髄系免疫抑制細胞 / がん転移 / 慢性感染 / 歯周病 / 癌転移 / 慢性炎症 / 歯周炎 / 診断法 / GFP発現プラスミド試薬 / ウイルス製剤 / 遺伝子発現プラスミド / 蛍光蛋白(GFP) / 癌診断 / プラスミド / ウイルスベクター / 緑色蛍光タンパク質 / アクチン / dynasore / 遊走 / 浸潤 / ダイナミン Less
  • Research Projects

    (21 results)
  • Research Products

    (96 results)
  • Co-Researchers

    (40 People)
  •  Elucidation of the mechanism of effector cell exhaustion release using tumor local metabolic modification proteins.

    • Principal Investigator
      定平 卓也
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Okayama University
  •  Unraveling the anti-cancer immune evasion mechanism of immune suppressive cells and exploring the basis for innovative cancer therapy

    • Principal Investigator
      HUANG Peng
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Okayama University
  •  Zr-89標識イメージング技術に基づく次世代抗体医薬の創生プラットフォームの形成

    • Principal Investigator
      佐々木 崇了
    • Project Period (FY)
      2019 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Okayama University
  •  Elucidation of molecular transport control systems based on cytoskeleton dynamics and new developments in innovative cancer drug discovery.Principal Investigator

    • Principal Investigator
      Watanabe Masami
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Okayama University
  •  Creation and application of micturition smooth muscle stem cells for bladder regeneration

    • Principal Investigator
      Watanabe Toyohiko
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Regeneration strategy of the functional renal corpuscle using renal stem cellsPrincipal Investigator

    • Principal Investigator
      Watanabe Masami
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Development of novel anti-cancer immune therapies targeting CD147 antigen

    • Principal Investigator
      Kobayashi Yasuyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Analysis of pathological stress control mechanism in kidney tissue stem cells

    • Principal Investigator
      Araki Moto
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Elucidation of the unitary regulation on the malignant transformation and androgen insensitivity in prostate cancer.Principal Investigator

    • Principal Investigator
      Watanabe Masami
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Okayama University
  •  Development of novel cancer vaccine therapy using oncolytic Ad-REIC

    • Principal Investigator
      huang peng
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Critical role of newly identified S100A8/A9 receptors in lung specific cancer metastasis

    • Principal Investigator
      Sakaguchi Masakiyo
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Okayama University
  •  Establishment and regenerative research of urinary smooth muscle stem cells for urethral sphincter

    • Principal Investigator
      Watanabe Toyohiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Establishment and applicational research of androgen producing stem cells

    • Principal Investigator
      Sugimoto Morito
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Induction and isolation of renal stem cells and establishment of foundation for renal regeneration research.Principal Investigator

    • Principal Investigator
      Watanabe Masami
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  A new therapeutic medicine based on the investigation of membrane transporter

    • Principal Investigator
      EBARA Shin
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Investigation of the mechanisms of personalized-cancer vaccination by REIC/Dkk-3 based gene therapy.

    • Principal Investigator
      KUMON Hiromi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Basic research of smooth muscle cells generated from induced pluripotent stem cells for urethral tissue engineering.

    • Principal Investigator
      WATANABE Toyohiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  The role of dynamin in actin dynamics: Development of anticancer drugs inhibiting dynamin function

    • Principal Investigator
      ABE Tadashi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Okayama University
  •  Development of new diagnostic methods for bladder cancer using GFP expressing adenovirus vector

    • Principal Investigator
      KAKU Haruki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  How periodontitis can affect prostate cancer metastasis?

    • Principal Investigator
      TANIMOTO Ichiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  Development of novel intravesical agents for the treatment of refractory superficial bladder cancerPrincipal Investigator

    • Principal Investigator
      WATANABE Masami
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University

All 2024 2023 2022 2021 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book Patent

  • [Book] REIC/Dkk-3 gene therapy2011

    • Author(s)
      Watanabe M, Kaku H, Huan g P, Kumon H, Nasu Y
    • Publisher
      Nihon Rinsho
    • Data Source
      KAKENHI-PROJECT-22791473
  • [Book] Suicide gene and immuno gene therapy for prostate cancer2011

    • Author(s)
      Nasu Y, Sasaki K, Kumon H, Kaku H, Watanabe M
    • Publisher
      Nihon Rinsho
    • Data Source
      KAKENHI-PROJECT-22791473
  • [Book] 前立腺癌(第2 版)-基礎・臨床研究のアップデート2011

    • Author(s)
      渡部昌実、賀来春紀、黄 鵬 、那 須 保 友 、公文裕巳
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Book] 前立腺癌の治療 遺伝子治療 自殺遺伝子・免疫遺伝子を用いた遺伝子治療2011

    • Author(s)
      那須保友、佐々木克己、賀来春紀、渡部昌実、公文裕巳
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] The current status and novel advances of boron neutron capture therapy clinical trials2024

    • Author(s)
      Zhou T, Igawa K, Kasai T, Sadahira T, Wang W, Watanabe T, Bekku K, Katayama S, Iwata T, Hanafusa T, Xu A, Araki M, Michiue H, Huang P.
    • Journal Title

      Am J Cancer Res .

      Volume: 14 Pages: 429-447

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09371
  • [Journal Article] Pacsin 2-dependent N-cadherin internalization regulates the migration behaviour of malignant cancer cells2023

    • Author(s)
      Haymar Wint, Jianzhen Li, Tadashi Abe, Hiroshi Yamada, Takumi Higaki, Yasutomo Nasu, Masami Watanabe, Kohji Takei, Tetsuya Takeda
    • Journal Title

      Journal of Cell Science

      Volume: 136(10) Issue: 10

    • DOI

      10.1242/jcs.260827

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0180, KAKENHI-PROJECT-22K06580, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-19H01064
  • [Journal Article] Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells.2023

    • Author(s)
      Yuma Gohara, Nahoko Tomonobu, Rie Kinoshita, Junichiro Futami, Lena Audebert, Youyi Chen, Ni Luh Gede Yoni Komalasari, Fan Jiang, Chikako Yoshizawa, Hitoshi Murata, Ken-Ichi Yamamoto, Masami Watanabe, Hiromi Kumon, Masakiyo Sakaguchi
    • Journal Title

      Journal of molecular medicine (Berlin, Germany)

      Volume: 101 Issue: 4 Pages: 431-447

    • DOI

      10.1007/s00109-023-02292-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-20K07636, KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-19H01064, KAKENHI-PROJECT-23K27439
  • [Journal Article] Exploration of the protein-dependent mechanism of Lactobacillus crispatus GAI98322 to prevent recurrent cystitis2023

    • Author(s)
      Watanabe Tomofumi、Sadahira Takuya、Hirakawa Hidetada、Huang Peng、Zhou Tianyun、Iwata Takehiro、Sekito Takanori、Ishii Ayano、Watanabe Masami、Araki Motoo
    • Journal Title

      Journal of Infection and Chemotherapy

      Volume: 29 Issue: 10 Pages: 1001-1004

    • DOI

      10.1016/j.jiac.2023.06.013

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09473, KAKENHI-PROJECT-21K09371
  • [Journal Article] Identification of MICALL2 as a Novel Prognostic Biomarker Correlating with Inflammation and T Cell Exhaustion of Kidney Renal Clear Cell Carcinoma2022

    • Author(s)
      Lin Wenfeng、Chen Wenwei、Zhong Jisheng、Ueki Hideo、Xu Abai、Watanabe Masami、Araki Motoo、Liu Chunxiao、Nasu Yasutomo、Huang Peng
    • Journal Title

      Journal of Cancer

      Volume: 13 Issue: 4 Pages: 1214-1228

    • DOI

      10.7150/jca.66922

    • NAID

      120007188355

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09371
  • [Journal Article] Dkk3/REIC Deficiency Impairs Spermiation, Sperm Fibrous Sheath Integrity and the Sperm Motility of Mice2022

    • Author(s)
      Xue Ruizhi、Lin Wenfeng、Fujita Hirofumi、Sun Jingkai、Kinoshita Rie、Ochiai Kazuhiko、Futami Junichiro、Watanabe Masami、Ohuchi Hideyo、Sakaguchi Masakiyo、Tang Zhengyan、Huang Peng、Nasu Yasutomo、Kumon Hiromi
    • Journal Title

      Genes

      Volume: 13 Issue: 2 Pages: 285-285

    • DOI

      10.3390/genes13020285

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09625, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-21K09371, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-22H04923
  • [Journal Article] Dual-Functional PLGA Nanoparticles Co-Loaded with Indocyanine Green and Resiquimod for Prostate Cancer Treatment2021

    • Author(s)
      Lin Wenfeng、Li Chaoming、Xu Naijin、Watanabe Masami、Xue Ruizhi、Xu Abai、Araki Motoo、Sun Ruifen、Liu Chunxiao、Nasu Yasutomo、Huang Peng
    • Journal Title

      International Journal of Nanomedicine

      Volume: Volume 16 Pages: 2775-2787

    • DOI

      10.2147/ijn.s301552

    • NAID

      120007034434

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09371
  • [Journal Article] Discovery and Validation of Nitroxoline as a Novel STAT3 Inhibitor in Drug-resistant Urothelial Bladder Cancer2021

    • Author(s)
      Lin Wenfeng、Sun Jingkai、Sadahira Takuya、Xu Naijin、Wada Koichiro、Liu Chunxiao、Araki Motoo、Xu Abai、Watanabe Masami、Nasu Yasutomo、Huang Peng
    • Journal Title

      International Journal of Biological Sciences

      Volume: 17 Issue: 12 Pages: 3255-3267

    • DOI

      10.7150/ijbs.63125

    • NAID

      120007141452

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09371
  • [Journal Article] The Cell Cycle Checkpoint Gene, RAD17 rs1045051, Is Associated with Prostate Cancer Risk2021

    • Author(s)
      Sun J, Lin W, Wang Q, Sakai A, Xue R, Watanabe M, Liu C, Sadahira T, Nasu Y, Xu A, Huang P.
    • Journal Title

      Acta Medica Okayama

      Volume: 75 Issue: 4 Pages: 415-421

    • DOI

      10.18926/AMO/62379

    • NAID

      120007146060

    • URL

      https://ousar.lib.okayama-u.ac.jp/62379

    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09371
  • [Journal Article] Dynamin 1 is important for microtubule organisation and stabilisation in glomerular podocytes2020

    • Author(s)
      The Mon La , Tachibana, H., Li, S.A., Abe, T., Seiriki, S., Nagaoka, H., Takashima, E., Takeda, T., Ogawa, D., Makino, S., Asanuma, K., Watanabe, M., Tian, X., Ishibe, S., Sakane, A., Sasaki, T., Wada, J., Takei, K., Yamada, H.
    • Journal Title

      FASEB Journal

      Volume: 34 Issue: 12 Pages: 16449-16463

    • DOI

      10.1096/fj.202001240rr

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07084, KAKENHI-PROJECT-20K08591, KAKENHI-PROJECT-19KK0180, KAKENHI-PROJECT-19H01064, KAKENHI-PROJECT-18H02651, KAKENHI-PROJECT-18H02823, KAKENHI-PROJECT-19H03225, KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-18K07198
  • [Journal Article] Endogenous Leu332Gln mutation in p53 disrupts the tetramerization ability in a canine mammary gland tumor cell line.2018

    • Author(s)
      Ochiai K, Azakami D, Morimatsu M, Hirama H, Kawakami S, Nakagawa T, Michishita M, Egusa AS, Sasaki T, Watanabe M, Omi T.
    • Journal Title

      Oncol Rep

      Volume: 40 Pages: 488-494

    • DOI

      10.3892/or.2018.6409

    • NAID

      120006551592

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04297, KAKENHI-PROJECT-18H02334
  • [Journal Article] Induction of Expandable Adipose-Derived Mesenchymal Stem Cells from Aged Mesenchymal Stem Cells by a Synthetic Self-Replicating RNA.2018

    • Author(s)
      Miyagi-Shiohira C, Nakashima Y, Kobayashi N, Kitamura S, Saitoh I, Watanabe M, Noguchi H
    • Journal Title

      Int J Mol Sci.

      Volume: 6 Issue: 11 Pages: 3489-3489

    • DOI

      10.3390/ijms19113489

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08244, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10435, KAKENHI-PROJECT-16K10436, KAKENHI-PROJECT-16K15689
  • [Journal Article] Expression of tumor suppressor REIC/Dkk-3 by a newly improved adenovirus vector with insertion of an hTERT promoter at the 3’-side of the transgene2017

    • Author(s)
      1.Putranto EW, Kinoshita R, Watanabe M, Sadahira T, Murata H, Yamamoto KI, Futami J, Kataoka K, Inoue Y, Ruma IM, Sumardika IW, Youyi C, Kubo M, Sakaguchi Y, Saito K, Nasu Y, Kumon H, Huh NH, Sakaguchi M
    • Journal Title

      Oncol Lett

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26290039
  • [Journal Article] Overexpression of REIC/Dkk-3 suppresses the expression of CD147 and inhibits the proliferation of human bladder cancer cells.Oncol Lett.2017

    • Author(s)
      Horikawa Y, Watanabe M, Sadahira T, Ariyoshi Y, Kobayashi Y, Araki M, Wada K, Ochiai K, Li SA, Nasu Y.
    • Journal Title

      Oncol Lett

      Volume: 14 Issue: 3 Pages: 3223-3228

    • DOI

      10.3892/ol.2017.6548

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10590
  • [Journal Article] Canine REIC/Dkk-3 interacts with SGTA and restores androgen receptor signalling in androgen-independent prostate cancer cell lines2017

    • Author(s)
      Kato Yuiko、Ochiai Kazuhiko、Kawakami Shota、Nakao Nobuhiro、Azakami Daigo、Bonkobara Makoto、Michishita Masaki、Morimatsu Masami、Watanabe Masami、Omi Toshinori
    • Journal Title

      BMC Veterinary Research

      Volume: 13 Issue: 1 Pages: 170-170

    • DOI

      10.1186/s12917-017-1094-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08053, KAKENHI-PROJECT-26292161, KAKENHI-PROJECT-15H04297, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15K07754
  • [Journal Article] Distant Bystander Effect of REIC/DKK3 Gene Therapy Through Immune System Stimulation in Thoracic Malignancies.2017

    • Author(s)
      Suzawa K, Shien K, Peng H, Sakaguchi M, Watanabe M, Hashida S, Maki Y, Yamamoto H, Tomida S, Soh J, Asano H, Tsukuda K, Nasu Y, Kumon H, Miyoshi S, Toyooka S.
    • Journal Title

      Anticancer Res

      Volume: 37 Issue: 1 Pages: 301-307

    • DOI

      10.21873/anticanres.11321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382
  • [Journal Article] Robust cancer-specific gene expression by a novel cassette with hTERT and CMV promoter elements2017

    • Author(s)
      Sakaguchi M, Sadahira T, Ueki H, Kinoshita R, Murata H, Yamamoto KI, Futami J, Nasu Y, Ochiai K, Kumon H, Huh NH, Watanabe M
    • Journal Title

      Oncol Rep

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26290039
  • [Journal Article] Promising therapeutic efficacy of a novel REIC/Dkk-3 expressing adenoviral vector for hepatocellular carcinoma.2017

    • Author(s)
      Sawahara H, Shiraha H, Uchida D, Kato H, Kato R, Oyama A, Nagahara T, Iwamuro M, Horiguchi S, Tsutsumi K, Mandai M, Mimura T, Wada N, Takeuchi Y, Kuwaki K, Onishi H, Nakamura S, Watanabe M, Sakaguchi M, et al.
    • Journal Title

      J Gastroenterol Hepatol.

      Volume: - Issue: 10 Pages: 1769-1777

    • DOI

      10.1111/jgh.13757

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-25220206, KAKENHI-PROJECT-15H04974, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-15K08999, KAKENHI-PROJECT-15K09001
  • [Journal Article] The canine prostate cancer cell line CHP-1 shows over-expression of the co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein α2016

    • Author(s)
      Azakami, D., Nakahira, R., Kato, Y., Michishita, M., Kobayashi, M., Onozawa, E., Bonkobara, M., Kobayashi, M., Takahashi, K., Watanabe, M., Ishioka, K., Sako, T., Ochiai, K., and Omi, T.
    • Journal Title

      Veterinary and Compapative Oncology

      Volume: 印刷中 Issue: 2 Pages: 557-562

    • DOI

      10.1111/vco.12199

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07754, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15H04297
  • [Journal Article] MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding.2016

    • Author(s)
      Ruma IM, Putranto EW, Kondo E, Murata H, Watanabe M, Huang P, Kinoshita R, Futami J, Inoue Y, Yamauchi A, Sumardika IW, Youyi C, Yamamoto K, Nasu Y, Nishibori M, Hibino T, Sakaguchi M.
    • Journal Title

      Clin Exp Metastasis

      Volume: 33 Issue: 6 Pages: 609-627

    • DOI

      10.1007/s10585-016-9801-2

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K20093, KAKENHI-PROJECT-15K10201, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K15245
  • [Journal Article] Novel REIC/Dkk-3-encoding adenoviral vector as a promising therapeutic agent for pancreatic cancer.2016

    • Author(s)
      Sawahara H, Shiraha H, Uchida D, Kato H, Nagahara T, Iwamuro M, Kataoka J, Horiguchi S, Watanabe M, Sakaguchi M, Takaki A, Nouso K, Nasu Y, Kumon H, Okada H
    • Journal Title

      Cancer Gene Ther

      Volume: 23 Issue: 8 Pages: 278-283

    • DOI

      10.1038/cgt.2016.31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K09001
  • [Journal Article] The induction of antigen-specific CTL by in situ Ad-REIC gene therapy.2016

    • Author(s)
      Ariyoshi Y, Watanabe M, Eikawa S, Yamazaki C, Sadahira T, Hirata T, Araki M, Ebara S, Nasu Y, Udono H, Kumon H.
    • Journal Title

      Gene Ther.

      Volume: gt.2016.7 Issue: 5 Pages: 408-414

    • DOI

      10.1038/gt.2016.7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26670237, KAKENHI-PROJECT-26290056, KAKENHI-PROJECT-15H04297, KAKENHI-PROJECT-26293352
  • [Journal Article] Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway.2016

    • Author(s)
      Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, Hashida S, Miyata-Takata T, Watanabe M, Suzawa K, Soh J, Youyi C, Sato H, Namba K, Torigoe H, Tsukuda K, Yoshino T, Miyoshi S, Toyooka S.
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 33319-33319

    • DOI

      10.1038/srep33319

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-26462182, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-26670644
  • [Journal Article] The cysteine-rich core domain of REIC/Dkk-3 is critical for its effect on monocyte differentiation and tumor regression.2015

    • Author(s)
      Kinoshita R, Watanabe M, Huang P, Li SA, Sakaguchi M, Kumon H, Futami J.
    • Journal Title

      Oncology Reports

      Volume: In press Issue: 6 Pages: 2908-2914

    • DOI

      10.3892/or.2015.3885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25861425, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-26290039
  • [Journal Article] Synergistic anti-pancreatic cancer immunological effects by treatment with REIC/DKK3 protein and peripheral blood mononuclear cells.2015

    • Author(s)
      Uchida D, Shiraha H, Kato H, Sawahara H, Nagahara T, Iwamuro M, Kataoka J, Horiguchi S, Watanabe M, Takaki A, Nouso K, Nasu Y, Kumon H, Yamamoto K
    • Journal Title

      J Gastroenterol Hepatol

      Volume: - Issue: 6 Pages: 1154-1159

    • DOI

      10.1111/jgh.13259

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15H04297, KAKENHI-PROJECT-15H04974, KAKENHI-PROJECT-25220206
  • [Journal Article] A novel gene expression system strongly enhances the anticancer effects of a REIC/Dkk-3-encoding adenoviral vector2014

    • Author(s)
      Watanabe M., Sakaguchi M., Kinoshita R., Kaku H., Ariyoshi Y., Ueki H., Tanimoto R., Ebara S., Ochiai K., Futami J., Li SA., Huang P., Nasu Y., Huh NH., Kumon H
    • Journal Title

      Oncology Reports

      Volume: 31巻 Issue: 3 Pages: 1089-95

    • DOI

      10.3892/or.2013.2958

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24780313, KAKENHI-PROJECT-25462479, KAKENHI-PROJECT-25861425, KAKENHI-PROJECT-26290039
  • [Journal Article] Anti-Cancer Effects of REIC/Dkk-3-encoding Adenoviral Vector for the Treatment of Non-small Cell Lung Cancer2014

    • Author(s)
      Shien K, Tanaka N, Watanabe M, Soh J, Sakaguchi M, Matsuo K, Yamamoto H, Furukawa M, Asano H, Tsukuda K, Nasu Y, Huh NH, Miyoshi S, Kumon H, Toyooka S
    • Journal Title

      PLoS ONE

      Volume: 9 Issue: 2 Pages: e87900-e87900

    • DOI

      10.1371/journal.pone.0087900

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26670627
  • [Journal Article] Adenovirus-mediated REIC/Dkk-3 gene therapy: development of an autologous cancer vaccination therapy2014

    • Author(s)
      Watanabe M.,Nasu Y.,Kumon H.
    • Journal Title

      Oncology Letters

      Volume: 7 Pages: 595-601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Journal Article] Extract of Cordyceps militaris inhibits angiogenesis and suppresses tumor growth of human malignant melanoma cells.2014

    • Author(s)
      Ruma IMW, Putranto EW, Kondo E, Watanabe R, Saito K, Inoue Y, Yamamoto K, Nakata S,Kaihata M, Murata H and Sakaguchi M.
    • Journal Title

      Int J Oncol.

      Volume: 45(1) Issue: 1 Pages: 209-18

    • DOI

      10.3892/ijo.2014.2397

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25290062, KAKENHI-PROJECT-25460488, KAKENHI-PROJECT-25460490, KAKENHI-PROJECT-25670263, KAKENHI-PROJECT-26290039
  • [Journal Article] Adenovirus-mediated REIC/Dkk-3 gene therapy : development of an autologous cancer vaccination therapy2014

    • Author(s)
      Watanabe M., Nasu Y., Kumon H
    • Journal Title

      Oncology Letters

      Volume: 7巻 Issue: 3 Pages: 595-601

    • DOI

      10.3892/ol.2013.1777

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Journal Article] Adenovirus-mediated REIC/Dkk-3 gene therapy : Development of an autologous cancer vaccination therapy2013

    • Author(s)
      Watanabe M
    • Journal Title

      Oncology Letters

      Volume: 7(3) Pages: 595-601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] Cancer stem cell-likecharacteristics of a CD133+ subpopulation in the J82 human bladder cancer cell line2013

    • Author(s)
      Peng Huang, Masami Watanabe,Haruki Kaku
    • Journal Title

      Molecular and Clinical Oncology

      Volume: 1 Pages: 180-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] Assessment of antimicrobial prophylaxis to prevent perioperative infection in patients undergoing prostate brachytherapy : multicenter cohort study2013

    • Author(s)
      Watanabe T
    • Journal Title

      J Infect Chemother

      Volume: 19(5) Pages: 926-930

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] In vivo imaging of transplanted islets labeled with a novel cationic nanoparticle2013

    • Author(s)
      Oishi K, Miyamoto Y, Saito H, Murase K, Ono K, Sawada M, Watanabe M, Noguchi Y, Fujiwara T, Hayashi S, Noguchi H
    • Journal Title

      PLoS One

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] In vivo imaging of transplanted islets labeled with a novel cationic nanoparticle2013

    • Author(s)
      Watanabe M
    • Journal Title

      PLoS One

      Volume: 8(2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] Clinical significance of CD24 as a predictor of bladder cancer recurrence2013

    • Author(s)
      Chunxiao Liu, Shaobo Zheng, Haiyan Shen, Kai Xu, Jie Chen, Hulin Li, Yawen Xu, Abai Xu, Binshen Chen, Haruki Kaku, Yasutomo Nasu, Hiromi Kumon, Peng Huang, Masami Watanabe
    • Journal Title

      Oncology letters

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] Cancer stem cell-like characteristics of a CD133+ subpopulation in the J82 human bladder cancer cell line2013

    • Author(s)
      Watanabe M, Ueki H
    • Journal Title

      Molecular and Clinical Oncology

      Volume: 1(1) Pages: 180-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] Stabilization of Actin Bundles by a Dynamin 1/Cortactin Ring Complex Is Necessary for Growth Cone Filopodia2013

    • Author(s)
      Watanabe M
    • Journal Title

      J Neurosci

      Volume: 33(10) Pages: 4514-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] Testosterone replacement elevates the serum uric acid levels in patients with female to male gender identity disorder.2013

    • Author(s)
      Hiroaki Kurahashi, Masami Watanabe, Morito Sugimoto, Yuichi Ariyoshi, Sabina Mahmood, Motoo Araki, Kazushi Ishii, Yasutomo Nasu, Atsushi Nagai, Hiromi Kumon
    • Journal Title

      Endocrine Journal

      Volume: 60 Pages: 1321-1327

    • NAID

      130004770402

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462538
  • [Journal Article] The hTERT promoter enhances the antitumor activity of an oncolytic adenovirus under a hypoxic microenvironment2012

    • Author(s)
      Hashimoto Y, Tazawa H, Teraishi F, Kojima T, Watanabe Y, Uno F, Yano S, Urata Y, Kagawa S, Fujiwara T
    • Journal Title

      PLoS One

      Volume: 7

    • NAID

      120005232484

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] Pelvic surgeons caught in the meshes of the law2012

    • Author(s)
      Watanabe T
    • Journal Title

      Revies in Urology

      Volume: 14(1-2) Pages: 35-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] Implications of transcriptional factor, OCT-4, in human bladder malignancy and tumor recurrence2012

    • Author(s)
      Huang P Chen J Wang L Na Y Kaku H.Ueki H Sasaki K Yamaguchi K Zhang K Saika T Nasu Y Watanabe M, . Kumon H
    • Journal Title

      Med Oncol

      Volume: 29 Pages: 829-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] Ureteroscopic management of chronic unilateral hematuria : A single-center experience over 22 years2012

    • Author(s)
      Watanabe T
    • Journal Title

      PloS One

      Volume: 7(6)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] Preclinical safety and efficacy of in situ REIC/Dkk-3 gene therapy for prostate cancer2012

    • Author(s)
      Kawauchi K., Watanabe M., Kaku H., Huang P., Sasaki K., Sakaguchi M., Ochiai K., Huh NH., Nasu Y., Kumon H
    • Journal Title

      Acta Med Okayama

      Volume: 66巻 Pages: 7-16

    • NAID

      120003850603

    • URL

      http://escholarship.lib.okayama-u.ac.jp/amo/vol66/iss1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Journal Article] Implications of transcriptional factor2012

    • Author(s)
      Huang P, Chen J, Wang L, Na Y,Kaku H, Ueki H, Sasaki K, Yamaguchi K, Zhang K, Saika T, Nasu Y, Watanabe M, Kumon H
    • Journal Title

      OCT-4, in human bladder malignancy and tumor recurrence

      Volume: 29 Pages: 829-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer.2012

    • Author(s)
      Hirata et al.
    • Journal Title

      Int J Oncol.

      Volume: 41 Issue: 2 Pages: 559-564

    • DOI

      10.3892/ijo.2012.1503

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22501013, KAKENHI-PROJECT-22616004, KAKENHI-PROJECT-23370089, KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-23659213, KAKENHI-PROJECT-24390368, KAKENHI-PUBLICLY-24117711
  • [Journal Article] Partial sensitization of human bladder cancer cells to a gene-therapeutic adenovirus carrying REIC/Dkk-3 by downregulation of BRPK/PINK1.2012

    • Author(s)
      Jin Y, Murata H, Sakaguchi M, Kataoka K, Watanabe M, Nasu Y, Kumon H
    • Journal Title

      Huh NH. Oncol Rep.

      Volume: 27(3) Pages: 695-9

    • DOI

      10.3892/or.2011.1543

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441, KAKENHI-PROJECT-22791473, KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24390368, KAKENHI-PUBLICLY-24117711
  • [Journal Article] Preclinical biodistribution and safety study of REIC/Dkk-3 encoding adenovirus vector for prostate cancer gene therapy2012

    • Author(s)
      Watanabe M, Ueki H
    • Journal Title

      Oncol Rep

      Volume: 28(5) Pages: 1645-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer2012

    • Author(s)
      Hirata T, Watanabe M, Kaku H, Kobayashi Y, Yamada H, Sakaguchi M, Takei K, Huh NH, Nasu Y, Kumon H
    • Journal Title

      International Journal of Oncology

      Volume: 41 Pages: 559-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] Prevalence of pharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae among heterosexual men in Japan2012

    • Author(s)
      Watanabe T
    • Journal Title

      J Infect Chemother

      Volume: 18(5) Pages: 729-733

    • NAID

      10031120732

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] Preclinical biodistribution and safety study of REIC/Dkk-3 encoding adenovirus vector for prostate cancer gene therapy2012

    • Author(s)
      Sugimoto M Watanabe M, Kaku H, , , , , , , .Preclinical Li SA Noguchi H Ueki H Sakaguchi M Huh NH Nasu Y Kumon H
    • Journal Title

      Oncol Rep

      Volume: 28 Pages: 1645-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] A novel gene expression system for detecting viable bladder cancer cells2012

    • Author(s)
      Ueki H Watanabe M, Kaku H, , , , , , , , , , . Huang P Li SA Ochiai K Hirata T Noguchi H Yamada H Takei K Nasu Y Kashiwakura Y Kumon H
    • Journal Title

      International Journal of Oncology

      Volume: 41 Pages: 135-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] Preclinical safety and efficacy of in situ REIC/Dkk-3 gene therapy for prostate cancer2012

    • Author(s)
      Kawauchi K, Watanabe M, Kaku H, Huang P, Sasaki K, Sakaguchi M, Ochiai K, Huh NH, Nasu Y, Kumon H
    • Journal Title

      Acta Med Okayama

      Volume: 66(1) Pages: 7-16

    • NAID

      120003850603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791473
  • [Journal Article] Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy2012

    • Author(s)
      Sugimoto M., Watanabe M., Kaku H., Li SA., Noguchi H., Ueki H., Sakaguchi M., Huh NH., Nasu Y., Kumon H
    • Journal Title

      Oncol Rep

      Volume: 28巻 Issue: 5 Pages: 1645-1652

    • DOI

      10.3892/or.2012.2001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24390316, KAKENHI-PUBLICLY-24117711
  • [Journal Article] Laparoscopic-assisted tension-free vaginal mesh : An innovative approach to placing synthetic mesh transvaginally for surgical correction of pelvic organ prolapse2012

    • Author(s)
      Watanabe T
    • Journal Title

      Acta Med Okayama

      Volume: 66(1) Pages: 23-29

    • NAID

      120003850605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] Single Nucleotide Polymorphism WRN Leu1074Phe Is Associated with Prostate Cancer Susceptibility in Chinese Subjects2011

    • Author(s)
      Lei Wang, Haruki Kaku, Peng Huang, Kexin Xu, Kai Yang, Jiheng Zhang, Ming Li, Liping Xie, Xiaofeng Wang, Akiko Sakai, Masami Watanabe, Yasutomo Nasu, Kenji Shimizu, Hiromi Kumon, Yanqun Na
    • Journal Title

      Acta Med Okayama

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791473
  • [Journal Article] Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-12011

    • Author(s)
      Ochiai, K., Watanabe, M., Ueki, H., Huang, P., Fujii, Y., Nasu, Y., Sakaguchi, M., Huh, NH., Kashiwakura, Y., Kaku, H., and Kumon, H.
    • Journal Title

      Biochem. Biophy. Res. Com

      Volume: 412(2) Issue: 2 Pages: 391-395

    • DOI

      10.1016/j.bbrc.2011.07.109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791476, KAKENHI-PROJECT-23390382
  • [Journal Article] Implications of transcriptional factor, OCT-4, in human bladder malignancy and tumor recurrence2011

    • Author(s)
      Huang P, Chen J, Wang L, Na Y, Kaku H, Ueki H, Sasaki K, Yamaguchi K, Zhang K, Saika T, Nasu Y, Watanabe M, Kumon H
    • Journal Title

      Med Oncol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791473
  • [Journal Article] Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-12011

    • Author(s)
      Ochiai K, Watanabe M, et al
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 412 Pages: 391-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791473
  • [Journal Article] Advanced two-step transcriptional amplification as a novel method for cancer-specific gene expression and imaging.2011

    • Author(s)
      Watanabe M, Ueki H, Ochiai K, Huang P, Kobayashi Y, Nasu Y, Sasaki K, Kaku H, Kashiwakura Y, Kumon H
    • Journal Title

      Oncol Rep

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791473
  • [Journal Article] Nerve growth factor level in the prostatic fluid of patients with chronic prostatitis/chronic pelvic pain syndrome is correlated with symptom severity and response to treatment2011

    • Author(s)
      Watanabe T., Inoue, M., Sasaki, K.
    • Journal Title

      BJU Int

      Volume: 108(2) Pages: 248-251

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] Advanced two-step transcriptional amplification as a novel method for cancer-specific geneexpression and imaging2011

    • Author(s)
      Watanabe M, Ueki H
    • Journal Title

      Oncol Rep

      Volume: 26(4) Pages: 769-75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] Advanced two-step transcriptional amplification as a novel method for cancer-specific gene expression and imaging2011

    • Author(s)
      Watanabe M, Ueki H, Ochiai K, Huang P, Kobayashi Y, Nasu Y, Sasaki K,Kaku H, Kashiwakura Y, Kumon H.
    • Journal Title

      Oncol Rep

      Volume: 26 Pages: 769-75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] REIC/Dkk-3遺伝子治療2011

    • Author(s)
      渡部昌実, 賀来春紀, 他
    • Journal Title

      前立腺癌(第2版)-基礎・臨床研究のアップデート-

      Pages: 559-563

    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] Tumor growth and metastasis suppression by Glipr1 gene-modified macrophages in a metastatic prostate cancer model.2011

    • Author(s)
      Tabata K, Kurosaka S, Watanabe M, Edamura K, Satoh T, Yang G, Abdelfattah E, Wang J, Goltsov A, Floryk D, Thompson TC
    • Journal Title

      Gene Ther

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791473
  • [Journal Article] Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-12011

    • Author(s)
      Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H, Kumon H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 412(2) Pages: 391-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791473
  • [Journal Article] Potent antitumor effects of combined therapy with a telomerase-specific, replication-competent adenovirus(OBP-301)and IL-2 in a mouse model of renal cell carcinoma2010

    • Author(s)
      Huang P Kaku H, , , , , , Chen J Kashiwakura Y Saika T Nasu Y Urata Y Fujiwara T, Watanabe M, . Potent antitumor Kumon H
    • Journal Title

      Cancer Gene Ther

      Volume: 17 Pages: 484-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Journal Article] Impact of overactive bladder and lower urinary tract symptoms on sexual health in Japanese women2010

    • Author(s)
      Watanabe, T
    • Journal Title

      Int Urogynecol J Pelvic Floor Dysfunct

      Volume: 22(2) Pages: 165-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592369
  • [Journal Article] In vivo biological purging for lymph node metastasis of human colorectal cancer by telomerase-specific oncolytic virotherapy.2010

    • Author(s)
      Kojima T, Watanabe Y, Hashimoto Y, Kuroda S, Yamasaki Y, Yano S, Ouchi M, Tazawa H, Uno F, Kagawa S, Kyo S, Mizuguchi H, Urata Y, Tanaka N, Fujiwara T.
    • Journal Title

      Ann Surg

      Volume: 251 Pages: 1079-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Patent] トリアゾール誘導体の用途2021

    • Inventor(s)
      黄 鵬, 渡部昌実, 林 文鋒
    • Industrial Property Rights Holder
      黄 鵬, 渡部昌実, 林 文鋒
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-053244
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-21K09371
  • [Patent] REIC/Dkk-3タンパク質の部分領域ポリペプチド2011

    • Inventor(s)
      公文 裕巳, 渡部 昌実, 二見 淳一郎, 藤井 康之, 植木 英雄
    • Industrial Property Rights Holder
      岡山大学, 桃太郎源(株)
    • Industrial Property Rights Type
      特許
    • Filing Date
      2011-07-01
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Patent] REIC発現アデノウイルスベクター2011

    • Inventor(s)
      渡部 昌実, 公文 裕巳, 許 南浩, 阪口 政清
    • Industrial Property Rights Holder
      岡山大学, 桃太郎源(株)
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2011-117321
    • Filing Date
      2011-05-25
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Presentation] Reposition of the antibiotic nitroxoline as a novel STAT3 inhibitor for drug-resistant urothelial bladder cancer2021

    • Author(s)
      WENFENG LIN, Jingkai Sun, Takuya Sadahira, Motoo Araki, Masami Watanabe, Yasutomo Nasu, Peng Huang
    • Organizer
      AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09371
  • [Presentation] Real-time monitoring of tumor progression and drug responses in a preclinical mouse model of prostate cancer2016

    • Author(s)
      Peng Huang , Naijin Xu, Eiji Matsuura, Chunxiao Liu , Masami Watanabe, Hiromi Kumon  and Yasutomo Nasu
    • Organizer
      International Society for Cell and Gene Therapy of Cancer 2016
    • Place of Presentation
      seoul, Korea
    • Year and Date
      2016-11-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20093
  • [Presentation] Real-time monitoring of tumor progression and drug responses in a preclinical mouse model of prostate cancer2016

    • Author(s)
      Naijin Xu, Peng Huang , Eiji Matsuura, Chunxiao Liu , Masami Watanabe, Hiromi Kumon  and Yasutomo Nasu
    • Organizer
      Best ofASCO (The Singapore Scoiety of Oncology 2016)
    • Place of Presentation
      Singapore
    • Year and Date
      2016-07-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20093
  • [Presentation] Monitoring and imaging tumor progression and tracking drug response in a preclinical mouse model2016

    • Author(s)
      Peng Huang , Naijin Xu, Eiji Matsuura, Chunxiao Liu , Masami Watanabe, Hiromi Kumon  and Yasutomo Nasu
    • Organizer
      22nd Annual Meeting of Japan Society of Gene and Cell Therapy
    • Place of Presentation
      Tokyo
    • Year and Date
      2016-07-28
    • Data Source
      KAKENHI-PROJECT-15K20093
  • [Presentation] The proof of concept of REIC/Dkk-3 gene therapy for thoracic malignancies2016

    • Author(s)
      Shinichi Toyooka, Ken Suzawa, Kazuhiko Shien, Masakiyo Sakaguchi, Masami Watanabe, Peng Huang, Kei Namba, Hidejiro Torigoe, Hiroki Sato, Junichi Soh, Hiromasa Yamamoto, Yuho Maki, Kazunori Tsukuda, Shuta Tomida, Yasutomo Nasu, Hiromi Kumon, Shinichiro Miyoshi.
    • Organizer
      Tenth AACR-JCA Joint Conference
    • Place of Presentation
      Maui USA
    • Year and Date
      2016-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20093
  • [Presentation] Identification of a novel binding protein playing a critical role in HER2 activation in lung cancer cells2015

    • Author(s)
      Tomoaki Ohtsuka, Masakiyo Sakaguchi, Katsuyoshi Takata, Shinsuke Hashida, Mototsugu Watanabe, Ken Suzawa, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
    • Organizer
      AACR Annual Meeting 2015
    • Place of Presentation
      フィラデルフィア州、ペンシルバニア
    • Year and Date
      2015-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26290039
  • [Presentation] A super geneexpression system strongly enhances the anticancer effects of the REIC/Dkk-3 encoding adenoviral vector2013

    • Author(s)
      Watanabe M, et al
    • Organizer
      Annual Meeting of Japan Society of Gene Therapy
    • Place of Presentation
      Japan Okayama
    • Year and Date
      2013-07-05
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Presentation] Immunomodulation and anti-cancer activity of REIC/Dkk-3 protein2013

    • Author(s)
      Huang P.,Watanabe M.,Nasu Y.,Kaku H.,and Kumon H.
    • Organizer
      European Society of Gene and Cell Therapy
    • Place of Presentation
      Madrid, Spain
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Presentation] A phase I/II study of reduced expression in immortalized cells(REIC/Dkk-3)gene therapy for prostate cancer: Challenge to establish as a cancer vaccine2013

    • Author(s)
      Ariyoshi Y.,Watanabe M.,Sasaki K.,Hirata T.,Tanimoto R.,Kaku H.,Ebara S.,Watanabe T.,Nasu Y.,Kumon H.
    • Organizer
      Asian Pacific Prostate Society 2013
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Presentation] Analysis of combination therapy  of the adenovirus vector carrying REIC/Dkk-3(Ad-REIC)and the integrin antagonist cilengitide2013

    • Author(s)
      Simazu Y.,Kurozumi K.,Ichikawa T.,Fujii K.,Onishi M.,Ishida J.,Watanabe M.,Nasu Y.,Kumon H.,Date I.
    • Organizer
      Annual Meeting of Japan Society of Gene Therapy
    • Place of Presentation
      Okayama,Okayama Convention Center
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Presentation] 性同一性障害(GID FTM)における内分泌療法と筋肉量の検討2013

    • Author(s)
      松本裕子,杉本盛人,倉橋寛明,渡部昌実,石井和史,荒木元朗,江原伸,那須保友,公文裕巳
    • Organizer
      第11回日本泌尿器科学会総会
    • Place of Presentation
      さっぽろ芸術文化の館
    • Data Source
      KAKENHI-PROJECT-25462538
  • [Presentation] 前立腺癌に対するREIC遺伝子治療-自己癌ワクチン化療法の確立を目指して2013

    • Author(s)
      有吉勇一,平田武志,谷本竜太,佐々木克己,渡部昌実,江原 伸,那須保友,公文裕巳
    • Organizer
      泌尿器科分子・細胞研究会
    • Place of Presentation
      高知市
    • Year and Date
      2013-03-08
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Presentation] A super geneexpression system strongly enhances the anticancer effects of the REIC/Dkk-3 encoding adenoviral vector2013

    • Author(s)
      Watanabe M.,Sakaguchi M.,Kaku H.,Ueki H.,Ariyoshi Y.,Hirata T.,Yoshioka T.,Huang P.,Li S-A.,Nasu Y.,Huh N.,Kumon H.
    • Organizer
      Annual Meeting of Japan Society of Gene Therapy
    • Place of Presentation
      Okayama,Okayama Convention Center
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Presentation] Adenovirus-mediated REIC-Dkk-3 gene therapy induces tumor antigen-specific cytotoxic T-cell activation in mouse cancer models2013

    • Author(s)
      Ariyoshi Y.,Hirata T.,Watanabe M.,Tanimoto R.,Sasaki K.,Kaku H.,Ebara S.,Watanabe T.,Nasu Y.,Kumon H.
    • Organizer
      Annual Meeting of Japan Society of Gene Therapy
    • Place of Presentation
      Okayama,Okayama Convention Center
    • Data Source
      KAKENHI-PROJECT-23390382
  • [Presentation] 新規がん治療遺伝子REIC/Ckk-3 -がんワクチン機能を有する遺伝子医薬2012

    • Author(s)
      渡部昌実 那須保友 公文裕巳
    • Organizer
      BioJapan 2012 World Business Forum
    • Place of Presentation
      横浜
    • Year and Date
      2012-10-12
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Presentation] REIC/Dkk-3 encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer2012

    • Author(s)
      Hirata T, Watanabe M, Kaku H, Ebara S, Watanabe T, Nasu Y, Kumon H
    • Organizer
      日本泌尿器科学会西日本総会
    • Place of Presentation
      徳島
    • Year and Date
      2012-11-09
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Presentation] 前立腺癌に対する遺伝子治療 -新たな免疫療法の開発をめざした取り組み2011

    • Author(s)
      佐々木克己、那須保友、渡部昌実、賀来春紀、公文裕巳
    • Organizer
      第63回日本泌尿器科学会 西日本総会
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Presentation] A phase I/IIstudy of adenovirus mediated interleukin-12 gene therapy for hormone refractory prostate cancer :2011

    • Author(s)
      Sasaki K, Nasu Y, Kaku H, Watanabe M, Nose H, Kanbara D, Saika T, Kumon H
    • Organizer
      An interim report American Society of Clinical Oncology 2010 Genitourinary Cancers Symposium
    • Place of Presentation
      Orlando, Florida, U.S.A.
    • Year and Date
      2011-02-03
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Presentation] 前立腺癌に対するREIC 遺伝子治療2011

    • Author(s)
      黄 鵬,渡部昌実,賀来春紀,陳 潔,那須保友,公文裕巳
    • Organizer
      癌免疫外科研究会
    • Place of Presentation
      和歌山市
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-22591767
  • [Presentation] Critical role of Cytokeratin-19 in an oncogenic activation of HER2

    • Author(s)
      Tomoaki Ohtsuka, Masakiyo Sakaguchi, Katsuyoshi Takata, Shinsuke Hashida, Mototsugu Watanabe, Ken Suzawa, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜市、パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26290039
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    # of Collaborated Products: 7 results
  • 2.  NOGUCHI HIROFUMI (50378733)
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    # of Collaborated Products: 4 results
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