TAKAHASHI Hiroki 高橋宏樹

… Alternative Names

高橋広樹タカハシヒロキ

Less

Researcher Number	80256403
External Links
Affiliation (based on the past Project Information) *help	2010 – 2012: 東京慈恵会医科大学, 医学部, 講師 2003 – 2004: Jikei University School of Medicine, Lecturer, 医学部, 講師 1994 – 2003: 東京慈恵会医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 自己免疫性肝炎 / NKT / CDR3領域 / REGURATORY CELL / LIVER / ORAL TOLERANCE / 肝内樹状細胞 / 肝内類洞内皮細胞 / IL-10・IL-12 / アポトーシス … More / 活性化リンパ球 / 肝内免疫環境 / 経口寛容誘導 / 調節性細胞 / 経口寛容 / 肝免疫 / TOLERANCE / AUTOIMMUNE HEPATITIS / Vα24JαQ / CDLd / CD1b / CD1d / Vα24 / 原発性胆汁性肝改変 / DAMP受容体 / CD8細胞 / CD4細胞 / 制御性T細胞 / NKT細胞 / インスリン抵抗性 / DAMP / NKT2細胞 / TCRVβ鎖 / 肝内浸潤T細胞 / 原発性胆汁性肝硬変 / TCRレパトア / 肝疾患 / LFA-1 / 可溶性ICAM-1 … More Except Principal Investigator 自己免疫性肝炎 / 原発性胆汁性肝硬変 / PBC / IFN-γ / CTLA-4 / 樹状細胞 / AIH / IL-12 / 動物モデル / Autoimmune Hepatitis / Th1 / FDC / CD5 / Regulatory cell / Dendritic cell / Animal Model / PDC-E2 / 調節性細胞 / DC / 自己抗原 / 胆管細胞 / 実験モデル / POLYMORPHISM / PEC / 疾患感受性遺伝子 / 遺伝子多型 / DENDRITIC CELL / ANIMAL MODEL / AUTOIMMUNE HEPATITIS / 細胞障害性T細胞 / 実験的自己免疫性肝炎 / 融合細胞 / 肝癌細胞 / DR4 / CD25 / HLA-DR4 / 肝内T細胞浸潤 / 融合樹状細胞 / animal model / Cre-loxP transgenic mouse / asialoglycoprotein receptor / 遺伝子導入 / 抗アシアログリコプロテインレセプター抗体 / 肝特異抗原 / CD80 / Th2サイトカイン / Th1サイトカイン / ステロイド / 再燃 / トランスジェニックマウス / アシアログリコプロテインレセプター / Vbeta7 / TCR reperatoire / Th2 balance / 細胞質内サイトカイン発現 / Th2プロフィール / 原発生胆汁性肝硬変 / Th2バランス / 慢性C型肝炎 / 肝内サイトカイン発現 / Vβ7 / TCRレパトア / Th_2バランス / Th_1 / soluble CD23 / B cell / Chronic hepatitis type C / Autoimmune hepatitis / IL-4 / 免疫グロブリン産生細胞 / 高γグロブリン血症 / CD23 / B細胞 / C型慢性肝炎 / heparin / antisulfatide antibody / endothelial cell antibody / hepatic sinusoidal endothelial cell / autoimmune hepatitis / 肝類洞内皮細胞 / 自己抗体 / 内皮細胞 / 類洞内皮細胞 / 類洞壁内皮細胞 / ヘパリン / スルファチド / 内皮細胞抗体 / 類洞壁内原細胞 Less

The participation of NKT2 cell and insulin resistance in the pathogenesis of autoimmune hepatitis.Principal Investigator
- Principal Investigator
  
  TAKAHASHI Hiroki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine
ANALYSIS OF THE PATHOGENESIS OF PRIMARY BILIARY CIRRHOSIS BY USING ANIMAL MODEL THAT IS ESTABLISHED BY MULTI STEP BREAKING OF TOLERANCE
- Principal Investigator
  
  ZENIYA Mikio
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDICINE
THE ROLE OF THE LIVER FOR THE INDUCTION OF ORAL TOLERANCE.Principal Investigator
- Principal Investigator
  
  TAKAHASHI Hiroki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine
IDENTIFICATION OF NEW NON-HLA DISEASE SUESEPUTABILITY GENE OF AUTOIMMUNE HEPATITIS
- Principal Investigator
  
  WATANABE Fumitoki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDCINE
ESTABLISHMENT OF AUTOIMMUNE HEPATITIS MODEL BY USING FUSION CELL OF HEPATOCYTE AND DENDRITIC CELL.
- Principal Investigator
  
  ZENIYA Mikio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine
PRESENTATION OF SULFACHID ANTIGEN BY INTRAHEPATIC CD1b POSITIVE ANTIGEN PRESENTING CELL OF AUTOIMMUNE HEPATITIS.Principal Investigator
- Principal Investigator
  
  TAKAHASHI Hiroki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDCINE
MOCECULAR MECHANISMS OF HEPATOCYTOTOXICITY IN AUTOIMMUNE LIVER DISEASES
- Principal Investigator
  
  ZENIYA Mikio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The JIKEI University School of Medicine
MOLECULAR MECHANISMS OF HEPATOCYTOTOXICITY IN AUTOIMMUNE LIVER DISEASES
- Principal Investigator
  
  AIZAWA Yoshio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The JIKEI University School of Medicine
原発性胆汁性肝硬変のペプチド療法を目的とした肝内浸潤TCRβ鎖CDR3領域の解析Principal Investigator
- Principal Investigator
  
  高橋宏樹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine
自己免疫性肝炎の免疫応答を規定する肝内浸潤T細胞受容体β鎖CDR領域の解析Principal Investigator
- Principal Investigator
  
  高橋広樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine
Mechanism of hepatocyte injury in autoimmune hepatitis : involvement of hepatic sinusoidal endothelial cell injury.
- Principal Investigator
  
  TODA Gotaro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The Jikei University School of Medicine
B cell activation in autoimmune hepatitis and chronic hepatitis type C in relation to pathophysiology of the disease
- Principal Investigator
  
  AIZAWA Yoshio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The Jikei University School of Medicine
肝疾患における血中可溶性接着分子の産生機序とその機能の解析Principal Investigator
- Principal Investigator
  
  高橋宏樹
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine

All 2013 2012 2011 2010 Other

All Journal Article Presentation Other

[Journal Article] Characteristics of autoimmune hepatitis in the Asia-Pacific Region: historical review2012
- Author(s)
  Zeniya M. Takahashi H
- Journal Title
  
  Hepatol Int
  
  Volume: 6 Issue: 1 Pages: 342-349
- DOI
  10.1007/s12072-011-9313-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748
[Journal Article] Intrahepatic activated NKT cell has a significant role to exacerbate the hepatitis in experimental autoimmune hepatitis model2012
- Author(s)
  Nakano M Takahashi Het al.(他6名)
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: 170 Issue: 3 Pages: 274-282
- DOI
  10.1111/j.1365-2249.2012.04664.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748, KAKENHI-PROJECT-24501334
[Journal Article] Characteristics of autoimmune hepatitis in the Asia-Pacific Region : historical review2012
- Author(s)
  Zeniya M, Takahashi H
- Journal Title
  
  Hepatol Int
  
  Volume: 6 Pages: 342-349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748
[Journal Article] Acute presentation of autoimmune hepatitis: Does it exist? A published work review2011
- Author(s)
  Takahashi H, Zeniya M
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Issue: 6 Pages: 498-504
- DOI
  10.1111/j.1872-034x.2011.00808.x
- NAID
  10031144117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748
[Journal Article] 自己免疫性肝炎の診断におけるスコアリングシステムの位置付け2011
- Author(s)
  高橋宏樹銭谷幹男
- Journal Title
  
  日本消化器病学会誌
  
  Volume: 108 Pages: 1938-1844
- NAID
  10030298660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748
[Journal Article] Acute presentation of autoimmune hepatitis : Does it exist? A published work review2011
- Author(s)
  Takahashi H, Zeniya M
- Journal Title
  
  Hepatol Res.
  
  Volume: 41 Pages: 498-504
- NAID
  10031144117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748
[Journal Article] A short version of a HRQoL questionnaire for Italian and Japanese patients with Primary Biliary Cirrhosis.2010
- Author(s)
  Montali L, Tanaka A, Riva P, Takahashi H, et al.
- Journal Title
  
  Dig Liver Dis.
  
  Volume: 47 Pages: 718-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748
[Journal Article] Siginicance of interferon-βfor the treatment of hepatitis C virus infection in hemodialyzed patients.2010
- Author(s)
  Zeniya M. Takahashi H. et al. (他8名)
- Journal Title
  
  Hepatol Res
  
  Volume: 40 Issue: 9 Pages: 852-869
- DOI
  10.1111/j.1872-034x.2010.00693.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748
[Journal Article] Accumulation of functional regulatory T cells in actively inflamed liver in mouse dendritic cell-based autoimmune hepatic inflammation Clin Immunol2010
- Author(s)
  Saeki C. Takahashi H. et al. (他4名)
- Journal Title
  
  Clinical Immunology
  
  Volume: 135 Issue: 1 Pages: 155-165
- DOI
  10.1016/j.clim.2009.12.002
- ISSN
  1521-6616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748
[Journal Article] Natural killer cells target HCV core proteins during the innate immune response in HCV transgenic mice.2010
- Author(s)
  Satoh K, Takahashi H, Matsuda C, Tanaka T, Miyasaka M, Zeniya M, Kohara M.
- Journal Title
  
  J Med Virol
  
  Volume: 82 Issue: 9 Pages: 1545-1553
- DOI
  10.1002/jmv.21859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590440, KAKENHI-PROJECT-22590748
[Journal Article] Accumulation of functional regulatory T cells in actively inflamed liver in mouse dendritic cell-based autoimmune hepatic inflammation2010
- Author(s)
  Saeki C.Takahashi H., et al.
- Journal Title
  
  Clin Immunol
  
  Volume: 135 Pages: 155-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748
[Journal Article] Significance of interferon-β for the treatment of hepatitis C virus infection in hemodialyzed patients.2010
- Author(s)
  Zeniya M.Takahashi H., et al.
- Journal Title
  
  Hepatol Res.
  
  Volume: 40 Pages: 852-869
- NAID
  10026696686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎軽症例の臨床像と治療2013
- Author(s)
  高橋宏樹他
- Organizer
  2013 日本消化器病学会総会
- Place of Presentation
  鹿児島
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] ステロイド治療抵抗性自己免疫性肝炎例の臨床像の検討2012
- Author(s)
  高橋宏樹他
- Organizer
  2012 J-DDW 日本肝臓学会大会
- Place of Presentation
  神戸
- Year and Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] microRNAs of CD4+ T cells are associated with immunological proses in primary biliary cirrhosis.2012
- Author(s)
  Nakagawa R Takahashi Het al.
- Organizer
  2012 AASLD Annual Meeting
- Place of Presentation
  Boston MA USA
- Year and Date
  2012-11-07
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] High levels of microRNA-155 in CD4+T cells participate in the Th1 response and accumulation of intrahepatic regulatory T cells in autoimmune hepatitis.2012
- Author(s)
  Saeki C Takahashi Het al.
- Organizer
  2012 AASLD Annual Meeting
- Place of Presentation
  Boston MA USA
- Year and Date
  2012-11-07
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎における性差の検討:男性症例は注意深く治療、経過観察する必要がある2012
- Author(s)
  高橋宏樹他
- Organizer
  2012 日本肝臓学会総会
- Place of Presentation
  金沢
- Year and Date
  2012-06-04
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎の肝内miRNA発現プロファイルと病態との関連の解析2012
- Author(s)
  佐伯千里高橋宏樹他
- Organizer
  2012 日本肝臓学会総会
- Place of Presentation
  金沢
- Year and Date
  2012-06-04
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] ウルソデオキシコール酸単独治療が奏効した自己免疫性肝炎症例の臨床像の検討2012
- Author(s)
  鳥巣勇一高橋宏樹他
- Organizer
  2012 日本肝臓学会総会
- Place of Presentation
  金沢
- Year and Date
  2012-06-04
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎の臨床像、治療反応性に発症年齢が及ぼす影響の検討2012
- Author(s)
  中野真範高橋宏樹他
- Organizer
  2012 日本肝臓学会総会
- Place of Presentation
  金沢
- Year and Date
  2012-06-04
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] Interactions among liver infiltrated CTL, Treg and NKT cell from spleen participated in the pathogenesis of experimental autoimmune hepatitis.2012
- Author(s)
  Takahashi Het al.
- Organizer
  2012 EASL Annual Meeting
- Place of Presentation
  Barcerona Spein
- Year and Date
  2012-04-21
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎の病態形成への肝内NKT細胞の関与2011
- Author(s)
  中野真範高橋宏樹他
- Organizer
  2011日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-07
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] Antinuclear antibody screening in AIH should be performed by indirect fluorescent immunoassay but not by enzyme-linked immunosorbent assay2011
- Author(s)
  Takahashi Het al.
- Organizer
  2011 AASLD Annual Meeting
- Place of Presentation
  San Francisco CA USA
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝疾患におけるB細胞のサイトカイン産生動態と病態との関連2011
- Author(s)
  高橋宏樹他
- Organizer
  2011 日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝傷害を惹起する自己反応性CD8+T細胞の活性化と肝内誘導には肝内活性化NKT細胞が関与する2011
- Author(s)
  中野真範高橋宏樹他
- Organizer
  2011 日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎の病態形成と自己反応性T細胞、NKT細胞、制御性T細胞の動態の関連2011
- Author(s)
  高橋宏樹、佐伯千里他
- Organizer
  2011 J-DDW 日本肝臓学会大会
- Place of Presentation
  福岡
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] Activated NKT cells potentiate cytotoxic T cell-mediated autoimmune hepatic inflammation2011
- Author(s)
  Nakano M Takahashi Het al.
- Organizer
  2011 AASLD Annual Meeting
- Place of Presentation
  San Francisco CA USA
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] Insulin resistance was involved in the pathogenesis of autoimmune hepatitis without the relation to prednisone therapy2010
- Author(s)
  Takahashi H, et al.
- Organizer
  60th Annual Meeting of the American Association for the Study of Liver Disease
- Place of Presentation
  Boston MA.USA
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝疾患におけるインスリン抵抗性、血中アデイポカインの動態と病態との関連2010
- Author(s)
  高橋宏樹, 他
- Organizer
  第46回日本肝臓学会総会ワークショップ
- Place of Presentation
  山形、日本
- Year and Date
  2010-05-30
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] Insulin resistance was involved in the pathogenesis of autoimmune hepatitis without the relation to prednisone therapy.2010
- Author(s)
  Takahashi Het al.
- Organizer
  2010 AASLD Annual Meeting
- Place of Presentation
  Boston MA USA
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎の診断におけるスコアリング、抗核抗体測定に関する検討2010
- Author(s)
  高橋宏樹, 他
- Organizer
  第52回日本消化器病学会大会シンポジウム
- Place of Presentation
  横浜、日本
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎軽症例の臨床像と治療
- Author(s)
  高橋宏樹　他
- Organizer
  2013　日本消化器病学会総会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] ステロイド治療抵抗性自己免疫性肝炎例の臨床像の検討
- Author(s)
  高橋宏樹　他
- Organizer
  2012　日本肝臓学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] Interactions among liver infiltrated CTL, Treg and NKT cell from spleen participated in the pathogenesis of experimental autoimmune hepatitis
- Author(s)
  Takahashi H et al.
- Organizer
  2012 EASL Annual Meeting
- Place of Presentation
  Barcerona Spein
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] ウルソデオキシコール酸単独治療が奏効した自己免疫性肝炎症例の臨床像の検討
- Author(s)
  鳥巣勇一　高橋宏樹　他
- Organizer
  2012　日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] High levels of microRNA-155 in CD4＋T cells participate in the Th1 response and accumulation of
- Author(s)
  Saeki C Takahashi H et al.
- Organizer
  2012 AASLD Annual Meeting
- Place of Presentation
  Boston MA USA
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] microRNAs of CD4+ T cells are associated with immunological proses in primary biliary cirrhosis
- Author(s)
  Nakagawa R Takahashi H et al.
- Organizer
  2012 AASLD Annual Meeting
- Place of Presentation
  Boston MA USA
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎における性差の検討：男性症例は注意深く治療、経過観察する必要がある
- Author(s)
  高橋宏樹　他
- Organizer
  2012　日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎の肝内miRNA発現プロファイルと病態との関連の解析
- Author(s)
  佐伯千里　高橋宏樹　他
- Organizer
  2012　日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 他の自己免疫疾患を合併した自己免疫性肝炎症例の臨床像の検討
- Author(s)
  中川良　高橋宏樹　他
- Organizer
  2012　日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590748
[Presentation] 自己免疫性肝炎の臨床像、治療反応性に発症年齢が及ぼす影響の検討
- Author(s)
  中野真範　高橋宏樹　他
- Organizer
  2012　日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590748
[]

1. ZENIYA Mikio (70138767)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. TODA Gotaro (40090500)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. AIZAWA Yoshio (90147273)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. WATANABE Fumitoki (90231711)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. ISHIKAWA Tomohisa (10260944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUKADA Hiroyuki (60287282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 林昭太 (80287276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田中稔之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAHASHI Hiroki 高橋 宏樹

高橋 広樹 タカハシ ヒロキ

Research Projects

Research Products

Co-Researchers

The participation of NKT2 cell and insulin resistance in the pathogenesis of autoimmune hepatitis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ANALYSIS OF THE PATHOGENESIS OF PRIMARY BILIARY CIRRHOSIS BY USING ANIMAL MODEL THAT IS ESTABLISHED BY MULTI STEP BREAKING OF TOLERANCE

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

THE ROLE OF THE LIVER FOR THE INDUCTION OF ORAL TOLERANCE.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IDENTIFICATION OF NEW NON-HLA DISEASE SUESEPUTABILITY GENE OF AUTOIMMUNE HEPATITIS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ESTABLISHMENT OF AUTOIMMUNE HEPATITIS MODEL BY USING FUSION CELL OF HEPATOCYTE AND DENDRITIC CELL.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PRESENTATION OF SULFACHID ANTIGEN BY INTRAHEPATIC CD1b POSITIVE ANTIGEN PRESENTING CELL OF AUTOIMMUNE HEPATITIS.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MOCECULAR MECHANISMS OF HEPATOCYTOTOXICITY IN AUTOIMMUNE LIVER DISEASES

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MOLECULAR MECHANISMS OF HEPATOCYTOTOXICITY IN AUTOIMMUNE LIVER DISEASES

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

原発性胆汁性肝硬変のペプチド療法を目的とした肝内浸潤TCRβ鎖CDR3領域の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

自己免疫性肝炎の免疫応答を規定する肝内浸潤T細胞受容体β鎖CDR領域の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of hepatocyte injury in autoimmune hepatitis : involvement of hepatic sinusoidal endothelial cell injury.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

B cell activation in autoimmune hepatitis and chronic hepatitis type C in relation to pathophysiology of the disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肝疾患における血中可溶性接着分子の産生機序とその機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

TAKAHASHI Hiroki 高橋宏樹

高橋広樹タカハシヒロキ