Sanematsu Keisuke 實松敬介

… Alternative Names

SANEMATSU KEISUKE 實松敬介

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Researcher Number	70567502
Other IDs
Affiliation (Current)	2026: 九州大学, 歯学研究院, 講師
Affiliation (based on the past Project Information) *help	2019 – 2025: 九州大学, 歯学研究院, 講師 2016 – 2018: 九州大学, 歯学研究院, 助教 2017: 九州大学, 大学院歯学研究院, 助教 2011 – 2015: 九州大学, 歯学研究科(研究院), 助教 2013: 九州大学, 大学院・歯学研究院, 助教 2011 – 2012: 九州大学, 歯学研究院, 助教 2010: 九州大学, 大学院・歯学研究院, 助教
Review Section/Research Field	Principal Investigator Functional basic dentistry / Basic Section 57010:Oral biological science-related / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Functional basic dentistry / Basic Section 38050:Food sciences-related / Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 57010:Oral biological science-related / Medium-sized Section 57:Oral science and related fields / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator 味覚 / 甘味受容体 / 味覚受容体 / ミラクリン / 味覚修飾物質 / 受容体活性化機構 / 甘味 / ギムネマ酸 / グルマリン / 動的活性化機構 … More / 苦味受容体 / Gタンパク質共役型受容体 / TAS1R2/TAS1R3 / 甘味抑制物質 … More Except Principal Investigator 味覚 / 肥満 / 味覚障害 / エンドカンナビノイド / レプチン / 甘味 / 受容体 / 甘味阻害物質 / 甘味料 / 疎水性低分子化合物 / 味覚受容体 / 口腔免疫 / Big Data / ビックデータ / 味覚異常 / ビッグデータ / 味覚異常誘発薬剤 / 味覚障害誘発薬剤 / 味覚障害誘発性薬剤 / 味覚障害発症薬剤 / オルガノイド / カドヘリン / ラベルドライン / アクソンガイダンス / 味神経 / 味細胞 / バイオインスパイアードシステム / バイオマーカ / 簡易迅速・超高感度計測 / バイオマーカー / 匂い / 嗅覚 / 癌検知 / 神経科学 / 内分泌 / シグナル伝達 / 歯学 / コレシストキニン / 食欲調節ホルモン / 代謝センサー / 糖輸送体受容経路 / 口腔腸管味覚センサー / 味覚感受性 / 遺伝子多型性 / インクレチン / 食欲調節液性因子 / 口腔消化管味覚センサー / うま味受容体 / 人工味細胞 / 概日リズム / 甘味/うま味受容体 / 味覚修飾因子 / 人口味細胞 / 味覚健康科学 / ホルモン / 遺伝子多型 / 甘味受容体 Less

味覚障害と口腔内疾患とを結ぶ味覚-免疫連関機序の解明とその応用戦略
- Principal Investigator
  
  重村憲徳
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyushu University
Establishment of regulatory basis for nutrition and biological defense using taste receptorsPrincipal Investigator
- Principal Investigator
  
  實松敬介
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyushu University
The Nature of Sweetness Receptor Mechanisms in Humans
- Principal Investigator
  
  日下部裕子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  National Agriculture and Food Research Organization
Emergence of taste health medicine based on health checkup big data
- Principal Investigator
  
  Shigemura Noriatsu
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyushu University
Dynamic Interaction Mechanisms of Taste ReceptorsPrincipal Investigator
- Principal Investigator
  
  Sanematsu Keisuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
Elucidation of molecular basis of the onset of taste disorder based on pharmaco-genomics
- Principal Investigator
  
  Shigemura Noriatsu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
Elucidation of molecular, physiological, and pathological functions of taste receptors expressed throughout the bodyPrincipal Investigator
- Principal Investigator
  
  Sanematsu Keisuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
Elucidation of nutrient-specific taste cell-neuron matching mechanism
- Principal Investigator
  
  Shigemura Noriatsu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Kyushu University
Analysis of the sweet receptor as an energy sensorPrincipal Investigator
- Principal Investigator
  
  Sanematsu Keisuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Molecular basis of taste perception and humoral modulation of taste/hormone sensing cells in the oral-gut-brain circuit and its role in regulating food intake
- Principal Investigator
  
  NINOMIYA YUZO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Research and development of measuring systems of breast cancer by mimicking olfactory systems of nematode C. elegans
- Principal Investigator
  
  Toko Kiyoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Kyushu University
Analysis for the fuction of sweet receptorPrincipal Investigator
- Principal Investigator
  
  SANEMATSU Keisuke
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Molecular and Neural Mechanisms for Detection, Transmission and Modulation of taste signals derived from the oral cavity and gut
- Principal Investigator
  
  NINOMIYA Yuzo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Analysis for interaction between sweet receptor and taste modifiersPrincipal Investigator
- Principal Investigator
  
  SANEMATSU Keisuke
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Taste Signaling Mechanisms for the Regulation of Food Intake: Approaches to Establishment for Taste Health Science
- Principal Investigator
  
  NINOMIYA Yuzo
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University

[Book] 月刊化学Vol.78 No.8　甘味受容体の動的な活性化・不活性化メカニズムの解明ーー血糖値をコントロールできる甘味修飾物質の開発を目指して2023
- Author(s)
  實松敬介、重村憲徳
- Total Pages
  4
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-21K09818
[Book] 糖質・甘味のおいしさ評価と健康・調理・加工 (山野善正監修)　第4編3章ギムネマ酸の相互作用による甘味受容体抑制機構2022
- Author(s)
  實松　敬介
- Total Pages
  9
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437633
- Data Source
  KAKENHI-PROJECT-21K09818
[Book] Clinical Neuroscience vol.37 no.12 1444-14472019
- Author(s)
  實松敬介、重村憲徳、二ノ宮裕三
- Total Pages
  4
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-18K09523
[Book] 医学のあゆみ　各論：GPCR機能の新展開　【感覚】　味覚受容体2016
- Author(s)
  實松敬介、二ノ宮裕三
- Total Pages
  6
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-15K11045
[Book] 医学のあゆみ Vol 256, No.5（GPCR機能の新展開【感覚】）2016
- Author(s)
  實松敬介, 二ノ宮裕三
- Total Pages
  6
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-15H02571
[Book] 化学受容の科学：味覚受容体2012
- Author(s)
  實松　敬介、重村　憲徳、二ノ宮　裕三
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23792128
[Book] 化学受容の科学「味覚受容体」2012
- Author(s)
  實松敬介、重村憲徳、二ノ宮裕三
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23792128
[Book] 中山書店2011
- Author(s)
  實松　敬介、二ノ宮　裕三
- Publisher
  疾患モデルマウス表現型解析指南：味覚
- Data Source
  KAKENHI-PROJECT-23792128
[Book] 疾患モデルマウス表現型解析指南「味覚」2011
- Author(s)
  實松敬介、二ノ宮裕三
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23792128
[Journal Article] Receptor mechanism producing a sweet taste from plant aroma compounds2025
- Author(s)
  Horie Fuyumi、Sanematsu Keisuke、Yasumatsu Keiko、Hirokawa Takatsugu、Shigemura Noriatsu、Yamashita Atsuko、Kusakabe Yuko
- Journal Title
  
  Scientific Reports
  
  Volume: 15 Issue: 1 Pages: 6795-6795
- DOI
  10.1038/s41598-025-89711-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K02415, KAKENHI-PROJECT-23K27117, KAKENHI-PROJECT-24K02883, KAKENHI-PROJECT-24K08760
[Journal Article] Relationship between olfactory and gustatory functions: The Iwaki health promotion project 20192024
- Author(s)
  Yamauchi K、Matsushita D、Shimizume N、Kudo R、Kohama Y、Miyazaki A、Taguchi H、Hirao T、Kawabata F、Kawabata Y、Sanematsu K、Takai S、Yamazoe J、Anabuki K、Aoshima K、Takahashi Y、Goto S、Sasaki A、Shigemura N、Matsubara A
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 51 Issue: 3 Pages: 443-449
- DOI
  10.1016/j.anl.2023.12.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09818, KAKENHI-PROJECT-23K21565, KAKENHI-PROJECT-22K09915, KAKENHI-PROJECT-22K19672
[Journal Article] Activation Dynamics for the Taste Receptor as an Energy Sensor2024
- Author(s)
  Sanematsu Keisuke、Shigemura Noriatsu
- Journal Title
  
  Current Oral Health Reports
  
  Volume: 11 Issue: 4 Pages: 268-275
- DOI
  10.1007/s40496-024-00391-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H05006, KAKENHI-PROJECT-24K02883
[Journal Article] 甘味受容体の動的活性化機構およびpH 感受性機構2024
- Author(s)
  實松敬介、重村憲徳
- Journal Title
  
  味と匂学会誌
  
  Volume: 31 Pages: 150-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K02883
[Journal Article] The Antiarrhythmic Drug Flecainide Enhances Aversion to HCl in Mice.2023
- Author(s)
  Kawabata Y, Takai S, Sanematsu K, Yoshida R, Kawabata F, Shigemura N.
- Journal Title
  
  eNeuro.
  
  Volume: 10(9) Issue: 9 Pages: 0048-23
- DOI
  10.1523/eneuro.0048-23.2023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19672, KAKENHI-PROJECT-23K15979, KAKENHI-PROJECT-22K09915, KAKENHI-PROJECT-21K09818
[Journal Article] Cellular mechanisms of taste disturbance induced by the non-steroidal anti-inflammatory drug, diclofenac, in mice.2023
- Author(s)
  Hirayama A, Iwata S, Oike A, Kawabata Y, Nagasato Y, Takai S, Sanematsu K, Takahashi I, Shigemura N
- Journal Title
  
  Front Cell Neurosci.
  
  Volume: 17 Pages: 1279059-1279059
- DOI
  10.3389/fncel.2023.1279059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19672, KAKENHI-PROJECT-22K09905, KAKENHI-PROJECT-22K09915, KAKENHI-PROJECT-21H05006
[Journal Article] Adrenomedullin Enhances Mouse Gustatory Nerve Responses to Sugars via T1R-Independent Sweet Taste Pathway2023
- Author(s)
  Shusuke Iwata, Ryusuke Yoshida, Shingo Takai, Keisuke Sanematsu, Noriatsu Shigemura, Yuzo Ninomiya
- Journal Title
  
  Nutrients
  
  Volume: 15 Issue: 13 Pages: 2941-2941
- DOI
  10.3390/nu15132941
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09905, KAKENHI-PROJECT-21K09818, KAKENHI-PROJECT-21K19601
[Journal Article] The G protein‐coupled receptor <scp>GPRC5C</scp> is a saccharide sensor with a novel ‘off’ response2023
- Author(s)
  Kawabata Yuko、Takai Shingo、Sanematsu Keisuke、Iwata Shusuke、Kawabata Fuminori、Kanematsu Takashi、Jimi Eijiro、Shigemura Noriatsu
- Journal Title
  
  FEBS Letters
  
  Volume: 597 Issue: 15 Pages: 2006-2016
- DOI
  10.1002/1873-3468.14695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15979, KAKENHI-PROJECT-22K09905, KAKENHI-PROJECT-22K09915, KAKENHI-PROJECT-21K09817, KAKENHI-PROJECT-21K09818
[Journal Article] Prediction of dynamic allostery for the transmembrane domain of the sweet taste receptor subunit, TAS1R32023
- Author(s)
  Sanematsu Keisuke、Yamamoto Masato、Nagasato Yuki、Kawabata Yuko、Watanabe Yu、Iwata Shusuke、Takai Shingo、Toko Kiyoshi、Matsui Toshiro、Wada Naohisa、Shigemura Noriatsu
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 340-340
- DOI
  10.1038/s42003-023-04705-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15979, KAKENHI-PROJECT-22K09905, KAKENHI-PROJECT-22K09915, KAKENHI-PROJECT-21H05006, KAKENHI-PROJECT-19H03818
[Journal Article] Bisphosphonate affects the behavioral responses to HCl by disrupting farnesyl diphosphate synthase in mouse taste bud and tongue epithelial cells2022
- Author(s)
  Oike Asami、Iwata Shusuke、Hirayama Ayaka、Ono Yurika、Nagasato Yuki、Kawabata Yuko、Takai Shingo、Sanematsu Keisuke、Wada Naohisa、Shigemura Noriatsu
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 21246-21246
- DOI
  10.1038/s41598-022-25755-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09818, KAKENHI-PROJECT-22K09905, KAKENHI-PROJECT-22K09915, KAKENHI-PROJECT-19H03818
[Journal Article] In vitro and in silico characterization of adiponectin-receptor agonist dipeptides2021
- Author(s)
  Lee Yuna、Nakano Akihiro、Nakamura Saya、Sakai Kenta、Tanaka Mitsuru、Sanematsu Keisuke、Shigemura Noriatsu、Matsui Toshiro
- Journal Title
  
  npj Science of Food
  
  Volume: 5 Issue: 1 Pages: 29-29
- DOI
  10.1038/s41538-021-00114-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04863, KAKENHI-PROJECT-21K09818
[Journal Article] The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans2021
- Author(s)
  Serrano Joan、Seflova Jaroslava、Park Jihye、Pribadi Marsha、Sanematsu Keisuke、Shigemura Noriatsu、Serna Vanida、Yi Fanchao、Mari Andrea、Procko Erik、Pratley Richard E.、Robia Seth L.、Kyriazis George A.
- Journal Title
  
  Molecular Metabolism
  
  Volume: 54 Pages: 101339-101339
- DOI
  10.1016/j.molmet.2021.101339
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09818
[Journal Article] Gene expression profiling of α-gustducin-expressing taste cells in mouse fungiform and circumvallate papillae2021
- Author(s)
  YuYamada, ShingoTakai, Yu Watanabe, Ayana Osaki, Yuko Kawabata, Asami Oike, Ayaka Hirayama, Shusuke Iwata, Keisuke Sanematsu, ShojiTabata, Noriatsu Shigemura
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 557 Pages: 206-212
- DOI
  10.1016/j.bbrc.2021.04.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18457, KAKENHI-PROJECT-20K18458, KAKENHI-PROJECT-21K09818, KAKENHI-PROJECT-19H03818
[Journal Article] Drinking Ice-Cold Water Reduces the Severity of Anticancer Drug-Induced Taste Dysfunction in Mice2020
- Author(s)
  Osaki Ayana、Sanematsu Keisuke、Yamazoe Junichi、Hirose Fumie、Watanabe Yu、Kawabata Yuko、Oike Asami、Hirayama Ayaka、Yamada Yu、Iwata Shusuke、Takai Shingo、Wada Naohisa、Shigemura Noriatsu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 23 Pages: 8958-8958
- DOI
  10.3390/ijms21238958
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18457, KAKENHI-PROJECT-20K18458, KAKENHI-PROJECT-19H03818, KAKENHI-PROJECT-18K09523, KAKENHI-PROJECT-18K19652
[Journal Article] Expression of Renin-Angiotensin System Components in the Taste Organ of Mice2019
- Author(s)
  Shigemura Noriatsu、Takai Shingo、Hirose Fumie、Yoshida Ryusuke、Sanematsu Keisuke、Ninomiya Yuzo
- Journal Title
  
  Nutrients
  
  Volume: 11 Issue: 9 Pages: 2251-2251
- DOI
  10.3390/nu11092251
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09507, KAKENHI-PROJECT-18K09523, KAKENHI-PROJECT-18H02968, KAKENHI-PROJECT-18K19653, KAKENHI-PROJECT-17K17938, KAKENHI-PROJECT-18K19652, KAKENHI-PROJECT-19H03818
[Journal Article] Structural architecture of a dimeric class C GPCR based on co-trafficking of sweet taste receptor subunits2019
- Author(s)
  Park Jihye、Selvam Balaji、Sanematsu Keisuke、Shigemura Noriatsu、Shukla Diwakar、Procko Erik
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 13 Pages: 4759-4774
- DOI
  10.1074/jbc.ra118.006173
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09523, KAKENHI-PROJECT-18K19652, KAKENHI-PROJECT-19H03818
[Journal Article] Effects of insulin signaling on mouse taste cell proliferation2019
- Author(s)
  Takai Shingo、Watanabe Yu、Sanematsu Keisuke、Yoshida Ryusuke、Margolskee Robert F.、Jiang Peihua、Atsuta Ikiru、Koyano Kiyoshi、Ninomiya Yuzo、Shigemura Noriatsu
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 11 Pages: 1-16
- DOI
  10.1371/journal.pone.0225190
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09507, KAKENHI-PROJECT-18K09523, KAKENHI-PROJECT-18H02968, KAKENHI-PROJECT-18K19653, KAKENHI-PROJECT-17K17938, KAKENHI-PROJECT-18K19652, KAKENHI-PROJECT-19H03818
[Journal Article] 甘味受容体と甘味修飾物質との結合特性2018
- Author(s)
  實松敬介
- Journal Title
  
  日本味と匂学会誌
  
  Volume: 25 Pages: 7-12
- NAID
  130007395572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11045
[Journal Article] Bitter Taste Responses of Gustducin-positive Taste Cells in Mouse Fungiform and Circumvallate Papillae2018
- Author(s)
  Yoshida Ryusuke、Takai Shingo、Sanematsu Keisuke、Margolskee Robert F.、Shigemura Noriatsu、Ninomiya Yuzo
- Journal Title
  
  Neuroscience
  
  Volume: 369 Pages: 29-39
- DOI
  10.1016/j.neuroscience.2017.10.047
- NAID
  120006845804
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17938, KAKENHI-PROJECT-15H02571, KAKENHI-PROJECT-15K11044, KAKENHI-PROJECT-15K11045
[Journal Article] Diurnal Variation of Sweet Taste Recognition Thresholds Is Absent in Overweight and Obese Humans.2018
- Author(s)
  Sanematsu K, Nakamura Y, Nomura M, Shigemura N, Ninomiya Y.
- Journal Title
  
  Nutrients
  
  Volume: 10 Issue: 3 Pages: 297-297
- DOI
  10.3390/nu10030297
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09885, KAKENHI-PROJECT-15H02571, KAKENHI-PROJECT-15K11045
[Journal Article] Binding properties between human sweet receptor and sweet-inhibitor, gymnemic acids.2017
- Author(s)
  Sanematsu K, Shigemura N, Ninomiya Y.
- Journal Title
  
  Journal of Oral Biosciences.
  
  Volume: 59(3) Issue: 3 Pages: 127-130
- DOI
  10.1016/j.job.2017.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02571
[Journal Article] Leptin suppresses sweet taste responses of enteroendocrine STC-1 cells.2016
- Author(s)
  Jyotaki M, Sanematsu K, Shigemura N, Yoshida R, Ninomiya Y.
- Journal Title
  
  Neuroscience.
  
  Volume: 332 Pages: 76-87
- DOI
  10.1016/j.neuroscience.2016.06.036
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02571, KAKENHI-PROJECT-26462815, KAKENHI-PROJECT-15K11044, KAKENHI-PROJECT-15K11045
[Journal Article] Intracellular acidification is required for full activation of the sweet taste receptor by miraculin.2016
- Author(s)
  Sanematsu K, Kitagawa M, Yoshida R, Nirasawa S, Shigemura N, Ninomiya Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 22807-22807
- DOI
  10.1038/srep22807
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K11045, KAKENHI-PROJECT-26462815, KAKENHI-PROJECT-15H02571, KAKENHI-PROJECT-26670810
[Journal Article] Structure, function, and signaling of taste G-protein-coupled receptors2014
- Author(s)
  Sanematsu K, Yoshida R, Shigemura N, Ninomiya Y.
- Journal Title
  
  Curr Pharm Biotechnol
  
  Volume: 15 Pages: 951-61
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25861759
[Journal Article] Molecular mechanisms for sweet-suppressing effect of gymnemic acids2014
- Author(s)
  Sanematsu K, Kusakabe Y, Shigemura N, Hirokawa T, Nakamura S, Imoto T, Ninomiya Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Issue: 37 Pages: 25711-20
- DOI
  10.1074/jbc.m114.560409
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25861759
[Journal Article] Modulation of sweet responses of taste receptor cells2013
- Author(s)
  Yoshida R, Niki M, Jyotaki M, Sanematsu K, Shigemura N, Ninomiya Y
- Journal Title
  
  Semin Cell Dev Biol
  
  Volume: 24 Issue: 3 Pages: 226-31
- DOI
  10.1016/j.semcdb.2012.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249081, KAKENHI-PROJECT-23689076, KAKENHI-PROJECT-23792128
[Journal Article] Angiotensin II modulates salty and sweet taste sensitivities2013
- Author(s)
  N Shigemura, S Iwata, K Yasumatsu, T Ohkuri, N Horio, et al
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 33(15) Issue: 15 Pages: 6263-6277
- DOI
  10.1523/jneurosci.5599-12.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08216, KAKENHI-PROJECT-13J04608, KAKENHI-PROJECT-23249081, KAKENHI-PROJECT-23689076, KAKENHI-PROJECT-23792128, KAKENHI-PROJECT-24592803, KAKENHI-PROJECT-25861759
[Journal Article] Nordihydroguaiaretic acid inhibition of NFATc1 suppresses osteoclastogenesis and arthritis bone destruction in rats.2012
- Author(s)
  Li YJ, Kukita A, Watanabe T, Takano T, Qu P, Sanematsu K, Ninomiya Y, Kukita T.
- Journal Title
  
  Lab Invest.
  
  Volume: 92 Issue: 12 Pages: 1777-1787
- DOI
  10.1038/labinvest.2012.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249081, KAKENHI-PROJECT-23792128, KAKENHI-PROJECT-24592806
[Journal Article] Endocannabinoids selectively enhance sweet taste.2010
- Author(s)
  Yoshida R., Ohkuri T., Jyotaki M., Yasuo T., Horio N., Yasumatsu K., Sanematsu K., Shigemura N., Yamamoto T., Margolskee RF., Ninomiya Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 107:(2)
  
  Pages: 935-939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] New frontiers in gut nutrient sensor research : nutrient sensors in the gastrointestinal tract : modulation of sweet taste sensitivity by leptin.2010
- Author(s)
  Horio N., Jyotaki M., Yoshida R., Sanematsu K, Shigemura N., Ninomiya Y.
- Journal Title
  
  J Pharmacol Sci. 112(1)
  
  Pages: 8-12
- NAID
  10027908348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article]2010
- Author(s)
  實松敬介、二ノ宮裕三
- Journal Title
  
  肥満と糖尿病(丹水社)
  
  Pages: 211-212
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Endocannabinoids selectively enhance sweet taste.2010
- Author(s)
  Yoshida R., Ohkuri T., Jyotaki M., Yasuo T., Horio N., Yasumatsu K., Sanematsu K., Shigemura N., Yamamoto T., Margolskee RE, Ninomiya Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 107(2)
  
  Pages: 935-939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] ヒトTIR2/T1R3に対するギムネマ酸の相互作用の部位の同定2009
- Author(s)
  實松敬介、重村憲徳、上瀧将史、中村誠司、井元敏明、二ノ宮裕三
- Journal Title
  
  日本味と匂学会誌 16(3)
  
  Pages: 287-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Genetic and Molecular Basis of Individual Differences in Human Umami Taste Perception2009
- Author(s)
  Shigemura N., Shirosaki S., Sanematsu K., Yoshida R., Ninomiya Y
- Journal Title
  
  PLoS ONE 4(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Genetically-increased taste cell population with Galpha-gustducin-coupled sweet receptors is associated with increase of gurmarin-sensitive taste nerve fibers in mice.2009
- Author(s)
  Yasumatsu K., Ohkuri T, Sanematsu K., Shigemura N., Katsukawa H., Sako N., Ninomiya Y.
- Journal Title
  
  BMC Neurosci. 10(1)
  
  Pages: 152-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Variation in umami perception and its receptor candidate genes in rodents and humans.2009
- Author(s)
  Shigemura N., Shirosaki S., Ohkuri T., Sanematsu K., Islam AA., Ogiwara Y., Kawai M., Yoshida R., Ninomiya Y.
- Journal Title
  
  Am. J. Clin. Nutr 90(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Modulation and transmission of sweet taste information for energy homeostasis.2009
- Author(s)
  Sanematsu K., Horio N., Murata Y., Yoshida R., Ohkuri T., Shigemura N., Ninomiya Y.
- Journal Title
  
  Ann NY Acad Sci. 1170
  
  Pages: 102-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Variation in umami perception and in candidate genes for the umami receptor in mice and humans.2009
- Author(s)
  Shigemura N., Shirosaki S., Ohkuri T., Sanematsu K., Islam AA., Ogiwara Y., Kawai M., Yoshida R., Ninomiya Y.
- Journal Title
  
  Am.J.Clin. Nutr 90:(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Genetic and molecular basis of individual differences in human umami taste perception.2009
- Author(s)
  Shigemura N., Shirosaki S., Sanematsu K., Yoshida R., Ninomiya Y.
- Journal Title
  
  PLoS ONE 4:(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Genetically-increased taste cell population with G(alpha)-gustducin-coupled sweet receptors is associated with increase of gurmarin-sensitive taste nerve fibers in mice.2009
- Author(s)
  Yasumatsu K., Ohkuri T., Sanematsu K., Shigemura N., Katsukawa H., Sako N., Ninomiya Y.
- Journal Title
  
  BMC Neurosci. 10(1)
  
  Pages: 152-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Variation in umami perception and its receptor candidate genes in rodents and humans.2009
- Author(s)
  Shigemura N, Shirosaki S, Ohkuri T, Sanematsu K, Islam AA, Ogiwara Y, Kawai M, Yoshida R, Ninomiya Y
- Journal Title
  
  Am. J. Clin. Nutr (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Modulation and transmission of sweet taste information for energy homeostasis.2009
- Author(s)
  Sanematsu K, Horio N, Murata Y, Yoshida R, Ohkuri T, Shigemura N, Ninomiya Y
- Journal Title
  
  Ann NY Acad Sci. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Diurnal variation of human sweet taste recognition thresholds is correlated with plasma leptin levels.2008
- Author(s)
  Nakamura Y., Sanematsu K., Ohta R., Shirosaki S., Koyano K., Nonaka K., Shigemura N., Ninomiya Y.
- Journal Title
  
  Diabetes 57:(10)
  
  Pages: 2661-2665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Diurnal variation of human sweet taste recpgnition thresholds is correlated with plasma leptin levels2008
- Author(s)
  Nakamura Y, Sanematsu K, Ohta R, Shirosaki S, Koyano K, Nonaka K, Shigemura N, Ninomiya Y.
- Journal Title
  
  Diabetes 57
  
  Pages: 2661-2665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Diurnal Variation of Human Sweet Taste Recognition Threholds Is Correlated With Plasma Leptin Levels2008
- Author(s)
  Nakamura Y, Sanematsu K, Ohta R, Shirosaki S, Koyano K, Nonaka K, Shigemura N, Ninomiya Y.
- Journal Title
  
  DIABETES 57
  
  Pages: 2661-2665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Taste responsiveness of fungiform taste cells with action potentials.2006
- Author(s)
  Yoshida R, Shigemura N, Sanematsu K, Yasumatsu K, Ishizuka S, Ninomiya Y
- Journal Title
  
  J. Neurophysiol. 96
  
  Pages: 3088-3095
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Taste responsiveness of fungiform taste cells with action potentials2006
- Author(s)
  Yoshida R, Shigemura N, Sanematsu K, Yasumatsu K, Ishizuka S, Ninomiya Y.
- Journal Title
  
  J Neurophysiol 96
  
  Pages: 3088-3095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Journal Article] Taste responsiveness of fungiform taste cells with action potentials.2006
- Author(s)
  Yoshida R., Shigemura N., Sanematsu K., Yasumatsu K., Ishizuka S., Ninomiya Y.
- Journal Title
  
  J Neurophysiol 96:(6)
  
  Pages: 3088-3095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] 味覚受容体の種特異的感受性のメカニズム2024
- Author(s)
  實松敬介、永里侑貴、川端由子, 髙井信吾, 重村憲徳
- Organizer
  第66回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-24K02883
[Presentation] Molecular mechanisms of sweet taste receptor activation/inactivation and species-specific sensitivity2024
- Author(s)
  Keisuke Sanematsu,Masato Yamamoto, Yuki Nagasato, Yuko Kawabata, Shingo Takai, Noriatsu Shigemura
- Organizer
  日本生理学会第101回大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09818
[Presentation] 味覚受容機構のデジタル化における現状2024
- Author(s)
  實松　敬介
- Organizer
  第19回日本感性工学会春季大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09818
[Presentation] 甘味受容体の動的活性化の分子機構2024
- Author(s)
  實松敬介
- Organizer
  日本味と匂学会第58回大会
- Invited
- Data Source
  KAKENHI-PROJECT-24K02883
[Presentation] The sweet taste mechanism of the plant aroma compound2024
- Author(s)
  Horie Fuyumi、Sanematsu Keisuke、Yasumatsu Keiko、Hirokawa Takatsugu、Shigemura Noriatsu、Yamashita Atsuko、Kusakabe Yuko
- Organizer
  The 19th International Symposium on Olfaction and Taste
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K08760
[Presentation] 甘味受容体サブユニットTAS1R3 の膜貫通ドメインにおける動的機能の解明2023
- Author(s)
  實松敬介、山本真隆人、川端由子、渡邉雄、岩田周介、髙井信吾、重村憲徳
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21K09818
[Presentation] Elucidation for the activation/inactivation dynamics of the sweet taste receptor2023
- Author(s)
  Keisuke Sanematsu, Masato Yamamoto, Yuki Nagasato, Yuko Kawabata, Shingo Takai, Noriatsu Shigemura
- Organizer
  ISMNTOP2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09818
[Presentation] 甘味受容体サブユニットTAS1R3の活性化・不活性化メカニズムの解明2023
- Author(s)
  實松　敬介，川端　由子, 渡邉　雄, 岩田　周介, 髙井　信吾, 重村　憲徳
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09818
[Presentation] サッカリンの種特異的感受性の分子メカニズム2023
- Author(s)
  實松　敬介、永里　侑貴、山本　真隆人、平山彩夏、今村　恵美子、川端　由子、髙井　信吾、重村　憲徳
- Organizer
  日本味と匂学会第57回大会
- Data Source
  KAKENHI-PROJECT-21K09818
[Presentation] カプサイシンのマウス味覚神経応答に対する影響2022
- Author(s)
  岩田周介，吉田竜介，高井信吾，實松敬介，重村憲徳，二ノ宮裕三
- Organizer
  第64回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] mTORシグナリングを介した味蕾の体内栄養感知機構2022
- Author(s)
  高井信吾，岩田周介，實松敬介，大野友理花，平山彩夏，尾池麻未，重村憲徳
- Organizer
  日本味と匂学会第56会大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] カプサイシンがマウス鼓索神経応答に及ぼす影響2022
- Author(s)
  岩田周介，吉田竜介，高井信吾，實松敬介，重村憲徳，二ノ宮裕三
- Organizer
  日本味と匂学会第56会大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] Visualization of taste2022
- Author(s)
  Sanematsu Keisuke
- Organizer
  22nd IUNS-ICN International Congress of Nutrition
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09818
[Presentation] ビスホスホネート長期投与による酸味溶液に対する忌避性行動の増強2022
- Author(s)
  尾池麻未，岩田周介，平山彩夏，菅原友佳，大野友里花，川端由子，高井信吾，實松敬介，和田尚久，重村憲徳
- Organizer
  五感応用デバイス研究開発センター・合同セミナー
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 味蕾の基底細胞は mTOR シグナリングを介して体内栄養状態をモニターする2022
- Author(s)
  高井信吾，岩田周介，實松敬介，川端由子，平山彩夏，渡邉雄，重村憲徳
- Organizer
  第64回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] ビスホスホネート長期投与による酸味溶液に対する忌避性行動の増強2022
- Author(s)
  尾池麻未，岩田周介，平山彩夏，大野友里花，永里侑貴, 川端由子，高井信吾，實松敬介，和田尚久，重村憲徳
- Organizer
  日本味と匂学会第56会大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 不整脈薬フレカイニドはマウスの酸味応答性を増強する2021
- Author(s)
  川端由子，高井信吾，吉田竜介，實松敬介，川端二功，重村憲徳
- Organizer
  日本味と匂学会第55回大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 抗不整脈薬フレカイニドの酸味増強作用とその分子機構の解析2021
- Author(s)
  川端由子，高井信吾，吉田竜介，實松敬介，重村憲徳
- Organizer
  第63回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] ビスホスホネート製剤由来味覚障害の分子機構の解明2021
- Author(s)
  尾池麻未，岩田周介，平山彩夏，菅原友佳，大野友里花，川端由子，高井信吾，實松敬介，和田尚久，重村憲徳
- Organizer
  日本味と匂学会第55回大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 味覚受容体の動的活性化・不活性化メカニズムの理解2021
- Author(s)
  實松　敬介
- Organizer
  感覚研究コンソーシアム：第一回味覚ワーキンググループ
- Invited
- Data Source
  KAKENHI-PROJECT-21K09818
[Presentation] 非ステロイド性抗炎症薬長期投与によるマウス甘味・うま味感受性の抑制2021
- Author(s)
  平山彩夏，岩田周介，尾池麻未，渡邊雄，川端由子，實松敬介，高井信吾，高橋一郎，重村憲徳
- Organizer
  第63回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 体内の栄養状態を反映したマウス味細胞におけるmechanistic target of rapamycin（mTOR）活性化2021
- Author(s)
  高井信吾，岩田周介，實松敬介，重村憲徳
- Organizer
  第63回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] ナトリウム利尿ペプチドによる塩味感受性調節機構2021
- Author(s)
  菅原友佳，高井信吾，川端由子，岩田周介，渡邊雄，尾池麻未，平山彩夏，實松敬介，田畑正志，重村憲徳
- Organizer
  日本味と匂学会第55回大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] アドレノメデュリンによるマウス鼓索神経甘味応答増強機構の解明2021
- Author(s)
  岩田周介，吉田竜介，高井信吾，實松敬介，重村憲徳，二ノ宮裕三
- Organizer
  第63回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] アドレノメデュリンによるマウス鼓索神経甘味応答増強機構の解明2021
- Author(s)
  岩田周介，吉田竜介，高井信吾，實松敬介，重村憲徳，二ノ宮裕三
- Organizer
  日本味と匂学会第55回大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 甘味受容体の動的活性化・不活性化メカニズム2021
- Author(s)
  實松　敬介、山本　真隆人、川端　由子、岩田　周介、髙井　信吾、重村　憲徳
- Organizer
  日本味と匂学会第55回大会
- Data Source
  KAKENHI-PROJECT-21K09818
[Presentation] マウス味蕾における mechanistic target of rapamycin(mTOR)の機能探索2021
- Author(s)
  高井信吾，岩田周介，實松敬介，重村憲徳
- Organizer
  日本味と匂学会第55回大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] ナトリウム利尿ペプチドが塩味の行動応答に及ぼす影響2021
- Author(s)
  菅原友佳, 高井信吾, 川端由子, 岩田周介, 渡邊雄, 尾池麻未,平山彩夏, 實松敬介, 田畑正志, 重村憲徳
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 甘味受容体の動的活性化・不活性化メカニズム2021
- Author(s)
  實松敬介，山本真隆人，川端由子，岩田周介，高井信吾，重村憲徳
- Organizer
  日本味と匂学会第55回大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 抗不整脈薬フレカイニドによる酸味感受性の増強2020
- Author(s)
  川端由子、髙井信吾、吉田竜介、實松敬介、重村憲徳
- Organizer
  第62回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 食事への興味・食習慣が味覚閾値に及ぼす影響について2020
- Author(s)
  小濱佑介、川端由子、宮崎明子、田口大夢、川端二功、松原篤、工藤玲子、清水目奈美、重村憲徳、實松敬介、高井信吾、山添淳一、平尾宜司、上野正一、村下公一、安藤雅峻、沢田かほり、井原一成、山本佳弘、中路重之
- Organizer
  日本味と匂学会第54回大会
- Data Source
  KAKENHI-PROJECT-18K19652
[Presentation] 状乳頭および有郭乳頭におけるGustducin発現細胞のSingle cell RNA-Seq解析2020
- Author(s)
  山田優、高井信吾、渡邉雄、尾崎礼奈、川端由子、尾池麻未、平山彩夏、岩田周介、實松敬介、西村正太郎、田畑正志、重村憲徳
- Organizer
  日本味と匂学会第54回大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 味覚受容体再構築系におけるCa2+イメージングを用いた受容体機能解析2020
- Author(s)
  實松敬介，重村憲徳
- Organizer
  第62回歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 抗不整脈薬フレカイニドによる酸味感受性の増強2020
- Author(s)
  川端由子、髙井信吾、吉田竜介、實松敬介、重村憲徳
- Organizer
  第62回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-18K19652
[Presentation] The effects of flecainide on taste bud organoid growth and behavioral sour taste response in mice.2020
- Author(s)
  Kawabata Y, Takai S, Yoshida R, Sanematsu K, Kawabata F, Shigemura N.
- Organizer
  ISOT2020
- Data Source
  KAKENHI-PROJECT-18K09523
[Presentation] 味覚受容体再構築系におけるCa2+イメージングを用いた受容体機能解析2020
- Author(s)
  實松　敬介，重村　憲徳
- Organizer
  第62回　歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09523
[Presentation] 甘味受容体感受性における低pHによる抑制効果の分子メカニズム2020
- Author(s)
  實松敬介、二ノ宮裕三、重村憲徳
- Organizer
  第97回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09523
[Presentation] The effects of flecainide on taste bud organoid growth and behavioral taste responses in mice2020
- Author(s)
  Kawabata Y, Takai S, Yoshida R, Sanematsu K, Kawabata F, Shigemura N
- Organizer
  ISOT2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] The effects of flecainide on taste bud organoid growth and behavioral taste responses in mice2020
- Author(s)
  Kawabata Y, Takai S, Yoshida R, Sanematsu K, Kawabata F, Shigemura N
- Organizer
  ISOT2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19652
[Presentation] 茸状乳頭および有郭乳頭におけるGustducin発現細胞のSingle cell RNA-Seq解析2020
- Author(s)
  山田優、高井信吾、渡邉雄、尾崎礼奈、川端由子、尾池麻未、平山彩夏、岩田周介、實松敬介、西村正太郎、田畑正志、重村憲徳
- Organizer
  日本味と匂学会第54回大会
- Data Source
  KAKENHI-PROJECT-18K19652
[Presentation] 事への興味・食習慣が味覚閾値に及ぼす影響について2020
- Author(s)
  小濱佑介、川端由子、宮崎明子、田口大夢、川端二功、松原篤、工藤玲子、清水目奈美、重村憲徳、實松敬介、高井信吾、山添淳一、平尾宜司、上野正一、村下公一、安藤雅峻、沢田かほり、井原一成、山本佳弘、中路重之
- Organizer
  日本味と匂学会第54回大会
- Data Source
  KAKENHI-PROJECT-19H03818
[Presentation] 味覚受容体再構築系におけるCa2+イメージングを用いた受容体機能解析2020
- Author(s)
  實松敬介，重村憲徳
- Organizer
  第62回歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19652
[Presentation] 低pH条件はサッカリンの甘味感受性を低下させる2019
- Author(s)
  實松敬介、尾崎礼奈、中林開人、重村憲徳
- Organizer
  日本味と匂学会第53回大会
- Data Source
  KAKENHI-PROJECT-18K09523
[Presentation] Molecular mechanisms of suppressing and modifying effects on sweet taste receptor sensitivity2019
- Author(s)
  Keisuke Sanematsu, Yuzo Ninomiya, Noriatsu Shigemura
- Organizer
  ECRO 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09523
[Presentation] 低pH条件下における甘味受容体感受性の解析2018
- Author(s)
  實松敬介，尾崎礼奈，中林開人，二ノ宮裕三，重村憲徳
- Organizer
  日本味と匂学会第52回大会
- Data Source
  KAKENHI-PROJECT-18K19652
[Presentation] Agonistic/antagonistic properties of sweet taste receptor2018
- Author(s)
  Sanematsu K, Shigemura N, Ninomiya Y
- Organizer
  第56回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09523
[Presentation] グルカゴン様ペプチド-１受容体遺伝子多型と甘味認知閾値との関連について2018
- Author(s)
  實松敬介, 井上真由子, 髙井信吾, 重村憲徳, 二ノ宮裕三
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09523
[Presentation] 味覚障害誘発薬剤がマウス味蕾オルガノイドへ与える影響2018
- Author(s)
  川端由子，高井信吾，吉田竜介，實松敬介，重村憲徳
- Organizer
  第60回　歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K19652
[Presentation] Intracellular acidification participates in full activation of the sweet taste receptor in taste-modifying effect of miraculin.2017
- Author(s)
  Sanematsu K, Kitagawa M, Yoshida R, Nirasawa S, Shigemura N, Ninomiya Y.
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松、アクトシティ浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] 塩味感受性とその可変性2017
- Author(s)
  重村憲徳，吉田竜介，實松敬介，高井信吾，岩田周介，安松啓子，二ノ宮裕三
- Organizer
  第59回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] 甘味受容体と甘味修飾物質との結合特性2017
- Author(s)
  實松敬介
- Organizer
  日本味と匂学会第51回大会
- Invited
- Data Source
  KAKENHI-PROJECT-15K11045
[Presentation] ミラクリンの味覚修飾効果における甘味受容体の完全活性化には細胞内酸性化が関与する2017
- Author(s)
  實松敬介，北川昌幸，吉田竜介，韮澤悟，重村憲徳，二ノ宮裕三
- Organizer
  第94回日本生理学会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K11045
[Presentation] Multiple sweet taste signaling pathways in the mouse periphery.2017
- Author(s)
  Ninomiya Y, Yasumatsu K, Yoshida R, Takai S, Iwata S, Sanematsu K, Shigemura N, Margolskee RF.
- Organizer
  AChemS2017.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] 甘味受容体と甘味修飾物質との結合特性2017
- Author(s)
  實松敬介
- Organizer
  日本味と匂学会第51回大会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] Responsiveness of gustducin-expressing taste cells to multiple bitter compounds.2016
- Author(s)
  Yoshida R, Takai S, Sanematsu K, Margolskee RF, Shigemura N, Ninomiya Y.
- Organizer
  The 15th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception.
- Place of Presentation
  福岡、九州大学
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] Responsiveness of gustducin-expressing taste cells to multiple bitter compounds2016
- Author(s)
  Yoshida R, Takai S, Sanematsu K, Margolskee RF, Shigemura N, Ninomiya Y
- Organizer
  ISMNTOP2016
- Place of Presentation
  福岡
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11045
[Presentation] 甘味受容体TAS1R2/TAS1R3 におけるギムネマ酸の甘味抑制効果の分子メカニズム2016
- Author(s)
  實松敬介
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K11045
[Presentation] Intracellular acidification is involved in full activation of the sweet taste receptor by miraculin2016
- Author(s)
  Sanematsu K, Kitagawa M, Yoshida R, Nirasawa S, Shigemura N, Ninomiya Y.
- Organizer
  17th International Symposium on Olfaction and Taste JASTS 50 th Annual Meeting
- Place of Presentation
  横浜
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11045
[Presentation] Gustatory responses of taste receptor cells expressing fluorescent proteins in transgenic mice.2016
- Author(s)
  Yoshida R, Yasumatsu-Nakano K, Sanematsu K, Shigemura N, Ninomiya Y.
- Organizer
  17th International Symposium on Olfaction and Taste (ISOT2016)
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2016-06-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] ミラクリンによる甘味誘導効果の分子メカニズム2016
- Author(s)
  實松敬介，吉田竜介，重村憲徳，二ノ宮裕三
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌、札幌コンベンションセンター
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] 甘味受容体TAS1R2/TAS1R3におけるギムネマ酸の甘味抑制効果の分子メカニズム2016
- Author(s)
  實松敬介，重村憲徳，二ノ宮裕三
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌、札幌コンベンションセンター
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] Intracellular acidification is involved in full activation of the sweet taste receptor by miraculin.2016
- Author(s)
  Sanematsu K, Kitagawa M, Yoshida R, Nirasawa S, Shigemura N, Ninomiya Y.
- Organizer
  17th International Symposium on Olfaction and Taste (ISOT2016)
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] ホルモンによる味覚（塩味・甘味）感受性調節2016
- Author(s)
  重村憲徳, 吉田竜介, 安松啓子, 大栗弾宏, 岩田周介, 高井信吾, 上瀧将史, 仁木麻由, 實松敬介, 二ノ宮裕三
- Organizer
  第67回日本生物工学会
- Place of Presentation
  鹿児島、城山観光ホテル
- Year and Date
  2016-10-26
- Invited
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] Intracellular acidification is implicated in full activation of the sweet taste receptor in taste-modifying effect of miraculin2016
- Author(s)
  Sanematsu K, Kitagawa M, Yoshida R, Nirasawa S, Shigemura N, Ninomiya Y.
- Organizer
  ISMNTOP2016
- Place of Presentation
  福岡
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11045
[Presentation] ミラクリンによる甘味誘導効果の分子メカニズム2016
- Author(s)
  實松敬介，吉田竜介，重村憲徳，二ノ宮裕三
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-15K11045
[Presentation] Gustatory responses of taste receptor cells expressing fluorescent proteins in transgenic mice2016
- Author(s)
  Yoshida R, Yasumatsu-Nakano K, Sanematsu K, Shigemura N, Ninomiya Y.
- Organizer
  17th International Symposium on Olfaction and Taste JASTS 50 th Annual Meeting
- Place of Presentation
  横浜
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11045
[Presentation] Intracellular acidification is implicated in full activation of the sweet taste receptor in taste-modifying effect of miraculin.2016
- Author(s)
  Sanematsu K, Kitagawa M, Yoshida R, Nirasawa S, Shigemura N, Ninomiya Y.
- Organizer
  The 15th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception.
- Place of Presentation
  福岡、九州大学
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] 味覚受容体の機能（塩味と甘味）2016
- Author(s)
  重村憲徳, 吉田竜介, 安松啓子, 大栗弾宏, 岩田周介, 高井信吾, 上瀧将史, 仁木麻由, 實松敬介, 二ノ宮裕三
- Organizer
  日本薬学会第136回年会
- Place of Presentation
  神奈川、パシフィコ横浜
- Year and Date
  2016-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] 甘味受容体T1R2/T1R3に対する味覚修飾作用の解析2015
- Author(s)
  實松敬介, 重村憲徳, 二ノ宮裕三
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  新潟、朱鷺メッセ
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] マウス鼓索神経における脂肪酸応答単一神経の記録2015
- Author(s)
  安松啓子, 吉田竜介, 實松敬介, 重村憲徳, 二ノ宮裕三
- Organizer
  日本味と匂学会第49回大会
- Place of Presentation
  岐阜、じゅうろくプラザ
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-15H02571
[Presentation] 甘味受容体T1R2/T1R3に対する味覚修飾作用の解析2015
- Author(s)
  實松敬介、重村憲徳、二ノ宮裕三
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K11045
[Presentation] ホルモンによる塩味および甘味感受性調節2014
- Author(s)
  重村憲徳、吉田竜介、安松啓子、大栗弾宏、岩田周介、高井信吾、上瀧将史、仁木真由、實松敬介、二ノ宮裕三
- Organizer
  第９１回日本生理学会大会
- Place of Presentation
  鹿児島大学、鹿児島
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] 腸管内分泌細胞の味覚感受性に対するレプチンの効果2013
- Author(s)
  上瀧将史、實松敬介、重村憲徳、二ノ宮裕三
- Organizer
  第６４回西日本生理学会
- Place of Presentation
  産業医科大学、北九州
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] ホルモンによる味覚修飾と摂食調節2013
- Author(s)
  重村憲徳、吉田竜介、安松啓子、大栗弾宏、岩田周介、高井信吾、上瀧将史、仁木真由、實松敬介、二ノ宮裕三
- Organizer
  日本味と匂学会大会第４７回大会
- Place of Presentation
  仙台市民会館、仙台
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] 甘味受容体機能の解析2013
- Author(s)
  實松敬介、日下部裕子、重村憲徳、広川貴次、井元敏明、二ノ宮裕三
- Organizer
  日本味と匂学会第47回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25861759
[Presentation] ギムネマ酸の甘味抑制メカニズム2013
- Author(s)
  實松敬介、日下部裕子、重村憲徳、広川貴次、井本敏明、二ノ宮裕三
- Organizer
  日本味と匂学会大会第４７回大会
- Place of Presentation
  仙台市民会館、仙台
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] 肥満者におけるレプチンおよび味覚日内変動の検索2012
- Author(s)
  實松敬介、北川昌幸、中村由紀、野村政壽、重村憲徳、二ノ宮裕三
- Organizer
  味と匂学会第46回大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] Diurnal variation of plasma leptin levels and taste recognition thresholds in over-weight and obese subjects2012
- Author(s)
  Sanematsu K, Kitagawa M, Nakamura Y, Nomura Y, Shigemura N, Ninomiya Y
- Organizer
  AChemS
- Place of Presentation
  Hyatt Huntington beach, CA, USA
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] 腸管内分泌細胞の味覚感受性に対するカンナビノイドの効果2012
- Author(s)
  上瀧将史、實松敬介、重村憲徳、二ノ宮裕三
- Organizer
  味と匂学会第46回大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] 甘味受容細胞の感受性抑制機構2012
- Author(s)
  實松敬介、二ノ宮裕三
- Organizer
  病態生理学会
- Place of Presentation
  大分(招待講演)
- Year and Date
  2012-08-03
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] 肥満者におけるレプチンおよび味覚日内変動の検索2012
- Author(s)
  實松敬介、北川昌幸、中村由紀、野村政壽、重村憲徳、二ノ宮裕三
- Organizer
  日本味と匂学会
- Place of Presentation
  大阪大学（大阪）
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] Lack of diurnal variation of sweet recognition thresholds in over-weight and obese humans2012
- Author(s)
  Sanematsu K, Kitagawa M, Nakamura Y, Nomura M, Shigemura N, Ninomiya Y
- Organizer
  ISOT XVI
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] Diurnal variation of plasma leptin levels and taste recognition thresholds in over-weight and obese subjects2012
- Author(s)
  Sanematsu K, Kitagawa M, Nakamura Y, Nomura M, Shigemura N, Ninomiya Y
- Organizer
  AChemS 2012
- Place of Presentation
  Huntington Beach, USA
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] Lack of diurnal variation of sweet recognition thresholds in over-weight and obese subjects.2012
- Author(s)
  Sanematsu K, Kitagawa M, Nakamura Y, Nomura Y, Shigemura N, Ninomiya Y
- Organizer
  ISOT
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] Diurnal variation of plasma leptin levels and taste recognition thresholds in over-weight and obese subjects.2012
- Author(s)
  Sanematsu K, Kitagawa M, Nakamura Y, Nomura M, Shigemura N, Ninomiya Y .
- Organizer
  AChemS 2012
- Place of Presentation
  Huntington Beach, USA
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] 腸管内分泌細胞の味覚感受性に対するカンナビノイドの効果2012
- Author(s)
  上瀧将史、實松敬介、重村憲徳、二ノ宮裕三
- Organizer
  日本味と匂学会
- Place of Presentation
  大阪大学（大阪）
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] 甘味抑制物質グルマリンの分子メカニズム2011
- Author(s)
  實松敬介、二ノ宮裕三
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] Leptin modulates sweet sensitivities in enteroendocrine STC-1 cells2011
- Author(s)
  Jyotaki M, Niki M, Sanematsu K, Shigemura N, Ninomiya Y
- Organizer
  Annual Meeting of the Society for the Study of Ingestive Behavior
- Place of Presentation
  Clearwater, Florida, USA
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] Molecular mechanisms for sweet-suppressing effects of gymnemic acid and gurmarin2011
- Author(s)
  Sanematsu K, Ninomiya Y
- Organizer
  第45回日本味と匂学会
- Place of Presentation
  石川、石川県立音楽堂(招待講演)
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] 甘味受容体T1R2/T1R3に対する味覚修飾物質の相互作用部位の解析2011
- Author(s)
  實松敬介、二ノ宮裕三
- Organizer
  第53回歯科基礎医学会
- Place of Presentation
  岐阜、長良川国際会議場(招待講演)
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] 甘味抑制物質グルマリンの分子メカニズム(Molecular mechanism of the sweet taste inhibitor : gurmarin)2011
- Author(s)
  實松敬介、二ノ宮裕三
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  神奈川、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] 甘味抑制物質グルマリンの分子メカニズム2011
- Author(s)
  實松　敬介、二ノ宮　裕三
- Organizer
  第34回日本神経科学大会(招待講演)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] 腸管内分泌細胞の味覚感受性に対するレプチンの効果2011
- Author(s)
  上瀧将史、實松敬介、重村憲徳、二ノ宮裕三
- Organizer
  第45回日本味と匂学会
- Place of Presentation
  石川、石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-23249081
[Presentation] Molecular mechanisms for sweet-suppressing effects of gymnemic acid and gurmarin2011
- Author(s)
  實松　敬介、二ノ宮　裕三
- Organizer
  日本味と匂学会第45回大会(招待講演)
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] Molecular mechanisms for sweet-suppressing effects of gymnemic acid and gurmarin2011
- Author(s)
  實松敬介、二ノ宮裕三
- Organizer
  日本味と匂学会第45回大会
- Place of Presentation
  金沢
- Year and Date
  2011-10-01
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] 甘味受容体 T1r2/T1r3 に対する味覚修飾物質の相互作用部位の解析2011
- Author(s)
  實松敬介、二ノ宮裕三
- Organizer
  第53回歯科基礎医学会学術大会・総会
- Place of Presentation
  岐阜
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] 甘味受容体T1R2/T1R3に対する味覚修飾物質の相互作用部位の解析2011
- Author(s)
  實松　敬介、二ノ宮　裕三
- Organizer
  第53回歯科基礎医学会学術大会・総会(招待講演)
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] Molecular mechanisms between sweet receptors and taste modifiers2010
- Author(s)
  Sanematsu K, Ninomiya Y
- Organizer
  PACIFICHEM2010
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] Identification of the gurmarin interaction site within the mouse sweet receptor2010
- Author(s)
  Sanematsu K, Ninomiya Y
- Organizer
  第8回味覚嗅覚の分子神経機構
- Place of Presentation
  福岡市、九州大学病院地区コラボステーション
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] ギムネマ酸による甘味抑制効果の分子メカニズム2010
- Author(s)
  實松敬介、重村憲徳、上瀧将史、中村誠司、井元敏明、二ノ宮裕三
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市、盛岡市民文化ホール他
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] 甘味受容体T1R2/T1R3に対するグルマリン相互作用部位の同定2010
- Author(s)
  實松敬介、二ノ宮裕三
- Organizer
  第52回歯科基礎医学会総会
- Place of Presentation
  東京都、タワーホール船堀
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] 遺伝子変異(SNP)と味覚センサー機能の変化2010
- Author(s)
  重村憲徳、荻原葉子、實松敬介、河合美佐子、吉田竜介、二ノ宮裕三
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市、盛岡市民文化ホール他
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] グルマリンによる甘味抑制効果の分子メカニズム2010
- Author(s)
  實松敬介、二ノ宮裕三
- Organizer
  第44回日本味と匂学会
- Place of Presentation
  北九州市、北九州国際会議場
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] Molecular mechanisms between sweet receptors and taste modifiers.2010
- Author(s)
  Sanematsu K, Ninomiya Y
- Organizer
  PACIFICHEM2010,(招待講演)
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] 内因性カンナビノイドはマウスの甘味応答を増大させる(Endocannabinoids enhance sweet taste sensitivities in mice)2010
- Author(s)
  吉田竜介、大栗弾宏、上瀧将史、安尾敏明、堀尾奈央、安松啓子、實松敬介、重村憲徳、山本経之、Margolskee RF、二ノ宮裕三
- Organizer
  NEURO2010
- Place of Presentation
  神戸市、神戸コンベンションセンター
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] Suppressing effect of cyclodextrin to taste modifiers2010
- Author(s)
  Sanematsu K, Nakamura S, Ninomiya Y
- Organizer
  32thAchemS
- Place of Presentation
  St.Pete Beach, Florida, USA
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] Functional expression study of Tas1r1/Tas1R3 receptor variants associated with individual differences in human umami taste sensitivity2009
- Author(s)
  Shigemura N, Shirosaki S, Sanematsu K, Ogiwara Y, Kawai M, Yoshida R, Ninomiya Y
- Organizer
  第36回国際生理学会世界大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] 甘味抑制物質ギムネマ酸のヒト甘味受容体に対する相互作用部位2009
- Author(s)
  實松敬介、重村憲徳、上瀧将史、中村誠司、井元敏明、二ノ宮裕三
- Organizer
  第60回西日本生理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] Identification of the Interaction site for Gymnemic acid at the sweet taste receptor T1R2+T1R32009
- Author(s)
  Sanematsu K, Shigemura N, Jyotaki M, Nakamura S, Imoto T, Ninomiya Y
- Organizer
  31thAchemS
- Place of Presentation
  Sarasota, Florida, USA
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] Genetic and Moleculer Basis of Individual Differences in Human Umami Taste Perception2009
- Author(s)
  Shigemura N, Shirosaki S, Sanematsu K, Ogiwara Y, Kawai M, Yoshida R, Ninomiya Y
- Organizer
  31thAchemS
- Place of Presentation
  Sarasota, Florida, USA
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] ヒトうま味受容体T1R1/T1R3バリアントの機能解析2009
- Author(s)
  重村憲徳、城崎慎也、實松敬介、荻原葉子、河合美佐子、吉田竜介、二ノ宮裕三
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] 甘味受容体T1R2/T1R3に対するギムネマ酸相互作用部位の同定2009
- Author(s)
  實松敬介、重村憲徳、二ノ宮裕三
- Organizer
  第51回歯科基礎医学会総会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] ヒトT1R2/T1R3に対するギムネマ酸の相互作用の部位の同定2009
- Author(s)
  實松敬介、重村憲徳、上瀧将史、中村誠司、井元敏明、二ノ宮裕三
- Organizer
  第43回日本味と匂学会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] トリテルペン配糖体とヒト甘味受容体hT1R2/hT1R3の相互作用2008
- Author(s)
  實松敬介, 重村憲徳, 中村誠司, 井元敏明, 二ノ宮裕三
- Organizer
  第42回日本味と匂学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] Association between individual differences in umami sensitivity and genetic variations of Tlrs in human2008
- Author(s)
  Shigemura N, Islam AA, Shirosaki S, Sanematsu K, Ogiwara Y. Kawai M, Yoshida R, Ninomiya Y
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] 甘味受容体T1R2/T1R3とトリテルペン配糖体の相互作用2008
- Author(s)
  實松敬介, 重村憲徳, 二ノ宮裕三
- Organizer
  第50回歯科基礎医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] Modulation and transmission of sweet taste information for energy homeostasis2008
- Author(s)
  Ninomiya Y, Yoshida R, Murata Y, Yasumatsu K, Ohkuri T, Shirosaki S, Sanematsu K, Yasuo T, Nakamura Y, Shigemura N
- Organizer
  第15回ISOT
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] Interaction Between Triterpene Glycoside And Sweet Taste Receptor HT1R2+HT1R32008
- Author(s)
  Sanematsu K, Shigemura N, Imoto T, Ninomiya Y
- Organizer
  第15回ISOT
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] ヒトうま味感受性の多様性とうま味受容体遺伝子多型性との相関2008
- Author(s)
  重村憲徳, 城崎慎也, 實松敬介, Is1amAbu, 荻原葉子, 河合美佐子, 吉田竜介, 二ノ宮裕三
- Organizer
  第42回日本味と匂学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] Sweet-Suppressing Effect of Gymnemic Acid Examined by Using hTlR2+hTlR3 Assay in Transiently TransfectedHEK293 Cells2007
- Author(s)
  Sanematsu K, Shigemura N, Imoto T, Ninomiya Y
- Organizer
  日本味と匂学会第41回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] hT1R2+hT1R3強制発現系を用いたギムネマ酸の甘味抑制効果解析2007
- Author(s)
  實松敬介、重村憲徳、井元敏明、二ノ宮裕三
- Organizer
  第58回西日本生理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] 甘味およびうま味受容体機能解析2007
- Author(s)
  實松敬介、重村憲徳、二ノ宮裕三
- Organizer
  第49回歯科基礎医学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18109013
[Presentation] 腸管内分泌細胞の味覚感受性に対するレプチンの効果
- Author(s)
  上瀧将史、實松敬介、重村憲徳、二ノ宮裕三
- Organizer
  第64回西日本生理学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-25861759
[Presentation] The effect of gymnemic acids on taste and the recovery by r-cyclodextrin
- Author(s)
  Yasumatsu Y, Sanematsu K, Ninomiya Y
- Organizer
  第48回知覚コロキウム
- Place of Presentation
  日田
- Year and Date
  2015-03-06 – 2015-03-08
- Data Source
  KAKENHI-PROJECT-25861759
[Presentation] The molecular mechanisms involved in taste modifying effect of gymnemic acids examined by sweet-sensor
- Author(s)
  Sanematsu K, Yasumatsu Y, Shigemura N, Ninomiya Y
- Organizer
  第48回知覚コロキウム
- Place of Presentation
  日田
- Year and Date
  2015-03-06 – 2015-03-08
- Data Source
  KAKENHI-PROJECT-25861759
[Presentation] 甘味受容細胞の感受性抑制機構
- Author(s)
  實松敬介、二ノ宮裕三
- Organizer
  病態生理学会
- Place of Presentation
  大分
- Invited
- Data Source
  KAKENHI-PROJECT-23792128
[Presentation] Glucuronosyl group of gymnemic acids mainly interacts with the transmembrane domain of human T1R3 in sweet-suppressing effect.
- Author(s)
  Sanematsu K, Kusakabe Y, Shigemura N, Hirokawa T, Nakamura S, Imoto T, Ninomiya Y
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25861759
[Presentation] 甘味受容体T1R2/T1R3の分子メカニズム
- Author(s)
  實松敬介
- Organizer
  細胞センサーの分子機構・相互関係・ネットワーク研究会
- Place of Presentation
  岡崎
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25861759

1. SHIGEMURA Noriatsu (40336079)

# of Collaborated Projects: 8 results

# of Collaborated Products: 98 results
2. Takai Shingo (30760475)

# of Collaborated Projects: 6 results

# of Collaborated Products: 34 results
3. NINOMIYA Yuzo (50076048)

# of Collaborated Projects: 4 results

# of Collaborated Products: 76 results
4. Yasumatsu Keiko (50380704)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
5. YOSHIDA Ryusuke (60380705)

# of Collaborated Projects: 3 results

# of Collaborated Products: 38 results
6. 川端由子 (40906830)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. Toko Kiyoshi (50136529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OKI Eiji (70380392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OKAMOTO Tatsuro (80568626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SHIMIZU Kuniyoshi (20346836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HAYASHI Kenshi (50202263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ONODERA Takeshi (50336062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAHARA Yusuke (80585927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YATABE Rui (00735847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 岩槻健 (50332375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松井利郎 (20238942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 内田誠一 (70315125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 前原喜彦 (80165662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 広津崇亮 (70404035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 園田英人 (00465725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 岩田周介 (60780062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. 日下部裕子 (90353937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. TANAKA Mitsuru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 野村政壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sanematsu Keisuke 實松 敬介

SANEMATSU KEISUKE 實松 敬介

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Establishment of regulatory basis for nutrition and biological defense using taste receptorsPrincipal Investigator

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Dynamic Interaction Mechanisms of Taste ReceptorsPrincipal Investigator

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Elucidation of molecular, physiological, and pathological functions of taste receptors expressed throughout the bodyPrincipal Investigator

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Analysis of the sweet receptor as an energy sensorPrincipal Investigator

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Analysis for the fuction of sweet receptorPrincipal Investigator

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Analysis for interaction between sweet receptor and taste modifiersPrincipal Investigator

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Sanematsu Keisuke 實松敬介

SANEMATSU KEISUKE 實松敬介

[Book] 月刊化学Vol.78 No.8　甘味受容体の動的な活性化・不活性化メカニズムの解明ーー血糖値をコントロールできる甘味修飾物質の開発を目指して2023

[Book] 糖質・甘味のおいしさ評価と健康・調理・加工 (山野善正監修)　第4編3章ギムネマ酸の相互作用による甘味受容体抑制機構2022

[Book] 医学のあゆみ　各論：GPCR機能の新展開　【感覚】　味覚受容体2016

[Book] 医学のあゆみ Vol 256, No.5（GPCR機能の新展開【感覚】）2016