Yamaguchi Tamio 山口太美雄

… Alternative Names

山口太美雄ヤマグチタミオ

YAMAGUCHI Tamio 山口太美雄

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Researcher Number	70536292
Other IDs
Affiliation (Current)	2025: 鈴鹿医療科学大学, 保健衛生学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 鈴鹿医療科学大学, 保健衛生学部, 教授 2012: 藤田保健衛生大学, 疾患モデル教育研究センター, 研究生 2010: 藤田保健衛生大学, 疾患モデル教育研究センター, 研究生
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Basic Section 49030:Experimental pathology-related / Experimental pathology
Keywords	Principal Investigator 糖尿病性腎臓病 / 同一カロリー摂取 / PFCバランス / 動物モデル / 慢性腎臓病 / 糖尿病 / 認知機能障害 / 糖尿病性腎症 / 脳由来神経栄養因子（BDNF） / 海馬 … More / ミクログリア / 大脳皮質 / 腎機能障害 / 血圧 / 肥満2型糖尿病モデル / SDT fattyラット … More Except Principal Investigator 細胞増殖 / 多発性嚢胞腎 / 酸化ストレス / リン酸化プロテオミクス / 情報伝達経路 / オミックス解析 / PKD / CKD / シグナル伝達 / 多発性嚢胞腎症 / 食塩感受性高血圧 / 慢性腎臓病 / S6 / polycystic liver / polycystic kidney / 細胞内情報伝達 / 嚢胞 / 線維化 / 核内受容体 / 線維 / SCD1 / TGF / mTOR / ERK / PPAR Less

摂取カロリー同等/PFCバランス不同食の糖尿病性腎臓病と認知機能障害に及ぼす影響Principal Investigator
- Principal Investigator
  
  山口太美雄
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Suzuka University of Medical Science
Research on the key factors and signal transduction cascades of the onset of chronic kidney disease (CKD): Application of global omics technologies.
- Principal Investigator
  
  NAGAO Shizuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Fujita Health University
A novel therapeutic approach for cystic disease:Inhibition of intracellular signal transduction pathways by a nuclear receptor cascade
- Principal Investigator
  
  SHIZUKO Nagao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Fujita Health University

All 2020 2019 2018 2013 2012 2011 2010

All Journal Article Presentation Book

[Book] Annual Review 2013腎臓2013
- Author(s)
  長尾静子、釘田雅則、吉原大輔、山口太美雄　（分担）
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease2019
- Author(s)
  Kikuchi Koichi、Saigusa Daisuke、Kanemitsu Yoshitomi、Matsumoto Yotaro、Tsukamoto Hiroki、Abe Takaaki
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1835-1835
- DOI
  10.1038/s41467-019-09735-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06651, KAKENHI-PROJECT-18K06742, KAKENHI-PROJECT-18K07076, KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-18K08199, KAKENHI-PLANNED-17H06394, KAKENHI-PUBLICLY-18H04805, KAKENHI-PROJECT-19H03557, KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-17K00856
[Journal Article] Increased salt intake does not worsen the progression of renal cystic disease in high water-loaded PCK rats.2019
- Author(s)
  Shizuko Nagao, Masanori Kugita, Kanako Kumamoto, Aya Yoshimura, Kazuhiro Nishii, Tamio Yamaguchi.
- Journal Title
  
  PLoS One.
  
  Volume: 14(3) Issue: 3 Pages: e0207461-e0207461
- DOI
  10.1371/journal.pone.0207461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07076, KAKENHI-PROJECT-18K11141
[Journal Article] 多発性嚢胞腎発症のメカニズム2013
- Author(s)
  長尾静子、釘田雅則、吉原大輔、山口太美雄
- Journal Title
  
  Annual Review 2013 腎臓 (冨野康日己、柏原直樹、成田一衛編、中外医学社、東京)
  
  Pages: 101-108
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] PPARγ agonists in polycystic kidney disease with frequent development of cardiovascular disorders.2012
- Author(s)
  Shizuko Nagao, Yamaguchi T.
- Journal Title
  
  Current Molecular Pharmacology
  
  Volume: Vol.5, No.2 Pages: 292-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] PPAR-γ agonistsin polycystic kidney disease with frequent development of cardiovascular disorders2012
- Author(s)
  Nagao S, Yamaguchi T
- Journal Title
  
  Curr MolPharmacol
  
  Volume: 5(2) Pages: 292-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Global gene expression profiling in PPAR-γ agonist-treated kidneys in an orthologous rat model of human autosomal recessive polycystic kidney disease2012
- Author(s)
  Yoshihara D, Kugita M, Yamaguchi T, Aukema H.M., Kurahashi H., Morita M., Hiki Y., Calvet J.P., Wallace D.P., Toyohara T., TAbe T., Nagao S.
- Journal Title
  
  PPAR Research
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Animal models for human polycystic kidney disease.2012
- Author(s)
  Shizuko Nagao, Kugita M, Yoshihara D, Yamaguchi T.
- Journal Title
  
  Experimental Animal
  
  Volume: Vol.61, No.5 Pages: 477-488
- NAID
  10031121852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Global Gene ExpressionProfiling in PPAR-γ Agonist-TreatedKidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease.2012
- Author(s)
  Yoshihara D, Kugita M, Yamaguchi T, Aukema HM, Kurahashi H, Morita M, Hiki Y, Calvet JP, Wallace DP, Toyohara T, Abe T, Nagao S.
- Journal Title
  
  PPAR Res
  
  Volume: 2012 Pages: 695898-695898
- DOI
  10.1155/2012/695898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351, KAKENHI-PUBLICLY-23013019, KAKENHI-PROJECT-23659182, KAKENHI-PROJECT-24390085, KAKENHI-PROJECT-24790393
[Journal Article] Animal models for human polycystic kidney disease2012
- Author(s)
  Nagao S, Kugita M, Yoshihara D, Yamaguchi T
- Journal Title
  
  Exp Anim.
  
  Volume: 61(5) Pages: 477-88
- NAID
  10031121852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Global gene expression profiling in early-stage polycystic kidney disease in the Han : SPRD Cy rat identifies a role for RXR signaling.2011
- Author(s)
  Kugita M., Nishii K., Morita M., Yoshihara D., Kowa-Sugiyama H., Yamada K., Yamaguchi T., Wallace D.P., Calvet J.P., Kurahashi H., Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 300(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] PPAR-{gamma} agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011
- Author(s)
  Yoshihara D, Kurahashi H, Morita M,Kugita M, Hiki Y, Aukema HM, Yamaguchi T, Calvet JP, Wallace DP, Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 300(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] PPAR-{gamma} agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011
- Author(s)
  Yoshihara D., Kurahashi H., Morita M., Kugita M., Hiki Y., Aukema HM., Yamaguchi T., Calvet JP., Wallace DP., Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 300(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Global gene expression profiling in early-stage polycystic kidney disease in the Han : SPRD Cy rat identifies a role for RXR signaling.2011
- Author(s)
  Kugita M, Nishii K, Morita M, Yoshihara D, Kowa-Sugiyama H, Yamada K, Yamaguchi T, Wallace DP, Calvet JP, Kurahashi H, Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 300(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Polycystic kidney disease in Han : SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin.2010
- Author(s)
  Nagao S, Morita M, Kugita M, Yoshihara D, Yamaguchi T, Kurahashi H, Calvet JP, Wallace DP.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 299(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Polycystic kidney disease in Han : SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin.2010
- Author(s)
  Nagao S, Morita M, Kugita M, Yoshihara D, Yamaguchi T, Kurahashi H, Calvet JP, Wallace DP.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 同一摂取カロリーでラードとスクロースの比率を高めた場合の非肥満糖尿病マウスの血糖動態と腎傷害発現2020
- Author(s)
  吉村文, 山口太美雄, 釘田雅則, 熊本海生航, 塩竈和也, 荻津直通, 三浦俊宏, 米田操, 長村洋一, 長尾静子
- Organizer
  第63回日本腎臓学会学術総会、横浜、2020年8月19日～21日、パシフィコ横浜　アネックスホール
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Long-term effect of novel morphometric 3D capsule device to constrain growth in polycystic kidney: comparison between wild-type, Cy/+ and PCK rat models.2020
- Author(s)
  Kyongtae T. Bae, Aya Yoshimura, Kanako Kumamoto, Masanori Kugita, Tamio Yamaguchi, Shigeo Horie, Junu Bae, Shizuko Nagao
- Organizer
  Kidney week, 2020, Denver, U.S.A., 2020 Oct 19-25.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Comparison of the effect of calorie matched high saturated-fat and high unsaturated-fat diets on lysosomal renal injury in non-obese, streptozotocin-injected CD-1 mice.2020
- Author(s)
  Tamio Yamaguchi, Aya Yoshimura, Masanori Kugita, Kanako Kumamoto, Kazuya Shiogama, Kyongtae T. Bae, Shizuko Nagao
- Organizer
  Kidney week, 2020, Denver, U.S.A., 2020 Oct 19-25.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Development and implantation of novel morphometric 3D capsule device to constrain structural change of polycystic kidney: a feasibility study in a rat model.2019
- Author(s)
  Kyongtae T. Bae#, Kanako Kumamoto#, Aya Yoshimura#, Masanori Kugita, Shigeo Horie, Tamio Yamaguchi, Junu T. Bae, Shizuko Nagao (# equal author)
- Organizer
  Kidney week, 2019, Washington, DC, U.S.A., Nov 5-10.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Comparison study of calorie matched high fat and high sugar diets on renal injury with lysosomal dysfunction in pre-diabetic mice.2019
- Author(s)
  Aya Yoshimura#, Tamio Yamaguchi#, Masanori Kugita#, Kanako Kumamoto, Kazuya Shiogama, Naomichi Ogitsu, Toshihiro Miura, Misao Yoneda, Yoichi Nagamura, Shizuko Nagao (# equal author)
- Organizer
  Kidney week, 2019, Washington, DC, U.S.A., Nov 5-10.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 多発性嚢胞腎症モデルPCKラットの腎臓におけるメタボローム解析―グルコース代謝経路についてー2018
- Author(s)
  釘田雅則、熊本海生航、吉村　文、山口太美雄、長尾静子
- Organizer
  第65回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Glucose metabolic profiles in renal tissue of an orthologous PCK rat model of human PKD using metabolic and proteomic analyses.2018
- Author(s)
  Shizuko Nagao, Masanori Kugita, Kanako Kumamoto, Aya Yoshimura, Tamio Yamaguchi, Kazuki Nakajima, Kazuo Takahashi, Yukio Yuzawa
- Organizer
  Kidney week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 多発性嚢胞腎の動物モデル2013
- Author(s)
  長尾静子 (枝澄香)、釘田雅則、吉原大輔、山口多美雄
- Organizer
  第60回日本実験動物学会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Ameliorative effect of telmisartan on fibrocystic liver disease progression in an orthologous rat model of human autosomal recessive polycystic kidney disease (ARPKD)2013
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Mai Sasaki, Shigeo Horie, Koichi Nakanishi, Takaaki Abe, Harold M. Aukema, Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] テルミサルタンによるヒト常染色体劣性多発性嚢胞腎症オーソログ遺伝子変異モデルにおける病態発現抑制効果2013
- Author(s)
  長尾静子(枝澄香)、吉原大輔、釘田雅則、佐々木麻衣、堀江重郎、中西浩一、阿部高明、山口太美雄
- Organizer
  第48回日本小児腎臓学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Ameliorative effect of telmisartan on fibrocystic liver disease progression in an orthologous rat model of human autosomal recessive polycystic kidney disease (ARPKD).2013
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Mai Sasaki, Shigeo Horie, Koichi Nakanishi, Takaaki Abe, Harold M. Aukema, Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  World Congress of Nephrology2013
- Place of Presentation
  HongKong, China
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎の動物モデル.2013
- Author(s)
  長尾静子(枝澄香)、釘田雅則、吉原大輔、山口太美雄
- Organizer
  第60回日本実験動物学会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ラット多発性嚢胞腎におけるPPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング2012
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾静子 (枝澄香)
- Organizer
  第55回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ラット多発性嚢胞腎における PPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング.2012
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾静子(枝澄香)
- Organizer
  第55回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットPCKにおけるテルミサルタンの病態発現抑制効果2012
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、長尾静子 (枝澄香)
- Organizer
  第20回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるretinoid X receptor (RXR)の発現と局在2012
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾静子 (枝澄香)
- Organizer
  日本実験動物科学・技術九州2012
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデル動物の腎臓における retinoid X receptor (RXR)の発現と局在2012
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾静子(枝澄香)
- Organizer
  日本実験動物科学・技術九州 2012
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Telmisartan ameliorates fibrocystic liver disease in PCK rats, an orthologous model of human ARPKD2012
- Author(s)
  Masanori Kugita, Daisuke Yoshihara, Shigeo Horie, Harold M Aukema, Tamio Yamaguchi, Shizuko Nagao
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞性疾患におけるPPARγ部分作動薬の治療効果2012
- Author(s)
  吉原大輔, 釘田雅則, 山口太美雄, 長尾静子 (枝澄香)
- Organizer
  第44回藤田医学会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Telmisartan Ameliorates Fibrocystic Liver Disease in an Orthologous Rat Model of Human ARPKD2012
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Shigeo Horie, Harold M. Aukema,Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  American Society of Nephrology Kidney Week 2012
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Telmisartan ameliorates fibrocystic liver disease in PCK rats, an orthologous model ofhuman ARPKD.2012
- Author(s)
  Masanori Kugita, Daisuke Yoshihara,Shigeo Horie, Harold M Aukema, Tamio Yamaguchi, Shizuko Nagao
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞性疾患における PPARγ部分作動薬の治療効果2012
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、長尾静子(枝澄香)
- Organizer
  第44回藤田医学会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラット PCKにおけるテルミサルタンの病態発現抑制効果.2012
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、長尾静子(枝澄香)
- Organizer
  第20回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2012-09-16
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 網羅的遺伝子発現解析を用いた多発性嚢胞腎ラットPCKにおけるPPARγアゴニストによる治療機序の検証2011
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾枝澄香(静子)
- Organizer
  第19回嚢胞性腎疾患研究会
- Place of Presentation
  東京、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PPAE-γ agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011
- Author(s)
  Daisuke Yoshihara., Hiroki Kurahashi., Miwa Morita., Masanori Kugita., Yoshiyuki Hiki., Harold M.Aukema., Tamio Yamaguchi., James P.Calvet, Darren P.Wallace., Shizuko Nagao.
- Organizer
  World Congress of Nephrology 2011
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] RXR は嚢胞形成機序における共通の因子か?2011
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Global gene expression profiling in kidneys of PPAR-γ agonist-treated PCK rats, an orthologous model of human ARPKD.2011
- Author(s)
  Yoshihara D, Kugita M, Kurahashi H, Morita M, Hiki Y, Yamaguchi T, Aukema HM, Wallace DP, Calvet JP, Toyohara T, Abe T, Nagao S.
- Organizer
  American Society of Nephrology 44th Annual Meeting & Scientific Exposition 2011
- Place of Presentation
  Philadelphia, PA USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラット PCK の腎臓における PPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング2011
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、倉橋浩樹、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] RXRは嚢胞形成機序における共通の因子か?2011
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデルであるjckマウスの特徴2011
- Author(s)
  長尾枝澄香(静子)、吉原大輔、釘田雅則、森田美和、山口太美雄、Wallace Darren
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Global gene expression profiling in kidneys of PPAR-gamma agonist-treated PCK rats, an orthologous model of human ARPKD2011
- Author(s)
  Yoshihara D., Kugita M., Kurahashi H, Morita M, Hiki Y, Yamaguchi T, Aukema HM, Wallace DP, Calvet JP, Toyohara T., Abe T., Nagao S.
- Organizer
  American Society of Nephrology 44th Annual Meeting & Scientific Exposition
- Place of Presentation
  Philadelphia, PA USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Wallace Darren 多発性嚢胞腎症モデルであるj ckマウスの特徴.2011
- Author(s)
  長尾枝澄香(静子)、吉原大輔、釘田雅則、森田美和、山口太美雄
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットPCKの腎臓におけるPPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング2011
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、倉橋浩樹、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 羅的遺伝子発現解析を用いた多発性嚢胞腎ラット PCK における PPAR-γアゴニストによる治療機序の検証2011
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾枝澄香(静子)
- Organizer
  第19回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒト多発性嚢胞腎症のラットモデルにおけるPPAE-γアゴニストの治療効果2011
- Author(s)
  吉原大輔、倉橋浩樹、森田美和、釘田雅則、比企能之、Aukema Harold、山口太美雄、Calvet James、Wallace Darren、長尾枝澄香(静子)
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PPAR-γagonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease.2011
- Author(s)
  Daisuke Yoshihara, Hiroki Kurahashi, M iwa Morita, Masano r i K ugit a, Yoshiyuki Hiki, Harold M Aukema, Tamio Yamaguchi, James P Calvet, Darren PWallace, Shizuko Nagao.
- Organizer
  World Congress of Nephrology 2011
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒト多発性嚢胞腎症のラットモデルにおける PPAR-γアゴニストの治療効果2011
- Author(s)
  吉原大輔、倉橋浩樹、森田美和、釘田雅則、比企能之、Aukema Harold、山口太美雄、Calvet James、Wallace Darren、長尾枝澄香(静子)
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PCKラットの腎臓と肝臓におけるPPAR-γアゴニストの治療効果2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第18回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2010-10-31
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 嚢胞性腎臓疾患モデルCyラットにおける嚢胞形成とRXRとの関連性についての検討2010
- Author(s)
  釘田雅則、西井一宏、森田美和、吉原大輔、山口太美雄、日下守、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Thiazolidinedione Ameliorates Autosomal Recessive Polycystic Kidney and Liver Disease in the PCK Rat, an Orthologous Model of Human ARPKD.2010
- Author(s)
  Yoshihara D., Kurahashi H., Morita M., Kugita M., Hiki Y., Aukema H.M., Yamaguchi T., Calvet J.P., Wallace D.P., Nagao S.
- Organizer
  American Society of Nephrology 43rd Annual Meeting & Scientific Exposition
- Place of Presentation
  Denver, CO USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 嚢胞性腎臓疾患モデル Cy ラットにおける嚢胞形成と RXR との関連性についての検討.2010
- Author(s)
  釘田雅則、西井一宏、森田美和、吉原大輔、山口太美雄、日下守、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PCK ラットの腎臓と肝臓における PPAR-γアゴニストの治療効果2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第18回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2010-10-31
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒトARPKDとオーソログな遺伝子変異モデルであるPCKラットの腎・肝組織における情報伝達系の検討2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、倉橋浩樹、山口太美雄、長尾静子
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Thiazolidinedione Ameliorates Autosomal Recessive Polycystic Kidney and Liver Disease in the PCK Rat, an Orthologous Model of Human ARPKD.2010
- Author(s)
  Yoshihara D, Kurahashi H, Morita M, Kugita M, Hiki Y, Aukema HM, Yamaguchi T, Calvet JP, Wallace DP, Nagao S.
- Organizer
  American Society of Nephrology 43rd Annual Meeting & Scientific Exposition.
- Place of Presentation
  Denver, CO USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒト ARPKDとオーソログな遺伝子変異モデルである PCK ラットの腎・肝組織における情報伝達系の検討.2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、倉橋浩樹、山口太美雄、長尾静子
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットモデル PCK の腎臓と肝臓における細胞情報伝達系の解析.2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットモデルPCKの腎臓と肝臓における細胞情報伝達系の解析2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351

1. SHIZUKO Nagao (20183527)

# of Collaborated Projects: 3 results

# of Collaborated Products: 62 results
2. MASANORI Kugita (50440681)

# of Collaborated Projects: 2 results

# of Collaborated Products: 59 results
3. YOSHIHARA Daisuke (70454402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 52 results
4. MORITA Miwa (90329699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
5. YAGYU Shigeru (10200479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIKI Yoshiyuki (20156566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
7. KURAHASHI Hiroki (30243215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
8. 吉村文 (90466483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 塚本宏樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamaguchi Tamio 山口 太美雄

山口 太美雄 ヤマグチ タミオ

YAMAGUCHI Tamio 山口 太美雄

Research Projects

Research Products

Co-Researchers

摂取カロリー同等/PFCバランス不同食の糖尿病性腎臓病と認知機能障害に及ぼす影響Principal Investigator

Principal Investigator

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Review Section

Research Institution

Research on the key factors and signal transduction cascades of the onset of chronic kidney disease (CKD): Application of global omics technologies.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel therapeutic approach for cystic disease:Inhibition of intracellular signal transduction pathways by a nuclear receptor cascade

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Research Institution

[Book] Annual Review 2013腎臓2013

Author(s)

Publisher

Data Source

[Journal Article] Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease2019

Author(s)

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DOI

Data Source

[Journal Article] Increased salt intake does not worsen the progression of renal cystic disease in high water-loaded PCK rats.2019

Author(s)

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DOI

Data Source

[Journal Article] 多発性嚢胞腎発症のメカニズム2013

Author(s)

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[Journal Article] PPARγ agonists in polycystic kidney disease with frequent development of cardiovascular disorders.2012

Author(s)

Journal Title

Data Source

[Journal Article] PPAR-γ agonistsin polycystic kidney disease with frequent development of cardiovascular disorders2012

Author(s)

Journal Title

Data Source

[Journal Article] Global gene expression profiling in PPAR-γ agonist-treated kidneys in an orthologous rat model of human autosomal recessive polycystic kidney disease2012

Author(s)

Journal Title

Data Source

[Journal Article] Animal models for human polycystic kidney disease.2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Global Gene ExpressionProfiling in PPAR-γ Agonist-TreatedKidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Animal models for human polycystic kidney disease2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Global gene expression profiling in early-stage polycystic kidney disease in the Han : SPRD Cy rat identifies a role for RXR signaling.2011

Author(s)

Journal Title

Data Source

[Journal Article] PPAR-{gamma} agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011

Author(s)

Journal Title

Data Source

[Journal Article] PPAR-{gamma} agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011

Author(s)

Journal Title

Yamaguchi Tamio 山口太美雄

山口太美雄ヤマグチタミオ

YAMAGUCHI Tamio 山口太美雄