ARAI Yasuhito 新井康仁

… Alternative Names

新井康仁アライヤスヒト

Less

Researcher Number	80222727
Other IDs
External Links
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員
Affiliation (based on the past Project Information) *help	2016 – 2021: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員 2015: 国立研究開発法人国立がん研究センター, その他部局等, 研究員 2015: 国立研究開発法人国立がん研究センター, 研究所がんゲノミクス研究分野, 主任研究員 2015: 国立研究開発法人国立がん研究センター, 研究所がんゲノミクス研究分野, 主任研究員 2014: 独立行政法人国立がん研究センター, 研究所, 主任研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Medical genome science / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 分子標的 / 分子診断 / トランスクリプトーム / 胆道がん / FGFR2 / トランスクリプトーム解析 / 治療標的遺伝子 / 融合遺伝子 Except Principal Investigator 次世代シーケンサー / シングルセル解析 … More / 口腔がん / 次世代シーケンス / 循環癌細胞早期診断 / マイクロRNA / 循環癌細胞 / 腫瘍マーカー / 早期診断 / 口腔癌 / 癌の個性診断 / 分子標的治療 / 発現異常 / 治療標的分子 / 融合遺伝子 / トランスクリプトーム / 胃癌 / がん不均質性 / バイオインフォマティクス / がん細胞進化 / 腫瘍内不均質性 / 腫瘍内多様性 / 一細胞シークエンス / がんゲノム Less

Molecular classification of biliary cancer by transcriptome analysis of FFPE specimensPrincipal Investigator
- Principal Investigator
  
  Arai Yasuhito
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  National Cancer Center Japan
Decelopment of nect generation precision theraoy for oral cancer by single cell analysis of oral cancer CTCs
- Principal Investigator
  
  SUGIURA TSUYOSHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kagoshima University
Revealing cancer-cell evolution and intra-tumor heterogeneity by single-cell genome and transcriptome analysis
- Principal Investigator
  
  Kato Mamoru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical genome science
- Research Institution
  National Cancer Center Japan
Whole transcriptome analysis and novel therapeutic targets in biliary tract cancerPrincipal Investigator
- Principal Investigator
  
  Arai Yasuhito
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  National Cancer Center Japan
Identification of novel fusion genes in gastric cancer by whole transcriptome sequencing: Discovery of potential therapeutic targets for gastric cancer
- Principal Investigator
  
  Hosoda Fumie
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  National Cancer Center Japan

All 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

[Book] 医学の歩み-特集がんゲノム研究の進歩-固形がんにおける融合遺伝子の解析と治療への展開2014
- Author(s)
  新井康仁
- Total Pages
  134
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-26461040
[Journal Article] Molecular detection and clinicopathological characteristics of advanced/recurrent biliary tract carcinomas harboring the FGFR2 rearrangements: a prospective observational study (PRELUDE Study)2021
- Author(s)
  Maruki Y, Morizane C, Arai Y, Ikeda M, Ueno M, Ioka T, Naganuma A, FurukawaM, Mizuno N, Uwagawa T, Takahara N, Kanai M, Asagi A, Shimizu S, Miyamoto A, Yukisawa S, Kadokura M, Kojima Y, Furuse J, Eguchi-Nakajima T, Sudo K, Kobayashi N, Hama N, Yamanaka T, Shibata T and Okusaka T.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 56 Issue: 3 Pages: 250-250
- DOI
  10.1007/s00535-020-01735-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07956
[Journal Article] The potential application of PD-1 blockade therapy for early-stage biliary tract cancer.2020
- Author(s)
  Umemoto K, Togashi Y, Arai Y, Nakamura H, Takahashi S, Tanegashima T, Kato M, Nishikawa T, Sugiyama D, Kojima M, Gotohda N, Kuwata T, Ikeda M, Shibata T, Nishikawa H.
- Journal Title
  
  Int Immunol.
  
  Volume: 32 Issue: 4 Pages: 273-281
- DOI
  10.1093/intimm/dxz080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07035, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-18K07956, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17H06162
[Journal Article] Sarcoma with MGA-NUTM1 fusion in the lung: an emerging entity.2020
- Author(s)
  Goto T, Arai Y, Shibata T, Oyama T, Yoshida A.
- Journal Title
  
  Virchows Archiv
  
  Volume: 476 Issue: 2 Pages: 317-322
- DOI
  10.1007/s00428-019-02623-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07956, KAKENHI-PROJECT-18K15108
[Journal Article] E74-Like Factor 3 Is a Key Regulator of Epithelial Integrity and Immune Response Genes in Biliary Tract Cancer2020
- Author(s)
  Suzuki Masami、Saito-Adachi Mihoko、Arai Yasuhito、Fujiwara Yuko、Takai Erina、Shibata Shinsuke、Seki Masahide、Rokutan Hirofumi、Maeda Daichi、Horie Masafumi、Suzuki Yutaka、Shibata Tatsuhiro、Kiyono Tohru、Yachida Shinichi
- Journal Title
  
  Cancer Research
  
  Volume: 81 Issue: 2 Pages: 489-500
- DOI
  10.1158/0008-5472.can-19-2988
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07433, KAKENHI-PROJECT-18K07382, KAKENHI-PROJECT-18K07956, KAKENHI-PROJECT-19K22670
[Journal Article] Expanding the clinicopathologic and molecular spectrum of BCOR-associated sarcomas in adults.2020
- Author(s)
  Yoshida A, Arai Y, Hama N, Chikuta H, Bando Y, Nakano S, Kobayashi E, Shibahara J, Fukuhara H, Komiyama M, Watanabe SI, Tamura K, Kawai A, Shibata T.
- Journal Title
  
  Histopathology
  
  Volume: 76 Issue: 4 Pages: 509-520
- DOI
  10.1111/his.14023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07956, KAKENHI-PROJECT-18K15108, KAKENHI-PROJECT-18H02933
[Journal Article] KMT2A (MLL) fusions in aggressive sarcomas in young adults.2019
- Author(s)
  Yoshida A, Arai Y, Tanzawa Y, Wakai S, Hama N, Kawai A, Shibata T.
- Journal Title
  
  Histopathology
  
  Volume: 75 Issue: 4 Pages: 508-516
- DOI
  10.1111/his.13926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07956, KAKENHI-PROJECT-18K15108, KAKENHI-PROJECT-18H02933
[Journal Article] Epigenetic landscape influences the liver cancer genome architecture2018
- Author(s)
  Natsuko Hama, Yasushi Totoki, Fumihito Miura, Kenji Tatsuno, Mihoko Saito-Adachi, Hiromi Nakamura, Yasuhito Arai, Fumie Hosoda, Tomoko Urushidate, Shoko Ohashi, Wakako Mukai, Nobuyoshi Hiraoka, Hiroyuki Aburatani , Takashi Ito and Tatsuhiro Shibata
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 1643-1643
- DOI
  10.1038/s41467-018-03999-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07956, KAKENHI-PROJECT-17K07195
[Journal Article] Epigenetic landscape influences the liver cancer genome architecture.2018
- Author(s)
  Hama N, Totoki Y, Miura F, Tatsuno K, Saito-Adachi M, Nakamura H, Arai Y, Hosoda F, Urushidate T, Ohashi S, Mukai W, Hiraoka N, Aburatani H, Ito T, Shibata T.
- Journal Title
  
  Nat Commun.
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06916
[Journal Article] A computational tool to detect DNA alterations tailored to formalin-fixed paraffin-embedded samples in cancer clinical sequencing2018
- Author(s)
  Kato M, Nakamura H, Nagai M, Kubo T, Elzawahry A, Totoki Y, Tanabe Y, Furukawa E, Miyamoto J, Sakamoto H, Matsumoto S, Sunami K, Arai Y, Suzuki Y, Yoshida T, Tsuchihara K, Tamura K, Yamamoto N, Ichikawa H, Kohno T and Shibata T
- Journal Title
  
  Genome Medicine
  
  Volume: 10 Issue: 1 Pages: 44-44
- DOI
  10.1186/s13073-018-0547-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07956
[Journal Article] Integrated genetic and epigenetic analysis of myxofibrosarcoma2018
- Author(s)
  Koichi Ogura, Fumie Hosoda, Yasuhito Arai, Hiromi Nakamura, Natsuko Hama, Yasushi Totoki, Akihiko Yoshida, Momoko Nagai, Mamoru Kato, Erika Arakawa, Wakako Mukai, Hirofumi Rokutan, Akira Kawai, Sakae Tanaka and Tatsuhiro Shibata
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 2765-2765
- DOI
  10.1038/s41467-018-03891-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07956, KAKENHI-PROJECT-18H02933
[Journal Article] CIC Break-Apart Fluorescence In Situ Hybridization Misses a Subset of CIC-DUX4 Sarcomas: A Clinicopathological and Molecular Study2017
- Author(s)
  Yoshida A, Arai Y, Kobayashi E, Yonemori K, Ogura K, Hama N, Mukai W, Motoi T, Kawai A, Shibata T, N Hiraoka
- Journal Title
  
  Histopathology
  
  Volume: 印刷中 Issue: 3 Pages: 461-469
- DOI
  10.1111/his.13252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461040, KAKENHI-PROJECT-15K19065, KAKENHI-PROJECT-16K08680
[Journal Article] NUTM2A-CIC fusion small round cell sarcoma: A genetically distinct variant of CIC-rearranged sarcoma2017
- Author(s)
  Sugita S, Arai Y, Aoyama T, Asanuma H, Mukai W, Hama N, Emori M, Shibata T, Hasegawa T
- Journal Title
  
  Human Pathology
  
  Volume: 印刷中 Pages: 225-230
- DOI
  10.1016/j.humpath.2017.01.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461040, KAKENHI-PROJECT-16K21250
[Journal Article] NUTM2A-CIC fusion small round cell sarcoma: A genetically distinct variant of CIC-rearranged sarcoma Human Pathology2017
- Author(s)
  Sugita S, Arai Y, Aoyama T, Asanuma H, Mukai W, Hama N, Emori M, Shibata T, Hasegawa T.
- Journal Title
  
  Human Pathology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06916
[Journal Article] Heat Shock Protein 90 Is a Potential Therapeutic Target in Cholangiocarcinoma.2015
- Author(s)
  Shirota T, Ojima H, Hiraoka N, Shimada K, Rokutan H, Arai Y, Kanai Y, Miyagawa　S, Shibata T.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 14 Issue: 9 Pages: 1985-93
- DOI
  10.1038/ng.3375
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460501, KAKENHI-PROJECT-26461040, KAKENHI-PROJECT-25290074
[Journal Article] Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer.2014
- Author(s)
  Hosoda F, Inazawa J, et al.
- Journal Title
  
  Oncogene.
  
  Volume: in press Issue: 9 Pages: 1196-206
- DOI
  10.1038/onc.2014.57
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134002, KAKENHI-PROJECT-23390325, KAKENHI-PROJECT-25250019, KAKENHI-PROJECT-25290074, KAKENHI-PROJECT-25560368, KAKENHI-PROJECT-25640062, KAKENHI-PROJECT-26293304, KAKENHI-PLANNED-15H05908
[Journal Article] Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.2014
- Author(s)
  Arai Y, Totoki Y, Hosoda F, Shirota T, Hama N, Nakamura H, Ojima, Furuta K, Shimada K, Okusaka T, Kosuge T, Shibata T.
- Journal Title
  
  Hepatology
  
  Volume: 59 Issue: 4 Pages: 1427-1434
- DOI
  10.1002/hep.26890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461040
[Presentation] Molecular genetic analysis of BCOR-rearranged sarcoma2020
- Author(s)
  新井康仁、吉田朗彦、濱奈津子、知久田大史、小林英介、坂東良美、柴原純二、川井章、柴田龍弘
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07956
[Presentation] Frequency and clinicopathological characteristics of biliary tract carcinomas harboring the FGFR2-fusion gene: a prospective observational study (PRELUDE study).2019
- Author(s)
  M. Ikeda, Y. Maruki, M. Ueno, T. Ioka, A. Naganuma, M. Furukawa, N. Mizuno, T. Uwagawa, Y. Nakai, M. Kanai, A. Asagi, S. Shimizu, A. Miyamoto, S. Yukisawa, M. Kadokura, T. Yamanaka, Y. Arai, T. Shibata, C. Morizane, T. Okusaka.
- Organizer
  ESMO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07956
[Presentation] 肉腫におけるCIC遺伝子再構成の分子遺伝学的解析2018
- Author(s)
  新井康仁、吉田朗彦、濱奈津子、向和加子、知久田大史、十時泰、小倉浩一、小林英介、元井亨、川井章、平岡伸介、柴田龍弘
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07956
[Presentation] E7090, a novel and selective FGFR inhibitor, for the treatment of cholangiocarcinoma cells harboring FGFR2-fusion genes2017
- Author(s)
  Watanabe-Miyano S, Arai Y, Matsui Junji, Shibata T
- Organizer
  AACR annual meeting 2017
- Place of Presentation
  Washington Convention Center (Washington DC, USA)
- Year and Date
  2017-04-01
- Data Source
  KAKENHI-PROJECT-26461040
[Presentation] Oncogenic driver fusion genes in biliary tract cancer2016
- Author(s)
  新井康仁、中村浩実、十時泰、濱奈津子、尾島英知、細田文恵、島田和明、森実千種、奥坂拓志、柴田龍弘
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461040
[Presentation] Oncogenic driver fusion genes in biliary tract cancer2016
- Author(s)
  新井康仁、中村浩実、十時泰、濱奈津子、尾島英知、細田文恵、島田和明、森実千種、奥坂拓志、柴田龍弘
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K06916
[Presentation] High-throughput sequencing analysis uncovers actionable molecular alterations in cholangiocarcinoma.2015
- Author(s)
  Arai Y, Nakamura H, Totoki Y, Shirota T, Hama N, Ojima H, Hosoda F, Shimada K, Morizane C, Okusaka T, Shibata T.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋市　名古屋国際会議場
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-25290074
[Presentation] 網羅的シークエンス解析による胆管がん分子標的の同定2015
- Author(s)
  新井康仁、中村浩実、十時泰、代田智樹、濱奈津子、尾島英知、細田文恵、島田和明、森実千種、奥坂拓志、柴田龍弘
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26461040
[Presentation] Identification of novel fusion genes in 218 gastric primary cancers by paired-end RNA sequencing.2015
- Author(s)
  Hosoda F, Totoki Y, Rokutan H, Hama N, Arai Y, Taniguchi H, Shibata T.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋市　名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25290074
[Presentation] Identification of aberrant long non-coding RNA transcripts in gastric cancer
- Author(s)
  Hosoda F, Totoki Y, Arai Y, Hama N, Taniguchi H, Shibata T
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25290074
[Presentation] 胆管がんにおける分子標的としてのFGFR2融合遺伝子の同定
- Author(s)
  新井康仁、十時泰、細田文恵、代田智樹、濱奈津子、中村浩実、尾島英知、古田耕、島田和明、小菅智男、森実千種、奥坂拓志、柴田龍弘
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26461040

1. SHIBATA Tatsuhiro (90311414)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. TOTOKI Yasushi (10373333)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. Kato Mamoru (40391916)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Hosoda Fumie (30219191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. TANIGUCHI Hirokazu (30415525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. SUGIURA TSUYOSHI (40322292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 筆宝義隆 (30359632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 高田耕児 (40530621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ROKUTAN Hirofumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. KOJIMA Motohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 尾島英知

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 稲澤譲治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 前田大地

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ARAI Yasuhito 新井 康仁

新井 康仁 アライ ヤスヒト

Research Projects

Research Products

Co-Researchers

Molecular classification of biliary cancer by transcriptome analysis of FFPE specimensPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Decelopment of nect generation precision theraoy for oral cancer by single cell analysis of oral cancer CTCs

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Revealing cancer-cell evolution and intra-tumor heterogeneity by single-cell genome and transcriptome analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Whole transcriptome analysis and novel therapeutic targets in biliary tract cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of novel fusion genes in gastric cancer by whole transcriptome sequencing: Discovery of potential therapeutic targets for gastric cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 医学の歩み-特集がんゲノム研究の進歩-固形がんにおける融合遺伝子の解析と治療への展開2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Molecular detection and clinicopathological characteristics of advanced/recurrent biliary tract carcinomas harboring the FGFR2 rearrangements: a prospective observational study (PRELUDE Study)2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The potential application of PD-1 blockade therapy for early-stage biliary tract cancer.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sarcoma with MGA-NUTM1 fusion in the lung: an emerging entity.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] E74-Like Factor 3 Is a Key Regulator of Epithelial Integrity and Immune Response Genes in Biliary Tract Cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expanding the clinicopathologic and molecular spectrum of BCOR-associated sarcomas in adults.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KMT2A (MLL) fusions in aggressive sarcomas in young adults.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epigenetic landscape influences the liver cancer genome architecture2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epigenetic landscape influences the liver cancer genome architecture.2018

Author(s)

Journal Title

Data Source

[Journal Article] A computational tool to detect DNA alterations tailored to formalin-fixed paraffin-embedded samples in cancer clinical sequencing2018

ARAI Yasuhito 新井康仁

新井康仁アライヤスヒト