Kobayashi Eri 小林枝里

… Alternative Names

H. KOBAYASHI Eri 小林枝里

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Researcher Number	70634971
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 東北大学, 医学系研究科, 助教 2013 – 2016: 東北大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / 0905:Surgery of the organs maintaining homeostasis and related fields / General medical chemistry / Molecular biology Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 58020:Hygiene and public health-related: including laboratory approach
Keywords	Principal Investigator 妊娠高血圧症候群 / マクロファージ / Nrf2 / ChIP-seq / 炎症 / CRISPRスクリーニング / 転写因子 / ヒト胎盤幹細胞 / ヒトTS細胞 / エピゲノム … More / 転写抑制 / IL1b / IL6 / 状況特異的 / 遺伝子発現制御 / ストレス応答 / 転写制御 … More Except Principal Investigator オルガノイド / 胎盤幹細胞 / 胚着床不全 / 生殖補助医療（ART） / 3）低分子RNA（miRNA） / 低分子RNA(miRNA） / 低分子RNA（miRNA） / 胎盤 / 不妊治療 / 凍結胚移植 / 母体ー胎児間相互作用 / 母体-胎児間相互作用 / 妊娠高血圧症候群 / ヒト胎盤 Less

ヒト胎盤の発生・分化を調節する分子メカニズムと疾患の病態解明Principal Investigator
- Principal Investigator
  
  小林枝里
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tohoku University
ヒト胎盤形成のエピゲノム制御と母体－胎盤間分子シグナルコミュニケーションの理解
- Principal Investigator
  
  ARIMA TAKAHIRO
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tohoku University
An Empirical Study of the Effects of the Frozen Embryo Transfer Method on the Neurobehavioral Development of ART Births
- Principal Investigator
  
  miyauchi naoko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Tohoku University
Embryonic implantation organoids using human placental stem cells and challenges to treatment of implantation defects
- Principal Investigator
  
  ARIMA TAKAHIRO
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tohoku University
Epigenetic and gene expression analysis of cytotrophoblasts from term HDP placentaPrincipal Investigator
- Principal Investigator
  
  Kobayashi Eri
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0905:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tohoku University
ストレスおよび炎症応答転写因子の相互作用による転写活性化／抑制決定メカニズムPrincipal Investigator
- Principal Investigator
  
  小林枝里
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Nrf2-mediated anti-inflammation through transcriptional repression of proinflammatory cytokine genesPrincipal Investigator
- Principal Investigator
  
  H. KOBAYASHI Eri
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Tohoku University

All 2024 2023 2022 2021 2020 2017 2016 2014 Other

All Journal Article Presentation Book

[Book] 産婦人科の実際2023
- Author(s)
  柴田峻, 小林枝里, 有馬隆博
- Total Pages
  870
- Publisher
  金原出版(株)
- Data Source
  KAKENHI-PROJECT-21H04834
[Book] 産婦人科の実際2023
- Author(s)
  柴田峻, 小林枝里, 有馬隆博.
- Total Pages
  6
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-23K08838
[Book] トロホブラスト幹細胞と展開2021
- Author(s)
  小林枝里、岡江寛明、有馬隆博
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21H04834
[Book] トロホブラスト幹細胞と展開2021
- Author(s)
  小林枝里、岡江寛明、有馬隆博
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-20K22943
[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21H04834
[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-20K22943
[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21K10391
[Book] トロホブラスト幹細胞と展開2021
- Author(s)
  小林枝里、岡江寛明、有馬隆博
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21K19546
[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21K19546
[Journal Article] Trophoblast stem cell-based organoid models of the human placental barrier2024
- Author(s)
  Hori Takeshi、Okae Hiroaki、Shibata Shun、Kobayashi Norio、Kobayashi Eri H.、Oike Akira、Sekiya Asato、Arima Takahiro、Kaji Hirokazu
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1-1
- DOI
  10.1038/s41467-024-45279-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04852, KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-23K26514, KAKENHI-PLANNED-19H05757
[Journal Article] Modeling embryo-endometrial interface recapitulating human embryo implantation2024
- Author(s)
  Shibata Shun、Endo Shun、Nagai Luis A. E.、H. Kobayashi Eri、Oike Akira、Kobayashi Norio、Kitamura Akane、Hori Takeshi、Nashimoto Yuji、Nakato Ryuichiro、Hamada Hirotaka、Kaji Hirokazu、Kikutake Chie、Suyama Mikita、Saito Masatoshi、Yaegashi Nobuo、Okae Hiroaki、Arima Takahiro
- Journal Title
  
  Science Advances
  
  Volume: 10 Issue: 8
- DOI
  10.1126/sciadv.adi4819
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21H03803, KAKENHI-PROJECT-23K26514, KAKENHI-PLANNED-19H05757
[Journal Article] CRISPR screening in human trophoblast stem cells reveals both shared and distinct aspects of human and mouse placental development2023
- Author(s)
  Takanori Shimizu*, Akira Oike*, Eri H. Kobayashi*, Asato Sekiya, Norio Kobayashi, Shun Shibata, Hirotaka Hamada, Masatoshi Saito, Nobuo Yaegashi, Mikita Suyama, Takahiro Arima, and Hiroaki Okae. *T.S., A.O., and E.H.K. contributed equally to this work.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 51
- DOI
  10.1073/pnas.2311372120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08838, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PLANNED-19H05757
[Journal Article] The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells2022
- Author(s)
  Kobayashi Norio、Okae Hiroaki、Hiura Hitoshi、Kubota Naoto、Kobayashi Eri H.、Shibata Shun、Oike Akira、Hori Takeshi、Kikutake Chie、Hamada Hirotaka、Kaji Hirokazu、Suyama Mikita、Bortolin-Cavaill? Marie-Line、Cavaill? J?r?me、Arima Takahiro
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 3071-3071
- DOI
  10.1038/s41467-022-30775-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04852, KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21K19546, KAKENHI-PROJECT-22K15117, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05757
[Journal Article] Unique features and emerging in vitro models of human placental development.2020
- Author(s)
  Shun Shibata, Eri H Kobayashi, Norio Kobayashi, Akira Oike, Hiroaki Okae, Takahiro Arima.
- Journal Title
  
  Reprod Med Biol .
  
  Volume: 12 Issue: 4 Pages: 301-313
- DOI
  10.1002/rmb2.12347
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16135, KAKENHI-PROJECT-20K22615, KAKENHI-PROJECT-20K22943, KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-18K09216
[Journal Article] The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin.2017
- Author(s)
  Hidaka, T., Ogawa, E., Kobayashi, E.H., Suzuki, T., Funayama, R., Nagashima, T., Fujimura, T., Aiba, S., Nakayama, K., Okuyama, R., Yamamoto, M.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 18 Issue: 1 Pages: 64-73
- DOI
  10.1038/ni.3614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26461686, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-16K10143, KAKENHI-PROJECT-17K15590, KAKENHI-PROJECT-17H04240
[Journal Article] Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription.2016
- Author(s)
  Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, Tanaka N, Moriguchi T, Motohashi H, Nakayama K, Yamamoto M.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Issue: 1 Pages: 11624-11624
- DOI
  10.1038/ncomms11624
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K15228
[Presentation] 胎児-母体アセンブロイドを用いたin vitroにおけるヒト胚着床現象の再現2023
- Author(s)
  柴田峻, 遠藤俊, 大池輝, 小林枝里, Luis Augusto Eijy Nagai, 中戸隆一郎, 岡江寛明, 有馬隆博
- Organizer
  第41回日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-21H04834
[Presentation] Modeling Embryo Endometrial Interface Recapitulating Human Embryo Implantation2023
- Author(s)
  Shun Shibata, Luis A. E. Nagai, Akira Oike, Eri H. Kobayashi, Norio Kobayashi, Ryuichiro Nakato, Mikita Suyama, Hiroaki Okae, Takahiro Arima
- Organizer
  IHEC Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04834
[Presentation] マルチオミックス解析による妊娠高血圧症候群の胎盤特性2022
- Author(s)
  遠藤俊, 柴田峻, 大池輝, 小林枝里, 岡江寛明, 有馬隆博
- Organizer
  第30回日本胎盤学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04834
[Presentation] Activation of the miRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells2022
- Author(s)
  Kobayashi N, Okae H, Kaji H, Suyama M, Arima T
- Organizer
  IHEC2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04834
[Presentation] マルチオミックス解析による妊娠高血圧症候群の胎盤特性2022
- Author(s)
  遠藤俊, 柴田峻, 大池輝, 小林枝里, 岡江寛明, 有馬隆博.
- Organizer
  第30回日本胎盤学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19546
[Presentation] Activation of the miRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells2022
- Author(s)
  Kobayashi N, Okae H, Kaji H, Suyama M, Arima T
- Organizer
  IHEC2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19546
[Presentation] 転写因子Nrf2による炎症性サイトカイン遺伝子の転写阻害.2016
- Author(s)
  小林枝里, 鈴木隆史, 舟山亮, 長嶋剛史, 中山啓子, 山本雅之.
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台（仙台国際センター／東北大学川内北キャンパス）
- Year and Date
  2016-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08257
[Presentation] Air pollution activates Aryl hydrocarbon receptor in murine epidermis, leading to Atopic dermatitis-like pathologies.2016
- Author(s)
  Takanori Hidaka, Eri H Kobayashi, Takafumi Suzuki, and Masayuki Yamamoto.
- Organizer
  The 41st Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  仙台（仙台国際センター）
- Year and Date
  2016-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08257
[Presentation] Air pollution activates Aryl hydrocarbon receptor of un-differentiated keratinocytes, leading to Atopic dermatitis-like pathologies.2016
- Author(s)
  Takanori Hidaka, Eri H Kobayashi, Takafumi Suzuki, Masayuki Yamamoto.
- Organizer
  46th Annual Meeting of the European Society for Dermatological Research.
- Place of Presentation
  Munich, Germany
- Year and Date
  2016-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08257
[Presentation] Air pollution induces Atopic dermatitis-like pathologies via Aryl hydrocarbon receptor.2016
- Author(s)
  日高高徳, 小林枝里, 鈴木隆史, 山本雅之.
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台（仙台国際センター／東北大学川内北キャンパス）
- Year and Date
  2016-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08257
[Presentation] Myeloid-specific transcriptional regulation by Nrf22014
- Author(s)
  Eri H. Kobayashi, Takafumi Suzuki and Masayuki Yamamoto
- Organizer
  The Environmental Response IV
- Place of Presentation
  東北大学さくらホール、仙台
- Data Source
  KAKENHI-PROJECT-25840001
[Presentation] ストレス応答型転写因子Nrf2による炎症性サイトカイン遺伝子の発現抑制
- Author(s)
  小林枝里, 鈴木隆史, 舟山亮, 長嶋剛史, 中山啓子, 山本雅之
- Organizer
  「修飾シグナル病」若手ワークショップ
- Place of Presentation
  湯河原温泉「ホテルあかね」（神奈川）
- Year and Date
  2014-09-30 – 2014-10-02
- Data Source
  KAKENHI-PROJECT-25840001
[Presentation] 転写因子Nrf2による炎症性サイトカイン遺伝子の発現抑制
- Author(s)
  小林枝里, 鈴木隆史, 舟山亮, 長嶋剛史, 中山啓子, 山本雅之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25840001
[Presentation] Myeloid-specific transcriptional regulation by Nrf2
- Author(s)
  小林枝里, 鈴木隆史, 舟山亮, 長嶋剛史, 中山啓子, 山本雅之
- Organizer
  The Keap1/Nrf2 Pathway in Health and Disease
- Place of Presentation
  ケンブリッジ（英国）
- Year and Date
  2015-01-06 – 2015-01-08
- Data Source
  KAKENHI-PROJECT-25840001

1. 小林記緒 (10803885)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. ARIMA TAKAHIRO (80253532)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
3. 柴田峻 (40885670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. miyauchi naoko (60596162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. SUZUKI Norio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. SEKINE Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 舟山亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 堀武志

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 梶弘和

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 山本雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobayashi Eri 小林 枝里

H. KOBAYASHI Eri 小林 枝里

Research Projects

Research Products

Co-Researchers

ヒト胎盤の発生・分化を調節する分子メカニズムと疾患の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒト胎盤形成のエピゲノム制御と母体－胎盤間分子シグナルコミュニケーションの理解

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An Empirical Study of the Effects of the Frozen Embryo Transfer Method on the Neurobehavioral Development of ART Births

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Embryonic implantation organoids using human placental stem cells and challenges to treatment of implantation defects

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epigenetic and gene expression analysis of cytotrophoblasts from term HDP placentaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ストレスおよび炎症応答転写因子の相互作用による転写活性化／抑制決定メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Nrf2-mediated anti-inflammation through transcriptional repression of proinflammatory cytokine genesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 産婦人科の実際2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 産婦人科の実際2023

Author(s)

Total Pages

Publisher

Data Source

[Book] トロホブラスト幹細胞と展開2021

Author(s)

Total Pages

Publisher

Data Source

[Book] トロホブラスト幹細胞と展開2021

Author(s)

Total Pages

Publisher

Data Source

[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021

Author(s)

Total Pages

Publisher

Data Source

[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021

Author(s)

Total Pages

Publisher

Data Source

[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021

Author(s)

Total Pages

Kobayashi Eri 小林枝里

H. KOBAYASHI Eri 小林枝里