UCHIYAMA Makoto 内山聖

… Alternative Names

内田聖ウチヤママコト

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Researcher Number	80108050
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2005 – 2010: Niigata University, Institute of Medicine and Dentistry, Professor, 医歯学系, 教授 2001 – 2004: 新潟大学, 大学院・医歯学総合研究科, 教授 1992 – 2000: Niigata Univ. School of Med., Dept, Ped. Professor, 医学部, 教授 1990 – 1991: 大分医科大学, 医学部, 助教授 1988: Medical College of Oita; Associate professor, 医学部, 助教授 1987: 新潟大学, 医学部附属病院, 講師 1986: 新大, 医学部, 講師
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics Except Principal Investigator Pediatrics
Keywords	Principal Investigator 遺伝子治療 / Alport症候群 / Essential hypertension / 小児 / 本態性高血圧症 / gene therapy / Alport syndrome / electroporation / トランスジェニックマウス / Col4a4 … More / tenascin C / Sox9 / BMP / Msx2 / Msx1 / Blood pressure / Child / 高血圧 / 赤血球膜ナトリウム輸送 / 赤血球膜Na輸送 / Erythrocyte sodium transport / Family history of essential hypertension / ナトリウム摂取 / 血圧 / 本態性高血圧症家族歴 / bone marrow transplantation / Alport syndrome model mice / Col4a4ノックアウトマウス / 骨髄幹細胞移植 / Alportモデルマウス / Alpor症候群 / trancegenic mouse / enalapril / cyclosporin A / ミゾリビン / サイクロポリンA / エナラプリル / サイクロスポリンA / osteoblast / BMP-2 / 軟骨細胞 / 骨芽細胞 / COL4a3 / アデノウイルス / COL4a5 / アデノウイルスベクター / ノックアウトマウス / COL4a4 / Life style / Gene polymorphism / Angiotensinogen / 変異 / 遺伝子 / アンジオテンシノーゲン / Na transport / Ca intake / Ca pump / 尿中Ca / 血漿Ca / 高血圧家族歴 / 本態性高血圧 / Ca摂取 / 血小板Caポンプ受容体 / children / adrenergic receptor / Na pump receptor / digitalis / Cardiac failure / リンパ球交感神経受容体 / 赤血球膜Naポンプ受容体 / ジギタリス療法 / 交感神経受容体 / Naポンプ受容体 / うっ血性心不全 / 心房性ナトリウム利尿ペプチド / 尿中カテコラミン排泄 / 尿中カリクレイン排泄 / 家族歴 / ラット / 食塩 / Sall1遺伝子 / WT1遺伝子 / WT-1遺伝子 / 腎前駆細胞 / ES細胞 / Hox遺伝子 / Lim遺伝子 / ホメオボックス遺伝子 / IV型コラーゲン / 腎糸球体基底膜 / 尿中微量アルブミン / 尿中β_2ミンログロブリン / 尿中NAG / 腎症 / インスリン依存型糖尿病 … More Except Principal Investigator IV型コラーゲンα鎖 / NClドメイン / 変異 / コラーゲンドメイン / NC1ドメイン / HSP47 / ヘテロ三量体 / IV型コラーゲン / アルポート症候群 / Hoxa10 / Syndecan / MyoD / Lef1 / Bmp4 / Msx2 / Msx1 Less

Basic study for molecular mechanisms and novel therapy of Alport syndrome
- Principal Investigator
  
  KOBAYASHI Takehiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
胚性幹細胞を用いた腎前駆細胞の樹立および腎組織の再構築筑に関する研究Principal Investigator
- Principal Investigator
  
  内山聖
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Examination of Gene Therapy by Bone Marrow Derived Stem Cells to Alport SyndromePrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Makoto
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
IV型コラーゲンα5鎖およびα6鎖遺伝子の発現を調節するホメオボックス遺伝子の同定Principal Investigator
- Principal Investigator
  
  内山聖
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Basic studies for an effective therapy for Alport syndromePrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Makoto
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  NIIGATA UNIVERSITY
study of the function of a homeobox gene family Msx in osteochondrogenesisPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Makoto
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Alport症候群のモデルマウスの作成および遺伝子治療法の開発Principal Investigator
- Principal Investigator
  
  内山聖
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
ノックアウトマウスを用いたホメオテック遺伝子の標的遺伝子の同定
- Principal Investigator
  
  SATOKATA Ichiro
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Niigata University
Association analysis of the angiotensinogen gene polymorphism and life style with childhood essential hypertension.Principal Investigator
- Principal Investigator
  
  UCHIYAMA Makoto
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Pathophysiological role of platelet Ca pump in essential hypertensive children in relation to Ca intakePrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Makoto
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Measurements of erythrocyte Na pump receptor and lymphocyte adrenergic receptor in relation to digitalis-therapy in cardiac failurePrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Makoto
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University School of Medicine
  大分医科大学
インスリン依存型糖尿病における赤血球膜Na輸送異常の存在と腎症の進展に関する研究Principal Investigator
- Principal Investigator
  
  内山聖
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  大分医科大学
本態性高血圧症における赤血球膜Na輸送異常の家族集積性と小児期ナトリウム摂取の影響Principal Investigator
- Principal Investigator
  
  内山聖
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  大分医科大学
   Niigata University
Familial aggregation of abnormal sodium transport in erythrocytes :Effect of sodium intake in childhoodPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Makoto, 須田純子
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Dokkyo Medical University
  Medical College of Oita

All 2010 2008

All Journal Article

[Journal Article] Mutant-type α5(IV)collagen in a mild form of Alport syndrome has residual ability to form a heterotrimer.2010
- Author(s)
  Kobayashi T, Uchiyama M.
- Journal Title
  
  Pediatric Nephrology 25
  
  Pages: 1169-1172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Journal Article] Effect of HSP47 expression levels on heterotrimer formation among type IV collagen α3, α4 and α5 chains.2010
- Author(s)
  Kobayashi T, Uchiyama M.
- Journal Title
  
  Biomedical Research 31
  
  Pages: 371-377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Journal Article] Mutational analysis of type IV collagen α5 chain, with respect to heterotrimer formation.2008
- Author(s)
  Kobayashi T, Kakihara T, Uchiyama M.
- Journal Title
  
  Biochemical and Biophysical Research Communications 366
  
  Pages: 60-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273

1. SATOKATA Ichiro (70170800)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. ITO Tatsuo (40345533)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. HAYAKAWA Hiroshi (90208603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HASHIMOTO Naoshi (90208455)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KOBAYASHI Takehiro (90311670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. IKEZUMI Yohei (70361897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANAKA Atsushi (60221389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 五味崇行 (70183358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中西真人 (10172355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 須田純子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

UCHIYAMA Makoto 内山 聖

内田 聖 ウチヤマ マコト

Research Projects

Research Products

Co-Researchers

Basic study for molecular mechanisms and novel therapy of Alport syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

胚性幹細胞を用いた腎前駆細胞の樹立および腎組織の再構築筑に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Examination of Gene Therapy by Bone Marrow Derived Stem Cells to Alport SyndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IV型コラーゲンα5鎖およびα6鎖遺伝子の発現を調節するホメオボックス遺伝子の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic studies for an effective therapy for Alport syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

study of the function of a homeobox gene family Msx in osteochondrogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Alport症候群のモデルマウスの作成および遺伝子治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ノックアウトマウスを用いたホメオテック遺伝子の標的遺伝子の同定

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Association analysis of the angiotensinogen gene polymorphism and life style with childhood essential hypertension.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathophysiological role of platelet Ca pump in essential hypertensive children in relation to Ca intakePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Measurements of erythrocyte Na pump receptor and lymphocyte adrenergic receptor in relation to digitalis-therapy in cardiac failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

インスリン依存型糖尿病における赤血球膜Na輸送異常の存在と腎症の進展に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

本態性高血圧症における赤血球膜Na輸送異常の家族集積性と小児期ナトリウム摂取の影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

UCHIYAMA Makoto 内山聖

内田聖ウチヤママコト