ISHIKAWA Nobuhisa 石川暢久

Researcher Number	90423368
Other IDs	https://orcid.org/0000-0002-0208-2180
Affiliation (based on the past Project Information) *help	2014: 広島大学, その他の研究科, 講師 2013: 広島大学, 医歯薬保健学研究院, 講師 2013: 広島大学, 大学院医歯薬保健学研究院, 講師 2012 – 2013: 広島大学, 医歯薬保健学研究院(医), 講師 2011: 広島大学, 医歯(薬)学総合研究科, 講師 … More 2007 – 2010: Hiroshima University, 大学院・医歯薬学総合研究科, 助教 2009: 広島大学, 附属病院, 助教 2007: 広島大学, 医歯薬学総合研究科, 助教 2006: 広島大学, 病院, 助手 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator バイオマーカー / 肺癌 / マイクロアレイ / SP-D / SP-A / KL-6 / 国際情報交換 / 分子標的治療薬 / 間質性肺炎 / 肺がん … More / 人種差 / ムチン / 慢性閉塞性肺疾患 / 肺線維症 / TGF-α / Amphiregulin / ECLIA / Gefitinib / ゲノム / 癌 … More Except Principal Investigator 分子標的治療薬 / KL-6 / 肺癌 / マイクロアレイ / 人種差 / バイオマーカー / 間質性肺炎 / SNP / 成人呼吸促迫症候群 / 汎発性血管内凝固症候群 / セレクチン / 急性呼吸窮迫症候群 / MUC1ムチン / GFP / 気管支喘息 / 肺線維症 / RNA干渉 / 糖鎖 / ゲノム / 医療・福祉 / 薬剤性肺障害 / 呼吸器病学 Less

マルチオミクス解析による間質性肺炎の新規バイオマーカーの開発と治療戦略の確立Principal Investigator
- Principal Investigator
  
  石川暢久
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hiroshima University
国際共同研究による間質性肺炎の新規バイオマーカーの開発と創薬の試み
- Principal Investigator
  
  河野修興
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hiroshima University
Identification of novel disease-specific diagnostic markers and therapeutic targets for interstitial pneumoniasPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Nobuhisa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hiroshima University
Anti KL-6 antibody enhances the effects of molecular targeted drug
- Principal Investigator
  
  KOHNO Nobuoki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hiroshima University
The elucidation of an ethnic difference of lung cancer and the development of a new therapyPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Nobuhisa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hiroshima University
Comparative studies of a clinical features and genomic analysis in patients with interstitial lung disease and drug induced lung injury
- Principal Investigator
  
  KOHNO Nobuoki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hiroshima University
Application of RNA interference for therapeutic approach to refractory respiratory diseases
- Principal Investigator
  
  HATTORI Noboru
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hiroshima University
Clinicopathological role of kl-6/muc1 with selectin ligand
- Principal Investigator
  
  YOKOYAMA Akihito
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kochi University
高感度の電気化学免疫化学発光法によるGefitinib血清診断システムの開発Principal Investigator
- Principal Investigator
  
  石川暢久
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hiroshima University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] 間質性肺疾患診療マニュアル・改訂第2版2014
- Author(s)
  石川暢久，河野修興
- Total Pages
  403
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23591148
[Book] 間質性肺疾患診療マニュアル・改訂第2版2014
- Author(s)
  石川暢久,河野修興
- Publisher
  南江堂 (KL-6)
- Data Source
  KAKENHI-PROJECT-23591148
[Book] 肺癌腫瘍マーカーの判読のポイント2013
- Author(s)
  石川暢久，河野修興
- Total Pages
  713
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23591148
[Book] 肺癌腫瘍マーカーの判読のポイント.検査診断学への展望2013
- Author(s)
  石川暢久,河野修興
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23591148
[Book] 臨床病態学2013
- Author(s)
  石川暢久，河野修興
- Total Pages
  641
- Publisher
  NOUVELLE HIROKAWA
- Data Source
  KAKENHI-PROJECT-23591148
[Book] 薬剤性肺障害.臨床病態学1巻第2版2013
- Author(s)
  石川暢久,河野修興
- Publisher
  ヌーベルヒロカワ
- Data Source
  KAKENHI-PROJECT-23591148
[Book] 臨床病態学1巻2013
- Author(s)
  石川暢久，河野修興
- Total Pages
  641
- Publisher
  ヌーベルヒロカワ
- Data Source
  KAKENHI-PROJECT-23591148
[Book] 肺がん.かんの浸潤・転移2011
- Author(s)
  石川暢久,河野修興
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-23591148
[Book] かんの浸潤・転移2011
- Author(s)
  石川暢久，河野修興．
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-23591148
[Book] がんの浸潤・転移2011
- Author(s)
  石川暢久，河野修興
- Total Pages
  241
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-23659433
[Book] 間質性肺疾患診療マニュアル2010
- Author(s)
  石川暢久, 河野修興
- Total Pages
  329
- Publisher
  KL-6
- Data Source
  KAKENHI-PROJECT-20590924
[Book] KL-6.間質性肺疾患診療マニュアル2010
- Author(s)
  石川暢久, 河野修興
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-20590924
[Book] がん化学療法・分子標的治療 update2009
- Author(s)
  石川暢久, 河野修興
- Total Pages
  736
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19390224
[Book] まんがで読み解く呼吸器症例1002009
- Author(s)
  石川暢久
- Total Pages
  284
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590924
[Book] 肺毒性・心毒性.癌化学療法update 2010-20112009
- Author(s)
  石川暢久, 河野修興
- Publisher
  中外医薬社
- Data Source
  KAKENHI-PROJECT-20590924
[Book] がん化学療法・分子標的治療 update2009
- Author(s)
  石川暢久, 河野修興
- Total Pages
  736
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590924
[Book] 呼吸器コモンディズィーズめ診療2007
- Author(s)
  石川暢久, 河野修與.
- Total Pages
  406
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-18790537
[Book] 肺癌の腫瘍マーカーで何がわかるか.(呼吸器common diseaseの診療肺癌のすべて)2007
- Author(s)
  石川暢久
- Total Pages
  406
- Publisher
  文光堂・東京
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Comparative Study of Circulating MMP-7, CCL18, KL-6, SP-A, and SP-D as Disease Markers of Idiopathic Pulmonary Fibrosis2016
- Author(s)
  Kosuke Hamai, Hiroshi Iwamoto*, Nobuhisa Ishikawa, Yasushi Horimasu, Takeshi Masuda, Shintaro Miyamoto, Taku Nakashima, Shinichiro Ohshimo, Kaznounori Fujitaka, Hironobu Hamada , Noboru Hattori, Nobuoki Kohno
- Journal Title
  
  Disease markers
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25253057
[Journal Article] Long-term pulmonary complications of chemical weapons exposure in former poison gas factory workers.2016
- Author(s)
  Nishimura Y, Iwamoto H, Ishikawa N, Hattori N, Horimasu Y, Ohshimo S, Kohno N.
- Journal Title
  
  Inhal Toxicol
  
  Volume: 28 Issue: 8 Pages: 1-6
- DOI
  10.3109/08958378.2016.1173133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-16K09541
[Journal Article] MUC5B promoter polymorphism in Japanese patients with idiopathic pulmonary fibrosis.2015
- Author(s)
  Horimasu Y, Ohshimo S, Bonella F, Tanaka S, Ishikawa N, Hattori N, Kohno N, Guzman J, Costabel U.
- Journal Title
  
  Respirology.
  
  Volume: 20 Issue: 3 Pages: 439-44
- DOI
  10.1111/resp.12466
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-25860646
[Journal Article] Effect of increasing respiratory rate on airway resistance and reactance in COPD patients.2015
- Author(s)
  Nakagawa M, Hattori N, Haruta Y, Sugiyama A, Iwamoto H, Ishikawa N, Fujitaka K, Murai H, Tanaka J, Kohno N.
- Journal Title
  
  Respirology
  
  Volume: 20 Issue: 1 Pages: 87-94
- DOI
  10.1111/resp.12387
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25253057
[Journal Article] Airway inflammation in Japanese COPD patients compared with smoking and nonsmoking controls.2015
- Author(s)
  Nobuhisa Ishikawa,1 Noboru Hattori,2 Nobuoki Kohno, Akihiro Kobayashi, Tomoyuki Hayamizu, Malcolm Johnson
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis.
  
  Volume: 10 Pages: 185-92
- DOI
  10.2147/copd.s74557
- NAID
  120006799350
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25253057
[Journal Article] Differences in serum SP-D levels between German and Japanese subjects are associated with SFTPD gene polymorphisms.2014
- Author(s)
  Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Bonella F, Ohshimo S, Guzman J, Costabel U, Kohno N
- Journal Title
  
  BMC Med Genet
  
  Volume: 15 Issue: 1 Pages: 4-4
- DOI
  10.1186/1471-2350-15-4
- NAID
  120006799353
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-25860646
[Journal Article] Baseline KL-6 predicts increased risk for acute exacerbation of idiopathic pulmonary fibrosis2014
- Author(s)
  Ohshimo S, Ishikawa N, Horimasu Y, Hattori N, Hirohashi N, Tanigawa K, Kohno N, Bonella F, Guzman J, Costabel U
- Journal Title
  
  Respir Med.
  
  Volume: 108 Issue: 7 Pages: 1031-9
- DOI
  10.1016/j.rmed.2014.04.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-25860646
[Journal Article] 第41回箱根呼吸器討論会記録呼吸器疾患の新規バイオマーカーの開発と臨床応用2014
- Author(s)
  石川暢久
- Journal Title
  
  呼吸
  
  Volume: 33 Pages: 179-188
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] 第41回箱根呼吸器討論会記録　呼吸器疾患の新規バイオマーカーの開発と臨床応用2014
- Author(s)
  石川暢久
- Journal Title
  
  呼吸
  
  Volume: 33 Pages: 179-188
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Differences in serum SP-D levels between German and Japanese subjects are associated with SFTPD gene polymorphisms2014
- Author(s)
  Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Bonella F, Ohshimo S, Guzman J, Costabel U, Kohno N
- Journal Title
  
  BMC Med Genet
  
  Volume: 15(1) Pages: 4-4
- NAID
  120006799353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] 間質性肺炎マーカーの予後も含めた臨床的意義2013
- Author(s)
  石川暢久，河野修興
- Journal Title
  
  日本胸部臨床
  
  Volume: 72
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] SK-216, an inhibitor of plasminogen activator inhibitor-1, limits tumor　progression and angiogenesis.2013
- Author(s)
  Masuda T, Hattori N, Senoo T, Akita S, Ishikawa N, Fujitaka K, Haruta Y, Murai H,　Kohno N.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 12 Issue: 11 Pages: 2378-88
- DOI
  10.1158/1535-7163.mct-13-0041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-25253057
[Journal Article] 間質性肺炎マーカーの予後も含めた臨床的意義2013
- Author(s)
  石川暢久,河野修興
- Journal Title
  
  日本胸部臨床
  
  Volume: 72
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Characteristics of inspiratory and expiratory reactance in interstitial lung disease.2013
- Author(s)
  Sugiyama A, Hattori N, Haruta Y, Nakamura I, Nakagawa M, Miyamoto S, Onari Y, Iwamoto H, Ishikawa N, Fujitaka K, Murai H, Kohno N.
- Journal Title
  
  Respir Med
  
  Volume: 107 Issue: 6 Pages: 875-82
- DOI
  10.1016/j.rmed.2013.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-25253057
[Journal Article] Different MUC1 gene polymorphisms in German and Japanese ethnicities affect serum KL-6 levels2013
- Author(s)
  Horimasu Y, Hattori N, Ishikawa N, Kawase S, Tanaka S, Yoshioka K, Yokoyama A, Kohno N, Bonella F, Guzman J, Ohshimo S, Costabel U
- Journal Title
  
  Respir Med
  
  Volume: 106 Pages: 1756-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] SK-216, an inhibitor of plasminogen activator inhibitor-1, limits tumor progression and angiogenesis2013
- Author(s)
  Masuda T, Hattori N, Senoo T, Akita S, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Kohno N
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 12 Pages: 2378-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659433
[Journal Article] Different MUC1 gene polymorphisms in German and Japanese ethnicities affect serum KL-6 levels2012
- Author(s)
  Horimasu Y, Hattori N, Ishikawa N, K awase S, Tanaka S, Yoshioka K, Yokoy ama A, Kohno N, Bonella F, Guzman J, Ohshimo S, Costabel U
- Journal Title
  
  Respir Med
  
  Volume: 106 Issue: 12 Pages: 1756-64
- DOI
  10.1016/j.rmed.2012.09.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-24659405
[Journal Article] 呼吸器疾患にかかわるバイオマーカー2012
- Author(s)
  石川暢久,服部登
- Journal Title
  
  呼吸
  
  Volume: 31 Pages: 819-821
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] KL-6が異常高値を示す肺癌の頻度2012
- Author(s)
  石川暢久,河野修興
- Journal Title
  
  日本医事新報
  
  Volume: 4613 Pages: 50-51
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Interferon (alpha, beta and omega) receptor 2 is a prognostic biomarker for lung cancer.2012
- Author(s)
  Tanaka S, Hattori N, Ishikawa N, Horimasu Y, Deguchi N, Takano A, Tomoda Y, Yoshioka K, Fujitaka K, Arihiro K, Okada M, Yokoyama A, Kohno N
- Journal Title
  
  Pathobiology
  
  Volume: 79 Pages: 24-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected non-small cell lung cancer2012
- Author(s)
  Tanaka S, Hattori N, Ishikawa N, Shoda H, Takano A, Nishino R, Okada M, Arihiro K, Inai K, Hamada H, Yokoyama A, Kohno N
- Journal Title
  
  Int J Cancer
  
  Volume: 130 Pages: 377-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected non-small cell lung cancer.2012
- Author(s)
  Tanaka S, et al.
- Journal Title
  
  International journal of cancer
  
  Volume: 130 Issue: 2 Pages: 377-387
- DOI
  10.1002/ijc.26007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390165, KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433
[Journal Article] Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases.2012
- Author(s)
  Ishikawa N, Hattori N, Yokoyama A, Kohno N.
- Journal Title
  
  Respir Investig
  
  Volume: 50 Pages: 3-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Interferon (alpha, beta and omega) receptor 2 is a prognostic biomarker for lung cancer2012
- Author(s)
  Tanaka S, Hattori N, Ishikawa N, Horimasu Y, Deguchi N, Takano A, Tomoda Y, Yoshioka K, Fujitaka K, Arihiro K, Okada M, Yokoyama A, Kohno N
- Journal Title
  
  Pathobiology
  
  Volume: 79 Issue: 1 Pages: 24-33
- DOI
  10.1159/000331230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659433
[Journal Article] Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected nonsmall cell lung cancer.2012
- Author(s)
  Tanaka S, Hattori N, Ishikawa N, Shoda H, Takano A, Nishino R, Okada M, Arihiro K, Inai K, Hamada H, Yokoyama A, Kohno N
- Journal Title
  
  Int J Cancer
  
  Volume: 130 Pages: 377-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases2012
- Author(s)
  Ishikawa N, Hattori N, Yokoyama A, Kohno N
- Journal Title
  
  Respiratory Investigation
  
  Volume: 50 Pages: 3-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Interferon (alpha, Beta and omega) receptor 2 is a prognostic biomarker for lung cancer2012
- Author(s)
  Tanaka S, Hattori N, Ishikawa N, Horimasu Y, Deguchi N, Takano A, Tomoda Y, Yoshioka K, Fujitaka K, Arihiro K, Okada M, Yokoyama A, Kohno N
- Journal Title
  
  Pathobiology
  
  Volume: 79 Pages: 24-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Different MUC1 gene polymorphisms in German and Japanese ethnicities affect serum KL-6 levels.2012
- Author(s)
  Horimasu Y, Hattori N, Ishikawa N, Kawase S, Tanaka S, Yoshioka K, Yokoyama A, Kohno N, Bonella F, Guzman J, Ohshimo S, Costabel U.
- Journal Title
  
  Respir Med
  
  Volume: 106 Pages: 1756-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases2012
- Author(s)
  Ishikawa N, Hattori N, Yokoyama A, Kohno N
- Journal Title
  
  Respir Investig
  
  Volume: 50 Issue: 1 Pages: 3-13
- DOI
  10.1016/j.resinv.2012.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-24659405
[Journal Article] Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in acute respiratory distress syndrome2011
- Author(s)
  Nakashima T, Yokoyama A, Inata J, Ishikawa N, Haruta Y, Hattori N, Kohno N
- Journal Title
  
  Chest
  
  Volume: 139(2) Pages: 296-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Ageing and smoking contribute to plasma surfactant proteins and protease imbalance with correlations to airway obstruction2011
- Author(s)
  Ilumets H, Mazur W, Toljamo T, Louhelainen N, Toljamo T, Nieminen P, Kobayashi H, Ishikawa N, KinnulaVL
- Journal Title
  
  BMC Pulm Med
  
  Volume: 11 Pages: 19-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] KL-6 concentration in pulmonary epithelial lining fluid is a useful prognostic indicator in patients with acute respiratory distress syndrome.2011
- Author(s)
  Kondo T, Hattori N, Ishikawa N, Murai H, Haruta Y, Hirohashi N, Tanigawa K, Kohno N.
- Journal Title
  
  Respir Res
  
  Volume: 12 Issue: 1 Pages: 32-32
- DOI
  10.1186/1465-9921-12-32
- NAID
  120003692470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433
[Journal Article] Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer2011
- Author(s)
  Toyama A, Nakagawa H, Matsuda K, Ishikawa N, Kohno N, Daigo Y, Sato TA, Nakamura Y, Ueda K
- Journal Title
  
  Proteome Sci
  
  Volume: 9 Pages: 18-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] KL-6 Concentration in Pulmonary Epithelial Lining Fluid and Is a Useful Prognostic Indicator in Patients with Acute Respiratory Distress Syndrome2011
- Author(s)
  Kondo T, Hattori N, Ishikawa N, Murai H, Haruta Y, Hirohashi N, Tanigawa K, Kohno N
- Journal Title
  
  Respiratory Research
  
  Volume: 12 Pages: 32-32
- NAID
  120003692470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in acute respiratory distress syndrome.2011
- Author(s)
  Nakashima T, Yokoyama A, Inata J, Ishikawa N, Haruta Y, Hattori N, Kohno N.
- Journal Title
  
  Chest 139(2)
  
  Pages: 296-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Change in serum KL-6 level from baseline is useful for predicting life-threatening EGFR-TKIs induced interstitial lung disease2011
- Author(s)
  Kawase S, et al
- Journal Title
  
  Respir Res
  
  Volume: 12 Issue: 1 Pages: 97-97
- DOI
  10.1186/1465-9921-12-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433
[Journal Article] Levels of Surfactant proteins A and D, and KL-6 are elevated in the induced sputum of COPD ; a sequential sputum analysis2011
- Author(s)
  Ishikawa N, et al
- Journal Title
  
  Respiration
  
  Volume: 82 Issue: 1 Pages: 10-18
- DOI
  10.1159/000324539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390165, KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-24659405
[Journal Article] KL-6 Concentration in Pulmonary Epithelial Lining Fluid and Is a Useful Prognostic Indicator in Patients with Acute Respiratory Distress Syndrome.2011
- Author(s)
  Kondo T, Hattori N, Ishikawa N, Murai H, Haruta Y, Hirohashi N, Tanigawa K, Kohno N.
- Journal Title
  
  Respiratory Research 12(1)
  
  Pages: 32-32
- NAID
  120003692470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Krebs von den Lungen-6 (KL-6) is a Prognostic Biomarker for Non-SmallCell Lung Cancer2011
- Author(s)
  Tanaka S, Hattori N, Ishikawa N, Takano A, Nishino R, Shoda H, Yoshioka K, Akita S, Miyata Y, Okada M, Arihiro K, Inai K, Yokoyama A, Kohno N.
- Journal Title
  
  Int J Cancer
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] 【特発性間質性肺炎最近の進歩と展望】間質性肺炎のマーカーKL-6,SP-A,SP-D2011
- Author(s)
  石川暢久,河野修興
- Journal Title
  
  最新医学
  
  Volume: 6 Pages: 1140-5
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma2011
- Author(s)
  Ishikawa N, Mazur W, Toljamo T, Vuopala K, Rönty M, Horimasu Y, Kohno N, Kinnula VL
- Journal Title
  
  BMC Pulm Med
  
  Volume: 11 Pages: 22-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Surfactant protein A and KL-6 are elevated in the induced sputum of COPD; a sequential sputum analysis2011
- Author(s)
  Ishikawa N, Hattori N, Tanaka S, Horimasu Y, Haruta Y, Yokoyama A, Kohno N, Kinnula VL
- Journal Title
  
  Respiration
  
  Volume: 82 Pages: 10-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Surfactant protein A and KL-6 are elevated in the induced sputum of COPD ; a sequential sputum analysis2011
- Author(s)
  Ishikawa N, Hattori N, Tanaka S, Horimasu Y, Haruta Y, Yokoyama A, Kohno N, Kinnula VL.
- Journal Title
  
  Respiration
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Ageing and smoking contribute to plasma surfactant proteins and protease imbalance with correlations to airway obstruction.2011
- Author(s)
  Ilumets H, Mazur W, Toljamo T, Louhelainen N, Nieminen P, Kobayashi H, Ishikawa N, Kinnula VL.
- Journal Title
  
  BMC Pulm Med
  
  Volume: 11 Issue: 1 Pages: 19-19
- DOI
  10.1186/1471-2466-11-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Change in serum KL-6 level from baseline is useful for predicting life-threatening EGFR-TKIs induced interstitial lung disease2011
- Author(s)
  Kawase S, Hattori N, Ishikawa N, Horimasu Y, Fujitaka K, Furonaka O, Isobe T, Miyoshi S, Hamada H, Yamane T, Yokoyama A, Kohno N
- Journal Title
  
  Respir Res
  
  Volume: 12 Pages: 97-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Erlotinib efficacy and cerebrospinal fluid concentration in lung adenocarcinoma patients developing leptomeningeal metastases during gefitinib therapy2011
- Author(s)
  Masuda T, Hattori N, Hamada A, Iwamoto H, Ohshimo S, Kanehara M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Kohno N
- Journal Title
  
  Cancer Chemoth Pharm
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Ageing and smoking contribute to plasma surfactant proteins and protease imbalance with correlations to airway obstruction.2011
- Author(s)
  Ilumets H, Mazur W, Toljamo T, Louhelainen N, Toljamo T, Nieminen P, Kobayashi H, Ishikawa N, Kinnula VL.
- Journal Title
  
  BMC Pulm Med 11(1)
  
  Pages: 19-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] KL-6 Concentration in Pulmonary Epithelial Lining Fluid and Is a Useful Prognostic Indicator in Patients with Acute Respiratory Distress Syndrome.2011
- Author(s)
  Kondo T, Hattori N, Ishikawa N, Murai H, Haruta Y, Hirohashi N, Tanigawa K, Kohno N.
- Journal Title
  
  Respiratory Research
  
  Volume: 12(電子媒体)
- NAID
  120003692470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma.2011
- Author(s)
  Ishikawa N, Mazur W, Toljamo T, Vuopala K, Rönty M, Horimasu Y, Kohno N, Kinnula VL.
- Journal Title
  
  BMC Pulm Med
  
  Volume: 11 Issue: 1 Pages: 22-22
- DOI
  10.1186/1471-2466-11-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433
[Journal Article] Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma.2011
- Author(s)
  Ishikawa N, Mazur W, Toljamo T, Vuopala K, Ronty M, Horimasu Y, Kohno N, Kinnula VL.
- Journal Title
  
  BMC Pulm Med 11(1)
  
  Pages: 22-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in acute respiratory distress syndrome2011
- Author(s)
  Nakashima T, Yokoyama A, Inata J, Ishikawa N, Haruta Y, Hattori N, Kohno N
- Journal Title
  
  Chest
  
  Volume: 139 Pages: 296-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] A comprehensive peptidome profiling technology for the identification of early detection biomarkers for lung adenocarcinoma2011
- Author(s)
  Ueda K, Saichi N, Takami S, Kang D, Toyama A, Daigo Y, Ishikawa N, Kohno N, Tamura K, Shuin T, Nakayama M, Sato TA, Nakamura Y, Nakagawa H
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] 【線維化による疾患】特発性肺線維症2011
- Author(s)
  石川暢久,河野修興
- Journal Title
  
  BIO Clinica
  
  Volume: 26 Pages: 1078-84
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in ARDS2011
- Author(s)
  Nakashima T, et al
- Journal Title
  
  Chest
  
  Volume: 139 Issue: 2 Pages: 296-304
- DOI
  10.1378/chest.09-3082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390165, KAKENHI-PROJECT-23390222, KAKENHI-PROJECT-23591148, KAKENHI-PROJECT-23659433
[Journal Article] Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer2011
- Author(s)
  Nishino R, Takano A, Oshita H, Ishikawa N, Akiyama H, Ito H, Nakayama H, Miyagi Y, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y
- Journal Title
  
  Clin Cancer Res
  
  Volume: 17 Pages: 6272-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591148
[Journal Article] Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis.2010
- Author(s)
  Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Yokoyama A, Kohno N
- Journal Title
  
  Thorax 2010 65
  
  Pages: 334-340
- NAID
  120002398984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] 間質性肺炎と肺癌2010
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  癌と化学療法 37
  
  Pages: 6-9
- NAID
  10025609136
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] 間質性肺炎と肺癌2010
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  癌と化学療法
  
  Volume: 37 Pages: 6-9
- NAID
  10025609136
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Non-coding regionにおける遺伝子制御の最近の知見VNTR(variable number of tandem repeats)遺伝子多型による癌の進行度診断2010
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  Surgery Frontier
  
  Volume: 17 Pages: 56-58
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Suppression of plasminogen activator inhibitor-1 by RNA interference at tenuates pulmonary fibrosis2010
- Author(s)
  Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Yokoyama Y, Kohno N
- Journal Title
  
  Thorax
  
  Volume: 65 Pages: 334-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Hemoglobin in human lung, its loss in Pulmonary Fibrosis but not in Chronic Obstructive Pulmonary Disease2010
- Author(s)
  Ishikawa N, Ohlmeier S, Mazur W, Salmenkivi K, Myllarniemi M, Kinnula VL
- Journal Title
  
  Respiratory Research
  
  Volume: 11(電子媒体)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis.2010
- Author(s)
  Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Yokoyama Y, Kohno N.
- Journal Title
  
  Thorax 65
  
  Pages: 334-340
- NAID
  120002398984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Non-coding regionにおける遺伝子制御の最近の知見VNTR(variable number of tandem repeats)遺伝子多型による癌の進行度診断2010
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  Surgery Frontier 17
  
  Pages: 56-58
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Hemoglobin in human lung, its loss in Pulmonary Fibrosis but not in Chronic Obstructive Pulmonary Disease.2010
- Author(s)
  Ishikawa N, Ohlmeier S, Mazur W, Salmenkivi K, Myllarniemi M, Kinnula VL.
- Journal Title
  
  Respiratory Research 11(1)
  
  Pages: 165-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis.2010
- Author(s)
  Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, Fuji taka K, Haruta. Y, Murai H, Yokoyama A, Kohno N
- Journal Title
  
  Thorax 65
  
  Pages: 334-40
- NAID
  120002398984
- Data Source
  KAKENHI-PROJECT-19590898
[Journal Article] Genetic ablation of Bach1 gene reduces hyperoxic lung injury in mice : role of IL-62009
- Author(s)
  Tanimoto T, Hattori N, Senoo T, Furonaka M, Ishikawa N, et al
- Journal Title
  
  Free Radic Biol Med 179
  
  Pages: 1119-1126
- NAID
  120001700407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Airflow Limitation in Smokers is Associated with Subclinical Atherosclerosis2009
- Author(s)
  Iwamoto H, Yokoyama A, Kitahara Y, Ishikawa N, et al
- Journal Title
  
  Am J Respir Crit Care Med 179
  
  Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer2009
- Author(s)
  Takano A, Ishikawa N, Nishino R, et al
- Journal Title
  
  Cancer Res 69
  
  Pages: 6694-6703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer2009
- Author(s)
  Takano A, Ishikawa N, Nishino R, et al
- Journal Title
  
  Cancer Res 69
  
  Pages: 6694-6703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] Airflow limitation in smokers is associated with subclinical atherosclerosis.2009
- Author(s)
  Iwamoto H, Yokoyama A, Kitahara Y, Ishikawa N, Haruta Y, Yamane K, Hattori N, Hara H, Kohno N
- Journal Title
  
  Am J Respir Crit Care Med 2009 179
  
  Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] シアル化糖鎖抗原KL-62009
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  広範囲血液・尿化学検査免疫学的検査(第7版)
  
  Pages: 358-360
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: role of IL-6.2009
- Author(s)
  animoto T, Hattori N, Senoo T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Igarashi K, Kohno N
- Journal Title
  
  Free Radic Biol Med 2009 46
  
  Pages: 1119-1126
- NAID
  120001700407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] Proteomic approaches to study human parenchymal lung diseases2009
- Author(s)
  Kinnula VL, Ishikawa N, Bergmann U, Ohlmeier S.
- Journal Title
  
  Expert Review of proteomic 6
  
  Pages: 619-629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice2009
- Author(s)
  Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, et al.
- Journal Title
  
  J Pharmacol Exp Ther 328
  
  Pages: 55-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] シアル化糖鎖抗原KL-62009
- Author(s)
  石川暢久, 河野修興.
- Journal Title
  
  広範囲血液・尿化学検査, 免疫学的検査 (第7版) 1-その数値をどう読むか-
  
  Pages: 358-360
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Proteomic approaches to study human parenchymal lung diseases : Focus on Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis.2009
- Author(s)
  Kinnula VL, Ishikawa N, Bergmann U, Ohlmeier S.
- Journal Title
  
  Expert Review of proteomic 6
  
  Pages: 619-629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Airflow limitation in smokers is associated with subclinical atherosclerosis2009
- Author(s)
  I wamoto H, Yokoyama A, Kitahara Y, Ishikawa N, Haruta Y, Yamane K, Hattori N, Hara H, Kohno N
- Journal Title
  
  Am J Respir Crit Care Med 179
  
  Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590896
[Journal Article] 間質性肺炎のマーカーKL-6,SP-A,SP-D2009
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  診断と治療 97
  
  Pages: 1773-1777
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.2009
- Author(s)
  Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N
- Journal Title
  
  J Pharmacol Exp Ther 2009 328
  
  Pages: 55-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] Proteomic approaches for studying human parenchymal lung diseases.2009
- Author(s)
  Kinnula VL, Ishikawa N, Bergmann U, Ohlmeier S
- Journal Title
  
  Expert Rev Proteomics 2009 6
  
  Pages: 619-629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] Targeted serum glycoproteomics for the discovery of lung cancer-associated glyco sylation disorders using lectin-coupled ProteinChip arrays2009
- Author(s)
  Ueda K, Fukase Y, Katagiri T, Ishikawa N, et a
- Journal Title
  
  Proteomics 9
  
  Pages: 2182-2192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] 間質性肺炎のマーカー : KL-6, SP-A, SP-D2009
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  診断と治療 97
  
  Pages: 1773-1777
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.2009
- Author(s)
  F uronaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N
- Journal Title
  
  J Pharmacol Exp Ther 328
  
  Pages: 55-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590896
[Journal Article] Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome.2008
- Author(s)
  N akashima T, Yokoyama A, Ohnishi H, Hamada H, Ishikawa N, Haruta Y, Hattori N, Tanigawa K, Kohno N
- Journal Title
  
  J Intern Med 263
  
  Pages: 432-439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590896
[Journal Article] 腫瘍マーカーは肺がん診療に,どのように使われますか?2008
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  ナーシングケアQ&A 19
  
  Pages: 72-73
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] 間質性肺炎のマーカーKL-62008
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  日本胸部臨床 67
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.2008
- Author(s)
  Ishikawa N, Hattori N, Yokoyama A, Tanaka S, Nishino R, Yoshioka K, Ohshimo S, Fujitaka K, Ohnishi H, Hamada H, Arihiro K, Kohno N
- Journal Title
  
  nt J Cancer 2008 122
  
  Pages: 2612-2620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] 腫瘍マーカーのバイオマーカーとしての臨床的意義.2008
- Author(s)
  石川暢久, 河野修與.
- Journal Title
  
  医学のあゆみ肺癌UPDAIE-臨床と研究の最前線- 224
  
  Pages: 1159-63
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] 腫瘍マーカーのバイオマーカーとしての臨床的意義2008
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  医学のあゆみ「肺癌UPDATE」 224
  
  Pages: 1159-1163
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] 間質性肺炎のマーカー・KL-62008
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  呼吸器疾患の臨床検査up to date 67
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.2008
- Author(s)
  Ishikawa N, Hattori N, Yokoyama A, et. al.
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2612-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.2008
- Author(s)
  Ishikawa N, Hattori N, Yokoyama A, Tanaka S, Nishino R, Yoshioka K, Ohshimo S, Fujitaka K, Ohnishi H, Hamada H, Arihiro K, Kohno N.
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2612-2620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.2008
- Author(s)
  Ishikawa N, Hattori N, Yokoyama A, Tanaka S, Nishino R, Yoshioka K, Ohshimo S, Fujitaka K, Ohnishi H, Hamada H, Arihiro K, Kohno N.
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2612-2620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590896
[Journal Article] Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome.2008
- Author(s)
  Nakashima T, Yokoyama A, Ohnishi H, Hamada H, Ishikawa N, Haruta Y, Hattori N, Tanigawa K, Kohno N
- Journal Title
  
  J Intern Med 2008 263
  
  Pages: 432-439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] 腫瘍マーカーのバイオマーカーとしての臨床的意義2008
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  医学のあゆみ 224
  
  Pages: 1159-1163
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome.2008
- Author(s)
  Nakashima T, Yokoyama A, Ohnishi H, Hamada H, Ishikawa N, Haruta Y, Hattori N, Tanigawa K, Kohno N.
- Journal Title
  
  J Intern Med 263
  
  Pages: 432-439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Usefulness monitoring of circulating KL-6 in patients with advanced non-small cell lung cancers treated with gefitinib therapy.2008
- Author(s)
  Ishikawa N
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2612-2620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.2008
- Author(s)
  Ishikawa N, Hattori N, Yokoyama A, 他9名
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2612-20
- Data Source
  KAKENHI-PROJECT-19590898
[Journal Article] Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome.2008
- Author(s)
  Nakashima T, Yokoyama A, Ohnishi H, Hamada H, Ishikawa N, et al
- Journal Title
  
  J Intern Med 263
  
  Pages: 432-439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Anti-inflammatory effects and clinical efficacy of theophylline and tulobuterol in mild-to-moderate chronic obstructive pulmonary disease.2008
- Author(s)
  K anehara M, Yokoyama A, Tomoda Y, Shiota N, Iwamoto H, Ishikawa N, Taooka Y, Haruta Y, Hattori N, Kohno N
- Journal Title
  
  Pulm Pharmacol Ther 21
  
  Pages: 874-874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590896
[Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6(KL-6)levels to predict the clinical outcome of patients with advanced non-small cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI).2008
- Author(s)
  Ishikawa N
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2612-2620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.2008
- Author(s)
  Ishikawa N.
- Journal Title
  
  International journal of cancer 122
  
  Pages: 2612-2620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590896
[Journal Article] Anti-inflammatory effects and clinical efficacy of theophylline and tulobuterol in mild-to-moderate chronic obstructive pulmonary disease.2008
- Author(s)
  Kanehara M, Yokoyama A, Tomoda Y, Shiota N, Iwamoto H, Ishikawa N, Taooka Y, Haruta Y, Hattori N, Kohno N
- Journal Title
  
  Pulm Pharmacol Ther 2008 21
  
  Pages: 874-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] Usefulness of monitoring the circulating Krebs von den Lungen-6 (KL-6) levels to predict the clinical outcome of patients with advanced non-small cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI).2008
- Author(s)
  Ishikawa N, Hattori N, Yokoyama A, et al.
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2612-2620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Anti-inflammatory Effects and Clinical Efficacy of Theophylline and Tulobuterol in Mild to Moderate Chronic Obstructive Pulmonary Disease.2008
- Author(s)
  Kanehara M, Yokoyama A, Tomoda Y, Shiota N, Iwamoto H, Ishikawa N, et al
- Journal Title
  
  Pulm Pharmacol Ther 21
  
  Pages: 874-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] 薬剤性肺障害2008
- Author(s)
  石川暢久, 河野修興
- Journal Title
  
  リウマチ科 40
  
  Pages: 363-370
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer.2007
- Author(s)
  T aniwaki M, Takano A, Ishikawa N, Yasui W, Inai K, Nishimura H, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 6624-6631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590896
[Journal Article] Circulating KL-6/MUC1 mucin carrying sialyl Lewisa oligcsaccharide is an independent prognostic factor in patients with lung adenocarcinoma2007
- Author(s)
  Inata J, Hattori N, Yokoyama A, Ohshimo S, Doi M, Ishikawa N, Hamada H, Kohno N
- Journal Title
  
  Int J Cancer 120
  
  Pages: 2643-2649
- Data Source
  KAKENHI-PROJECT-19590898
[Journal Article] Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas.2007
- Author(s)
  Ishikawa N.
- Journal Title
  
  Cancer Res 67
  
  Pages: 11601-11611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590896
[Journal Article] Circulating KL-6/MUC1 mucin carrying sialy1 Lewis(a) oligosaccharide is an independent prognostic factor in patients with lung acenocarcinoma.2007
- Author(s)
  Inata J, Hattori N, Ishikawa N, et. al.
- Journal Title
  
  Int J Cancer 120
  
  Pages: 2643-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Activation of KIF4A as a Prognostic Biomarker and Therapeutic Target for Lung Cancer.2007
- Author(s)
  Taniwaki M, Takano A, Ishikawa N, et. al.
- Journal Title
  
  Cancer Res 13
  
  Pages: 6624-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas.2007
- Author(s)
  Ishikawa N, Takano A, Yasui W, Inai K, Nishimura H, Ito H, Miyagi Y, Nakayama H, Fujita M, Hosokawa M, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y.
- Journal Title
  
  Cancer Res 1567
  
  Pages: 11601-11611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590896
[Journal Article] Fibroblast Growth Factor Receptor 1 Oncogere Partner as a Novel Prognostic Biomarker ankl Therapeutic Target for Lung Cancer.2007
- Author(s)
  Mano Y, Takahashi K, Ishikawa N, et. al.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1902-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinonmas.2007
- Author(s)
  Ishikawa N, Takano A, Yasui W, et. al.
- Journal Title
  
  Cancer Res 67
  
  Pages: 1601-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Incrcased expression of IGF-II mRNA-binding protein 1 Is assoclated with the tumor progression in patients with lung cancer.2007
- Author(s)
  Kato T, Hayama S, Ishikawa N, et. al.
- Journal Title
  
  Clinical Cancer Res 13
  
  Pages: 434-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.2007
- Author(s)
  Suzuki C, Takahashi K, Ishikawa N, et. al.
- Journal Title
  
  Mol Cancer Thers 6
  
  Pages: 542-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Dkk1 as a novel serological and prognostic biomarker for lung and esophageal carcinomas.2007
- Author(s)
  Yamabuki T, Takano A, Ishikawa N, et. al.
- Journal Title
  
  Cancer Res 67
  
  Pages: 2517-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Activation of CDCAI-KNTC2,members of centromere protein complex,involved in pulmonary carcinogenesis.2007
- Author(s)
  Hayama S, Daigo Y, Ishikawa N, et. al.
- Journal Title
  
  Mol Cancer Thers 6
  
  Pages: 542-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas.2007
- Author(s)
  Ishikawa N
- Journal Title
  
  Cancer Research 67
  
  Pages: 11601-11611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390224
[Journal Article] Characterization of SEZ6L2 cell-surface protein as a novel histochemical and prognostic marker for lung cancer.2006
- Author(s)
  Ishikawa N
- Journal Title
  
  Cancer Science 97・8
  
  Pages: 737-745
- Data Source
  KAKENHI-PROJECT-18790537
[Journal Article] Krebs von den Lungen-6 (KL-6) is a Prognostic Biomarker for Non-Small Cell Lung Cancer.
- Author(s)
  Tanaka S, Hattori N, Ishikawa N, Shoda H, Takano A, Nishino R, Okada M, Arihiro K, Inai K, Hamada H, Yokoyama A, Kohno N.
- Journal Title
  
  Int J Cancer (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Surfactant protein A and KL-6 are elevated in the induced sputum of COPD ; a sequential sputum analysis.
- Author(s)
  Ishikawa N, Hattori N, Tanaka S, Horimasu Y, Haruta Y, Yokoyama A, Kohno N, Kinnula VL.
- Journal Title
  
  Respiration (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Journal Article] Erlotinib efficacy and cerebrospinal fluid concentration in lung adenocarcinoma patients developing leptomeningeal metastases during gefitinib therapy.
- Author(s)
  Masuda T, Hattori N, Hamada A, Iwamoto H, Ohshimo S, Kanehara M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Kohno N.
- Journal Title
  
  Cancer Chemoth Pharm (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590924
[Presentation] MUC1 gene polymorphism and serum KL-6 in lung adenocarcinoma.2015
- Author(s)
  Horimasu Y, Ishikawa N, Tanaka S, Iwamoto H, Ohshimo S, Fujitaka K, Hattori N, Hamada H, Kohno N.
- Organizer
  European Respiratory Society International Congress 2015
- Place of Presentation
  アムステルダム（オランダ）
- Year and Date
  2015-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] 特発性肺線維症における血清バイオマーカーの意義に関する検討2015
- Author(s)
  濵井宏介、岩本博志、石川暢久、大下慎一郎、濱田泰伸、堀益靖、藤高一慶、村井博、服部登、河野修興
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] Growth differentiation factor-15 (GDF-15) as prognostic factor in German patients with idiopathic pulmonary fibrosis.2015
- Author(s)
  Ohshimo S, Hamai K, Bonella F, Yamaoka C, Horimasu Y, Iwamoto H, Ishikawa N, Fujitaka K, Murai H, Hamada H, Hattori N, Hirohashi N, Tanigawa K, Guzman J, Costabel U, Kohno N.
- Organizer
  American Thoracic Society　International Conference 2015
- Place of Presentation
  デンバー（アメリカ合衆国）
- Year and Date
  2015-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] Growth differentiation factor-15 (GDF-15) as prognostic factor in Caucasians with idiopathic pulmonary fibrosis.2015
- Author(s)
  Ohshimo S, Hamai K, Bonella F, Yamaoka C, Horimasu Y, Iwamoto H, Ishikawa N, Fujitaka K, Murai H, Hamada H, Hattori N, Hirohashi N, Tanigawa K, Guzman J, Costabel U, Kohno N.
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] Ethnic difference in the incidence of acute exacerbation in idiopathic pulmonary fibrosis2013
- Author(s)
  Ohshimo S, Ishikawa N, Horimasu Y, Fujitaka K, Haruta Y, Murai H, Hattori N, Bonella F, Kohno N, Guzman J, Costabel U.
- Organizer
  American Thoracic society international Conference 2013
- Place of Presentation
  フィラデルフィア、アメリカ
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] KL-6, SP-D and MMP-7 as serum biomarkers for early detection of interstitial lung diseases2013
- Author(s)
  Ishikawa N, Yoshioka K, Horimasu Y, Iwamoto H, Ohshimo S, Hattori N, Kohno N
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] 3. Ethnic difference in the incidence of acute exacerbation in idiopathic pulmonary fibrosis.2013
- Author(s)
  Ohshimo S, Ishikawa N, Horimasu Y, Fujitaka K, Haruta Y, Murai H, Hattori N, Bonella F, Kohno N, Guzman J, Costabel U.
- Organizer
  American Thoracic society international Conference 2013
- Place of Presentation
  フィラデルフィア、アメリカ
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] Comparison of KL-6, SP-A, SP-D, 8-isoprostane, MMP-9,and TIMP-1 as serum biomarkers for patients with combined pulmonary fibrosis and emphysema2013
- Author(s)
  Ishikawa N, Matsuda T, Nakashima T, Iwamoto H, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N, Kohno N
- Organizer
  18th Congress of the Asian Pacific Society of Respirology
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] KL-6, SP-D and MMP-7 as serum biomarkers for early detection of interstitial lung diseases.2013
- Author(s)
  Ishikawa N
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] MUC1 gene polymorphisms are associated with serum KL-6 levels and pulmonary dysfunction in pulmonary alveolar proteinosis.2013
- Author(s)
  Ohshimo S, Horimasu Y, Bonella F, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Hirohashi N, Hattori N, Tanigawa K, KohnoN, Guzman J, Costabel U.
- Organizer
  2013 European Respiratory Society Annual Congress
- Place of Presentation
  バルセロナ、スペイン
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] Gene expression profiles of chronic hypersensitivity pneumonitis : Molecular signatures of pulmonary fibrosis2013
- Author(s)
  Ishikawa N, Taniwaki M, Horimasu Y, Iwamoto H, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N, Kohno N
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] Gene expression profiles of chronic hypersensitivity pneumonitis: Molecular signatures of pulmonary fibrosis.2013
- Author(s)
  Ishikawa N, Taniwaki M, Horimasu Y, Iwamoto H, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N, Kohno N.
- Organizer
  American Thoracic society international Conference 2013
- Place of Presentation
  フィラデルフィア、アメリカ
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] KL-6, SP-D and MMP-7 as serum biomarkers for early detection of interstitial lung diseases.2013
- Author(s)
  Ishikawa N, Yoshioka K, Horimasu Y, Iwamoto H, Ohshimo S, Hattori N, Kohno N.
- Organizer
  2013 European Respiratory Society Annual Congress
- Place of Presentation
  バルセロナ、スペイン
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] 4. KL-6, SP-D and MMP-7 as serum biomarkers for early detection of interstitial lung diseases.2013
- Author(s)
  Ishikawa N, Yoshioka K, Horimasu Y, Iwamoto H, Ohshimo S, Hattori N, Kohno N.
- Organizer
  2013 European Respiratory Society Annual Congress
- Place of Presentation
  バルセロナ、スペイン
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] Difference of serum SP-D levels between German and Japanese are associated with SFTP gene polymorphisms.2013
- Author(s)
  Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Bonella F, Ohshimo S, Guzman J, Costabel U, KohnoN.
- Organizer
  American Thoracic society international Conference 2013
- Place of Presentation
  フィラデルフィア、アメリカ
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] Antitumor effect of a humanized antibody against aminopeptidase N in mouse tumor models2013
- Author(s)
  Akita S, Hattori N, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Kohno N
- Organizer
  18th congress of the Asian Pacific Society of Respirology
- Place of Presentation
  横浜
- Year and Date
  2013-11-11
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] 間質性肺炎の早期発見における血清バイオマーカーの有用性に関する検討2013
- Author(s)
  石川暢久,出口奈穂子,岩本博志,大下慎一郎,藤高一慶,春田吉則,村井博,服部登,河野修興
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] MUC1 gene polymorphisms are associated with serum KL-6 levels and pulmonary dysfunction in pulmonary alveolar proteinosis.2013
- Author(s)
  Ohshimo S, Horimasu Y, Bonella F, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Hirohashi N, Hattori N, Tanigawa K, KohnoN, Guzman J, Costabel U.
- Organizer
  2013 European Respiratory Society Annual Congress
- Place of Presentation
  バルセロナ、スペイン
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] Gene expression profiles of chronic hypersensitivity pneumonitis: Molecular signatures of pulmonary fibrosis.2013
- Author(s)
  Ishikawa N
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] Difference of serum SP-D levels between German and Japanese are associated with SFTP gene polymorphisms.2013
- Author(s)
  Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Bonella F, Ohshimo S, Guzman J, Costabel U, KohnoN.
- Organizer
  American Thoracic society international Conference 2013
- Place of Presentation
  フィラデルフィア、アメリカ
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] Gene expression profiles of chronic hypersensitivity pneumonitis: Molecular signatures of pulmonary fibrosis.2013
- Author(s)
  Ishikawa N, Taniwaki M, Horimasu Y, Iwamoto H, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N, Kohno N.
- Organizer
  American Thoracic society international Conference 2013
- Place of Presentation
  フィラデルフィア、アメリカ
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] 気腫合併肺線維症におけるプロテアーゼ・アンチプロテアーゼの不均衡ならびに酸化ストレスの意義2013
- Author(s)
  石川暢久,松田智代,出口奈穂子,堀益靖,大下慎一郎,藤高一慶,春田吉則,村井博,服部登,河野修興
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] Comparison of KL-6, SP-A, SP-D, 8-isoprostane, MMP-9,and TIMP-1 as serum biomarkers for patients with combined pulmonary fibrosis and emphysema2013
- Author(s)
  Ishikawa N
- Organizer
  18th Congress of the Asian Pacific Society of Respirology
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] KL-6 is a useful serum biomarker for early detection of interstitial lung disease.2012
- Author(s)
  Kohno N, Ishikawa N, Deguchi N, Iwamoto H, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N.
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Vienna（オーストリア)
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] KL-6 is a useful serum biomarker for early detection of interstitial lung disease.2012
- Author(s)
  Kohno N, Ishikawa N, Deguchi N, Iwamoto H, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Vienna（オーストリア）
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] Different serum cut-off values of KL-6 for German and Japanese to diagnose iIdiopathic interstitial pneumonias are related to different Mucin-1 gene polymorphisms.2012
- Author(s)
  Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Yoshioka K, Bonella F, Ohshimo S, Guzman J, Kohno N, Costabel U.
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  San Francisco（アメリカ.)
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] Gene expression profiles of idiopathic interstitial pneumonias : Identification of disease-specific diagnostic markers and molecular therapeutic targets2012
- Author(s)
  Ishikawa N, Hattori N, Taniwaki M, Horimasu Y, Matsuda T, Kohno N
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] Gene expression profiles of idiopathic interstitial pneumonias: Identification of disease-specific diagnostic markers and molecular therapeutic targets.2012
- Author(s)
  Ishikawa N, Hattori N, Taniwaki M, Horimasu Y, Matsuda T, Kohno N.
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Vienna（オーストリア）
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] Gene expression profiles of idiopathic interstitial pneumonias: Identification of disease-specific diagnostic markers and molecular therapeutic targets.2012
- Author(s)
  Ishikawa N, Hattori N, Taniwaki M, Horimasu Y, Matsuda T, Kohno N.
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Vienna（オーストリア）
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] KL-6 and CCL18 as predictors for acute exacerbation in idiopathic pulmonary fibrosis.2012
- Author(s)
  Ohshimo S , Horimasu Y, Bonella F, Ishikawa N, Hattori N, Tanigawa K, Kohno N, Guzman J, Costabel U.
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  San Francisco（アメリカ.)
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] Different cutoff values of serum SP-D for German and Japanese to diagnose idiopathic interstitial pneumonias are related to different SFTPD gene polymorphisms.2012
- Author(s)
  Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Yoshioka K, Bonella F, Ohshimo S, Guzman J, Costabel U, Kohno N.
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Vienna（オーストリア）
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] nterferon (-alpha, -beta, and -omega) receptor 2 (IFNAR2) is a prognostic biomarker for lung cancer.2011
- Author(s)
  Ishikawa N, Hattori N, Tanaka S, Horimasu Y, Yokoyama A, Kohno N.
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] Serum KL-6 is a useful diagnostic and prognostic biomarker in idiopathic interstitial pneumonia in German patients.2011
- Author(s)
  Horimasu Y, Ohshimo S, Ishikawa N, Tanaka S, Yoshioka K, Bonella F, Hattori N, Kohno N, Guzman J, Costabel U.
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Denver, U.S.A.
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] Serum SP-A and SP-D: different cutoff values for German and Japanese patients to diagnose idiopathic interstitial pneumonia.2011
- Author(s)
  Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Yoshioka K, Ohshimo S, Bonella F, Guzman J, Costabel U, Kohno N.
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] KL-6/MUC1 carrying sialyl Lewisa (SLAK) is a new serum biomarker for fibrosing interstitial lung diseases.2011
- Author(s)
  Ishikawa N, Hattori N, Yoshioka K, Horimasu Y, Ohtsuki Y, Yokoyama A, Kohno N.
- Organizer
  American Thoracic Society International Conference 2011
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] Krebs von den lungen-6 (KL-6) is a useful biomarker for life threatening EGFR-TKI related interstitial lung disease2011
- Author(s)
  Kawase S, Hattori N, Ishikawa N, Horimasu Y, Furonaka O, Isobe T, Hamada H, Yokoyama A, Kohno N
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Denver, U.S.A.
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] Interferon (-alpha, -beta, and -omega) receptor 2 (IFNAR2) is a prognostic biomarker for lung cancer.2011
- Author(s)
  Ishikawa N, Hattori N, Tanaka S, Horimasu Y, Yokoyama A, Kohno N.
- Organizer
  2011 European Respiratory Society Annual Congress
- Place of Presentation
  Amsterdam, Netherland
- Data Source
  KAKENHI-PROJECT-23591148
[Presentation] Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected nonsmall cell lung cancer2011
- Author(s)
  Tanaka S, Ishikawa N, Hattori N, Hamada H, Yokoyama A, Kohno N
- Organizer
  2011 European Respiratory Society Annual Congress
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23659433
[Presentation] EGFR-TKIによる致死的薬剤性肺障害におけるKL-6値の有用性の検討2010
- Author(s)
  河瀬成穂, 服部登, 石川暢久, 高野淳, 堀益靖, 礒部威, 濱田泰伸, 横山彰仁, 河野修興
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590924
[Presentation] 呼吸器疾患の血清マーカー2009
- Author(s)
  石川暢久
- Organizer
  第44回日本呼吸器学会中国四国地方会
- Place of Presentation
  松江
- Data Source
  KAKENHI-PROJECT-20590924
[Presentation] 外科的切除を行った非小細胞性肺癌におけるKL-6/MUC1の検討2009
- Author(s)
  田中惣之輔, 石川暢久, 吉岡宏治, 藤高一慶, 春田吉則, 村井博, 服部登, 河野修興
- Organizer
  第49回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590924
[Presentation] 呼吸器疾患の血清マーカー2009
- Author(s)
  石川暢久
- Organizer
  第44回日本呼吸器学会中国四国地方会
- Place of Presentation
  松江テルサ・松江市
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-20590924
[Presentation] 非腫瘍性呼吸器疾患におけるsialyl Lewis aを有するKL-6の検討2009
- Author(s)
  吉岡宏治, 石川暢久, 稲田順也, 田中惣之輔, 大下慎一郎, 長尾早江子, 春田吉則, 村井博, 服部登, 河野修興
- Organizer
  第49回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590924
[Presentation] Cancer-testis Antigen LY6K is a Serologic Biomarker and a Therapeutic Target for Lung and Esophageal Carcinomas2008
- Author(s)
  Ishikawa N
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場・名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20590924
[Presentation] Gefitinib使用患者における血清KL-6値モニタリングの意義2008
- Author(s)
  石川暢久
- Organizer
  第48回日本呼吸器学会総会
- Place of Presentation
  神戸国際会議場・神戸市
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-20590924
[Presentation] Gefitinib使用患者における血清KL-6値モニタリングの意義2008
- Author(s)
  石川暢久, 服部登, 横山彰仁, 吉岡宏治, 田中惣之輔, 河瀬成穂, 藤高一慶, 濱田泰伸, 河野修興
- Organizer
  第48回日本呼吸器学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590924
[Presentation] Cancer-testis Antigen LY6K is a Serologic Biomarker and a Therapeutic Target for Lung and Esophageal Carcinomas.2008
- Author(s)
  Ishikawa N, Takano A, Miyagi Y, Yasui W, Inai K, Hosokawa M, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590924
[Presentation] KL-6/MUC1値は早期非小細胞肺癌の予後因子である2007
- Author(s)
  石川暢久
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18790537
[Presentation] 3.Annual decline in lung function can predict the prognosis of patients with chronic hypersensitivity pneumonia
- Author(s)
  Horimasu Y, Ishikawa N, Nakashima T, Iwamoto H, Senoo T, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N, Kohno N
- Organizer
  American Thoracic society international Conference
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] 13.Angiopoietin-2 Gene Polymorphism as Prognostic Factor in Caucasians with Idiopathic Pulmonary Fibrosis
- Author(s)
  Ohshimo S, Horimasu Y, Bonella F, Iwamoto H, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Hattori N, Hirohashi N, Tanigawa K, Guzman J, Costabel U, Kohno N
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Munich, Germany
- Year and Date
  2014-09-06 – 2014-09-10
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] 1.Gene expression profiles of idiopathic interstitial pneumonias: Molecular signatures of pulmonary fibrosis
- Author(s)
  Ishikawa N, Masuda T, Horimasu Y, Hattori N, Ohshimo S, Kohno N
- Organizer
  American Thoracic society international Conference
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] 2.Impact of Ethnic Difference and TERT Gene Polymorphisms in the Acute Exacerbation of Idiopathic Pulmonary Fibrosis
- Author(s)
  Ohshimo S, Ishikawa N, Horimasu Y, Fujitaka K, Haruta Y, Murai H, Hattori N, Bonella F, Guzman J, Costabel U, Kohno N
- Organizer
  American Thoracic society international Conference
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-25253057
[Presentation] 1.Bronchoalveolar lavage cellular pattern can predict the prognosis of patients with chronic hypersensitivity pneumonia
- Author(s)
  Horimasu Y, Ishikawa N, Nakashima T, Senoo T, Ohshimo S, Fujitaka K, Haruta Y, Murai H, Hattori N, Kohno N
- Organizer
  第54回日本呼吸器学会学術講演会
- Place of Presentation
  大阪
- Year and Date
  2014-04-25 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-25253057

1. HATTORI Noboru (00283169)

# of Collaborated Projects: 6 results

# of Collaborated Products: 74 results
2. KOHNO Nobuoki (80215194)

# of Collaborated Projects: 5 results

# of Collaborated Products: 87 results
3. YOKOYAMA Akihito (30191513)

# of Collaborated Projects: 5 results

# of Collaborated Products: 16 results
4. IWAMOTO Hiroshi (60457398)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. SAKAI Mizu (40403886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OHNISHI Hiroshi (90553876)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 粟井和夫 (30294573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 大下慎一郎 (50508132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
9. 中島拓 (90643792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

ISHIKAWA Nobuhisa 石川 暢久

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Co-Researchers

マルチオミクス解析による間質性肺炎の新規バイオマーカーの開発と治療戦略の確立Principal Investigator

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国際共同研究による間質性肺炎の新規バイオマーカーの開発と創薬の試み

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Identification of novel disease-specific diagnostic markers and therapeutic targets for interstitial pneumoniasPrincipal Investigator

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Anti KL-6 antibody enhances the effects of molecular targeted drug

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The elucidation of an ethnic difference of lung cancer and the development of a new therapyPrincipal Investigator

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Comparative studies of a clinical features and genomic analysis in patients with interstitial lung disease and drug induced lung injury

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Application of RNA interference for therapeutic approach to refractory respiratory diseases

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Clinicopathological role of kl-6/muc1 with selectin ligand

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高感度の電気化学免疫化学発光法によるGefitinib血清診断システムの開発Principal Investigator

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[Book] 間質性肺疾患診療マニュアル・改訂第2版2014

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[Book] 間質性肺疾患診療マニュアル・改訂第2版2014

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[Book] 肺癌腫瘍マーカーの判読のポイント2013

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[Book] 肺癌腫瘍マーカーの判読のポイント.検査診断学への展望2013

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[Book] 臨床病態学2013

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ISHIKAWA Nobuhisa 石川暢久