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TAKENAGA Keizo  竹永 啓三

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… Alternative Names

竹永 啓三  タケナガ ケイゾウ

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Researcher Number 80260256
Other IDs
Affiliation (Current) 2026: 千葉県がんセンター(研究所), がんゲノムセンター がん先進治療開発研究室, 特任研究員
2026: 千葉県がんセンター(研究所), がん治療開発グループ がん先進治療開発研究室, 特任研究員
2026: 千葉県がんセンター(研究所), がん遺伝創薬研究室, 特任研究員
Affiliation (based on the past Project Information) *help 2024: 千葉県がんセンター(研究所), がんゲノムセンター がん先進治療開発研究室, 特任研究員
2023: 千葉県がんセンター(研究所), がん治療開発グループ がん先進治療開発研究室, 特任研究員
2022: 千葉県がんセンター(研究所), がん先進治療開発研究室, 特任研究員
2018 – 2021: 千葉県がんセンター(研究所), がん遺伝創薬研究室, 特任研究員
2008 – 2017: Shimane University, 医学部, 准教授 … More
2011: 島根大学, 医学部・生命科学講座腫瘍生物学, 准教授
2006 – 2007: 千葉県がんセンター(研究所), 化学療法研究部, 研究員
2005: Chiba Cancer Center Research Institute, Division of Chemotherapy, Senior Investigator, 化学療法研究部, 主席研究員
2004 – 2005: 千葉県がんセンター, 化学療法研究部, 主席研究員
2003: 千葉県がんセンター(研究所), 化学療法研究部, 主席研究員
2003: Chiba Cancer Center Research Institute, Division of Chemotherapy, Chief Scientist, 化学療法研究部, 主席研究員
2002: 千葉県がんセンター, 化学療法研究部, 主席研究員
1998 – 1999: 千葉県がんセンター, 研究局・化学療法研究部, 研究員
1998: Division of Chemotherapy, Chiba Cancer Center, Chief Scientist, 化学療法部, 研究員
1997: 千葉県がんセンター, 医学療法部, 研究員
1996: 千葉県がんセンター, 研究局, 研究員
1995: 千葉がん研, 化学療法研究部, 研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Digestive surgery / General medical chemistry / Pathological medical chemistry / Tumor biology / Biological Sciences / Cerebral neurosurgery
Except Principal Investigator
Basic Section 48040:Medical biochemistry-related / Basic Section 49010:Pathological biochemistry-related / Anesthesiology … More / Cerebral neurosurgery / Cerebral neurosurgery / Digestive surgery / Pathological medical chemistry / Thoracic surgery Less
Keywords
Principal Investigator
低酸素 / 膵臓がん / 腫瘍増殖 / 癌 / Hypoxia / HIF-1 / 転移 / ミトコンドリアDNA / 腫瘍内微小環境 / 細胞死 … More / IL-33 / 腫瘍微小環境 / 好中球 / CXCL3 / アディポネクチン / 皮下移植 / マウス膵臓がん細胞株 / sST2 / 病因生変異 / マイトファジー / ミトコンドリア / トンネルナノチューブ / 細胞間移行 / 細胞外小胞 / 前2型糖尿病 / アゴニスト / アディポネクチン受容体 / 抗糖尿病薬 / 肥満 / 糖尿病 / 膵癌 / AdipoRon / Cancer stem cell / Tissue・Cell / Cancer / がん幹細胞 / 組織・細胞 / Translesional DNA polymerase / Mutation / DNA polymerase ι / 不忠実DNA polymerase / 突然変異 / 腫瘍 / 寄生性代謝 / 活性酸素種 / 変異 / グルコース代謝 / エネルギー代謝 / 乳酸トランスポーター / ATP / 寄生性がん代謝 / 肺がん / 病因性変異 / がん微小環境 / 悪性度進展 / グルコース飢餓 / ST2L / アストロサイ / アストロサイト / 微小環境 / 薬剤抵抗性 / 脳腫瘍 … More
Except Principal Investigator
遺伝子治療 / Glioma / gene therapy / 低酸素 / 自殺遺伝子 / p53 / CArG element / Egr-1 / mtDNA / mtDNA変異 / 転移能 / 肺癌 / 転写活性 / VEGF / ミッドカイン / プロモーター / cytokine / サイトカイン / 癌 / 細胞間移行 / ミトコンドリアDNA / 転移 / 浸潤 / mt細胞間移行 / 変異mtDNA / がん増殖抑制 / TPP / PIポリアミド / malignancy / cancer / mutated mtDNA / Triphenylphosphonium / PI polyamide / SNP / 子宮癌 / 病原性mtDNA変異 / 子宮がん / 肺がん / PIP-TPP / 酸素代謝 / 細胞外酸性化速度 / 酸素消費量 / 麻酔薬 / ミトコンドリアサイブリッド細胞 / 電子伝達系 / プロポフォール注入症候群 / 細胞死 / サイブリッド / ミトコンドリア / プロポフォール / hypoxia sensitive promoter / radiation sensitive promoter / high-LET carbon ions / p53遺伝子 / 重粒子線治療 / 低酸素増感プロモーター / 放射線増感プロモーター / 重粒子線 / グリオーマ / Suicide gene / Radio-sensitization / glioma / 放射線増感 / retrovirus / gastrointestinal cancer / helper T cells / tumor immunology / レトロウイルス / 消化器がん / ヘルパーT細胞 / 腫瘍免疫 / ヒト腫瘍 / 変異 / 神経膠芽腫 / 癌部と非癌部 / 肺癌・大腸癌 / ROS / ラマンバンド / 髄液播種 / 神経膠腫 / 転移巣 / 原発巣 / 大腸癌 / HIF阻害 / HIF阻害剤 / 脱分化 / NCX / 腫瘍細胞 / hematopoietic reconstitution / SCID-hu / Stem Cells / Gene Therapy / SCID Less
  • Research Projects

    (20 results)
  • Research Products

    (137 results)
  • Co-Researchers

    (26 People)
  •  Analysis of the role of mtDNA mutations in invasion and metastasis using mitochondrial intercellular transfer

    • Principal Investigator
      越川 信子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  膵臓がんの同所及び異所性腫瘍微小環境内IL-33応答が腫瘍増殖に及ぼす影響の解析Principal Investigator

    • Principal Investigator
      竹永 啓三
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Tumor growth suppression by PIP targeting against mutated mtDNAs

    • Principal Investigator
      Koshikawa Nobuko
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Analysis of the mechanism of enhancement of metastasis by pathogenic mitochondrial DNA mutation.Principal Investigator

    • Principal Investigator
      TAKENAGA Keizo
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Effect of AdipoRon on the growth of pancreatic cancer cells in primary culture and obese prediabetic mice.Principal Investigator

    • Principal Investigator
      Takenaga Keizo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Center (Research Institute)
      Shimane University
  •  Investigation of the molecular mechanisms of propofol toxiciy by using mitochondria cybrids

    • Principal Investigator
      HIROTA Kiichi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Anesthesiology
    • Research Institution
      Kansai Medical University
  •  Analysis and regulation of parasitic metabolism by cancer cells harboring pathogenic mitochondrial DNA mutationPrincipal Investigator

    • Principal Investigator
      Takenaga Keizo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Shimane University
  •  がん微小環境におけるILー33/ST2L発現と悪性度進展への影響の解析Principal Investigator

    • Principal Investigator
      竹永 啓三
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Shimane University
  •  Comparison of the frequency of mtDNA mutation in primary and metastatic lesions of human malignant tumors

    • Principal Investigator
      KOSHIKAWA Nobuko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Analysis of the effects of tumor microenvironment on the susceptibility of malignant tumors to anticancer drugs-its therapeutic applicationPrincipal Investigator

    • Principal Investigator
      TAKENAGA Keizo
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Shimane University
  •  Effect of HIF inhibitors on tumor hypoxia-induced dedifferentiation and metastasis of lung carcinoma cells

    • Principal Investigator
      KOSHIKAWA Nobuko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Analysis of the effects of tumor hypoxia on dynamics of cancer stem cellsPrincipal Investigator

    • Principal Investigator
      KEIZO Takenaga
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Biological role of the regulation of the expressions of transpersonal DNA polymereases by hypoxiaPrincipal Investigator

    • Principal Investigator
      TAKENAGA Keizo
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Chiba Cancer Center Research Institute
  •  Cell-cidal effect of the combination therapy of p53 gene under the control of radiation- and hypoxia-sensitized promoter and heavy particle irradiation in glioma

    • Principal Investigator
      KOSHIKAWA Nobuko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Chiba cancer center research institute
  •  Combination of radiation and suicide gene therapy with radio-sensitized promoter/Endotherial precursor cell in glioma

    • Principal Investigator
      OGA Masaru
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Chiba Cancer Center Research Institute
  •  腫瘍で高発現を示す遺伝子のプロモーター領域を応用した自殺遺伝子治療

    • Principal Investigator
      田川 雅敏
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  腫瘍において高発現をみる遺伝子のプロモーターを用いた自殺遺伝子治療の基礎的検討

    • Principal Investigator
      田川 雅敏
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Immune gene therapy for gastrointestinal cancer by activation Th1-type helper T cells.

    • Principal Investigator
      TAGAWA Masatoshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Center Research Institute
  •  SCIDマウスを用いたサイトカイン遺伝子治療のin vivoモデルの確立

    • Principal Investigator
      田川 雅敏
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  ヒト腫瘍細胞・TILを用いたサイトカイン遺伝子治療のin vivoモデルの確立

    • Principal Investigator
      TAGAWA Masatoshi
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

  • [Journal Article] Suppression of NSCLC A549 tumor growth by a mtDNA mutation‐targeting pyrrole‐imidazole polyamide‐TPP and a senolytic drug2022

    • Author(s)
      Tsuji Kohei、Kida Yuki、Koshikawa Nobuko、Yamamoto Seigi、Shinozaki Yoshinao、Watanabe Takayoshi、Lin Jason、Nagase Hiroki、Takenaga Keizo
    • Journal Title

      Cancer Science

      Volume: - Issue: 4 Pages: 1321-1337

    • DOI

      10.1111/cas.15290

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03540, KAKENHI-PROJECT-19K07408, KAKENHI-PROJECT-20K07710, KAKENHI-PROJECT-19K07654, KAKENHI-PROJECT-22H04923
  • [Journal Article] Anticancer effect of a pyrrole‐imidazole polyamide‐triphenylphosphonium conjugate selectively targeting a common mitochondrial DNA cancer risk variant in cervical cancer cells2022

    • Author(s)
      Yao Jihang、Takenaga Keizo、Koshikawa Nobuko、Kida Yuki、Lin Jason、Watanabe Takayoshi、Maru Yoshiaki、Hippo Yoshitaka、Yamamoto Seigi、Zhu Yuyan、Nagase Hiroki
    • Journal Title

      International Journal of Cancer

      Volume: 152 Issue: 5 Pages: 962-976

    • DOI

      10.1002/ijc.34319

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08019, KAKENHI-PROJECT-21K09506, KAKENHI-PROJECT-19K07408, KAKENHI-PROJECT-19K07654, KAKENHI-PROJECT-20K07710, KAKENHI-PROJECT-21K14756, KAKENHI-PROJECT-22H04923
  • [Journal Article] Mitochondria: Endosymbiont bacteria DNA sequence as a target against cancer2021

    • Author(s)
      Nagase Hiroki、Watanabe Takayoshi、Koshikawa Nobuko、Yamamoto Seigi、Takenaga Keizo、Lin Jason
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 12 Pages: 4834-4843

    • DOI

      10.1111/cas.15143

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03540, KAKENHI-PROJECT-19K07408, KAKENHI-PROJECT-19K07654, KAKENHI-PROJECT-20K07710
  • [Journal Article] MCT4 is induced by metastasis-enhancing pathogenic mitochondrial NADH dehydrogenase gene mutations and can be a therapeutic target2021

    • Author(s)
      Takenaga Keizo、Koshikawa Nobuko、Akimoto Miho、Tatsumi Yasutoshi、Lin Jason、Itami Makiko、Nagase Hiroki
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 13302-13302

    • DOI

      10.1038/s41598-021-92772-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03540, KAKENHI-PROJECT-19K07408, KAKENHI-PROJECT-19K07673, KAKENHI-PROJECT-20K08199
  • [Journal Article] A PI polyamide-TPP conjugate targeting a mtDNA mutation induces cell death of cancer cells with the mutation2021

    • Author(s)
      N.Koshikawa N.Yasui Y.Kida Y.Shinozaki K.Tsuji T.Watanabe K.Takenag H.Nagase
    • Journal Title

      Cancer Science

      Volume: 未 Issue: 6 Pages: 1-9

    • DOI

      10.1111/cas.14912

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07408, KAKENHI-PROJECT-20K07710, KAKENHI-PROJECT-20H03540
  • [Journal Article] Intercellular transfer of mitochondrial DNA carrying metastasis-enhancing pathogenic mutations from high- to low-metastatic tumor cells and stromal cells via extracellular vesicles2021

    • Author(s)
      Takenaga Keizo、Koshikawa Nobuko、Nagase Hiroki
    • Journal Title

      BMC Molecular and Cell Biology

      Volume: 22 Issue: 1 Pages: 1-16

    • DOI

      10.1186/s12860-021-00391-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07408, KAKENHI-PROJECT-19K07654
  • [Journal Article] A linear five-ring pyrrole-imidazole polyamide-triphenylphosphonium conjugate targeting a mitochondrial DNA mutation efficiently induces apoptosis of HeLa cybrid cells carrying the mutation2021

    • Author(s)
      Koshikawa Nobuko、Kida Yuki、Yasui Nanami、Shinozaki Yoshinao、Tsuji Kohei、Watanabe Takayoshi、Lin Jason、Yamamoto Seigi、Takenaga Keizo、Nagase Hiroki
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 576 Pages: 93-99

    • DOI

      10.1016/j.bbrc.2021.08.088

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03540, KAKENHI-PROJECT-19K07408, KAKENHI-PROJECT-20K07710
  • [Journal Article] Role of the IL-33/ST2L axis in colorectal cancer progression2018

    • Author(s)
      Akimoto Miho、Takenaga Keizo
    • Journal Title

      Cellular Immunology

      Volume: - Pages: 103740-103740

    • DOI

      10.1016/j.cellimm.2017.12.014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-16K21177
  • [Journal Article] Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner2018

    • Author(s)
      Sumi Chisato、Okamoto Akihisa、Tanaka Hiromasa、Nishi Kenichiro、Kusunoki Munenori、Shoji Tomohiro、Uba Takeo、Matsuo Yoshiyuki、Adachi Takehiko、Hayashi Jun-Ichi、Takenaga Keizo、Hirota Kiichi
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 2 Pages: e0192796-e0192796

    • DOI

      10.1371/journal.pone.0192796

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-16K10974, KAKENHI-PROJECT-16K10975, KAKENHI-PROJECT-15K10551, KAKENHI-PROJECT-16K15682, KAKENHI-PROJECT-18K08877, KAKENHI-PROJECT-18K16501
  • [Journal Article] Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis.2018

    • Author(s)
      17.Akimoto M, Maruyama R, Kawabata Y, Tajima Y, Takenaga K.
    • Journal Title

      Cell Death & Disease

      Volume: 9 Issue: 8 Pages: 804-804

    • DOI

      10.1038/s41419-018-0851-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K21177, KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-16K10595
  • [Journal Article] HIF-2α dictates the susceptibility of pancreatic cancer cells to TRAIL by regulating survivin expression2017

    • Author(s)
      Harashima Nanae、Takenaga Keizo、Akimoto Miho、Harada Mamoru
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 26 Pages: 42887-42900

    • DOI

      10.18632/oncotarget.17157

    • NAID

      120006532063

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-17K07217, KAKENHI-PROJECT-16K21177
  • [Journal Article] HIF-1-mediated suppression of mitochondria electron transport chain function confers resistance to lidocaine-induced cell death2017

    • Author(s)
      Okamoto Akihisa、Sumi Chisato、Tanaka Hiromasa、Kusunoki Munenori、Iwai Teppei、Nishi Kenichiro、Matsuo Yoshiyuki、Harada Hiroshi、Takenaga Keizo、Bono Hidemasa、Hirota Kiichi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 3816-3816

    • DOI

      10.1038/s41598-017-03980-7

    • NAID

      120006364104

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-16K10974, KAKENHI-PROJECT-16K10975, KAKENHI-PUBLICLY-16H01573, KAKENHI-PUBLICLY-16H01640, KAKENHI-PROJECT-17H04261, KAKENHI-PROJECT-16K15576, KAKENHI-PROJECT-16K15682
  • [Journal Article] Cytoplasmic transfer of heritable elements other than mtDNA from SAMP1 mice into mouse tumor cells suppresses their ability to form tumors in C57BL6 mice2017

    • Author(s)
      Shimizu Akinori、Tani Haruna、Takibuchi Gaku、Ishikawa Kaori、Sakurazawa Ryota、Inoue Takafumi、Hashimoto Tetsuo、Nakada Kazuto、Takenaga Keizo、Hayashi Jun-Ichi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 493 Issue: 1 Pages: 252-257

    • DOI

      10.1016/j.bbrc.2017.09.035

    • NAID

      120007134703

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-16K18535
  • [Journal Article] Association of predicted pathogenic mutations in mitochondrial ND genes with distant metastasis in NSCLC and colon cancer2017

    • Author(s)
      Koshikawa Nobuko、Akimoto Miho、Hayashi Jun-Ichi、Nagase Hiroki、Takenaga Keizo
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 15535-15535

    • DOI

      10.1038/s41598-017-15592-2

    • NAID

      120007134603

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-16K21177, KAKENHI-PUBLICLY-16H01579, KAKENHI-PROJECT-16H02463, KAKENHI-PROJECT-17H03602
  • [Journal Article] The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells2016

    • Author(s)
      Okamoto A, Tanaka M, Sumi C, Oku K, Kusunoki M, Nishi K, Matsuo Y, Takenaga K, Shingu K, Hirota K
    • Journal Title

      BMC Anesthesiol

      Volume: 16 Issue: 1 Pages: 104-104

    • DOI

      10.1186/s12871-016-0273-3

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15577, KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-16K10974, KAKENHI-PROJECT-16K10975, KAKENHI-PROJECT-16K15682, KAKENHI-PROJECT-15K10551
  • [Journal Article] Soluble IL-33 receptor sST2 inhibits colorectal cancer malignant growth by modifying the tumour microenvironment.2016

    • Author(s)
      Akimoto M, Maruyama R, Takamaru H, Ochiya T, Takenaga K.
    • Journal Title

      Nat Commun.

      Volume: 7 Issue: 1 Pages: 13589-13589

    • DOI

      10.1038/ncomms13589

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-16K21177
  • [Journal Article] Interleukin-33 enhances programmed oncosis of ST2L-positive low-metastatic cells in the tumour microenvironment of lung cancer.2016

    • Author(s)
      Akimoto M, Hayashi JI, Nakae S, Saito H, Takenaga K.
    • Journal Title

      Cell Death Dis.

      Volume: 7 Issue: 1 Pages: e2057-e2057

    • DOI

      10.1038/cddis.2015.418

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25430110, KAKENHI-PROJECT-16H02463, KAKENHI-PROJECT-16K21177
  • [Journal Article] Efficient inhibition of tumor angiogenesis and growth by a synthetic peptide blocking S100A4-methionine aminopeptidase 2 interaction.2015

    • Author(s)
      Ochiya T, Takenaga K, Asagiri M, Nakano K, Satoh H, Watanabe T, Imajoh-Ohmi S, Endo H.
    • Journal Title

      Mol Ther Methods Clin Dev

      Volume: 2 Pages: 15008-15008

    • DOI

      10.1038/mtm.2015.8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Journal Article] Anticancer Effect of Ginger Extract Against Pancreatic Cancer Cells Mainly Through Reactive Oxygen Species-Mediated Autotic Cell Death.2015

    • Author(s)
      Akimoto M, Iizuka M, Kanematsu R, Yoshida M, Takenaga K.
    • Journal Title

      PLoS ONE

      Volume: 未定

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Journal Article] Anticancer Effect of Ginger Extract against Pancreatic Cancer Cells Mainly through Reactive Oxygen Species-Mediated Autotic Cell Death.2015

    • Author(s)
      Akimoto M, Iizuka M, Kanematsu R, Yoshida M, Takenaga K.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 5 Pages: e0126605-e0126605

    • DOI

      10.1371/journal.pone.0126605

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Journal Article] Silencing of S100A4, a metastasis-associated protein, in endothelial cells inhibits tumor angiogenesis and growth.2014

    • Author(s)
      Ochiya T, Takenaga K, Endo H.
    • Journal Title

      Angiogenesis

      Volume: 17 Issue: 1 Pages: 17-26

    • DOI

      10.1007/s10456-013-9372-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Journal Article] Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene.2014

    • Author(s)
      Shimizu A, Mito T, Hayashi C, Ogasawara E, Koba R, Negishi I, Takenaga K, Nakada K, Hayashi J
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 111 Issue: 8 Pages: 3104-3109

    • DOI

      10.1073/pnas.1318109111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240058, KAKENHI-PUBLICLY-24117503, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-25430110
  • [Journal Article] Specific mtDNA mutations in mouse carcinoma cells suppress their tumor formation via activation of the host innate immune system.2013

    • Author(s)
      Imanishi H, Takibuchi G, Kobayashi T, Ishikawa K, Nakada K, Mori M, Kikkawa Y, Takenaga K, Toyama-Sorimachi N, Hayashi J
    • Journal Title

      PLoS One

      Volume: 8 Issue: 9 Pages: e75981-e75981

    • DOI

      10.1371/journal.pone.0075981

    • NAID

      120007136806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240058, KAKENHI-PUBLICLY-24117503, KAKENHI-PROJECT-24500487, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-25430110, KAKENHI-PROJECT-25871165
  • [Journal Article] Polymorphic mutations in mouse mitochondrial DNA regulate a tumor phenotype.2013

    • Author(s)
      Takibuchi G, Imanishi H, Morimoto M, Ishikawa K, Nakada K, Toyama-Sorimachi N, Kikkawa Y, Takenaga K, Hayashi J
    • Journal Title

      Mitochondrion

      Volume: 13 Issue: 6 Pages: 881-887

    • DOI

      10.1016/j.mito.2013.07.117

    • NAID

      120007130592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240058, KAKENHI-PUBLICLY-24117503, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-25430110
  • [Journal Article] An inhibitor of HIF-α subunit expression suppresses hypoxia-induced dedifferentiation of human NSCLC into cancer stem cell-like cells2013

    • Author(s)
      Akimoto M, Nagasawa H, Hori H, Uto Y, Honma Y, Takenaga K.
    • Journal Title

      World J Med Genet

      Volume: 3(4) Issue: 4 Pages: 41-54

    • DOI

      10.5496/wjmg.v3.i4.41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791422, KAKENHI-PROJECT-25430110
  • [Journal Article] Angiogenic signaling aberrantly induced by tumor hypoxia.2011

    • Author(s)
      Takenaga K.
    • Journal Title

      Front Biosci. 16

      Pages: 31-48

    • Data Source
      KAKENHI-PROJECT-20591731
  • [Journal Article] MCL-1V, a novel mouse antiapoptotic MCL-l variant, generated by RNA splicing at a non-canonical splicing pair.2010

    • Author(s)
      Kojima S, Hyakutake A, Koshikawa N, Nakagawara A, Takenaga K
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 391 Pages: 492-497

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590349
  • [Journal Article] Reactive oxygen speciesgenerating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-1 alpha gene transcription via phosphatid ylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway2009

    • Author(s)
      Koshikawa N, Hayashi J, Nakagawara A, Takenaga K
    • Journal Title

      Journal of Biological Chemistry

      Volume: 284 Pages: 33185-33194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590349
  • [Journal Article] MCL-1V, a novel mouse antiapoptotic MCL-1 variant, generated by RNA splicing at a non-canonical splicing pair2009

    • Author(s)
      Kojima S, Hyakutake A, Koshikawa N, Nakagawara A, Takenaga K
    • Journal Title

      Biochem Biophys Res Common. 391

      Pages: 492-497

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590349
  • [Journal Article] Reactive oxygen species-generating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-lalpha gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway2009

    • Author(s)
      Koshikawa N, Hayashi J, Nakagawara A, Takenaga K
    • Journal Title

      Joarnal of Biological Chemistry 284

      Pages: 33185-33194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590349
  • [Journal Article] MCL-1V, a novel m ouse antiapoptotic MCL-1 variant, genera ted byRNA splicing at a non-canonical splicing pair2009

    • Author(s)
      Kojima S, Hyakutake A, Koshikawa N, Nakagawara A, Takenaga K
    • Journal Title

      Biochem BiophysRes Comun3

      Volume: 91 Pages: 492-497

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590349
  • [Journal Article] Reversible regulation of metastasis by ROS-generating mtDNA mutations2008

    • Author(s)
      Ishikawa K, Koshikawa N, Takenaga K, Nakada K, Hayashi J.
    • Journal Title

      Mitochondrion 8

      Pages: 339-344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591655
  • [Journal Article] Enhance glycolysis induced by mtDNA mutations does not regulate metastasis2008

    • Author(s)
      Ishikawa K, Hashizume O, Koshikawa N, Fukuda S, Nakada K, Takenaga K, Hayashi J.
    • Journal Title

      FEBS Letter 582

      Pages: 3525-3530

    • NAID

      120007138501

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591655
  • [Journal Article] ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis2008

    • Author(s)
      Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H,Nakada K, HonmaY, Hayashi J
    • Journal Title

      Science 320

      Pages: 661-664

    • NAID

      120007138465

    • Data Source
      KAKENHI-PROJECT-19591655
  • [Journal Article] Reversible re- gulation of metastasis by ROS- generating mtDNA mutations2008

    • Author(s)
      Ishikawa K, Koshikawa N, Takenaga K, Nakada K, Hayashi J
    • Journal Title

      Mito- chondrion, 8

      Pages: 339-344

    • Data Source
      KAKENHI-PROJECT-19591655
  • [Journal Article] Enhance glycolysis induced by mtDNA mutations does not regulate metastasis2008

    • Author(s)
      Ishikawa K, Hashizume O, Koshikawa N, Fukuda S, Nakada K, Takenaga K, Hayashi J
    • Journal Title

      FEBS Letter 582

      Pages: 3525-3530

    • NAID

      120007138501

    • Data Source
      KAKENHI-PROJECT-19591655
  • [Journal Article] HayashiJ-I. ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.2008

    • Author(s)
      Ishikawa K, Takenaga K. Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Honma Y
    • Journal Title

      Science 320

      Pages: 661-664

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Journal Article] ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis2008

    • Author(s)
      Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Honma Y, Hayashi J.
    • Journal Title

      Science 320

      Pages: 661-664

    • NAID

      120007138465

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591655
  • [Journal Article] ROS-generating mitochondrial KNA mutations can regulate tumor cell metastasis2008

    • Author(s)
      Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Honma Y, Hayashi J-I
    • Journal Title

      Science 320

      Pages: 661-664

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Journal Article] 3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositidr 3-kinases independently of autophagy inhibition.2007

    • Author(s)
      Ito S., Koshikawa N, Mochizuki S, Takenaga K
    • Journal Title

      Int. J. Oncology 31

      Pages: 261-268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Journal Article] 3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositidr 3-kinases independently of autophagy inhibition.2007

    • Author(s)
      Ito S., Koshikawa N, Mochizuki S, Takenaga K.
    • Journal Title

      Int. J. Oncology 31

      Pages: 261-268

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Journal Article] Sjoquist, Kozlova EN : Modified expression of S100A4/Mts1 protein in C6 glioma cells or surrounding astrocytes affects migration of tumor cells in vitro and in vivo.2007

    • Author(s)
      Takenaga K, Nygren J, Zelenina M, Ohira M, Iuchi T, Lukanidin E
    • Journal Title

      Neurobiol Dis. 25

      Pages: 455-463

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Journal Article] Modified expression of S100A4/Mts1 protein in C6 glioma cells or surrounding astrocytes affects migration of tumor cells in vitro and in vivo.2007

    • Author(s)
      Takenaga K, et. al.
    • Journal Title

      Neurobiol. Dis. 25

      Pages: 455-463

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Journal Article] Sensory neurite outgrowth on white matter astrocytes is influenced by intracellular and extracellular S100A4 protein.2006

    • Author(s)
      Fang Z, Forslund N, Takenaga K, et al.
    • Journal Title

      J Neurosci Res. (In press)

    • Data Source
      KAKENHI-PROJECT-16590257
  • [Journal Article] A procedure for culturing astrocytes from white matter and the application of the siRNA technique for silencing the expression of their specific marker, S100A4.2006

    • Author(s)
      EN.Kozlova, K.Takenaga.
    • Journal Title

      Brain Res Brain Res Protoc. 15

      Pages: 59-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591466
  • [Journal Article] Role of intracellular S 100A4 formigration of rat astrocytes.2006

    • Author(s)
      K.Takenaga, et al.
    • Journal Title

      Glia 53

      Pages: 313-321

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590257
  • [Journal Article] Intracellular calcium-binding protein S100A4 influences injury-induced migration of white matter astrocytes.2006

    • Author(s)
      Fang Z, Takenaga K, et al.
    • Journal Title

      Acta Neuropathol (Berl). (In press)

    • Data Source
      KAKENHI-PROJECT-16590257
  • [Journal Article] Role of intracellular S100A4 for migration of rat astrocytes.2006

    • Author(s)
      Takenaga K, Kozlova EN
    • Journal Title

      Glia 53

      Pages: 313-321

    • Data Source
      KAKENHI-PROJECT-16590257
  • [Journal Article] Role of intracellular S100A4 for migration of rat astrocytes.2006

    • Author(s)
      K.Takenaga
    • Journal Title

      Glia 53

      Pages: 313-321

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590257
  • [Journal Article] Hypoxia selects for high-metastatic Lewis lung carcinoma cells overexpressing Mcl-1 and exhibiting reduced apoptotic potential in solid tumors.2006

    • Author(s)
      Koshikawa N, Takenaga K. et al.
    • Journal Title

      Oncogene 25

      Pages: 917-928

    • Data Source
      KAKENHI-PROJECT-16590257
  • [Journal Article] Intracellular calcium-binding protein S100A4 influences injury-induced migration of white matter astrocytes.2006

    • Author(s)
      Z.Fang, N.Duthoit, G.Wicher, O.Kallskog, N.Ambartsumian, E Lukanidin, K.Takenaga, EN.Kozlova.
    • Journal Title

      Acta Neuropathol (Berl) 111

      Pages: 213-219

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591466
  • [Journal Article] Hypoxia-inducible factor-1 mediates the expression of DNA polymerase iota.2006

    • Author(s)
      Ito A, Koshikawa N, Mochizuki S, Omura K, Takenaga K
    • Journal Title

      Biochem. Biophys. Res. Commun. 351

      Pages: 306-311

    • Data Source
      KAKENHI-PROJECT-18590280
  • [Journal Article] Hypoxia selects for high-metastatic Lewis lung carcinoma cells overexpressing Mcl-1 and exhibiting reduced apoptotic potential in solid tumors.2006

    • Author(s)
      Koshikawa N, Maejima C, Miyazaki K, Nakagawara A, Takenaga K.
    • Journal Title

      Oncogene 25・6

      Pages: 917-928

    • Data Source
      KAKENHI-PROJECT-16591466
  • [Journal Article] Hypoxia-inducible factor-l mediates the expression of DNA polymerase2006

    • Author(s)
      Ito A, Koshikawa N, Mochizuki S., Omura K, Takenaga K.
    • Journal Title

      Biochem Biophys Res Commun 351

      Pages: 306-311

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Journal Article] Role of intracellular S100A4 for migration of rat astrocytes.2006

    • Author(s)
      K, Takenaga
    • Journal Title

      Glia 53

      Pages: 313-321

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591466
  • [Journal Article] Sensory neurite outgrowth on white matter astrocytes is influenced by intracellular and extracellular S100A4 protein.2006

    • Author(s)
      Z.Fang, N.Forslund, K.Takenaga, E.Lukanidin, EN.Kozlova.
    • Journal Title

      J Neurosci Res. 83

      Pages: 619-626

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591466
  • [Journal Article] Hypoxia selects for high-metastatic Lewis lung carcinoma cells overexpressing Mcl-1 and exhibiting reduced apoptotic potential in solid tumors.2006

    • Author(s)
      N.Koshikawa, C.Maejima, K.Miyazaki, A.Nakagawara, K.Takenaga.
    • Journal Title

      Oncogene. 25

      Pages: 917-928

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591466
  • [Journal Article] Role of intracellular S100A4 for migration of rat astrocytes.2006

    • Author(s)
      K.Takenaga, EN.Kozlova.
    • Journal Title

      Glia. 53

      Pages: 313-321

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591466
  • [Journal Article] Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-lalpha oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor.2005

    • Author(s)
      Koshikawa N, Takenaga K.
    • Journal Title

      Cancer Ressearch 65・24

      Pages: 11622-11630

    • Data Source
      KAKENHI-PROJECT-16591466
  • [Journal Article] Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-1 alpha oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor.2005

    • Author(s)
      N.Koshikawa, K.Takenaga.
    • Journal Title

      Cancer Research 65

      Pages: 11622-11630

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591466
  • [Journal Article] A Calcium binding protein, S100A4, mediates T cell dependent cytotoxicity as a transformation-associated antigen.2005

    • Author(s)
      N.Kondo, K.Takenaga, et al.
    • Journal Title

      Microbiol.Immunol. 49(1)

      Pages: 49-56

    • NAID

      10014377175

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591466
  • [Journal Article] A procedure for culturing astrocytes from white matter and the application of the siRNA technique for silencing the expression of their specific marker, S100A4.2005

    • Author(s)
      Kozlova EN, Takenaga K.
    • Journal Title

      Brain Res Brain Res Protoc. 15

      Pages: 59-65

    • Data Source
      KAKENHI-PROJECT-16590257
  • [Journal Article] Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-1 α oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor.2005

    • Author(s)
      Koshikawa N, Takenaga K.
    • Journal Title

      Cancer Res. 65

      Pages: 11622-11630

    • Data Source
      KAKENHI-PROJECT-16590257
  • [Journal Article] S100A4 inhibition by RNAi up-regulates osteoblast related genes in periodontal ligament cells.2005

    • Author(s)
      C.Kato, K.Takenaga, et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 326(1)

      Pages: 147-153

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591466
  • [Presentation] Hypoxia-induced downregulation of sST2 in CRC cells: its molecular mechanisms and potential as a therapeutic target.2024

    • Author(s)
      Miho Akimoto, Takao Susa, Noriyuki Okudaira, Nobuko Koshikawa, Harumi Hisaki, Masayoshi Iizuka, Keizo Takenaga, Mimi Tamamori-Adachi
    • Organizer
      The Eighth JCA-AACR Special Joint Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06644
  • [Presentation] マウス膵臓がん細胞におけるIL-33デコイ受容体sST2の発現低下は皮下腫瘍の増殖を促進する2024

    • Author(s)
      秋元 美穂、越川 信子、安達 三美、竹永 啓三
    • Organizer
      第83回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K06644
  • [Presentation] ミトコンドリアDNAバリアントががん細胞のミトコンドリア機能、浸潤能と薬剤感受性に及ぼす影響2024

    • Author(s)
      喬いく銘 越川信子 丸喜明 秋元美穂 高取敦志 竹永啓三
    • Organizer
      第83回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-24K10072
  • [Presentation] Growth inhibition of cancer cells by TPP-conjugated DNA gyrase inhibitors through suppression of mtDNA replication2023

    • Author(s)
      喬 昱銘、木田 裕貴、越川 信子、竹永 啓三
    • Organizer
      第36回国際哺乳類ゲノム会議
    • Data Source
      KAKENHI-PROJECT-19K07654
  • [Presentation] TPP結合DNAジャイレース阻害剤によるmtDNA複製阻害を介したがん細胞の増殖阻害2022

    • Author(s)
      喬 昱銘、木田 裕貴、越川 信子、竹永 啓三
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07654
  • [Presentation] DNAジャイレース阻害剤ーTPP複合体によるmtDNA複製阻害を介した癌細胞の細胞死の誘導2022

    • Author(s)
      喬いく銘、木田裕貴、越川信子、竹永啓三
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] 非小細胞肺癌を標的とした変異mtDNA標的PIP-TPPとBcl-xL阻害剤の併用療法の開発2021

    • Author(s)
      山本清義、越川信子、木田裕貴、渡部隆義、Lin Jason、竹永啓三、永瀬浩喜
    • Organizer
      先端モデル動物支援 若手支援技術講習会
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] 変異mtDNA標的PIP-TPPとBcl-xL阻害剤の併用による非小細胞肺癌A549腫瘍のSenotherapy2021

    • Author(s)
      山本清義、辻航平、越川信子、木田裕貴、渡辺隆義、リン ジェイソン、竹永啓三、永瀬浩喜
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] 変異mtDNA標的PIP-TPPとBcl-xL阻害剤の併用による非小細胞肺癌A549腫瘍のSenotherapy2021

    • Author(s)
      山本清義、越川信子、木田裕貴、渡部隆義、Lin Jason、竹永啓三、永瀬浩喜
    • Organizer
      第80回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] DNAジャイレース阻害剤ーTPP複合体によるmtDNA複製阻害を介した癌細胞のアポトーシスの誘導2021

    • Author(s)
      喬いく銘、木田裕貴、越川信子、竹永啓三、永瀬浩喜
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] ミトコンドリアDNA変異を標的にした薬剤候補によるがん細胞老化、細胞死、老化細胞除去誘導2020

    • Author(s)
      永瀬浩喜、越川信子、山本清義、辻航平、木田裕貴、竹永啓三
    • Organizer
      日本癌学会学術総会(第79回)
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] mtDNAを標的としたPIポリアミド-TPPによるA549肺がん細胞の細胞老化と老化細胞除去の誘導2020

    • Author(s)
      辻 航平、竹永 啓三、木田 裕貴、越川 信子、永瀬 浩喜
    • Organizer
      日本癌学会学術総会(第79回)
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] Retardation of Tumor cell growth by PI polyamide-drug conjugates targeting mtDNA mutation2019

    • Author(s)
      Nobuko Koshikawa, Kohei Tsuji, Keizo Takenaga, Hiroki Nagase
    • Organizer
      The 24th JFCR-ISCC Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] がん細胞が遊離する細胞外小胞にはミトコンドリアDNAが包含される2019

    • Author(s)
      竹永啓三、越川信子、永瀬浩喜
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07654
  • [Presentation] 細胞外小胞を介した細胞間ミトコンドリアDNA移行2019

    • Author(s)
      竹永啓三、越川信子、永瀬浩喜
    • Organizer
      第17回がんとハイポキシア研究会
    • Data Source
      KAKENHI-PROJECT-19K07654
  • [Presentation] 肺癌における転移促進性mtDNA ND遺伝子変異による乳酸トランスポーターMCT4の特異的発現促進2019

    • Author(s)
      竹永啓三、越川信子、永瀬浩喜
    • Organizer
      第28回日本癌病態治療研究会
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] 肺癌における転移促進性mtDNA ND遺伝子変異による乳酸トランスポーターMCT4の特異的発現促進2019

    • Author(s)
      越川信子、竹永啓三、永瀬浩喜
    • Organizer
      第78回日本癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] mtDNA変異を標的にした修飾PIポリアミドによるROS産生亢進と細胞増殖の抑制2019

    • Author(s)
      佐久間誠、辻航平、渡部隆義、越川信子、竹永啓三、永瀬浩喜
    • Organizer
      第78回日本癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] mtDNA変異を標的としたPyrrole-Imidazole-Polyamide修飾化合物による腫瘍増殖抑制効果の検討2019

    • Author(s)
      辻航平、越川信子、竹永啓三、永瀬浩喜
    • Organizer
      第42回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-19K07408
  • [Presentation] ヒト癌におけるミトコンドリアND遺伝子変異の病因性予測と遠隔転移との関連性の検討2017

    • Author(s)
      越川信子、秋元美穂、林純一、永瀬浩喜、竹永啓三
    • Organizer
      第15回がんとハイポキシア研究会
    • Data Source
      KAKENHI-PROJECT-16K10594
  • [Presentation] Reevaluation of association of mitochondrial ND gene pathogenic mutations with metastasis in NSCLC and colon cancer2017

    • Author(s)
      Koshikawa N, Akimoto M, Hayashi J, Nagase H, Takenaga K.
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K10594
  • [Presentation] AdipoRon induces cell death of pancreatic cancer cells through triggering Ca2+ uptake via mitochondrial Ca2+ uniporter2017

    • Author(s)
      Akimoto M, Takenaga K.
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K10594
  • [Presentation] 可溶性ST2は炎症性のがん微小環境を修飾し膵がん細胞の皮下増殖を抑制する2017

    • Author(s)
      秋元美穂、岡崎具樹、竹永啓三
    • Organizer
      第15回がんとハイポキシア研究会
    • Data Source
      KAKENHI-PROJECT-16K10594
  • [Presentation] 可溶性IL-33受容体sST2は大腸がん同所移植モデルにおいて腫瘍増殖および肝転移を抑制する2016

    • Author(s)
      秋元美穂、竹永啓三
    • Organizer
      第75回日本癌学会総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2016-10-08
    • Data Source
      KAKENHI-PROJECT-16K10594
  • [Presentation] mtDNA変異が制御する転移の予測因子としての乳酸トランスポーターMCT4の核局在2016

    • Author(s)
      越川信子、秋元美穂、植田健、飯笹俊彦、鍋谷圭宏、井内俊彦、永瀬浩喜、竹永啓三
    • Organizer
      第75回日本癌学会総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-16K10594
  • [Presentation] S100A4-MetAP2相互作用を阻害する合成ペプチドによる腫瘍血管新生と腫瘍増殖の抑制2016

    • Author(s)
      竹永啓三、落谷孝広、遠藤英也
    • Organizer
      第75回日本癌学会総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-16K10594
  • [Presentation] 可溶性ST2は炎症性のがん微小環境の修飾を介して大腸がんの増殖および転移を抑制する2016

    • Author(s)
      秋元美穂、丸山理留敬、竹永啓三
    • Organizer
      第14回がんとハイポキシア研究会
    • Place of Presentation
      岐阜グランドホテル(岐阜)
    • Year and Date
      2016-11-04
    • Data Source
      KAKENHI-PROJECT-16K10594
  • [Presentation] IL-33はprogrammed oncosis耐性高転移性肺癌細胞をがん微小環境下において選別する2016

    • Author(s)
      秋元美穂、竹永啓三
    • Organizer
      第25回日本がん転移学会
    • Place of Presentation
      米子コンベンションセンター(米子)
    • Year and Date
      2016-07-21
    • Data Source
      KAKENHI-PROJECT-16K10594
  • [Presentation] 膵がん細胞に対する生姜抽出物のautosis誘導を介した抗腫瘍効果2015

    • Author(s)
      竹永啓三、秋本美穂
    • Organizer
      第74回日本癌学会総会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] HIF-2αはヒト膵がん細胞のTRAIL細胞やT細胞による細胞傷害に対する感受性をsurvivinを介して制御する2015

    • Author(s)
      原嶋奈々江、秋本美穂、竹永啓三、原田守
    • Organizer
      第74回日本癌学会総会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2015-10-10
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] IL-33は腫瘍微小環境下においてprogrammed oncosis耐性高転移性肺癌細胞を選別する2015

    • Author(s)
      秋本美穂、竹永啓三
    • Organizer
      第13回がんとハイポキシア研究会
    • Place of Presentation
      三島(国立遺伝学研究所)
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] 膵がん細胞に対するアディポネクチン受容体アゴニストの抗腫瘍効果2015

    • Author(s)
      秋本美穂、竹永啓三
    • Organizer
      第74回日本癌学会総会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] 可溶性IL-33受容体sST2による炎症性 修飾を介した大腸がんの転移の抑制.2013

    • Author(s)
      秋元美穂、竹永啓三
    • Organizer
      第22回日本がん転移学会学術集会
    • Place of Presentation
      (松本)ブエナビスタ松本
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] 可容性IL-33受容体sST2による炎症性微小環境の修飾を介した大腸がんの転移の抑制2013

    • Author(s)
      秋元美穂、竹永啓三
    • Organizer
      第22回日本がん転移学会
    • Place of Presentation
      ホテルブエナビスタ松本(松本市)
    • Year and Date
      2013-07-11
    • Data Source
      KAKENHI-PUBLICLY-23112510
  • [Presentation] Soluble ST2 inhibits tumor growth and metastasis of colon carcinoma cells by modulating inflammatory microenvironment.2013

    • Author(s)
      Akimoto M, Honma Y, Takenaga K.
    • Organizer
      第72回日本癌学会総会
    • Place of Presentation
      (横浜)パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] Inhibition of tumor growth and metastasis of colon carcinoma cells by sST2.2012

    • Author(s)
      Akimoto M, Honma Y, Takenaga K.
    • Organizer
      The 71st Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      ホテルロイトン札幌(札幌市)
    • Year and Date
      2012-09-21
    • Data Source
      KAKENHI-PUBLICLY-23112510
  • [Presentation] IL-33はメタボリックストレス下でST2L陽性の肺がん細胞のネクローシスを促進する2011

    • Author(s)
      秋元美穂、本間良夫、竹永啓三
    • Organizer
      第9回がんとハイポキシア研究会
    • Place of Presentation
      学習院大学(東京)
    • Year and Date
      2011-11-26
    • Data Source
      KAKENHI-PUBLICLY-23112510
  • [Presentation] Effect of IL-33 on cell death of ST2L-positive and-negative lung carcinoma cells in hypoglycemic/hypoxic condition in vitro2011

    • Author(s)
      Keizo Takenaga, Miho Akimoto, Yoshio Honma
    • Organizer
      第70回日本癌会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PUBLICLY-23112510
  • [Presentation] The relationship between sST2 expression and tumor growth and metastasis in human colon carcinoma cells2011

    • Author(s)
      Miho Akimoto, Yoshio Honma, Keizo Takenaga
    • Organizer
      第70回日本癌会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PUBLICLY-23112510
  • [Presentation] Decrease in chemosensitivity to temozolomide in glioma cells co-cultured with astrocytes.2010

    • Author(s)
      Takenaga K, Akimoto M, Honma Y.
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-20591731
  • [Presentation] ヒト肺癌及び大腸癌の原発巣と転移巣におけるmtDNA変異頻度2010

    • Author(s)
      越川信子、木村秀樹、飯笹俊彦、井内俊彦、滝口伸浩、竹永啓三、中川原章
    • Organizer
      第19回日本癌病態治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-06-30
    • Data Source
      KAKENHI-PROJECT-21590349
  • [Presentation] Decreasein chemosensitivity to temozolomide in glioma cells co-cultured with astrocytes.2010

    • Author(s)
      Takenaga K, Akimoto M, Honma Y.
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-20591731
  • [Presentation] ヒト肺がんおよび大腸がんの原発巣と転移巣におけるmtDNA変異頻度の比較2009

    • Author(s)
      越川信子、木村秀樹、飯笹俊彦、井内俊彦、滝口伸浩、秋元美穂、本間良夫、竹永啓三
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21590349
  • [Presentation] 低酸素, ミトコンドリアとがんの転移2009

    • Author(s)
      竹永啓三(連携研究者)
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21590349
  • [Presentation] 低酸素、ミトコンドリアとがんの転移2009

    • Author(s)
      竹永啓三
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21590349
  • [Presentation] マウス由来細胞株および組織で発現する新規MCL-1バリアントの同定2008

    • Author(s)
      小嶋彰吾、百武明、越川信子、竹永啓三
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19591655
  • [Presentation] ROS産生を伴うミトコンドリアDNA突然変異によるヒトがん細胞の転移能の制御2008

    • Author(s)
      越川信子、石川香、今西秦赳、中田和人、林純一、竹永啓三
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19591655
  • [Presentation] HIF-2αによる幹細胞マーカーCD133遺伝子の発現制御2008

    • Author(s)
      望月重信、越川信子、原口清輝、中川原章、竹永啓三
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19591655
  • [Presentation] Modified expression of S100A4 protein in C6 glioma cells or surrounding astrocytes affects migration of the glioma cells2007

    • Author(s)
      Takenaga K, et. al.
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] Expression of cancer stem cell-related genes in hypoxia-resistant human lung adenocarcinoma A549 cells.2007

    • Author(s)
      Mochizuki S, Koshikawa N, Ohira M, Haraguchi S, Nakagawara A, Takenaga K.
    • Organizer
      The 66th Annual Meeting of The Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] Expression of cancer stem cell-related genes in hypoxia-resistant human lung adenocarcinoma A549 cells.2007

    • Author(s)
      S.Mochizuki, N.Koshikawa, M.Ohira, S.Haraguchi, A.Nakagawara, K.Takenaga.
    • Organizer
      第66回日本癌学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19591655
  • [Presentation] J-I. Enhancement of metastatic potential by a pathogenic missense mutation in mitochondrial ND6 gene.2007

    • Author(s)
      Takenaga K, Ishikawa K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Homa Y, Hayashi
    • Organizer
      The 16th Annual Meeting of The Japanese Association of Metastasis Research
    • Place of Presentation
      Toyama
    • Year and Date
      2007-07-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] ミトコンドリアND6遺伝子の病因性ミッセンス変異による転移能の亢進2007

    • Author(s)
      竹永啓三、石川 香、秋元美穂、越川信子、山口 綾、今西泰赳、中田和人、本間良夫、林 純一
    • Organizer
      第16回日本がん転移学会総会
    • Place of Presentation
      富山
    • Year and Date
      2007-07-09
    • Data Source
      KAKENHI-PROJECT-19591655
  • [Presentation] Reversible control of metastasis by a pathogenic mtDNA mutation in ND62007

    • Author(s)
      Koshikawa N, Ishikawa K, Akimoto M, Yamaguchi A, Imanishi H, Nakada K, Honma Y, Hayashi J-I, Takenaga K
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-19591655
  • [Presentation] Expression of cancer stem cell-related genes in hypoxia-resistant human lung adenocarcinoma A549 cells.2007

    • Author(s)
      S.Mochizuki, N.Koshikawa, M.Ohira, S.Haraguchi, A.Nakaga wara, K.Takenaga
    • Organizer
      第66回日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] ミトコンドリアND6遺伝子の病因性ミッセンス変異による転移能の亢進2007

    • Author(s)
      竹永啓三, 他
    • Organizer
      第16回日本がん転移学会総会
    • Place of Presentation
      富山
    • Year and Date
      2007-07-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] Expression of cancer stem cell-related genes in hypoxia-resistant human lung adenocarcinoma A549 cells2007

    • Author(s)
      Mochizuki S, Koshikawa N, Ohira M, Haraguchi S, Nakagawara A, Takenaga, K
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-19591655
  • [Presentation] Kozlova EN. Modified expression of S100A4 protein in C6 glioma cells or surrounding astrocytes affects migration of the glioma cells.2007

    • Author(s)
      Takenaga K, Nygren J, Zelenina M, Ohira M, Iuchi T, Lukanidine E, Sjouist M
    • Organizer
      The 66th Annual Meeting of The Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] Reversible control of metastasis by a pathogenic mtDNA mutation in ND6.2007

    • Author(s)
      Koshikawa N, Ishikawa K, Akimoto M, Yamaguchi A, Imanishi H, Nakada K, Honma Y, Hayashi J-I, Takenaga K.
    • Organizer
      The 66th Annual Meeting of The Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-10-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] Effects of hypoxia on the expressions of differentiation- and stem cell-related genes in human lung carcinoma A549 cells.2006

    • Author(s)
      Takenaga K, Koshikawa N, Mochizuki S, Takenobu H, Ohira M.
    • Organizer
      The 65th Annual Meeting of The Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2006-09-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] Cell-cidal effedct of the combination therapy of radio- and hypoxia-sensitized promoter-regulated p53 gene and heavy particle irradiation in glioma cells.2006

    • Author(s)
      Oga M, Koshikawa N, Nojima K, Takenaga K.
    • Organizer
      The 66th Annual Meeting of The Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2006-09-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] Induction of PDLIM2 gene expression by hypoxia and its role in cell motility and invasion of tumor cells.2006

    • Author(s)
      Ito S, Koshikawa N, Mochizuki S, Ohira M, Nakagawara A, Harigaya K, Takenaga K.
    • Organizer
      The 65th Annual Meeting of The Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2006-09-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] ヒト肺癌A549細胞株における分化及び幹細胞マーカー遺伝子発現に及ぼす低酸素の影響2006

    • Author(s)
      竹永啓三, 他
    • Organizer
      第65回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2006-09-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] Hypoxia stimulates dedifferentiation and metastatic potential of human lung carcinoma cells.2006

    • Author(s)
      Takenaga K, Koshikawa N, Mochizuki S, Takenobu H, Ohira M, Hori H, Nagasawa H, Uto Y.
    • Organizer
      The 4th Annual Meeting of The Japanese Association of Cancer and Hypoxia Research
    • Place of Presentation
      Kyoto
    • Year and Date
      2006-11-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] Hypoxia-response gene product NEDL1 degrades Dishevelled-1 and inhibits Dishevelled-l-stimulated differentiation of neuroblastoma cells.2006

    • Author(s)
      Mochizuki S, Koshikawa N, Ohira M, Nakagawara A, Takenaga K.
    • Organizer
      The 65th Annual Meeting of The Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2006-09-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] Hypoxia suppresses the expression of metastasis suppressor nm23-H1 gene in humanmammary. Carcinoma cells.2006

    • Author(s)
      Koshikawa N, Hori H, Nagasawa H, Uto Y, Takenaga K.
    • Organizer
      The 65th Annual Meeting of The Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2006-09-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] 低酸素はヒト肺がん細胞株の脱分化を促すとともに転移能を亢進する2006

    • Author(s)
      竹永啓三, 他
    • Organizer
      第4回がんとハイポキシア研究会
    • Place of Presentation
      京都
    • Year and Date
      2006-11-18
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590280
  • [Presentation] 間質細胞との共培養によるミトコンドリアDNA変異を有する肺がん細胞での解糖系と生存の促進

    • Author(s)
      竹永啓三、秋元美穂
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] 可溶性ST2は炎症性のがん微小環境を修飾し膵がんの増殖を抑制する

    • Author(s)
      秋元美穂、竹永啓三
    • Organizer
      第12回がんとハイポキシア研究会
    • Place of Presentation
      ホテルマリターレ創世佐賀(佐賀)
    • Year and Date
      2014-11-21 – 2014-11-22
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] HIF-2αの阻害はヒト膵がん細胞のTRAIL感受性を増強する

    • Author(s)
      原嶋奈々江、波里瑤子、門馬浩行、秋元美穂、竹永啓三、原田守
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-09-13 – 2014-09-14
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] 可溶性ST2は炎症性のがん微小環境を修飾し膵臓がんの腫瘍血管新生と増殖を抑制する

    • Author(s)
      秋元美穂、原田守,竹永啓三
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] HIF-2αの阻害はヒト膵がん細胞のTRAIL感受性を増強する

    • Author(s)
      原嶋奈々江、秋元美穂、竹永啓三、原田守
    • Organizer
      第12回がんとハイポキシア研究会
    • Place of Presentation
      ホテルマリターレ創世佐賀(佐賀)
    • Year and Date
      2014-11-21 – 2014-11-22
    • Data Source
      KAKENHI-PROJECT-25430110
  • [Presentation] 膵臓がん細胞に対する生姜抽出物の抗腫瘍効果

    • Author(s)
      兼松里衣、秋元美穂、竹永啓三
    • Organizer
      第61回日本生薬学会
    • Place of Presentation
      福岡大学(福岡)
    • Year and Date
      2014-09-13 – 2014-09-14
    • Data Source
      KAKENHI-PROJECT-25430110
  • 1.  KOSHIKAWA Nobuko (90260249)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 63 results
  • 2.  TAGAWA Masatoshi (20171572)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  OHIRA Miki (20311384)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  小林 進 (50234828)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  軍司 祥雄 (60241957)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  HAYASHI Jun-ichi (60142113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  OCHIAI Takenori (80114255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  OGA Masaru (10251159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  NOJIMA Kumie (90218272)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IWADATE Yasuo (70272309)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TAKENOBU Hisanori (60392247)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  HIROTA Kiichi (00283606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MATSUO Yoshiyuki (50447926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  磯野 可一 (70009489)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  永瀬 浩喜 (90322073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 17 results
  • 16.  渡部 隆義 (60526060)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 17.  秋元 美穂 (60437556)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 18.  丸 喜明 (30742754)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 19.  高取 敦志 (40455390)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  HATANO Kazuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  中田 和人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 22.  廣田 喜一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  市川 美紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 8 results
  • 24.  山本 清義
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 25.  LIN JASON
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 26.  筆宝 義隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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