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NAKAHARA Kenji  中原 健次

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… Alternative Names

中原 健次  ナカハラ ケンジ

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Researcher Number 80250934
Affiliation (based on the past Project Information) *help 2007: Yamagata University, Faculty of Medicine, Associate Professor
1999 – 2006: Dep Ob-Gyn, School of Medicine, Yamagata University, Assist. Professor, 医学部, 講師
2004: 国立大学法人山形大学, 医学部, 講師
1996 – 1998: Yamagata Univ.OB/GYN Assistant, 医学部, 助手
1994: 山形大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology / Obstetrics and gynecology / Biological Sciences
Keywords
Principal Investigator
顆粒膜細胞 / アポトーシス / 卵巣 / INTRACELLULAR SIGNAL TRANSDUCTION / GRANULOSA CELL / ATRESIA OF FOLLICLE / OVARY / APOPTOSIS / 卵胞閉鎖 / 卵胞 … More / シグナル伝達 / 卵の質 / 細胞内シグナル伝達 / マウス / マクロファージ / 卵胞発育 / growth hormone / NO / Steroidgenesis … More
Except Principal Investigator
cyclin D1 / アポトーシス / テロメラーゼ / 細胞周期 / MAPキナーゼ / CD44 / 卵胞 / 転写制御 / 上皮成長因子(EGF) / エストロゲン / エストロゲン受容体 / anti cancer drug / sienal transduction / EGF receptor / molecular tareeted therapy / ovanan cancer / DNA損傷 / EGF受容体(EGFR) / 抗癌剤 / シグナル伝達経路 / EGF受容体 / 分子標的治療 / 卵巣癌 / mammary carcinoma / selective estrogen receptor modulator / MAP kinase pathway / phosphorylation / apoptosis / atherosclerosis / estrogen receptor / 細胞内情報伝達 / p38経路 / プロモーター / Rb蛋白 / サイクリンD1 / 増殖 / nongenomicな作用 / NFκB経路 / Akt / PI3K / 血管平滑筋 / ラロキシフェン / 乳がん / 選択的エストロゲン受容体修飾薬 / MAPキナーゼ経路 / リン酸化 / 動脈硬化 / glutathione reductase / 8 OhdG / cell cycle / oxidative stress / quality of oocyte / ヒアルロン酸 / 凍結 / 胚 / 卵 / グルタチオンリダクターゼ / 8-OHdG / 酸化ストレス / 卵の質 / gene transcription / epidermal growth factor (EGF) / integrin / chemokinesis / invasion / adhesion molecule / trophoblast / 転写因子 / 細胞浸潤 / ケモタキシス / 細胞浸潤能 / 上皮成長因子 (EGF) / 細胞接着因子 / 絨毛細胞 / インテグリン / 遊走能 / 浸潤能 / 接着因子 / 繊毛細胞 / Apoptosis / Steroidogenesis / Granulosa Cell / Ovarian follicle / 卵透明帯 / アポトージス / steroid産生 / 顆粒膜細胞 / microinsemination / Ca-oscillation / oviduct glycoprotein / embryo / fertilization / 子宮筋gap junction / 卵管因子 / 精子 / 卵子 / アポト-ジス / 細胞内カルシウム / steroidogenesis / 卵の糖代謝 / 卵管分泌性糖蛋白 / 透明帯 / 顕微授精 / カルシウムオスシレーション / 顕微受精 / カルシウム オスシレーション / 卵管特異糖蛋白 / 胚発育 / 受精 / 共焦点レーザー顕微鏡 / 蛍光顕微鏡 / AF-2ドメイン / 変異遺伝子 / GFPキメラ蛋白 / 核内分布 / シグナル伝達 / 欠失変異 / インスリン様増殖因子(IGF)-1 / BAD / Akt経路 / ERK経路 / アポトーシス関連因子 / シグナル伝達関連因子 / マウス卵巣癌モデル / タキソール耐性 / シスプラチン耐性 Less
  • Research Projects

    (12 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (27 People)
  •  Study for the development of molecular therapy targeting the signal transduction pathway through epidermal growth factor receptor

    • Principal Investigator
      KURACHI Hirohisa
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yamagata University
  •  卵巣癌の薬剤耐性化機構の解明と耐性化に関与する分子を標的とする治療法の開発

    • Principal Investigator
      OUMICHI Masahide
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  リガンド依存性・非依存性のエストロゲン受容体活性化と核内分布変化を可視化する試み

    • Principal Investigator
      倉智 博久
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yamagata University
  •  Antiatherogenic action of estrogen through inhibition of pathological proliferation in vascular smooth muscle sells

    • Principal Investigator
      KURACHI Hirohisa
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yamagata University
  •  EVALUATION OF OOCYTES QUALITY THOROUGH ANALYSIS OF APOPTOTIC SIGNAL TRANSDUCTION IN FOLLICLES.Principal Investigator

    • Principal Investigator
      NAKAHARA Kenji
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      YAMAGATA UNIVERSITY
  •  Study of factors regulating the development of follicles, oocytes and embryos

    • Principal Investigator
      SAITO Hidekazu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yamagata University
  •  ELUCIDATION OF MAKING ATRETIC FOLLICLES VIA APOPTOSIS AND MECHANISM OF INTRACELLULAR APOPTOTIC SIGNALSPrincipal Investigator

    • Principal Investigator
      NAKAHARA Kenji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      YAMAGATA UNIVERSITY
  •  Differentiation- dependent regulation of adhesion molecules in trophoblast cells

    • Principal Investigator
      KURACHI Hirohisa, 西尾 幸浩
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yamagata University
      Osaka University
  •  Studies on the regulatory mechanism of interaction between the development of ovulatry follicle and ovum in the ovary.

    • Principal Investigator
      HIROI Masahiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      YAMAGATA UNIVERSITY
  •  卵胞発育・閉鎖機構における免疫機序および黄体退縮機序の解明Principal Investigator

    • Principal Investigator
      中原 健次
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yamagata University
  •  亜鉛及び銅イオン動態がステロイドホルモン・レセプター動態に及ぼす影響Principal Investigator

    • Principal Investigator
      中原 健次
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yamagata University
  •  Mechanism of fertilization and embryo development

    • Principal Investigator
      HIROI Masahiko
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yamagata University

All 2006

All Journal Article

  • [Journal Article] Clinical outcome and risk factors for recurrence in borderline ovarian tumours.2006

    • Author(s)
      Yokoyama Y, Moriya T, Takano T, Shoji T, Takahasi O, Nakahara K, Yamada H, Yaegashi N, Okamura K, Izutsu T, Sugiyama T, Tanaka T, Kurachi H, Sato A, Tase T, Mizunuma H.
    • Journal Title

      Br J Cancer 94(11)

      Pages: 1586-1591

    • Data Source
      KAKENHI-PROJECT-17390445
  • [Journal Article] Usefulness of intraovarian artery pulsatility and resistance indices measurement on the day of follicle aspiration for the assessment of oocyte quality.2006

    • Author(s)
      Du B, Takahashi K, Ishida GM, Nakahara K, Saito H, Kurachi H.
    • Journal Title

      Fertil Steril 85(2)

      Pages: 366-370

    • Data Source
      KAKENHI-PROJECT-17390445
  • 1.  KURACHI Hirohisa (40153366)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 2 results
  • 2.  SAITO Hidekazu (90125766)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  TAKAHASHI Kazuhiro (20292427)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 4.  SAITO Takakazu (00272071)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  OUMICHI Masahide (10283764)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  TANAKA Eiichi (20322000)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  HIROI Masahiko (60018364)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SAKATA Masahiro (10260639)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TEZUKA Naohiro (60261690)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  TAKAHASHI Toshifumi (20302292)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  KAWACHIYA Satoshi (30322001)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  ARAKI Yoshihiko (70250933)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  HIRAYAMA Toshio (60238392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ITOH Mariko (40292429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  YAMAMOTO Toshiya (80283787)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MORISHIGE Kenichirou (90283788)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TUTUMI Seiji (50323168)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  ABE Akiko (30359567)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HAYASAKA Tadashi (10375339)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  田坂 慶一 (50155058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  五十嵐 秀樹 (80333970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  小宮 雄一 (70234888)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  川越 慎之助 (10018880)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  太田 信彦 (40301072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  西尾 幸浩 (30303952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  清野 朝史 (00311580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  吉田 雅人 (20312738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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