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ISEKI Sachiko  井関 祥子

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… Alternative Names

井関 祥子  イセキ サチコ

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Researcher Number 80251544
Other IDs
External Links
Affiliation (Current) 2025: 東京科学大学, 大学院医歯学総合研究科, 教授
Affiliation (based on the past Project Information) *help 2015 – 2024: 東京医科歯科大学, 大学院医歯学総合研究科, 教授
2012 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 教授
2012: 東京医科歯科大学, 大学院・医歯学総合研, 教授
2010 – 2012: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 教授
2009 – 2010: Tokyo Medical and Dental University, 医歯学総合研究科, 教授 … More
2008: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 教授
2007: Tokyo Medical and Dental University, Graduate School of dentistry, Assistant Professor
2005: Tokyo Medical and Dental University, Graduate School, Research Assoociate, 大学院医歯学総合研究科, 助手
1999 – 2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 助手
1998: Tokyo Medical and Dental Univercity, Developmental Biology, Research Asoosiate, 歯学研究科, 助手
1994: 徳島大学, 歯学部, 助手 Less
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Basic Section 56070:Plastic and reconstructive surgery-related / Plastic surgery / Basic Section 57010:Oral biological science-related / Medium-sized Section 57:Oral science and related fields / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Morphological basic dentistry / Surgical dentistry
Except Principal Investigator
Surgical dentistry / Basic Section 48010:Anatomy-related … More / Morphological basic dentistry / Basic Section 56070:Plastic and reconstructive surgery-related / Basic Section 56020:Orthopedics-related / Medium-sized Section 52:General internal medicine and related fields / Basic Section 57060:Surgical dentistry-related / Biomedical engineering/Biomaterial science and engineering / Plastic surgery / Functional basic dentistry / General surgery / Functional basic dentistry / Morphological basic dentistry / Periodontal dentistry / Orthodontic/Pediatric dentistry Less
Keywords
Principal Investigator
頭蓋冠 / 骨芽細胞 / 頭蓋縫合早期癒合症 / Twist / 頭蓋骨癒合症 / 神経堤 / 中胚葉 / 骨修復 / 骨芽細胞分化 / ポリロタキサン … More / TWiST / FGF / meninges / skull vault / 髄膜層 / 線維芽細胞増殖因子 / 子宮外胎児手術法 / 線維芽細胞増殖因子受容体 / 縫合 / 神経堤細胞 / heterogeneity / 頭蓋骨 / 組織由来 / 頭蓋冠骨 / メカノシグナル / マクロファージ / 頭蓋冠幹細胞 / ナノゲル / 骨欠損 / 骨髄間質細胞 / M2マクロファージ / BMP2 / FGF18 / 膜性骨 / マウス頭蓋冠 / X線μCT画像 / 骨格形態 / X線microCT / 幾何学的形態解析法 / 形態 / 定量化 / 機械学習 / 成長 / 頭蓋 / エピジェネティクス / 遺伝子発現パターン / 遺伝子発現プロファイル / 遺伝子発現 / iPS / iPS細胞 / 再生医学 / 歯学 / 発生分化 / 生体分子 / 外科 / polyrotaxane / diffferentiation / osteoblast / craniosynostosis / osteogenesis inhibition / tooth root formation / suture / 硬膜 / 哺乳類 / 骨分化 / 縫合閉鎖 / マウス胎児 / 冠状縫合 / DNAアレイ / noggin / BMP / 歯根形成 / 骨形成抑制 / 髄膜 / osteogenesis / ex-utero surgery / adenoviral vector / 増殖と分化 / 骨 / 骨形成 / アデノウイルスベクター / 舌 / 組織特異的エンハンサー / MFCS4 / 定量的ISH / Shh / 口蓋裂 / エンハンサー / 口蓋 / ソニックヘッジホッグ / 病態検査学 / 頭蓋冠発生 / TWIST / in situ hybridization / マウス胚 / transformation … More
Except Principal Investigator
神経堤細胞 / 頭蓋縫合早期癒合症 / 頭部神経堤細胞 / 腱 / 口蓋裂 / 先天性疾患 / Twist / 全胚培養と上顎器官培養 / メッケル軟骨 / 鰓弓 / 長期器官培養 / 歯胚 / 蛍光色素 / 前腸内胚葉 / 哺乳類全胚培養 / 下顎器官培養 / 舌 / 再生医療 / 組織再生 / iPS細胞 / suturectomy / refusion / treatment / Craniosynostosis / 細胞系譜解析 / 頭骸骨 / アクチン / 頭部骨格筋 / コラーゲン / 軟骨頭蓋 / 皮骨頭蓋 / クローン解析 / 靱帯 / 異所性骨化 / 筋骨格系 / 連結組織 / 心臓ー頭頸部 / エピゲノム解析 / ヒストン修飾因子 / 非コードRNA / 3D空間解析 / 心疾患重症化 / 先天異常 / エピジェネティクス / 低酸素症 / 唇顎口蓋裂 / 唇顎裂 / 動物実験 / マウス / 低酸素 / 口唇口蓋裂 / 唇裂 / 頭蓋顎顔面 / 疾患モデルマウス / スプライシング因子 / スプライソソーム症 / Pladienolide B / Pladienolide-B / Sf3b1 / Sf3b4 / スプライソソーム / スプライシング / Nager症候群 / 分子可動性 / 歯根膜細胞 / スキャホールド / 分子運動性 / ポリロタキサン / SHH / Shh / Sonic hedgehog / 内舌筋 / 外科 / 頭蓋骨縫合早期癒合症 / 治療 / マウスモデル / Twist1 / 成長 / 再癒合 / 手術 / 冠状縫合 / 頭蓋縫合早期癒合 / 骨再生 / ミエリンプロテインゼロ / 骨芽細胞 / 毛包 / 神経堤由来細胞 / iPS cell / ex utero surgery / Hepatoblast / Bile duct / Cell transplantation / Regenerative medicine / Hepatocyte / ES cell / 肝外胆管 / 肝機能障害治療 / ex utero移植法 / 肝芽細胞 / 胆管 / 細胞移植 / 肝細胞 / ES細胞 / Tissue regeneration / Cell differentiation / Cell proliferation / Cell-based therapy / in situ Tissue Engineering / Cranial Neural Crest Stem Cells / Cranial Neural Crest Cells / GFP遺伝子導入マウス / 全胚培養 / 頭部間葉 / 哺乳類頭部神経堤細胞 / DNazyme / 凍結保存 / LacZ遺伝子導入マウス / 頭蓋顔面部の組織再生 / 哺乳類頭部神経堤幹細胞 / 細胞培養 / 細胞分離 / 幹細胞 / 再生 / 遺伝子プロファイリング / in situ tissue engineering / 細胞分化 / 細胞増殖 / 頭部神経堤幹細胞 / vertebrates / growth center / cranial mesoderm / tissue boundary / cranial neural crest / foregut endoderm / ectoderm / cranioiaciai development / 歯胚形成のinitiation / アデノウイルス標識 / BMP-MSXカスケード / Fgf-8 / shh / 上皮-間葉相互作用 / 口咽頭膜 / ラトケ嚢 / 中脳の神経堤細胞 / シグナリング機構 / 顎の発生機序 / 口腔上皮 / Wnt-1遺伝子 / 頭蓋縫合 / 中胚葉 / 頭蓋冠 / 成長中心 / 脊椎動物 / 頭部中胚葉 / 組織境界 / 外胚葉 / 頭部発生 / Mandibular organ culture / Whole embryo culture / Long-term culture / Foregut endoderm / Neural crest cells / Tooth development / 器官培養 / アデノウイルス / 鼻咽腔閉鎖機能 / 軟骨 / Shh / 血管構築 / 星状網 / エナメル器 / 上皮間葉転換 / 血管新生 / 歯の発生 / IL-1β / Txnip / Trx1 / 歯周ポケット / ROS / 組織の酸化状態 / TRX / ポケット上皮 / Txnip(thioredoxin interacting protein) / TRX1(チオレドキシン 1) / 酸化ストレス / 歯周免疫機能学 / エンハンサー / ソニックヘッジホック / ソニック:ヘッジホッグ / 口蓋 / 病態検査学 / 歯根吸収 / TGF-β / DSPP / 下顎骨 / 上顎骨 / 形態異常 / 3次元構築 / 歯根 Less
  • Research Projects

    (31 results)
  • Research Products

    (120 results)
  • Co-Researchers

    (64 People)
  •  頭蓋顎顔面修復への応用を目指した、heterogeneticな組織/細胞の動態解明Principal Investigator

    • Principal Investigator
      井関 祥子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Tokyo Medical and Dental University
  •  老化や損傷および疾患で破綻する腱・靱帯の異所性骨化抑制メカニズムの解明

    • Principal Investigator
      吉本 由紀
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒトiPS細胞由来間葉系幹細胞を用いたin vitro頭蓋縫合早期癒合症モデルPrincipal Investigator

    • Principal Investigator
      井関 祥子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Establishment of novel cell lineage analysis for understanding congenital craniofacial anomalies

    • Principal Investigator
      足立 礼孝
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      Tokyo Medical and Dental University
  •  頭蓋縫合早期癒合におけるゴアテックス人工硬膜を用いた再癒合阻害の試み

    • Principal Investigator
      塗 隆志
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  Analysis of heterogenous character of neural crest-derived osteoblastsPrincipal Investigator

    • Principal Investigator
      井関 祥子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  Understanding the functional analysis of the epigenetic regulation in congenital cardio-craniofacial-limb defects

    • Principal Investigator
      竹内 純
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  Cellular dynamics in calvarial bone healingPrincipal Investigator

    • Principal Investigator
      ISEKI Sachiko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Tokyo Medical and Dental University
  •  顎顔面発生のエピジェネティクス解析:低酸素環境の及ぼす影響

    • Principal Investigator
      長岡 亮介
    • Project Period (FY)
      2019 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Developmental etiology of craniofacial abnormalities in Nager syndrome

    • Principal Investigator
      Takechi Masaski
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      Juntendo University
      Tokyo Medical and Dental University
  •  Quantification of craniofacial growth by machine learningPrincipal Investigator

    • Principal Investigator
      Sachiko Iseki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  Classification and pathological elucidation of Craniosynostosis by the differentiation's pattern of iPS cellsPrincipal Investigator

    • Principal Investigator
      Iseki Sachiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Plastic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of minimally invasive treatment for craniosynostosis

    • Principal Investigator
      Nuri Takashi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Osaka Medical College
  •  The role of Shh in tongue development

    • Principal Investigator
      OKUHARA Shigeru
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Application of biomaterials for regulation of osteoblast differentiation to craniosynostosisPrincipal Investigator

    • Principal Investigator
      ISEKI Sachiko
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Plastic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Supramolecular scaffolds with molecular mobility for periodontal tissue regeneration

    • Principal Investigator
      YUI Nobuhiko
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Tokyo Medical and Dental University
  •  The development of minimally invasive bone regeneration strategy using neural crest-derived cells of hair follicles.

    • Principal Investigator
      Kamijo Ryutaro
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Shh signaling in pharyngeal development

    • Principal Investigator
      OKUHARA Shigeru
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Is epithelial-mesenchymal transition of stellate reticulum cells in enamel organ associated with induction of vasculogenesis?

    • Principal Investigator
      HARADA Hidemitsu
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Iwate Medical University
  •  Analysis of the role of Trxl and Txnip under the oxidative stress condition in periodontitis.

    • Principal Investigator
      EBE Noriko
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Periodontal dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  MFCS4 in palate development

    • Principal Investigator
      OKUHARA Shigeru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Epoch-making approach for tooth root regeneration using human iPS cells

    • Principal Investigator
      SUDA Naoto
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Meikai University
      Tokyo Medical and Dental University
  •  Involvement of sonic hedgehog signaling in secondary palate formationPrincipal Investigator

    • Principal Investigator
      ISEKI Sachiko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Studies of regenerative medicine on differentiation into hepatic and bile duct cells for preclinical trial to surgery

    • Principal Investigator
      TERAOKA Hirobumi, 寺本 研一
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Inhibitory regulation of osteogenesis in sutures of mammalian skullPrincipal Investigator

    • Principal Investigator
      ISEKI Sachiko
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  The better isolation and detection methods of cranial neural crest stem cells (CNCSC) and the therapeutic potentiality of CNCSC in the treatment of craniofacial abnormalities.

    • Principal Investigator
      ETO Kazuhiro
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of craniosynostosis caused by mutations in fibroblast growth factor receptors and their related genesPrincipal Investigator

    • Principal Investigator
      ISEKI Sachiko
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  頭蓋冠の骨形成過程におけるFGF受容体の相互作用Principal Investigator

    • Principal Investigator
      井関 祥子
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Investigation of organaizers in vertebrate craniofacial development

    • Principal Investigator
      ETO Kazuhiro
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University, Graduate School
  •  The establishment of a new type of long-term culture system in which the whole embryo cultu lowed by a mandibular organ culture.

    • Principal Investigator
      ETO Kazuhiro
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Tokyo Medical and Dental Univercity
  •  マウス胚発生過程における神経堤細胞の出現機構の解析Principal Investigator

    • Principal Investigator
      井関 祥子
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      The University of Tokushima

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 2005 2003 2002 2001 Other

All Journal Article Presentation Book Patent

  • [Book] 「マウス表現型解析」失敗しないステップ・バイ・ステップアプローチ 原題 Mouse Phenotypes-A Hand Book of Mutation Analysis-2006

    • Author(s)
      大内淑代, 井関祥子訳 Papaioannou VE, Behringer RR著
    • Total Pages
      289
    • Publisher
      メディカルサイエンスインターナショナル社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] Fibroblast growth factor signalling regulates the development of tooth root2024

    • Author(s)
      Jin Chengxue、Adachi Noritaka、Yoshimoto Yuki、Sasabuchi Aino、Kawashima Nobuyuki、Ota Masato S.、Iseki Sachiko
    • Journal Title

      Journal of Anatomy

      Volume: 244 Issue: 6 Pages: 1067-1077

    • DOI

      10.1111/joa.14014

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19613, KAKENHI-PROJECT-23K06316, KAKENHI-PROJECT-21H03098
  • [Journal Article] Cranial suture lineage and contributions to repair of the mouse skull2024

    • Author(s)
      Doro Daniel、Liu Annie、Lau Jia Shang、Rajendran Arun Kumar、Healy Christopher、Krstic Marko、Grigoriadis Agamemnon E.、Iseki Sachiko、Liu Karen J.
    • Journal Title

      Development

      Volume: 151 Issue: 3 Pages: 1-9

    • DOI

      10.1242/dev.202116

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19613
  • [Journal Article] Augmented effect of fibroblast growth factor 18 in bone morphogenetic protein 2-induced calvarial bone healing by activation of CCL2/CCR2 axis on M2 macrophage polarization2023

    • Author(s)
      Namangkalakul Worachat、Nagai Shigenori、Jin Chengxue、Nakahama Ken-ichi、Yoshimoto Yuki、Ueha Satoshi、Akiyoshi Kazunari、Matsushima Kouji、Nakashima Tomoki、Takechi Masaki、Iseki Sachiko
    • Journal Title

      Journal of Tissue Engineering

      Volume: 14 Pages: 1-19

    • DOI

      10.1177/20417314231187960

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19613, KAKENHI-PROJECT-23K06593, KAKENHI-PROJECT-21H03098
  • [Journal Article] Synchondrosis fusion contributes to the progression of postnatal craniofacial dysmorphology in syndromic craniosynostosis.2023

    • Author(s)
      Hoshino Y, Takechi M, Moazen M, Steacy M, Koyabu D, Furutera T, Ninomiya Y, Nuri T, Pauws E, Iseki S.
    • Journal Title

      J Anat

      Volume: 242 Issue: 3 Pages: 387-401

    • DOI

      10.1111/joa.13790

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03098, KAKENHI-PROJECT-18H02492, KAKENHI-PROJECT-21H02546
  • [Journal Article] Quantitative Morphologic Analysis of Cranial Vault in Twist1+/- Mice: Implications in Craniosynostosis.2022

    • Author(s)
      Nuri T., Ota M., Ueda K., Iseki S.
    • Journal Title

      Plast Reconstr Surg

      Volume: 149 Issue: 1 Pages: 28e-37e

    • DOI

      10.1097/prs.0000000000008665

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H03098
  • [Journal Article] Dlx5-augmentation in neural crest cells reveals early development and differentiation potential of mouse apical head mesenchyme2021

    • Author(s)
      Vu Tri H.、Takechi Masaki、Shimizu Miki、Kitazawa Taro、Higashiyama Hiroki、Iwase Akiyasu、Kurihara Hiroki、Iseki Sachiko
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 2092-2092

    • DOI

      10.1038/s41598-021-81434-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06821, KAKENHI-PROJECT-20K15858, KAKENHI-PUBLICLY-20H04858, KAKENHI-PROJECT-21H03098, KAKENHI-PROJECT-21K19519, KAKENHI-PROJECT-19H01048
  • [Journal Article] Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling2021

    • Author(s)
      Guo Long、(他19名)、Ikegawa Shiro
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 2046-2046

    • DOI

      10.1038/s41467-021-22340-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02932, KAKENHI-PROJECT-20H00551, KAKENHI-PROJECT-21H03098, KAKENHI-PROJECT-21K19554
  • [Journal Article] Cell lineage‐ and expression‐based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development2021

    • Author(s)
      Takenoshita Manami、Takechi Masaki、Vu Hoang Tri、Furutera Toshiko、Akagawa Chisaki、Namangkalakul Worachat、Aoto Kazushi、Kume Tsutomu、Miyashin Michiyo、Iwamoto Tsutomu、Iseki Sachiko
    • Journal Title

      Developmental Dynamics

      Volume: - Issue: 8 Pages: 1-10

    • DOI

      10.1002/dvdy.324

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06821, KAKENHI-PROJECT-20K07243, KAKENHI-PROJECT-19K22665, KAKENHI-PROJECT-18H02682, KAKENHI-PROJECT-17K08513, KAKENHI-PROJECT-21H03098
  • [Journal Article] Heterozygous mutation of the splicing factor Sf3b4 affects development of the axial skeleton and forebrain in mouse2020

    • Author(s)
      Yamada Takahiko、Takechi Masaki、Yokoyama Norisuke、Hiraoka Yuichi、Ishikubo Harumi、Usami Takako、Furutera Toshiko、Taga Yuki、Hirate Yoshikazu、Kanai‐Azuma Masami、Yoda Tetsuya、Ogawa‐Goto Kiyoko、Iseki Sachiko
    • Journal Title

      Developmental Dynamics

      Volume: 249 Issue: 5 Pages: 622-635

    • DOI

      10.1002/dvdy.148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06821, KAKENHI-PROJECT-18K19605, KAKENHI-PROJECT-17H04357
  • [Journal Article] Temporospatial sonic hedgehog signalling is essential for neural crest-dependent patterning of the intrinsic tongue musculature2019

    • Author(s)
      Okuhara Shigeru、Birjandi Anahid A.、Adel Al-Lami Hadeel、Sagai Tomoko、Amano Takanori、Shiroishi Toshihiko、Xavier Guilherme M.、Liu Karen J.、Cobourne Martyn T.、Iseki Sachiko
    • Journal Title

      Development

      Volume: 146 Issue: 21 Pages: 180075-180075

    • DOI

      10.1242/dev.180075

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10260, KAKENHI-PROJECT-17H04357
  • [Journal Article] Sulfonated Polyrotaxane Surfaces with Basic Fibroblast Growth Factor Alter the Osteogenic Potential of Human Mesenchymal Stem Cells in Short-Term Culture.2019

    • Author(s)
      Rajendran AK, Arisaka Y, Iseki S, Yui N.
    • Journal Title

      ACS Biomater. Sci. Eng.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04357
  • [Journal Article] Effects of mechanical force application on the developing root apex in rat maxillary molars.2019

    • Author(s)
      Zhao L, Matsumoto Y, Iseki Y, Ono T.
    • Journal Title

      Archives of Oral Biology

      Volume: 101 Pages: 64-76

    • DOI

      10.1016/j.archoralbio.2019.03.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K11344, KAKENHI-PROJECT-18K19605
  • [Journal Article] Sulfonated Polyrotaxane Surfaces with Basic Fibroblast Growth Factor Alter the Osteogenic Potential of Human Mesenchymal Stem Cells in Short-Term Culture2019

    • Author(s)
      Rajendran Arun Kumar、Arisaka Yoshinori、Iseki Sachiko、Yui Nobuhiko
    • Journal Title

      ACS Biomaterials Science & Engineering

      Volume: 印刷中 Issue: 11 Pages: 5652-5659

    • DOI

      10.1021/acsbiomaterials.8b01343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K16399, KAKENHI-PROJECT-16H01852
  • [Journal Article] The improvement of calvarial bone healing by durable nanogel-crosslinked materialsJ Biomater Sci Polym Ed2018

    • Author(s)
      Charoenlarp P, Rajendran AK, Fujihara R, Kojima T, Nakahama K, Sasaki Y, Akiyoshi K, Takechi M, Iseki S.
    • Journal Title

      J Biomater Sci Polym Ed

      Volume: 29 Issue: 15 Pages: 1876-1894

    • DOI

      10.1080/09205063.2018.1517403

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04357
  • [Journal Article] Transcription factor Foxc1 is involved in anterior part of cranial base formation.2018

    • Author(s)
      Mya N, Furutera T, Okuhara S, Kume T, Takechi M, Iseki S.
    • Journal Title

      Conget. Anom.

      Volume: - Issue: 5 Pages: 158-166

    • DOI

      10.1111/cga.12268

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04357, KAKENHI-PROJECT-16K11744
  • [Journal Article] Role of Fibroblast Growth Factors in bone regeneration.2017

    • Author(s)
      Charoenlarp P., Arun Kumar R., Iseki S.
    • Journal Title

      Inflammation and Regeneration

      Volume: 37 Issue: 1 Pages: 10-10

    • DOI

      10.1186/s41232-017-0043-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04357, KAKENHI-PROJECT-16K15746
  • [Journal Article] Foxc2-expressing cells during mouse organogenesis.2017

    • Author(s)
      Amin M.B., Miura M. Uddin M.K., Islam M.J., Yoshida N., Iseki S., Kume T. Trainor P.A., Saitsu H. Kazushi Aoto.
    • Journal Title

      Congenital Anomalies

      Volume: 57 Issue: 1 Pages: 24-31

    • DOI

      10.1111/cga.12198

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15746, KAKENHI-PROJECT-17H04357
  • [Journal Article] Injectable Shear-Thinning CaSO4/FGF-18-Incorporated Chitin-PLGA Hydrogel Enhances Bone Regeneration in Mice Cranial Bone Defect Model.2017

    • Author(s)
      Sivashanmugam A, Charoenlarp P, Deepthi S, Rajendran A, Nair SV, Iseki S, Jayakumar R.
    • Journal Title

      Injectable Shear-Thinning CaSO4/FGF-18-Incorporated Chitin-PLGA Hydrogel Enhances Bone Regeneration in Mice Cranial Bone Defect Model.

      Volume: 9 Issue: 49 Pages: 42639-42652

    • DOI

      10.1021/acsami.7b15845

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15746
  • [Journal Article] Intermediate phenotype between ADULT syndrome and EEC syndrome caused by R243Q mutation in TP63.2016

    • Author(s)
      Otsuki Y., Ueda K., Satoh C., Maekawa R., Yoshiura K., Iseki S.
    • Journal Title

      Plast Reconstr Surg Glob Open

      Volume: 4 Issue: 12 Pages: e1185-e1185

    • DOI

      10.1097/gox.0000000000001185

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15746
  • [Journal Article] Foxc1 is required for early stage telencephalic vascular development.2015

    • Author(s)
      Prasitsak T, Nandar M, Okuhara S, Ichinose S, Ota MS, Iseki S.
    • Journal Title

      Dev Dyn.

      Volume: 244 Issue: 5 Pages: 703-711

    • DOI

      10.1002/dvdy.24269

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670831, KAKENHI-PROJECT-25463130
  • [Journal Article] Effects of embryonic hypoxia on lip formation.2012

    • Author(s)
      Nagaoka R, Okuhara S, Sato Y, Amagasa T, Iseki S.
    • Journal Title

      Birth Defects Res A Clin Mol Teratol.

      Volume: 94(4) Issue: 4 Pages: 215-22

    • DOI

      10.1002/bdra.23000

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592254
  • [Journal Article] Disintegration of the medial epithelial seam:Is cell death important in palatogenesis?2011

    • Author(s)
      Iseki S.
    • Journal Title

      Dev. Growth Differ.

      Volume: 53(2) Pages: 259-268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592254
  • [Journal Article] Pocket epithelium in the pathological setting for HMGB1 release.2011

    • Author(s)
      Ebe N, Hara-Yokoyama M, Iwasaki K, Iseki S, Okuhara S, Podyma-Inoue KA, Terasawa K, Watanabe A, Akizuki T, Watanabe H, Yanagishita M,Izumi Y.
    • Journal Title

      J Dent Res.

      Volume: 90(2) Issue: 2 Pages: 235-40

    • DOI

      10.1177/0022034510385688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592254
  • [Journal Article] Disintegration of the medial epithelial seam : Is cell death important in palatogenesis?2011

    • Author(s)
      Iseki S.
    • Journal Title

      Dev.Growth Diff. 53,(2)

      Pages: 125-276

    • NAID

      10027900580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Journal Article] ADAMTSL6ss rescues fibrillin-1 microfibril disorder in Marfan syndrome mouse model through the promotion of fibrillin-1 assembly2011

    • Author(s)
      Saito M, Kurokawa M, Oda M, Oshima M, Tsutsui K, Kosaka K, Nakao K, Ogawa M, Manabe RI, Suda N, Ganjargal G, Hada Y, Noguchi T, Teranaka T, Sekiguchi K, Yoneda T, Tsuji T
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 9 Pages: 38602-13

    • DOI

      10.1002/jcp.24021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390546, KAKENHI-PROJECT-23390471, KAKENHI-PROJECT-23593018, KAKENHI-PROJECT-23659963, KAKENHI-PROJECT-23792418, KAKENHI-PROJECT-24659916, KAKENHI-PROJECT-24890063
  • [Journal Article] Disintegration of the medial epithelial seam : Is cell death important in palatogenesis2010

    • Author(s)
      Iseki S.
    • Journal Title

      Dev.Growth Differ.

      Volume: 53(2) Pages: 259-268

    • NAID

      10027900580

    • Data Source
      KAKENHI-PROJECT-20390510
  • [Journal Article] Runx1 and Runx2 cooperate during sternal morphgenesis.2010

    • Author(s)
      Kimura A., Inose H., Yano F., Fujita K., Ikeda T., Sato S., Iwasaki M., Jinno T., Ae K., Fukumoto S., Takeuchi Y., Itoh H., Imamura T., Kawaguchi H., Chung UI., Martin JF., Iseki S., Shinomiya K., Takeda S.
    • Journal Title

      Development. 137(7)

      Pages: 1159-1167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Journal Article] A novel method of mouse ex utero transplantation of hepatic progenitor cells into the fetal liver2009

    • Author(s)
      Shikanai M, Asahina K, Iseki S, Teramoto K, Nishida T, Saito T, Shimizu-Saito K, Ota M, Eto K, Teraoka H
    • Journal Title

      Biochemical and Biophysical Research Communications 381

      Pages: 276-282

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390343
  • [Journal Article] A novel method of mouse ex utero transplantation ofhepatic progenitor cells into the fetal liver.2009

    • Author(s)
      Shikanai M., Asahina K., Iseki S., Teramoto K., Nishida T., Shimizu-Saito K., Ota M., Eto K., Teraoka H.
    • Journal Title

      Biochem.Res.Commun. 381(2)

      Pages: 276-282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Journal Article] FGF9 monomer/dimer equilibrium regulates extracellular matrix affinity and tissue diffusion.2009

    • Author(s)
      Harada M., Murakami H., Okawa A., Okimoto N., Hiraoka S., Nakahara T., Akasaka R., Shiraishi Y., Futatsugi N., Mizutani-Koseki Y., Kuroiwa A., Shirouzu M., Yokoyama S., Taiji M., Iseki S., Ornitz D.M. Koseki H.
    • Journal Title

      Nat.Genet. 41(3)

      Pages: 289-298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Journal Article] Association of Tenascin-W expression with mineralization in mouse calvarial development.2009

    • Author(s)
      Mikura A., Okuhara S., Saito M., Ota M.,Ueda K., Iseki S.
    • Journal Title

      Congenit.Anom.(Kyoto) 49(2)

      Pages: 77-84

    • NAID

      10027388147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Journal Article] Twist inducereversal of myotube formation.2008

    • Author(s)
      Hjiantoniou E., Anayasa M., Nicolaou P., Bantounas I., Saito M., Iseki S., Uney J.B., Phylactou L.A.
    • Journal Title

      Differentiation 76

      Pages: 182-192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Journal Article] Impaired meningeal development in association with apical expansion of calvarial bone osteogenesis in the Foxcl mutant.2008

    • Author(s)
      Vivatbutsiri P., Ichinose S., Hytonen M., Sainio K., Eto K., Iseki S.
    • Journal Title

      J. Anat. 212

      Pages: 603-611

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Journal Article] Cell lineage in mammalian craniofacial mesenchyme.2008

    • Author(s)
      Yoshida T., Vivatbutsiri P., Morriss-Kay G., Saga Y., Iseki S.
    • Journal Title

      Mech.Dev. 125

      Pages: 797-808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Journal Article] Development and tissue origins of the mammalian cranial base.2008

    • Author(s)
      McBratney-Owen B., Iseki S., Bamforth S.D.Olsen B.R., Morriss-Kay G.M.
    • Journal Title

      Dev.Biol. 322

      Pages: 121-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Journal Article] Dual odontogenic origins develop at the early stage of rat maxillary incisor development.2006

    • Author(s)
      Kriangkrai R., Iseki S., Eto K., Chareonvit S.
    • Journal Title

      Anat.Emb. 211

      Pages: 101-108

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] Dual odontogenic origins develop at the early stage of rat maxillary incisor development.2006

    • Author(s)
      Kriangkrai R., Iseki S., Eto K., Chareonvit S.
    • Journal Title

      Anatomy and Embryology 211

      Pages: 101-108

    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] Study of Paxo mutant rat revealed the association between upper incisor formation and midface formation2006

    • Author(s)
      Kriangkrai R., Chareonvit S., Fujiwara M., Yahagi K., Eto K., Iseki S.
    • Journal Title

      Developmental Dynamics (in press)

    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] Study of Pax6 mutant rat revealed the association between upper incisor formation and midface formation2006

    • Author(s)
      Kriangkrai R., Chareonvit S., Fujiwara M., Yahagi K., Eto K., Iseki S.
    • Journal Title

      Dev.Dyn. 235

      Pages: 2134-2143

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] Twist is involved in establishment of the coronal suture.2005

    • Author(s)
      Yoshida T., Phylactou L.A., Uney J.B., Ishikawa I., Eto K., Iseki S.
    • Journal Title

      J.Anat. 206

      Pages: 437-444

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] Twist is involved in establishment of the coronal suture.2005

    • Author(s)
      Yoshida T., Phylactou L.A., Uney J.B., Ishikawa I., Eto K., Iseki S.
    • Journal Title

      J.Anat. in press

    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] Assessing adenoviral hammerhead ribozyme and shRNA casettes in neurons : Ihibition of endogenous Caspase-3 activity and protection from apoptotic cell death.2005

    • Author(s)
      Bantoumas I., Glover C.P.J., Kelly S., Iseki S., Phylactou L.A., Uney J.B.
    • Journal Title

      J.Neurosci.Res. 79

      Pages: 661-669

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] Assessing adenoviral hammerhead ribozyme and shRNA casettes in neurons : Ihibition of endogenous Caspase-3 activity and protection from apoptotic cell death.2005

    • Author(s)
      Bantounas I., Glover C.P.J., Kelly S., Iseki S., Phylactou L.A., Uney J.B.
    • Journal Title

      J.Neurosci.Res. 79

      Pages: 661-669

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] Assessing adenoviral hammerhead ribozyme and shRNA cassettes in neurons : Inhibition of endogenous Caspase-3 activity and protection from apoptotic cell death.2005

    • Author(s)
      Bantounas I., Glover C.P.J., Kelly S., Iseki S., Phylactou L.A., Uney J.B.
    • Journal Title

      J.Neurosci.Res. in press

    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] 形態学的タンパク質解析のテクノロジー:免疫染色法入門2005

    • Author(s)
      井関 祥子
    • Journal Title

      バイオテクノロジージャーナル(羊土社) 5巻4号

    • Data Source
      KAKENHI-PROJECT-15390554
  • [Journal Article] DNazyme-mediated cleavage of Twist transcripts and increase in cellular apoptosis.2003

    • Author(s)
      Hjiantoniou E., Iseki S., Uney J.B., Phylactou L.A.
    • Journal Title

      Biochem.Biophys.Res.Commun. 300

      Pages: 178-181

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357015
  • [Journal Article] Disappearance of epidermal growth factor receptor is essential in the fusion of the nasal epithelium.2003

    • Author(s)
      Fujino M., Osumi N., Ninomiya Y., Iseki S., Shibasaki Y., Eto K.
    • Journal Title

      Anat.Sci.Int. 78(1)

      Pages: 25-35

    • NAID

      50000771412

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357015
  • [Journal Article] Tissue origins and interactions in the mammalian skull vault.2002

    • Author(s)
      Jiang X., Iseki S., Maxson R.E., Sucov H.M., Morriss-Kay G.M.
    • Journal Title

      Dev.Biol. 241

      Pages: 106-116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357015
  • [Journal Article] Synergistic effect of fibroblast growth factor-4 in ectopic bone formation induced by bone morphogenetic protein-2.2002

    • Author(s)
      Kubota K, Iseki S, Kuroda S, Oida S, Iimura T, Duarte WR, Ohya K, Ishikawa I, Kasugai S.
    • Journal Title

      Bone 31

      Pages: 465-471

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357015
  • [Journal Article] Study of Fibroblast Growth Factor Receptor Signaling during Skull Vault Development by Ex-Utero Surgery.2001

    • Author(s)
      Iseki S., Morriss-Kay G.M., Eto K.
    • Journal Title

      J.Hard Tissue Biology 10

      Pages: 25-29

    • NAID

      110001142353

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357015
  • [Journal Article] Genetic control of the cell pro-liferation-differentiation balance in the developing skull vault : roles of fibroblast growth factor receptor signaling pathways.2001

    • Author(s)
      Morriss-Kay G.M., Iseki S., Johnson D.
    • Journal Title

      The Molecular Basis of Skeletogenesis (ed.J.Goode) Novartis Fund Symp. 232

      Pages: 102-116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357015
  • [Journal Article] Effects of the curly tail genotype on neuroepithelial integrity and cell proliferation during late stages of primary neurulation.2001

    • Author(s)
      Hall M., Gofflot F., Iseki S., Morriss-Kay G.M.
    • Journal Title

      J.Anat 199

      Pages: 645-655

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357015
  • [Journal Article] Twist is involved in establishment of the coronal suture.

    • Author(s)
      Yoshida T., Phylactou LA., Uney JB., Ishikawa I., Eto K., Iseki S.
    • Journal Title

      J.Anatomy In press

    • Data Source
      KAKENHI-PROJECT-13357015
  • [Patent] 歯根形成促進剤および歯根形成促進方法2007

    • Inventor(s)
      太田正人, 川島伸之, 中原貴, 井関祥子
    • Industrial Property Rights Holder
      東京医科歯科大学
    • Filing Date
      2007-02-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390554
  • [Patent] 歯根形成促進剤及び歯根形成促進方法2006

    • Inventor(s)
      井関 祥子, 太田 正人, 川島 伸之, 中原 貴
    • Industrial Property Rights Holder
      東京医科歯科大学
    • Filing Date
      2006-03-01
    • Data Source
      KAKENHI-PROJECT-15390554
  • [Presentation] FGF18シグナルによる歯根形成の制御2023

    • Author(s)
      金 成学, 吉本 由紀井関 祥子
    • Organizer
      第41回日本骨代謝学会
    • Data Source
      KAKENHI-PROJECT-22K19613
  • [Presentation] FGF18シグナルによる歯根形成の制御2023

    • Author(s)
      金 成学, 吉本 由紀、井関 祥子
    • Organizer
      第41回日本骨代謝学会
    • Data Source
      KAKENHI-PROJECT-21H03098
  • [Presentation] 鰓弓と咽頭の形成-表情筋発生の細胞系譜解析からみえてきた哺乳類頭部形成-2023

    • Author(s)
      足立礼孝, Robert G. Kelly, 井関祥子
    • Organizer
      第63回日本先天異常学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K06316
  • [Presentation] Fibroblast growth factor signaling regulates the development of tooth root2023

    • Author(s)
      Chengxue Jin, Noritaka Adachi, Yuki Yoshimoto, Nobuyuki Kawashima, Masato S. Ota, Sachiko Iseki
    • Organizer
      第88回口腔病学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K06316
  • [Presentation] 頭蓋冠を形成する細胞の多様性2023

    • Author(s)
      吉本由紀、金成学、足立礼孝、中濱健一、井関祥子
    • Organizer
      第128回日本解剖学会総会・全国学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K19613
  • [Presentation] Foxc1欠失マウスの胎生期水頭症で認められた終脳底部の異常血管網形成におけるMMP9の蓄積2023

    • Author(s)
      笹淵愛乃、吉本由紀、Thanit Prasitsak、足立礼孝、久米努、大隅典子、井関祥子
    • Organizer
      第63回日本先天異常学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H03098
  • [Presentation] FGF18シグナルは歯根形成を制御する2023

    • Author(s)
      金成学, 足立礼孝, 吉本由紀, 川島伸之, 太田 正人, 井関 祥子
    • Organizer
      第65回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K06316
  • [Presentation] FGF18シグナルは歯根形成を制御する2023

    • Author(s)
      金 成学, 足立 礼孝, 吉本 由紀, 川島 伸之, 太田 正人, 井関 祥子
    • Organizer
      第65回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-22K19613
  • [Presentation] 鰓弓と咽頭の形成ー表情筋発生の細胞系譜解析からみえてきた哺乳類頭部形成ー2023

    • Author(s)
      足立礼孝、Robert G. Kelly、井関祥子
    • Organizer
      第63回日本先天異常学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K19613
  • [Presentation] Foxc1欠失マウスの胎生期水頭症で認められた終脳底部の異常血管網形成におけるMMP9の蓄積2023

    • Author(s)
      笹笹淵愛乃、吉本由紀、Thanit Prasitsak、足立礼孝、久米努、大隅典子、井関祥子
    • Organizer
      第63会日本先天異常学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K19613
  • [Presentation] FGF18 modulates M2-like macrophage polarizationby inducing CCL2-CCR2 signaling in calvarial bone healing2022

    • Author(s)
      Worachat Namangkalakul, Shigenori Nagai, Ken-ichi Nakahama, Chengxue Jin, Satoshi Ueha, Kazunari Akiyoshi, Kouji Matsushima, Masaki Takechi and Sachiko Iseki
    • Organizer
      Gordon Research Conference -Craniofacial Morphogenesis and Tissue Regeneration-
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03098
  • [Presentation] Craniosynostosisの発症メカニズム2022

    • Author(s)
      井関祥子
    • Organizer
      第65回日本形成外科学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H03098
  • [Presentation] Ontogenic trajectories of cranial growth in syndromic craniosynostosis mouse models2021

    • Author(s)
      Masaki Takechi, Yukiko Hoshino, Mehran Moazen, Daisuke Koyabu, Sachiko Iseki
    • Organizer
      第44回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H03098
  • [Presentation] Effects of Indirect Activity of Fibroblast Growth Factor 18 on M2-like Macrophage Polarization in Calvarial Bone Healing2021

    • Author(s)
      Worachat Namangkalakul, Shigenori Nagai, Ken-ichi Nakahama, Kazunari Akiyoshi, Masaki Takechi, Sachiko Iseki
    • Organizer
      第42回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-21H03098
  • [Presentation] 頭蓋縫合早期癒合症モデルマウスの成長に伴う頭蓋形態変化の定量的解析2021

    • Author(s)
      星野裕紀子、武智正樹、Mehran Moazen、小薮大輔、井関祥子
    • Organizer
      第81回日本先天異常学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H03098
  • [Presentation] Ontogenic trajectories of cranial growth in syndromic craniosynostosis mouse models2021

    • Author(s)
      Yukiko Hoshino, Masaki Takechi, Mehran Moazen, Daisuke Koyabu, Toshiko Furutera, Youichiro Ninomiya, Erwin Pauws6, Takashi Nuri, Sachiko Iseki
    • Organizer
      2nd Advances in Craniosynostosis Basic Science to Clinical Practice
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03098
  • [Presentation] uCTを活用した疾患モデルマウスの頭部形態の解析例2020

    • Author(s)
      武智正樹, 山田隆彦, 星野裕紀子, 竹内理華, 井関祥子
    • Organizer
      . 日本先天異常学会第60回学術集会(シンポジウム講演:Web開催)
    • Data Source
      KAKENHI-PROJECT-18K06821
  • [Presentation] Cell lineage- and expression-based inference of molecular function of fork head box transcription factor Foxc2 in craniofacial development2019

    • Author(s)
      Manami Takeoshita, Masaki Takechi, Kazushi Aoto, Tsutomu Kume, Michiyo Miyashin, Sachiko Iseki
    • Organizer
      4th Meeting of the International Association for Dental Research Asia Pacific Region
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19605
  • [Presentation] 頭蓋縫合早期癒合症患者由来骨芽細胞および骨芽細胞由来iPS細胞の再分化過程における関連遺伝子発現パターンの検討2019

    • Author(s)
      井関祥子、武智正樹、Rajendran Arun Kumar、原田浩之、柳澤昇平、上田晃一
    • Organizer
      第42回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04357
  • [Presentation] Cell lineage- and expression-based inference of molecular function of fork head box transcription factor Foxc2 in craniofacial development2019

    • Author(s)
      Manami Takeoshita, Masaki Takechi, Kazushi Aoto, Tsutomu Kume, Michiyo Miyashin, Sachiko Iseki
    • Organizer
      4th Meeting of the International Association for Dental Research Asia Pacific Region 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04357
  • [Presentation] Apert症候群患者頭蓋骨由来骨芽細胞における分化マーカーの発現検討2019

    • Author(s)
      柳澤 昇平、武智正樹、Rajendran Arun Kumar、上田晃一、塗隆志、要匡、柳 久美子、小林眞司、 原田敦子、原田浩之、井関祥子
    • Organizer
      第15回 Craniosynostosis研究会
    • Data Source
      KAKENHI-PROJECT-17H04357
  • [Presentation] Dlx5-augmentation in neural crest cells induces ectopic calvarial cartilages.2019

    • Author(s)
      Tri Vu Hoang, Masaki Takechi, Miki Shimizu, Taro Kitazawa, Hiroki Higashiyama, Akiyasu Iwase, Hiroki Kurihara, Sachiko Iseki
    • Organizer
      第59回日本先天異常学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19605
  • [Presentation] Dlx5-augmentation in neural crest cells induces ectopic calvarial cartilages.2019

    • Author(s)
      Tri Vu Hoang, Masaki Takechi, Miki Shimizu, Taro Kitazawa, Hiroki Higashiyama, Akiyasu Iwase, Hiroki Kurihara, Sachiko Iseki
    • Organizer
      第59回日本先天異常学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04357
  • [Presentation] 口蓋上皮 TGF-β および Shh は,口蓋間葉の Tenascin C 発現を誘導する2018

    • Author(s)
      大木 調,岡 暁子,緒方佳代子,中村 雅子,奥原 滋,尾崎 正雄,井関 祥子,阪井 丘芳
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K11744
  • [Presentation] Polyrotaxane surfaces for regulating osteogenic differentiation2018

    • Author(s)
      Rajendran ArunKumar, 有坂慶紀, 由井伸彦, 井関祥子
    • Organizer
      第40回日本バイオマテリアル学会大会
    • Data Source
      KAKENHI-PROJECT-16H01852
  • [Presentation] Using Biomaterials for bone repair and regeneration2018

    • Author(s)
      Sachiko Iseki
    • Organizer
      The 6th Tripartite Conference on Tooth and Bone in Development & Regeneration
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04357
  • [Presentation] Nager症候群の発生学的成因の解明に向けて2018

    • Author(s)
      山田隆彦, 横山紀典, 平岡優一, 石久保春美, 宇佐美貴子, 多賀祐喜, 柳久美子, 後藤希代子, 要匡, 武智正樹, 井関祥子
    • Organizer
      日本先天異常学会
    • Data Source
      KAKENHI-PROJECT-18K06821
  • [Presentation] ポリロタキサンの分子運動性を利用した骨分化制御2018

    • Author(s)
      Rajendran Arun Kumar, 有坂慶紀, 由井伸彦, 井関祥子
    • Organizer
      第39回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-16H01852
  • [Presentation] Polyrotaxanes for the purpose of regulating osteogenic differentiation2018

    • Author(s)
      Arun Kumar Rajendran, Yoshinori Arisaka, Nobuhiko Yui, Sachiko Iseki
    • Organizer
      日本バイオマテリアル学会
    • Data Source
      KAKENHI-PROJECT-17H04357
  • [Presentation] Regulation of osteogenic differentiation by utilizing molecular mobility of polyrotaxanes.2018

    • Author(s)
      Arun Kumar Rajendran, Yoshinori Arisaka, Nobuhiko Yui, Sachiko Iseki
    • Organizer
      日本炎症再生学会
    • Data Source
      KAKENHI-PROJECT-17H04357
  • [Presentation] Application of biomaterials in osteogenesis2017

    • Author(s)
      Sachiko Iseki
    • Organizer
      The 6 Asian Biomaterials Congress along with APSAO 2017 meeting & 27th National Conference of SBAOI
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15746
  • [Presentation] Regulation of Osteogenic Differentiation by Utilizing Supramolecular Mobility of Polyrotaxanes for the Treatment of Craniosynostosis.2017

    • Author(s)
      Rajendran AK, Arisaka Y, Yui N, Iseki S.
    • Organizer
      第13回Craniosynostosis研究会
    • Data Source
      KAKENHI-PROJECT-16K15746
  • [Presentation] RGD含有多孔性NanoClikハイブリッドゲルを利用した頭蓋冠骨修復2016

    • Author(s)
      Pornkawee Charoenlarpa, Rie Fujiharab, Yoshihiro Sasakib, Kazunari Akiyoshib, c, Sachiko Iseki
    • Organizer
      日本炎症・再生医学会
    • Place of Presentation
      京都勧業会館「みやこめっせ」京都
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-16K15746
  • [Presentation] Shh signaling during patterning of the murine tongue2016

    • Author(s)
      Shigeru OKUHARA, Tomoko Sagai, Anahid A. Birjandi2Hadeel Al-Lami, Tomoko Sagai, Takanori Amano, Toshihiko Shiroishi, Karen Liu, Martyn T. Cobourne, Sachiko Iseki
    • Organizer
      JSDB Special Symposium: Frontier of Developmental Biology
    • Place of Presentation
      東京大学小柴ホール(東京都・文京区)
    • Data Source
      KAKENHI-PROJECT-16K11744
  • [Presentation] MFCS4はShhとSox9を介して咽頭諸器官の発生を制御する2015

    • Author(s)
      奥原 滋、濱崎 七海、嵯峨井 知子、天野 孝紀、大内 淑代、城石 俊彦、井関 祥子
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25463130
  • [Presentation] 舌の形態形成異常に起因する口蓋裂モデルマウスの解析2013

    • Author(s)
      奥原滋、町田章彦 、天野孝紀 、嵯峨井知子、 城石俊彦、井関祥子
    • Organizer
      第53回日本先天異常学会学術集会
    • Place of Presentation
      吹田 大阪千里ライフサイエンスセンター
    • Data Source
      KAKENHI-PROJECT-25463130
  • [Presentation] Tongue and palate development in Shh-/+MFCS4+/-2012

    • Author(s)
      Shigeru OKUHARA, Ryosuke NAGAOKA, Takanori AMANO, Tomoko SAGAI, Toshihiko SHIROISHI, Sachiko ISEKI
    • Organizer
      Joint Meeting of The 45th Annual Meeting of the Japanese Society of Developmental Biologists & The 64th Annual Meeting of the Japan Society for Cell Biology
    • Place of Presentation
      神戸
    • Year and Date
      2012-05-28
    • Data Source
      KAKENHI-PROJECT-22592254
  • [Presentation] Tongue development in Shh-/+MFCS4+/-.2012

    • Author(s)
      Shigeru OKUHARA, Ryosuke NAGAOKA,Takanori AMANO, Tomoko SAGAI, ToshihikoSHIROISHI, Sachiko ISEKI
    • Organizer
      Gordon Research Conference Craniofacial Morphogenesis & Tissue Regeneration
    • Place of Presentation
      Ventura, CA, USA
    • Year and Date
      2012-03-18
    • Data Source
      KAKENHI-PROJECT-22592254
  • [Presentation] Osteoblastic differentiation of transgenic mice overexpressing Apert syndrome-type mutant FGFR2 and its soluble form2010

    • Author(s)
      Suzuki H, Suda N, Shiga M, Nakamura M, Iseki S, Moriyama K
    • Organizer
      10th Tooth morphogenesis and differentiation
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-21390546
  • [Presentation] Cleft palate in mice of sonic hedgehog and its cis-regulatory region MF CS4 compound heterozygote2010

    • Author(s)
      Okuhara S, Sagai T, Nagaoka R Amano T, Shiroishi T, Iseki S
    • Organizer
      43^<rd> Annual Meeting for Japanese Society of Developmental Scientists
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Effects of embryonic hypoxia on maxillofacial development2010

    • Author(s)
      Nagaoka R, Okuhara S, Amagasa T, Iseki S
    • Organizer
      The 16th International Society of Differntiation Conference
    • Place of Presentation
      Nara, Japan
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Osteoblastic differentiation of transgenic mice overexpressing Apert syndrome-type mutant FGFR2 and its solubleform.2010

    • Author(s)
      鈴木尋之, 須田直人, 志賀百年., 谷本幸穂, 中村正孝, 井関祥子, 森山啓司
    • Organizer
      The 10th Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Berlin
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Effects of embryonic hypoxia maxillofacial development.2010

    • Author(s)
      Nagaoka R., Okuhara S., Amagasa T., Iseki S.
    • Organizer
      The 16th International Society of Differentiation Conference
    • Place of Presentation
      Nara
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Cleft palate in compound heterozygote of sonic hedgehog and MFCS42010

    • Author(s)
      Okuhara S, Sagai T, Nagaoka R, Amano T, Shiroishi T, Iseki S
    • Organizer
      The 16th International Society of Differntiation Conference
    • Place of Presentation
      Nara, Japan
    • Data Source
      KAKENHI-PROJECT-22592254
  • [Presentation] FGFシグナルの胎児マウス頭蓋冠骨芽細胞分化に与える影響2010

    • Author(s)
      永山友子、中原貴、太田正人、春日井昇平、井関祥子
    • Organizer
      第30回日本炎症・再生医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Cleft palate in compound heterozygote of sonic hedgehog and MFCS42010

    • Author(s)
      Okuhara S, Sagai T, Nagaoka R Amano T, Shiroishi T, Iseki S
    • Organizer
      The 16th International Society of Differntiation Conference
    • Place of Presentation
      Nara, Japan
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Effects of embryonic hypoxia on maxillofacial development2010

    • Author(s)
      Nagaoka R, Okuhara S, Amagasa T, Iseki S
    • Organizer
      The 16th International Society of Differntiation Conference
    • Place of Presentation
      Nara, Japan
    • Data Source
      KAKENHI-PROJECT-22592254
  • [Presentation] Apert症候群型の変異FGFR2とその可溶性変異体を過剰発現するトランスジェニックマウスの解析2010

    • Author(s)
      鈴木尋之、須田直人、志賀百年、谷本幸穂、中村正孝、井関祥子、森山啓司
    • Organizer
      第69回日本矯正歯科学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Apert症候群型の変異FGFR2(S252W)とその可溶性変異体を過剰発現するトランスジェニックマウスの細胞生物学的解析2010

    • Author(s)
      鈴木尋之, 須田直人, 志賀百年, 谷本幸穂, 中村正孝, 井関祥子, 森山啓司
    • Organizer
      第69回日本矯正歯科学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21390546
  • [Presentation] 胎児期低酸素状態が顔面形成に与える影響2010

    • Author(s)
      長岡亮介、奥原滋、天笠光雄、井関祥子
    • Organizer
      第50回日本先天異常学会学術集会
    • Place of Presentation
      淡路市
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Cleft palate in mice of sonic hedgehog and its cis-regulatory region MFCS4 compound heterozygote2010

    • Author(s)
      Okuhara S, Sagai T, Nagaoka R, Amano T, Shiroishi T, Iseki S
    • Organizer
      43^<rd> Annual Meeting for Japanese Society of Developmental Scientists
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-22592254
  • [Presentation] 胎児期低酸素状態が顔面形成に与える影響2010

    • Author(s)
      長岡亮介、奥原滋、天笠光雄、井関祥子
    • Organizer
      第50回日本先天異常学会学術集会
    • Place of Presentation
      淡路市
    • Data Source
      KAKENHI-PROJECT-22592254
  • [Presentation] Cleft palate in compound heterozygote of sonic hedgehog and MFCS42010

    • Author(s)
      Okuhara S., Sagai T., Nagaoka R., Amano T., Shiroishi T., Iseki S.
    • Organizer
      The 16th International Society of Differentiation Conference
    • Place of Presentation
      Nara
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] FGF18-induced osteoblast differentiation in developing mouse fetal calvaria.2009

    • Author(s)
      井関祥子, 中原貴, 太田正人
    • Organizer
      The 26th NAITO Conference on Osteobiology
    • Place of Presentation
      Awaji Hyogo, Japan
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] FGFR2IIIc-S252W及びSoluble form of FGFR2IIIc-S252Wトランスジェニックマウスを用いた頭蓋骨骨芽細胞の分化制御の検討2009

    • Author(s)
      鈴木尋之、須田直人、井関祥子、森山啓司
    • Organizer
      第27回日本骨代謝学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Twist reverses muscle cell differentiation.2009

    • Author(s)
      Nikolaos M., Mustafa A., Antonis, A., Iseki S., Uney J., Phylactou L.
    • Organizer
      Molecular and Cellular basis of Regeneration and Repair, EMBO Conference Series
    • Place of Presentation
      Sesimbra, Portugal
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Involvement of Foxcl in blood vessel formation of craniofacial region.2009

    • Author(s)
      Iseki S., Vivatbutsiri P., Okuhara S.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Involvement of cis-regulatory element of sonic hedgehog in palatal development.2009

    • Author(s)
      Okuhara S., Sagai T., Shiroishi T., Iseki S.
    • Organizer
      16th International Society of Developmental Biologists Congress
    • Place of Presentation
      Edinburgh, England
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] FGF18 enhances osteogenesis of mouse fetal skull bone.Gordon Research Conference2009

    • Author(s)
      永山友子, 中原貴, 太田正人, 井関祥子
    • Organizer
      Fibroblast Growth Factors in Development & Disease
    • Place of Presentation
      Ventura, California, USA
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Impaired meningeal development is associated with defects in skull bone development in the Foxc1 mutant mouse.2008

    • Author(s)
      Iseki S., Ichinose S., Vivatbutsiri P.
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] tenascin-Nの骨芽細胞分化への関与2008

    • Author(s)
      奥原滋、斎藤正寛、太田正人、井関祥子
    • Organizer
      第50回歯科基礎医学会学術大会ならびに総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Saethre-Chotzen症候群モデルマウスにおける頭蓋骨の成長2008

    • Author(s)
      塗隆志、上田晃一、井関祥子、太田正人、大場創介、奥原滋、三倉文子
    • Organizer
      第17回日本形成外科学会基礎学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Impaired meningeal development is associated with defects in skull bone development.2008

    • Author(s)
      Iseki S., Ichinose S., Vivatbutsiri P.
    • Organizer
      第48回日本先天異常学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390510
  • [Presentation] Shh in tongue development

    • Author(s)
      Shigeru OKUHARA, Sachiko ISEKI
    • Organizer
      第56回歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25463130
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