Mori Hitomi 森瞳美

Researcher Number	70795541
Affiliation (based on the past Project Information) *help	2021 – 2023: 九州大学, 医学研究院, 共同研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator バイオマーカー / 乳癌 / DHT / エストロゲン療法 / シングルセル解析 / エストロゲン受容体 / アロマターゼ阻害剤耐性 / ER陽性乳癌 Except Principal Investigator 腫瘍浸潤リンパ球（TIL） / MHCテトラマー解析 … More / 細胞医薬 / TIL / ペプチド / 体細胞性遺伝子変異 / ネオアンチゲン Less

Development of therapy-resistant breast cancer treatment using neoantigen-reactive lymphocytes
- Principal Investigator
  
  KUBO Makoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyushu University
Development of biomarkers of estrogen therapy for aromatase inhibitor-resistant recurrent breast cancerPrincipal Investigator
- Principal Investigator
  
  Mori Hitomi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] TP53 and/or BRCA1 Mutations Based on CtDNA Analysis as Prognostic Biomarkers for Primary Triple-Negative Breast Cancer2024
- Author(s)
  Arimura Akiko、Sakai Kazuko、Kaneshiro Kazuhisa、Morisaki Takafumi、Hayashi Saori、Mizoguchi Kimihisa、Yamada Mai、Kai Masaya、Ono Mayumi、Nishio Kazuto、Nakamura Masafumi、Kubo Makoto
- Journal Title
  
  Cancers
  
  Volume: 16 Issue: 6 Pages: 1184-1184
- DOI
  10.3390/cancers16061184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-23K27468
[Journal Article] Granzyme B Expression in the Tumor Microenvironment as a Prognostic Biomarker for Patients with Triple-Negative Breast Cancer2023
- Author(s)
  Mizoguchi Kimihisa、Kawaji Hitomi、Kai Masaya、Morisaki Takafumi、Hayashi Saori、Takao Yuka、Yamada Mai、Shimazaki Akiko、Osako Tomofumi、Arima Nobuyuki、Okido Masayuki、Oda Yoshinao、Nakamura Masafumi、Kubo Makoto
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 18 Pages: 4456-4456
- DOI
  10.3390/cancers15184456
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19532
[Journal Article] Immunological analysis of hybrid peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine.2023
- Author(s)
  Morisaki S, Onishi H, Morisaki T, Kubo M, Umebayashi M, Tanaka H, Koya N, Nakagawa S, Tsujimura K, Yoshimura S, Yew PY, Kiyotani K, Nakamura Y, Nakamura M, Kitazono T, Morisaki T.
- Journal Title
  
  Front. Immunol
  
  Volume: 14 Pages: 1223331-1223331
- DOI
  10.3389/fimmu.2023.1223331
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08715, KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-23K24422, KAKENHI-PROJECT-23K27469
[Journal Article] Identification and characterization of a proliferative cell population in estrogen receptor-positive metastatic breast cancer through spatial and single-cell transcriptomics2023
- Author(s)
  Yoshitake Ryohei、Mori Hitomi、Ha Desiree、Wu Xiwei、Wang Jinhui、Wang Xiaoqiang、Saeki Kohei、Chang Gregory、Shim Hyun Jeong、Chan Yin、Chen Shiuan
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2023.01.31.526403
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15571
[Journal Article] Significance of the Multi-gene Panel myRisk in Japan2022
- Author(s)
  HAYASHI SAORI、KUBO MAKOTO、MATSUZAKI SAWAKO、KAI MASAYA、MORISAKI TAKAFUMI、YAMADA MAI、KANESHIRO KAZUHISA、TAKAO YUKA、SHIMAZAKI AKIKO、NAGAYOSHI KINUKO、MIZUUCHI YUSUKE、NAKAMURA MASAFUMI
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Issue: 8 Pages: 4097-4102
- DOI
  10.21873/anticanres.15907
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-20K19173
[Journal Article] Lymph nodes as anti-tumor immunotherapeutic tool: intranodal tumor-specific antigen-pulsed dendritic cell vaccine immunotherapy2022
- Author(s)
  Morisaki T, Morisaki T, Kubo M, Morisaki S, Nakamura Y, Onishi H
- Journal Title
  
  Cancers
  
  Volume: 14(10) Issue: 10 Pages: 2438-2438
- DOI
  10.3390/cancers14102438
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-23K24422
[Journal Article] Genetic medicine is accelerating in Japan2022
- Author(s)
  Hayashi Saori、Kubo Makoto、Kaneshiro Kazuhisa、Kai Masaya、Yamada Mai、Morisaki Takafumi、Takao Yuka、Shimazaki Akiko、Shikada Sawako、Nakamura Masafumi
- Journal Title
  
  Breast Cancer
  
  Volume: 印刷中 Issue: 4 Pages: 659-665
- DOI
  10.1007/s12282-022-01342-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-20K19173
[Journal Article] Influence of Estrogen Treatment on ESR1+ and ESR1? Cells in ER+ Breast Cancer: Insights from Single-Cell Analysis of Patient-Derived Xenograft Models2021
- Author(s)
  Mori Hitomi、Saeki Kohei、Chang Gregory、Wang Jinhui、Wu Xiwei、Hsu Pei-Yin、Kanaya Noriko、Wang Xiaoqiang、Somlo George、Nakamura Masafumi、Bild Andrea、Chen Shiuan
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 24 Pages: 6375-6375
- DOI
  10.3390/cancers13246375
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15571
[Presentation] 乳癌患者とネオアンチゲン解析との関連性の検討2023
- Author(s)
  溝口公久, 森崎隆史, 甲斐昌也, 高尾由佳, 山田舞, 島﨑亜希子, 林早織, 茂地智子, 伊地知秀樹, 森崎隆, 吉住朋晴, 久保真, 中村雅史
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] 腫瘍遺伝子変異量(TMB):乳癌におけるバイオマーカーとしての意義2023
- Author(s)
  久保真, 森崎隆史, 溝口公久, 中垣環, 馬場英司, 中村雅史
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] 日本人乳癌患者の腸内細菌叢解析についての検討2023
- Author(s)
  山田舞, 久保真, 甲斐昌也, 森崎隆史, 溝口公久, 高尾由佳, 林早織, 島崎亜希子, 古賀艶可, 落合百合菜, 茂地智子, 伊地知秀樹, 吉住朋晴, 中村雅史
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] 乳癌シングルセル解析の魅力と今後の挑戦2022
- Author(s)
  森瞳美、Shiuan Chen、服部正見、本山健太郎、永井英司、中房祐司
- Organizer
  第30回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15571
[Presentation] シングルセル解析を用いたER陽性乳癌におけるESR1+およびESR1-細胞に対するエストロゲン治療の影響2022
- Author(s)
  森瞳美、Shiuan Chen、鬼塚哲、本山健太郎、永井英司、中房祐司
- Organizer
  第30回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15571
[Presentation] Influence of Estrogen Treatment on ESR1+ and ESR1－ Cells in ER+ Breast Cancer: Insights from Single-Cell Analysis of Patient-Derived Xenograft Models.2022
- Author(s)
  Hitomi Mori, Kohei Saeki, Gregory Chang, Jinhui Wang, Xiwei Wu, Pei-Yin Hsu, Noriko Kanaya, Xiaoqiang Wang, George Somlo, Masafumi Nakamura, Andrea Bild, Shiuan Chen
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15571
[Presentation] Efficacy of Gonadal steroids on aromatase inhibitor-resistant ER+ breast cancer: Insights from single-cell trajectory analysis of a patient-derived xenograft model2022
- Author(s)
  Hitomi Mori, Kohei Saeki, Gregory Chang, Jinhui Wang, Xiwei Wu, Noriko Kanaya, George Somlo, Shiuan Chen
- Organizer
  The 45th Annual San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15571
[Presentation] シングルセルRNA sequencingシークエンシングを用いたHER2陽性乳癌治療抵抗性の網羅的遺伝子解析2022
- Author(s)
  林早織, 久保真, 森瞳美, 甲斐昌也, 山田舞, 金城和寿, 森崎隆史, 高尾由佳, 島﨑亜希子, 中村雅史
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] HBOC診療の現状と課題2022
- Author(s)
  久保真, 鹿田佐和子, 甲斐昌也, 森崎隆史, 木村緑, 小川昌宣, 加藤聖子, 水内祐介, 中村雅史
- Organizer
  第28回日本遺伝性腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] アロマターゼ阻害剤(AI)耐性再発乳癌に対するエストロゲン療法のバイオマーカー開発2022
- Author(s)
  森瞳美、Shiuan Chen、鬼塚哲、本山健太郎、永井英司、中房祐司
- Organizer
  第 122 回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K15571
[Presentation] アロマターゼ阻害剤耐性再発乳癌に対する性ホルモンの有効性2022
- Author(s)
  森瞳美、Shiuan Chen、服部正見、本山健太郎、永井英司、中房祐司
- Organizer
  第23回ホルモンと癌研究会
- Data Source
  KAKENHI-PROJECT-21K15571
[Presentation] 1.Estrogen-mediated mechanisms in estrogen receptor-positive breast cancer at the single cell level2021
- Author(s)
  Hitomi Mori
- Organizer
  44th San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15571
[Presentation] Estrogen-induced cell cycle arrest as an unexpected outcome of aromatase inhibitor-resistance in ER+ breast cancer2021
- Author(s)
  森瞳美
- Organizer
  第２９回　乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15571
[Presentation] アロマターゼ阻害薬耐性ER+再発乳癌に対するエストロゲン療法2021
- Author(s)
  森瞳美
- Organizer
  第２９回　乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15571

1. KUBO Makoto (60403961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. 甲斐昌也 (10755242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. 森崎隆 (90291517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
4. 井手野昇 (90883421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ONISHI Hideya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Mori Hitomi 森 瞳美

Research Projects

Research Products

Co-Researchers

Development of therapy-resistant breast cancer treatment using neoantigen-reactive lymphocytes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of biomarkers of estrogen therapy for aromatase inhibitor-resistant recurrent breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] TP53 and/or BRCA1 Mutations Based on CtDNA Analysis as Prognostic Biomarkers for Primary Triple-Negative Breast Cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Granzyme B Expression in the Tumor Microenvironment as a Prognostic Biomarker for Patients with Triple-Negative Breast Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunological analysis of hybrid peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification and characterization of a proliferative cell population in estrogen receptor-positive metastatic breast cancer through spatial and single-cell transcriptomics2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significance of the Multi-gene Panel myRisk in Japan2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lymph nodes as anti-tumor immunotherapeutic tool: intranodal tumor-specific antigen-pulsed dendritic cell vaccine immunotherapy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic medicine is accelerating in Japan2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Influence of Estrogen Treatment on ESR1+ and ESR1? Cells in ER+ Breast Cancer: Insights from Single-Cell Analysis of Patient-Derived Xenograft Models2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 乳癌患者とネオアンチゲン解析との関連性の検討2023

Author(s)

Organizer

Data Source

[Presentation] 腫瘍遺伝子変異量(TMB):乳癌におけるバイオマーカーとしての意義2023

Author(s)

Organizer

Data Source

[Presentation] 日本人乳癌患者の腸内細菌叢解析についての検討2023

Author(s)

Organizer

Data Source

[Presentation] 乳癌シングルセル解析の魅力と今後の挑戦2022

Author(s)

Organizer

Data Source

[Presentation] シングルセル解析を用いたER陽性乳癌におけるESR1+およびESR1-細胞に対するエストロゲン治療の影響2022

Author(s)

Organizer

Data Source

[Presentation] Influence of Estrogen Treatment on ESR1+ and ESR1－ Cells in ER+ Breast Cancer: Insights from Single-Cell Analysis of Patient-Derived Xenograft Models.2022

Author(s)

Organizer

Data Source

Mori Hitomi 森瞳美