SAKAGUCHI-MIKAMI Akane 三上あかね

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三上あかねミカミアカネ

坂口あかね

MIKAMI (SAKAGUCHI) Akane 三上あかね

三上あかね(坂口あかね) ミカミアカネ

MIKAMI Akane 三上あかね

SAKAGUCHI Akane 坂口あかね

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Researcher Number	70469782
Other IDs
Affiliation (Current)	2025: 東京工科大学, 医療保健学部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2019: 東京工科大学, 医療保健学部, 講師 2014 – 2015: 東京工科大学, 医療保健学部, 講師 2011 – 2012: 東京工科大学, 応用生物学部, 助教 2008 – 2009: National Institute for Materials Science, 生体材料センター, NIMSポスドク研究員
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering / Biomedical engineering/Biological material science
Keywords	Principal Investigator 生体情報・計測 / 細胞内糖化 / 転写調節因子 / 糖化物 / 細胞内計測 / 細胞機能制御 / 腫瘍細胞 / 糖化関連疾病 / 細胞内モニタリング法 / 糖化関連物質応答性転写調節因子 … More / 細胞内モニタリング / 糖化 / 糖尿病 / 計測 / 生体情報 / 分子認識 / 発現制御 / 細胞センシング / 細胞内センシング Less

Development of intracellular multi-monitoring system and its application for analysis of glycation effect on tumor cellsPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI-MIKAMI Akane
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo University of Technology
Development of monitoring system for intracelular reactive carbon spices-related glycationPrincipal Investigator
- Principal Investigator
  
  MIKAMI (SAKAGUCHI) Akane
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo University of Technology
Development of intracellular glycated products monitoring systems for cellular functional regulation.Principal Investigator
- Principal Investigator
  
  MIKAMI Akane (SAKAGUCHI Akane)
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Technology
Design of novel transcriptional regulators for the development of an intracellular sensing and functional regulation platform in mammalian cellsPrincipal Investigator
- Principal Investigator
  
  MIKAMI Akane
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  National Institute for Materials Science

All 2020 2019 2017 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 『バイオセンサーのはなし』第3章11節’センサー細胞を用いた毒性評価’2012
- Author(s)
  軽部征夫、編著　(３章１１節　執筆担当　三上あかね)
- Publisher
  日刊工業新聞社
- Data Source
  KAKENHI-PROJECT-23700545
[Journal Article] Advancing the development of glycated protein biosensing technology: next-generation sensing molecules2015
- Author(s)
  Miho Kameya, Akane Sakaguchi-Mikami, Stefano Ferri, Wakako Tsugawa, Koji Sode
- Journal Title
  
  Journal of diabetes science and technology
  
  Volume: ９ Issue: 2 Pages: 183-191
- DOI
  10.1177/1932296814565784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26882046
[Journal Article] ヘモグロビンA1cのPOCT測定法の現状と展望2015
- Author(s)
  三上　あかね
- Journal Title
  
  臨床化学
  
  Volume: 44 Pages: 119-125
- Data Source
  KAKENHI-PROJECT-26882046
[Journal Article] Identification and functional analysis of fructosyl amino acid-binding protein from Gram-positive bacterium Arthrobacter sp2013
- Author(s)
  Sakaguchi-Mikami A, Ferri S, Katayama S, Tsugawa W, Sode K
- Journal Title
  
  J Appl Microbiol
  
  Volume: 114(5) Issue: 5 Pages: 1449-56
- DOI
  10.1111/jam.12152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700545
[Journal Article] Cloning and Characterization of Fructosamine-6-Kinase from Arthrobacter aurescens2013
- Author(s)
  Sakaguchi-Mikami A, Kameya M, Ferri S,Tsugawa W, Sode K
- Journal Title
  
  Appl BiochemBiotechnol
  
  Volume: 170 Issue: 3 Pages: 710-717
- DOI
  10.1007/s12010-013-0229-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700545
[Journal Article] Construction of a novel glucose-sensing molecule based on a substrate-binding protein for intracellularsensing2011
- Author(s)
  Sakaguchi-Mikami A, Yamazaki T, Tanigchi A, Sode K, Karube I.
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: 108 Issue: 4 Pages: 725-33
- DOI
  10.1002/bit.23006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700545
[Journal Article] Protein Engineering Approaches to Novel Glucose Sensing Elements Construction2010
- Author(s)
  T.Yamazaki, A.Sakaguchi
- Journal Title
  
  Indonesian Nanoletter 3(1)
  
  Pages: 44-46
- Data Source
  KAKENHI-PROJECT-20700389
[Journal Article] The Construction of a Glucose Sensing Luciferase2009
- Author(s)
  A.Taneoka, A.Sakaguchi-Mikami, T.Yamazaki, W.Tsugawa, K.Sode
- Journal Title
  
  Biosensors and Bioelectronics 25
  
  Pages: 76-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700389
[Journal Article] Construction of a novel transcriptional regulator based on a substrate binding protein : a probe for intracellular sensing and gene regulation systems2009
- Author(s)
  A.Sakaguchi-Mikami, A.Taniguchi, T.Yamazaki
- Journal Title
  
  Submitted
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700389
[Journal Article] 細菌由来基質結合タンパク質を用いた人工転写調節因子の設計2009
- Author(s)
  坂口あかね, 山崎智彦、谷口彰良
- Journal Title
  
  生体の科学 59(4)
  
  Pages: 313-319
- Data Source
  KAKENHI-PROJECT-20700389
[Journal Article] Glucose sensing luciferase2009
- Author(s)
  A.Taneoka, A.Sakaguchi-Mikami, T.Yamazaki, W.Tsugawa, K.Sode
- Journal Title
  
  Biosensors & Bioelectronics 25
  
  Pages: 76-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700389
[Journal Article] Engineering of ligand specificity of periplasmic binding protein for glucose sensing2008
- Author(s)
  A.Sakaguchi-Mikami, A.Taneoka, R.Yamoto, S.Ferri, K.Sode
- Journal Title
  
  Biotechnology Letters 30(8)
  
  Pages: 1453-1460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700389
[Journal Article] 細菌由来基質結合タンパク質を用いた人工転写調節因子の設計2008
- Author(s)
  坂口あかね, 山崎智彦、谷口彰良
- Journal Title
  
  生体の科学 59
  
  Pages: 313-319
- Data Source
  KAKENHI-PROJECT-20700389
[Journal Article] Engineering of ligand specificity of periplasmic binding protein for glucose sensing2008
- Author(s)
  A. Sakaguchi-Mikamim, A. Taneoka, R.Yamoto, S. Ferri, K. Sode
- Journal Title
  
  Biotechnology Letters 30(8)
  
  Pages: 1453-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700389
[Journal Article] Protein Engineering Approaches to Novel Glucose Sensing Elements Construction
- Author(s)
  T.Yamazaki, A.Sakaguchi
- Journal Title
  
  Indonesian Nanoletter (In press)
- Data Source
  KAKENHI-PROJECT-20700389
[Journal Article] Construction of a novel glucose sensing molecule based on a substrate-binding protein for intracellular sensing
- Author(s)
  A.Sakaguchi-Mikami, A.Taniguchi, K.Sode, T.Yamazaki
- Journal Title
  
  Biotechnology and Bioengineering in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] A Novel Monitoring System for Intracellular glycation2020
- Author(s)
  Akane Sakaguchi-Mikami, Maho Sakurai, Shoya Kojima, Yukimi Sugimoto, Misato Kashiba
- Organizer
  日本化学会第100回春季年会
- Data Source
  KAKENHI-PROJECT-17K01376
[Presentation] 土壌細菌由来新規糖化産物応答性転写調節因子2019
- Author(s)
  三上あかね、Yani Faozani Alli
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-17K01376
[Presentation] 新規糖化物応答転写調節因子に基づく細胞内糖化物モニタリング法の開発2017
- Author(s)
  金井知芙優、内田直恵、アリヤニ・ファオザニ、三上あかね
- Organizer
  第27回日本メイラード学会(女子栄養大学　埼玉)
- Data Source
  KAKENHI-PROJECT-17K01376
[Presentation] 細胞糖化マルチモニタリング用蛍光モニタリング法の開発2017
- Author(s)
  相上莉穂、廣原まゆ、三上あかね
- Organizer
  第27回日本メイラード学会(女子栄養大学　埼玉)
- Data Source
  KAKENHI-PROJECT-17K01376
[Presentation] 新規糖化タンパク質応答性転写調節因子の検索2017
- Author(s)
  金村孝太、綾野晃一、三上あかね
- Organizer
  第27回日本メイラード学会(女子栄養大学　埼玉)
- Data Source
  KAKENHI-PROJECT-17K01376
[Presentation] Development of a transcriptional factor for intracellular glycation monitoring system2015
- Author(s)
  Akane Sakaguchi-Mikami, Yani Faozani Alli, Isao Karube
- Organizer
  Biochemistry and Molecular Biology
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市中央区)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26882046
[Presentation] 糖化タンパク質バイオセンシング法の開発2015
- Author(s)
  三上　あかね
- Organizer
  日本臨床化学会関東支部総会
- Place of Presentation
  東京工科大学(東京都大田区)
- Year and Date
  2015-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-26882046
[Presentation] Biosensing of glycated proteins for health care2014
- Author(s)
  Akane Sakaguchi-Mikami
- Organizer
  UK-Japan Workshop on Biosensing Technologies for Innovative Healthcare
- Place of Presentation
  在日英国大使館(東京都千代田区)
- Year and Date
  2014-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-26882046
[Presentation] 細胞内糖化物応答性転写調節因子の検索2013
- Author(s)
  三上あかね、大矢修一、山崎智彦、軽部征夫
- Organizer
  第93日本化学会春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス、滋賀
- Data Source
  KAKENHI-PROJECT-23700545
[Presentation] 細胞内糖化物応答性転写調節因子の検索2013
- Author(s)
  三上あかね・大矢修一・山崎智彦・軽部征夫
- Organizer
  第 93 日本化学会春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス、滋賀
- Data Source
  KAKENHI-PROJECT-23700545
[Presentation] 細胞内糖化物測定用転写調節因子の設計2012
- Author(s)
  三上あかね、工藤芳、綾野晃一、山崎智彦、軽部征夫
- Organizer
  第92回日本化学会春季年会
- Place of Presentation
  慶応大学矢上・日吉キャンパス(神奈川)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-23700545
[Presentation] 新規糖化物応答性転写調節因子様タンパク質SocRのクローニング及び特性検討2012
- Author(s)
  大矢修一、軽部征夫、三上あかね
- Organizer
  第22回日本メイラード学会年会
- Place of Presentation
  東京農工大学、東京
- Data Source
  KAKENHI-PROJECT-23700545
[Presentation] 細胞内糖化物測定用転写調節因子の設計2012
- Author(s)
  三上　あかね、工藤芳、綾野晃一、山崎智彦、軽部征夫
- Organizer
  第92回日本化学会春季年会
- Place of Presentation
  慶応大学　矢上・日吉キャンパス (神奈川)
- Data Source
  KAKENHI-PROJECT-23700545
[Presentation] 糖化タンパク質計測用新規分子認識素子の探索と計測2012
- Author(s)
  三上あかね.
- Organizer
  第22回日本メイラード学会年会
- Place of Presentation
  東京農工大学、東京
- Data Source
  KAKENHI-PROJECT-23700545
[Presentation] Intracellular sensing and gene regulation using engineered transcriptional regulators2011
- Author(s)
  T.Yamazaki, A. Mikami, K. Sode, A. Taniguchi, N. Hanagata
- Organizer
  Japan-China International Forum ofAdvanced Research on Biotechnology
- Place of Presentation
  東京海洋大学品川キャンパス(東京)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-23700545
[Presentation] Engineered transcriptional regulators2011
- Author(s)
  T.Yamazaki, A. Mikami,　K. Sode , A. Taniguchi,　N. Hanagata
- Organizer
  Japan-China International Forum of Advanced Research on Biotechnology
- Place of Presentation
  東京海洋大学　品川キャンパス(東京)
- Data Source
  KAKENHI-PROJECT-23700545
[Presentation] Development of novel designed transcriptional regulators for the universal cell-sensing system2009
- Author(s)
  A.Sakaguchi-Mikami, A.Taniguchi, T.Yamazaki
- Organizer
  22nd European conference on Biomaterials
- Place of Presentation
  ローザンヌ(スイス)
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] 転写調節因子の設計による細胞内センシング技術の開発2009
- Author(s)
  坂口あかね、谷口彰良、山崎智彦
- Organizer
  日本バイオマテリアル学会
- Place of Presentation
  京都
- Year and Date
  2009-11-16
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] The universal cell-based sensing system utilizing designed transcriptional regulators2009
- Author(s)
  T.Yamazaki, A.Taniguchi, A.Sakaguchi-Mikami
- Organizer
  International Conference on Quality Control of Biomaterials and Tissue Engineering Products
- Place of Presentation
  天津(中国)(招待講演)
- Year and Date
  2009-09-28
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] 人工転写調節因子を用いた遺伝子発現技術の開発2009
- Author(s)
  坂口あかね, 山崎智彦、谷口彰良
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] Building a novel transcriptional regulator as a universal switch platform2009
- Author(s)
  T.Yamazaki, A.Mikami, A.Taniguchi
- Organizer
  MANA International Symposium 2009
- Place of Presentation
  つくば(日本)
- Year and Date
  2009-02-27
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] The universal cell-based sensing system utilizing designed transcriptional regulators2009
- Author(s)
  山崎智彦、谷口彰良、坂口あかね
- Organizer
  International Conference on Quality Control of Biomaterials and Tissue Engineering Products
- Place of Presentation
  天津、中国
- Year and Date
  2009-09-29
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] Protein Engineering Approaches to Molecular Recognition Element Constructi on for Biosensor Application2009
- Author(s)
  山崎智彦, 坂口あかね
- Organizer
  Nanotech Indonesia
- Place of Presentation
  Jakarta, Indonesia
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] 人工転写調節因子を用いた遺伝子発現制御技術の開発2009
- Author(s)
  坂口あかね、山崎智彦、谷口彰良
- Organizer
  農芸化学会
- Place of Presentation
  福岡
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] Protein Engineering Approaches to Molecular Recognition Element Constructi on for Biosensor Application2009
- Author(s)
  T.Yamazaki, A.Sakaguchi-Mikami
- Organizer
  Nanotech Indonesia
- Place of Presentation
  ジャカルタ(インドネシア)(招待講演)
- Year and Date
  2009-11-11
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] Towards the development of the universal mammalian cell-sensing system utilizing bacterial periplasmic binding proteins2008
- Author(s)
  A. Mikami, T. Yamazaki, K. Sode, A. Taniguchi
- Organizer
  10th conference on Biosensors 2008
- Place of Presentation
  上海(中国)
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] 基質結合タンパク質を用いた新規転写調節因子の開発2008
- Author(s)
  坂口あかね、山崎智彦、奥田順子、早出広司、谷口彰良
- Organizer
  分子生物学会,日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] Design and Construction of Novel Engineered Transcriptional Regulators2008
- Author(s)
  T.Yamazaki, A.Mikami, A.Taniguchi
- Organizer
  The 5th Sweden-Japan Bio-Nano Workshop
- Place of Presentation
  ストックホルム(スウェーデン)
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] Towards the development of the universal mammalian cell-sensing system utilizing bacterial substrate binding proteins2008
- Author(s)
  A. Mikami, T. Yamazaki, A. Taniguchi
- Organizer
  Japan-Korea Joint Symposium 2008 On Biomaterials and Regenerative Medicine
- Place of Presentation
  つくば(日本)
- Year and Date
  2008-08-21
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] the development of the universal mammalian cell-sensing system utilizing bacterial periplasmic binding proteins2008
- Author(s)
  A.Sakaguhi-Mikami, T.Yamazaki, K.Sode, A.Taniguchi
- Organizer
  Biosensors 2008
- Place of Presentation
  上海(中国)
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] 基質結合タンパク質を用いた新規転写調節因子の開発2008
- Author(s)
  坂口あかね, 山崎智彦、奥田順子、早出広司、谷口彰良
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20700389
[Presentation] Towards the development of the universal mammalian cell-sensing system utilizing bacterial substrate binding proteins2008
- Author(s)
  A.Sakaguhi-Mikami, T.Yamazaki, K.Sode, A.Taniguchi
- Organizer
  Japan-Korea Joint Symposium 2008 on Biomaterials and Regenerative Medicine
- Place of Presentation
  つくば
- Year and Date
  2008-08-21
- Data Source
  KAKENHI-PROJECT-20700389

1. 山崎智彦 (50419264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAKAGUCHI-MIKAMI Akane 三上 あかね

三上 あかね ミカミ アカネ

坂口あかね

MIKAMI (SAKAGUCHI) Akane 三上 あかね

三上 あかね(坂口あかね) ミカミ アカネ

MIKAMI Akane 三上 あかね

SAKAGUCHI Akane 坂口 あかね

Research Projects

Research Products

Co-Researchers

Development of intracellular multi-monitoring system and its application for analysis of glycation effect on tumor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of monitoring system for intracelular reactive carbon spices-related glycationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of intracellular glycated products monitoring systems for cellular functional regulation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Design of novel transcriptional regulators for the development of an intracellular sensing and functional regulation platform in mammalian cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 『バイオセンサーのはなし』第3章11節’センサー細胞を用いた毒性評価’2012

Author(s)

Publisher

Data Source

[Journal Article] Advancing the development of glycated protein biosensing technology: next-generation sensing molecules2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ヘモグロビンA1cのPOCT測定法の現状と展望2015

Author(s)

Journal Title

Data Source

[Journal Article] Identification and functional analysis of fructosyl amino acid-binding protein from Gram-positive bacterium Arthrobacter sp2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cloning and Characterization of Fructosamine-6-Kinase from Arthrobacter aurescens2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Construction of a novel glucose-sensing molecule based on a substrate-binding protein for intracellularsensing2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protein Engineering Approaches to Novel Glucose Sensing Elements Construction2010

Author(s)

Journal Title

Data Source

[Journal Article] The Construction of a Glucose Sensing Luciferase2009

Author(s)

Journal Title

Data Source

[Journal Article] Construction of a novel transcriptional regulator based on a substrate binding protein : a probe for intracellular sensing and gene regulation systems2009

Author(s)

Journal Title

Data Source

[Journal Article] 細菌由来基質結合タンパク質を用いた人工転写調節因子の設計2009

Author(s)

Journal Title

Data Source

[Journal Article] Glucose sensing luciferase2009

Author(s)

SAKAGUCHI-MIKAMI Akane 三上あかね

三上あかねミカミアカネ

MIKAMI (SAKAGUCHI) Akane 三上あかね

三上あかね(坂口あかね) ミカミアカネ

MIKAMI Akane 三上あかね

SAKAGUCHI Akane 坂口あかね

[Presentation] 新規糖化物応答転写調節因子に基づく細胞内糖化物モニタリング法の開発2017