KOBAYASHI Sei 小林誠

Researcher Number	80225515
Other IDs
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Affiliation (based on the past Project Information) *help	2021 – 2023: 山口大学, 医学部, 教授(特命) 2017 – 2020: 山口大学, 大学院医学系研究科, 教授 2011 – 2016: 山口大学, 医学(系)研究科(研究院), 教授 2015: 山口大学, 大学院医学研究科, 教授 2014 – 2015: 山口大学, 大学院医学系研究科, 教授 … More 2006 – 2012: 山口大学, 大学院・医学系研究科, 教授 2006: 山口大学, 大学院医学系研究科, 教授 1996 – 2005: 山口大学, 医学部, 教授 2001: Yamaguchi University, School of Medicine, Professor of Physiology, 医学部, 客員助教授 1998: Kyushu University, Faculty of Medicine, Associate Professor, 医学部, 助教授 1991 – 1996: 九州大学, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator General physiology / General physiology / Cerebral neurosurgery / 血管生物学 / Neurophysiology and muscle physiology / Circulatory organs internal medicine / Food science / Cerebral neurosurgery Except Principal Investigator Circulatory organs internal medicine / Basic Section 48020:Physiology-related … More / General physiology / Horticultural science / Applied pharmacology / 神経・脳内生理学 / Food science / Neurophysiology and muscle physiology / Cerebral neurosurgery Less
Keywords	Principal Investigator 血管平滑筋 / スフィンゴ脂質 / Rhoキナーゼ / Rho-kinase / 質量分析 / シグナル伝達 / 血管異常収縮 / 細胞質Ca^<2+>濃度 / Vascular Smooth Muscle / Signal Transduction … More / Vasoactive Substances / Calcium Ion / Smooth Muscle Cells / Blood Vessel / 血管病 / 病態生理 / 機能的プロテオミクス / 血管攣縮 / 細胞内情報伝達 / Ca^<2+>非依存性収縮 / 細胞内情報伝達機構 / 細胞増殖 / 細胞周期 / Vasorelaxation / Vasocontraction / Cell Proliferation / Cell Cycle / 血管 / 膜ラフト / カルシウム非依存性収縮 / 脳血管 / Srcファミリーチロシンキナーゼ / 脳血管攣縮 / エイコサペンタエン酸 / カルシウム / カルシウムイオン / 分子生物学 / 細胞生物学 / 血管平滑筋細胞 / Functional Proteomics / Membrane Raft / Mass Spectrometry / Src family tyrosine kinase / RNA interference / intracellular signal transduction / sphingolipid / calcium-independent contraction / mass spectrometry / abnormal contraction of vascular smooth muscle / 細胞内シグナル伝達 / RNA干渉 / 細胞内カルシウム濃度 / 血管平滑筋の異常収縮 / Ca2 + -independent contraction / Cytosolic Calcium Ion / 細胞質CA^<2+>濃度 / 細胞質Ca^<2+> / Sphingolipids / Ryo-kinase / Endothelial Cells / Cytosolic Celcium Ion / 血管手滑筋 / 血管内皮細胞 / 細胞培養 / 細胞増殖因子 / カルシウムイオンチャネル / 細胞質カルシウムイオン濃度 / 血小板由来増殖因子 / Culcium Ion / Cell Biology / Contraction / Cell Proliferaton / Diabetes Mellitus / 血管作動薬 / 平滑筋細胞 / 収縮 / 糖尿病 / 活性酸素 / 酸化ストレス / 食品機能 / 機能性食品 / 治療薬 / 脳血管障害 / 1分子 / 血管緊張 / スフィンゴシルホスホリルコリン / 細胞賀Ca^<2+>濃度 / 一酸化窒素 / 細胞質カルシウム濃度 / 環状ヌクレオチド / 血管弛緩薬 / チロシンリン酸化 / カルシウムチャネル / 細胞質カルシウム … More Except Principal Investigator 血管平滑筋 / 細胞質カルシウム濃度 / GABA / 血管攣縮 / 内皮依存性弛緩 / NO / 冠動脈 / in situ内皮細胞 / 異常収縮 / vascular smooth muscle / 血管病 / 血管異常収縮 / スフィンゴミエリナーゼ / スフィンゴ脂質 / 内皮細胞 / paxillin / カルパイン / 酸化ストレス / JNK / 血管内皮細胞 / 血管平滑筋細胞 / フラ-2 / muscimol / Fyn / 細胞骨格 / Rhoキナーゼ / 脳血管攣縮 / エンドセリン / 細胞カルシウム濃度 / SPC / tyrosine phosphorylation / abnormal contraction / チロシンリン酸化 / Paxillin / ビメンチン / paxillin ノックアウトマウス / paxillin KO mouse / 血管平滑筋収縮 / 農林水産物 / 植物 / ゲノム / 育種学 / 園芸学 / SNP / コアコレクション / 遺伝資源 / オミクス統合解析 / ニンニク / 生理学 / 機能プロテオミクス / 蛋白質リン酸化反応 / シグナル伝達 / 不可逆的活性 / 受容体脱感作機構 / トロンビン受容体 / 平滑筋細胞 / 活性酸素 / 蛋白質リン酸化 / 細胞内カルシウムシグナル / ミオシン軽鎖リン酸化 / 内皮バリアー機能 / 脱感作障害 / 受容体 / トロンビン / charomatography / kinase / mass spectrometry / protein ourification / seretion / signal transduction / ischemia / heart / 分泌 / カラム / キナーゼ / 質量分析 / 蛋白精製 / 分泌因子 / 細胞外シグナル伝達 / 虚血 / 心臓 / adenovirus / intracellular signaling / oxidative stress / MAP kinase / phenotypic modulation / atherosclerosis / アデノウイルス / 細胞内情報伝達系 / MAPキナーゼ / 形質変換 / 動脈硬化 / glutamate / synaptic potential / optical imaging / superior colliculus / visual system / development / TTX / 活動電位 / in vivo / 光学的記録法 / 電位感受性色素 / 胎仔 / グルタミン酸 / シナプス電位 / 膜電位光学測定 / 上丘 / 視覚系 / 発達 / intracellular signal transduction networks / cell cycle / calcium signaling / intimal thickening / coronary spasm / endothelial cells / 細胞増殖 / 細胞情報伝達 / 冠血管形成術 / 細胞増殖接触抑制 / ミオシン脱燐酸化酵素 / 血管管腔形成 / 細胞情報伝達網 / 細胞周期 / カルシウムシグナリング / 内膜肥厚 / 冠動脈攣縮 / fura-2 / cytosolic calcium concentration / measurements in vivo / vascular smooth muscle cells / Vascular endothelial cells / フラ-ス / 細胞質カルシウム / 生体計測 / 血管内皮 / calcium sensitivity / vasorelaxation / vasoconstriction / cell calcium / 血管〓縮 / cyclic AMP / エンドセリン受容体 / 血管拡張 / カルシウム感受性 / 血管拡張薬 / 血管緊張 / 細胞カルシウム / Endothelium-derived relaxing factor(EDRF) / Endothelin / GTP-binding protein / Ethanol / Myocardial cells / Endothelial cells in situ / Vascular smooth muscle cells / Fura-2 / 細胞膜Ca^<++>濃度 / カプトリル / BCECF / フラー2 / EDRF / G蛋白質 / 内皮由来弛緩因子(EDRF) / GTP結合蛋白質 / エタノール / 心筋細胞 / sympathetic nerve activity / shaker stress / NaCl / borderline hypertensive rat / 脳室内投与 / ビククリン / ムシモ-ル / ストレス / 境界型高血圧 / 食塩 / 交感神経活動 / 高血圧 / 振盪ストレス刺激 / 食塩負荷 / 境界型高血圧ラット / 病的シグナル伝達 / 腫瘍細胞浸潤・転移 / 病的シグナル伝達系 / 細胞運動・遊走 / 細胞骨格関連分子 / ダイナミクス / 分子間相互作用 / 電子顕微鏡 / コレステロール / 食品機能 / ミクロドメイン / プロテオミクス / 平滑筋収縮 / 平滑筋生理 / eNOS / 細胞内情報伝達 / 脳血管 / 内皮由来過分極因子 / 2,3-ジアミノナフタリン法 / 2,3ジアミノナフタレン法 / 百日咳毒素 / G蛋白 Less

Elucidation of the mechanism by which paxillin controls vascular abnormal contraction
- Principal Investigator
  
  ZHANG YING
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
Elucidation of the novel signaling pathway of vimentin-mediated abnormal vascular smooth muscle contraction
- Principal Investigator
  
  Kishi Hiroko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
Elucidation of the mechanism by which paxillin controls vascular abnormal contraction
- Principal Investigator
  
  Zhang Ying
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
Development of core collocation in garlic genetic resources through integrated omics analysis and its evaluation for functionality
- Principal Investigator
  
  SHIGYO MASAYOSHI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Horticultural science
- Research Institution
  Yamaguchi University
Elucidation of the involvement of calpain and cytoskeletal proteins in the signal transduction of abnormal vascular smooth muscle contraction
- Principal Investigator
  
  KISHI Hiroko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Development of innovative and ultimate strategies for the treatment of cerebral vasospams with thrombin receptor as a therapeutic target
- Principal Investigator
  
  Hirano Katsuya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kagawa University
The elucidation of preventive mechanism of vasospasm using food factors via membrane microdomain dynamics
- Principal Investigator
  
  KAJIYA Katsuko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Kagoshima University
Elucidation of the shared signaling pathways for intractable diseases in terms of cytoskeletal rearrangements
- Principal Investigator
  
  KISHI Hiroko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Research for novel signaling molecule involving vascular smooth muscle abnormal contraction
- Principal Investigator
  
  ZHANG Ying
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Identification of food component which selectively inhibits abnormal vascular contractionPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Yamaguchi University
Elucidation of mechanism for production of causal factor of vasospasmPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
The elucidation of the relationship between vascular smooth muscle contraction and cytoskeletal rearrangement by proteomics and functional analysis
- Principal Investigator
  
  KISHI Hiroko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Yamaguchi University
Clarification of molecular mechanisms of abnormal vascular contraction by functional proteomics and a single molecular analysis of signal transductionPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
脳血管攣縮の原因シグナル分子の機能解析とその選択的阻害薬の探索Principal Investigator
- Principal Investigator
  
  小林誠
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamaguchi University
機能的プロテオミクスによる脳血管攣縮の原因分子の網羅的探索と創薬への応用Principal Investigator
- Principal Investigator
  
  小林誠
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamaguchi University
Functional roles of membrane domain and its localized component proteins in abnormal vascular contractionPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Yamaguchi University
脳血管の異常収縮を特異的に阻害する新規の細胞膜脂質分子の同定とシグナル伝達の解明Principal Investigator
- Principal Investigator
  
  小林誠
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamaguchi University
Identification of novel intracellular signaling molecules and clarification of their signal transduction mechanism which regulate abnormal vascular contraction.Principal Investigator
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Identification of activating factors for signal transduction released during ischemia in heart
- Principal Investigator
  
  MIZUKAMI Yoichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Yamaguchi University
脳血管攣縮をひきおこす新しい細胞内シグナル伝達機構の解明
- Principal Investigator
  
  柏木史郎
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamaguchi University
血管の緊張異常を阻害する新規の細胞膜脂質成分の同定と細胞内情報伝達機構の解明Principal Investigator
- Principal Investigator
  
  小林誠
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
新規の生合成経路を有する内皮由来血管弛緩物質の同定および情報伝達機構の解明
- Principal Investigator
  
  最上紀美子
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Molecular mechanism of apoptosis and differentiation in vascular smooth muscle cells: the role of c-Jun N-terminal kinase (JNK)
- Principal Investigator
  
  AOKI Hiroki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
血管の異常収縮を抑制する未知の膜脂質成分の同定および情報伝達機構の解明
- Principal Investigator
  
  最上紀美子
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Molecular and cellular physiological studies on the intracellular signal transduction causing abnormal vascular contractionPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
スフィンゴ脂質情報伝達系による新規の血管機能制御機構に関する分子細胞生理学的研究
- Principal Investigator
  
  最上紀美子
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
スフィンゴ脂質情報伝達系による血管内皮・平滑筋細胞の緊張と細胞周期の調節Principal Investigator
- Principal Investigator
  
  小林誠
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
血管平滑筋細胞の細胞増殖におけるスフィンゴ脂質情報伝達系の役割
- Principal Investigator
  
  MOGAMI Kimiko
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Development of visual input to superior colliculus in fetal rats : in vivo optical imaging.
- Principal Investigator
  
  NAKAMURA Shoji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Yamaguchi University
Development of the method(s) to monitor cardiovascular function and its intracellular signal transductionPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Regulatory mechanisms of cytosolic ion transients during cell cycle progression in vascular endothelial and smooth muscle cellsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
血管弛緩薬による血管の細胞増殖制御に関する細胞分子生物学的研究:特に、環状ヌクレオチド情報伝達系の果たす役割についてPrincipal Investigator
- Principal Investigator
  
  小林誠
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  Kyushu University
Studies on molecular cell biology of the inhibition of coronary vasoconstriction and intimal thickening.
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
細胞周期制御におけるカルシウム情報伝達系の意義:特に血管内皮・平滑筋細胞についてPrincipal Investigator
- Principal Investigator
  
  小林誠
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
TO DEVELOP A NEW SYSTEM TO CONTIMUOUSLY MONITOR THE FUNCTIONS AT THE CELLULAR AND MOLECULAR LEVELS OF THE VASCULAR ENDOTHELIAL AND SMOOTH MUSCLE CELLS IN VIVO.
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
REGULATORY MECHANISMS OF VASCULAR CONTRACTION AND CELL PROLIFERATION IN DIABETES MELLITUSPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  KYUSHU UNIVERSITY
血管機能の調節における内皮および平滑筋細胞情報伝達系の相互作用
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
THE PATHOGENESIS OF AN INCREASE IN VASCULAR TONUS : THE DEVELOPMENT OF NEW VASODILATORS.
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Role of central GABA system in hypertension induced by high salt and stress.
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
THE DEVELOPMENT AND THE CLINICAL APPLICATION OF AN OPTICAL SYSTEM FOR THE SIMULTANEOUS DETERMINATION OF METABOLIC AND FUNCTIONAL CHANGES IN THE HEART AND BLOOD VESSELS.
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY

[Book] Chapter 13, The pivotal role of cholesterol and membrane lipid rafts in the Ca2+-sensitization of vascular smooth muscle contraction leading to vasospasm, Muscle Contraction and Cell Motility: Fundamentals and Developments, edited by Haruo Sugi2016
- Author(s)
  Ying Zhang, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Total Pages
  454
- Publisher
  Pan Stanford
- Data Source
  KAKENHI-PROJECT-16K08496
[Journal Article] Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation2024
- Author(s)
  Zhang Ying、Li Nan、Kobayashi Sei
- Journal Title
  
  Cell Communication and Signaling
  
  Volume: 22 Issue: 1 Pages: 58-58
- DOI
  10.1186/s12964-023-01404-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06782
[Journal Article] Direct active Fyn-paxillin interaction regulates vascular smooth muscle cell migration2023
- Author(s)
  Zhang Ying、Kishi Hiroko、Kobayashi Sei
- Journal Title
  
  Journal of Smooth Muscle Research
  
  Volume: 59 Issue: 0 Pages: 58-66
- DOI
  10.1540/jsmr.59.58
- ISSN
  0916-8737, 1884-8796
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06782
[Journal Article] Fyn-Mediated Paxillin Tyrosine 31 Phosphorylation Regulates Migration and Invasion of Breast Cancer Cells2023
- Author(s)
  Zhang Ying、Zheng Huanyu、Xu Ming、Maeda Noriko、Tsunedomi Ryouichi、Kishi Hiroko、Nagano Hiroaki、Kobayashi Sei
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 21 Pages: 15980-15980
- DOI
  10.3390/ijms242115980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08850, KAKENHI-PROJECT-23K08027, KAKENHI-PROJECT-21K06782
[Journal Article] Inhibitory mechanism of tangeretin, a citrus flavone on the sphingosylphosphorylcholine (SPC)-induced vascular smooth muscle contraction.2022
- Author(s)
  Nan Li, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 149 Issue: 4 Pages: 189-197
- DOI
  10.1016/j.jphs.2022.05.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06782, KAKENHI-PROJECT-20K07261
[Journal Article] Hesperetin Inhibits Sphingosylphosphorylcholine-Induced Vascular Smooth Muscle Contraction by Regulating the Fyn/Rho-Kinase Pathway2022
- Author(s)
  Lu Qian、Kishi Hiroko、Zhang Ying、Morita Tomoka、Kobayashi Sei
- Journal Title
  
  Journal of Cardiovascular Pharmacology
  
  Volume: 79 Issue: 4 Pages: 456-466
- DOI
  10.1097/fjc.0000000000001210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07261, KAKENHI-PROJECT-21K06782
[Journal Article] Paxillin controls actin stress fiber formation and migration of vascular smooth muscle cells by directly binding to the active Fyn2021
- Author(s)
  Zhang Ying、Kishi Hiroko、Morita Tomoka、Kobayashi Sei
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 12
- DOI
  10.1096/fj.202101035rr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07261, KAKENHI-PROJECT-21K06782
[Journal Article] Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn2020
- Author(s)
  Kurahara Lin Hai、Hiraishi Keizo、Yamamura Aya、Zhang Ying、Abe Kohtaro、Yahiro Eiji、Aoki Mikiko、Koga Kaori、Yokomise Hiroyasu、Go Tetsuhiko、Ishikawa Kaori、Bo Zhang、Kishi Hiroko、Kobayashi Sei、Aoki-Shoi Narumi、Toru Satoh、Inoue Ryuji、Hirano Katsuya
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 148 Pages: 50-62
- DOI
  10.1016/j.yjmcc.2020.08.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07309, KAKENHI-PROJECT-20K07061, KAKENHI-PROJECT-20K07092, KAKENHI-PROJECT-20K07261, KAKENHI-PROJECT-20K07269, KAKENHI-PROJECT-17KK0179, KAKENHI-PROJECT-18K06875
[Journal Article] Add-on therapy with traditional Chinese medicine: An efficacious approach for lipid metabolism disorders2018
- Author(s)
  Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Journal Title
  
  Pharmacological Research
  
  Volume: 134 Pages: 200-211
- DOI
  10.1016/j.phrs.2018.06.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06875, KAKENHI-PROJECT-16K08496
[Journal Article] 血管攣縮の分子機構の解明とその分子標的治療法の開発2018
- Author(s)
  張　影、小林　誠
- Journal Title
  
  Precision Medicine
  
  Volume: １ Pages: 71-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06875
[Journal Article] The nutritional characteristics of the hypotensive WASHOKU-modified DASH diet: a sub-analysis of the DASH-JUMP study2018
- Author(s)
  Atsuko Kawamura, Katsuko Kajiya, Hiroko Kishi, Junko Inagaki,　Makoto Mitarai, Hiroshi Oda, Seiji Umemoto, Sei Kobayashi
- Journal Title
  
  Current Hypertension Reviews
  
  Volume: 14 Issue: 1 Pages: 1-10
- DOI
  10.2174/1573402114666180405100430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07795, KAKENHI-PROJECT-15K09123, KAKENHI-PROJECT-16K08496
[Journal Article] Omega-3 and omega-6 DPA equally inhibit the sphingosylphosphorylcholine-induced Ca2+-sensitization of vascular smooth muscle contraction via inhibiting Rho-kinase activation and translocation.2017
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi and Sei Kobayashi
- Journal Title
  
  Scientific Report
  
  Volume: 7 Issue: 1 Pages: 1-14
- DOI
  10.1038/srep36368
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08496, KAKENHI-PROJECT-15K18970
[Journal Article] Effects of the DASH-JUMP dietary intervention in Japanese participants with high-normal blood pressure and stage 1 hypertension: an open-label single-arm trial.2016
- Author(s)
  Kawamura A, Kajiya K, Kishi H, Inagaki J, Mitarai M, Oda H, Umemoto S, Kobayashi S.
- Journal Title
  
  Hypertens Res
  
  Volume: 39 Issue: 11 Pages: 777-785
- DOI
  10.1038/hr.2016.76
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09123, KAKENHI-PROJECT-16K08496
[Journal Article] Effects of the DASH-JUMP dietary intervention in Japanese participants with high-normal blood pressure and stage I hypertension: an open-label single-arm trial2016
- Author(s)
  Atsuko Kawamura, Katsuko Kajiya, Hiroko Kishi, Junko INagaki, Makoto Mitarai, Hiroshi Oda, Seiji Umemoto, Sei Kobayashi
- Journal Title
  
  Hypertension Research
  
  Volume: 0 Pages: 0-0
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25450171
[Journal Article] Fatty acid-binding protein 7 regulates function of caveolae in astrocytes through expression of caveolin-12015
- Author(s)
  Yoshiteru Kagawa, Yuki Yasumoto, Kazem Sharifi, Majid Ebrahimi, Ariful Islam, Hirofumi Miyazaki, Yui Yamamoto, Tomoo Sawada, Hiroko Kishi, Sei Kobayashi, Motoko Maekawa, Takeo Yoshikawa, Eiichi Takaki Akira Nakai, Hiroshi Kogo, Toyoshi Fujimoto, Yuji Owada
- Journal Title
  
  Glia
  
  Volume: 63 Pages: 780-794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659113
[Journal Article] Fatty acid-binding protein 7 regulates function of caveolae in astrocytes through expression of caveolin-12015
- Author(s)
  Yoshiteru Kagawa, Yuki Yasumoto, Kazem Sharifi, Majid Ebrahimi, Ariful Islam, Hirofumi Miyazaki, Yui Yamamoto, Tomoo Sawada, Hiroko Kishi, Sei Kobayashi, Motoko Maekawa, Takeo Yoshikawa, Eiichi Takaki, Akira Nakai, Hiroshi Kogo, Toyoshi Fujimoto, Yuji Owada
- Journal Title
  
  Glia
  
  Volume: 63 Pages: 780-794
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460290
[Journal Article] Fatty acid-binding protein 7 regulates function of caveolae in astrocytes through expression of caveolin-12015
- Author(s)
  Yoshiteru Kagawa, Yuki Yasumoto, Kazem Sharifi, Majid Ebrahimi, Ariful Islam, Hirofumi Miyazaki, Yui Yamamoto, Tomoo Sawada, Hiroko Kishi, Sei Kobayashi, Motoko Maekawa, Takeo Yoshikawa, Eiichi Takaki Akira Nakai, Hiroshi Kogo, Toyoshi Fujimoto, Yuji Owada
- Journal Title
  
  Glia
  
  Volume: 63 Pages: 780-794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380077
[Journal Article] 質量分析計による蛋白質同定～シグナル伝達研究への応用～2015
- Author(s)
  岸博子、張影、小林誠
- Journal Title
  
  山口医学
  
  Volume: 64 Pages: 77-181
- NAID
  130005239550
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460290
[Journal Article] Interaction of peptide-bound beads with lipopolysaccharide and lipoproteins.2014
- Author(s)
  Suzuki,M.M.,Matsumoto,M.,Omi,H.,Kobayashi,T.,Nakamura, A.,Kishi,H.,Kobayashi, S., and Takagi, T.
- Journal Title
  
  J Microbiol Methods.
  
  Volume: 100 Pages: 137-141
- DOI
  10.1016/j.mimet.2014.02.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590295, KAKENHI-PROJECT-25460290
[Journal Article] Phosphorylation of the Kinase Domain Regulates Autophosphorylation of Myosin IIIA and Its Translocation in Microvilli2014
- Author(s)
  Byung Chull An, Tsuyoshi Sakai, Shigeru Komaba, Hiroko Kishi, Sei Kobayashi, Jin Young Kim, Reiko Ikebe, Mistuo Ikebe
- Journal Title
  
  Biochemistry
  
  Volume: 53 Issue: 49 Pages: 7835-7845
- DOI
  10.1021/bi501247z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380077, KAKENHI-PROJECT-23659113, KAKENHI-PROJECT-25460290
[Journal Article] The interaction of Fyn and a cytoskeleton-related protein which is identified as a novel signaling molecule in SPC/Fyn/ROK pathway to mediate abnormal VSM contraction2013
- Author(s)
  Hiroko Kishi, Ying Zhang, Katsuko Kajiya, Tomohiko Kimura, Kenji Miyanari, Sei Kobayashi
- Journal Title
  
  Experimental & Clinical Cardiology
  
  Volume: 18 Pages: 173-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25450171
[Journal Article] Structural and functional analysis of membrane microdomain as a platform for cell signaling pathway of Ca2+-sensitization of vascular smooth muscle contraction2013
- Author(s)
  Katsuko Kajiya, Kazutaka Nojimoto, Hiroko Kishi, Yuichi Takada, Ying Zhang, Sei Kobayashi
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 63 Pages: 116-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25450171
[Journal Article] New avenues to vascular disease prevention by food components2012
- Author(s)
  Katsuko Kajiya, Hiroko Kishi, Yuichi Takada, Ying Zhang, Tomohiko Kimura, Kenji Miyanari, Hiroshi Hagihara, Sei Kobayashi
- Journal Title
  
  Foods & Food Ingredients Journal of Japan
  
  Volume: 217(3) Pages: 284-289
- NAID
  40019419438
- URL
  http://www.ffcr.or.jp/zaidan/FFCRHOME.nsf/pages/ffij-e217(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500364
[Journal Article] Sphingosylphosphorylcholine induces stress fiber formation via activation of Fyn-RhoA-ROCK signaling pathway in fibroblasts2012
- Author(s)
  Dan xu
- Journal Title
  
  Cellular Signaling
  
  Volume: 24 Issue: 1 Pages: 282-289
- DOI
  10.1016/j.cellsig.2011.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J04493, KAKENHI-PROJECT-22500364, KAKENHI-PROJECT-22580131, KAKENHI-PROJECT-23380077, KAKENHI-PROJECT-23659113
[Journal Article] 食品成分による血管病予防の新展開2012
- Author(s)
  加治屋勝子、岸博子、高田雄一、張影、木村友彦、宮成健司、萩原弘、小林誠
- Journal Title
  
  FFIジャーナル
  
  Volume: 217 Pages: 284-289
- NAID
  40019419438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380077
[Journal Article] 食品成分による血管病予防の新展開2012
- Author(s)
  加治屋勝子、岸博子、高田雄一、張影、木村友彦、宮成健司、萩原弘、小林誠
- Journal Title
  
  FFIジャーナル
  
  Volume: 217 Pages: 284-289
- NAID
  40019419438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659113
[Journal Article] Synchronous phosphorylation of CPI-17 and MYPT1 is essential for inducing Ca(2+) sensitization in intestinal smooth muscle2011
- Author(s)
  Mori D, Hori M, Murata T, Ohama T, Kishi H, Kobayashi S, Ozaki H
- Journal Title
  
  Neurogastroenterol Motil
  
  Volume: 23(12) Issue: 12 Pages: 1111-1122
- DOI
  10.1111/j.1365-2982.2011.01799.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228005, KAKENHI-PROJECT-21380178, KAKENHI-PROJECT-22500364, KAKENHI-PROJECT-22658089
[Journal Article] Focused proteomic approach to identify novel signaling molecules for abnormal vascular smooth muscle contraction2010
- Author(s)
  Hiroko Kishi, Shoko Nakajima, Hozumi Kawamichi, Katsuko Kajiya, Yuichi Takada, Daisuke Tokumori, Sei Kobayashi
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 60(Supplement 1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500364
[Journal Article] Focused Proteomicsによる、血管平滑筋異常収縮の新規病的シグナル分子の探索2010
- Author(s)
  岸博子、中島彰子、川道穂津美、加治屋勝子、王晨、高田雄一、小林誠
- Journal Title
  
  日本平滑筋学会雑誌
  
  Volume: 14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500364
[Journal Article] Nifedipine activates PPARand exerts an antioxidative action through Cu/ZnSOD independent of blood-pressure lowering in SHRSP2010
- Author(s)
  Ryo Hashimoto, Seiji Umemoto、Fengling Guo, Kyoko Umeji, Shinichi Itoh, Hiroko Kishi, Sei Kobayashi, and Masunori Matsuzaki
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 17(8) Pages: 785-795
- URL
  https://www.jstage.jst.go.jp/browse/jat/17/8/_contents
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500364
[Journal Article] Elevated concentrations of sphingosylphosphorylcholine in cerebrospinal fluid after subarachnoid hemorrhage : A possible role as a spasmogen.2009
- Author(s)
  T.Kurokawa, Y.Yumiya, H.Fujisawa, S.Shirao, S.Kashiwagi, M.Sato, H.Kishi, S.Miwa, K.Mogami, S.Kato, T.Akimura, M.Soma, K.Ogasawara, A.Ogawa, S.Kobayashi, M.Suzuki
- Journal Title
  
  J Clin Nuerosci 16
  
  Pages: 1064-1068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390059
[Journal Article] Involvement of Fyn tyrosine kinase in actin stress fiber formation in fibroblasts2007
- Author(s)
  Xu, D., Kishi, H., Kawamichi, H., Kajiya, K., Takada, Y., Kobayashi, S
- Journal Title
  
  FEBS Lett 581(peer-reviewed)
  
  Pages: 5227-5233
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] Cholesterol primes vascular smooth muscle to induce Ca^<2+> sensitization mediated by a sphingosylphosphorylcholine-Rho-kinase pathway : possible role for membrane raft2006
- Author(s)
  Morikage, N., Kishi, H., Sato, M., Guo, F., Shirao, S., Yano, T., Soma, M., Hamano, K., Esato, K., Kobayashi, S
- Journal Title
  
  Circ Res 99(peer-reviewed)
  
  Pages: 299-306
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] Sphingomyelinase causes endothelium-dependent vasorelaxation through endothelial nitric oxide production without cytosolic Ca^<1+> elevation2005
- Author(s)
  Mogami, K., Kishi, H., Kobayashi, S
- Journal Title
  
  FEBS Lett 579(peer-reviewed)
  
  Pages: 393-397
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300128
[Patent] 安息香酸誘導体を含む血管攣縮抑制剤、食品及び食品添加剤2017
- Inventor(s)
  小林　誠、岸　博子、高松日出子、石川敦子
- Industrial Property Rights Holder
  山口大学、株式会社タカマ
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-237056
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K08496
[Patent] SPC/Fyn/Rhoキナーゼシグナル伝達経路の阻害剤2015
- Inventor(s)
  岸博子、張影、小林誠
- Industrial Property Rights Holder
  山口大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-05-07
- Data Source
  KAKENHI-PROJECT-25460290
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  高松日出子、小林誠、宮成健司、岸　博子、他3名
- Industrial Property Rights Holder
  株式会社タカマ
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-25460290
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林　誠、高柿了大、岸　博子、張影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  国立大学法人山口大学、株式会社ラフィーネインターナショナル
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-23380077
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林誠、高柿了大、岸博子、張影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  山口大学、株式会社ラフィ‐ネインタ‐ナショナル
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-210258
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-25893150
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林　誠、高柿了大、岸　博子、張　影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  国立大学法人山口大学、株式会社ラフィーネインターナショナル
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-25460290
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林　誠、高柿了大、岸　博子、張影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  国立大学法人山口大学、株式会社ラフィーネインターナショナル
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-23659113
[Patent] 血管弛緩作用を有するペプチド及び血管弛緩剤2013
- Inventor(s)
  小林誠、木村友彦、岸博子、加治屋勝子、高田雄一、白土絵理
- Industrial Property Rights Holder
  小林誠、木村友彦、岸博子、加治屋勝子、高田雄一、白土絵理
- Industrial Property Rights Type
  特許
- Filing Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-25450171
[Patent] 血管弛緩作用を有するペプチド及び血管弛緩剤2013
- Inventor(s)
  小林誠、木村友彦、岸博子、加治屋勝子、高田雄一、白土絵里
- Industrial Property Rights Holder
  山口大学、林兼産業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-23659113
[Patent] 血管弛緩作用を有するペプチドおよび血管弛緩剤2013
- Inventor(s)
  小林　誠、木村友彦、岸　博子、加治屋勝子、高田雄一、白土絵里
- Industrial Property Rights Holder
  国立大学法人山口大学、林兼産業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-25460290
[Patent] 血管病予防に効果を有する食品組成物2013
- Inventor(s)
  小林誠、岸博子
- Industrial Property Rights Holder
  国立大学法人山口大学
- Acquisition Date
  2013-02-01
- Data Source
  KAKENHI-PROJECT-22500364
[Patent] 平滑筋収縮抑制剤2012
- Inventor(s)
  小林誠、岸博子、横地俊弘、中原東郎
- Industrial Property Rights Holder
  国立大学法人山口大学
- Acquisition Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-22500364
[Patent] 血管異常収縮の抑制剤2012
- Inventor(s)
  小林誠、岸博子、中島幹夫、前田祥範
- Industrial Property Rights Holder
  国立大学法人山口大学、国立大学法人佐賀大学
- Acquisition Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-22500364
[Patent] 平滑筋収縮抑制剤2012
- Inventor(s)
  扇谷悟、森田直樹、花田啓子、小林利克、小林誠、岸博子、宮下和夫、細川雅史
- Industrial Property Rights Holder
  国立大学法人山口大学
- Acquisition Date
  2012-12-21
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] 血管平滑筋異常収縮のシグナル伝達におけるカルパイン活性化および中間径フィラメントビメンチン断片化の役割の解明2022
- Author(s)
  岸博子、路倩、森田知佳、張影、李楠、小林誠
- Organizer
  第64回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] 血管平滑筋異常収縮のシグナル伝達における中間径フィラメントビメンチン断片化の役割の解明2022
- Author(s)
  岸博子、路倩、森田知佳、張影、李楠、小林誠
- Organizer
  第６４回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] Paxillinは活性型Fynに直接結合することにより血管平滑筋細胞のストレスファイバー形成と細胞遊走を制御する2022
- Author(s)
  張影、森田知佳、小林誠、岸博子、宮本達雄
- Organizer
  第６４回日本平滑筋学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] The role of vimentin cleavage and calpain in the Ca2+-sensitization of vascular smooth muscle contraction2022
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Nan Li, Sei Kobayashi
- Organizer
  第99回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Paxillin は活性型Fyn に直接結合することにより血管平滑筋細胞のストレスファイバー形成と細胞遊走を制御する2022
- Author(s)
  張影、森田知佳、小林誠、岸博子、宮本達雄
- Organizer
  第64回日本平滑筋学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Madagascine induces vasodilatation via AMPK-mediated eNOS activation and ROCK inhibition2021
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] 血管平滑筋異常収縮のシグナル伝達におけるカルパインの役割の解明2021
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、李楠、小林誠
- Organizer
  第63回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Madagascine induces vasodilatation via AMPK-mediated eNOS activation and ROCK inhibition2021
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Paxillin is a novel signaling molecule which regulates abnormal vascular contraction mediated by an SPC/Fyn/Rho-kinase pathway2021
- Author(s)
  Ying Zhang, Tomoka Morita, Bochao Lyu, Dan Cui, Hiroko Kishi, Min Zhang, Qian Lu, Nan Li, Eiji Ikeda, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Fyn KOマウスの脳底動脈と前腸間膜動脈のスフィンゴシルホスホリルコリンに対する反応性について2021
- Author(s)
  森田知佳、張影、岸博子、小林誠
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] Compound B from traditional Chinese medicine inhibits the Rho-kinase (ROK)-mediated Ca2+-sensitization of vascular smooth muscle contraction induced by a spasmogen, sphingosylphosphorylcholine (SPC)2021
- Author(s)
  Minhui Xu, Min Zhang, Bochao Lyu, Qian Lu, Nan Li, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Sphingosylphosphorylcholine induced contraction in basilar arteries of Fyn knockout mice2021
- Author(s)
  Tomoka Morita, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 異常収縮刺激時Fynの活性化によるpaxillinのチロシンリン酸化について2021
- Author(s)
  張　影、呂　博超、森田　知佳、岸　博子、路　倩、李　楠、小林　誠
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] 血管平滑筋異常収縮のシグナル伝達におけるカルパインの役割の解明2021
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、李楠、小林誠
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] The role of calpain activation and vimentin cleavage in Ca2+-sensitization of vascular smooth muscle contraction2021
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Molecular mechanism of component T inhibiting abnormal vascular contraction and migration of MDA-MB-231 cancer cells2021
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The role of calpain activation and vimentin cleavage in Ca2+-sensitization of vascular smooth muscle contraction2021
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Compound B from traditional Chinese medicine inhibits the Rho-kinase (ROK)-mediated Ca2+-sensitization of vascular smooth muscle contraction induced by a spasmogen, sphingosylphosphorylcholine (SPC)2021
- Author(s)
  Minhui Xu, Min Zhang, Bochao Lyu, Qian lu, Nan li, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The inhibitory effect and mechanism exploration of compound H on sphingosylphosphorylcholine (SPC)-induced contraction in vascular smooth muscle2021
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Tomoka Morita, Hiroko Kishi, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The inhibitory effect and mechanism exploration of compound H on sphingosylphosphorylcholine (SPC)-induced contraction in vascular smooth muscle2021
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Tomoka Morita, Hiroko Kishi, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Molecular mechanism of component T inhibiting abnormal vascular contraction and migration of MDA-MB-231 cancer cells2021
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Deletion of Paxillin Attenuates Sphingosylphosphorylcholine (SPC)-Induced Abnormal Contraction of Vascular Smooth Muscle by Inhibiting Rho-kinase Activity2021
- Author(s)
  Ying Zhang, Tomoka Morita, Bochao Lyu, Dan Cui, Hiroko Kishi, Min Zhang, Qian Lu, Nan Li, Eiji Ikeda, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Sphingosylphosphorylcholine induced contraction in basilar arteries of Fyn knockout mice.2021
- Author(s)
  Tomoka Morita, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Specific inhibitory effects of compound T, upon pre- or post-treated, on the sphingosylphosphorylcholine (SPC)-induced Ca2+-sensitization of vascular smooth muscle contraction through suppressing the Fyn/Rho-kinase signaling pathway, without affecting Ca2+-dependent contraction2021
- Author(s)
  Nan Li, Ying Zhang, Hiroko Kishi, Tomoka Morita, Bochao Lyu, Sei Kobayashi.
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおけるカルパインの活性化とビメンチン断片化の役割の解明2020
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、張敏、李楠、徐敏慧、小林誠
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Madagascine induces vasodilatation via activation of AMPK2020
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおけるカルパインの活性化とビメンチン断片化の役割の解明2020
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、張敏、李楠、徐敏慧、小林誠
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] The inhibitory mechanism of T on MDA-MB-231 breast cancer cell migration and the mechanism of inhibiting the SPC-induced abnormal contraction.2020
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Novel signaling molecules which can regulate both Ca2+-sensitization of vascular contraction and cancer cell migration2020
- Author(s)
  Sei Kobayashi, Bochao Lyu, Min Zhang, Ying Zhang, Hiroko Kishi, Tomoka Morita
- Organizer
  第97回日本生理学会　3月17日～19日　誌上開催
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Madagascine induces vasodilatation via activation of AMPK2020
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Compound H inhibits sphingosylphosphorylcholine（SPC）-induced contraction via suppressing Fyn/Rho-kinase pathway in vascular smooth muscle2020
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Compound H inhibits sphingosylphosphorylcholine-induced contraction via suppressing Fyn/Rho-kinase pathway in vascular smooth muscle2020
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] スフィンゴシルホスホリルコリン（SPC）による血管平滑筋のCa2+感受性収縮におけるパキシリンの役割2020
- Author(s)
  張影、呂博超、森田知佳、崔丹、岸博子、張敏、路倩、李楠、池田栄二、小林誠
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The role of calpain activation and vimentin cleavage in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway2020
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第97回日本生理学会　3月17日～19日　誌上開催
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] The inhibitory mechanism of T on MDA-MB-231 breast cancer cell migration and the SPC-induced abnormal contraction leading to vasospasm2020
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Role of paxillin in sphingosylphosphorylcholine (SPC)-induced Ca2+-sensitization contraction of vascular smooth muscle2020
- Author(s)
  Ying Zhang, Bochao Lyu, Tomoka Morita, Dan Cui, Hiroko Kishi, Min Zhang, Qian Lu, Nan Li, Eiji Ikeda, Sei Kobayashi
- Organizer
  第97回日本生理学会　3月17日～19日　誌上開催
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] スフィンゴシルホスホリルコリン（SPC）による血管平滑筋のCa2+感受性収縮におけるパキシリンの役割2020
- Author(s)
  張影、呂博超、森田知佳、崔丹、岸博子、張敏、路倩、李楠、池田栄二、小林誠
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管平滑筋異常収縮における新規分子パキシリンの関与について2019
- Author(s)
  張　影、呂　博超、森田　知佳、崔　丹、岸　博子、張　敏、路　倩、李　楠、池田　栄二、小林　誠
- Organizer
  2019年11月23～24日、第71回日本生理学会中国四国地方会、山口大学小串キャンパス（医学部）総合研究棟Ａ（医修館）
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管平滑筋収縮のCa2+-sensitizationおよびCa2+依存性収縮におけるカルパインの関与2019
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、張敏、李楠、小林誠
- Organizer
  2019年8月1 ～3日、第61回日本平滑筋学会総会、名古屋大学　野依記念学術交流館
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Direct Fyn-paxillin binding controls migration of coronary artery smooth muscle cells2019
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita, Qian Lu, Nan Li, Sei Kobayashi
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies (FAOPS) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The involvement of calpain in abnormal vascular smooth muscle contraction induced by SPC and U466192019
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Sei Kobayashi
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies (FAOPS) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] 食用成分から、血管攣縮を抑制する水溶性物質を発見する。2019
- Author(s)
  豊川絢子、呂博超、張敏、張影、小林誠
- Organizer
  2019年11月23～24日、第71回日本生理学会中国四国地方会、山口大学小串キャンパス（医学部）総合研究棟Ａ（医修館）
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管の異常収縮に対するニンニクの新規機能の発見2019
- Author(s)
  小林誠・呂博超・張敏・路倩・李楠・平田翔・執行正義・張影・岸博子・森田知佳
- Organizer
  園芸学会令和元年度秋季大会テーマセッション「オミクス統合解析によるニンニク遺伝資源・コアコレクションの構築とその機能性評価」
- Data Source
  KAKENHI-PROJECT-17H03766
[Presentation] The involvement of calpain in abnormal vascular smooth muscle contraction induced by SPC and U466192019
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Sei Kobayashi
- Organizer
  2019年3月28 - 30日、第9回FAOPS大会　神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] オミクス統合解析によるニンニク遺伝資源・コアコレクションの構築とその機能性評価2019
- Author(s)
  執行正義・平田翔・山田朋宏・佐藤修正・澤田有司・數村公子・小林誠
- Organizer
  園芸学会令和元年度秋季大会テーマセッション「オミクス統合解析によるニンニク遺伝資源・コアコレクションの構築とその機能性評価」
- Data Source
  KAKENHI-PROJECT-17H03766
[Presentation] パキシリンは血管攣縮を制御する新規シグナル分子である2019
- Author(s)
  張　影、呂　博超、森田　知佳、崔　丹、岸　博子、張　敏、路　倩、李　楠、池田　栄二、小林　誠
- Organizer
  2019年8月1～3日、第61回日本平滑筋学会総会、名古屋大学　野依記念学術交流館
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Direct Fyn-paxillin binding controls migration of coronary artery smooth muscle cells.2019
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita, Qian Lu, Nan Li, Sei Kobayashi
- Organizer
  2019年3月28 - 30日、第9回FAOPS大会　神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 肺動脈性肺高血圧症に対するエイコサペンタエン酸の改善効果2019
- Author(s)
  倉原琳、平石敬三、張影、山村彩、岸博子、小林誠、井上隆司、平野勝也
- Organizer
  2019年11月23～24日、第71回日本生理学会中国四国地方会、山口大学小串キャンパス（医学部）総合研究棟Ａ（医修館）
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管攣縮と癌細胞遊走の両方を阻止できる新規の水溶性食品成分の発見2018
- Author(s)
  浅田充夫、呂博超、張敏、張影、岸博子、森田知佳、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] エイコサペンタエン酸（EPA）による肺動脈高血圧病態の改善効果2018
- Author(s)
  倉原琳、平石敬三、張影、山村彩、岸博子、小林誠、井上隆司
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Compound A suppresses the Fyn/Rho-kinase mediated Ca2+-sensitization of vascular smooth muscle contraction2018
- Author(s)
  Bochao Lyu, Min Zhang, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] The involvement of membrane rafts in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway: Part II2018
- Author(s)
  Hiroko Kishi, Miki Kajima, Katsuko Kajiya, Ying Zhang, Tomoka Morita, Bochao Lyu, Min Zhang, Sei Kobayashi
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] ドコサペンタエン酸 (DPA)は、n-3とn-6の両系統とも同じ力価で、Rhoキナーゼの細胞内移動と活性化を抑制する事によって血管異常収縮を抑制する2018
- Author(s)
  張影、張　敏、呂　博超、岸博子、森田知佳、路　倩、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Fyn-mediated tyrosine phosphorylation of a novel signaling molecule, paxillin controls stress fiber formation and migration of cancer cells2018
- Author(s)
  Shiori Yokobayashi, Ying Zhang, Takafumi Okamoto, Tomoka Morita, Hiroko Kishi, Takeshi Yamamoto, Sei Kobayashi
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The novel compound from soybean strongly and selectively inhibits the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2018
- Author(s)
  張敏、張影、呂博超、高柿了大、岸博子、加治屋勝子、森田知佳、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] 活性型FynチロシンキナーゼのパキシリンN末端への直接結合は血管平滑筋細胞のストレスファイバー形成と細胞遊走を制御する2018
- Author(s)
  張影、岸博子、呂　博超、張　敏、森田知佳、路　倩、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 活性型FynチロシンキナーゼのパキシリンN末端への直接結合は血管平滑筋細胞のストレスファイバー形成と細胞遊走を制御する2018
- Author(s)
  張影、岸博子、呂博超、張敏、森田知佳、路倩、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおける、カルパインの役割2018
- Author(s)
  岸博子、張影、森田知佳、呂博超、張敏、路倩、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管平滑筋のCa2+非依存性収縮と細胞遊走を制御する新規シグナル分子の同定2018
- Author(s)
  張影、松永一真、岡本嵩史、呂博超、張敏、森田知佳、岸博子、小林誠
- Organizer
  筋生理の集い
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Compound A suppresses the Fyn/Rho-kinase mediated Ca2+-sensitization of vascular smooth muscle contraction2018
- Author(s)
  呂博超、張敏、張影、岸博子、森田知佳、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The novel compound from soybean strongly and selectively inhibits the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction.2018
- Author(s)
  Min Zhang, Ying Zhang, Bochao Lyu, Ryodai Takagaki, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] エイコサペンタエン酸（EPA）による肺動脈高血圧病態の改善効果2018
- Author(s)
  倉原　琳、平石　敬三、張　影、山村　彩、岸　博子、小林　誠、井上　隆司
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Omega-3 and omega-6 docosapentaenoic acid (DPA) equally inhibit the Ca2+-sensitization of abnormal vascular contractions via inhibiting the Rho-kinase activation and translocation.2018
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita, and Sei Kobayashi
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] ドコサペンタ塩酸(DPA)は、n-3とn-6の両系統とも同じ力価で、Rhoキナーゼの細胞内移動と活性化を抑制する事によって血管異常収縮を抑制する2018
- Author(s)
  張影、張敏、呂博超、岸博子、森田知佳、路倩、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Discovery of novel compound from soybean which selectively inhibits the normal vascular contraction leading to vasospasm2018
- Author(s)
  Min Zhang, Ying Zhang, Bochao Lyu, Ryodai Takagaki, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Organizer
  2018年10月27 - 28日、第70回日本生理学会中国四国地方会、愛媛大学医学部　創立40周年記念講堂　(松山)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおける、カルパインの役割2018
- Author(s)
  岸博子、張影、森田知佳、呂博超、張敏、路倩、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] 血管攣縮と癌細胞遊走の両方を阻止できる新規の水溶性食品成分の発見2018
- Author(s)
  浅田　充夫、呂博超、張敏、張影、岸博子、森田知佳、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Tyrosine phosphorylation of paxillin regulates migration and invasion of cancer cells2017
- Author(s)
  Takafumi Okamoto, Ying Zhang, Kazumasa Matsunaga, Shiori Yokobayashi, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松 (浜松)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Paxillin as a novel signaling molecule regulates actin stress fiber formation and migration of vascular smooth muscle cells by its N-terminus binding to active Fyn2017
- Author(s)
  Ying Zhang, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松 (浜松)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] パキシリンはN末端と活性型Fynとの相互作用により血管平滑筋細胞遊走を制御する2017
- Author(s)
  張影、岸博子、森田知佳、呂博超、張敏、横林志織、小林誠
- Organizer
  第59回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The novel compound from soybean strongly and selectively inhibits the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2017
- Author(s)
  張敏、張影、呂博超、岸博子、加治屋勝子、森田知佳、小林誠
- Organizer
  第59回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The involvement of membrane rafts in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway2017
- Author(s)
  Hiroko Kishi, Ying Zhang, Katsuko Kajiya, Tomoka Morita, Bochao Lyu, Min Zhang, Xiaoyan Li, Sei Kobayashi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松 (浜松)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] スフィンゴシルホスホリルコリンが誘発する血管平滑筋異常収縮シグナル分子の細胞内局在の変化の検討2017
- Author(s)
  岸博子、張影、加治屋勝子、森田知佳、呂博超、張敏、小林誠
- Organizer
  第59回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The novel compound from soybean has a strong inhibitory effect on the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2016
- Author(s)
  張敏、張影、呂博超、岸博子、森田知佳、小林誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京慈恵会医科大学 (東京)
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Flippase mediates the transmembranous transport of sphingosylphosphorylcholine, a spasmogen of human coronary and cerebral arteries2016
- Author(s)
  Shoko Iwanaga, Hiroko Kishi, Sei Kobayashi
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター (札幌)
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Compound X inhibits the ROK-mediated Ca2+-sensitization of vascular smooth muscle contraction induced by a spasmogen, sphingosylphosphorylcholine2016
- Author(s)
  Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第68回日本生理学会中国四国地方会
- Place of Presentation
  岡山大学Junko Fukutakeホール (岡山)
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The MLC20 monophosphorylation-dependent and -independent Ca2+-sensitization, respectively at the early and late phase of vascular smooth muscle abnormal contraction2016
- Author(s)
  Hiroko Kishi, Ying Zhang, Tomoka Morita, Bochao Lyu, Min Zhang, Sei Kobayashi
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター (札幌)
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管平滑筋異常収縮を特異的に抑制する食用植物由来成分の探索2015
- Author(s)
  吉井大智、張　影、岸　博子、小林　誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟 (宇部)
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] SPC/Fyn/ROK経路による血管平滑筋収縮Ca2+感受性亢進のシグナル伝達における、ミオシン軽鎖リン酸化の検討2015
- Author(s)
  岸　博子、張　影、呂　博超、張　敏、小林　誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟 (宇部)
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] WASHOKU-modified DASH diet reduces blood pressure and improves cardiovascular risk factors independently of body weight in subjects with untreated high blood pressure and stage 1 hypertension2015
- Author(s)
  A. Kawamura, S. Umemoto, J. Inagaki, H. Kishi, K. Kajiya, M. Mitarai, H. Oda, S. Kobayashi
- Organizer
  ESC Congress 2015
- Place of Presentation
  London (United Kingdom)
- Year and Date
  2015-08-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] Effects of the WASHOKU-modified DASH diet on blood pressure and cardiovascular risk factors among subjects with high normal blood pressure and stage 1 hypertension2015
- Author(s)
  Katsuko Kajiya, Atsuko Kawamura, Hiroko Kishi, Makoto Mitarai, Hiroshi Oda, Seiji Umemoto, Sei Kobayashi
- Organizer
  The 6th International Conference on Food Factor
- Place of Presentation
  Seoul (Korea)
- Year and Date
  2015-11-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] 活性化FynとパキシリンN末端との相互作用は血管平滑筋細胞のストレスファイバー形成と細胞遊走において重要な役割を担う2015
- Author(s)
  張　影、岸　博子、加治屋勝子、呂　博超、張　敏、森田　智佳、小林　誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟 (宇部)
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Docosapentaenoic acid (DPA) n-6 不飽和脂肪酸により新たな血管攣縮の抑制作用の発見とその分子機構の解明2015
- Author(s)
  張　影、張　敏、呂　博超、岸　博子、小林　誠
- Organizer
  第67回日本生理学会中国四国地方会
- Place of Presentation
  米子コンベンションセンター小ホール (米子)
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Effects of the Washoku-modified DASH diet on blood pressure and cardiometabolic risk factors in subjects with untreated high normal blood pressure and stage 1 hypertension2015
- Author(s)
  S. Umemoto, A. Kawamura, J. Inagaki, H. Kishi, K. Kajiya, M. Mitarai, K. Oda, S. Kobayashi
- Organizer
  25th European Meeting on Hypertension and Cardiovascular Protection
- Place of Presentation
  Milan(Italy)
- Year and Date
  2015-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] 血管平滑筋収縮のカルシウム感受性亢進における、タンパク質分解酵素の関与の可能性2014
- Author(s)
  岸　博子、張　影、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京慈恵会医科大学 (東京都)
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The time course of Fyn and ROK activation in the signal transduction of abnormal vascular smooth muscle contraction2014
- Author(s)
  Hiroko Kishi, Ying Zhang, Ryodai Takagaki, Kenji Miyanari, Tomohiko Kimura, Sei Kobayashi
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス(鹿児島)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The role of direct phosphorylation of myosin light chain by Rho-kinase in Ca2+-sensitization of smooth muscle contraction2014
- Author(s)
  Sei Kobayashi
- Organizer
  第91回日本生理学会
- Place of Presentation
  鹿児島大学（鹿児島県）
- Invited
- Data Source
  KAKENHI-PROJECT-23659113
[Presentation] Important role of cell membrane microdomain for Ca2+-sensitization of vascular smooth muscle contraction2014
- Author(s)
  Katsuko Kajiya, Kazutaka Nojimoto, Hiroko Kishi, Yuichi Takada, Ying Zhang, Sei Kobayashi
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス(鹿児島)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管平滑筋アクチン・ストレスファイバーの形成を担う新規シグナル分子の同定とその機能解析2013
- Author(s)
  張　影、岸　博子、加治屋勝子、宮成健司、木村友彦、小林　誠
- Organizer
  第55回日本平滑筋学会総会
- Place of Presentation
  旭川市大雪クリスタルホール(旭川)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The interaction of Fyn and a cytoskeleton-related protein which is identified as a novel signaling molecule in SPC/Fyn/ROK pathway to mediate abnormal VSM contraction2013
- Author(s)
  Hiroko Kishi, Ying Zhang, Katsuko Kajiya, Tomohiko Kimura, Kenji Miyanari, Sei Kobayashi
- Organizer
  第36回心筋代謝研究会
- Place of Presentation
  キヤノンマーケティングジャパン株式会社 3階ホール(東京)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管異常収縮の新規シグナル分子として同定された細胞骨格関連分子の、Fynとの相互作用解析2013
- Author(s)
  岸　博子、張　影、加治屋勝子、高田雄一、宮成健司、木村友彦、野地本和孝、小林　誠
- Organizer
  第55回日本平滑筋学会総会
- Place of Presentation
  旭川市大雪クリスタルホール(旭川)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 冠血管弛緩作用を有する新規ペプチドの探索: 続報2013
- Author(s)
  木村友彦、宮成健司、高柿了大、張影、岸博子、小林誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京慈恵会医科大学(東京)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管平滑筋異常収縮の病的シグナル伝達における細胞膜上マイクロドメインの新規機能2013
- Author(s)
  加治屋勝子、野地本和孝、岸　博子、張　影、高田雄一、木村友彦、宮成健司、小林　誠
- Organizer
  第55回日本平滑筋学会総会
- Place of Presentation
  旭川市大雪クリスタルホール(旭川)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Important role of lipid mediators in molecular mechanisms of abnormal vascular contraction2012
- Author(s)
  S.Kobayashi
- Organizer
  第89回日本生理学会
- Place of Presentation
  長野県松本文化会館(松本)(招待講演)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23380077
[Presentation] Important role of lipid mediators in molecular mechanisms of abnormal vascular contraction2012
- Author(s)
  S. Kobayashi
- Organizer
  第89回日本生理学会(招待講演)
- Place of Presentation
  長野県松本文化会館（松本）
- Data Source
  KAKENHI-PROJECT-23659113
[Presentation] Essential roles of Fyn tyrosine kinase and membrane lipid raft in smooth muscle contraction2009
- Author(s)
  小林誠
- Organizer
  International Symposium Post-genomic advances in the physiology of smooth muscle
- Place of Presentation
  名古屋市立大学
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20390059
[Presentation] Essential roles of Fyn tyrosine kinase and membrane lipid raft in Ca2+-sensitization of vascular smooth mudcle contraction.2009
- Author(s)
  Kobayashi S
- Organizer
  International Symposium Post-genomic Advances in the Physiology of Smooth Muscle
- Place of Presentation
  名古屋市立大学
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20390059
[Presentation] Essential roles of Fyn tyrosine kinase and membrane lipid raft in Ca2+-sensitization of vascular smooth mudcle contraction.2009
- Author(s)
  Kobayashi S
- Organizer
  International Symposium Post-genomic Advances in the Physiology of Smooth Muscle
- Place of Presentation
  名古屋市立大学
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20659222
[Presentation] 血管平滑筋収縮のCa^<2+>感受性増強におけるFynチロシンキナーゼの重要性2008
- Author(s)
  小林誠
- Organizer
  適応医学会第12回学術集会
- Place of Presentation
  ビーコンプラザ、別府
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20659222
[Presentation] 血管平滑筋収縮のCa感受性増強におけるFynチロシンキナーゼの重要性2008
- Author(s)
  小林誠
- Organizer
  適応医学会
- Place of Presentation
  別府ビーコンプラザ
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20390059
[Presentation] 血管平滑筋収縮のCa^<2+>感受性増強におけるFynチロシンキナーゼ. の重要性2008
- Author(s)
  小林誠
- Organizer
  適応医学会第12回学術集会
- Place of Presentation
  ビーコンプラザ、別府
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20390059
[Presentation] 平滑筋収縮のカルシウム感受性増強の分子機構2007
- Author(s)
  小林誠
- Organizer
  第49回日本平滑筋学会
- Place of Presentation
  橿原ロイヤルホテル(奈良県)
- Year and Date
  2007-07-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300128
[Presentation] SPC/Fyn/ROK経路による血管平滑筋収縮Ca2+感受性亢進のシグナル伝達における、FynおよびROK活性化の経時的変化の検討
- Author(s)
  岸　博子、張　影、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+-sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] パキシリンのN末端は活性型Fynチロシンキナーゼとの結合によりストレスファイバー形成を制御する
- Author(s)
  張影、岸博子、宮成健司、木村友彦、高柿了大、加治屋勝子、小林誠
- Organizer
  第120回日本解剖学会・第92回日本生理学会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県、神戸市）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] 正常高値血圧及びⅠ度高血圧者のための日本人向けDASH食事療法「DASH-JUMP」の食生活における行動変容への影響
- Author(s)
  河村敦子、稲垣順子、加治屋勝子、岸博子、梅本誠治、御手洗誠、織田浩司、小林誠
- Organizer
  第37回日本高血圧学会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23659113
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張影、岸博子、宮成健司、木村友彦、高柿了大、呂博超、小林誠
- Organizer
  第５６回日本平滑筋学会
- Place of Presentation
  新横浜プリンスホテル（横浜市）
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] Novel fish-derived peptide fragments which induce endothelium-dependent and -independent vasorelaxation
- Author(s)
  Tomohiko Kimura, Yuichi Takada, Katsuko Kajiya, Ying Zhang, Kenji Miyanari, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The novel role of calpain in SPC/Fyn/ROK pathway which mediates the signal transduction of abnormal vascular smooth muscle contraction
- Author(s)
  Hiroko Kishi, Ying Zhang, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張　影、岸　博子、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-23659113
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張　影、岸　博子、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-23380077
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+- sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23659113
[Presentation] 血管平滑筋におけるRhoキナーゼを介在したカルシウム感受性亢進を特異的に阻害する新規のサラシア由来成分の探索
- Author(s)
  宮成健司、野地本和孝、加治屋勝子、高田雄一、木村友彦、張影、岸博子、小林誠
- Organizer
  第120回日本解剖学会・第92回日本生理学会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県、神戸市）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] FABP7 is involved in epigenetic modification of mouse caveolin-1 gene promotor
- Author(s)
  Yoshiteru Kagawa, Hiroshi Kogo, Hiroko Kishi, Sei Kobayashi, Toyoshi Fujimoto
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Novel fish-derived peptide fragments which induce endothelium-dependent and -independent vasorelaxation
- Author(s)
  Tomohiko Kimura, Yuichi Takada, Katsuko Kajiya, Ying Zhang, Kenji Miyanari, Hiroko Kishi, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+-sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Katsuko Kajiya, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張　影、岸　博子、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] SPC/Fyn/ROK経路による血管平滑筋収縮Ca2+感受性亢進のシグナル伝達における、FynおよびROK活性化の経時的変化の検討
- Author(s)
  岸博子、張影、宮成健司、木村友彦、高柿了大、呂博超、小林誠
- Organizer
  第５６回日本平滑筋学会
- Place of Presentation
  新横浜プリンスホテル（横浜市）
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] 内皮依存性、非依存性血管弛緩作用を有する魚類由来ペプチド
- Author(s)
  木村友彦、高田雄一、加治屋勝子、張影、宮成健司、岸博子、小林誠
- Organizer
  第120回日本解剖学会・第92回日本生理学会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県、神戸市）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] Effects of the Washoku-modified DASH diet on blood pressure and cardiometabolic risk factors in subjects with untreated high normal blood pressure and stage 1 hypertension
- Author(s)
  S. Umemoto, A. Kawamura, J. Inagaki, H. Kishi, K. Kajiya, M. Mitarai, K. Oda, S. Kobayashi
- Organizer
  25th European Meeting on Hypertension and Cardiovascular Protection
- Place of Presentation
  Mico Milano Congressi (Milan, Italy)
- Year and Date
  2015-06-12 – 2015-06-15
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] WASHOKU-modified DASH diet reduces blood pressure and improves cardiometabolic risk factors independently of body weight in subjects with untreated high normal blood pressure and stage 1 hypertension
- Author(s)
  A. Kawamura, S. Umemoto, J. Inagaki, H. Kishi, K. Kajiya, M. Mitarai, K. Oda, S. Kobayashi
- Organizer
  ESC Congress 2015
- Place of Presentation
  ExCeL London (London, United Kingdom)
- Year and Date
  2015-08-29 – 2015-09-02
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23380077
[Presentation] The novel role of calpain in SPC/Fyn/ROK pathway which mediates the signal transduction of abnormal vascular smooth muscle contraction
- Author(s)
  Hiroko Kishi, Ying Zhang, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+- sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23380077

1. KISHI Hiroko (40359899)

# of Collaborated Projects: 16 results

# of Collaborated Products: 138 results
2. MOGAMI Kimiko (80263771)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. ZHANG Ying (10711260)

# of Collaborated Projects: 7 results

# of Collaborated Products: 111 results
4. NISHIMURA Junji (90237727)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. KAJIYA Katsuko (00379942)

# of Collaborated Projects: 6 results

# of Collaborated Products: 27 results
6. TODOROKI Natsuko (90253153)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. KANAIDE Hideo (80038851)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
8. MIZUKAMI Yoichi (80274158)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
9. 森田知佳 (70763796)

# of Collaborated Projects: 4 results

# of Collaborated Products: 73 results
10. KAWAMICHI Hozumo (80363042)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
11. HIRANO Katsuya (80291516)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 佐藤正史 (20346547)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TAKESHITA Akira (30038814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. IMAIZUMI Tsutomu (60148947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKAMURA Shoji (80112051)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FUJIOKA Takashi (50304473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SAKATA Yoshiyuki (10034927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. AOKI Hiroki (60322244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. FUJII Kozo (90322247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YOSHIMURA Koichi (00322248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. HIRANO Mayumi (80336031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SHIGYO MASAYOSHI (40314827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. 柏木史郎 (70177369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 砂川賢二 (50163043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 澤田有司 (00415176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 山田朋宏 (50391412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 佐藤修正 (70370921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. KODAMA Yuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. LYU Bochao

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
30. ZHANG Min

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
31. LU Qian

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
32. LI Nan

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
33. KAWAMURA Atsuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. UMEMOTO Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. MITARAI Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 中村彰男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 佐藤元彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 山村彩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 永野浩昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 恒富亮一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 前田訓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 堀正敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 尾崎博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOBAYASHI Sei 小林 誠

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Identification of food component which selectively inhibits abnormal vascular contractionPrincipal Investigator

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Elucidation of mechanism for production of causal factor of vasospasmPrincipal Investigator

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Clarification of molecular mechanisms of abnormal vascular contraction by functional proteomics and a single molecular analysis of signal transductionPrincipal Investigator

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脳血管攣縮の原因シグナル分子の機能解析とその選択的阻害薬の探索Principal Investigator

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機能的プロテオミクスによる脳血管攣縮の原因分子の網羅的探索と創薬への応用Principal Investigator

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KOBAYASHI Sei 小林誠