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Kohno Nobuoki  河野 修興

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… Alternative Names

KOHNO Nobuoki  河野 修興

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Researcher Number 80215194
Other IDs
External Links
Affiliation (Current) 2022: 広島都市学園大学, 学長, 教授(移行)
Affiliation (based on the past Project Information) *help 2016: 広島大学, 医歯薬保健学研究院(医), 教授
2012 – 2015: 広島大学, 大学院医歯薬保健学研究院, 教授
2013: 広島大学, 医歯薬保健学研究院(医), 教授
2011: 広島大学, 大学院医歯薬学総合研究科, 教授
2010: 広島大学, 大学院・医歯薬総合研究科, 教授 … More
2009: 広島大学, 医歯薬学総合研究科, 教授
2002 – 2009: 広島大学, 大学院・医歯薬学総合研究科, 教授
2007: 広島大学, 医歯薬学総合研究科, 教授
2006: Hiroshima University, Graduate School of Biomedical Sciences, Professor, 大学院医歯薬学総合研究科, 教授
2000 – 2001: HIROSHIMA UNIVERSITY, FACULTY OF MEDICINE, PROFESSOR, 医学部, 教授
1993 – 2000: Ehime University school of medicine, Lecturer, 医学部・附属病院, 講師
1994: Ehime Univ.Hospital, Lecturer, 医学部・付属病院, 講師
1994: 愛媛大学, 医学部附属病院, 講師
1992: 愛媛大学, 医学部附属病院, 講師
1990 – 1991: 愛媛大学, 医学部・附属病院, 講師 Less
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine / Respiratory organ internal medicine / 内科学一般
Except Principal Investigator
Respiratory organ internal medicine / Respiratory organ internal medicine
Keywords
Principal Investigator
KL-6 / MUC1 / 間質性肺炎 / 肺癌 / モノクローナル抗体 / バイオマーカー / 人種差 / マイクロアレイ / 分子標的治療薬 / monoclonal antibody … More / PEP-76 / 血清マーカー / 予後因子 / CAIMAN / ECLIA / lung cancer / tandem repeat / 血清マ-カ- / KLー6抗原 / PIIIP / TypeIV collagen7S / 呼吸器病学 / 薬剤性肺障害 / 医療・福祉 / ゲノム / 糖鎖 / SNP / 分化誘導 / 乳癌細胞 / 増殖抑制 / 細胞接着 / 分化 / インテグリン / エストロ-ゲン・リセプタ- / モノクロ-ナル抗体 / differentiation / breast cancer / growth inhibition / cell adhesion / KL-6亜分子 / HK-7抗体 / ムチン / クラスター9 / KL-6 sub-molecules / interstitial pneumoitis / EK-7 antibody / 非小細胞肺癌 / 抗MUC1自己抗体 / 自己抗体 / 抗MUC1抗体 / LUNG CANCER / NON-SMALL CELL LUNG CANCER / PROGNOSTIC FACTOR / ANTI-MUC1 NATURAL AUTOANYTIBODY / マウスモノクローナル抗体 / ヒトモノクローナル抗体 / キメラ抗体 / 抗体補充療法 / Muc1 / Lung Cancer / mouse monoclonal antibody / human monoclonal antibody / chimera antibody / antibody supplement therapy / MUC1ムチン / 電機化学発光免疫測定 / 電機化学発光免疫測定法 / MUCIムチン / ECL1A / 電気化学発光 / MUC1 mucin / serum marker / electrochemiluminescence immunoassay / interstitial pneumonitis / 特発性間質性肺炎 / MUC1多型 / 胎児肺 / 霊長類 / 突発性間質性肺炎 / 特発性間質性 / MUCl / 肺胞II型上皮 / Protease / サイトカイン / 線維芽細胞 / ヒト肺胞上皮細胞 / アポトーシス / idiopathic interstitial pneumonia / prognostic factor / MUC1 polymorphism / embryo lung / primates … More
Except Principal Investigator
肺線維症 / 気管支喘息 / サイトカイン / KL-6 / 肺癌 / 好酸球 / cytokine / bronchial asthma / イノシトールポリリン酸 / ホスファチジルイノシトール / 細胞増殖 / 細胞増殖抑制 / イノシトール / PInsP(3、4)_2 / PIP(3、4、5)_3 / MUC1ムチン / 急性呼吸窮迫症候群 / セレクチン / 汎発性血管内凝固症候群 / 成人呼吸促迫症候群 / 縦隔リンパ節転移 / 癌転移抑制遺伝子 / シメチジン / 慢性閉塞性肺疾患 / ムチン / バイオマーカー / 人種差 / 肺がん / マウスモデル / トロンボキサンA2 / 気管支肺胞洗浄 / インターロイキン5 / T細胞クローン / ヘルパーT細胞 / 受身移入実験 / Eosinophil / Murine model / Bronchial asthma / Thromboxane A_2 / Bronchoalveolar lavage / Cytokine / Interleukin-5 / インターロイキン / SOCS / IL-12 / IL-10 / 転写因子 / 悪性中皮腫 / eosinophil / interleukin / 線維芽細胞 / T細胞 / インターフェロン / リモデリング / fibroblast / T cells / interferon / pulmonary fibrosis / remodeling / 線溶系 / 遺伝子治療 / RNA干渉 / Pulmonary fibrosis / Fibrinolytic system / Gene therapy / RNA interference Less
  • Research Projects

    (18 results)
  • Research Products

    (164 results)
  • Co-Researchers

    (33 People)
  •  国際共同研究による間質性肺炎の新規バイオマーカーの開発と創薬の試みPrincipal Investigator

    • Principal Investigator
      河野 修興
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hiroshima University
  •  Anti KL-6 antibody enhances the effects of molecular targeted drugPrincipal Investigator

    • Principal Investigator
      KOHNO Nobuoki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hiroshima University
  •  The elucidation of an ethnic difference of lung cancer and the development of a new therapy

    • Principal Investigator
      ISHIKAWA Nobuhisa
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hiroshima University
  •  Comparative studies of a clinical features and genomic analysis in patients with interstitial lung disease and drug induced lung injuryPrincipal Investigator

    • Principal Investigator
      KOHNO Nobuoki
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hiroshima University
  •  Clinicopathological role of kl-6/muc1 with selectin ligand

    • Principal Investigator
      YOKOYAMA Akihito
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kochi University
  •  Experimental investigation for the development of therapeutic approaches to inhibit metastasis to mediastinal lymph node in lung cancer

    • Principal Investigator
      KONDOH Tomohiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hiroshima University
  •  Development of gene therapy utilizing fibrinolytic system for pulmonary fibrosis

    • Principal Investigator
      HATTORI Noboru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Regulatory mechanisms for lung and airway fibrosis

    • Principal Investigator
      YOKOYAMA Akihito
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hiroshima University
  •  The Study on KL-6 as Morbidity Ornamentation Factor and Prognosis Factor of Idiopathic Interstitial Pneumonia.Principal Investigator

    • Principal Investigator
      KOHNO Nobuoki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  The Establishment of KL-6 Associated New Serum Markers Using High Sensitive Electrochemiluminescence Immunoassay.Principal Investigator

    • Principal Investigator
      KOHNO Nobuoki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Approaches to the pathogenesis of bronchial asthma

    • Principal Investigator
      YOKOYAMA Akihito
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      HIROSHIMA UNIVERSIlY
      Ehime University
  •  DEVELOPMENT OF A LUNG CANCER TREATMENT USING ANTI-KL-6/MUC1 MULTI-MONOCLONAL ANTIBODIESPrincipal Investigator

    • Principal Investigator
      KOHNO Nobuoki
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      HIROSHIMA UNIVERSITY
      Ehime University
  •  Clinical Significance of Anti-MUC1 Natural Autoantibody in Sera from Patients with Lung CancerPrincipal Investigator

    • Principal Investigator
      KOHNO Nobuoki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      EHIME UNIVERSITY
  •  イノシトール類による細胞の増殖ないし抑制作用の研究

    • Principal Investigator
      尾崎 庄一郎
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Ehime University
  •  Screening of new KL-6-associated mucins useful in clinical diagnosis of interstitial pneumonitisPrincipal Investigator

    • Principal Investigator
      KOHNO Nobuoki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      EHIME UNIVERSITY
  •  Murine models of pulmonary diseases induced by adoptive transfer of T cell clones.

    • Principal Investigator
      YOKOYAMA Akihito
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Ehime University
  •  Differentiation Induction of a Cell Line with a Monoclonal AntibodyPrincipal Investigator

    • Principal Investigator
      KOHNO Nobuoki
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Ehime University School of Medicine
  •  間質性肺炎における血清中ムチン型糖蛋白(KLー6抗原)の臨床的有用性に関する研究Principal Investigator

    • Principal Investigator
      河野 修興
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Ehime University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] がんの浸潤・転移2011

    • Author(s)
      石川暢久,河野修興
    • Total Pages
      241
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Book] 間質性肺疾患診療マニュアル2010

    • Author(s)
      石川暢久, 河野修興
    • Total Pages
      329
    • Publisher
      KL-6
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Book] KL-6.間質性肺疾患診療マニュアル2010

    • Author(s)
      石川暢久, 河野修興
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Book] がん化学療法・分子標的治療 update2009

    • Author(s)
      石川暢久, 河野修興
    • Total Pages
      736
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Book] 肺毒性・心毒性.癌化学療法update 2010-20112009

    • Author(s)
      石川暢久, 河野修興
    • Publisher
      中外医薬社
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Book] んがで読み解く呼吸器症例1002009

    • Author(s)
      河野修興監修,横山彰仁,森山美智子,服部登(編集)
    • Total Pages
      284
    • Publisher
      メディカルビュー社
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Book] がん化学療法・分子標的治療 update2009

    • Author(s)
      石川暢久, 河野修興
    • Total Pages
      736
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Book] BAL法の臨床応用. 気管支肺胞洗浄(BAL)の手引き2008

    • Author(s)
      服部登, 河野修興監修
    • Publisher
      京誠堂出版社
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Book] 内科学第9版2007

    • Author(s)
      河野 修興
    • Publisher
      朝倉書店,東京
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Book] 呼吸器疾患のバイオマーカー. 内科学第9版(杉本恒明・矢崎義雄総編集)2007

    • Author(s)
      河野修興
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Book] 呼吸器疾患最新の治療2004-20062005

    • Author(s)
      河野修興
    • Total Pages
      458
    • Publisher
      急性間質性肺炎
    • Data Source
      KAKENHI-PROJECT-14370197
  • [Journal Article] Comparative Study of Circulating MMP-7, CCL18, KL-6, SP-A, and SP-D as Disease Markers of Idiopathic Pulmonary Fibrosis2016

    • Author(s)
      Kosuke Hamai, Hiroshi Iwamoto*, Nobuhisa Ishikawa, Yasushi Horimasu, Takeshi Masuda, Shintaro Miyamoto, Taku Nakashima, Shinichiro Ohshimo, Kaznounori Fujitaka, Hironobu Hamada , Noboru Hattori, Nobuoki Kohno
    • Journal Title

      Disease markers

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Journal Article] Long-term pulmonary complications of chemical weapons exposure in former poison gas factory workers.2016

    • Author(s)
      Nishimura Y, Iwamoto H, Ishikawa N, Hattori N, Horimasu Y, Ohshimo S, Kohno N.
    • Journal Title

      Inhal Toxicol

      Volume: 28 Pages: 343-348

    • DOI

      10.3109/08958378.2016.1173133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-16K09541
  • [Journal Article] MUC5B promoter polymorphism in Japanese patients with idiopathic pulmonary fibrosis.2015

    • Author(s)
      Horimasu Y, Ohshimo S, Bonella F, Tanaka S, Ishikawa N, Hattori N, Kohno N, Guzman J, Costabel U.
    • Journal Title

      Respirology

      Volume: 20 Pages: 439-44

    • DOI

      10.1111/resp.12466

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-25860646
  • [Journal Article] MT95-4, a fully humanized antibody raised against aminopeptidase N, reduces tumor progression in a mouse model2015

    • Author(s)
      Akita S, Hattori N, Masuda T, Horimasu Y, Nakashima T, Iwamoto H, Fujitaka K, Miyake M, Kohno N
    • Journal Title

      Cancer Sci.

      Volume: 106 Pages: 921-8

    • DOI

      10.1111/cas.12692

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K21190, KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-15H04831, KAKENHI-PROJECT-25860645
  • [Journal Article] Effect of increasing respiratory rate on airway resistance and reactance in COPD patients.2015

    • Author(s)
      Nakagawa M, Hattori N, Haruta Y, Sugiyama A, Iwamoto H, Ishikawa N, Fujitaka K, Murai H, Tanaka J, Kohno N.
    • Journal Title

      Respirology

      Volume: 20 Pages: 87-94

    • DOI

      10.1111/resp.12387

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Journal Article] A pilot study: a combined therapy using polymyxin-B hemoperfusion and extracorporeal membrane oxygenation for acute exacerbation of interstitial pneumonia.2015

    • Author(s)
      Itai J, Ohshimo S, Kida Y, Ota K, Iwasaki Y, Hirohashi N, Bonella F, Guzman J, Costabel U, Kohno N, Tanigawa K.
    • Journal Title

      Sarcoidosis Vasc Diffuse Lung Dis

      Volume: 31 Pages: 343-349

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Journal Article] Histological quantification of gene silencing by intratracheal administration of dry powdered small-interfering RNA/chitosan complexes in the murine lung.2015

    • Author(s)
      Ihara D, Hattori N, Horimasu Y, Masuda T, Nakashima T, Senoo T, Iwamoto H, Fujitaka K, Okamoto H, Kohno N
    • Journal Title

      Pharm Res

      Volume: 32 Pages: 3877-3785

    • DOI

      10.1007/s11095-015-1747-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K21190, KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-15H04831
  • [Journal Article] Airway inflammation in Japanese COPD patients compared with smoking and non-smoking controls.2015

    • Author(s)
      Nobuhisa Ishikawa,1 Noboru Hattori,2 Nobuoki Kohno, Akihiro Kobayashi, Tomoyuki Hayamizu, Malcolm Johnson
    • Journal Title

      Int J Chron Obstruct Pulmon Dis

      Volume: 10 Pages: 185-192

    • DOI

      10.2147/copd.s74557

    • NAID

      120006799350

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Journal Article] Differences in serum SP-D levels between German and Japanese subjects are associated with SFTPD gene polymorphisms2014

    • Author(s)
      Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Bonella F, Ohshimo S, Guzman J, Costabel U, Kohno N
    • Journal Title

      BMC Med Genet

      Volume: 15 Pages: 4-4

    • DOI

      10.1186/1471-2350-15-4

    • NAID

      120006799353

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-25860646
  • [Journal Article] Baseline KL-6 predicts increased risk for acute exacerbation of idiopathic pulmonary fibrosis.2014

    • Author(s)
      Ohshimo S, Ishikawa N, Horimasu Y, Hattori N, Hirohashi N, Tanigawa K, Kohno N, Bonella F, Guzman J, Costabel U
    • Journal Title

      Respir Med

      Volume: 108 Pages: 1031-1039

    • DOI

      10.1016/j.rmed.2014.04.009

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-25860646
  • [Journal Article] RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer2013

    • Author(s)
      Oshita H, Nishino R, Takano A, Fujitomo T, Aragaki M, Kato T, Akiyama H, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y.
    • Journal Title

      Mol Cancer Res

      Volume: 11 Pages: 937-951

    • DOI

      10.1158/1541-7786.mcr-12-0685-t

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650624, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-24390145, KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-221S0001
  • [Journal Article] A nationwide epidemiological survey of chronic hypersensitivity pneumonitis in Japan.2013

    • Author(s)
      Okamoto T, Miyazaki Y, Ogura T, Chida K, Kohno N, Kohno S, Taniguchi H, Akagawa S, Mochizuki Y, Yamauchi K, Takahashi H, Johkoh T, Homma S, Kishi K, Ikushima S, Konno S, Mishima M, Ohta K, Nishioka Y, Yoshimura N, Munakata M, Watanabe K, Miyashita Y, Inase N.
    • Journal Title

      Respir Investig

      Volume: 51 Pages: 191-199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Journal Article] SK-216, an inhibitor of plasminogen activator inhibitor-1, limits tumor progression and angiogenesis.2013

    • Author(s)
      Masuda T, Hattori N, Senoo T, Akita S, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Kohno N.
    • Journal Title

      Mol Cancer Ther

      Volume: 12 Pages: 2378-2388

    • DOI

      10.1158/1535-7163.mct-13-0041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-25253057
  • [Journal Article] Characteristics of inspiratory and expiratory reactance in interstitial lung disease.2013

    • Author(s)
      Sugiyama A, Hattori N, Haruta Y, Nakamura I, Nakagawa M, Miyamoto S, Onari Y, Iwamoto H, Ishikawa N, Fujitaka K, Murai H, Kohno N.
    • Journal Title

      Respir Med

      Volume: 107 Pages: 875-82

    • DOI

      10.1016/j.rmed.2013.03.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-25253057
  • [Journal Article] Cross-sectional and prospective study of the association between lung function and prediabetes.2013

    • Author(s)
      Yamane T, Yokoyama A, Kitahara Y*, Miyamoto S, Haruta Y, Hattori N, Yamane K, Hara H, Kohno N
    • Journal Title

      BMJ Open

      Volume: 3 Pages: 3-3

    • DOI

      10.1136/bmjopen-2012-002179

    • NAID

      120006799354

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-24659405, KAKENHI-PROJECT-25253057
  • [Journal Article] A nationwide epidemiological survey of chronic hypersensitivity pneumonitis in Japan.2013

    • Author(s)
      Okamoto T, Miyazaki Y, Ogura T, Chida K, Kohno N, Kohno S, Taniguchi H, Akagawa S, Mochizuki Y, Yamauchi K, Takahashi H, Johkoh T, Homma S, Kishi K, Ikushima S, Konno S, Mishima M, Ohta K, Nishioka Y, Yoshimura N, Munakata M, Watanabe K, Miyashita Y, Inase N.
    • Journal Title

      Respir Investig

      Volume: 51 Pages: 191-199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Journal Article] SK-216, an inhibitor of plasminogen activator inhibitor-1, limits tumor progression and angiogenesis2013

    • Author(s)
      Masuda T, Hattori N, Senoo T, Akita S, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Kohno N
    • Journal Title

      Mol Cancer Ther

      Volume: 12 Pages: 2378-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Journal Article] Different MUC1 gene polymorphisms in German and Japanese ethnicities affect serum KL-6 levels.2012

    • Author(s)
      Horimasu Y, Hattori N, Ishikawa N, K awase S, Tanaka S, Yoshioka K, Yokoy ama A, Kohno N, Bonella F, Guzman J, Ohshimo S, Costabel U
    • Journal Title

      Respir Med

      Volume: 106 Pages: 1756-1764

    • DOI

      10.1016/j.rmed.2012.09.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-24659405
  • [Journal Article] Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected nonsmall cell lung cancer2012

    • Author(s)
      Tanaka S, et al.
    • Journal Title

      Int J Cancer

      Volume: 130 Pages: 377-387

    • DOI

      10.1002/ijc.26007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390165, KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433
  • [Journal Article] Interferon (alpha, beta and omega) receptor 2 is a prognostic biomarker for lung cancer2012

    • Author(s)
      Tanaka S, Hattori N, Ishikawa N, Horimasu Y, Deguchi N, Takano A, Tomoda Y, Yoshioka K, Fujitaka K, Arihiro K, Okada M, Yokoyama A, Kohno N
    • Journal Title

      Pathobiology

      Volume: 79 Pages: 24-33

    • DOI

      10.1159/000331230

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Journal Article] Utility of KL-6/MUC1 in the c linical management of interstitial lu ng diseases2012

    • Author(s)
      Ishikawa N, Hattori N, Yokoyama A, Kohno N
    • Journal Title

      Respir Investig

      Volume: 50 Pages: 3-13

    • DOI

      10.1016/j.resinv.2012.02.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-24659405
  • [Journal Article] KL-6 concentration in pulmonary epithelial lining fluid is a useful prognostic indicator in patients with acute respiratory distress syndrome.2011

    • Author(s)
      Kondo T, Hattori N, Ishikawa N, Murai H, Haruta Y, Hirohashi N, Tanigawa K, Kohno N.
    • Journal Title

      Respir Res

      Volume: 12 Pages: 32-32

    • DOI

      10.1186/1465-9921-12-32

    • NAID

      120003692470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433
  • [Journal Article] Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in acute respiratory distress syndrome.2011

    • Author(s)
      Nakashima T, Yokoyama A, Inata J, Ishikawa N, Haruta Y, Hattori N, Kohno N.
    • Journal Title

      Chest 139(2)

      Pages: 296-304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Change in serum KL-6 level from baseline is useful for predicting life-threatening EGFR-TKIs induced interstitial lung disease.2011

    • Author(s)
      Kawase S, et al
    • Journal Title

      Respir Res

      Volume: 12 Pages: 97-97

    • DOI

      10.1186/1465-9921-12-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433
  • [Journal Article] Levels of surfactant proteins A and D and KL-6 are elevated in the induced sputum of chronic obstructive pulmonary disease patients : a sequential sputum analysis2011

    • Author(s)
      Ishikawa N, et al
    • Journal Title

      Respira tion

      Volume: 82 Pages: 10-18

    • DOI

      10.1159/000324539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390165, KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-24659405
  • [Journal Article] KL-6 Concentration in Pulmonary Epithelial Lining Fluid and Is a Useful Prognostic Indicator in Patients with Acute Respiratory Distress Syndrome.2011

    • Author(s)
      Kondo T, Hattori N, Ishikawa N, Murai H, Haruta Y, Hirohashi N, Tanigawa K, Kohno N.
    • Journal Title

      Respiratory Research 12(1)

      Pages: 32-32

    • NAID

      120003692470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Krebs von den Lungen-6 (KL-6) is a Prognostic Biomarker for Non-SmallCell Lung Cancer2011

    • Author(s)
      Tanaka S, Hattori N, Ishikawa N, Takano A, Nishino R, Shoda H, Yoshioka K, Akita S, Miyata Y, Okada M, Arihiro K, Inai K, Yokoyama A, Kohno N.
    • Journal Title

      Int J Cancer

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Surfactant protein A and KL-6 are elevated in the induced sputum of COPD ; a sequential sputum analysis2011

    • Author(s)
      Ishikawa N, Hattori N, Tanaka S, Horimasu Y, Haruta Y, Yokoyama A, Kohno N, Kinnula VL.
    • Journal Title

      Respiration

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Erlotinib efficacy and cerebrospinal fluid concentration in lung adenocarcinoma patients developing leptomeningeal metastases during gefitinib therapy2011

    • Author(s)
      Masuda T, Hattori N, Hamada A, Iwamoto H, Ohshimo S, Kanehara M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Kohno N
    • Journal Title

      Cancer Chemoth Pharm

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Comparison of serum KL-6 versus bronchoalveolar lavage neutrophilia for the diagnosis of bronchiolitis obliterans in lung transplantation.2011

    • Author(s)
      Ohshimo S, Bonella F, Sommerwerck U, Teschler H, Kamler M, Jakob HG, Kohno N, Guzman J, Costabel U.
    • Journal Title

      J Heart Lung Transplant

      Volume: 30 Pages: 1374-1380

    • DOI

      10.1016/j.healun.2011.07.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Journal Article] KL-6 Concentration in Pulmonary Epithelial Lining Fluid and Is a Useful Prognostic Indicator in Patients with Acute Respiratory Distress Syndrome.2011

    • Author(s)
      Kondo T, Hattori N, Ishikawa N, Murai H, Haruta Y, Hirohashi N, Tanigawa K, Kohno N.
    • Journal Title

      Respiratory Research

      Volume: 12(電子媒体)

    • NAID

      120003692470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma.2011

    • Author(s)
      Ishikawa N, Mazur W, Toljamo T, Vuopala K, Rönty M, Horimasu Y, Kohno N, Kinnula VL.
    • Journal Title

      BMC Pulm Med

      Volume: 11 Pages: 22-22

    • DOI

      10.1186/1471-2466-11-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433
  • [Journal Article] Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma.2011

    • Author(s)
      Ishikawa N, Mazur W, Toljamo T, Vuopala K, Ronty M, Horimasu Y, Kohno N, Kinnula VL.
    • Journal Title

      BMC Pulm Med 11(1)

      Pages: 22-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in acute respiratory distress syndrome2011

    • Author(s)
      Nakashima T, Yokoyama A, Inata J, Ishikawa N, Haruta Y, Hattori N, Kohno N
    • Journal Title

      Chest

      Volume: 139 Pages: 296-304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in acute respiratory distress syndrome.2011

    • Author(s)
      Nakashima T, et al
    • Journal Title

      Chest

      Volume: 139 Pages: 296-304

    • DOI

      10.1378/chest.09-3082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390165, KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433
  • [Journal Article] Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis.2010

    • Author(s)
      Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Yokoyama A, Kohno N
    • Journal Title

      Thorax 2010 65

      Pages: 334-340

    • NAID

      120002398984

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] 間質性肺炎と肺癌2010

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      癌と化学療法 37

      Pages: 6-9

    • NAID

      10025609136

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] 間質性肺炎と肺癌2010

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      癌と化学療法

      Volume: 37 Pages: 6-9

    • NAID

      10025609136

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Non-coding regionにおける遺伝子制御の最近の知見VNTR(variable number of tandem repeats)遺伝子多型による癌の進行度診断2010

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      Surgery Frontier

      Volume: 17 Pages: 56-58

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Suppression of plasminogen activator inhibitor-1 by RNA interference at tenuates pulmonary fibrosis2010

    • Author(s)
      Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Yokoyama Y, Kohno N
    • Journal Title

      Thorax

      Volume: 65 Pages: 334-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis.2010

    • Author(s)
      Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Yokoyama Y, Kohno N.
    • Journal Title

      Thorax 65

      Pages: 334-340

    • NAID

      120002398984

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Non-coding regionにおける遺伝子制御の最近の知見VNTR(variable number of tandem repeats)遺伝子多型による癌の進行度診断2010

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      Surgery Frontier 17

      Pages: 56-58

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis.2010

    • Author(s)
      Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, Fuji taka K, Haruta. Y, Murai H, Yokoyama A, Kohno N
    • Journal Title

      Thorax 65

      Pages: 334-40

    • NAID

      120002398984

    • Data Source
      KAKENHI-PROJECT-19590898
  • [Journal Article] IL-12p40 is essential for the down-regulation of airway hyperresponsiveness in a mouse model of bronchial asthma with prolonged antigen exposure2009

    • Author(s)
      Onari Y, Yokoyama A, Haruta Y, Nakashima T, Iwamoto H, Hattori N, Kohno N
    • Journal Title

      Clin Exp Allergy 39

      Pages: 290-298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] Lymphocyte transformation test is not helpful for the diagnosis of methotrexate-induced pneumonitis in patients with rheumatoid arthritis.2009

    • Author(s)
      Hirata S, Hattori N, Kumagai K, Haruta Y, Yokoyama A, Kohno N
    • Journal Title

      Clin Chim Acta 2009 407

      Pages: 25-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] Significance of bronchoalveolar lavage for the diagnosis of idiopathic pulmonary fibrosis.2009

    • Author(s)
      Ohshimo S, Bonella F, Cui A, Beume M, Kohno N, Guzman J, Costabel U
    • Journal Title

      Am J Respir Crit Care Med 2009 179

      Pages: 1043-1047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] Airflow limitation in smokers is associated with subclinical atherosclerosis2009

    • Author(s)
      Iwamoto H, Yokoyama A, Kitahara Y, Ishikawa N, Haruta Y, Yamane K, Hattori N, Hara H, Kohno N
    • Journal Title

      Am J Respir Crit Care Med 179

      Pages: 35-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] Airflow limitation in smokers is associated with subclinical atherosclerosis.2009

    • Author(s)
      Iwamoto H, Yokoyama A, Kitahara Y, Ishikawa N, Haruta Y, Yamane K, Hattori N, Hara H, Kohno N
    • Journal Title

      Am J Respir Crit Care Med 2009 179

      Pages: 35-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] シアル化糖鎖抗原KL-62009

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      広範囲血液・尿化学検査免疫学的検査(第7版)

      Pages: 358-360

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: role of IL-6.2009

    • Author(s)
      animoto T, Hattori N, Senoo T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Igarashi K, Kohno N
    • Journal Title

      Free Radic Biol Med 2009 46

      Pages: 1119-1126

    • NAID

      120001700407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] シアル化糖鎖抗原KL-62009

    • Author(s)
      石川暢久, 河野修興.
    • Journal Title

      広範囲血液・尿化学検査, 免疫学的検査 (第7版) 1-その数値をどう読むか-

      Pages: 358-360

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Serum KL-6 as a novel disease marker in adolescent and adult cystic fibrosis.2009

    • Author(s)
      Ohshimo S, Bonella F, Grammann N, Starke K, Cui A, Bauer PC, Teschler H, Kohno N, Guzman J, Costabel U
    • Journal Title

      Sarcoidosis Vasc Diffuse Lung Dis 2009 26

      Pages: 47-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] 間質性肺炎のマーカーKL-6,SP-A,SP-D2009

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      診断と治療 97

      Pages: 1773-1777

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.2009

    • Author(s)
      Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N
    • Journal Title

      J Pharmacol Exp Ther 2009 328

      Pages: 55-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] Perceived stress, severity of asthma and quality of life in young adults with asthma2009

    • Author(s)
      Kimura T, Yokoyama A, Kohno N, Nakamura H, Eboshida A.
    • Journal Title

      Allergol Int 58

      Pages: 71-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] 間質性肺炎のマーカー : KL-6, SP-A, SP-D2009

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      診断と治療 97

      Pages: 1773-1777

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice2009

    • Author(s)
      Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N
    • Journal Title

      J Pharmacol Exp Ther 328

      Pages: 55-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] IL-12p40 is essential for the down-regulation of airway hyperresponsiveness in a mouse model of bronchial asthma with prolonged antigen exposure.2009

    • Author(s)
      Onari Y, Yokoyama A, Haruta Y, Nakashima T, Iwamoto H, Hattori N, Kohno N
    • Journal Title

      Clin Exp Allergy 2009 39

      Pages: 290-298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] 腫瘍マーカーは肺がん診療に,どのように使われますか?2008

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      ナーシングケアQ&A 19

      Pages: 72-73

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] 間質性肺炎のマーカーKL-62008

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      日本胸部臨床 67

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.2008

    • Author(s)
      Ishikawa N, Hattori N, Yokoyama A, Tanaka S, Nishino R, Yoshioka K, Ohshimo S, Fujitaka K, Ohnishi H, Hamada H, Arihiro K, Kohno N
    • Journal Title

      nt J Cancer 2008 122

      Pages: 2612-2620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] Suppressor of cytokine signaling 1 inhibits pulmonary inflammation and fibrosis2008

    • Author(s)
      Nakashima T, Yokoyama A, Onari Y, Shoda H, Haruta Y, Hattori N, Naka T, Kohno N
    • Journal Title

      J Allergy Clin Immunol 2008 121

      Pages: 1269-1276

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] 腫瘍マーカーのバイオマーカーとしての臨床的意義2008

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      医学のあゆみ「肺癌UPDATE」 224

      Pages: 1159-1163

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] 間質性肺炎のマーカー・KL-62008

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      呼吸器疾患の臨床検査up to date 67

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Suppressor of cytokine signaling 1 inhibits pulmonary inflammation and fibrosis2008

    • Author(s)
      Nakashima T, Yokoyama A, Onari Y, Shoda H, Haruta Y, Hattori N, Naka T, Kohno N
    • Journal Title

      J Allergy Clin Immunol 121

      Pages: 1269-1276

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.2008

    • Author(s)
      Ishikawa N, Hattori N, Yokoyama A, Tanaka S, Nishino R, Yoshioka K, Ohshimo S, Fujitaka K, Ohnishi H, Hamada H, Arihiro K, Kohno N.
    • Journal Title

      Int J Cancer 122

      Pages: 2612-2620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome.2008

    • Author(s)
      Nakashima T, Yokoyama A, Ohnishi H, Hamada H, Ishikawa N, Haruta Y, Hattori N, Tanigawa K, Kohno N
    • Journal Title

      J Intern Med 2008 263

      Pages: 432-439

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] 腫瘍マーカーのバイオマーカーとしての臨床的意義2008

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      医学のあゆみ 224

      Pages: 1159-1163

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome.2008

    • Author(s)
      Nakashima T, Yokoyama A, Ohnishi H, Hamada H, Ishikawa N, Haruta Y, Hattori N, Tanigawa K, Kohno N.
    • Journal Title

      J Intern Med 263

      Pages: 432-439

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors2008

    • Author(s)
      Ishikawa N, Hattori N, Yokoyama A, Tanaka S, Nishino R, Yoshioka K, Ohshimo S, Fujitaka K, Ohnishi H, Hamada H, Arihiro K, Kohno N
    • Journal Title

      Int J Cancer 122

      Pages: 2612-2620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome2008

    • Author(s)
      Nakashima T, Yokoyama A, Ohnishi H, Hamada H, Ishikawa N, Haruta Y, Hattori N, Tanigawa K, Kohno N
    • Journal Title

      J Intern Med 263

      Pages: 432-439

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] Anti-inflammatory effects and clinical efficacy of theophylline and tulobuterol in mild-to-moderate chronic obstructive pulmonary disease.2008

    • Author(s)
      Kanehara M, Yokoyama A, Tomoda Y, Shiota N, Iwamoto H, Ishikawa N, Taooka Y, Haruta Y, Hattori N, Kohno N
    • Journal Title

      Pulm Pharmacol Ther 2008 21

      Pages: 874-878

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] Anti-inflammatory effects and clinical efficacy of theophylline and tulobuterol in mild-to-moderate chronic obstructive pulmonary disease2008

    • Author(s)
      Kanehara M, Yokoyama A, Tomoda Y, Shiota N, Iwamoto H, Ishikawa N, Taooka Y, Haruta Y, Hattori N, Kohno N
    • Journal Title

      Pulm Pharmacol Ther 21

      Pages: 874-878

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] 薬剤性肺障害2008

    • Author(s)
      石川暢久, 河野修興
    • Journal Title

      リウマチ科 40

      Pages: 363-370

    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Differential expression of the glycosylated forms of MUC1 during lung development.2007

    • Author(s)
      Sakurai J, Hattori N, Nakajima M, Moriya T, Suzuki T, Yokoyama A, Kohno N
    • Journal Title

      Eur J Histochem 2007 51

      Pages: 95-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] Immunohistochemical and immunoelectron microscopic studies of the localization of KL-6 and epithelial membrane antigen (EMA) in presumably normal pulmonary tissue and in interstitial pneumonia2007

    • Author(s)
      Ohtsuki Y, Fujita J, Hachisuka Y, Uomoto M, Okada Y, Yoshinouchi T, Lee GH, Furihata M, Kohno N
    • Journal Title

      Med Mol Morphol 40

      Pages: 198-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] Circulating KL-6/MUC1 mucin carrying sialyl Lewisa oligcsaccharide is an independent prognostic factor in patients with lung adenocarcinoma2007

    • Author(s)
      Inata J, Hattori N, Yokoyama A, Ohshimo S, Doi M, Ishikawa N, Hamada H, Kohno N
    • Journal Title

      Int J Cancer 120

      Pages: 2643-2649

    • Data Source
      KAKENHI-PROJECT-19590898
  • [Journal Article] Immunohistochemical and immunoelectron microscopic studies of the localization of KL-6 and epithelial membrane antigen (EMA) in presumably normal pulmonary tissue and in interstitial pneumonia.2007

    • Author(s)
      Ohtsuki Y, Fujita J, Hachisuka Y, Uomoto M, Okada Y, Yoshinouchi T, Lee GH, Furihata M, Kohno N
    • Journal Title

      Med Mol Morphol 2007 40

      Pages: 198-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] Differential expression of the glycosylated forms of MUC1 during lung development2007

    • Author(s)
      Sakurai J, Hattori N, Nakajima M, Moriya T, Suzuki T, Yokoyama A, Kohno N
    • Journal Title

      Eur J Histochem 51

      Pages: 95-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] Overproduction of collagen and diminished SOCS1 expression are causally linked in fibroblasts from idiopathic pulmonary fibrosis2007

    • Author(s)
      Shoda H, Yokoyama A, Nishino R, Nakashima T, Ishikawa N, Haruta Y, Hattori N, Naka T, Kohno N.
    • Journal Title

      Biochem Biophys Res Commun 353

      Pages: 1004-1010

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590747
  • [Journal Article] Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas2007

    • Author(s)
      Ishikawa N, Takano A, Yasui W, Inai K, Nishimura H, Ito H, Miyagi Y, Nakayama H, Fujita M, Hosokawa M, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y
    • Journal Title

      Cancer Res 1567

      Pages: 11601-11611

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer2007

    • Author(s)
      Taniwaki M, Takano A, Ishikawa N, Yasui W, Inai K, Nishimura H, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y
    • Journal Title

      Clin Cancer Res 13(22 Pt 1)

      Pages: 6624-6631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590899
  • [Journal Article] Prognostic Value of Circulating KL-6 in Idiopathic Pulmonary Fibrosis.2006

    • Author(s)
      Yokoyama A, Kondo K, Nakajima M, Matsushima T, Takahashi T, Nishimura M, Bando M, Sugiyama Y, Totani Y, Ishizaki T, Ichiyasu H, Suga M, Hamada H, Kohno N.
    • Journal Title

      Respirology 11

      Pages: 164-168

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590747
  • [Journal Article] Air Trapping in Patients with Asthma May Represent Remodeling of Small Airways.2006

    • Author(s)
      Ito R, Yokoyama A, Hamada H, Yasuhara Y, Kohno N, Higaki J.
    • Journal Title

      J Asthma 43

      Pages: 25-29

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590747
  • [Journal Article] Anti-tumor effect of the anti-KL-6/MUCI monoclonal antibody through exposure of surface molecules by MUC1 capping.2006

    • Author(s)
      Doi M, Yokoyama A, Kondo K, Ohnishi H, Ishikawa N, Hattori N, Kohno N.
    • Journal Title

      Cancer Sci 97

      Pages: 420-429

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590747
  • [Journal Article] KL-6, a Human MUCI Mucin, Promotes Proliferation and Survival of Lung Fibroblasts.2005

    • Author(s)
      Ohshimo S, Yokoyama A, Hattori N, Ishikawa N, Hirasawa Y, Kohno N.
    • Journal Title

      Biochem Biophys Res Comm 338

      Pages: 1845-1852

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590747
  • [Journal Article] Circulating aminopeptidase N/CD13 is an independent prognostic factor in patients with non-small cell lung cancer.2005

    • Author(s)
      Murakami H, Yokoyama A, Kondo K, Nakanishi S, Kohno N, Miyake M.
    • Journal Title

      Clin Cancer Res 11

      Pages: 8674-8679

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590747
  • [Journal Article] Adoptive Transfer of Th1 Clones Inhibits Eosinophilic Inflammation and Airway Hyperresponsiveness in a Murine Model of Asthma2005

    • Author(s)
      H, Hamada H, Nakajima M, Kohno N, Higaki J.
    • Journal Title

      Eur Respir J 25

      Pages: 653-659

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590747
  • [Journal Article] Polymorphism of MUC1 mucin gene is associated with susceptibility and prognosis of lung adenocarcinoma.2005

    • Author(s)
      Mitsuta K, Yokoyama A, Kondo K, Nakajima M, Kohno N.
    • Journal Title

      Oncol Rep 14

      Pages: 185-189

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590747
  • [Journal Article] Sialylated carbohydrate antigen KL-6.2004

    • Author(s)
      Kohno N
    • Journal Title

      Nippon Rinsho 62・S11

      Pages: 321-324

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370197
  • [Journal Article] Circulating Natural Killer T Cells in Patients with Asthma Irifune K, Yokoyama A, Sakai K, Watanabe A, Katayama H, Ohnishi2004

    • Author(s)
      Ikegami Y, Yokoyama A, Haruta Y, Hiyama K, Mendoza C, Kohno K.
    • Journal Title

      J Asthma 41

      Pages: 877-882

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590747
  • [Journal Article] シアル化糖鎖抗原KL-62004

    • Author(s)
      河野修興
    • Journal Title

      日本臨床広範囲血液・尿化学検査免疫学的検査-その数値をどう読むか- 62・S11

      Pages: 321-324

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370197
  • [Journal Article] シアル化糖鎖抗原KL-62004

    • Author(s)
      河野修興
    • Journal Title

      日本臨床 広範囲 血液・尿化学検査免疫学的検査-その数値をどう読むか- 62・S11

      Pages: 321-324

    • Data Source
      KAKENHI-PROJECT-14370197
  • [Journal Article] Krebs von den Lungen-6 (KL-6) is a Prognostic Biomarker for Non-Small Cell Lung Cancer.

    • Author(s)
      Tanaka S, Hattori N, Ishikawa N, Shoda H, Takano A, Nishino R, Okada M, Arihiro K, Inai K, Hamada H, Yokoyama A, Kohno N.
    • Journal Title

      Int J Cancer (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Surfactant protein A and KL-6 are elevated in the induced sputum of COPD ; a sequential sputum analysis.

    • Author(s)
      Ishikawa N, Hattori N, Tanaka S, Horimasu Y, Haruta Y, Yokoyama A, Kohno N, Kinnula VL.
    • Journal Title

      Respiration (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Journal Article] Productive cough is an independent risk factor for the development of COPD in former smokers.

    • Author(s)
      Yamane T, Hattori N, Kitahara Y, Haruta Y, Sasaki H, Yokoyama A, Kohno N
    • Journal Title

      Respirology 2010 15

      Pages: 313-318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Journal Article] Overexpression of Suppressor of Cytokine Signaling-5 Augments Eosinophilic Airway Inflammation in Mice

    • Author(s)
      Ohshima M, Yokoyama A, Ohnishi H, Hamada H, Kohno N, Higaki J, Naka T.
    • Journal Title

      Clin Exp Allergy (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590747
  • [Journal Article] Erlotinib efficacy and cerebrospinal fluid concentration in lung adenocarcinoma patients developing leptomeningeal metastases during gefitinib therapy.

    • Author(s)
      Masuda T, Hattori N, Hamada A, Iwamoto H, Ohshimo S, Kanehara M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Kohno N.
    • Journal Title

      Cancer Chemoth Pharm (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Patent] 癌の病態進行を予測する方法2005

    • Inventor(s)
      河野 修興, 満田 一博 他3名
    • Industrial Property Rights Holder
      広島大学
    • Industrial Property Number
      2005-060726
    • Filing Date
      2005-03-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370197
  • [Patent] 癌の病態進行を予測する方法2005

    • Inventor(s)
      河野修興, 満田一博, 他3名
    • Industrial Property Rights Holder
      広島大学
    • Industrial Property Number
      2005-060726
    • Filing Date
      2005-03-04
    • Data Source
      KAKENHI-PROJECT-14370197
  • [Presentation] MUC1 gene polymorphism and serum KL-6 in lung adenocarcinoma.2015

    • Author(s)
      Horimasu Y, Ishikawa N, Tanaka S, Iwamoto H, Ohshimo S, Fujitaka K, Hattori N, Hamada H, Kohno N.
    • Organizer
      European Respiratory Society International Congress 2015
    • Place of Presentation
      アムステルダム(オランダ)
    • Year and Date
      2015-09-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] 特発性肺線維症における血清バイオマーカーの意義に関する検討2015

    • Author(s)
      濵井宏介、岩本博志、石川暢久、大下慎一郎、濱田泰伸、堀益靖、藤高一慶、村井博、服部登、河野修興
    • Organizer
      第55回日本呼吸器学会学術講演会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2015-04-17
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] 日本人の間質性肺炎急性増悪症例における体外式膜型人工肺(ECMO)の有用性2015

    • Author(s)
      大下慎一郎, 木田佳子, 太田浩平, 京道人, 島谷竜俊, 儀賀普嗣, 小山和宏, 稲川嵩紘, 鈴木慶, 山賀聡之, 田邉優子, 大谷直嗣, 貞森拓磨, 宇根一暢, 津村龍, 岩崎泰昌, 廣橋伸之, 服部登, 河野修興, 谷川攻一
    • Organizer
      第37回日本呼吸療法医学会総会
    • Place of Presentation
      国立京都国際会館館(京都)
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] Comparative analysis of multiple gene polymorphisms for acute exacerbation of idiopathic pulmonary fibrosis.2015

    • Author(s)
      Ohshimo S, Yamaoka C, Horimasu Y, Iwamoto H, Fujitaka K, Hamada H, Hattori N, Hirohashi N, Tanigawa K, Bonella F, Guzman J, Costabel U, Kohno N.
    • Organizer
      European Respiratory Society International Congress 2015
    • Place of Presentation
      アムステルダム(オランダ)
    • Year and Date
      2015-09-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] HRCT Findings as a Predictive Factor for Acute Exacerbation of Idiopathic Pulmonary Fibrosis.2015

    • Author(s)
      Yamaoka C, Horimasu Y, Iwamoto H, Ohshimo S, Fujitaka K, Murai H, Hattori N, Hamada H, Kohno N.
    • Organizer
      第55回日本呼吸器学会学術講演会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2015-04-17
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] Growth differentiation factor-15 (GDF-15) as prognostic factor in German patients with idiopathic pulmonary fibrosis.2015

    • Author(s)
      Ohshimo S, Hamai K, Bonella F, Yamaoka C, Horimasu Y, Iwamoto H, Ishikawa N, Fujitaka K, Murai H, Hamada H, Hattori N, Hirohashi N, Tanigawa K, Guzman J, Costabel U, Kohno N.
    • Organizer
      American Thoracic Society International Conference 2015
    • Place of Presentation
      デンバー(アメリカ合衆国)
    • Year and Date
      2015-05-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] Growth differentiation factor-15 (GDF-15) as prognostic factor in Caucasians with idiopathic pulmonary fibrosis.2015

    • Author(s)
      Ohshimo S, Hamai K, Bonella F, Yamaoka C, Horimasu Y, Iwamoto H, Ishikawa N, Fujitaka K, Murai H, Hamada H, Hattori N, Hirohashi N, Tanigawa K, Guzman J, Costabel U, Kohno N.
    • Organizer
      第55回日本呼吸器学会学術講演会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2015-04-17
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] 放射線肺線維症マウスモデルにおける肺の線維化とPAI-1(plasminogen activator inhibitor-1)の関与についての検討2015

    • Author(s)
      塩谷咲千子、服部登、平野有美、妹尾直、益田武、堀益靖、中島拓、岩本博志、藤高一慶、河野修興
    • Organizer
      第55回日本呼吸器学会学術講演会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2015-04-17
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] Ethnic difference in the incidence of acute exacerbation in idiopathic pulmonary fibrosis2013

    • Author(s)
      Ohshimo S, Ishikawa N, Horimasu Y, Fujitaka K, Haruta Y, Murai H, Hattori N, Bonella F, Kohno N, Guzman J, Costabel U.
    • Organizer
      American Thoracic society international Conference 2013
    • Place of Presentation
      フィラデルフィア、アメリカ
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Discovery and clinical application of KL-6, a circulating biomarker for interstitial lung diseases.2013

    • Author(s)
      Kohno N.
    • Organizer
      2013 European Respiratory Society Annual Congress
    • Place of Presentation
      バルセロナ、スペイン
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] 3. Ethnic difference in the incidence of acute exacerbation in idiopathic pulmonary fibrosis.2013

    • Author(s)
      Ohshimo S, Ishikawa N, Horimasu Y, Fujitaka K, Haruta Y, Murai H, Hattori N, Bonella F, Kohno N, Guzman J, Costabel U.
    • Organizer
      American Thoracic society international Conference 2013
    • Place of Presentation
      フィラデルフィア、アメリカ
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] MUC1 gene polymorphisms are associated with serum KL-6 levels and pulmonary dysfunction in pulmonary alveolar proteinosis.2013

    • Author(s)
      Ohshimo S, Horimasu Y, Bonella F, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Hirohashi N, Hattori N, Tanigawa K, KohnoN, Guzman J, Costabel U.
    • Organizer
      2013 European Respiratory Society Annual Congress
    • Place of Presentation
      バルセロナ、スペイン
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Gene expression profiles of chronic hypersensitivity pneumonitis: Molecular signatures of pulmonary fibrosis.2013

    • Author(s)
      Ishikawa N, Taniwaki M, Horimasu Y, Iwamoto H, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N, Kohno N.
    • Organizer
      American Thoracic society international Conference 2013
    • Place of Presentation
      フィラデルフィア、アメリカ
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] KL-6, SP-D and MMP-7 as serum biomarkers for early detection of interstitial lung diseases.2013

    • Author(s)
      Ishikawa N, Yoshioka K, Horimasu Y, Iwamoto H, Ohshimo S, Hattori N, Kohno N.
    • Organizer
      2013 European Respiratory Society Annual Congress
    • Place of Presentation
      バルセロナ、スペイン
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] 4. KL-6, SP-D and MMP-7 as serum biomarkers for early detection of interstitial lung diseases.2013

    • Author(s)
      Ishikawa N, Yoshioka K, Horimasu Y, Iwamoto H, Ohshimo S, Hattori N, Kohno N.
    • Organizer
      2013 European Respiratory Society Annual Congress
    • Place of Presentation
      バルセロナ、スペイン
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] Difference of serum SP-D levels between German and Japanese are associated with SFTP gene polymorphisms.2013

    • Author(s)
      Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Bonella F, Ohshimo S, Guzman J, Costabel U, KohnoN.
    • Organizer
      American Thoracic society international Conference 2013
    • Place of Presentation
      フィラデルフィア、アメリカ
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] Antitumor effect of a humanized antibody against aminopeptidase N in mouse tumor models2013

    • Author(s)
      Akita S, Hattori N, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Kohno N
    • Organizer
      18th congress of the Asian Pacific Society of Respirology
    • Place of Presentation
      横浜
    • Year and Date
      2013-11-11
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] MUC1 gene polymorphisms are associated with serum KL-6 levels and pulmonary dysfunction in pulmonary alveolar proteinosis.2013

    • Author(s)
      Ohshimo S, Horimasu Y, Bonella F, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Hirohashi N, Hattori N, Tanigawa K, KohnoN, Guzman J, Costabel U.
    • Organizer
      2013 European Respiratory Society Annual Congress
    • Place of Presentation
      バルセロナ、スペイン
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] Difference of serum SP-D levels between German and Japanese are associated with SFTP gene polymorphisms.2013

    • Author(s)
      Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Bonella F, Ohshimo S, Guzman J, Costabel U, KohnoN.
    • Organizer
      American Thoracic society international Conference 2013
    • Place of Presentation
      フィラデルフィア、アメリカ
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Gene expression profiles of chronic hypersensitivity pneumonitis: Molecular signatures of pulmonary fibrosis.2013

    • Author(s)
      Ishikawa N, Taniwaki M, Horimasu Y, Iwamoto H, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N, Kohno N.
    • Organizer
      American Thoracic society international Conference 2013
    • Place of Presentation
      フィラデルフィア、アメリカ
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Discovery and clinical application of KL-6, a circulating biomarker for interstitial lung diseases2013

    • Author(s)
      Kohno N
    • Organizer
      2013 European Respiratory Society Annual Congress
    • Place of Presentation
      Barcelona Spain
    • Year and Date
      2013-09-07
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Discovery and clinical application of KL-6, a circulating biomarker for interstitial lung diseases2013

    • Author(s)
      Kohno N
    • Organizer
      European Respiratory Society Annual Congress
    • Place of Presentation
      バルセロナ、スペイン
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] KL-6 is a useful serum biomarker for early detection of interstitial lung disease.2012

    • Author(s)
      Kohno N, Ishikawa N, Deguchi N, Iwamoto H, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N.
    • Organizer
      European Respiratory Society Annual Congress
    • Place of Presentation
      Vienna(オーストリア)
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Different serum cut-off values of KL-6 for German and Japanese to diagnose iIdiopathic interstitial pneumonias are related to different Mucin-1 gene polymorphisms.2012

    • Author(s)
      Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Yoshioka K, Bonella F, Ohshimo S, Guzman J, Kohno N, Costabel U.
    • Organizer
      American Thoracic Society International Conference
    • Place of Presentation
      San Francisco(アメリカ.)
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Gene expression profiles of idiopathic interstitial pneumonias: Identification of disease-specific diagnostic markers and molecular therapeutic targets.2012

    • Author(s)
      Ishikawa N, Hattori N, Taniwaki M, Horimasu Y, Matsuda T, Kohno N.
    • Organizer
      European Respiratory Society Annual Congress
    • Place of Presentation
      Vienna(オーストリア)
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] KL-6 and CCL18 as predictors for acute exacerbation in idiopathic pulmonary fibrosis.2012

    • Author(s)
      Ohshimo S , Horimasu Y, Bonella F, Ishikawa N, Hattori N, Tanigawa K, Kohno N, Guzman J, Costabel U.
    • Organizer
      American Thoracic Society International Conference
    • Place of Presentation
      San Francisco(アメリカ.)
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Different cutoff values of serum SP-D for German and Japanese to diagnose idiopathic interstitial pneumonias are related to different SFTPD gene polymorphisms.2012

    • Author(s)
      Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Yoshioka K, Bonella F, Ohshimo S, Guzman J, Costabel U, Kohno N.
    • Organizer
      European Respiratory Society Annual Congress
    • Place of Presentation
      Vienna(オーストリア)
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] nterferon (-alpha, -beta, and -omega) receptor 2 (IFNAR2) is a prognostic biomarker for lung cancer.2011

    • Author(s)
      Ishikawa N, Hattori N, Tanaka S, Horimasu Y, Yokoyama A, Kohno N.
    • Organizer
      European Respiratory Society Annual Congress
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Serum KL-6 is a useful diagnostic and prognostic biomarker in idiopathic interstitial pneumonia in German patients.2011

    • Author(s)
      Horimasu Y, Ohshimo S, Ishikawa N, Tanaka S, Yoshioka K, Bonella F, Hattori N, Kohno N, Guzman J, Costabel U.
    • Organizer
      American Thoracic Society International Conference
    • Place of Presentation
      Denver, U.S.A.
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Serum SP-A and SP-D: different cutoff values for German and Japanese patients to diagnose idiopathic interstitial pneumonia.2011

    • Author(s)
      Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Yoshioka K, Ohshimo S, Bonella F, Guzman J, Costabel U, Kohno N.
    • Organizer
      European Respiratory Society Annual Congress
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Krebs von den lungen-6 (KL-6) is a useful biomarker for life threatening EGFR-TKI related interstitial lung disease2011

    • Author(s)
      Kawase S, Hattori N, Ishikawa N, Horimasu Y, Furonaka O, Isobe T, Hamada H, Yokoyama A, Kohno N
    • Organizer
      American Thoracic Society International Conference
    • Place of Presentation
      Denver, U.S.A.
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Reliability of ATS/ERS criteria for the diagnosis of idiopathic pulmonary fibrosis.2011

    • Author(s)
      Ohshimo S, Bonella F, Tanigawa K, Kohno N, Guzman J, Costabel U.
    • Organizer
      European Respiratory Society Annual Congress
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected nonsmall cell lung cancer2011

    • Author(s)
      Tanaka S, Ishikawa N, Hattori N, Hamada H, Yokoyama A, Kohno N
    • Organizer
      2011 European Respiratory Society Annual Congress
    • Place of Presentation
      Amsterdam, Netherlands
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-23659433
  • [Presentation] EGFR-TKIによる致死的薬剤性肺障害におけるKL-6値の有用性の検討2010

    • Author(s)
      河瀬成穂, 服部登, 石川暢久, 高野淳, 堀益靖, 礒部威, 濱田泰伸, 横山彰仁, 河野修興
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Presentation] Krebs von den Lungen-6(KL-6) is a Serologic and Prognostic Biomarker and a Possible Therapeutic Target for IPF (International Symposium)2009

    • Author(s)
      河野修興
    • Organizer
      第48回日本呼吸器学会総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Presentation] 外科的切除を行った非小細胞性肺癌におけるKL-6/MUC1の検討2009

    • Author(s)
      田中惣之輔, 石川暢久, 吉岡宏治, 藤高一慶, 春田吉則, 村井博, 服部登, 河野修興
    • Organizer
      第49回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Presentation] 間質性肺炎と肺癌2009

    • Author(s)
      河野修興
    • Organizer
      日本内科学会総会
    • Place of Presentation
      東京・東京国際フォーラム
    • Year and Date
      2009-04-10
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Presentation] 間質性肺炎と肺癌2009

    • Author(s)
      河野修興
    • Organizer
      日本内学会総会
    • Place of Presentation
      東京都
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Presentation] 非腫瘍性呼吸器疾患におけるsialyl Lewis aを有するKL-6の検討2009

    • Author(s)
      吉岡宏治, 石川暢久, 稲田順也, 田中惣之輔, 大下慎一郎, 長尾早江子, 春田吉則, 村井博, 服部登, 河野修興
    • Organizer
      第49回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Presentation] Gefitinib使用患者における血清KL-6値モニタリングの意義2008

    • Author(s)
      石川暢久, 服部登, 横山彰仁, 吉岡宏治, 田中惣之輔, 河瀬成穂, 藤高一慶, 濱田泰伸, 河野修興
    • Organizer
      第48回日本呼吸器学会総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Presentation] Krebs von den Lungen-6 (KL-6)is a Serologic and Prognostic Biomarker and a Possible Therapeutic Target for IPF (International Symposium)2008

    • Author(s)
      河野修興
    • Organizer
      第48回日本呼吸器学会総会
    • Place of Presentation
      名古屋国際会議場・名古屋市
    • Year and Date
      2008-06-17
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Presentation] KL-6の発見から臨床応用まで(シンポジウムI : 糖質科学とバイオマーカー)2008

    • Author(s)
      河野修興
    • Organizer
      第28回日本糖質学会年会
    • Place of Presentation
      つくば国際会議場・つくば市
    • Year and Date
      2008-08-18
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Presentation] KL-6の発見から臨床応用まで2008

    • Author(s)
      河野修興
    • Organizer
      第28回日本糖質学会年会
    • Place of Presentation
      つくば
    • Year and Date
      2008-08-18
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Presentation] Cancer-testis Antigen LY6K is a Serologic Biomarker and a Therapeutic Target for Lung and Esophageal Carcinomas.2008

    • Author(s)
      Ishikawa N, Takano A, Miyagi Y, Yasui W, Inai K, Hosokawa M, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20590924
  • [Presentation] 薬物性肺障害の種類と診断の要点2007

    • Author(s)
      河野 修興
    • Organizer
      第104回日本内科学会総会
    • Place of Presentation
      大阪市
    • Year and Date
      2007-04-03
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Presentation] 呼吸はメタボリック症候群克服のキーファクターである2007

    • Author(s)
      河野 修興
    • Organizer
      第61回日本交通医学会総会
    • Place of Presentation
      広島
    • Year and Date
      2007-06-09
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Presentation] 血清マーカーによる薬剤性肺炎の診断2007

    • Author(s)
      河野 修興
    • Organizer
      第49回日本内科学会東北支部主催生涯教育講演会
    • Place of Presentation
      仙台
    • Year and Date
      2007-06-16
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Presentation] 薬物性肺障害の種類と診断の要点2007

    • Author(s)
      河野修興
    • Organizer
      第104回日本内科学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19390224
  • [Presentation] 3.Annual decline in lung function can predict the prognosis of patients with chronic hypersensitivity pneumonia

    • Author(s)
      Horimasu Y, Ishikawa N, Nakashima T, Iwamoto H, Senoo T, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N, Kohno N
    • Organizer
      American Thoracic society international Conference
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2014-05-16 – 2014-05-21
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] 13.Angiopoietin-2 Gene Polymorphism as Prognostic Factor in Caucasians with Idiopathic Pulmonary Fibrosis

    • Author(s)
      Ohshimo S, Horimasu Y, Bonella F, Iwamoto H, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Hattori N, Hirohashi N, Tanigawa K, Guzman J, Costabel U, Kohno N
    • Organizer
      European Respiratory Society Annual Congress
    • Place of Presentation
      Munich, Germany
    • Year and Date
      2014-09-06 – 2014-09-10
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] 1.Gene expression profiles of idiopathic interstitial pneumonias: Molecular signatures of pulmonary fibrosis

    • Author(s)
      Ishikawa N, Masuda T, Horimasu Y, Hattori N, Ohshimo S, Kohno N
    • Organizer
      American Thoracic society international Conference
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2014-05-16 – 2014-05-21
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] 2.Impact of Ethnic Difference and TERT Gene Polymorphisms in the Acute Exacerbation of Idiopathic Pulmonary Fibrosis

    • Author(s)
      Ohshimo S, Ishikawa N, Horimasu Y, Fujitaka K, Haruta Y, Murai H, Hattori N, Bonella F, Guzman J, Costabel U, Kohno N
    • Organizer
      American Thoracic society international Conference
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2014-05-16 – 2014-05-21
    • Data Source
      KAKENHI-PROJECT-25253057
  • [Presentation] 1.Bronchoalveolar lavage cellular pattern can predict the prognosis of patients with chronic hypersensitivity pneumonia

    • Author(s)
      Horimasu Y, Ishikawa N, Nakashima T, Senoo T, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N, Kohno N
    • Organizer
      第54回日本呼吸器学会学術講演会
    • Place of Presentation
      大阪
    • Year and Date
      2014-04-25 – 2014-04-27
    • Data Source
      KAKENHI-PROJECT-25253057
  • 1.  YOKOYAMA Akihito (30191513)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 28 results
  • 2.  HATTORI Noboru (00283169)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 89 results
  • 3.  ISHIKAWA Nobuhisa (90423368)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 98 results
  • 4.  MIYAKE Masayuki (90250076)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  IWAMOTO Hiroshi (60457398)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 6.  HIYAMA Keiko (60253069)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KONDO Keiichi (20332827)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 8.  SAKAI Mizu (40403886)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  OHNISHI Hiroshi (90553876)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KONDOH Tomohiro (40444690)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  INOUE Yoshikazu (90240895)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  NAKA Tetsuji (30303936)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  HAMADA Hironobu (80314954)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  NAKAJIMA Masamitsu (20198097)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  田口 禎一郎 (80216829)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  尾崎 庄一郎 (80145060)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  渡辺 裕 (40114722)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  粟井 和夫 (30294573)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  大下 慎一郎 (50508132)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 23 results
  • 20.  中島 拓 (90643792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 21.  平澤 泰 (90284405)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  前田 裕行 (80274075)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  秋山 實利
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  ITO Hidemi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  TAKANO Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  醍醐 弥太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  中村 卓郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  中村 祐輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  土屋 永寿
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  加藤 秀樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  樋野 興夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  高野 洋志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  中村 直哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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