SHIMIZU Tohru 清水徹

… Alternative Names

清水徹シミズトオル

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Researcher Number	80235655
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2008 – 2014: Kanazawa University, 医学系, 教授 2004 – 2007: Kanazawa University, Graduate School of Medical Science, Bacteriology, Professor, 医学系研究科, 教授 2004: 金沢大学, 大学院・医学研究科, 教授 2004: Kanazawa University, Graduate School of Medical Science, Professor, 大学院医学研究科, 教授 2003: 金沢大学, 医学系研究科, 助教授 … More 2003: 金沢大学, 大学院・医学研究科, 助教授 1997 – 2002: 筑波大学, 基礎医学系, 助教授 1993 – 1996: 筑波大学, 基礎医学系, 講師 1995: Department of Microbiology, Basic Medical Sciences, University of Tsukuba, Assis, 基礎医学系, 講師 1991: 筑波大学, 基礎医学系, 講師 Less
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology) / Biological Sciences Except Principal Investigator Bacteriology (including Mycology) / Biological Sciences / Applied microbiology / 細菌学
Keywords	Principal Investigator ウェルシュ菌 / Clostridium perfringens / 二成分制御系 / 病原性 / 遺伝子発現調節 / virulence / genetic regulation / 食中毒 / ガス壊疽 / DNAマイクロアレイ … More / マイクロアレイ / 遺伝子発現制御 / 細胞間情報伝達 / 発現調節 / 病原性遺伝子 / 全ゲノム配列 / 毒素 / 遺伝子発現 / virulence regulation / host factor / microarray / gas gangrene / ガス壊疸菌 / 宿主側因子 / ガス壤疽 / 病原性発現調節 / 宿主因子 / ガス壊疽菌 / gene regulation / cell-cell signaling / DNA microarray / 病原細菌 / toxin produxtion / pheromone / clostridium / 感染症治療 / Clostridium / two-component system / differential display / 転写調節 / clostridium perfringens / ニ成分制御系 / 病原因子 / ウエルシュ菌 / 細菌 / 増殖速度 / 染色体複製 / 遺伝子発現調 / 調節RNA / 芽胞 / ウェルシュ菌食中毒 / 転写調節RNA / 芽胞(胞子) / 調節RNA分子 / ストレプトリジンO / エンドサイトーシス / 細胞内寄生性細菌 / 細胞壁 / オートインデューサー / 遺伝子発現解析 / オートファジー / A群レンサ球菌 / トランスクリプトーム / ゲノム解析 / 細菌感染症 / ウェシュ菌 / Toxins / 三成分制御系 / C.pertringens / 溶血毒素 / Clostridium pesfringens … More Except Principal Investigator 黄色ブドウ球菌 / ウェルシュ菌 / 転写調節 / 熱ショック蛋白 / ストレス応答 / Clostridium perfringens / Staphylococcus aureus / 調節遺伝子 / 転写因子 / ウエルシュ菌 / ブドウ球菌 / 二成分制御系 / 病原因子 / 熱ショック応答 / パリンドローム構造 / エンテロトキシン / 細菌病原因子 / Type III secretion system / two component regulatory system / gene regulatory network / Genomic diversity / pathogenicity / Vibrio parahaemolyticus / pathogenic Escherichia coli / PCR / 2成分制御系 / マイクロアレイ / ゲノム / 腸炎ビブリオ / III型分泌系 / 発現制御ネットワーク / ゲノム多様性 / 病原性 / 賜炎ビブリオ / 病原性大腸菌 / Antibiotics / Clostridium / Transcription factors / Heat shock / Stress response mechanism / Gram Positive bacteria / 溶血毒素 / 原子力問顕微鏡 / 細胞内情報伝達 / 遺伝子発現調節 / 毒素 / ディフィシル菌 / クロストリジュウム / 環境適応 / 抗菌剤 / タカストリジュウム / 熱ショック / 菌体内情報伝達機構 / 環境応答機構 / グラム陽性菌 / two component signal transduction system / regulation of toxin production / bacterial virulence factor / stress responce gene / stress protein / stress / 二分子情報伝達系 / 溶血毒 / プロモーター構造 / アルカリショック / 2成分情報伝達系 / 熱ショック蛋白質遺伝子 / ストレス蛋白質 / ストレス蛋白 / 細菌毒素 / 毒素産生の調節機構 / ストレス応答遺伝子 / ストレス応答蛋白 / ストレス / 眼内炎 / ゼラチナーゼ / デプシペプチド / 阻害剤スクリーニング / グラム陽性日和見感染菌 / アンタゴニスト / クォルモン / 阻害剤開発 / ペプチドデザイン / 抗感染症剤 / 日和見感染 / グラム陽性細菌 / クオラムセンシング / 国際会議 / 治療法 / クロストリジウム / アルカリ応答 / 熱ショック蛋白質 / HSP70 / HSP60 / 熱ショックプロモーター / 好熱菌 / コラゲナーゼ / 熱ショックブロモーター / メチシリン耐性因子 / PCR法 / 細胞毒性因子 / 細胞付着性 / 下痢原性大腸菌 Less

Development of antipathogenic agents targeting quorum sensing of Gram-positive bacteria
- Principal Investigator
  
  NAKAYAMA Jiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Kyushu University
病原細菌の新規染色体複製システムの解明Principal Investigator
- Principal Investigator
  
  清水徹
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kanazawa University
Identification and analysis of regulatory sRNAs involved inthe pathogenicity of gas-gangrene related bacteriaPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Tohru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kanazawa University
Genetic regulation by the environmental signals in Clostridium perfringensPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Tohru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kanazawa University
Analysis in pathogenesis of bacterial lethal soft-tissue infection and application to prevention and therapy.Principal Investigator
- Principal Investigator
  
  SHIMIZU Tohru
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Research on the Regulation of Virulence by Cell-Cell Signaling in Pathogenic BacteriaPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Tohru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kanazawa University
Comprehensive analyses of bacterial pathogenesis based on the genome information
- Principal Investigator
  
  HAYASHI Tetsuya
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Miyazaki
  宮崎医科大学
ウエルシュ菌ゲノムにおける病原性調節ネットワークの包括的解析Principal Investigator
- Principal Investigator
  
  清水徹
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
ウェルシュ菌ゲノムにおける病原性調節ネットワークの包括的解析Principal Investigator
- Principal Investigator
  
  清水徹
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
クロストリジュウムの病原性に関する第3回国際会議
- Principal Investigator
  
  林英生
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
Development of antibacterial agents targeting an extracellular signal transduction.Principal Investigator
- Principal Investigator
  
  SHIMIZU Tohru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
Identification and Functional Analysis of Novel Virulence Genes in Clostridium perfringens.Principal Investigator
- Principal Investigator
  
  SHIMIZU Tohru
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
ウェルシュ菌における二成分制御系 Virレギュロンの解析Principal Investigator
- Principal Investigator
  
  清水徹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
MOLECULAR MECHANISM OF VIRULENT FACTOR PRODUCTION IN GRAM POSITIVE BACTERIA
- Principal Investigator
  
  HAYASHI Hideo
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
ウェルシュ菌の病原遺伝子調節ネットワークの解析Principal Investigator
- Principal Investigator
  
  清水徹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
黄色ブドウ球菌および好熱菌の熱ショック応答のメカニズムの解明
- Principal Investigator
  
  太田敏子
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
ウェルシュ菌における病原因子のグローバル制御機構の解析Principal Investigator
- Principal Investigator
  
  清水徹
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
ストレスによる細菌病原因子の変化・変異の分子機構
- Principal Investigator
  
  林英生
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Tsukuba
好熱菌の熱ショック応答のメカニズムに関する研究
- Principal Investigator
  
  太田敏子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
ウェルシュ菌・theta-毒素遺伝子発現調節機構の分子生物学的解析Principal Investigator
- Principal Investigator
  
  清水徹
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
Stresses and Stress Proteins That Regulate Pathogenesis of Virulent Bacteria.
- Principal Investigator
  
  HAYASH Hideo
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Tsukuba
病原性未確定大腸菌の病原性因子の解媒
- Principal Investigator
  
  HAYASH Hideo
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  University of Tsukuba

[Book] RNA実験ノート・下2008
- Author(s)
  清水徹
- Total Pages
  133
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17019021
[Book] Clostridium、「ゲノミクス・プロテオミクスの新展開〜生物情報の解析と応用〜」2004
- Author(s)
  林英生, 清水徹
- Total Pages
  1158
- Publisher
  エヌ・ティー・エス
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390140
[Journal Article] Complex transcriptional regulation of citrate metabolism in Clostridium perfringens2012
- Author(s)
  Yuan, Y., Ohtani, K., Yoshizawa, S., Shimizu, T
- Journal Title
  
  Anaerobe
  
  Volume: 18 Issue: 1 Pages: 48-54
- DOI
  10.1016/j.anaerobe.2011.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390081
[Journal Article] Genetic and biochemical analysis of a class C nonspecific acid phosphatase (NSAP) of Clostridium perfringens2010
- Author(s)
  Wang, R., Ohtani, K., Wang, Y., Yuan, Y., Hassan, S., Shimizu, T.
- Journal Title
  
  Microbiol 156
  
  Pages: 167-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Identification of a two-component VirR/Vir S regulon in Clostridium perfringens2010
- Author(s)
  Ohtani, K., Hirakawa, H., Tashiro, K., Yoshizawa, S., Kuhara, S., Shimizu, T
- Journal Title
  
  Anaerobe
  
  Volume: 16 Issue: 3 Pages: 258-264
- DOI
  10.1016/j.anaerobe.2009.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390081
[Journal Article] Global regulation of gene expression in response to cysteine availability in Clostridium perfringens2010
- Author(s)
  Andre, G., Haudecoeur, E., Monot, M., Ohtani, K., Shimizu, T.,(他)
- Journal Title
  
  BMC Microbiol
  
  Volume: 10 Issue: 1 Pages: 234-234
- DOI
  10.1186/1471-2180-10-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390081
[Journal Article] Identification of a two-component VirR/VirS regulon in Clostridium perfringens2010
- Author(s)
  Ohtani, K., Hirakawa, H., Tashiro, K., Yoshizawa, S., Kuhara, S., Shimizu, T.
- Journal Title
  
  Anaerobe (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Contact with enterocyte-like Caco-2 cells induces rapid upregulation of toxin production by Clostridium perfringens type C isolates2009
- Author(s)
  Vidal, J.E., Ohtani, K., Shimizu, T., McClane, B.A.
- Journal Title
  
  Cell. Microbiol. 11
  
  Pages: 1306-1328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Virulence gene regulation by the agr system in Clostridium perfringens2009
- Author(s)
  Ohtani, K., Yuan, Y., Hassan, S., Wang, R., Wang, Y., Shimizu, T.
- Journal Title
  
  J. Bacteriol. 191
  
  Pages: 3919-3927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Carbon catabolite repression of type IV pilus-dependent gliding motility in the anaerobic pathogen Clostridium perfringens2008
- Author(s)
  Mendez, M., Huang, I.H., Ohtani, K., Grau, R., Shimizu, T., Sarker, M.R.
- Journal Title
  
  J. Bacteriol. 190
  
  Pages: 48-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Carbon catabolite repression of type IV pilus-dependent gliding motility in the anaerobic pathogen Clostridium perfringens.2008
- Author(s)
  Mendez, M., I. H. Huang, K. Ohtani, R. Grau, T. Shimizu, M. R. Sarker.
- Journal Title
  
  J. Bacteriol. 190
  
  Pages: 48-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Characterization of genes regulated directly by the VirR/VirS system in Clostridium perfringens2008
- Author(s)
  Okumura, K., K. Ohtani, H. Hayashi, T. Shimizu.
- Journal Title
  
  J. Bacteriol. 190
  
  Pages: 7719-7727
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Characterization of genes regulated directly by the VirR/VirS system in Clostridium perfringens.2008
- Author(s)
  Okumura, K., K. Ohtani, H. Hayashi, T. Shimizu.
- Journal Title
  
  J. Bacteriol. 190
  
  Pages: 7719-7727
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Characterization of Genes Regulated Directly by the VirR/VirS System in Clostridium perfringens2008
- Author(s)
  Okumura, K., Ohtani, K., Hayashi, H., Shimizu, T.
- Journal Title
  
  J. Bacteriol. 190(23)
  
  Pages: 7719-7727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Carbon catabolite repression of type IV pilus-dependent gliding motility in the anaerobic pathogen Clostridium perfringens2008
- Author(s)
  Mendez M., Huang IH., Ohtani K., Grau R., Shimizu T. and Sarker, MR.
- Journal Title
  
  J. Bacteriol. 190
  
  Pages: 48-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Cazbon catabolite repression of type IV pilus-dependent gliding motility in the anaerobic pathogen Clistrudium perfringens2008
- Author(s)
  Mendez M., Huang IH., Ohtani K., GrauR., Shimizu T .nd Sarker, MR
- Journal Title
  
  J.Bacteriol. 190
  
  Pages: 48-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Complete genome sequence of Finegoldia magna, an anaerobic opportunistic pathogen.2008
- Author(s)
  Goto, T., A. Yamashita, H. Hirakawa, M. Matsutani, K. Todo, K. Ohshima, H. Toh, K. Miyamoto, S. Kuhara, M. Hattori, T. Shimizu, S. Akimoto.
- Journal Title
  
  DNA Res. 15
  
  Pages: 39-47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Carbon catabolite repression of type IV pilus-dependent gliding motility in theanaerobic pathogen Clostridium perfringens.2008
- Author(s)
  Mendez, M., H. Huang, K. Ohtani, R. Grau. T. Shimizu. M. R. Sarker.
- Journal Title
  
  J. Bacteriol. 190
  
  Pages: 48-60
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Detection of a group II intron without open reading frame in the alpha toxin gene of Clostridium perfringens isolated from a broiler chicken2007
- Author(s)
  Ma, M., Ohtani, K., Shimizu, T., and Misawa, N.
- Journal Title
  
  J. Bacteriol. 189
  
  Pages: 1633-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Detection of a group II intron without open reading frame in the alpha toxin gene of Clostridium perfringens isolated from a broiler chicken2007
- Author(s)
  Ma, M., Ohtani. K., Shimizu. T., and Misawa, N.
- Journal Title
  
  J.Bacteriol. 189
  
  Pages: 1633-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Detection of a group II intron without open reading frame in the alpha toxin gene of Clostridium perfringens isolated from a broiler chicken2007
- Author(s)
  Ma, M., Ohtani, K., Shimizu, T., Misawa, N.
- Journal Title
  
  J.Bacteriol. 60
  
  Pages: 1633-1640
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Detection of a group II intron without open reading frame in the alphatoxin gene of Clostridium perfringens isolated from a broiler chicken2007
- Author(s)
  Ma, M., Ohtani, K., Shimizu, T., Misawa, N.
- Journal Title
  
  J. Bacteriol. 60
  
  Pages: 1633-1640
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Detection of a group II intron without open reading frame in the alpha toxin gene of Clostridium perfringens isolated from a broiler chicken2007
- Author(s)
  Ma, M., Ohtani, K., Shimizu, T., Misawa, N.
- Journal Title
  
  J. Bacteriol. 60
  
  Pages: 1633-1640
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Detection of a group II intron without an open reading frame in the alpha-toxin gene of Clostridium perfringens isolated from a broiler chicken.2007
- Author(s)
  Ma, M., K. Ohtani, T. Shimizu, N. Misawa.
- Journal Title
  
  J. Bacteriol. 189
  
  Pages: 1633-1640
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Identification and characterization of a cell-wall anchored DNase gene in Clostridium perfringens2005
- Author(s)
  K.Okumura, H.I.Kawsar, T.Shimizu, T.Ohta, H.Hayashi, T.Shimizu
- Journal Title
  
  FEMS Microbiol.Lett. 242
  
  Pages: 281-285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390140
[Journal Article] Identification and characterization of a cell-wall anchored DNase gene in Clostridium perfringens2005
- Author(s)
  Okumura, K., Kawsar, H.I., Shimizu, T., Ohta T.,, Hayashi H., Shimizu, T.
- Journal Title
  
  FEMS Microbiol. Lett. 242
  
  Pages: 281-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] ウェルシュ菌のゲノム構造の解析と病原遺伝子発現調節機構の解明2004
- Author(s)
  清水徹
- Journal Title
  
  日本細菌学会雑誌 59
  
  Pages: 377-385
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390140
[Journal Article] ウェルシュ菌のシグナル伝達機構2004
- Author(s)
  清水徹, 大谷郁, 中村信一
- Journal Title
  
  臨床と微生物 31
  
  Pages: 229-237
- NAID
  80016700496
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390140
[Journal Article] DNAマイクロアレイの応用2004
- Author(s)
  清水徹
- Journal Title
  
  微生物はなぜ病気をおこすかゲノムの特徴(林英生編集)
  
  Pages: 160-167
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] ウェルシュ菌のシグナル伝達機構2004
- Author(s)
  清水徹, 大谷郁, 中村信一
- Journal Title
  
  臨床と微生物 31
  
  Pages: 229-237
- NAID
  80016700496
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] Clostridium2004
- Author(s)
  林英生, 清水徹
- Journal Title
  
  ゲノミクス・プロテオミクスの新展開生物情報の解析と応用(今中忠行監修)
  
  Pages: 256-267
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] クロストリジウム2004
- Author(s)
  清水徹
- Journal Title
  
  微生物はなぜ病気をおこすかゲノムの特徴(林英生編集)
  
  Pages: 91-99
- NAID
  10016519982
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] Organization and transcriptional regulation of myo-Inositol operon in Closiridium perfringens2004
- Author(s)
  H.I.Kawsar, K.Ohtani, K.Okurnura, H.Hayashi, T.Shimizu
- Journal Title
  
  FEMS Microbiol.Lett. 235
  
  Pages: 289-295
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390140
[Journal Article] ゲノムから解くヒト病原微生物クロストリジウム2004
- Author(s)
  清水徹
- Journal Title
  
  化学と生物 42
  
  Pages: 674-679
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] 5.クロストリジウム2004
- Author(s)
  清水徹
- Journal Title
  
  化学と生物 42
  
  Pages: 674-679
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390140
[Journal Article] ウェルシュ菌のゲノム構造の解析と病原遺伝子発現調節機構の解明2004
- Author(s)
  清水徹
- Journal Title
  
  日本細菌学雑誌 59
  
  Pages: 377-385
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] 病原細菌のゲノム構造2004
- Author(s)
  林英生, 清水徹, 太田敏子
- Journal Title
  
  「医学をゲノムする」阿蘇シンポジュウム記録2003
  
  Pages: 15-45
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] Clostridial VirR/VirS regulon involves a regulatory RNA molecule for expression of toxins.2002
- Author(s)
  T.Shimizu, et al.
- Journal Title
  
  Mol.Microbiol. 43
  
  Pages: 257-265
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] Proteome and transcriptome analysis of the virulence genes regulated by the VirR/VirS system in Clostridium perfringens.2002
- Author(s)
  T.Shimizu, et al.
- Journal Title
  
  J.Bacteriol. 184
  
  Pages: 2587-2594
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] Proteome and transcriptome analysis of the virulence genes regulated by the VirR/VirS system in Clostridium perfringens.2002
- Author(s)
  T.Shimizu, et al.
- Journal Title
  
  J. Bacteriol. 184
  
  Pages: 2587-2594
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater2002
- Author(s)
  T.Shimizu, et al.
- Journal Title
  
  Proc. Natl. Acad.Sci. USA 99
  
  Pages: 996-1001
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater,2002
- Author(s)
  T.Shimizu, et al.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 99
  
  Pages: 996-1001
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] Clostridial VirR/VirS regulon involves a regulatory RNA molecule for expression of toxins2002
- Author(s)
  T.Shimizu, et al.
- Journal Title
  
  Mol. Microbiol. 43
  
  Pages: 257-265
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14014241
[Journal Article] Complete genome sequence of Finegoldia magna, an anaerobic opportumistic pathogen
- Author(s)
  Goto T., Yamashita A., Hirakawa H., Matsutani M., Todo K., Ohshima K., Toh H., Miyamoto K., Kuhara S., Hattori M., Shimizu T. and Akimoto S.
- Journal Title
  
  RNA Res. (印刷中)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590415
[Journal Article] Unique regulatory mechanism of sporulation and enterotoxin production in Clostridium perfringens
- Author(s)
  Ohtani, K., Hirakawa, H., Paredes-Sabja, D., Tashiro, K., Kuhara, S., Sarker, M., Shimizu, T
- Journal Title
  
  J. Bacteriol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390081
[Patent] クロストリジウム属の菌の毒素産生抑制活性を有するペプチド2015
- Inventor(s)
  清水徹、大谷郁、中山二郎、高橋志達、岡健太郎ら
- Industrial Property Rights Holder
  高橋志達、岡健太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2015-02-04
- Overseas
- Data Source
  KAKENHI-PROJECT-24380050
[Patent] クロストリジウム属の菌の毒素産生抑制活性を有するペプチド2014
- Inventor(s)
  清水徹、大谷郁、中山二郎、高橋志達、岡健太郎ら
- Industrial Property Rights Holder
  高橋志達、岡健太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-24380050
[Presentation] ウェルシュ菌における内在性クオラムクエンチング誘導物質の精製2014
- Author(s)
  河野通生、大谷郁、Ravindra Pal Singh、石橋直樹、園元謙二、清水徹、中山二郎
- Organizer
  第21回生物工学会九州支部熊本大会
- Place of Presentation
  熊本大学工学部
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24380050
[Presentation] 放線菌の生産する環状デプシペプチドによるクオラムセンシング阻害作用機構の解明2014
- Author(s)
  庄島あかね、松藤貴久、Said E. Desouky、大久保謙一、Ravindra Pal Singh、清水徹、大谷郁、五十嵐康弘、園元謙二、中山二郎
- Organizer
  第21回生物工学会九州支部熊本大会
- Place of Presentation
  熊本大学工学部
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24380050
[Presentation] Novel regulatory mechanism for spore formation and enterotoxin production in Clostridium perfringens2013
- Author(s)
  大谷郁, Huyen Hoang, 清水徹
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ国際会議場(千葉県)
- Year and Date
  2013-03-18
- Data Source
  KAKENHI-PROJECT-22390081
[Presentation] ウェルシュ菌における芽胞形成ならびにエンテロトキシン産生調節機構の解析2013
- Author(s)
  大谷　郁、Hoang, H.、清水　徹
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  千葉県千葉市　幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-24659195
[Presentation] Nove; regulatory mechanism for sopre formation and enterotoxin production in Clostridium perfringens2011
- Author(s)
  Ohtani, K., Hirakawa, H., Paredes-Sabja, D., Tashiro, K., Kuhara, S., Sarker, M., Shimizu, T
- Organizer
  7th International Conference on the Molecular Biology and Pathogenesis o the Clostridia
- Place of Presentation
  Iowa State Center (Ames, Iowa, USA)
- Data Source
  KAKENHI-PROJECT-22390081
[Presentation] Complex regulatory networks for virulence in Clostridium perfringens2009
- Author(s)
  Shimizu, T
- Organizer
  The 6th Clostridia: The Impact of Genomics on Disease Control
- Place of Presentation
  Instito Superiore di Sanita
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-17019021
[Presentation] Complex regulatory networks for virulence in C.perfringens2009
- Author(s)
  Shimizu, T.
- Organizer
  Clostridia : The Impact of Genomics on Disease Control
- Place of Presentation
  ローマ高等衛生院(イタリア)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-17019021
[Presentation] Effect of bacterial and host factors on gene expression in Clostridium perfringens2007
- Author(s)
  Ohtani, K., Isu, A., Ohkubo, J., Shimizu, T.
- Organizer
  107th General Meeting of American Society for Microbiology
- Place of Presentation
  トロント(カナダ)
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-17019021
[Presentation] Effect of host factors on gene expression in Clostridium perfringens.2007
- Author(s)
  K. Ohtani, A. Isu, J. Ohkubo, T. Shimizu.
- Organizer
  107^<th> ASM General Meeting
- Place of Presentation
  トロント、カナダ
- Year and Date
  2007-05-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590415
[Presentation] Effect of bacterial and host factors on gene expression in Clostridium perfringens.2007
- Author(s)
  K. Ohtani, A. Isu, J. Ohkubo, T. Shimizu.
- Organizer
  107^<th> ASM General Meeting
- Place of Presentation
  Tronto, Canada
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590415
[Presentation] Functional analysis of the transcriptional regulatory RNA, VR,-RNA in Clostridium perfringens2007
- Author(s)
  R.Wang, K.Ohtani, A.Hassan, T.Shimizu
- Organizer
  107th General Meeting of American Society for Microbiology
- Place of Presentation
  トロント(カナダ)
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-18590415
[Presentation] Biological signaling to gene expression in Clostridium perfringens.2006
- Author(s)
  K. Ohtani, K. Tanaka, K. Hasatani, K. Miwa, A. Isu, T. Shimizu.
- Organizer
  5^<th> International Meeting on the Molecular Biology and Pahogenesis of the Clostridia.
- Place of Presentation
  Nottingham, UK.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590415
[Presentation] Identification of autoinducing peptide of Clostridium perfringens and development of its inhibitors
- Author(s)
  Ravindra Pal Singh, Kaori Ohtani, Ryoji Yokohata, Kenji Sonomoto, Toru Shimizu, Jiro Nakayama
- Organizer
  5th ASM conference on cell-cell communicaion in bacteria
- Place of Presentation
  San Antonio
- Year and Date
  2014-10-18 – 2014-10-21
- Data Source
  KAKENHI-PROJECT-24380050

1. HAYASH Hideo (40033203)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. OHTA Toshiko (40233134)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. OHTANI Kaori (30377410)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
4. KURAZONO Hisao (90186487)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 青木泰子 (80202480)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKAGAWA Ichiro (70294113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKAYAMA Jiro (40217930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. NAGATA Koji (30280788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IGARASHI Yasuhiro (20285159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. SUZUKI Takashi (70398048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAMURA Shinichi (90019620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HAYASHI Tetsuya (10173014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. OGURA Yoshitoshi (40363585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OOKA Tadasuke (50363594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TOBE Toru (70207596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. IIDA Tetsuya (90221746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. OZAKI Eijirou (40334750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小池和子 (60110508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 渡邊邦友 (70108067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 小崎俊司 (10109895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 神谷茂 (10177587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 杉本央 (20142317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 中山恵介 (10347057)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 大西真 (10233214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMIZU Tohru 清水 徹

清水 徹 シミズ トオル

Research Projects

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病原細菌の新規染色体複製システムの解明Principal Investigator

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Identification and analysis of regulatory sRNAs involved inthe pathogenicity of gas-gangrene related bacteriaPrincipal Investigator

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Genetic regulation by the environmental signals in Clostridium perfringensPrincipal Investigator

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Analysis in pathogenesis of bacterial lethal soft-tissue infection and application to prevention and therapy.Principal Investigator

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Research on the Regulation of Virulence by Cell-Cell Signaling in Pathogenic BacteriaPrincipal Investigator

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ウエルシュ菌ゲノムにおける病原性調節ネットワークの包括的解析Principal Investigator

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ウェルシュ菌ゲノムにおける病原性調節ネットワークの包括的解析Principal Investigator

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Development of antibacterial agents targeting an extracellular signal transduction.Principal Investigator

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Identification and Functional Analysis of Novel Virulence Genes in Clostridium perfringens.Principal Investigator

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ウェルシュ菌における二成分制御系 Virレギュロンの解析Principal Investigator

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SHIMIZU Tohru 清水徹

清水徹シミズトオル