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BUJO Hideaki  武城 英明

ORCIDConnect your ORCID iD *help
Researcher Number 80291300
Affiliation (based on the past Project Information) *help 2013 – 2023: 東邦大学, 医学部, 教授
2015: 東邦大学, 医療センター佐倉病院, 教授
2011 – 2012: 千葉大学, 医学(系)研究科(研究院), 教授
2007 – 2012: Chiba University, 大学院・医学研究院, 教授
2006: Graduate School of Medicine Chiba University, Department of Genome Research and Clinical Application(M6), Professor, 大学院医学研究院, 教授 … More
2004 – 2005: 千葉大学, 大学院・医学研究院, 教授
2001: Chiba University, Graduate School of medicine, Professor, 大学院・医学研究院, 教授
2000: Chiba University, School of medicine, Associate Professor, 医学部, 講師
1999: Chiba University,University Hospital,Assistant, 医学部・付属病院, 助手
1997 – 1999: 千葉大学, 医学部・附属病院, 助手
1997 – 1998: 千葉大学, 医学部, 助手
1997: 千葉大学, 医学部・付属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Metabolomics / Laboratory medicine / Medium-sized Section 52:General internal medicine and related fields / 内分泌・代謝学
Except Principal Investigator
Metabolomics / 内分泌・代謝学 / Hematology / Metabolomics / 老化(加齢) / Plastic surgery
Keywords
Principal Investigator
LR11 / 動脈硬化 / 分化 / アルツハイマー病 / 可溶性 / 糖尿病 / 平滑筋細胞 / 可溶性LR11 / 熱産生 / 基礎代謝 … More / 褐色脂肪 / 血管 / 神経細胞 / モデル動物 / 脂肪細胞 / 細胞骨格 / バイオマーカー / 遊走 / 可溶型LR11 / アルツハイマー / 免疫染色 / アミロイド前駆体タンパク / 脳組織 / プロテアーゼ / プロセシング異常 / 免疫学的解析 / アポEレセプター / インスリン抵抗性 / 検査学 / ブラウニング / 黄斑前膜 / 肺高血圧 / 肺高血圧症 / リンパ腫 / 検査マーカー / 病的細胞 / LR11 / Differentiation / Migration / Blood vessel / Smooth muscle cell / Arteriosclerosis / Smooth muscle cells / Atherosclerosis / LDLR / LDL受容体 / LR32 / リボ蛋白 / animal model / gene family / atherosclerosis / ジーンターゲッチング / クローニング / 遺伝子ファミリー / 肥満 / 褐色細胞 / 白血病 / トランスディファレンシエーション / エネルギー産生 / 褐色 / 血管傷害 / 運動能 / 細胞遊走 / 単球 / 脂質代謝異常 / リコンビナント / アンギオテンシンII / 内膜中膜肥厚 … More
Except Principal Investigator
LR11 / 脂肪細胞 / LDL / 受容体 / 糖尿病 / 肥満 / 動脈硬化 / ファミリー / 遺伝子 / 血管新生 / 脂肪組織 / 皮下脂肪 / モデル動物 / 可溶性LR11 / 褐色脂肪 / ノックアウトマウス / インスリン抵抗性 / 褐色分化 / 熱代謝 / 機能獲得 / 褐色細胞 / エネルギー消費 / 急性骨髄性白血病 / バイオマーカー / 血清マーカー / 血管内大細胞性B細胞型リンパ腫 / びまん性大細胞性B細胞型リンパ腫 / 急性白血病 / 悪性リンパ腫 / 予後予測システム / 新規バイオマーカー / BDNF / アルツハイマー病 / アミロイドβ / アルツハイマー / ネプリライシン / アルツハイマー認知症 / 脂肪幹細胞 / Cross-talk / Diabetes / Obesity / Vascular cells / Adipocyte / 脂肪蓄積 / 血管内皮増殖因子 / 血管内皮細胞 / クロストーク / 血管壁細胞 / Smooth muscle cells / Atherosclerosis / LDLR / LR32 / リポ蛋白受容体 / oxygen damage / mitochondria / cultured skin fibroblasts / Werner syndrome / cellular senescence / TIG103細胞 / 中膜平滑筋細胞 / 抗酸化剤 / 酸化傷害 / ミトコンドリア / 培養皮膚線維芽細胞 / Werner症候群 / 細胞老化 / ECM / re-stenosis / cytokine / athevosclevosis / intima / 遺伝子発現 / 平滑筋細胞 / 遺伝子導入 / サイトカイン / 血管平滑筋細胞 / atheroscleosis / brain / receptor / gene family / 細胞接着 / 低酸素 / ニッチ / 白血病 / 血液腫瘍学 / 生着 / マトリックス / bFGF / 生存 / 細胞外マトリクス / 移植 / 内臓脂肪 / 腸間膜因子 / 培養 / 神経細胞 / クローニング Less
  • Research Projects

    (21 results)
  • Research Products

    (100 results)
  • Co-Researchers

    (32 People)
  •  Exploration of the pathological relationship between diabetes and Alzheimer's disease through disruption of soluble apoE receptor shearing and releasePrincipal Investigator

    • Principal Investigator
      Bujo Hideaki
    • Project Period (FY)
      2018 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Toho University
  •  Examinational significance and production mechanism of a circulating soluble receptor for the diagnosis of activated adipocytes to prevent diabetesPrincipal Investigator

    • Principal Investigator
      BUJO Hideaki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Toho University
  •  Identification of the pathologically-transited immature cells diagnosed by soluble LR11Principal Investigator

    • Principal Investigator
      BUJO Hideaki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Toho University
  •  Molecular basis of the severe ectopic browning transition of adipocytes in novel mice with resistance against obesity and diabetes

    • Principal Investigator
      JIANG Meizi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Toho University
  •  Elucidation of restoration mechanisms in Alzheimer diseases by mobilized stem cells through activation of adipose tissue

    • Principal Investigator
      KURODA Masayuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Chiba University
  •  An establishment of serum soluble LR11, as a novel biomarker in patients with acute leukemia and malignant lymphoma

    • Principal Investigator
      OHWADA Chikako
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Chiba University
  •  Molecular clarification of trans-differentiation to brown adipocytes through the action of soluble receptor LR11Principal Investigator

    • Principal Investigator
      BUJO Hideaki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Toho University
      Chiba University
  •  Analysis of the function of LR11 on normal leukocytes and leukemia cells

    • Principal Investigator
      TAKEUCHI Masahiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Chiba University
  •  Regulation of cellular cytoskeleton by the soluble LDL receptor family with the application for novel anti-atherosclerosis therapyPrincipal Investigator

    • Principal Investigator
      BUJO Hideaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Chiba University
  •  Amelioration of pathological phenotypes of vascular smooth muscle cells by the sLR11 regulationPrincipal Investigator

    • Principal Investigator
      BUJO Hideaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Chiba University
  •  Mechanism of angiogenesis for adipocytes for the application to the stable transplantation technique

    • Principal Investigator
      RIKIHISA Naoaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Chiba University
  •  Molecular analysis and clinical application of LR11 in SMCs.Principal Investigator

    • Principal Investigator
      BUJO Hideaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Chiba University
  •  Molecular mechanism of cross-talk between adipocytes and vascular cells.

    • Principal Investigator
      SAITO Yasushi, 高橋 和男
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Chiba University
  •  培養脂肪細胞に分化を促進する脂肪組織側因子の解明

    • Principal Investigator
      齋藤 康 (斎藤 康)
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      Chiba University
  •  Functional analysis of LR11 in vascular smooth muscle cellsPrincipal Investigator

    • Principal Investigator
      BUJO Hideaki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Institution
      CHIBA UNIVERSITY
  •  Analysis of new lipoprotein receptors using animal models

    • Principal Investigator
      SAITO Yasushi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Metabolomics
    • Research Institution
      Chiba University
  •  新たな脳特異的LDL受容体類似蛋白の神経発達および病態生理における機能解明

    • Principal Investigator
      SAITO Yasushi
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内分泌・代謝学
    • Research Institution
      Chiba University
  •  Molecular analysis of the LDL receptor gene family members

    • Principal Investigator
      SAITO Yasushi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      内分泌・代謝学
    • Research Institution
      CHIBA UNIVERSITY
  •  Modification of Athferoma by cytokin gene transfer

    • Principal Investigator
      SAITO Yasushi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Chiba University
  •  Functional analysis of the brain-specific LDL receptor family memnersPrincipal Investigator

    • Principal Investigator
      BUJO Hideaki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      CHIBA UNIVERSITY
  •  Research on abnormal mitochondria and its change in gene expression in cellular senescence.

    • Principal Investigator
      MURANO Shunichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      老化(加齢)
    • Research Institution
      Akita University
      Chiba University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

  • [Journal Article] Soluble LR11 as a Novel Biomarker in Acute Kawasaki Disease2022

    • Author(s)
      Watanabe Kenichi、Suzuki Hiroshi、Jiang Meizi、Tsukano Shinya、Kataoka Satoshi、Ito Sueshi、Sakai Takatsugu、Hirokawa Toru、Saitoh Akihiko、Bujo Hideaki
    • Journal Title

      Circ J

      Volume: 86 Issue: 6 Pages: 977-983

    • DOI

      10.1253/circj.CJ-20-1271

    • NAID

      130008088823

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2022-05-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07840, KAKENHI-PROJECT-18K19526, KAKENHI-PROJECT-18K07428
  • [Journal Article] LR11, an LDL Receptor Gene Superfamily Member, Represses the Norepinephrine-Induced Expression of Uncoupling Protein 1 in Primary Cultured Beige Adipocytes2021

    • Author(s)
      Shoko Nakamura, Meizi Jiang, Rena Oka, Takashi Yamaguchi, Nobuyuki Hiruta, Hiroyuki Ebinuma, Wolfgang J Schneider, Ichiro Tatsuno and Hideaki Bujo
    • Journal Title

      Toho Journal of Medicine

      Volume: 7 Issue: 1 Pages: 48-56

    • DOI

      10.14994/tohojmed.2020-019

    • NAID

      120006976149

    • ISSN
      21891990
    • URL

      https://toho.repo.nii.ac.jp/records/2002962

    • Year and Date
      2021-03-01
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07428, KAKENHI-PROJECT-18K19526
  • [Journal Article] Impact of LR11 as Residual Risk on Long-Term Clinical Outcomes in Patients with Coronary Artery Disease Treated with Statins after First Percutaneous Coronary Intervention2020

    • Author(s)
      Suwa Satoru、Ogita Manabu、Takahashi Norihito、Wada Hideki、Dohi Tomotaka、Kasai Takatoshi、Okazaki Shinya、Shimada Kazunori、Miyauchi Katsumi、Bujo Hideaki、Daida Hiroyuki
    • Journal Title

      Int. Heart J.

      Volume: 61 Issue: 3 Pages: 470-475

    • DOI

      10.1536/ihj.19-686

    • NAID

      130007849620

    • ISSN
      1349-2365, 1349-3299
    • Year and Date
      2020-05-30
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19526
  • [Journal Article] Levels of circulating soluble LR11, a regulator of smooth muscle cell migration, are highly associated with atherosclerotic plaques in patients with carotid artery stenosis2019

    • Author(s)
      Harada M, Jiang M, Terai K, Ebinuma H, Hiruta N, Schneider WJ, Sugo N, Nagao T, Bujo H
    • Journal Title

      Clin Chim Acta

      Volume: 490 Pages: 69-76

    • DOI

      10.1016/j.cca.2018.12.005

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07428, KAKENHI-PROJECT-16H05231
  • [Journal Article] Soluble LR11 competes with amyloid β in binding to cerebrospinal fluid?high-density lipoprotein2019

    • Author(s)
      Yano Kouji、Hirayama Satoshi、Misawa Naomi、Furuta Ayaka、Ueno Tsuyoshi、Motoi Yumiko、Seino Utako、Ebinuma Hiroyuki、Ikeuchi Takeshi、Schneider Wolfgang J.、Bujo Hideaki、Miida Takashi
    • Journal Title

      Clinica Chimica Acta

      Volume: 489 Pages: 29-34

    • DOI

      10.1016/j.cca.2018.11.024

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H07095, KAKENHI-PROJECT-18K07477, KAKENHI-PROJECT-19K07874, KAKENHI-PROJECT-18K19526
  • [Journal Article] Susceptibilities of epicardial and subcutaneous fat tissue for browning-gene expression and diet-induced volume reduction are different2018

    • Author(s)
      Mikamo H, Jiang M, Noro M, Suzuki Y, Hiruta N, Unoki-Kubota H, Schneider WJ, Bujo H.
    • Journal Title

      Mol Med Rep

      Volume: 17 Pages: 6542-6550

    • DOI

      10.3892/mmr.2018.8690

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05231, KAKENHI-PROJECT-18K07428
  • [Journal Article] Soluble form of LR11 is highly increased in the vitreous fluids of patients with idiopathic epiretinal membrane.2017

    • Author(s)
      Hashimoto R, Jiang M, Shiba T, Hiruta N, Takahashi M, Higashi M, Hori Y, Bujo H, Maeno T.
    • Journal Title

      Graefes Arch Clin Exp Ophthalmol.

      Volume: 255 Issue: 5 Pages: 885-891

    • DOI

      10.1007/s00417-017-3585-1

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15198, KAKENHI-PROJECT-15K10882
  • [Journal Article] Prognostic impact of serum soluble LR11 in newly diagnosed diffuse large B-cell lymphoma: A multicenter prospective analysis.2016

    • Author(s)
      Sugita Y, Ohwada C, Kawaguchi T, Muto T, Tsukamoto S, Takeda Y1, Mimura N, Takeuchi M , Sakaida E, Shimizu N, Tanaka H, Abe D, Fukazawa M, Sugawara T, Aotsuka N, Nishiwaki K, Shono K, Ebinuma H, Fujimura K, Bujo H, Yokote K, Nakaseko C.
    • Journal Title

      Clin Chim Acta.

      Volume: 463 Pages: 47-52

    • DOI

      10.1016/j.cca.2016.10.008

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15198
  • [Journal Article] Circulating soluble form of LR11, a regulator of smooth muscle cell migration, is a novel marker for intima-media thickness of carotid arteries in type 2 diabetes.2016

    • Author(s)
      Jin W, Jiang M, Han X, Han X, Murano T, Hiruta N, Ebinuma H, Piao L, Schneider WJ, Bujo H.
    • Journal Title

      Clin Chim Acta.

      Volume: 457 Pages: 137-141

    • DOI

      10.1016/j.cca.2016.04.016

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05231
  • [Journal Article] Deletion of LR11 attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation with medial thickening in mice.2016

    • Author(s)
      Jiang L, Konishi H, Nurwidya F, Satoh K, Takahashi F, Ebinuma H, Fujimura K, Takasu K, Jiang M, Shimokawa H, Bujo H, Daida H.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 36 Issue: 9 Pages: 1972-1979

    • DOI

      10.1161/atvbaha.116.307900

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-15K15198, KAKENHI-PROJECT-15K09127
  • [Journal Article] Prognostic impact of circulating soluble LR11 on long-term clinical outcomes in patients with coronary artery disease2016

    • Author(s)
      Ogita M, Miyauchi K, Kasai T, Tsuboi S, Wada H, Naito R, Konishi H, Dohi T, Tamura H, Okazaki S, Yanagisawa N, Shimada K, Suwa S, Jiang M, Bujo H, Daida H
    • Journal Title

      Atherosclerosis

      Volume: 244 Pages: 216-221

    • DOI

      10.1016/j.atherosclerosis.2015.11.004

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15198, KAKENHI-PROJECT-16K19431
  • [Journal Article] Levels of the soluble LDL receptor-relative LR11 decrease in overweight individuals with type 2 diabetes upon diet-induced weight loss.2016

    • Author(s)
      Berk KA, Vongpromek R, Jiang M, Schneider WJ, Timman R, Verhoeven AJ, Bujo H, Sijbrands EJ, Mulder MT.
    • Journal Title

      Atherosclerosis.

      Volume: 254 Pages: 67-72

    • DOI

      10.1016/j.atherosclerosis.2016.09.066

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05231
  • [Journal Article] Serum soluble LR11, a novel tumor derived biomarker associated with the outcome of patients with diffuse large B-cell lymphoma.2015

    • Author(s)
      Ohwada C, Yamazaki A, Kawaguchi T, Sugita Y, Takeuchi M, Shimizu N, Sakaida E, Takeda Y, Tsukamoto S, Muto T, Jiang M, Higashi M, Yokote K, Tamaru JI, Bujo H, Nakaseko C.
    • Journal Title

      Leuk Lymphoma.

      Volume: 印刷中 Issue: 10 Pages: 1-4

    • DOI

      10.3109/10428194.2015.1016930

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-25461409, KAKENHI-PROJECT-15K15198, KAKENHI-PROJECT-15K08366, KAKENHI-PROJECT-26670362, KAKENHI-PROJECT-26293165
  • [Journal Article] Soluble LR11 is a novel biomarker for vascular lesions late after Kawasaki disease.2015

    • Author(s)
      Watanabe K, Suzuki H, Jiang M, Haniu H, Numano F, Hoshina S, Saitoh A, Uchiyama M, Bujo H.
    • Journal Title

      Atherosclerosis

      Volume: 246 Pages: 94-97

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461369
  • [Journal Article] Prognostic impact of circulating soluble LR11 on long-term clinical outcomes in patients with coronary artery disease.2015

    • Author(s)
      Ogita M, Miyauchi K, Kasai T, Tsuboi S, Wada H, Naito R, Konishi H2, Dohi T2, Tamura H2, Okazaki S2, Yanagisawa N, Shimada K, Suwa S, Jiang M, Bujo H, Daida H
    • Journal Title

      Atherosclerosis

      Volume: 244 Pages: 216-221

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461369
  • [Journal Article] Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans.2015

    • Author(s)
      Whittle AJ, Jiang M, Peirce V, Relat J, Virtue S, Ebinuma H, Fukamachi I, Yamaguchi T, Takahashi M, Murano T, Tatsuno I, Takeuchi M, Nakaseko C, Jin W, Jin Z, Campbell M, Schneider WJ, Vidal-Puig A, Bujo H.
    • Journal Title

      Nat Commun

      Volume: 6 Issue: 1 Pages: 8951-8951

    • DOI

      10.1038/ncomms9951

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461369
  • [Journal Article] Tetraspanin CD9 modulates ADAM17-mediated shedding of LR11 in leukocytes.2014

    • Author(s)
      Tsukamoto S, Takeuchi M, Kawaguchi T, Togasaki E, Yamazaki A, Sugita Y, Muto T, Sakai S, Takeda Y, Ohwada C, Sakaida E, Shimizu N, Nishii K, Jiang M, Yokote K, Bujo H, Nakaseko C.
    • Journal Title

      Exp Mol Med.

      Volume: - Issue: 4 Pages: 46-89

    • DOI

      10.1038/emm.2013.161

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-26461369
  • [Journal Article] G-CSF induces the release of the soluble form of LR11, a regulator of myeloid cell mobilization in bone marrow2014

    • Author(s)
      Shimizu N, Nakaseko C, Jiang M, Nishii K, Yokote K, Iseki T, Higashi M, Tamaru J, Schneider WJ, Bujo H
    • Journal Title

      Ann Hematol

      Volume: (印刷中) Issue: 7 Pages: 1111-1122

    • DOI

      10.1007/s00277-014-2033-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590413, KAKENHI-PROJECT-24390231, KAKENHI-PROJECT-24591380
  • [Journal Article] Potential utility of serum soluble LR11 as a diagnostic biomarker for intravascular large B-cell lymphoma2014

    • Author(s)
      Kawaguchi T, Ohwada C, Takeuchi M, Shimizu N, Sakaida E, Takeda Y, Sakai S, Tsukamoto S, Yamazaki A, Sugita Y, Higashi M, Fujikawa K, Matsue K, Yokote K, Tamaru JI, Bujo H, Nakaseko C
    • Journal Title

      Leuk Lymphoma

      Volume: (印刷中) Issue: 10 Pages: 2391-2394

    • DOI

      10.3109/10428194.2014.880430

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590413, KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-25461409
  • [Journal Article] Circulating soluble LR11, a novel marker of smooth muscle cell proliferation, is enhanced after coronary stenting in response to vascular injury.2014

    • Author(s)
      Ogita M, Miyauchi K, Jiang M, Kasai T, Tsuboi S, Naito R, Konishi H1, Dohi T1, Yokoyama T, Okazaki S, Shimada K, Bujo H, Daida H
    • Journal Title

      Atherosclerosis.

      Volume: 237 Pages: 374-378

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461369
  • [Journal Article] Circulating soluble LR11, a novel marker of smooth muscle cell proliferation, is enhanced after coronary stenting in response to vascular injury.2014

    • Author(s)
      Ogita M, Miyauchi K, Jiang M, Kasai T, Tsuboi S, Naito R, Konishi H, Dohi T, Yokoyama T, Okazaki S, Shimada K, Bujo H, Daida H.
    • Journal Title

      Atherosclerosis

      Volume: 237 Pages: 374-378

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390231
  • [Journal Article] The soluble form of LR11 is a regulator of hypoxia-induced, uPAR-mediated adhesion of immature hematological cells2013

    • Author(s)
      Keigo Nishii, Chiaki Nakaseko, Meizi Jiang, Naomi Shimizu, Masahiro Takeuchi, Wolfgang Johann Schneider, and Hideaki Bujo
    • Journal Title

      J Biol Chem

      Volume: 288(17) Pages: 11877-86

    • Data Source
      KAKENHI-PROJECT-23591368
  • [Journal Article] The soluble form of LR11 is a regulator of hypoxia-induced, uPAR-mediated adhesion of immature hematological cells2013

    • Author(s)
      Keigo Nishii, Chiaki Nakaseko, Meizi Jiang, Naomi Shimizu, Masahiro Takeuchi, Wolfgang Johann Schneider, and Hideaki Bujo
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 288(17) Issue: 17 Pages: 11877-11886

    • DOI

      10.1074/jbc.m112.442491

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591368, KAKENHI-PROJECT-24390231, KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-24790907
  • [Journal Article] LR11 : a novel biomarker identified in follicular lymphoma2013

    • Author(s)
      Kawaguchi T, Ohwada C, Takeuchi M, Shimizu N, Sakaida E, Takeda Y, Sakai S, Tsukamoto S, Yamazaki A, Sugita Y, Jiang M, Higashi M, Yokote K, Tamura J, Bujo H, Nakaseko C
    • Journal Title

      Br J Haematol

      Volume: 163(2) Issue: 2 Pages: 277-280

    • DOI

      10.1111/bjh.12467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390185, KAKENHI-PROJECT-23590413, KAKENHI-PROJECT-24390231, KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-24659346, KAKENHI-PROJECT-24790907, KAKENHI-PROJECT-25461409
  • [Journal Article] SORL1 genetic variants and cerebrospinal fluid biomarkers of Alzheimer's disease2012

    • Author(s)
      Guo L-H, Guo, Westerteicher C, Wang X-H, Kratzer M, Tsolakidou A, Jiang M, Grimmer T, Laws SM, Alexopoulos P, Bujo H, Kurz A, Perneczky R
    • Journal Title

      Eur Arch Psychiatry Clin Neurosci

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Platelet-rich plasma inhibits the apoptosis of highly adipogenic homogeneous preadipocytes in an in vitro culture system.2012

    • Author(s)
      Fukaya Y, Kuroda M, Aoyagi Y, Asada S, Kubota Y, Okamoto Y, Nakayama T, Sai to Y, Satoh Y, Bujo H
    • Journal Title

      Exp Mol Med

      Volume: 44 Issue: 5 Pages: 330-339

    • DOI

      10.3858/emm.2012.44.5.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390231
  • [Journal Article] Platelet-rich plasma inhibits the apoptosis of highly adipogenic homogeneous preadipocytes in an in vitro culture system2012

    • Author(s)
      Fukaya Y, Kuroda M, Aoyagi Y, Asada S, Kubota Y, Okamoto Y, Nakayama T, Saito Y, Satoh Y, Bujo H
    • Journal Title

      Exp Mol Med

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Fibrin glue is a candidate scaffold for long-term therapeutic protein expression in spontaneously differentiated adipocytes in vitro2012

    • Author(s)
      Aoyagi Y, Kuroda M, Asada S, Tanaka S, Konno S, Tanio T, Aso M, Okamoto Y, Nakayama T, Saito Y, Bujo H
    • Journal Title

      Exp Cell Res

      Volume: 318 Issue: 1 Pages: 8-15

    • DOI

      10.1016/j.yexcr.2011.10.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Enhancved cir-culating soluble LR11 in patients with diabetic retinopathy2012

    • Author(s)
      Takahashi M, Bujo H, Shiba T, Jiang M, Maeno T, Shirai K
    • Journal Title

      Am J Ophthalmol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Enhanced circulating soluble LR11 in patients with diabetic retinopathy2012

    • Author(s)
      Takahashi M, Bujo H, Shiba T, Jiang M, Maeno T, Shirai K
    • Journal Title

      Am J Ophthalmol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Circulating Soluble LRU in Patients with Diabetic Retinopathy.2012

    • Author(s)
      Takahashi M, Bujo H, Shiba T, Jiang M, Maeno T, Shirai K
    • Journal Title

      Am J Ophthalmol

      Volume: 154 Issue: 1 Pages: 187-192

    • DOI

      10.1016/j.ajo.2012.01.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390231, KAKENHI-PROJECT-24790907
  • [Journal Article] BACE1 activity is re-lated to CSF concentrations of SORL1, soluble amyloid precursor protein and tau2012

    • Author(s)
      Tsolakidou A, Alexopoulos P, Guo L-H, Guo, Grimmer T, Westerteicher C, Kratzer M, Jiang M, Bujo H, Rosselli F, Leante MR, Livrea P, Kurz A, Perneczky R
    • Journal Title

      Alzheimers Dement

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Adipocytes as a vehicle for ex vivo gene therapy Novel replacement the rapy for diabetes and other metabol ic diseases2011

    • Author(s)
      Kuroda M, Bujo H, Aso M, Saito Y
    • Journal Title

      J Diabet Invest

      Volume: 2 Issue: 5 Pages: 333-340

    • DOI

      10.1111/j.2040-1124.2011.00133.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Ceiling culture-derived proliferative adipocytes retain high adipogenic potential suitable for use as a vehicle for gene transduction therapy2011

    • Author(s)
      Asada S, Kuroda M, Aoyagi Y, Fukaya Y, Tanaka S, Konno S, Tanio M, Aso M, Okamoto Y, Nakayama T, Saito Y, Bujo H
    • Journal Title

      Am J Physiol Cell Physiol

      Volume: 301 Issue: 1 Pages: C181-C185

    • DOI

      10.1152/ajpcell.00080.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Disturbed apolipoprotein A-I-containing lipoproteins in fish-eye disease are improved by the lecithin : cholesterol acyltransferase produced by gene-transduced adipocytes in vitro2011

    • Author(s)
      Asada, S., Kuroda, M., Aoyagi, Y., Bujo, H., Tanaka, S., Konno, S., Tanio, M., Ishii, I., Aso, M., Saito, Y.
    • Journal Title

      Mol Genet Metab.

      Volume: 102 Pages: 229-231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Interrelations between CSF soluble APP, amyloid-b 1-42, SORL1, and tau levels in Alzheimer's disease2011

    • Author(s)
      Alexopoulos P, Luo L-H, Tsolakidou A, Kratzer M, Grimmer T, Westerteicher C, Jiang M, Bujo H, Diehl-Schmid J, Kurz A, Perneczky R
    • Journal Title

      J Alzheimers Dis

      Volume: 28(3) (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Crystallization and preliminary crystallographic anal-ysis of human LR11 Vps10p domain2011

    • Author(s)
      Nakata Z, Nagae M, Yasui N, Bujo H, Nogi T, Takagi J
    • Journal Title

      Acta Crystallogr Sect F Struct Biol Cryst Commun

      Volume: 67 Issue: 1 Pages: 129-132

    • DOI

      10.1107/s1744309110048153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277, KAKENHI-PUBLICLY-22121513, KAKENHI-PROJECT-22247010, KAKENHI-PROJECT-22370039
  • [Journal Article] Ceiling culture-derived proliferative adipocytes retain high a dipogenic potential suitable for use as a vehicle for gene transduction therapy2011

    • Author(s)
      Asada S, Kuroda M, Aoyagi Y, Fukaya Y, Tanaka S, Konno S, Tanio M, Aso M, Okamoto Y, Nakayama T, Saito Y, Bujo H
    • Journal Title

      Am J Physiol Cell Physiol

      Volume: 301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Fibrin glue increases the cell survival and the transduced gene product secretion of the ceiling culture-derived adipocytes trans-planted in mice2011

    • Author(s)
      Aoyagi Y, Kuroda M, Asada S, Bujo H, Tanaka S, Konno S, Tanio M, Ishii I, Aso M, Saito Y
    • Journal Title

      Exp Mol Med

      Volume: 243 Issue: 3 Pages: 161-167

    • DOI

      10.3858/emm.2011.43.3.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Enhanced circulating solubule LR11 in patients with coronary organic stenosis.2010

    • Author(s)
      Takahashi M, Bujo H, Jiang M, Noike H, Saito Y, Shirai K.
    • Journal Title

      Atherosclerosis

      Volume: 210(2) Pages: 581-584

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Enhanced circu-lating soluble LR11 in patients with coronary organic stenosis2010

    • Author(s)
      Takahashi M, Bujo H, Jiang M, Noike H, Saito Y, Shirai K
    • Journal Title

      Athero-sclerosis

      Volume: 210 Pages: 581-584

    • URL

      http://dx.doi.org/10.1016/j.atherosclerosis.2009.12.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Enhanced circulating soluble LR11 in patients with coronary organic stenosis.2010

    • Author(s)
      Takahashi M, Bujo H, Jiang M, Noike H, Saito Y, Shirai K.
    • Journal Title

      Atherosclerosis

      Volume: 210(2) Pages: 581-584

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Increased Levels of Soluble LR11 in Cerebrospinal Fluid of Patientswith Alzheimer Disease.2010

    • Author(s)
      Ikeuchi, T., Hirayama, S., Miida, T., Fukamachi, I., Tokutake, T., Ebinuma, H., Takubo, K., Kaneko, H., Kasuga, K., Kakita, A Takahashi, H., Bujo, H., Saito, Y., Nishizawa, M.
    • Journal Title

      Dement Geriatr Cogn Disord.

      Volume: 30 Pages: 28-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Increased Levels of Soluble LR11 in Cerebrospinal Fluid of Patients with Alzheimer Disease2010

    • Author(s)
      Ikeuchi T, Hirayama S, Miida T, Fukamachi I, Tokutake T, Ebinuma H, Takubo K, Kaneko H, Kasuga K, Kakita A, Takahashi H, Bujo H, Saito Y, Nishizawa M
    • Journal Title

      Dement Geriatr Cogn Disord

      Volume: 30 Issue: 1 Pages: 28-32

    • DOI

      10.1159/000315539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277, KAKENHI-PROJECT-22590535
  • [Journal Article] Development of an immunoassay for the quantification of solbule LR11, A circulating marker of atherosclerosis.2009

    • Author(s)
      Matsuo M, Ebinuma H, Fukamachi I, Jiang M, Bujo H, Saito Y.
    • Journal Title

      Cline Chem

      Volume: 55(10) Pages: 1801-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Plasma pre beta1-HDL level is elevated in unstable angina pectoris.2009

    • Author(s)
      Tashiro J, Miyazaki O, Nakamura Y, Miyazaki A, Fukamachi I, Bujo H, Saito Y.
    • Journal Title

      Atherosclerosis

      Volume: 204(2) Pages: 595-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] Development of an immunoassay for the quantification of soluble LR11, a circu-lating marker of atherosclerosis2009

    • Author(s)
      Matsuo M, Ebinuma H, Fukamachi I, Jiang M, Bujo H, Saito Y
    • Journal Title

      Clin Chem

      Volume: 55 Issue: 10 Pages: 1801-1808

    • DOI

      10.1373/clinchem.2009.127027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390277
  • [Journal Article] The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease2009

    • Author(s)
      Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, Zou F, Katayama T, Baldwin CT, Cheng R, Hasegawa H, Chen F, Sjobata N, Lunetta KL, Pardossi-Piquard R, Bohm C, Wakutani Y, Cupples LA, Cuenco KT, Green RC, Pinessi L, Rainero I, Sorbi S, Bruni A, Duara R, Friedland RP, Inzelberg R, Hampe W, Bujo H, Song YQ, Andersen OM, Willnow TE, Graff-Radford N, Prtersen RC, Dickson D, Der SD, Fraser PE, Schmitt-Ulms G, Younkin S, Mayeux R, Farrer LA, St. George-Hyslop P.
    • Journal Title

      Nat. Genet 39

      Pages: 168-177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591036
  • [Journal Article] Matrix metalloproteinase-3 enhances the free fatty acids-induced VEGF expression in adipocytes through toll-like receptor 22008

    • Author(s)
      Kawamura T, Murakami K, Bujo H, Unoki H, Jiang M, Nakayama T, Saito Y.
    • Journal Title

      Exp.Biol. Med. (Maywood) 233

      Pages: 1213-1221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592069
  • [Journal Article] Macrophages regulate tumor necrosis factor-alpha expression in adipocytes through the secretion of matrix metalloproteinase-32008

    • Author(s)
      Unoki H, Bujo H, Jiang M, Kawamura T, Murakami K, Saito Y.
    • Journal Title

      Int. J. Obes 32

      Pages: 902-911

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592069
  • [Journal Article] Low-dose GH supplementation reduces the TLR2 and TNF-alpha expressions in visceral fat2008

    • Author(s)
      Kubota Y, Unoki H, Bujo H, Rikihisa N, Udagawa A, Yoshimoto S, Ichinose M, Saito Y
    • Journal Title

      Biochem Biophys Res Commun 368

      Pages: 81-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592069
  • [Journal Article] Matrix metalloproteinase-3 enhances the free fatty acids-induced VEGF expression in adipocytes through toll-like receptor 2.2008

    • Author(s)
      Kawamura T, Murakami K, Bujo H, Unoki H, Jiang M, Nakayama T, Saito Y.
    • Journal Title

      Exp. Biol. Med.(Maywood) 233

      Pages: 1213-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592069
  • [Journal Article] Low-dose GH supplementation reduces the TLR2 and TNF-alpha expressions in visceral fat2008

    • Author(s)
      Kubota Y, Unoki H, Bujo H, Rikihisa N, Udagawa A, Yoshimoto S, Ichinose M, Saito Y.
    • Journal Title

      Biochem. Biophys. Res. Commun. 368

      Pages: 81-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592069
  • [Journal Article] AngII-stimulated migration of vascular SMC is dependent on LR11.2008

    • Author(s)
      Jiang M, Bujo H, Ohwaki K, Unoki H, Yamazaki H, Kanaki T, Shibasaki M, Azuma K, Harigaya K, Schneider WJ, Saito Y
    • Journal Title

      J. Clin. Invest. 118

      Pages: 2733-2746

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591036
  • [Journal Article] Low-dose GH supplementation reduces the TLR2 and TNF-alpha expressions in visceral fat.2008

    • Author(s)
      Kubota Y, Unoki H, Bujo H, Rikihisa N, Udagawa A, Yoshimoto S, Ichinose M, Saito Y.
    • Journal Title

      Biochem. Biophys. Res. Commun. 368

      Pages: 81-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592069
  • [Journal Article] AngII-stimulated migration of vascular SMC is dependent on LR112008

    • Author(s)
      Jiang M, Bujo H, Ohwaki K, Unoki H, Yamazaki H, Kanaki T, Shibasaki M, Azuma K, Harigaya K, Schneider WJ, Saito Y.
    • Journal Title

      J. Clin. Invest 118

      Pages: 2733-2746

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591036
  • [Journal Article] Basic fibroblast growth factor ameliorates the survival of transplanted adipocytes thlough matrix metalloproteinase 2 in mice.2008

    • Author(s)
      Kuramochi D, Unoki H, Bujo H, Kubota Y, Jiang M, Rikihisa N, Udagawa A, Yoshimoto S, Ichinose M, Saito Y.
    • Journal Title

      Eur.J.Clin.Invest. 38

      Pages: 752-59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592069
  • [Journal Article] Matrix metalloproteinase 2 improves the transplanted adipocyte survival in mice2008

    • Author(s)
      Kuramochi D, Unoki H, Bujo H, Kubota Y, Jiang M, Rikihisa N, Udagawa A, Yoshimoto S, Ichinose M, Saito Y.
    • Journal Title

      Eur. J. Clin. Invest. 38

      Pages: 752-759

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592069
  • [Journal Article] A secreted soluble form of LR11, specifically expressed in intimal smooth muscle cells,accelerates formation of lipid-laden macrophages2007

    • Author(s)
      Ohwaki K, Bujo H, Jiang M, Yamazaki H, Schneider WJ, Saito Y.
    • Journal Title

      Arterioscler. Thromb. Vasc. Biol 27

      Pages: 1050-1056

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591036
  • [Journal Article] A Secreted Soluble Form of LR11, Specifically Expressed in Intimal Smooth Muscle Cells, Accelerates Formation of Lipid-Laden Macrophages.2007

    • Author(s)
      Ohwaki K, Bujo H, Jiang M, Yamazaki H, Schneider WJ, Saito Y
    • Journal Title

      Arterioscler Thromb Vasc Biol. (Published online)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] A secreted soluble form of LR11,specifically expressed in intimal smooth muscle cells,accelerates a formation of lipid-accumulated macrohaes2007

    • Author(s)
      Ohwaki K, Bujo H, Jiang M, Yamzaki H, Schneider WJ, Saito Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol 27(5)

      Pages: 1050-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591036
  • [Journal Article] A Secreted Soluble Form of LR11, Speciffically Expressed in Intimal Smooth Muscle Cells, Acclerates Formation of Lipid-Laden Macrophages.2007

    • Author(s)
      Ohwaki K, Bujo H, Jiang M, Yamazaki H, Schneider WJ, Saito Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol. Mar 1 (Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] A Selected Soluble Form of LR11, Specifically Expressed in Intimal Smooth Muscle Cells Accelerates Formation of Lipid - Laden Macrophages.2007

    • Author(s)
      Ohwaki K, Bujo H, Yamazaki H, Schneider WJ, Saito Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol. Published on line

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] Pitavastatin attenuates the PDGF-induced LR11/uPA receptor-mediated migration of smooth muscle cells.2006

    • Author(s)
      Jiang M, Bujo H, Zhu Y, Yamazaki H, Hirayama S, Kanaki T, Shibasaki M, Takahashi K, Schneider WJ, Saito Y
    • Journal Title

      Biochem Biophys Res Commun. 348(4)

      Pages: 1367-1377

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] Pitavastatin attnuate the PDGF-induced LR11/u PA receptor mediate migragion of smooth muscle cells.2006

    • Author(s)
      Jiang M, Bujo H, Zhu Y, Yamasaki H, Hirayama S, Kanakki T, Shibasaki M, Takahashi K, Schneid or WJ, Saito Y.
    • Journal Title

      Biochem Biophys Res Commun 348(4)

      Pages: 1367-1377

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] Modulation of smooth muscle cell migration by members of the low-density lipoprotein receptor family.2006

    • Author(s)
      Bujo H, Saito Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol. 26(6)

      Pages: 1246-1252

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] Modulation of smooth muscle cell migration by members of the low-density lipoprotein receptor family.2006

    • Author(s)
      Bujo H, Saito Y.
    • Journal Title

      Arterioscler Thomb Vasc Biol 26(6)

      Pages: 1246-1252

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] Implantation of primary cultured adipocytes that secrete Insulin modifies blood glucose levels in diabetic mice.2005

    • Author(s)
      Ito M, Bujo H, Takahashi K, Arai T, Tanaka I, Saito Y.
    • Journal Title

      Diabetologia 48(8)

      Pages: 1614-1620

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590869
  • [Journal Article] LRP1B is a negative modulator of increased migration activity of intimal smooth muscle cells from rabbit aortic plaques.2005

    • Author(s)
      Seki N, Bujo H, Jiang M, Tanaga K, Takahashi K, Yagui K, Hashimoto N, Schneider WJ, Saito Y
    • Journal Title

      Biochem Biophys Res Commun. 331(4)

      Pages: 964-970

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] Roles of degree of fat deposition and its localization on VEGF expression in adipocytes.2005

    • Author(s)
      Miyazawa-Hoshimoto S, Takahashi K, Bujo H, Hashimoto N, Yagui K, Saito Y
    • Journal Title

      Am J Physiol Endocrinol Metab. 288(6)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590869
  • [Journal Article] LRP1B is a negative modulator of increased migration activity of intimal smooth muscle cells from rabbit aortic plaques.2005

    • Author(s)
      Seki N, Bujo H, Tanaga K, Takahashi K, Yagui K, Hashimoto N, Schneider WJ, Saito Y.
    • Journal Title

      Biochem Biophys Res Commun 331(4)

      Pages: 964-970

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] Implantation of primary cultured adipocytes that secrete insulin modifies blood glucose levels in diabetic mice.2005

    • Author(s)
      Ito M, Bujo H, Takahashi K, Arai T, Tanaka I, Saito Y
    • Journal Title

      Diabetologia. 48(8)

      Pages: 1614-20

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590869
  • [Journal Article] LRP1B is a negative modulator of increased migration activity of intimal smooth muscle cells from rabbit aortic plaques.2005

    • Author(s)
      Seki N, Bujo H, Jiang M, Tanaga K, Takahashi K, Yagui K, Hashimoto N, Schneider WJ, _Saito_Y.
    • Journal Title

      Biochem Biophys Res Commun. 331(4)

      Pages: 964-970

    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] Roles of degree of fat deposition and its localization on VEGF expression in adipocytes.2005

    • Author(s)
      Miyazawa-Hoshimoto S, Takahashi K, Bujo H, Hashimoto N, Yagui K, Saito Y.
    • Journal Title

      Am J Physiol Endocrinol Metab 288(6)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590869
  • [Journal Article] Roles of degree of fat deposition and its localization on VEGF expression in adipocytes.2005

    • Author(s)
      Miyazawa-Hoshimoto S, Takahashi K, Bujo H, Hashimoto N, Yagui K, Saito Y.
    • Journal Title

      Am J Physiol Endocrinol Metab. 288(6)

    • Data Source
      KAKENHI-PROJECT-16590869
  • [Journal Article] A potent activator of PPARalpha and gamma reduces the vascular cell recruitment and inhibits the intimal thickning in hypercholesterolemic rabbits.2005

    • Author(s)
      Seki N, Bujo H, Jiang M, Shibasaki M, Takahashi K, Hashimoto N, Saito Y.
    • Journal Title

      Atherosclerosis. 178(1)

      Pages: 1-7

    • Data Source
      KAKENHI-PROJECT-17590917
  • [Journal Article] Implantation of primary cultured adipocytes that secrete insulin modifies blood glucose levels in diabetic mice.2005

    • Author(s)
      Ito M, Bujo H, Takahashi K, Arai T, Tanaka I, Saito Y.
    • Journal Title

      Diabetologia. 48(8)

      Pages: 1614-1620

    • Data Source
      KAKENHI-PROJECT-16590869
  • [Presentation] Familial Hypercholesterolemia Expert Forum (FAME)研究サブ解析2021

    • Author(s)
      1.小倉正恒, 斯波真理子, 増田大作, 荒井秀典, 武城英明, 石橋 俊, 代田浩之, 古賀伸彦, 及川眞一, 山下静也
    • Organizer
      第53回日本動脈硬化学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18K19526
  • [Presentation] 疾患マーカーとしての可溶性リポ蛋白受容体-脂肪細胞バイオマーカーの可能性-2020

    • Author(s)
      姜 美子, 武城英明
    • Organizer
      第52回日本動脈硬化学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18K19526
  • [Presentation] The LDL-receptor relative LR11 is an autonomous regulator of white-to-beige trans-differentiation in polymer-scaffold 3D-cultured adipocytes.2019

    • Author(s)
      Meizi Jiang, Tatsuro Kanaki, Akiteru Hayashi, Hiroyuki Ebinuma, Wolfgang J. Schneider, Hideaki Bujo
    • Organizer
      American Heart Association(AHA)Scientific Sessions 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19526
  • [Presentation] Expression of LR11/SorLA, a thermogenesis suppressor, is regulated in adipogenesis of cultured adipocytes2018

    • Author(s)
      Jiang M, Ebinuma H, Murano T, Bujo H
    • Organizer
      25th European Congress on Obesity
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05231
  • [Presentation] ベージュ脂肪は高脂肪摂取マウスの脂質異常を抑制する―脂肪の質を変える食事生活指導の可能性―2018

    • Author(s)
      姜 美子, Antonio Vidal-Puig, Monique T. Mulder, Wolfgang J.Schneider, 武城英明
    • Organizer
      第50回日本動脈硬化学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16H05231
  • [Presentation] Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans2017

    • Author(s)
      Meizi Jiang, Andrew J Whittle, Hiroyuki Ebinuma, Takeyoshi Murano, Chiaki Nakaseko, Wenlong Jin, Wolfgang J Schneider, Antonio Vidal-Puig & Hideaki Bujo
    • Organizer
      24th European Congress on Obesity (ECO/EASO)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05231
  • [Presentation] Identification of a regulator for energy expenditure in adipose tissues2016

    • Author(s)
      姜 美子、武城 英明
    • Organizer
      18th International Conference on Emerging Infectious Diseases (EID)
    • Place of Presentation
      ワシントンD.C.(アメリカ)
    • Year and Date
      2016-01-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461369
  • [Presentation] 濾胞性リンパ腫における可溶型LR11のバイオマーカーとしての有用性2013

    • Author(s)
      川口岳晴,大和田千桂子、山崎敦子、塚本祥吉、酒井紫緒、竹田勇輔、武内正博、堺田恵美子、清水直美、横手幸太郎、武城英明、中世古知昭.
    • Organizer
      第50回日本臨床分子医学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25461409
  • [Presentation] LR11 plays critical roles in leukemogenesis of AML by regulating cell adhesion and homing ability2013

    • Author(s)
      西居圭吾、中世古知昭、武内正博、清水直美、大和田千佳子、塚本祥吉、川口岳晴、姜美子、岩間厚志、武城英明
    • Organizer
      第75回日本血液学会総会
    • Year and Date
      2013-10-11
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] LR11 Plays a Critical Role in Leukemogenesis of Acute Myeloid Leukemia by Regulating Adhesion and Homing Ability to Bone Marrow2012

    • Author(s)
      西居圭吾、武内正博、中世古知昭、武城英明ほか
    • Organizer
      54th ASH annual meeting and exposition(米国血液学会年次総会)
    • Year and Date
      2012-12-09
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] LR11 regulates the hypoxia-induced hematopoietic immature cell adhesion2012

    • Author(s)
      西居圭吾、武内正博、中世古知昭、武城英明ほか
    • Organizer
      第74回日本血液学会総会
    • Year and Date
      2012-10-20
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] LR11 regulates the hypoxia-induced hematopoietic immature cell adhesion.2012

    • Author(s)
      西居圭吾、武内正博、中世古知昭、武城英明 ほか
    • Organizer
      日本血液学会総会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] Serum soluble LR11 is a promising novel biomarker for B cell lymphoma2012

    • Author(s)
      川口岳晴、大和田千桂子、酒井紫緒、竹田勇輔、清水直美、武内正博、堺田恵美子、田久保耕平、海老沼宏幸、深町勇、東守洋、田丸淳一、横手幸太郎、武城英明、中世古知昭
    • Organizer
      53rd ASH annual meeting and exposition(米国血液学会年次総会)
    • Year and Date
      2012-12-10
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] 可溶型LR11はCD87・CD11b複合体を介して単球系THP-1細胞を活性化する2011

    • Author(s)
      塚本祥吉、武内正博、杉田泰雅、山崎敦子、川口岳晴、酒井紫緒、竹田勇輔、 大和田千桂子、清水直美、堺田恵美子、西居圭吾、姜美子、横手幸太郎、武城 英明、中世古知昭
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] Serum soluble LR11 is a promising novel biomarker for B cell lymphoma.2011

    • Author(s)
      川口岳晴、 大和田千桂子、酒井紫緒、竹田勇輔、清水直美、武内正博、堺田恵美子、田久保耕平、海老沼宏幸、深町勇、東守洋、田丸淳一、横手幸太郎、武城 英明、中世古知昭
    • Organizer
      53rd ASH annual meeting and exposition (米国血液学会年次総会)
    • Place of Presentation
      サンディエゴ
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] Soluble LR11/SorLA, a Potential Circulating Marker Indicating the G-CSF-Induced Mobilization of Hematopoietic Stem Cells, Is a Modulator of G-CSF-Mediated Migration of HL-60 Cells2011

    • Author(s)
      清水直美、中世古知昭、武内正博、大和田千桂子、塚本祥吉、川口岳晴、西居桂吾、姜美子、横手幸太郎、深町勇、武城英明
    • Organizer
      53rd ASH annual meeting and exposition(米国血液学会年次総会)
    • Year and Date
      2011-12-12
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] 可溶型LR11はCD87・CD11b複合体を介して単球系THP-1細胞を活性化する2011

    • Author(s)
      塚本祥吉、武内正博、杉田泰雅、山崎敦子、川口岳晴、酒井紫緒、竹田勇輔、大和田千桂子、清水直美、堺田恵美子、西居圭吾、姜美子、横手幸太郎、武城英明、中世古知昭
    • Organizer
      第73回日本血液学会学術集会
    • Year and Date
      2011-10-15
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] 可溶性LR11は白血病細胞株HL-60の新たな走化性因子であり、G-CSFによる遊走能を増強する2011

    • Author(s)
      清水直美、中世古知昭、酒井紫緒、塚本祥吉、川口岳晴、竹田勇輔、大和田千桂子、武内正博、堺田恵美子、井関徹、西居桂吾、姜美子、横手幸太郎、武城英明
    • Organizer
      第73回日本血液学会学術集会
    • Year and Date
      2011-10-15
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] Serum soluble LR11 is a promising novel biomarker for malignant lymphoma2011

    • Author(s)
      川口岳晴、大和田千桂子、酒井紫緒、竹田勇輔、清水直美、武内正博、堺田恵美子、田久保耕平、海老沼宏幸、深町勇、東守洋、田丸淳一、横手幸太郎、武城英明、中世古知昭
    • Organizer
      第73回日本血液学会学術集会
    • Year and Date
      2011-10-15
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] 可溶性LR11は白血病細胞株HL-60の新たな走化性因子であり、G-CSFによる遊 走能を増強する2011

    • Author(s)
      清水直美、中世古知昭、酒井紫緒、塚本祥吉、川口岳晴、竹田 勇輔、大和田千桂子、武内正博、堺田恵美子、井関徹、西居桂吾、姜美子、横手幸太郎、武城英明
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] Serum soluble LR11 is a promising novel biomarker for malignant lymphoma.2011

    • Author(s)
      川口岳晴、 大和田千桂子、酒井紫緒、竹田勇輔、清水直美、武内正博、堺田恵美子、田久保耕平、海老沼宏幸、深町勇、東守洋、田丸淳一、横手幸太郎、武城 英明、中世古知昭
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] Soluble LR11/SorLA, a Potential Circulating Marker Indicating the G-CSF-Induced Mobilization of Hematopoietic Stem Cells, Is a Modulator of G-CSF-Mediated Migration of HL-60 Cells2011

    • Author(s)
      清水直美、中世古知昭、武内正博、大和田千桂子、塚本祥吉、川口岳晴、西居桂吾、姜美子、横手幸太郎、深町勇、武城英明
    • Organizer
      53rd ASH annual meeting and exposition (米国血液学会年次総会)
    • Place of Presentation
      サンディエゴ
    • Data Source
      KAKENHI-PROJECT-23591368
  • [Presentation] LR11 plays a critical role in leukemogenesis of AML by regulating cell adhes ion and homing ability

    • Author(s)
      西居桂吾、中世古知昭、武内正博、清水直美、大和田千桂子、塚本祥吉、川口岳晴、姜美子、岩間厚志 、武城英明
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23591368
  • 1.  SAITO Yasushi (50101358)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 29 results
  • 2.  UNOKI Hiroyuki (40323290)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 3.  NAKASEKO Chiaki (30323398)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 19 results
  • 4.  JIANG Meizi (00624066)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 5.  高橋 和男 (70334191)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  MORISAKI Nobuhiro (40174411)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  TAKEUCHI Masahiro (50466702)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 18 results
  • 8.  OHWADA Chikako (80436352)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 9.  SHIMIZU Naomi (30375802)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 10.  HIRUTA Nobuyuki (50201736)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 11.  RIKIHISA Naoaki (60436433)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 12.  ICHINOSE Masaharu (90082156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 13.  IWAMA Atsushi (70244126)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 14.  SHIRAI Kohji (00150269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MURANO Shunichi (50231634)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  NAGAO Tateki (20167555)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  IKEUCHI Takeshi (20372469)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KURODA Masayuki (00253005)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KUBOTA Yoshitaka (10375735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SAKAIDA Emiko (60422218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  HIGASHI Morihiko (00323395)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 22.  LINDSTEDT Ken
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  HARUNO Akihiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SCHUNEIDER W
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SCHNEIDER Wolfgang
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  LINDSTELT Ke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SCHNEIDER Wo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  Antonio Vidal-Puig
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  SATOH Kimio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  田丸 淳一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 31.  横手 幸太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  矢野 康次
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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