NIINOBE Michio 新延道夫

Researcher Number	80135748
Affiliation (based on the past Project Information) *help	1996 – 2001: Institute for Protein Research, Osaka University, Associate Professor, たんぱく質研究所, 助教授 1996 – 2001: Osaka University, Institute for Protein Research, Associate Professor, 蛋白質研究所, 助教授 1998: 大阪大学, 蛋白研究所, 助教授 1995: 大阪大学, たんぱく質研究所, 助手 1995: 大阪大学, 蛋白質研究所, 助手 … More 1995: 大阪大学, 蛋白質研究所・蛋白質機能制御部門, 助手 1991 – 1992: Institute for Protein Research, Osaka University, instructor, たんぱく質研究所, 助手 1991: Institute for Protein Research, Osaka University, 蛋白質研究所, 助手 1990: 大阪大学, たんぱん質研究所 1989: 大阪大学, たんぱく質研究所, 助手 1986 – 1989: Inst. for Protein Res. Osaka Univ., 蛋白質研究所, 助手 1987: Osaka University, 蛋白質研究所・機能制御部門, 助手 1986: 大阪大学, 蛋白質研究所・蛋白質機能制御部門, 助手 1986: 大阪大学, 蛋白質研究所機能制御部門, 助手 Less
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / General medical chemistry Except Principal Investigator Neurochemistry/Neuropharmacology / Thoracic surgery / 医学一般 / 分子遺伝学・分子生理学 / Pathological medical chemistry
Keywords	Principal Investigator エンドサイトーシス / ラット交感神経節細胞 / アミロイド前駆体蛋白質 / アルツハイマー病 / シナプス小胞 / Endocytosis / イノシトールポリリン酸 / シナプトタグミン / IP_4 / IP_3 … More / Serine-threonine Kinase / Caenorhabditis elegans / Apoptosis / Caspase-3 / NT-2 Cell / Synaptic Vesicle / Amyloid Precursor Protein / アデノウィスルベクター / カスパーゼ / セリン・スレオニンキナーゼ様蛋白質 / セリン・スレオニンキナーゼ / 線虫 / アポトーシス / カスパーゼ3 / NT-2細胞 / 再取り込みシグナル / amyloid precursor protein / Alzheimeis disease / clathrin assembly protein / inositol polyphosphate / endocytosis / exocytosis / synaptic vesicle / synaptotagmin / イノシトール6リン酸 / シナプス連絡 / クラスリン集合蛋白質 / エキソサイトーシス / Neurotransmitter Release / Inositol Polyphosphate / Synaptotagmin / 神経伝達物質放出 / IP_4 Binding Protein / IP_3 Receptor / Ca^<2+>チャンネル / IP_3受容体, / IP_4受容体 / IP_4結合蛋白質 / IP_4BPI / アルドラーゼ / IP_4BP1 / IP_3受容体 … More Except Principal Investigator Necdin / E2F1 / ニューロン / Cell cycle / ゲノムインプリンティング / 細胞周期 / cerebellum / jimpy / E2F / Apoptosis / 細胞分裂終了 / アポトーシス / p53 / Neurons / プラダー・ウイリ症候群 / 胚性がん細胞 / アデノウイルスベクター / APP / morphogenesis / endoplasmic reticulum / calcium channel / mouse mutant / P400蛋白質 / シナプス形成 / アルツハイマー病 / 遺伝子導入 / 形態形成 / 小脳 / 神経発生 / ミエリン塩基性蛋白質 / oligodendrocyte / ミエリンプロテオリピド蛋白質 / オリゴデンドロサイト / ジンピー / Blood / Camplement Platelet / Coagulation / Biocanpatiblility / 生体応答性 / 血小板系 / 補体系 / 凝固系 / 生体適合性 / myelin basic protein (MBP) / myelin / myelin basic protein / jimpy mutant / protelipid protein / 遺伝子再構成 / プロモーター活性 / mylin deficient(mld) / プロテオリピド蛋白質 / myelin deficient(mld) / Control Release / Anticoagulant / セグメント化ポリウレタン / 抗血栓性 / 生理活性物質 / 人工臓器 / 徐放性 / Transcription repressor / Nuclear Matrix / Terminal differentiation / 細胞死 / 分化 / 神経幹細胞 / 転写抑制因子 / 核マトリックス / 最終分化 / Genome imprinting / Proteasome / Neuron / プロテアソーム / Genomic imprinting / Prader-Willi syndrome / Retinoblastoma protein / Cell differentiation / 神経分化 / アデノウィルスベクター / 核蛋白質 / necdin / がん抑制遺伝子 / プラダー・ウィリ症候群 / レチノブラストーマ蛋白質 / 細胞分化 / gene transfer / brain / neurodegeneration / adenovirus vector / neurons / amyloid protein / Alzheimer's disease / アデノウイルス / 発現制御 / 培養細胞 / 脳病理 / 脳 / 神経変性 / アミロイドβ蛋白質 / InsP_3 (inositol trisphosphate) or IP_3 / InsP_3 receptor or IP_3 receptor / in situ ハイブリダイゼ-ション / 発生と分化 / 中枢神経系 / 小胞体 / カルシウムチャネル / 小脳プルキン工細胞 / 染色体マッピング / InsP_3レセプタ- / InsP_3(inositol trisphosphate) / InsP_3 receptor / cAMP依存性蛋白質リン酸化酵素 / 膜貫通蛋白質 / プルキンI細胞 / カルスペクチン / sraggererミュータントマウス / ブルキンエ細胞 / peptide antigen / SP6 transcription / oligonucleotide directed site-specific mutagenesis / MBP expression / Shiverer / neuron-specific protein / 【P_(400)】protein / シナプス伝達 / アミロイド蛋白前駆体 / 行動異常 / Zic / 神経堤 / 遺伝子タ-デティング / 神経上皮 / 組織特異的遺伝子発現 / 転写因子 / 背腹軸 / ライアノジンレセプタ- / IP_3(イノシト-ル3リン酸)受容体 / 遺伝子的組換え / アンチセンスRNA / ミエリン形成不全症 Less

Research Projects
(22 results)
Co-Researchers
(20 People)

Regulatory mechanisms of neuronal differentiation and death by necdin
- Principal Investigator
  
  YOSHIKAWA Kazuaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Analysis of the Functions in Synapse of Amyloid Precursor ProteinPrincipal Investigator
- Principal Investigator
  
  NIINOBE Michio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
アルツハイマー病誘因蛋白質のシナプス伝達変調作用の分子的・可視的・電気生理学的解析
- Principal Investigator
  
  MOCHIDA Sumiko
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Medical University
Studies on generation and differentiation of central neurons in association with postmitotic mechanisms
- Principal Investigator
  
  YOSHIKAWA Kazuaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Involvement of Inositol Polyphosphates in Neurotermuinal Mechanism and Analysis of the Molecular MechanismPrincipal Investigator
- Principal Investigator
  
  NIINOBE Michio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
哺乳類小脳をモデル系とした神経回路網形成の分子機構の解明
- Principal Investigator
  
  有賀純
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Institute of Physical and Chemical Research
Molecular cell-biological studies on differentiation and mitotic arrest of brain neurons
- Principal Investigator
  
  YOSHIKAWA Kazuaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
哺乳類小脳をモデル系とした中枢シナプス形成の分子機構の解明
- Principal Investigator
  
  ARUGA Jun
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Institute of Physical and Chemical Research
Establishment of Alzheimer model cell system and its application to therapeutics
- Principal Investigator
  
  YOSHIKAWA Kazuaki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Molecular Mechanism on the Block of Neurotransmitter Release with Inositol PolyphosphatesPrincipal Investigator
- Principal Investigator
  
  NIINOBE Michio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Molecular genetic studies on mammalian brain morphogenesis
- Principal Investigator
  
  MIKOSHIBA Katsuhiko
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Institute for Protein Research, Osaka University
Involvement and the Molecular Mechanisms of Inositol-1.4.5 Trisphosphate Receptor in the Expression of Neuronal FunctionsPrincipal Investigator
- Principal Investigator
  
  NIINOBE Michio
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
運動失調症ミュ-タントによる障害機構の分子生物学的研究
- Principal Investigator
  
  MIKOSHIBA Katsuhiko
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
小脳ミュ-タントマウスを用いたシナプスにおけるインパルス伝達機構の解析
- Principal Investigator
  
  御子柴克彦
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
運動失調症シュータントによる障害機構の分子生物学的研究
- Principal Investigator
  
  御子柴克彦
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
運動失調症ミュータントによる障害機構の分子生物学的研究
- Principal Investigator
  
  御子柴克彦
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Functional restoration of genetically inherited neuronal disorder - Molecular biological approach using heriditary mutant mice -
- Principal Investigator
  
  MIKOSHIBA Katsuhiko
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  医学一般
- Research Institution
  Osaka University
小脳のプルキンエ細胞に内在するシナプス形成因子の分子生物学的研究
- Principal Investigator
  
  御子柴克彦
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Osaka University
脳発育障害突然変異マウスの神経科学的研究
- Principal Investigator
  
  御子柴克彦
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Osaka University
Studies of neural cell specific gene expression by neurological mutant mice.
- Principal Investigator
  
  MIKOSHIBA Katsuhiko
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Institute for Protein Research,Osaka University.
Multiphasic studies on mechamistic asrects of Biocompatiblity of Materials used far Cardiouascular Devices
- Principal Investigator
  
  MATSUDA Takehisa
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  National cardiovascular Center
Development of Control-Release Materials and Its Applications to Cardiovascular Artificial Organs
- Principal Investigator
  
  MATSUDA Takehisa
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Thoracic surgery
- Research Institution
  National Cardiovascular Center

1. MIKOSHIBA Katsuhiko (30051840)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. OKANO Hideyuki (60160694)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. IKENAKA kazuhiro (00144527)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. ARUGA Jun (10232076)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. YOSHIKAWA Kazuaki (30094452)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. UETSUKI Taichi (20260309)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. TANIURA Hideo (80263325)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. MOCHIDA Sumiko (30096341)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MATSUDA Takehisa (60142189)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. IWATA Hiroo (30160120)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. HAYASHI Yokichi (70173044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIKI Naomasa (40094445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ADACHI Seiji (60151073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKANO Hisateru (60028595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. AKUTSU Tetsuzo (40150221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SAKAKIBARA Izumi (90153866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HAYASHI Ryosuke (00173047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KATOH Hisao (80029959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 前田信明 (90202308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. GUENET Jean-Louis

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NIINOBE Michio 新延 道夫

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Analysis of the Functions in Synapse of Amyloid Precursor ProteinPrincipal Investigator

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Involvement of Inositol Polyphosphates in Neurotermuinal Mechanism and Analysis of the Molecular MechanismPrincipal Investigator

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Molecular Mechanism on the Block of Neurotransmitter Release with Inositol PolyphosphatesPrincipal Investigator

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Involvement and the Molecular Mechanisms of Inositol-1.4.5 Trisphosphate Receptor in the Expression of Neuronal FunctionsPrincipal Investigator

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NIINOBE Michio 新延道夫