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UCHIYAMA Makoto  内山 聖

ORCIDConnect your ORCID iD *help
… Alternative Names

内田 聖  ウチヤマ マコト

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Researcher Number 80108050
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2005 – 2010: Niigata University, Institute of Medicine and Dentistry, Professor, 医歯学系, 教授
2001 – 2004: 新潟大学, 大学院・医歯学総合研究科, 教授
1992 – 2000: Niigata Univ. School of Med., Dept, Ped. Professor, 医学部, 教授
1990 – 1991: 大分医科大学, 医学部, 助教授
1988: Medical College of Oita; Associate professor, 医学部, 助教授
1987: 新潟大学, 医学部附属病院, 講師
1986: 新大, 医学部, 講師
Review Section/Research Field
Principal Investigator
Pediatrics / Pediatrics
Except Principal Investigator
Pediatrics
Keywords
Principal Investigator
本態性高血圧症 / 小児 / Essential hypertension / Alport症候群 / 遺伝子治療 / 赤血球膜Na輸送 / 赤血球膜ナトリウム輸送 / 高血圧 / Child / Blood pressure … More / Msx1 / Msx2 / BMP / Sox9 / tenascin C / Col4a4 / トランスジェニックマウス / electroporation / Alport syndrome / gene therapy / インスリン依存型糖尿病 / 腎症 / 尿中NAG / 尿中β_2ミンログロブリン / 尿中微量アルブミン / 腎糸球体基底膜 / IV型コラーゲン / ホメオボックス遺伝子 / Lim遺伝子 / Hox遺伝子 / ES細胞 / 腎前駆細胞 / WT-1遺伝子 / WT1遺伝子 / Sall1遺伝子 / 食塩 / ラット / 家族歴 / 尿中カリクレイン排泄 / 尿中カテコラミン排泄 / 心房性ナトリウム利尿ペプチド / うっ血性心不全 / Naポンプ受容体 / 交感神経受容体 / ジギタリス療法 / 赤血球膜Naポンプ受容体 / リンパ球交感神経受容体 / Cardiac failure / digitalis / Na pump receptor / adrenergic receptor / children / 血小板Caポンプ受容体 / Ca摂取 / 本態性高血圧 / 高血圧家族歴 / 血漿Ca / 尿中Ca / Ca pump / Ca intake / Na transport / アンジオテンシノーゲン / 遺伝子 / 変異 / Angiotensinogen / Gene polymorphism / Life style / COL4a4 / ノックアウトマウス / アデノウイルスベクター / COL4a5 / アデノウイルス / COL4a3 / 骨芽細胞 / 軟骨細胞 / BMP-2 / osteoblast / サイクロスポリンA / エナラプリル / サイクロポリンA / ミゾリビン / cyclosporin A / enalapril / trancegenic mouse / Alpor症候群 / Alportモデルマウス / 骨髄幹細胞移植 / Col4a4ノックアウトマウス / Alport syndrome model mice / bone marrow transplantation / 本態性高血圧症家族歴 / 血圧 / ナトリウム摂取 / Family history of essential hypertension / Erythrocyte sodium transport … More
Except Principal Investigator
Msx1 / Msx2 / Bmp4 / Lef1 / MyoD / Syndecan / Hoxa10 / アルポート症候群 / IV型コラーゲン / ヘテロ三量体 / HSP47 / NC1ドメイン / コラーゲンドメイン / 変異 / NClドメイン / IV型コラーゲンα鎖 Less
  • Research Projects

    (14 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (10 People)
  •  Basic study for molecular mechanisms and novel therapy of Alport syndrome

    • Principal Investigator
      KOBAYASHI Takehiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Niigata University
  •  胚性幹細胞を用いた腎前駆細胞の樹立および腎組織の再構築筑に関する研究Principal Investigator

    • Principal Investigator
      内山 聖
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Niigata University
  •  Examination of Gene Therapy by Bone Marrow Derived Stem Cells to Alport SyndromePrincipal Investigator

    • Principal Investigator
      UCHIYAMA Makoto
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Niigata University
  •  IV型コラーゲンα5鎖およびα6鎖遺伝子の発現を調節するホメオボックス遺伝子の同定Principal Investigator

    • Principal Investigator
      内山 聖
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Niigata University
  •  Basic studies for an effective therapy for Alport syndromePrincipal Investigator

    • Principal Investigator
      UCHIYAMA Makoto
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      NIIGATA UNIVERSITY
  •  study of the function of a homeobox gene family Msx in osteochondrogenesisPrincipal Investigator

    • Principal Investigator
      UCHIYAMA Makoto
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Niigata University
  •  Alport症候群のモデルマウスの作成および遺伝子治療法の開発Principal Investigator

    • Principal Investigator
      内山 聖
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pediatrics
    • Research Institution
      Niigata University
  •  ノックアウトマウスを用いたホメオテック遺伝子の標的遺伝子の同定

    • Principal Investigator
      SATOKATA Ichiro
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  Association analysis of the angiotensinogen gene polymorphism and life style with childhood essential hypertension.Principal Investigator

    • Principal Investigator
      UCHIYAMA Makoto
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Niigata University
  •  Pathophysiological role of platelet Ca pump in essential hypertensive children in relation to Ca intakePrincipal Investigator

    • Principal Investigator
      UCHIYAMA Makoto
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Niigata University
  •  Measurements of erythrocyte Na pump receptor and lymphocyte adrenergic receptor in relation to digitalis-therapy in cardiac failurePrincipal Investigator

    • Principal Investigator
      UCHIYAMA Makoto
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Niigata University School of Medicine
      大分医科大学
  •  インスリン依存型糖尿病における赤血球膜Na輸送異常の存在と腎症の進展に関する研究Principal Investigator

    • Principal Investigator
      内山 聖
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      大分医科大学
  •  本態性高血圧症における赤血球膜Na輸送異常の家族集積性と小児期ナトリウム摂取の影響Principal Investigator

    • Principal Investigator
      内山 聖
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      大分医科大学
      Niigata University
  •  Familial aggregation of abnormal sodium transport in erythrocytes :Effect of sodium intake in childhoodPrincipal Investigator

    • Principal Investigator
      UCHIYAMA Makoto, 須田 純子
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Dokkyo Medical University
      Medical College of Oita

All 2010 2008

All Journal Article

  • [Journal Article] Mutant-type α5(IV)collagen in a mild form of Alport syndrome has residual ability to form a heterotrimer.2010

    • Author(s)
      Kobayashi T, Uchiyama M.
    • Journal Title

      Pediatric Nephrology 25

      Pages: 1169-1172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591273
  • [Journal Article] Effect of HSP47 expression levels on heterotrimer formation among type IV collagen α3, α4 and α5 chains.2010

    • Author(s)
      Kobayashi T, Uchiyama M.
    • Journal Title

      Biomedical Research 31

      Pages: 371-377

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591273
  • [Journal Article] Mutational analysis of type IV collagen α5 chain, with respect to heterotrimer formation.2008

    • Author(s)
      Kobayashi T, Kakihara T, Uchiyama M.
    • Journal Title

      Biochemical and Biophysical Research Communications 366

      Pages: 60-65

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591273
  • 1.  SATOKATA Ichiro (70170800)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  ITO Tatsuo (40345533)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  HAYAKAWA Hiroshi (90208603)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  HASHIMOTO Naoshi (90208455)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  KOBAYASHI Takehiro (90311670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  IKEZUMI Yohei (70361897)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TANAKA Atsushi (60221389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  五味 崇行 (70183358)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  中西 真人 (10172355)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  須田 純子
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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