YUGAWA Takashi 温川恭至

… Alternative Names

温川恭至ユガワタカシ

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Researcher Number	80311372
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員
Affiliation (based on the past Project Information) *help	2015 – 2017: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員 2013 – 2014: 独立行政法人国立がん研究センター, 研究所, 主任研究員 2010 – 2012: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 研究所, 研究員 2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, ウイルス部, 研究員 2008: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, ウイルス部, 研究員 … More 2007: 国立がんセンター研究所及び東病院臨床開発センター, 研究所・ウイルス部, 研究員 2006: 国立がんセンター(研究所), ウイルス部, 研究員 2004: national cancer center research institute, virology division, Reseacher, ウイルス部, 研究員 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 分子腫瘍学 / p63 / 発現制御 / 悪性化 / 癌 / ｐ63 / Myc / Notch1 / MYC / 幹細胞性 … More / 細胞分化 / ゲノム傷害 / 転写調節 / がん抑制遺伝子 / 発がん … More Except Principal Investigator E7 / E6 / ヒトパピローマウイルス / 子宮頸がん / PDZ domain / telomerase / immkortalization / Cancer of uterine cervix / Human Papillomavirus / DLG4 / PSD95 / トランスフォーメーション / PDZドメイン / テロメラーゼ / 不死化 / E2F / DNA-PK / 組み込み / HPV Less

Molecular basis for the dual face of NOTCH1 in the development of squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  YUGAWA Takashi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Cancer Center Japan
Malignant conversion of epithelial cancers through dysregulation of the p63-MYC pathwayPrincipal Investigator
- Principal Investigator
  
  YUGAWA Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Center of Neurology and Psychiatry
Disruption of the p53-Notchl pathway in the development of human epithelial cancersPrincipal Investigator
- Principal Investigator
  
  YUGAWA Takashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
子宮頚がん発生におけるHPV DNAの組み込みとE6、E7発現増加機構の解明
- Principal Investigator
  
  KIYONO Tohru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
Analyzing mechanism of oncogenesis by human papillomavirus
- Principal Investigator
  
  KIYONO Tohru
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Research Institute

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Induction of non-apoptotic programmed cell death by oncogenic RAS in human epithelial cells and its suppression by MYC overexpression.2018
- Author(s)
  Dendo K, Yugawa T, Nakahara T, Ohno SI, Goshima N, Arakawa H, Kiyono T.
- Journal Title
  
  Carcinogenesis
  
  Volume: 39 Issue: 2 Pages: 202-213
- DOI
  10.1093/carcin/bgx124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04701, KAKENHI-PROJECT-26460406
[Journal Article] Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor.2017
- Author(s)
  Mori S, Takeuchi T, Ishii Y, Yugawa T, Kiyono T, Nishina H, Kukimoto I.
- Journal Title
  
  Journal of Virology
  
  Volume: 91 Issue: 6
- DOI
  10.1128/jvi.02413-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10740, KAKENHI-PROJECT-26460406, KAKENHI-PROJECT-26460564, KAKENHI-PUBLICLY-17H05996, KAKENHI-PROJECT-17H03982
[Journal Article] Roles of the PDZ-binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes.2017
- Author(s)
  Yoshimatsu Y, Nakahara T, Tanaka K, Inagawa Y, Narisawa-Saito M, Yugawa T, Ohno SI, Fujita M, Nakagama H, Kiyono T.
- Journal Title
  
  Cancer Science
  
  Volume: 108(7) Issue: 7 Pages: 1303-1309
- DOI
  10.1111/cas.13264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460406
[Journal Article] Activation of NF-κB by Human Papillomavirus 16 E1 Limits E1-Dependent Viral Replication through Degradation of E1.2015
- Author(s)
  Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T.
- Journal Title
  
  Journal of Virology
  
  Volume: 89 Issue: 9 Pages: 5040-5059
- DOI
  10.1128/jvi.00389-15
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860349, KAKENHI-PROJECT-26460406
[Journal Article] Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture.2015
- Author(s)
  Sugimoto N, Maehara K, Yoshida K, Yasukouchi S, Osano S, Watanabe S, Aizawa M, Yugawa T, et al.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 43 Issue: 12 Pages: 5898-5911
- DOI
  10.1093/nar/gkv509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460406, KAKENHI-PROJECT-15K18412, KAKENHI-PLANNED-25116010, KAKENHI-PUBLICLY-26114713, KAKENHI-PROJECT-25291027, KAKENHI-PROJECT-26290064
[Journal Article] ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication.2014
- Author(s)
  Iwahori S, Kohmon D, Kobayashi J, Tani Y, Yugawa T, Komatsu K, Kiyono T, Sugimoto N, Fujita M.
- Journal Title
  
  Cell Cycle
  
  Volume: 13 Issue: 3 Pages: 471-481
- DOI
  10.4161/cc.27274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-23590375, KAKENHI-PROJECT-24310041, KAKENHI-PROJECT-24650622, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25291027, KAKENHI-PROJECT-25550025, KAKENHI-PROJECT-25870509, KAKENHI-PUBLICLY-26114713, KAKENHI-PROJECT-26550025
[Journal Article] A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.2014
- Author(s)
  Inagawa Y, Yamada K, Yugawa T, Ohno SI, Hiraoka N, Esaki M, Shibata T, Aoki K, Saya H and Kiyono T
- Journal Title
  
  Carcinogenesis
  
  Volume: 35 Issue: 8 Pages: 1840-1846
- DOI
  10.1093/carcin/bgu112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-26460406
[Journal Article] Noncanonical NOTCH signaling limits self-renewal of human epithelial and induced pluripotent stem cells through ROCK activation.2013
- Author(s)
  Yugawa T, Nishino K, Ohno S, Nakahara T, Fujita M, Goshima N, Umezawa A, Kiyono T
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 33(22) Issue: 22 Pages: 4434-4447
- DOI
  10.1128/mcb.00577-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590375, KAKENHI-PROJECT-23590908, KAKENHI-PROJECT-24650622, KAKENHI-PROJECT-25291027, KAKENHI-PROJECT-25860349
[Journal Article] Heterocomplex Formation by Arp4 and β-Actin Involved in Integrity of the Brg1 Chromatin Remodeling Complex2012
- Author(s)
  Nishimoto, N.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 125 Pages: 3870-3882
- DOI
  10.1242/jcs.104349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510061, KAKENHI-PROJECT-23590375, KAKENHI-PROJECT-24650622, KAKENHI-PLANNED-22131004
[Journal Article] A critical role of MYC for transformation of human cells by HPV16 E6E7 and oncogenic HRAS2012
- Author(s)
  Narisawa-Saito, M.
- Journal Title
  
  Carcinogenesis
  
  Volume: 33 Issue: 4 Pages: 910-917
- DOI
  10.1093/carcin/bgs104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300345, KAKENHI-PROJECT-23590375, KAKENHI-PROJECT-23791303, KAKENHI-PROJECT-24650622, KAKENHI-PUBLICLY-23114510
[Journal Article] The E1 protein of human papillomavirus type 16 is dispensable for maintenance replication of the viral genome2012
- Author(s)
  Egawa, N., et al
- Journal Title
  
  J.Virol.
  
  Volume: 86 Issue: 6 Pages: 3276-3281
- DOI
  10.1128/jvi.06450-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370084, KAKENHI-PROJECT-22592084, KAKENHI-PUBLICLY-23114510, KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-23590375, KAKENHI-PROJECT-23790517, KAKENHI-PROJECT-23791303, KAKENHI-PROJECT-24650622
[Journal Article] Chromatin remodeler sucrose nonfermenting 2 homolog (SNF2H) is recruited onto DNA replication origins through interaction with Cdc10 protein-dependent transcript 1 (Cdt1) and promotes pre-replication complex formation2011
- Author(s)
  Nozomi Sugimoto
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 286 Issue: 45 Pages: 39200-39210
- DOI
  10.1074/jbc.m111.256123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J07233, KAKENHI-PROJECT-21370084, KAKENHI-PROJECT-22590276, KAKENHI-PROJECT-23590375
[Journal Article] An in vitro multistep carcinogenesis model for both HPV-positive and -negative human oral squamous cell carcinomas2011
- Author(s)
  Zushi Y, Narisawa-Saito M, Noguchi K, Yoshimatsu Y, Yugawa T, Egawa N, Fujita M, Urade M, Kiyono T
- Journal Title
  
  Am J Cancer Res
  
  Volume: 1(7) Pages: 869-881
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196285/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590375
[Journal Article] DeltaNp63alpha repression of the Notchl gene supports the proliferative capacity of normal human keratinocytes and cervical cancer cells.2010
- Author(s)
  Yugawa T, Narisawa-Saito M, Yoshimatsu Y, Haga K, Ohno S, Egawa N, Fujita M, Kiyono T.
- Journal Title
  
  Cancer Res. 70(10)
  
  Pages: 4034-4044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790265
[Journal Article] DeltaNp63alpha repression of the Notch1 gene supports the proliferative capacity of normal human keratinocytes and cervical cancer cells.2010
- Author(s)
  温川恭至
- Journal Title
  
  Cancer Research
  
  Volume: 70(10) Pages: 4034-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790265
[Journal Article] Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses : novel functions of E6 and E7 oncoproteins.2009
- Author(s)
  Yugawa T, et al.
- Journal Title
  
  Reviews in Medical Virology 19(2)
  
  Pages: 97-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790265
[Journal Article] Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses: novel functions of E6 and E7 oncoproteins.2009
- Author(s)
  Yugawa T, Kiyono T.
- Journal Title
  
  Rev Med Virol. 19(2)
  
  Pages: 97-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790265
[Journal Article] Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.2009
- Author(s)
  Sasaki R, Narisawa-Saito M, Yugawa T, Fujita M, Tashiro H, Katabuchi H, Kiyono T.
- Journal Title
  
  Carcinogenesis. 30(3)
  
  Pages: 423-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790265
[Journal Article] Molecular basis of cervical carcinogenesis by high-risk human papillomaviruses2008
- Author(s)
  Yugawa T, et al.
- Journal Title
  
  Uirus 58(2)
  
  Pages: 141-54
- NAID
  10023888279
- Data Source
  KAKENHI-PROJECT-20790265
[Journal Article] Molecular basis of cervical carcinogenesis by high-risk human papillomaviruses.2008
- Author(s)
  Yugawa T, Kiyono T.
- Journal Title
  
  Uirusu. 58(2)
  
  Pages: 141-154
- NAID
  10023888279
- Data Source
  KAKENHI-PROJECT-20790265
[Journal Article] An in vitro multistep carcinogenesis model for human cervical cancer.2008
- Author(s)
  Narisawa-Saito M, Yoshimatsu Y, Ohno S, Yugawa T, Egawa N, Fujita M, Hirohashi S, Kiyono T.
- Journal Title
  
  Cancer Res. 68(14)
  
  Pages: 5699-5705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790265
[Journal Article] Regulation of Notchl gene expression by p53 in epithelial cells2007
- Author(s)
  Yugawa T, et. al.
- Journal Title
  
  Mol Cell Biol 27
  
  Pages: 3732-3742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012051
[Journal Article] Regulation of Notch1 gene expression by p53 in epithelial cells.
- Author(s)
  Yugawa T et al.
- Journal Title
  
  Mol Cell Biol (In press)
- Data Source
  KAKENHI-PROJECT-18012051
[Presentation] Non-canonical NOTCH signaling drives malignant progression of squamous cell carcinoma.2017
- Author(s)
  温川恭至, 中原知美, 藤田雅俊, 清野透
- Organizer
  第40回日本分子生物学会・生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-26460406
[Presentation] Dual roles of p63 and NOTCH1 in the development and progression of squamous cell carcinoma.2017
- Author(s)
  温川恭至, 中原知美, 藤田雅俊, 清野透
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26460406
[Presentation] The dual role of p63 in the development of squamous cell carcinoma.2016
- Author(s)
  温川恭至
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26460406
[Presentation] Loss of p63 in MYC-overexpressing cells can trigger malignant conversion through the NOTCH-ROCK pathway.2015
- Author(s)
  温川恭至
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460406
[Presentation] Non-canonical NOTCH signaling activates ROCK to control cellular differentiation.2014
- Author(s)
  温川恭至
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26460406
[Presentation] The novel NOTCH-ROCK pathway limits self-renewal of human epithelial and iPS cells.2014
- Author(s)
  温川恭至
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26460406
[Presentation] 非古典的NOTCHシグナリングによるROCKの活性化と角化細胞分化2013
- Author(s)
  温川恭至
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590375
[Presentation] Non-canonical NOTCH signaling integrates into ROCK activation to induce differentiation of human keratinocytes.(非古典的NOTCHシグナリングによるROCKの活性化と角化細胞分化)2013
- Author(s)
  温川恭至, 大野真一, 中原知美, 藤田雅俊, 五島直樹, 清野透
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜(口演)
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-23590375
[Presentation] Molecular mechanisms dictating the biological outcome of p63 loss in human keratinocytes.2013
- Author(s)
  Yugawa T
- Organizer
  The 6th International p63/p73 Workshop
- Place of Presentation
  Kazusa Akademia Park
- Invited
- Data Source
  KAKENHI-PROJECT-23590375
[Presentation] Molecular mechanisms dictating the biological outcome of p63 loss in human keratinocytes2013
- Author(s)
  Yugawa T, Kiyono T
- Organizer
  The 6th International p63/p73 Workshop
- Place of Presentation
  Kazusa Akademia Park
- Year and Date
  2013-09-17
- Invited
- Data Source
  KAKENHI-PROJECT-23590375
[Presentation] Non-canonical NOTCH signaling limits self-renewal of human keratinocytes through ROCK activation.(非古典的NOTCHシグナルはROCKの活性化を介して角化細胞の自己複製能を制限する)2013
- Author(s)
  温川恭至, 大野真一, 中原知美, 藤田雅俊, 五島直樹, 清野透
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸(示説発表)
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PROJECT-23590375
[Presentation] 非古典的NOTCHシグナルはROCKの活性化を介して角化細胞の自己複製能を制限する2013
- Author(s)
  温川恭至
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル
- Data Source
  KAKENHI-PROJECT-23590375
[Presentation] Dysregulation of the p63-MYC pathway in the development of squamous cell carcinomas.(扁平上皮がん発生におけるp63-MYC経路の異常)2012
- Author(s)
  温川恭至, 藤田雅俊, 清野透
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌(口演)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23590375
[Presentation] 扁平上皮がん発生におけるp63-MYC経路の異常2012
- Author(s)
  温川恭至
- Organizer
  第７１回日本癌学会学術総会
- Place of Presentation
  さっぽろ芸文館
- Data Source
  KAKENHI-PROJECT-23590375
[Presentation] Regulation of Notch1 gene expression by p53 family members and its disruption by HPV-16 E62011
- Author(s)
  Yugawa T, Kiyono T
- Organizer
  ICGEB (International Centre for Genetic Engineering and Biotechnology) DNA Tumour Virus Meeting
- Place of Presentation
  Trieste, Italy(口演)
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-23590375
[Presentation] -MYC over-expression cancels the proliferative defect triggered by p63 loss in keratinocytes.(c-MYCの過剰発現はp63欠損による角化細胞増殖能の喪失を回避する)2011
- Author(s)
  温川恭至, 藤田雅俊, 清野透
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋(示設発表)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23590375
[Presentation] p63 supports proliferation of normal keratinocytes and cervical cancer cells via Notch1 repression.2010
- Author(s)
  温川恭至
- Organizer
  The 26^<th> International Papillomavirus Conference
- Place of Presentation
  モントリオール、カナダ
- Year and Date
  2010-07-05
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] 高リスク型ヒトパピローマウイルスによる発がんの分子機構:E6の機能的役割2010
- Author(s)
  温川恭至、齋藤真子、藤田雅俊、清野透
- Organizer
  日本ウイルス学会学術集会シンポジウム2010年Regulation of Notchl gene expression by p53 family members and its disruption in cancer第69回日本癌学会学術総会口演
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] p63 supports proliferation of normal keratinocytes and cervical cancer cells via Notchl repression.2010
- Author(s)
  Yugawa T, Narisawa-Saito M, Fujita M, Kiyono T
- Organizer
  The 26^<th> International Papillomavirus conference口演
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] 高リスク型ヒトパピローマウイルスによる発がんの分子機構:E6の機能的役割2010
- Author(s)
  温川恭至、齋藤真子、吉松有紀、稲川悠紀、藤田雅俊、清野透
- Organizer
  第58回日本ウイルス学会学術集会シンポジウム
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] 高リスク型ヒトパピローマウイルスによる発がんの分子機構:E6の機能的役割2010
- Author(s)
  温川恭至
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  あわぎんホール(徳島県郷土文化会館)
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] p53ファミリーによるNotch1発現制御の破綻とがん化2010
- Author(s)
  温川恭至
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] 16型ヒトパピローマウイルスE6による新規p53-Notch1経路の下方調節2009
- Author(s)
  温川恭至
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  東京都市センターホテル
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] p63はNotch1がん抑制遺伝子の発現抑制を介してヒト正常角化細胞とがん細胞の増殖能を維持する2009
- Author(s)
  温川恭至
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] Down-modulation of the p53-Notchl pathway by HPV-16 E6.2009
- Author(s)
  Yugawa T, Narisawa-Saito M, Fujita M, Kiyono T
- Organizer
  The 25^<th> International Papillomavirus conference口演
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] p63-mediated repression of Notchl supports the proliferative potential of normal human keratinocytes and cancer cells.2009
- Author(s)
  温川恭至、齋藤真子、吉松有紀、大野真一、藤田雅俊、清野透
- Organizer
  第68回日本癌学会学術総会口演
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] 16型ヒトパピローマウイルスE6による新規p53-Notch1経路の下方調節2009
- Author(s)
  温川恭至、齋藤真子、吉松有紀、大野真一、藤田雅俊、清野透
- Organizer
  第57回日本ウイルス学会学術集会口演
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] Down-regulation of the p53-Notch1 pathway by HPV-16 E62009
- Author(s)
  温川恭至
- Organizer
  The 25^<th> International Papillomavirus Conference
- Place of Presentation
  マルメ、スウェーデン
- Year and Date
  2009-05-13
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] DeltaNp63alphaによりNotch1がん抑制遺伝子の発現抑制2008
- Author(s)
  温川恭至
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] DeltaNp63alpha represses Notchl tumor suppressor gene in normal human keratinocytes.2008
- Author(s)
  温川恭至、齋藤真子、角田有紀、大野真一、藤田雅俊、清野透
- Organizer
  第67回日本癌学会学術総会口演
- Data Source
  KAKENHI-PROJECT-20790265
[Presentation] Down-regulation of Notchl tumor suppressor and inhibition of keratinocyte diffrentiation by HPV-16E62007
- Author(s)
  Yugawa T, et. al.
- Organizer
  24th International Papillomavirus Conference
- Place of Presentation
  北京
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-18012051
[Presentation] c-MYCの過剰発現はp63欠損による角化細胞増殖能の喪失を回避する
- Author(s)
  温川恭至
- Organizer
  第７０回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23590375

1. KIYONO Tohru (10186356)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. NARISAWA Mako (50283023)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YAMASHITA Yoriko (90303643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松本義久 (20302672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. DENDO Kasimi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. NAKAHARA Tomomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 小松賢志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 小林純也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 佐谷秀行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 森清一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YUGAWA Takashi 温川 恭至

温川 恭至 ユガワ タカシ

Research Projects

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Co-Researchers

Molecular basis for the dual face of NOTCH1 in the development of squamous cell carcinomaPrincipal Investigator

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Malignant conversion of epithelial cancers through dysregulation of the p63-MYC pathwayPrincipal Investigator

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Disruption of the p53-Notchl pathway in the development of human epithelial cancersPrincipal Investigator

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子宮頚がん発生におけるHPV DNAの組み込みとE6、E7発現増加機構の解明

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Analyzing mechanism of oncogenesis by human papillomavirus

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[Journal Article] Induction of non-apoptotic programmed cell death by oncogenic RAS in human epithelial cells and its suppression by MYC overexpression.2018

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[Journal Article] Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor.2017

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[Journal Article] Roles of the PDZ-binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes.2017

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[Journal Article] Activation of NF-κB by Human Papillomavirus 16 E1 Limits E1-Dependent Viral Replication through Degradation of E1.2015

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[Journal Article] Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture.2015

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[Journal Article] ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication.2014

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[Journal Article] A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.2014

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[Journal Article] Noncanonical NOTCH signaling limits self-renewal of human epithelial and induced pluripotent stem cells through ROCK activation.2013

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[Journal Article] Heterocomplex Formation by Arp4 and β-Actin Involved in Integrity of the Brg1 Chromatin Remodeling Complex2012

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YUGAWA Takashi 温川恭至

温川恭至ユガワタカシ