Kobayashi Susumu 小林進

… Alternative Names

小林進コバヤシススム

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Researcher Number	70792836
Affiliation (based on the past Project Information) *help	2020 – 2024: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 分野長 2018: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 分野長
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Tumor biology / Medium-sized Section 50:Oncology and related fields Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 治療抵抗性 / 分子標的療法 / 非小細胞肺癌 / シグナル伝達 / チロシンキナーゼ阻害薬 / β-catenin / 肺がん / 薬剤耐性 / EGFR / 肺癌 … More / チロシンキナーゼ / 抗がん剤 / C/EBPα / 分化誘導 … More Except Principal Investigator 新規併用療法の開発戦略 / オミックス統合解析 / DNA損傷反応 / CDC7阻害剤TAK-931 / マルチオミックス解析 / 併用療法戦略 / がん治療薬 / 複製ストレス / TAK-931 / CDC7阻害剤 / 薬効・薬理研究 / バイオマーカー / トランスクリプトーム解析 / 橋渡し研究 / Drug Discovery / 低分子阻害剤 / CDC7キナーゼ / DNA複製ストレス Less

Role of Drug-Tolerant Persister cells in cancer treatmentPrincipal Investigator
- Principal Investigator
  
  小林進
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  National Cancer Center Japan
Development of a novel cell differentiation cancer therapyPrincipal Investigator
- Principal Investigator
  
  小林進
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  National Cancer Center Japan
Combination treatment with CDC7 inhibitor and DNA damage agents enhances antiproliferative activity in multiple preclinical models
- Principal Investigator
  
  Akihiro Ohashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Cancer Center Japan
Identification of the mechanisms underlying tumorigenesis by oncogenic tyrosine kinasesPrincipal Investigator
- Principal Investigator
  
  Kobayashi Susumu
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Home-Returning Researcher Development Research)
- Research Field
  
  Tumor biology
- Research Institution
  National Cancer Center Japan

All 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] 血液内科2020
- Author(s)
  江口基紀、小林進、南陽介
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-16K21746
[Book] 医学の歩み2020
- Author(s)
  小林進
- Total Pages
  5
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-16K21746
[Journal Article] HSP90 inhibition overcomes EGFR amplification-induced resistance to third-generation EGFR-TKIs2021
- Author(s)
  Watanabe S, Goto Y, Yasuda H, Kohno T, Motoi N, Ohe Y, Nishikawa H, Kobayashi SS, Kuwano K, Togashi Y.
- Journal Title
  
  Thoracic Cancer
  
  Volume: 12 Issue: 5 Pages: 631-42
- DOI
  10.1111/1759-7714.13839
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07036, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-16K21746, KAKENHI-PROJECT-17H06162
[Journal Article] Single-Cell Analyses Reveal Diverse Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer2021
- Author(s)
  Kashima Yukie、Shibahara Daisuke、Suzuki Ayako、Muto Kyoko、Kobayashi Ikei S.、Plotnick David、Udagawa Hibiki、Izumi Hiroki、Shibata Yuji、Tanaka Kosuke、Fujii Masanori、Ohashi Akihiro、Seki Masahide、Goto Koichi、Tsuchihara Katsuya、Suzuki Yutaka、Kobayashi Susumu S.
- Journal Title
  
  Cancer Research
  
  Volume: 81 Issue: 18 Pages: 4835-4848
- DOI
  10.1158/0008-5472.can-20-2811
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16879, KAKENHI-PROJECT-20H03541
[Journal Article] Combination treatment with a PI3K/Akt/mTOR pathway inhibitor overcomes resistance to anti-HER2 therapy in PIK3CA-mutant HER2-positive breast cancer cells2020
- Author(s)
  Fujimoto Yumi、Morita Tomoko Yamamori、Ohashi Akihiro、Haeno Hiroshi、Hakozaki Yumi、Fujii Masanori、Kashima Yukie、Kobayashi Susumu S.、Mukohara Toru
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 21762-21762
- DOI
  10.1038/s41598-020-78646-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07342, KAKENHI-PROJECT-19K23930, KAKENHI-PROJECT-19K23929, KAKENHI-PROJECT-16K21746
[Journal Article] Clinical Benefit of Tyrosine Kinase Inhibitors in Advanced Lung Cancer with EGFR-G719A and Other Uncommon EGFR Mutations.2020
- Author(s)
  Sehgal K, Rangachari D, VanderLaan PA, Kobayashi SS, Costa DB
- Journal Title
  
  Oncologist
  
  Volume: 26 Issue: 4 Pages: 281-287
- DOI
  10.1002/onco.13537
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Journal Article] Preclinical characterization of mobocertinib highlights the putative therapeutic window of this novel EGFR inhibitor to EGFR exon 20 insertion mutations2020
- Author(s)
  Vasconcelos PENS, Kobayashi IS, Kobayashi SS, Costa DB
- Journal Title
  
  JTO Clin Res Rep
  
  Volume: 2 Issue: 3 Pages: 100105-100105
- DOI
  10.1016/j.jtocrr.2020.100105
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Journal Article] Long-read sequencing for non-small-cell lung cancer genomes2020
- Author(s)
  Sakamoto Y, Xu L, Seki M, Yokoyama TT, Kasahara M, Kashima Y, Ohashi A, Shimada Y, Motoi N, Tsuchihara K, Kobayashi SS, Kohno T, Shiraishi Y, Suzuki A, Suzuki Y.
- Journal Title
  
  Genome Res
  
  Volume: 30 Issue: 9 Pages: 1243-57
- DOI
  10.1101/gr.261941.120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07036, KAKENHI-PROJECT-20H00545, KAKENHI-PROJECT-16K21746, KAKENHI-PROJECT-16H06279
[Journal Article] Alternative splicing of APOBEC3D generates functional diversity and its role as a DNA mutator2020
- Author(s)
  Takei Hisashi、Fukuda Hirofumi、Pan Gilbert、Yamazaki Hiroyuki、Matsumoto Tadahiko、Kazuma Yasuhiro、Fujii Masanori、Nakayama Sohei、Kobayashi Ikei S.、Shindo Keisuke、Yamashita Riu、Shirakawa Kotaro、Takaori-Kondo Akifumi、Kobayashi Susumu S.
- Journal Title
  
  International Journal of Hematology
  
  Volume: 112 Issue: 3 Pages: 395-408
- DOI
  10.1007/s12185-020-02904-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23930, KAKENHI-PROJECT-19H03502, KAKENHI-PROJECT-16K21746, KAKENHI-PROJECT-19K07591
[Journal Article] Osimertinib Plus Savolitinib Is Mediated by MET-D1228 and MET-Y1230 Mutations in EGFR-Mutated MET-Amplified Lung Cancer2020
- Author(s)
  Piper-Vallillo AJ, Halbert BT, Rangachari D, Kobayashi SS, Costa DB.
- Journal Title
  
  JTO Clinical and Research Reports
  
  Volume: 1 Pages: 100071-100071
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Journal Article] Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations2019
- Author(s)
  Ikemura S, Yasuda H, Matsumoto S, Kamada M, Hamamoto J, Masuzawa K, Kobayashi K, Manabe T, Arai D, Nakachi I, Kawada I, Ishioka K, Nakamura M, Namkoong H, Naoki K, Ono F, Araki M, Kanada R, Ma B, Hayashi Y, Mimaki S, Yoh K, Kobayashi SS, Kohno T, Okuno Y, Goto K, Tsuchihara K, Soejima K.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: Epub ahead of print Issue: 20 Pages: 10025-10030
- DOI
  10.1073/pnas.1819430116
- NAID
  120006799239
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09667, KAKENHI-PROJECT-19H03671, KAKENHI-PROJECT-18J12516, KAKENHI-PROJECT-16K21746
[Journal Article] Effects of gefitinib treatment on cellular uptake of extracellular vesicles in EGFR-mutant non-small cell lung cancer cells2019
- Author(s)
  Takenaka Tomoya、Nakai Shinya、Katayama Miku、Hirano Mami、Ueno Natsumi、Noguchi Kosuke、Takatani-Nakase Tomoka、Fujii Ikuo、Kobayashi Susumu S.、Nakase Ikuhiko
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 572 Pages: 118762-118762
- DOI
  10.1016/j.ijpharm.2019.118762
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06676, KAKENHI-PROJECT-16H02612, KAKENHI-PROJECT-20K20463, KAKENHI-PROJECT-18J15192, KAKENHI-PROJECT-16K21746, KAKENHI-PROJECT-17H00856
[Journal Article] Brief Report : EGFR-mutated lung cancers resistant to osimertinib through EGFR-C797S respond to 1st generation reversible EGFR inhibitors but eventually acquire EGFR-T790M/C797S in preclinical models and clinical samples2019
- Author(s)
  Rangachari D, To C, Shpilsky JE, VanderLaan PA, Kobayashi SS, Mushajiang M, Lau CJ, Paweletz CP, Oxnard GR, Jänne PA, Costa DB
- Journal Title
  
  J Thorac Oncol.
  
  Volume: 14 Issue: 11 Pages: 1995-2002
- DOI
  10.1016/j.jtho.2019.07.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Journal Article] Styryl quinazolinones and its ethynyl derivatives induce myeloid differentiation2019
- Author(s)
  Radhakrishnan S, Syed R, Takei H, Kobayashi IS, Nakamura E, Sultana F, Kamal A, Tenen DG, Kobayashi SS.
- Journal Title
  
  Bioorg Med Chem Lett.
  
  Volume: 29 Issue: 16 Pages: 2286-2289
- DOI
  10.1016/j.bmcl.2019.06.024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Journal Article] TAS6417/CLN-081 Is a Pan-Mutation-Selective EGFR Tyrosine Kinase Inhibitor with a Broad Spectrum of Preclinical Activity against Clinically Relevant EGFR Mutations.2019
- Author(s)
  Udagawa H, Hasako S, Ohashi A, Fujioka R, Hakozaki Y, Shibuya M, Abe N, Komori T, Haruma T, Terasaka M, Fujita R, Hashimoto A, Funabashi K, Yasuda H, Miyadera K, Goto K, Costa DB, Kobayashi SS.
- Journal Title
  
  Mol Cancer Res
  
  Volume: 17(11) Issue: 11 Pages: 2233-2243
- DOI
  10.1158/1541-7786.mcr-19-0419
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09667, KAKENHI-PROJECT-16K21746
[Journal Article] Transcription factor-based therapies for acute myeloid leukemia2018
- Author(s)
  小林進、武井寿史
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 7 Pages: 922-931
- DOI
  10.11406/rinketsu.59.922
- NAID
  130007430209
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21746
[Journal Article] Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBP α2018
- Author(s)
  Sridhar R, Takei H, Syed R, Kobayashi IS, Hui LB, Kamal A, Tenen DG, Kobayashi SS
- Journal Title
  
  Molecules
  
  Volume: 23 Issue: 8 Pages: 1938-1938
- DOI
  10.3390/molecules23081938
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Journal Article] Activity of brigatinib in the setting of alectinib resistance mediated by ALK-I1171S in ALK rearranged lung cancer.2018
- Author(s)
  Sehgal K, Peters MLB, VanderLaan PA, Rangachari D, Kobayashi SS, Costa DB.
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 23 Issue: 1 Pages: e1-e3
- DOI
  10.1016/j.jtho.2018.06.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Journal Article] EGFR exon 20 insertion mutations display sensitivity to Hsp90 inhibition in preclinical models and lung adenocarcinomas2018
- Author(s)
  Jorge S, Lucena-Araujo AR, Yasuda H, Piotrowska Z, Oxnard GR, Rangachari D, Huberman M, Sequist LV, Kobayashi SS, Costa DB
- Journal Title
  
  Clin Cancer Res
  
  Volume: 24 Issue: 24 Pages: 6548-6555
- DOI
  10.1158/1078-0432.ccr-18-1541
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] CENP-E inhibition generates micronucleus formation activating the cGAS-STING pathway in cancer cell.2021
- Author(s)
  Hakozaki Y., Kashima Y., Morita T.Y., Tanaka K, Kobayashi S.S. and Ohashi A.
- Organizer
  AACR Annual meeting, 2021.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03541
[Presentation] Property analysis of chromosomal instability adapted cells using multi omics approaches.2021
- Author(s)
  Morita T.M., Haeno H, Makinoshima H, Suzuki A, Kobayashi S.S. and Ohashi A.
- Organizer
  AACR Annual meeting, 2021.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03541
[Presentation] Multiomics approaches to clarify adaptive mechanisms of cancer cells to antiproliferative effects by chromosomal instability2020
- Author(s)
  Tomoko Y. Morita, Hiroshi Haeno, Hideki Makinoshima, Ayako Suzuki, Susumu S. Kobayashi, and Akihiro Ohashi.
- Organizer
  AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] A novel germline mutation in the non-coding region of BRCA2, c.-40+1 G>A, is associated with hereditary breast cancer.2020
- Author(s)
  Yumi Hakozaki, Yumi Fujimoto, Susumu S. Kobayashi, Mineko Ushiama, Yumie Hiraoka, Kenichi Harano, Takahiro Kogawa, Satoshi Fujii, Takeshi Kuwata, Teruhiko Yoshida, Akihiro Ohashi and Toru Mukohara
- Organizer
  AACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] Overview of drug resistance to TKI2020
- Author(s)
  小林進
- Organizer
  第61回日本肺癌学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] Resistance to EGFR Tyrosine Kinase Inhibitors2019
- Author(s)
  Susumu S. Kobayashi
- Organizer
  The 34th Nagoya International Cancer Treatment Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] Met/Rorl-β-catenin-Bcl-xL axis contributes to the emergence of drug-tolerant cells that evolve into resistant tumors in EGFR-mutant lung cancer.2019
- Author(s)
  Masanori Fujii, Sohei Nakayama, Naoki Akanuma, Gilbert Pan, Ikei S, Kobayashi, Hisashi Takei, Kohei Shimizu, Mariko Ando, Eunyoung Heo, Carol Gergis, Hiroyuki Inuzuka, Wenyi Wei, Daniel B. Costa, Susumu S. KObayashi.
- Organizer
  American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] Preclinical evaluation of TAS6417 as a highly effective, pan-mutation-selective EGFR tyrosine kinase inhibitor2019
- Author(s)
  Hibiki Udagawa, Shinichi Hasako, Akihiro Ohashi, Naomi Abe, Tomonori Haruma, Toshiharu Komori, Miki Terasaka, Ryoto Fujita, Kaoru Funabashi, Hiroyuki Yasuda, Kazutaka Miyadera, Koichi Goto, Daniel B. Costa and Susumu S. Kobayashi
- Organizer
  AACR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] Tumor Heterogeneity and Implications to Treatment Strategy with EGFR TKIs2019
- Author(s)
  小林進
- Organizer
  日本肺癌学会北海道支部会
- Invited
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] Multiple modalities of single cell analyses to evaluate the tumor microenvironment in clinical specimens2019
- Author(s)
  Yukie Kashima, Shota Fukuoka, Yosuke Togashi, Takahiro Kamada, Ayako Suzuki, Yoshiaki Nakamura, Kohei Shitara, Akihiro Ohashi, Taku Yoshida, Naofumi Taoka, Tatsuya Kawase, Teiji Wada, Kocihiro Inaki, Masataka Chihara, Yutaka Suzuki, Katsuya Tsuchihara, Susumu S Kobayashi, Hiroyoshi Nishikawa, Toshihiko Doi.
- Organizer
  AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] 治療抵抗性腫瘍の治療開発2019
- Author(s)
  小林進
- Organizer
  日本臨床腫瘍学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] Met/Rorl-β-catenin-Bcl-xL axis contributes to the emergence of drug-tolerant cells that evolve into resistant tumors in EGFR-mutant lung cancer2019
- Author(s)
  Masanori Fujii, Sohei Nakayama, Naoki Akanuma, Gilbert Pan, Ikei S. Kobayashi, Hisashi Takei, Kohei Shimizu, Mariko Ando, Eunyoung Heo, Carol Gergis, Hiroyuki Inuzuka, Wenyi Wei, Daniel B. Costa, and Susumu S. Kobayashi
- Organizer
  AACR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21746
[Presentation] Mechanisms and strategies to overcome resistance to tyrosine kinase inhibitors in lung cancer2018
- Author(s)
  Susumu S. Kobayashi
- Organizer
  日本がん学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K21746

1. Akihiro Ohashi (80835249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 影山俊一郎 (60644979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鹿島幸恵 (80831883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 濱田哲暢 (00322313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 田中広祐 (50894119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 柳下薫寛 (80781674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 犬塚博之 (20335863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 山下理宇 (10401259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 後藤功一 (90435719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 安田浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 向原徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 中瀬朋夏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 元井紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 藤井昌学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobayashi Susumu 小林 進

小林 進 コバヤシ ススム

Research Projects

Research Products

Co-Researchers

Role of Drug-Tolerant Persister cells in cancer treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel cell differentiation cancer therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Combination treatment with CDC7 inhibitor and DNA damage agents enhances antiproliferative activity in multiple preclinical models

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of the mechanisms underlying tumorigenesis by oncogenic tyrosine kinasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 血液内科2020

Author(s)

Total Pages

Publisher

Data Source

[Book] 医学の歩み2020

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] HSP90 inhibition overcomes EGFR amplification-induced resistance to third-generation EGFR-TKIs2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-Cell Analyses Reveal Diverse Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combination treatment with a PI3K/Akt/mTOR pathway inhibitor overcomes resistance to anti-HER2 therapy in PIK3CA-mutant HER2-positive breast cancer cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical Benefit of Tyrosine Kinase Inhibitors in Advanced Lung Cancer with EGFR-G719A and Other Uncommon EGFR Mutations.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preclinical characterization of mobocertinib highlights the putative therapeutic window of this novel EGFR inhibitor to EGFR exon 20 insertion mutations2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-read sequencing for non-small-cell lung cancer genomes2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Alternative splicing of APOBEC3D generates functional diversity and its role as a DNA mutator2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osimertinib Plus Savolitinib Is Mediated by MET-D1228 and MET-Y1230 Mutations in EGFR-Mutated MET-Amplified Lung Cancer2020

Author(s)

Journal Title

Data Source

[Journal Article] Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations2019

Author(s)

Kobayashi Susumu 小林進

小林進コバヤシススム