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KAWAHARA Yasuhiro
川原 康洋
Connect your ORCID iD
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Alternative Names
川原 康弘
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Researcher Number
80169755
External Links
Affiliation (based on the past Project Information)
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1995 – 1997: Kobe University School of Medicine The 1st Department of Internal Medicine Assos, 医学部, 講師
1994: 神戸大学, 医学部・付属病院, 講師
1994: 神戸大学, 医学部附属病院, 講師
1993 – 1994: Kobe University, Faculty of Medicine, Assistant Professor, 医学部・附属病院, 講師
1991 – 1992: Kobe University School of Medicine Hospital Assistant Professor, 医学部附属病院, 講師
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1991: 神戸大学, 医学部・附属病院, 講師
1991: 神戸大学, 医学部附属病院, 助手
1986 – 1990: Kobe University, Faculty of Medicine, Research Associate, 医学部, 助手
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Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine
Except Principal Investigator
Circulatory organs internal medicine
/
Pathological medical chemistry
/
物質生物化学
/
代謝生物化学
Keywords
Principal Investigator
血管平滑筋細胞 / 血管作動物質 / GTP結合蛋白質 / 血管平滑筋 / MAPキナーゼ / 一酸化窒素 / イノシト-ルリン脂質 / Cキナ-ゼ / 細胞増殖因子 / 発癌遺伝子
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More
/ ras癌遺伝子 / チロシンリン酸化反応 / プロテインキナ-ゼ / アンギオテンシンII / エンドセリン / MAPキナ-ゼ / ras / rho / 一酸化窒素合成酵素 / サイトカイン / アルギニン / アンジオテンシンll / シグナル伝達 / 低分子量G蛋白 / 接着斑 / パキシリン / アルギニントランスポーター / インターロイキン1 / 腫瘍壊死因子α / アンジオテンシンII / 増殖 / 形質変換 / アポトーシス
…
More
Except Principal Investigator
Cキナーゼ / 動脈硬化 / 細胞増殖因子 / GTP結合蛋白質 / 血管内皮細胞 / 内皮由来血管弛緩因子 / リゾホスファチジルコリン / Rho / ras p21 / ホスホリパーゼC / 低分子量GTP結合蛋白質 / Rab3A / Rabphilin-3A / Ras / NO合成酵素 / セロトニン / 血管平滑筋細胞 / 分子生物学 / fos遺伝子 / ras遺伝子 / プレニル化 / GDP / 内皮細胞 / 酸化低比重リポ蛋白 / 血管平滑筋 / endothelium-derived relaxing factor / lysophosphatidylcholine / REKS / Smg GDS / プロテインキナーゼ / small GTP-binding protein / 低比重リポ蛋白質 / プロテインキナーゼC / Lysophosphatidylcholine / Atherosclerosis / Protein kinase C / B-Raf / The ERM family / CD44 / 細胞膜受容体 / サイクリックAMP / PDGF / イノシトールリン脂質代謝 / Serotonin / cーfos / cーrafー1蛋白質 / Aキナーゼ / GAP / コレステロ-ル代謝 / ホスファチジルイノシト-ル(PI)回転 / マクロファ-ジ / 細胞内情報伝達機構 / イノシト-ル3リン酸(IP_3) / Cキナ-ゼ / リポ蛋白(a) / 細胞増殖 / エンドセリン / エンドセリン変換酵素 / 培養内皮細胞 / 心血管疾患 / Ca^<2+> / cyclic AMP / 癌遺伝子 / rasp21 / GTP交換反応調節蛋白質 / GTPase活性化蛋白質 / 腫瘍マ-カ- / <ras>___ー p21 / smgp25 / smgp21 / GDI / small GTP-binding proteins / prenylation / GTP exchange protein / GTPase activating protein / Tumor markers / イノシト-ル燐脂質代謝回転 / 細胞内カルシウム / 情報伝達機構 / 高比重リポ蛋白 / 酸化低比重リポ蛋白質 / endothelial cell / phosphatidyl inositol tunover / cytosolic calcium / oxidized LDL / HDL / signal transduction system / 活性制御蛋白質 / 標的蛋白質 / シナプス小胞 / 翻訳後修飾 / rho p21 / rho GDI / rac p21 / smg GDS / C末端側ペプチド / ファルネシル基転移酵素 / ゲラニルゲラニル基転移酵素 / Rho GDI / Rab / rabphilin-3A / 高比重リポ蛋白質 / 細胞内Ca^<2+>濃度 / vascular endothelial cells / low density lipoprotein / high density lipoprotein / nitric synthase / protein kinase C / intracellular calcium concentration / 一酸化窒素合成酵素 / 低比重リボ蛋白質 / 高比重リボ蛋白質 / リゾホスファチジツコリン / 細胞内Ca^2濃度 / Nitric oxide synthase / Oxidized low density lipoprotein / Vascular endothelial cells / 低分子量G蛋白質 / Rap1 / SmgGDS / SMAP / 14-3-3蛋白質 / ERM-CD44系 / 冠動脈萎縮 / 細胞内カルシウム濃度 / 急性心筋梗塞 / 冠動脈攣縮 / 遺伝子多型性 / serotonin / coronary spasm / atherosclerosis / vascular smooth muscle / molecular biology / intracellular calcium / acute myocardial infarction / polymorphism / トランスジェニックマウス / 遺伝子工学 / nitric oxyde synthase / endthelial cell / transgenic mice / genetic engineering / 核遺伝子 / 細胞内伝達系 / カルシウムイオン / Cell Surface Receptors / Nuclear Genes / Intracellular Messengers / Cyclic AMP / Calcium Ion / Protein Kinases / 冠萎縮 / コレステロール代謝 / アポ蛋白 / アスパラギン結合糖鎖 / 動脈硬化症 / カルシウム / cholesterol metabolism apolipoprotein / sugar chain / イノシトールリン脂質 / 受容体 / ジグリセリド / イノシトール三リン酸 / Phosphoinositide / Cell Surface Receptor / Phospholipase C / GTP-binding Protein / Protein Kinase C / 心筋細胞 / イノシト-ルリン脂質代謝 / プロティンキナ-ゼC / フェニレフリン / ATP / 心肥大 / プリン受容体 / 培養心筋細胞 / 百日咳毒素 / 自動拍動 / プロテインキナ-ゼC / adenosine trisphosphate(ATP) / P_2受容体 / 5HT_2受容体 / Purinergic receptor / Cultured myocyte / Pertussis toxin / Spontaneous beating / Phosphatidyl inositides / Cardiac hypertrophy / ヒスタミン / 心房性利尿ペプチド / リゾホスホリパ-ゼ / コレステロ-ル / サイクリックGMP / ノルエピネフリン / 冠動脈スパスム / Histamine / Vascular smooth muscle cell / Vascular endothelium / Low density lipoprotein / Endothelium-derived relaxing factor / Atrial natriuretic peptide
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Research Projects
(
28
results)
Co-Researchers
(
25
People)
Project Start Year (Newest)
Project Start Year (Oldest)
血管平滑筋細胞の形質変換、増殖とアポトーシスのシグナル伝達機構の解析
Principal Investigator
Principal Investigator
川原 康洋
Project Period (FY)
1997
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kobe University
ヒト細胞膜アルギニントランスポーターのクローン化とNO合成における役割
Principal Investigator
Principal Investigator
川原 康洋
Project Period (FY)
1996
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
The role of endothelial nitric oxide synthase in cardiovascular regulation. -approach using genetic engineering.
Principal Investigator
YOKOYAMA Mitsuhiro
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
エンドセリン変換酵素の調節機構ならびに病態モデルでのその発現の変化
Principal Investigator
川嶋 成乃亮
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
血管収縮物質のシグナル伝達と血管平滑筋細胞の遊走、増殖の制御機構
Principal Investigator
Principal Investigator
川原 康洋
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
Serotonin receptors and ischemic heart disease
Principal Investigator
YOKOYAMA Mitsuhiro
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
血管平滑筋細胞における誘導型NO合成酵素の発現制御機構とその病態
Principal Investigator
Principal Investigator
川原 康洋
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
動脈硬化発症進展におけるリポ蛋白(a)の役割
Principal Investigator
石川 雄一
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
An approach to understand the pathophysiological role of endothelial constitutive nitric oxide synthase
Principal Investigator
YOKOYAMA Mitsuhiro
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University School of Medicine
cDNAs and antibodies for small GTP-binding proteins
Principal Investigator
TAKAI Yoshimi
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
Osaka University
血管平滑筋細胞における血管作動物質のシグナル伝達と低分子量GTP結合蛋白質
Principal Investigator
Principal Investigator
川原 康洋
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
An approach to understand the interaction of lipoproteins and vascular endothelial cells
Principal Investigator
YOKOYAMA Mitsuhiro
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
血管作動物質と細胞増殖因子による血管平滑筋細胞の肥大,増殖機構とその病態
Principal Investigator
Principal Investigator
川原 康洋
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
cDNAs and antibodies for small GTP-binding proteins
Principal Investigator
TAKAI Yoshimi
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
代謝生物化学
Research Institution
Kobe University
血管平滑筋におけるrasP21類似低分子量GTP結合蛋白質の役割とその病態
Principal Investigator
Principal Investigator
川原 康洋
Project Period (FY)
1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
An approach to understand the mechanism and pathogenesis of production and release of endothelium-derived relaxing factor by molecular and cellular biology technique.
Principal Investigator
YOKOYAMA Mitsuhiro
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
細胞増殖シグナル伝達の機構と癌遺伝子産物の作用
Principal Investigator
TAKAI Yoshimi
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Kobe University
ヒト単球由来マクロファ-ジの脂質とりこみにおける分子生物学的機構の解析
Principal Investigator
ISHIKAWA Yuichi
Project Period (FY)
1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
血管平滑筋細胞の増殖機構における血管作動物質と細胞増殖因子の相乗作用とCキナ-ゼ
Principal Investigator
Principal Investigator
川原 康洋
Project Period (FY)
1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
cDNAs and Antibodies for Small GTP-binding Proteins
Principal Investigator
TAKAI Yoshimi
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for Developmental Scientific Research (B).
Research Field
Pathological medical chemistry
Research Institution
Kobe University
細胞の癌化におけるCキナーゼと癌遺伝子の相互作用
Principal Investigator
高井 義美
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Kobe University
細胞増殖因子による細胞周期の制御機構におけるCキナーゼの役割
Principal Investigator
高井 義美
Project Period (FY)
1988
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kobe University
Regulatory mechanisms of receptor-coupled signal transduction and its pathophysiologic state
Principal Investigator
FUKUZAKI Hisashi
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University School of Medicine
An approach to understand the pathogenesis of coronary artery spasm by molecular and cellular biology techniques
Principal Investigator
YOKOYAMA Mitsuhiro
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University School of Medicine
細胞の癌化におけるCキナーゼと癌遺伝子の相互作用
Principal Investigator
高井 義美
Project Period (FY)
1987
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Kobe University
Phosphoinositide metabolism in transmembrane signalling
Principal Investigator
TAKAI Yoshimi
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
物質生物化学
Research Institution
Kobe University
The mechanisms of the initiation and development of atherosclerosis
Principal Investigator
FUKUZAKI Hisashi
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Circulatory organs internal medicine
Research Institution
Kobe University
Mechanisms of signaling from cell surface receptors to nuclear genes.
Principal Investigator
TAKAI Yoshimi
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
物質生物化学
Research Institution
Kobe University
# of Projects (Dsc)
# of Projects (Asc)
1.
ISHIKAWA Yuichi
(90159707)
# of Collaborated Projects:
12 results
# of Collaborated Products:
0 results
2.
KAIBUCHI Kozo
(00169377)
# of Collaborated Projects:
11 results
# of Collaborated Products:
0 results
3.
YOKOYAMA Mitsuhiro
(40135794)
# of Collaborated Projects:
10 results
# of Collaborated Products:
0 results
4.
KIKUCHI Akira
(10204827)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
5.
TAKAI Yoshimi
(60093514)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
6.
KAWASHIMA Yasuhiro
(10177678)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
7.
TANIGUCHI Takahiro
(20263379)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
8.
AKITA Hozuka
(60175792)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
9.
KAWATA Masahito
(20224785)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
10.
SASAKI Takuya
(40241278)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
11.
YAMASHITA Takayuki
(10166671)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
12.
SANO Kimihiko
(40205993)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
13.
SUEMATU Masakuni
(90240853)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
FUKUZAKI Hisashi
(90030824)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
15.
溝口 明
(90181916)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
山田 充彦
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
INOUE Nobutaka
(10304099)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
KAWATA Sumio
(90183285)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
TANAKA Kazuma
(60188290)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
KANO Yoshio
(70116200)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
WATANABE Yoshio
(00031401)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
白河 卓
(30171044)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
高野 新二
(30116222)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
FUJIOKA Yoshio
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
矢谷 暁人
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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