Koga Minori 古賀農人

Researcher Number	70744936
Other IDs
Affiliation (Current)	2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 精神科学, 講師
Affiliation (based on the past Project Information) *help	2017 – 2024: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 精神科学, 助教 2016: 北海道大学, 医学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Laboratory medicine Except Principal Investigator Basic Section 52030:Psychiatry-related / Basic Section 38050:Food sciences-related / Psychiatric science
Keywords	Principal Investigator 抑うつ症状 / 炎症 / ミクログリア / アストロサイト / エンドトキシン耐性 / リポ多糖 / マイクログリア / 精神疾患 / 生物学的マーカー / 脳型脂肪酸結合タンパク質 … More / バイオマーカー / うつ病 / 双極性障害 / 統合失調症 / 酸化ストレス / 脂肪酸結合タンパク質 … More Except Principal Investigator うつ病 / モデル動物 / ストレス応答回路 / 虐待 / HPA系 / 血液 / 双極性障害 / 気分障害 / 心的外傷後ストレス障害 / DNAメチル化修飾制御 / エピジェネティクス / CRISPR/dCas9 / 交通外傷 / PTSD / 酸化ストレス / ミクログリア / ミエリン鞘 / 認知機能障害 / CCL11 / ケモカイン / 神経炎症 / 統合失調症 / 摂食行動 / オペラント条件付け / 依存症 / 線条体 / 大脳基底核 / 過食 / 摂食障害 / エンケファリン / リピート異常伸長変異 / 臨床的促進現象 / YEATS2 / STARD7 / FAME3 / RAPGEF2 / TNRC6A / SAMD12 / 遺伝 / 良性成人型家族性ミオクローヌスてんかん / 脳組織 / 血漿 / L体 / D体 / アミノ酸 / うつ病モデルマウス / L体アミノ酸 / D体アミノ酸 / ストレス応答制御機構 / 視床下部‐下垂体‐副腎系 / マイクログリア / 幼少期ストレス / サイトカイン / Early Life Stress / 母子分離ストレス / 遺伝環境相互作用 / 遺伝子多型 / メチル化 / FKBP5 / 糖鎖 / 髄液 / グライコーム / メタボローム / うつ状態 / コルチゾール / バイオマーカー Less

Exploring the mechanisms through which stress encountered in the developmental stages affects the modulation of stress responses in PTSD.
- Principal Investigator
  
  戸田裕之
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  National Defense Medical College
Pathophysiology of cognitive dysfunction in schizophrenia focusing on the hypothesis of accelerated cerebral aging by CCL11
- Principal Investigator
  
  Kusumi Ichiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Hokkaido University
リポ多糖の前投与がミクログリアを介した抑うつ症状の発症を抑制するメカニズムの研究Principal Investigator
- Principal Investigator
  
  古賀農人
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  National Defense Medical College
Study on the Co-occurrence of Benign Adult Familial Myoclonic Epilepsy and Chronic Psychosis
- Principal Investigator
  
  Yoshino Aihide
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  National Defense Medical College
脳内オピオイド産生の計測制御による過食のメカニズムの解明
- Principal Investigator
  
  太田宏之
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  National Defense Medical College
Reserach of depression focusing on D-amino acids
- Principal Investigator
  
  NUMATA Shusuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  The University of Tokushima
Effects of developmental stress exposure on stress response regulation in depression and bipolar disorder
- Principal Investigator
  
  Hiroyuki Toda
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  National Defense Medical College
Biomarker research for depression stratified with HPA axis activity
- Principal Investigator
  
  NAKAGAWA Shin
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
  Hokkaido University
Study of brain-type fatty acid binding protein as a biomarker of psychiatric disorder for application to blood testPrincipal Investigator
- Principal Investigator
  
  Koga Minori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  National Defense Medical College
  Hokkaido University

All 2023 2022 2021 2020 2019 2018 2016

All Journal Article Presentation Book

[Book] CLINICAL NEUROSCIENCE Vol.39 (21年) 06月号ストレスと神経系. 酸化ストレスとメンタルストレスの関係. 精神疾患の病態解明への期待, p.7402021
- Author(s)
  古賀農人
- Total Pages
  124
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20K07958
[Journal Article] Identifying factors related to stigma toward psychiatric illness and mental health services and attitudes of help-seeking among Japan Ground Self-Defense Force members.2023
- Author(s)
  Yamazaki M, Nagamine M, Kitano M, Waki F, Edo N, Koga M, Tachimori H, Toda H.
- Journal Title
  
  J Psychiatr Res.
  
  Volume: 165 Pages: 241-247
- DOI
  10.1016/j.jpsychires.2023.07.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K11227, KAKENHI-PROJECT-23K24266
[Journal Article] Effect of interaction between a specific subtype of child abuse and the FKBP5 rs1360780 SNP on DNA methylation among patients with bipolar disorder2020
- Author(s)
  Saito Taku、Shinozaki Gen、Koga Minori、Tanichi Masaaki、Takeshita Shogo、Nakagawa Ryuichi、Nagamine Masanori、Cho Hyunkeun R.、Morimoto Yuji、Kobayashi Yasushi、Yoshino Aihide、Toda Hiroyuki
- Journal Title
  
  Journal of Affective Disorders
  
  Volume: 272 Pages: 417-422
- DOI
  10.1016/j.jad.2020.03.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07617
[Journal Article] Relationship between the subtypes of child abuse and affective temperaments: Comparison of depression and bipolar disorder patients and healthy controls using the reclassified Child Abuse and Trauma Scale2019
- Author(s)
  Saito Taku、Toda Hiroyuki、Inoue Takeshi、Koga Minori、Tanichi Masaaki、Takeshita Shogo、Nakagawa Ryuichi、Nagamine Masanori、Masuya Jiro、Tanabe Hajime、Shimizu Kunio、Kusumi Ichiro、Yoshino Aihide
- Journal Title
  
  Journal of Affective Disorders
  
  Volume: 257 Pages: 396-403
- DOI
  10.1016/j.jad.2019.06.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] Preconditioning of Lipopolysaccharide Improves Anxiety-Like Behavior and Brain Inflammation Associated with Chronic Corticosterone Exposure in Mice2023
- Author(s)
  Nakagawa R, Toda H, Koga M, Sato M, Nagamine M, Yoshino A
- Organizer
  2023SOBP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 恐怖記憶の記憶形成の初期段階にはミクログリアは必須ではない2023
- Author(s)
  佐藤真有実, 古賀農人, 中川隆一, 長峯正典, 浅井史穂, 太田宏之, 戸田裕之, 吉野相英
- Organizer
  第45回日本生物学的精神医学会総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] Inhibitory effect of preconditioning with lipopolysaccharide on the onset of anxiety and depressive-like behaviors2023
- Author(s)
  Koga M, Toda H, Nagamine M, Kinoshita M, Nakagawa R, Sato M, Mitsui Y, Yoshino A
- Organizer
  2023SOBP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 自衛官の精神疾患に対するスティグマの調査2023
- Author(s)
  山崎真之, 戸田裕之, 長峯正典, 北野誠人, 脇文子, 江戸直樹, 古賀農人, 立森久照, 吉野相英
- Organizer
  第 119 回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 東日本大震災に派遣された陸上自衛官の心的外傷後ストレス症状の軌跡とその関連要因－7年間の縦断研究－2023
- Author(s)
  斉藤拓, 戸田裕之, 古賀農人, 長峯正典
- Organizer
  第 22 回日本トラウマティック・ストレス学会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 神経炎症由来の精神障害に対するエンドトキシン耐性誘導による発症抑制効果におけるミクログリアの寄与2023
- Author(s)
  古賀農人, 戸田裕之, 中川隆一, 佐藤真有実, 長峯正典, 木下学, 中島弘幸, 浅井史穂, 茂木美千子, 吉野相英
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 食餌時間制限による減量では高脂質食摂取による不安様行動の発生が抑制されない2023
- Author(s)
  篠崎正紀, 戸田裕之, 浅井史穂, 吉野相英, 古賀農人
- Organizer
  第45回日本生物学的精神医学会総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 軽度外傷性脳損傷は心理的ストレスに対する精神障害発症の脆弱性を亢進する2023
- Author(s)
  古賀農人, 戸田裕之, 中川隆一, 佐藤真有実, 長峯正典, 佐藤泰司, 木下学, 浅井史穂, 吉野相英
- Organizer
  第45回日本生物学的精神医学会総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 慢性コルチコステロン暴露モデルマウスにおける中枢神経マクロファージの表現型の変化2023
- Author(s)
  中川隆一, 戸田裕之, 古賀農人, 長峯正典, 中島弘幸, 木下学, 佐藤真有美, 浅井史穂, 吉野相英
- Organizer
  第45回日本生物学的精神医学会総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 不安症状の病態形成においてマイクログリアは正にも負にも寄与する2022
- Author(s)
  古賀農人, 戸田裕之, 中川隆一, 佐藤真有実, 長峯正典, 浅井史穂, 三井由美, 吉野相英
- Organizer
  第 44 回日本生物学的精神医学会年会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 不安および抑うつ様行動発現に対する抑制効果を示すリポ多糖プレコンディショニングは脳内マクロファージの構成を変化させる2022
- Author(s)
  古賀農人, 戸田裕之, 中川隆一, 長峯正典, 中島弘幸, 木下学, 浅井史穂, 佐藤真有実, 松井茉莉江,三井由美, 吉野相英
- Organizer
  第 41 回躁うつ病の薬理・生化学的研究懇話会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 不安症状とマイクログリアの状態の関係2022
- Author(s)
  古賀農人, 戸田裕之, 中川隆一, 長峯正典, 浅井史穂, 三井由美, 吉野相英
- Organizer
  第 14 回日本不安症学会学術大会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 不安症状の病態形成においてマイクログリアは正にも負にも寄与する2022
- Author(s)
  古賀農人
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-21H02845
[Presentation] Effects of CSF1R inhibitor PLX3397 on reinforcement learning ability2022
- Author(s)
  太田裕之, 古賀農人, 中川隆一, 戸田裕之, 石塚俊晶
- Organizer
  第 95 回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] Trajectories of PTSD among First Responders after the 2011 Great East Japan Earthquake: a 7-year prospective cohort study2022
- Author(s)
  Van der Does F, Saito T, Nagamine M, Van der Wee N, Shigemura J, Yamamoto T, Takahashi Y, Koga M, Toda H, Yoshino A, Vermetten E, Giltay E:
- Organizer
  30th European Congress of Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 水素の摂取は神経炎症が引き起こす興味・関心の低下を抑制する2021
- Author(s)
  古賀農人、佐藤真有実、徳野慎一、中川隆一、長峯正典、浅井史穂、戸田裕之、吉野相英
- Organizer
  第10回分子状水素医学生物学会
- Data Source
  KAKENHI-PROJECT-20K07958
[Presentation] Lipopolysaccharideプレコンディショニングによる、マウスにおける慢性コルチコステロン暴露で認められる不安様行動、神経炎症の改善2021
- Author(s)
  中川隆一、古賀農人、佐藤真有実、戸田裕之、長峰正典、藤田真敬、吉野相英
- Organizer
  第43回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-20K07958
[Presentation] 精神障害の病態モデルマウスを用いたマイクログリアの異常と精神障害発症との因果関係解明の検討2021
- Author(s)
  古賀農人、戸田裕之、中川隆一、佐藤真有実、長峯正典、浅井史穂、三井由美、吉野相英
- Organizer
  第40回躁うつ病の薬理・生化学的研究懇話会
- Data Source
  KAKENHI-PROJECT-20K07958
[Presentation] 中枢神経系におけるエンドトキシン耐性のメカニズムの解明と炎症由来の精神障害発症予防への応用2021
- Author(s)
  古賀農人、戸田裕之、中川隆一、佐藤真有実、前沢友里、長峯正典、浅井史穂、三井由美、吉野相英
- Organizer
  第43回日本生物学的精神医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07958
[Presentation] リポポリサッカリドの事前投与は炎症由来の精神症状発症を抑制する2020
- Author(s)
  古賀農人、戸田裕之、長峯正典、木下学、浅井史穂、三井由美、吉野相英
- Organizer
  第50回日本神経精神薬理学会・第42回日本生物学的精神医学会・第４回日本精神薬学会総会・学術集会（NPBPPP 2020 合同年会）
- Data Source
  KAKENHI-PROJECT-20K07958
[Presentation] 幼少期ストレスは前頭前野のマイクログリアの質的変化ではなく数量的な変化を引き起こす2019
- Author(s)
  篠崎正紀, 梁木百合香, 古賀農人, 戸田裕之, 浅井史穂, 三井由美, 長峯正典, 吉野相英
- Organizer
  第38 回躁うつ病の薬理生化学的研究懇話会, 熱海
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] 双極性障害における幼少期ストレスとFKBP5 の一塩基多型、DNA メチル化との関係2019
- Author(s)
  斉藤拓, 戸田裕之, 古賀農人, 谷知正章, 竹下昇吾, 中川隆一, 長峯正典, 吉野相英
- Organizer
  第38 回躁うつ病の薬理生化学的研究懇話会, 熱海
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] Plasma brain-type fatty acid-binding protein is a potential candidate biomarker for psychiatric disorders2018
- Author(s)
  Minori Koga, Shin Nakagawa, Asumi Sato, Yumi Wakatsuki, Kan Kitagawa, Rie Kameyama, Niki Udo, Satoshi Asakura, Yutaka Fujii, Yuki Kako, Koki Ito, Nobuyuki Mitsui, Hisashi Narita, Kuniyoshi Toyoshima, Akiko Kato, Ichiro Kusumi
- Organizer
  Neuroscience 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19189
[Presentation] Immobilization stress enhances the hippocampal mRNA expression of FKBP5 in maternal separation rats2018
- Author(s)
  H. TODA, M. TANICHI, M. KOGA, T. SAITO, S. ENOMOTO, S. TAKESHITA, F. ASAI, Y. MITSUI, M. NAGAMINE, M. FUJITA, K. SHIMIZU, A. YOSHINO
- Organizer
  neuroscience 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] 自発運動促進と感覚刺激増加はシャトル箱法PTSD モデルラットの神経栄養因子とFKBP5 のmRNA 発現に異なる影響をもたらす2018
- Author(s)
  谷知　正章, 戸田　裕之, 清水　邦夫, 古賀　農人, 斉藤　拓, 榎本　真悟, 朴　秀賢, 浅井　史穂, 三井　由美, 長峯　正典, 澤村　岳人, 藤田　真敬, 吉野　相英
- Organizer
  第37 回躁うつ病の薬理生化学的研究懇話
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] Impacts on the stress reactivity in adult rats of maternal separation as early life stress2018
- Author(s)
  M. TANICHI, H. TODA, M. KOGA, T. SAITO, S. ENOMOTO, F. ASAI, Y. MITSUI, M. NAGAMINE, K. SHIMIZU, A. YOSHINO
- Organizer
  WFSBP2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] Serum brain-type fatty acid-binding protein level is elevated in response to mental stress2016
- Author(s)
  Minori Koga, Shin Nakagawa, Yumi Wakatsuki, Kan Kitagawa, Rie Kameyama, Niki Udo, Satoshi Asakura, Yutaka Fujii, Yuki Kako, Koki Ito, Nobuyuki Mitsui, Hisashi Narita, Kuniyoshi Toyoshima, Akiko Kato, Ichiro Kusumi
- Organizer
  Neuroscience 2016 Annual Meeting - Society for Neuroscience
- Place of Presentation
  San Diego (United States of America)
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19189
[Presentation] 精神的ストレスに対するバイオマーカーとしての血清中脳型脂肪酸結合タンパク質の検討2016
- Author(s)
  古賀農人、中川伸、若槻百美、北川寛、加藤亜紀子、久住一郎
- Organizer
  第 38回日本生物学的精神医学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-16K19189

1. Hiroyuki Toda (00610677)

# of Collaborated Projects: 4 results

# of Collaborated Products: 27 results
2. 太田宏之 (20535190)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. NAKAGAWA Shin (60360905)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. Kusumi Ichiro (30250426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. NUMATA Shusuke (10403726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Yoshino Aihide (20191629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山形弘隆 (10549934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 清水邦夫 (00531641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 朴秀賢 (60455665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 佐藤泰司 (10505267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 木下学 (70531391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 中島正裕 (70738103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 岩田朋大 (10860504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 立澤賢孝 (60276110)

# of Collaborated Projects: 1 results

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15. 守本祐司 (10449069)

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16. 今野歩 (40509048)

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17. 石川修平 (30880091)

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18. 橋本直樹 (40615895)

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19. 扇谷昌宏 (60636455)

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20. 豊巻敦人 (70515494)

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21. 新本弘 (00206335)

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22. 田辺肇 (60302361)

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23. 竹内崇 (70345289)

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24. 長峯正典 (70725217)

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25. 清住哲郎 (80818617)

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26. 田中良弘 (50533981)

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27. Kitaichi Yuji

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28. Hayasaka Takahiro

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Koga Minori 古賀 農人

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Exploring the mechanisms through which stress encountered in the developmental stages affects the modulation of stress responses in PTSD.

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Pathophysiology of cognitive dysfunction in schizophrenia focusing on the hypothesis of accelerated cerebral aging by CCL11

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リポ多糖の前投与がミクログリアを介した抑うつ症状の発症を抑制するメカニズムの研究Principal Investigator

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Study on the Co-occurrence of Benign Adult Familial Myoclonic Epilepsy and Chronic Psychosis

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脳内オピオイド産生の計測制御による過食のメカニズムの解明

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Reserach of depression focusing on D-amino acids

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Effects of developmental stress exposure on stress response regulation in depression and bipolar disorder

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Biomarker research for depression stratified with HPA axis activity

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Study of brain-type fatty acid binding protein as a biomarker of psychiatric disorder for application to blood testPrincipal Investigator

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[Book] CLINICAL NEUROSCIENCE Vol.39 (21年) 06月号 ストレスと神経系. 酸化ストレスとメンタルストレスの関係. 精神疾患の病態解明への期待, p.7402021

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[Journal Article] Identifying factors related to stigma toward psychiatric illness and mental health services and attitudes of help-seeking among Japan Ground Self-Defense Force members.2023

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[Journal Article] Effect of interaction between a specific subtype of child abuse and the FKBP5 rs1360780 SNP on DNA methylation among patients with bipolar disorder2020

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[Journal Article] Relationship between the subtypes of child abuse and affective temperaments: Comparison of depression and bipolar disorder patients and healthy controls using the reclassified Child Abuse and Trauma Scale2019

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[Presentation] Preconditioning of Lipopolysaccharide Improves Anxiety-Like Behavior and Brain Inflammation Associated with Chronic Corticosterone Exposure in Mice2023

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Koga Minori 古賀農人

[Book] CLINICAL NEUROSCIENCE Vol.39 (21年) 06月号ストレスと神経系. 酸化ストレスとメンタルストレスの関係. 精神疾患の病態解明への期待, p.7402021