SAKURAI Yuki 櫻井幸

Researcher Number	70547455
Affiliation (based on the past Project Information) *help	2014 – 2015: 東京医科歯科大学, 医学部附属病院, 医員 2010 – 2012: 東京医科歯科大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 自然免疫 / ウイルス肝炎 / IFN応答性 / 宿主・ウイルス相互作用 / pathway解析 / 包括的解析 / C型肝炎ウイルス Except Principal Investigator RNAポリメラーゼ / 細胞障害効果 / プラークアッセイ / HCV-JFH1培養系

新規インターフェロンλ４遺伝子が関わるウイルス肝炎治療抵抗性機序の解明Principal Investigator
- Principal Investigator
  
  櫻井幸
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Comprehensive analysis on genes and molecular pathways in host cells associated with Hepatitis C virus infection using next-generation sequencing technologyPrincipal Investigator
- Principal Investigator
  
  SAKURAI Yuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
細胞障害性HCV培養系を用いた重症C型肝炎発症機構の解析
- Principal Investigator
  
  筬島裕子
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University

All 2016 2015 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features.2016
- Author(s)
  Kawai-Kitahata F, Asahina Y, Tanaka S, Kakinuma S, Murakawa M, Sayuri Nitta S, Watanabe T, Otani S, Taniguchi M, Goto F, Nagata H, Kaneko S, Tasaka-Fujita M, Nishimura-Sakurai Y, Azuma S, Itsui Y, Nakagawa M, Tanabe M, Takano S, Fukasawa M, Sakamoto M, Maekawa S, Enomoto N, Watanabe M.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 51 Issue: 5 Pages: 473-486
- DOI
  10.1007/s00535-015-1126-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-26460986, KAKENHI-PROJECT-26670380, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16H05285, KAKENHI-PROJECT-16K09345, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-15K19316, KAKENHI-PROJECT-15K08988, KAKENHI-PROJECT-15K08989, KAKENHI-PROJECT-15K08995
[Journal Article] Efficacy of additional radiofrequency ablation after transcatheter arterial chemoembolization for intermediate hepatocellular carcinoma.2016
- Author(s)
  Azuma S, Asahina Y, Nishimura-Sakurai Y, Kakinuma S, Kaneko S, Nagata H, Goto F, Ootani S, Kawai-Kitahata F, Taniguchi M, Murakawa M, Watanabe T, Tasaka-Fujita M, Itsui Y, Nakagawa M, Watanabe M.
- Journal Title
  
  Heptol Res
  
  Volume: 46 Issue: 4 Pages: 312-9
- DOI
  10.1111/hepr.12566
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08988, KAKENHI-PROJECT-26460986, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-15K08989, KAKENHI-PROJECT-16H05285, KAKENHI-PROJECT-16K09345, KAKENHI-PROJECT-15K15285
[Journal Article] Evaluation of IFN resistance in newly established genotype 1b HCV cell culture system.2016
- Author(s)
  Taniguchi M, Tasaka-Fujita M, Nakagawa M, Watanabe T, Kawai-Kitahata F, Otani S, Goto F, Nagata H, Kaneko S, Nitta S, Murakawa M, Nishimura-Sakurai Y, Azuma S, Itsui Y, Mori K, Yagi S, Kakinuma S, Asahina Y, Watanabe M.
- Journal Title
  
  J Clin Transl Hepatol
  
  Volume: 4 Issue: 1 Pages: 5-11
- DOI
  10.14218/jcth.2015.00047
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08988, KAKENHI-PROJECT-26460986, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-15K08989, KAKENHI-PROJECT-16H05285, KAKENHI-PROJECT-26460987, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-15K19316
[Journal Article] Impaired induction of IL28B and expression of IFNλ4 associated with non-response to interferon-based therapy in chronic hepatitis C.2015
- Author(s)
  Murakawa M, Asahina Y, Nakagawa M, Sakamoto N, Nitta S, Kusano-Kitazume A, Watanabe T, Kawai-Kitahata F, Otani S, Taniguchi M, Goto F, Nishimura-Sakurai Y, Itsui Y, Azuma S, Kakinuma S, Watanabe M
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 印刷中 Issue: 6 Pages: 1075-84
- DOI
  10.1111/jgh.12902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590958, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-25670366, KAKENHI-PROJECT-26460986, KAKENHI-PROJECT-26460987, KAKENHI-PROJECT-26460988, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-15K08988, KAKENHI-PROJECT-15K19316, KAKENHI-PROJECT-15K08989
[Journal Article] 多血性肝細胞癌の検出能に関するGd-EOB-DTPA造影MRIとCTAP/CTHAとの比較検討2013
- Author(s)
  東正新、櫻井幸、他
- Journal Title
  
  医学と薬学
  
  Volume: 69 Pages: 64-66
- Data Source
  KAKENHI-PROJECT-23790778
[Journal Article] Association of ITPA gene variant and serum ribavirin concentration with blood cells decline in pegylated interferon-alfa plus ribavirin therapy for chronic hepatitis C.2013
- Author(s)
  Nakagawa M, Sakamoto N, Watanabe T, Nishimura-Sakurai Y, Onozuka I, Azuma S, Kakinuma S, Nitta S, Kiyohashi K,Kusano-Kitazume A, Murakawa M, Yoshino K, Itsui Y, Tanaka Y, Mizokami M,Watanabe M, Ochanomizu Liver Conference Study Group
- Journal Title
  
  Hepatol Int
  
  Volume: 7(1) Issue: 1 Pages: 153-161
- DOI
  10.1007/s12072-012-9363-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790778, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590958
[Journal Article] 多血性肝細胞癌の検出能に関するGd-EOB-DTPA造影MRIとCTAP/CTHAとの比較検討2013
- Author(s)
  東正新,朝比奈靖浩,櫻井幸,吉野耕平,幾世橋佳,新田沙由梨,北詰晶子,村川美也子,中川美奈,柿沼晴,渡辺守
- Journal Title
  
  医学と薬学
  
  Volume: 69巻1号 Pages: 64-66
- Data Source
  KAKENHI-PROJECT-23790778
[Journal Article] Association of ITPA gene variant and serum ribavirin concentration with blood cells decline in pegylated interferon-alfa plus ribavirin therapy for chronic hepatitis C2013
- Author(s)
  Nakagawa M, Nishimura-Sakurai Y, et al.
- Journal Title
  
  Hepatol Int
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790778
[Journal Article] Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immunity2013
- Author(s)
  Nitta S, Sakamoto N, Nakagawa M, Kakinuma S, Mishima K, Kusano-kitazume A, Kiyohashi K, Murakawa M, Nishimura-Sakurai Y, Azuma S, Tasaka-Fujita M, asahina Y, Yoneyama M, Fujita T, Watanabe M
- Journal Title
  
  Hepatology
  
  Volume: 57 Issue: 1 Pages: 46-58
- DOI
  10.1002/hep.26017
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20112009, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-23390108, KAKENHI-PROJECT-23790778, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590958, KAKENHI-PROJECT-24590959, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-24890058, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-25670366, KAKENHI-PROJECT-25860522
[Journal Article] Identification of novel N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication2012
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Okuno Y, Sekine-Osajima Y, Nakagawa M, Kakinuma S, Kiyonashi K, Nitta S, Murakawa M, Azuma S, Nishimura-Sakurai Y, Hagiwara M, Watanabe M
- Journal Title
  
  Antimicrob Agent Chemother
  
  Volume: 56(3) Issue: 3 Pages: 1315-23
- DOI
  10.1128/aac.05764-11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-23790778, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590959, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-21249013
[Journal Article] HCV-NS4B蛋白とIFN発現系シグナル分子との分子間相互作用の解析2012
- Author(s)
  新田沙由梨,坂本直哉,藤田めぐみ,柿沼晴,村川美也子,北詰晶子,幾世橋佳,船岡祐介,渡辺貴子,植山真由美,小野塚泉,櫻井幸,中川美奈,東正新,渡辺守
- Journal Title
  
  消化器と免疫
  
  Volume: 48号 Pages: 174-177
- Data Source
  KAKENHI-PROJECT-23790778
[Journal Article] The Japan Non-B, Non-C Liver Cirrhosis Study Group. Survey of non-B, non-C liver cirrhosis in Japan.2012
- Author(s)
  Suzuki Y
- Journal Title
  
  Hepatol Res.
  
  Volume: - Issue: 10 Pages: 1020-1031
- DOI
  10.1111/hepr.12056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659395, KAKENHI-PROJECT-23790778
[Journal Article] HCV-NS4B蛋白とIFN発現系シグナル分子との分子間相互作用の解析2012
- Author(s)
  新田沙由梨、櫻井幸、他
- Journal Title
  
  消化器と免疫
  
  Volume: 48 Pages: 174-177
- Data Source
  KAKENHI-PROJECT-23790778
[Journal Article] Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b2011
- Author(s)
  Sakamoto N, Nakagawa M, Azuma S, Watanabe M, et al.
- Journal Title
  
  J Med Virol
  
  Volume: 83 Issue: 5 Pages: 871-878
- DOI
  10.1002/jmv.22038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590833, KAKENHI-PROJECT-22390151, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22710191, KAKENHI-PROJECT-22790633, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23790778
[Journal Article] Serum interleukin-6 levels correlate with resistance to treatment of chronic hepatitis C infection with pegylated-interferon-α2b plus ribavirin.2011
- Author(s)
  Ueyama M, Nishimura-Sakurai Y, et al.
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Issue: 7 Pages: 1081-91
- DOI
  10.3851/imp1933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790778
[Journal Article] Studies on virus kinetics using infectious fluorescence-tagged hepatitis C virus cell culture2011
- Author(s)
  Yamamoto M, Sakamoto N, Nakamura T, Itsui Y, Nakagawa M, Nishimura-Sakurai Y, Kakinuma S, Azuma S, Kato T, Wakita T, Watanabe M
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Issue: 3 Pages: 258-269
- DOI
  10.1111/j.1872-034x.2010.00771.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22790633, KAKENHI-PROJECT-23790778
[Journal Article] Inhibitory effect of a triterpenoid compound, with or without alpha interferon, on hepatitis C virus infection2011
- Author(s)
  Watanabe T, Sakamoto N, Nakagawa M, Azuma S, Watanabe M, et al.
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 55(6) Issue: 6 Pages: 2537-2545
- DOI
  10.1128/aac.01780-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22790633, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23790778
[Journal Article] Serum interleukin-6 levels correlate with resistance to treatment of chronic hepatitis C infection withpegylated-interferon-α2b plus ribavirin2011
- Author(s)
  Ueyama M, Nakagawa M, Sakamoto N,Onozuka I, Funaoka Y, Watanabe T, Nitta S, Kiyohashi K, Kitazume A, Murakawa M, Nishimura-Sakurai Y, Sekine-Osajima Y, Itsui Y, Azuma S, Kakinuma S, Watanabe M and the Ochanomizu-Liver Conference Study Group
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Issue: 7 Pages: 1081-1091
- DOI
  10.3851/imp1864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-23790778
[Journal Article] Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells.2010
- Author(s)
  Nishimura-Sakurai Y, Sakamoto, N, Sekine-Osaiima Y, et al.
- Journal Title
  
  J.Gastroenterol
  
  Volume: 45 Pages: 523-536
- NAID
  10027216127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590720
[Presentation] Serial changes in M2BPGi levels as predictors of fibrosis and HCC in chronic hepatitis C.2016
- Author(s)
  Nagata H, Sakurai Y, Nakagawa M, Kakinuma S, AzumaS, Murakawa M, Nitta S, Itsui Y, Asahina Y, Watanabe M
- Organizer
  25th conference of the Asian Pacific Association for the Study of the Liver (APASL 2016)
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460986
[Presentation] 肝細胞癌の病態に関連するTERT遺伝子とB型肝炎ウイルスX蛋白の機能解析2015
- Author(s)
  永田紘子, 朝比奈靖浩, 井津井康浩, 北畑富貴子, 金子俊, 後藤文男, 大谷賢志, 谷口未樹, 村川美也子, 新田沙由梨, 渡辺貴子, 櫻井幸, 中川美奈, 東正新, 柿沼晴, 田中真二, 田邉稔, 榎本信幸, 渡辺守
- Organizer
  JDDW2016
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-26460986
[Presentation] C型慢性肝炎患者におけるIFN治療応答性に関わる肝内ISG発現とIFNλ4の関連2015
- Author(s)
  村川美也子, 朝比奈靖浩, 北畑富貴子, 中川美奈, 永田紘子, 金子俊, 後藤文男, 谷口未樹, 大谷賢志, 新田沙由梨, 渡辺貴子, 櫻井幸, 井津井康浩, 東正新, 柿沼晴, 飯島沙幸, 田中靖人, 坂本直哉, 渡辺守
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460986
[Presentation] 肝細胞癌の病態に関連する宿主ゲノム変異とB型肝炎ウイルスX蛋白の関連解析2015
- Author(s)
  永田紘子, 朝比奈靖浩, 井津井康浩, 北畑富貴子, 金子俊, 後藤文男, 大谷賢志, 谷口未樹, 村川美也子, 新田沙由梨, 渡辺貴子, 櫻井幸, 中川美奈, 東正新, 柿沼晴, 田中真二, 田邉稔, 榎本信幸, 渡辺守
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460986
[Presentation] 炎症性腸疾患コホートにおけるHBV再活性化の実態と再活性化及びde novo B型肝炎に関わる要因の解析2015
- Author(s)
  井津井康浩, 永田紘子, 金子俊, 後藤文男, 大谷賢, 谷口未樹, 北畑富貴子, 村川美也子, 渡辺貴子, 櫻井幸, 中川美奈, 東正新, 柿沼晴, 大岡真也, 朝比奈靖浩, 渡辺守
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460986
[Presentation] インターフェロンλ産生能および抗ウイルス治療効果に関わるIL28B遺伝子多型(SNP)の機能解析2012
- Author(s)
  村川美也子,坂本直哉,中川美奈,吉野耕平,幾世橋佳,北詰晶子,新田沙由梨,渡辺貴子,櫻井幸,東正新,柿沼晴,渡辺守
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Year and Date
  2012-06-08
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] Impaired IL28B gene induction and poor IL28B promoter activity influenced by the IL28B minor allele are closely associated with a null response to interferon in chronic hepatitis C patients2012
- Author(s)
  Asahina Y, Murakawa M, Sakamoto N,Kakinuma S, Nakagawa M, Azuma S, Nishimura-Sakurai Y, Nitta S,Kusano-Kitazume A, Watanabe M
- Organizer
  63rd Annual Meetingof American Association for the Study ofLiver Diseases
- Place of Presentation
  Boston, MA.
- Year and Date
  2012-11-11
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] 抗HCV活性を有するN-(morpholine-4-carbonyloxy)amidine化合物の同定2012
- Author(s)
  北詰晶子,坂本直哉,奥野友紀子,中川美奈,柿沼晴,幾世橋佳,新田沙由梨,村川美也子,東正新,櫻井幸,萩原正敏,渡辺守
- Organizer
  JDDW2012第16回日本肝臓学会大会
- Place of Presentation
  神戸
- Year and Date
  2012-10-10
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] EOB-MRIおよびAngio-CTによる多血性肝細胞癌に関する検討2012
- Author(s)
  東正新,坂本直哉,櫻井幸,吉野耕平,幾世橋佳,新田沙由梨,北詰晶子,村川美也子,中川美奈,柿沼晴,渡辺守
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] 非B非C肝硬変の肝発癌に関連する因子の検討2012
- Author(s)
  櫻井幸,中川美奈,東正新,柿沼晴,坂本直哉,渡辺守
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] Antiviral effetcts and action mechanisms of novel N-(morpholine-4-carbonyloxy) amidine compounds against hepatitis C virus2012
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Okuno Y, Mori, K, Nakagawa, M, Kakinuma S, Nitta S, Murakawa M, Azuma S, Nishimura-Sakurai Y, Matsumoto A, Hagiwara M, Asahina Y, Watanabe M
- Organizer
  63rd Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, MA.
- Year and Date
  2012-11-11
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] Treatment and outcomes for elderly patients with hepatocellular caricinoma2012
- Author(s)
  Azuma S, Sakamoto N, Sakurai Y, Nakagawa M, Kakinuma S, Watanabe M
- Organizer
  The 22nd Conference of the Asian PacificAssociation for the Study of the Liver
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2012-02-18
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] Impaired induction of IL28B expression in PBMC is associatedwith null response to interferon therapy in chronic hepatitis C2012
- Author(s)
  Murakawa M, Sakamoto N, Nakagawa M, Kawai F, Fuziki J, Otani S, Yamanaka H, Kitazume A, Nitta S, Watanabe T,Sakurai Y, Kakinuma S, Asahina Y, Watanabe M
- Organizer
  19th International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Venice,Italy
- Year and Date
  2012-10-08
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] 肝細胞癌におけるEOB-DTPA造影MRIとAngio-CTの比較検討2012
- Author(s)
  東正新,坂本直哉,櫻井幸,吉野耕平,幾世橋佳,新田沙由梨,北詰晶子,村川美也子,中川美奈,柿沼晴,渡辺守
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] 高齢者肝細胞癌患者に対する治療方法とその成績2011
- Author(s)
  東正新,坂本直哉,櫻井幸,吉野耕平,幾世橋佳,新田沙由梨,北詰晶子,村川美也子,中川美奈,柿沼晴,渡辺守
- Organizer
  第15回日本肝臓学会大会
- Place of Presentation
  福岡.
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] ITPA gene variant protects against treatment-induced anemia and improves viral clearance by pegylated interferon-alfa and ribavirin therapy in chronic hepatitis C patients2011
- Author(s)
  Sakamoto N, Tanaka Y, Nakagawa M, Yatsuhashi H, Nishiguchi S, Enomoto N, Azuma S, Nishimura-Sakurai Y, Kakinuma S, Nishida N, Tokunaga K, Mizokami M, Watanabe M
- Organizer
  62nd Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, CA.
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] C型慢性肝炎のPEG-IFNα-2b/Ribavirin併用療法におけるITPA遺伝子の臨床的意義2011
- Author(s)
  櫻井幸、他
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] C型慢性肝炎のPEG-IFNα-2b/Ribavirin併用療法におけるITPA遺伝子の臨床的意義2011
- Author(s)
  櫻井幸,中川美奈,坂本直哉,植山真由美,筬島裕子,東正新,柿沼晴,田中靖人,溝上雅史,渡辺守
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京.
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] 非B非C肝硬変の実態に関する検討2011
- Author(s)
  櫻井幸,中川美奈,坂本直哉
- Organizer
  第15回日本肝臓学会大会
- Place of Presentation
  福岡.
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] 非B非C肝硬変の実態に関する検討2011
- Author(s)
  櫻井幸、中川美奈、坂本直哉
- Organizer
  第15回日本肝臓学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] 非B非C肝硬変の肝発癌に関連する因子の検討
- Author(s)
  櫻井幸、他
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] C型慢性肝炎治療におけるIFN不応性に関わるIL28近傍遺伝子多型(SNP)と血球内IFNλ産生能の関連
- Author(s)
  村川美也子、朝比奈靖浩、中川美奈、後藤文男、大谷賢志、河合富貴子、谷口未樹、新田沙由梨、渡辺貴子、櫻井　幸、井津井康浩、東　正新、柿沼　晴、坂本直哉、渡辺　守
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京都・千代田区））
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-26460986
[Presentation] C型慢性肝炎患者におけるIFN治療応答性に関わる肝内ISG発現とIFNλ4の関連
- Author(s)
  村川美也子、朝比奈靖浩、北畑富貴子、中川美奈、永田紘子、金子　俊、後藤文男、谷口未樹、大谷賢志、新田沙由梨、渡辺貴子、櫻井　幸、井津井康浩、東　正新、柿沼　晴、飯島沙幸、田中靖人、坂本直哉、渡辺　守
- Organizer
  第51会日本肝臓学会総会
- Place of Presentation
  熊本ホテルキャッスル（熊本県・熊本市））
- Year and Date
  2015-05-21 – 2015-05-22
- Data Source
  KAKENHI-PROJECT-26460986
[Presentation] Antiviral effetcts and action mechanisms of novel N-(morpholine-4-carbonyloxy) amidine compounds against hepatitis C virus
- Author(s)
  Kusano-Kitazume A, Nishimura-Sakurai Y, et al.
- Organizer
  63rd Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-23790778
[Presentation] Impaired IL28B gene induction and poor IL28B promoter activity influenced by the IL28B minor allele are closely associated with a null response to interferon in chronic hepatitis C patients
- Author(s)
  Asahina Y, Nishimura-Sakurai Y, et al.
- Organizer
  63rd Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-23790778

1. 筬島裕子 (40451934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 坂本直哉 (10334418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. 朝比奈靖浩 (00422692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
4. 中川美奈 (30401342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. CHEN Cheng-hsin

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
6. 渡辺守

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 田中真二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 柿沼晴

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 米山光俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKURAI Yuki 櫻井 幸

Research Projects

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Co-Researchers

新規インターフェロンλ４遺伝子が関わるウイルス肝炎治療抵抗性機序の解明Principal Investigator

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Comprehensive analysis on genes and molecular pathways in host cells associated with Hepatitis C virus infection using next-generation sequencing technologyPrincipal Investigator

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細胞障害性HCV培養系を用いた重症C型肝炎発症機構の解析

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[Journal Article] Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features.2016

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[Journal Article] Efficacy of additional radiofrequency ablation after transcatheter arterial chemoembolization for intermediate hepatocellular carcinoma.2016

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[Journal Article] Evaluation of IFN resistance in newly established genotype 1b HCV cell culture system.2016

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[Journal Article] Impaired induction of IL28B and expression of IFNλ4 associated with non-response to interferon-based therapy in chronic hepatitis C.2015

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[Journal Article] 多血性肝細胞癌の検出能に関するGd-EOB-DTPA造影MRIとCTAP/CTHAとの比較検討2013

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[Journal Article] Association of ITPA gene variant and serum ribavirin concentration with blood cells decline in pegylated interferon-alfa plus ribavirin therapy for chronic hepatitis C.2013

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[Journal Article] 多血性肝細胞癌の検出能に関するGd-EOB-DTPA造影MRIとCTAP/CTHAとの比較検討2013

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[Journal Article] Association of ITPA gene variant and serum ribavirin concentration with blood cells decline in pegylated interferon-alfa plus ribavirin therapy for chronic hepatitis C2013

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[Journal Article] Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immunity2013

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[Journal Article] Identification of novel N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication2012

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[Journal Article] HCV-NS4B蛋白とIFN発現系シグナル分子との分子間相互作用の解析2012

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[Journal Article] The Japan Non-B, Non-C Liver Cirrhosis Study Group. Survey of non-B, non-C liver cirrhosis in Japan.2012

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[Journal Article] HCV-NS4B蛋白とIFN発現系シグナル分子との分子間相互作用の解析2012

Author(s)

SAKURAI Yuki 櫻井幸