Nakada Kazuto 中田和人

… Alternative Names

NAKADA Kazuto 中田和人

中田和人ナカダカズト

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Researcher Number	80323244
Other IDs
External Links
Affiliation (Current)	2026: 筑波大学, 生命環境系, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 筑波大学, 生命環境系, 教授 2011 – 2018: 筑波大学, 生命環境系, 教授 2010: 筑波大学, 大学院・生命環境科学研究科, 准教授 2007: University of Tsukuba, 大学院・生命環境科学研究科, 准教授 2006: 筑波大学, 大学院生命環境科学研究科, 助教授 2005: 筑波大学, 大学院・生命環境科学研究科, 助教授 2001 – 2002: 筑波大学, 生物科学系, 講師
Review Section/Research Field	Principal Investigator Laboratory animal science / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 42040:Laboratory animal science-related / Cell biology / Laboratory animal science / Laboratory medicine / Cell biology Except Principal Investigator 遺伝
Keywords	Principal Investigator ミトコンドリアゲノム / 突然変異 / モデルマウス / ミトコンドリア / ミトコンドリア病 / ミトコンドリアDNA / エネルギー代謝 / 病態モデルマウス / ミトコンドリアゲノム変異 / エネルギー代謝異常 … More / エネルギー欠損 / ミトコンドリア呼吸機能異常 / 病原性突然変異 / 哺乳類 / 転写 / 複製 / 調節領域 / 細胞分化 / インスリンシグナル / 骨格筋 / エネルギー産生異常 / エネルギー産生不全 / ミトコンドリア遺伝子疾患 / 病態発症機構 / エネルギー代謝不全 / エネルギー欠乏 / 体細胞突然変異 / ミトコンドリア間相互作用 / 変異型mtDNA / ミトコンドリアゲノム(mtDNA) / ミトコンドリア呼吸機能 / 遺伝子治療 / 減数分裂 / 精子形成 / 不妊症 / 呼吸欠損 / 治療 / 呼吸不全 / 機能形態学 / チトクロムcオキシダーゼ / 生体機能利用 / ミトコンドリア病モデルマウス / ヒト培養細胞 / 遺伝的相補 / 相互作用 … More Except Principal Investigator スプレータス / mtDNA組み換え / ミトコンドリア間相互作用 / mtDNAノックアウトマウス / 大欠失型mtDNA / マウスmtDNA Less

Studies on replication-related bases in mouse mitochondrial DNAPrincipal Investigator
- Principal Investigator
  
  中田和人
- Project Period (FY)
  2025 – 2030
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  University of Tsukuba
Reverse genetic studies on mitochondrial DNA mutations in micePrincipal Investigator
- Principal Investigator
  
  Nakada Kazuto
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  University of Tsukuba
Reverse genetic studies on mitochondrial DNA with pathogenic mutations in micePrincipal Investigator
- Principal Investigator
  
  NAKADA Kazuto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Studies on skeletal muscle fiber-type specific responses to pathogenic mtDNAPrincipal Investigator
- Principal Investigator
  
  NAKADA Kazuto
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  University of Tsukuba
Studies on pathogeneses of mitochondrial DNA-based disordersPrincipal Investigator
- Principal Investigator
  
  NAKADA Kazuto
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Studies on tissue-specific dynamics of pathogenic mutant mitochondrial DNA in micePrincipal Investigator
- Principal Investigator
  
  NAKADA Kazuto
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
モデルマウスを用いたミトコンドリア病の出生前治療法の開発Principal Investigator
- Principal Investigator
  
  中田和人
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Tsukuba
ミトコンドリアDNA突然変異導入マウスを用いたミトコンドリアゲノムの基礎遺伝学
- Principal Investigator
  
  林純一
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  遺伝
- Research Institution
  University of Tsukuba
突然変異mtDNAを用いたミトコンドリア間機能的相互作用の証明Principal Investigator
- Principal Investigator
  
  中田和人
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  University of Tsukuba

[Book] 細胞生物学2012
- Author(s)
  沼田治、千葉智樹、中野賢太郎、中田和人
- Total Pages
  203
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] Endurance swimming exacerbates mitochondrial myopathy in mice with high mtDNA deletions2025
- Author(s)
  Hanada Sho、Ishikawa Kaori、Shirai Takanaga、Takemasa Tohru、Nakada Kazuto
- Journal Title
  
  Mitochondrion
  
  Volume: 81 Pages: 102010-102010
- DOI
  10.1016/j.mito.2025.102010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K23801
[Journal Article] Accumulation of mitochondrial DNA with a point mutation in tRNALeu(UUR) gene induces brain dysfunction in mice.2024
- Author(s)
  Ishikawa, K., Miyata, D., Hattori, S., Tani, H., Kuriyama, T., Wei, F. Y., Miyakawa, T., & Nakada, K.
- Journal Title
  
  Pharmacological research
  
  Volume: 208 Pages: 107374-107374
- DOI
  10.1016/j.phrs.2024.107374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-21H05258, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-24H00065, KAKENHI-PROJECT-23K23801, KAKENHI-PROJECT-23K14113
[Journal Article] Pearson syndrome-like anemia induced by accumulation of mutant mtDNA and anemia with imbalanced white blood cell lineages induced by Drp1 deletion in a murine model2022
- Author(s)
  Ishikawa Kaori、Honma Yo、Yoshimi Ayami、Katada Shun、Ishihara Takaya、Ishihara Naotada、Nakada Kazuto
- Journal Title
  
  Pharmacological Research
  
  Volume: 185 Pages: 106467-106467
- DOI
  10.1016/j.phrs.2022.106467
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06066, KAKENHI-PUBLICLY-21H00225, KAKENHI-PROJECT-23K23801
[Journal Article] Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNALeu(UUR) with a pathogenic A2748G mutation2022
- Author(s)
  Tani Haruna、Ishikawa Kaori、Tamashiro Hiroaki、Ogasawara Emi、Yasukawa Takehiro、Matsuda Shigeru、Shimizu Akinori、Kang Dongchon、Hayashi Jun-Ichi、Wei Fan-Yan、Nakada Kazuto
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 16 Pages: 9382-9396
- DOI
  10.1093/nar/gkac699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07127, KAKENHI-PLANNED-21H05265, KAKENHI-PROJECT-22KJ0156, KAKENHI-PUBLICLY-21H00225, KAKENHI-PROJECT-23K21370, KAKENHI-PROJECT-23K23801
[Journal Article] Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells.2019
- Author(s)
  Ishikawa K, Kobayashi K, Yamada A, Umehara M, Oka T, Nakada K.
- Journal Title
  
  PLoS ONE
  
  Volume: 14 Issue: 3 Pages: 0213283-0213283
- DOI
  10.1371/journal.pone.0213283
- NAID
  120007133505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-17H03676, KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-18K06203
[Journal Article] Acquired expression of mutant Mitofusin 2 causes progressive neurodegeneration and abnormal behavior.2019
- Author(s)
  Ishikawa K, Yamamoto S, Hattori S, Nishimura N, Tani H, Mito T, Matsumoto H, Miyakawa T, Nakada K.
- Journal Title
  
  J Neurosci
  
  Volume: 39 Pages: 1588-1604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04678
[Journal Article] Mito-mice∆ and mitochondrial DNA mutator mice as models of human osteoporosis caused not by aging but by hyperparathyroidism2018
- Author(s)
  Mito Takayuki、Tani Haruna、Suzuki Michiko、Ishikawa Kaori、Nakada Kazuto、Hayashi Jun-Ichi
- Journal Title
  
  Exp. Anim.
  
  Volume: 67 Issue: 4 Pages: 509-516
- DOI
  10.1538/expanim.18-0060
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06203, KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-18J20289, KAKENHI-PROJECT-16K18535
[Journal Article] Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal.2018
- Author(s)
  Tani H, Ohnishi S, Shitara H, Mito T, Yamaguchi M, Yonekawa H, Hashizume O, Ishikawa K, Nakada K, Hayashi JI.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 425-425
- DOI
  10.1038/s41598-017-18828-3
- NAID
  120007134501
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-16K19034, KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16K14719, KAKENHI-PROJECT-18K06203, KAKENHI-PROJECT-16H02463, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-18J20289
[Journal Article] RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity2017
- Author(s)
  Yoshizumi T, Imamura H, Taku T, Kuroki T, Kawaguchi A, Ishikawa K, Nakada K, Koshiba T
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 5379-5379
- DOI
  10.1038/s41598-017-05808-w
- NAID
  120007128833
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19561, KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16H05192, KAKENHI-PROJECT-17H03667, KAKENHI-PROJECT-15J04145, KAKENHI-PROJECT-16K14709, KAKENHI-PROJECT-16K14719, KAKENHI-PROJECT-17H03654
[Journal Article] Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage.2016
- Author(s)
  Suzuki T, Kanno SI, Abe T. et al
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 27 Issue: 7 Pages: 1-8
- DOI
  10.1681/asn.2015060623
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26340020, KAKENHI-PROJECT-26460331, KAKENHI-PROJECT-26860094, KAKENHI-PROJECT-15H06367, KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-26282153, KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-16K12925, KAKENHI-PROJECT-16K14719, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-26293031, KAKENHI-PROJECT-26305007
[Journal Article] 突然変異型ミトコンドリアゲノムを含有するモデルマウス2016
- Author(s)
  小笠原絵美、中田和人
- Journal Title
  
  医学のあゆみ
  
  Volume: 260 Pages: 73-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K14719
[Journal Article] 突然変異型ミトコンドリアゲノムを含有するモデルマウス2016
- Author(s)
  小笠原絵美、中田和人
- Journal Title
  
  医学のあゆみ
  
  Volume: 260 Pages: 73-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04678
[Journal Article] FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders2016
- Author(s)
  Lehtonen JM, et al.（Nakada Kは24名中22番目の著者）
- Journal Title
  
  Neurology
  
  Volume: 87 Issue: 22 Pages: 2290-2299
- DOI
  10.1212/wnl.0000000000003374
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16K14719
[Journal Article] A novel mutation in TAZ causes mitochondrial respiratory chain disorder without cardiomyopathy2016
- Author(s)
  Borna NN, Kishita Y, Ishikawa K, Nakada K, Hayashi JI, Tokuzawa Y, Kohda M, Nyuzuki H, Yamashita-Sugahara Y, Nasu T, Takeda A, Murayama K, Ohtake A, Okazaki Y
- Journal Title
  
  J Hum Genet
  
  Volume: 62 Issue: 5 Pages: 539-547
- DOI
  10.1038/jhg.2016.165
- NAID
  40021210340
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16K14719, KAKENHI-PROJECT-16K09973, KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-16H02463, KAKENHI-PROJECT-15K09679
[Journal Article] A Novel MitoNEET Ligand, TT01001, Improves Diabetes and Ameliorates Mitochondrial Function in db/db Mice2015
- Author(s)
  Takehiro Takahashi, Masashi Yamamoto, Kazutoshi Amikura, Kozue Kato, Takashi Serizawa,Kanako Serizawa, Daisuke Akazawa, Takumi Aoki, Koji Kawai, Emi Ogasawara, Jun-Ichi Hayashi, Kazuto Nakada, and Mie Kainoh
- Journal Title
  
  J. Pharmacol. Exp. Ther.
  
  Volume: 352 Issue: 2 Pages: 338-345
- DOI
  10.1124/jpet.114.220673
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011
[Journal Article] G7731A mutation in mouse mitochondrial tRNALys regulates late-onset disorders in transmitochondrial mice.2015
- Author(s)
  Shimizu A, Mito T, Hashizume O, Yonekawa H, Ishikawa K, Nakada K, Hayashi J-I
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 459 Issue: 1 Pages: 66-70
- DOI
  10.1016/j.bbrc.2015.02.070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J00467, KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-25640057, KAKENHI-PROJECT-25290038
[Journal Article] A somatic T15091C mutation in the Cytb gene of mouse mitochondrial DNA dominantly induces respiration defects.2015
- Author(s)
  Hayashi C, Takibuchi G, Shimizu A, Mito T, Ishikawa K, Nakada K, Hayashi JI
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 463 Issue: 4 Pages: 1021-1027
- DOI
  10.1016/j.bbrc.2015.06.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-14J00467
[Journal Article] Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects2015
- Author(s)
  Hashizume O, Ohnishi S, Mito T, Shimizu A, Ishikawa K, Nakada K, Soda M, Mano H, Togayachi S, Miyoshi H, Okita K, Hayashi J
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 10434-10434
- DOI
  10.1038/srep10434
- NAID
  120005819481
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461155, KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-15H06367, KAKENHI-PROJECT-14J00467
[Journal Article] Mouse somatic mutation orthologous to MELAS A3302G mutation in the mitochondrial tRNA(Leu(UUR)) gene confers respiration defects.2015
- Author(s)
  Shimizu A, Enoki S, Ishikawa K, Mito T, Obata K, Nagashima R, Yonekawa H, Nakada K, Hayashi J.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 467 Issue: 4 Pages: 1097-102
- DOI
  10.1016/j.bbrc.2015.09.072
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-14J00467, KAKENHI-PROJECT-25290038
[Journal Article] Transmitochondrial mito-miceΔ and mtDNA mutator mice, but not aged mice, share the same spectrum of musculoskeletal disorders.2015
- Author(s)
  Mito T, Ishizaki H, Suzuki M, Morishima H, Ota A, Ishikawa K, Nakada K, Maeno A, Shiroishi T, Hayashi J-I
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 456 Issue: 4 Pages: 933-937
- DOI
  10.1016/j.bbrc.2014.12.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J00467, KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011
[Journal Article] A Specific Nuclear DNA Background Is Required for High Frequency Lymphoma Development in Transmitochondrial Mice with G13997A mtDNA2015
- Author(s)
  Osamu Hashizume, Haruka Yamanashi, Makoto M. Taketo, Kazuto Nakada, and Jun-Ichi Hayashi
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 3 Pages: e0118561-e0118561
- DOI
  10.1371/journal.pone.0118561
- NAID
  120007130305
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011
[Journal Article] Selection of rodent species appropriate for mtDNA transfer to generate transmitochondrial mito-mice expressing mitochondrial respiration defects.2014
- Author(s)
  Enoki S, Shimizu A, Hayashi C, Imanishi H, Hashizume O, Mekada K, Suzuki H, Hashimoto T, Nakada K, Hayashi J
- Journal Title
  
  Exp Anim
  
  Volume: 63 Pages: 21-30
- NAID
  130003391604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240058
[Journal Article] Administration of an Antioxidant Prevents Lymphoma Development in Transmitochondrial Mice Overproducing Reactive Oxygen Species2014
- Author(s)
  Haruka Yamanashi, Osamu Hashizume, Hiromichi Yonekawa, Kazuto Nakada, and Jun-Ichi Hayashi
- Journal Title
  
  Exp. Anim.
  
  Volume: 63 Pages: 459-466
- NAID
  130004701643
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23240058
[Journal Article] Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene.2014
- Author(s)
  Shimizu A, Mito T, Hayashi C, Ogasawara E, Koba R, Negishi I, Takenaga K, Nakada K, Hayashi J
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 111 Issue: 8 Pages: 3104-3109
- DOI
  10.1073/pnas.1318109111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240058, KAKENHI-PUBLICLY-24117503, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-25430110
[Journal Article] Specific mtDNA mutations in mouse carcinoma cells suppress their tumor formation via activation of the host innate immune system.2013
- Author(s)
  Imanishi H, Takibuchi G, Kobayashi T, Ishikawa K, Nakada K, Mori M, Kikkawa Y, Takenaga K, Toyama-Sorimachi N, Hayashi J
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 9 Pages: e75981-e75981
- DOI
  10.1371/journal.pone.0075981
- NAID
  120007136806
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240058, KAKENHI-PUBLICLY-24117503, KAKENHI-PROJECT-24500487, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-25430110, KAKENHI-PROJECT-25871165
[Journal Article] Polymorphic mutations in mouse mitochondrial DNA regulate a tumor phenotype.2013
- Author(s)
  Takibuchi G, Imanishi H, Morimoto M, Ishikawa K, Nakada K, Toyama-Sorimachi N, Kikkawa Y, Takenaga K, Hayashi J
- Journal Title
  
  Mitochondrion
  
  Volume: 13 Issue: 6 Pages: 881-887
- DOI
  10.1016/j.mito.2013.07.117
- NAID
  120007130592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240058, KAKENHI-PUBLICLY-24117503, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-25430110
[Journal Article] Mitochondrial DNA mutations in mutator mice confer respiration defects and B-cell lymphoma development.2013
- Author(s)
  Takayuki Mito, Yoshiaki Kikkawa, Akinori Shimizu, Osamu Hashizume, Shun Katada, Hirotake Tmaniahi Azusa Ota, Yukina Kato, Kazuto Nakada, Jun-Ichi Hayashi.
- Journal Title
  
  PLoS One
  
  Volume: 8(2) Issue: 2 Pages: e55789-e55789
- DOI
  10.1371/journal.pone.0055789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J01336, KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-23240058, KAKENHI-PUBLICLY-24117503
[Journal Article] Mitochondrial DNA with a large-scale deletion causes two distinct mitochondrial disease phenotypes in mice.2013
- Author(s)
  Katada S, Mito T, Ogasawara E, Hayashi J, Nakada K
- Journal Title
  
  G3 (Bethesda)
  
  Volume: 3 Issue: 9 Pages: 1545-1552
- DOI
  10.1534/g3.113.007245
- NAID
  120007136822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240058, KAKENHI-PUBLICLY-24117503, KAKENHI-PROJECT-25250011
[Journal Article] Comprehensive application of an mtDsRed2-Tg mouse strain for mitochondrial imaging2012
- Author(s)
  Yamaguchi, J., Nishiyama, S., Shimanuki, M., Ono, T., Sato, A., Nakada, K., Hayashi, J-I., Yonekawa, H., Shitara, H
- Journal Title
  
  Transgenic Research
  
  Volume: 21巻 Issue: 2 Pages: 439-447
- DOI
  10.1007/s11248-011-9539-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240044, KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-22680035, KAKENHI-PROJECT-24700442
[Journal Article] Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development2012
- Author(s)
  Hashizume O, Shimizu A, Yokota M, Sugiyama A, Nakada K, Miyoshi H, Itami M, Ohira M, Nagase H, Takenaga K, Hayashi J.
- Journal Title
  
  Proc Natl Acad Sci USA.
  
  Volume: 109(26) Issue: 26 Pages: 10528-33
- DOI
  10.1073/pnas.1202367109
- NAID
  120007137266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-23300344, KAKENHI-PUBLICLY-24117503
[Journal Article] Mitochondrial DNA mutations regulate metastasis of human breast cancer cells2011
- Author(s)
  Imanishi H, Hattori K, Wada R, Ishikawa K, Fukuda S, Takenaga K, Nakada K, Hayashi J
- Journal Title
  
  PLoS One
  
  Volume: 6(8) Issue: 8 Pages: e23401-e23401
- DOI
  10.1371/journal.pone.0023401
- NAID
  120007137464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] Transmitochondrial mice as models for mitochondrial DNA-based diseases2011
- Author(s)
  Nakada, K.
- Journal Title
  
  Experimental Animals
  
  Volume: 60 Pages: 421-431
- NAID
  10029835173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells2011
- Author(s)
  Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, Watanabe S, Ando J, Iwadate M, Yamamoto M, Lee MS, Tanaka K, Komatsu M
- Journal Title
  
  J Cell Biol
  
  Volume: 193 Issue: 2 Pages: 275-284
- DOI
  10.1083/jcb.201102031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21390234, KAKENHI-PROJECT-21659045, KAKENHI-PROJECT-22650091
[Journal Article] Transmitochondrial mice as models for mitochondrial DNA-based diseases2011
- Author(s)
  Nakada, K.
- Journal Title
  
  Experimental Animals
  
  Volume: 60 Pages: 421-431
- NAID
  10029835173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240058
[Journal Article] Nuclear but not mitochondrial DNA involvement in respiratory complex I defects found in senescence-accelerated mouse strain2011
- Author(s)
  Imanishi H, Yokota M, Mori M, Shimizu A, Nakada K, Hayashi J
- Journal Title
  
  SAMP8.Exp Anim
  
  Volume: 60(4) Pages: 397-404
- URL
  http://dx.doi.org/10.1538/expanim.60.397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] Transmitochondrial mice as models for mitochondrial DNA-based diseases.Exp Anim2011
- Author(s)
  Nakada K, Hayashi J
- Journal Title
  
  Exp Anim
  
  Volume: 60(5) Pages: 421-31
- URL
  http://dx.doi.org/10.1538/expanim.60.421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] The innate immune system in host mice targets cells with allogenic mitochondrial DNA2010
- Author(s)
  Ishikawa K, Toyama-Sorimachi N, Nakada K, Morimoto M, Imanishi H, Yoshizaki M, Sasawatari S, Niikura M, Takenaga K, Yonekawa H, Hayashi J
- Journal Title
  
  J Exp Med
  
  Volume: 207(11) Issue: 11 Pages: 2297-305
- DOI
  10.1084/jem.20092296
- NAID
  120007137786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells2010
- Author(s)
  Yokota, M., Shitara, H., Hashizume, O., Ishikawa, K., Nakada, K., Ishii, R., Taya, C., Takenaga, K., Yonekawa, H., Hayashi, J
- Journal Title
  
  FEBS letters
  
  Volume: 584巻 Issue: 18 Pages: 3943-3948
- DOI
  10.1016/j.febslet.2010.07.048
- NAID
  120007137913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240044, KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-22680035
[Journal Article] Lactic acidemia in the pathogenesis of mice carrying mitochondrial DNA with a deletion2010
- Author(s)
  Emi Ogasawara, Kazuto Nakada Jun-Ichi Hayashi
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 19 Pages: 3179-3189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] Lactic acidemia in the pathogenesis of mice carrying mitochondrial DNA with a deletion2010
- Author(s)
  Ogasawara E, Nakada K, Hayashi J
- Journal Title
  
  Hum Mol Genet
  
  Volume: 19(16) Issue: 16 Pages: 3179-89
- DOI
  10.1093/hmg/ddq228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells2010
- Author(s)
  Inoue S, Noda S, Kashima K, Nakada K, Hayashi J, Miyoshi H
- Journal Title
  
  FEBS Lett
  
  Volume: 584(15) Issue: 15 Pages: 3402-9
- DOI
  10.1016/j.febslet.2010.06.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] ミトコンドリアセントラルドグマの破綻病理2010
- Author(s)
  中田和人, 石川香, 林純一
- Journal Title
  
  細胞工学
  
  Volume: 29 Pages: 466-473
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] Over-expression of Tfam improves the mitochondrial disease phenotypes in a mouse model system2010
- Author(s)
  Nishiyama, S., Shitara, H., Nakada, K., Ono, T., Sato, A., Suzuki, H., Ogawa, T., Masaki, H., Hayashi, J-I., Yonekawa, H
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 401巻 Issue: 1 Pages: 26-31
- DOI
  10.1016/j.bbrc.2010.08.143
- NAID
  120007137866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240044, KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-22680035
[Journal Article] p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria2010
- Author(s)
  Okatsu K, Saisho K, Shimanuki M, Nakada K, Shitara H, Sou YS, Kimura M, Sato S, Hattori N, Komatsu M, Tanaka K, Matsuda N
- Journal Title
  
  Genes Cells
  
  Volume: 15(8) Issue: 8 Pages: 887-900
- DOI
  10.1111/j.1365-2443.2010.01426.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650091
[Journal Article] Deletion-mutant mtDNA increases in somatic tissues but desreases in temal germcells with age2007
- Author(s)
  Sato A, Nakada K, Shitara H, Kasahara A, Yonekawa H, Hayashi JI
- Journal Title
  
  Genetics 117
  
  Pages: 2031-2037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689023
[Journal Article] Direct cloning of full-length mouse mitochondrial DNA using a Bacillussubtilis genome2007
- Author(s)
  Yonermurar I, Nakada K, Sato A, Hayashi JI Fujita K, Kaneko S, .Itaya M
- Journal Title
  
  Genetics 391
  
  Pages: 171-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689023
[Journal Article] Pategenic mitochondrial DNA-induced respiration defects in hematopedetic cells resuit in anemia by suppressing erythroid difirerentiatient2007
- Author(s)
  Inoue SI, Yokota M, Nakada K, Miyoshi H, Hayshi JI
- Journal Title
  
  FEBS Lett 581
  
  Pages: 1910-1916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689023
[Journal Article] Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells.2006
- Author(s)
  A Kasahara, K Ishikawa, M Yamaoka, M Ito, N Watanabe, M Akimoto, A Sato, K Nakada, H Endo, Y Suda, S-I Aizawa, J-I Hayashi
- Journal Title
  
  Hum.Mol.Genet. 15巻6合
  
  Pages: 871-881
- Data Source
  KAKENHI-PROJECT-17689023
[Journal Article] Mitochondrial dynamics and aging : Mitochondrial interaction preventing individuals from expression of respiratory deficiency caused by mutant mtDNA2006
- Author(s)
  A Sato, K Nakada, J-I Hayashi
- Journal Title
  
  Biochim.Biophys.Acta. 1763
  
  Pages: 473-481
- Data Source
  KAKENHI-PROJECT-17689023
[Journal Article] Suppression of disease phenotypes of adult mito-mice carrying pathogenic mtDNA by bone marrow transplantation2006
- Author(s)
  S-I Inoue, K Ishikawa, K Nakada, A Sato, H Miyoshi, J-I Hayashi
- Journal Title
  
  Hum.Mol.Genet. 15
  
  Pages: 1801-1807
- Data Source
  KAKENHI-PROJECT-17689023
[Journal Article] Mitochondria-related male infertility2006
- Author(s)
  K Nakada, A Sato, K Yoshida, T Morita, H Tanaka, S-I Inoue, H Yonekawa, J-I Hayashi
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103
  
  Pages: 15148-15153
- Data Source
  KAKENHI-PROJECT-17689023
[Journal Article] ミトコンドリアゲノム突然変異に起因する男性不妊2006
- Author(s)
  中田和人
- Journal Title
  
  医学のあゆみ
- Data Source
  KAKENHI-PROJECT-17689023
[Journal Article] Application of ES cells for generation of respiration-deficient mice carrying mtDNA with a large-scale deletion.2005
- Author(s)
  K Ishikawa, A Kasahara, N Watanabe, K Nakada, A Sato, Y Suda, S-I Aizawa, J-I Hayashi
- Journal Title
  
  Biochem.Biophys.Res.Commun. 333巻2号
  
  Pages: 590-595
- Data Source
  KAKENHI-PROJECT-17689023
[Journal Article] Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation.2005
- Author(s)
  A Sato, T Kono, K Nakada, Ishikawa, S-I Inoue, H Yonekawa, J-I Hayashi
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 102巻46号
  
  Pages: 16765-16770
- Data Source
  KAKENHI-PROJECT-17689023
[Journal Article] Rare creation of recombinant mtDNA hapolotypes in mammalian tissures.2005
- Author(s)
  A Sato, K Nakada, M Akimoto, K Ishikawa, T Ono, H Shitara, H Yonekawa, J-I Hayashi
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 102巻17号
  
  Pages: 6057-6062
- Data Source
  KAKENHI-PROJECT-17689023
[Patent] ミトコンドリア機能活性化物質のスクリーニング方法2006
- Inventor(s)
  中田和人他3名
- Industrial Property Rights Holder
  筑波大学
- Industrial Property Number
  2006-101728
- Filing Date
  2006-04-03
- Data Source
  KAKENHI-PROJECT-17689023
[Presentation] 加齢に伴う変異型ミトコンドリアDNAの遺伝様式の変化2025
- Author(s)
  石川香; 伊藤香菜子; 佐々木悠馬; 安原菜々子; 樋口智佳; 林克彦; 中田和人
- Organizer
  第130回日本解剖学会/第102回日本生理学会/第98回日本薬理学会合同大会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] ミトコンドリアDNA突然変異よるがん悪性化の検証2024
- Author(s)
  齊藤さくら; 中田和人; 石川香
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] ミトコンドリア機能異常に対する有酸素運動のパラドックス2024
- Author(s)
  花田翔; 白井隆長; 石川香; 武政徹; 中田和人
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] 老化モデルマウスにおいてミトコンドリア呼吸機能低下が筋線維組成に与える影響2024
- Author(s)
  玉城　大敬; 石川香; 中田和人
- Organizer
  第23回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] 加齢に伴う変異型ミトコンドリアDNAの生殖系列からの消失機構の解明を目指して2024
- Author(s)
  石川香; 伊藤香菜子; 佐々木悠馬; 安原菜々子; 中田和人
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] 新たなマイクロシンテニーとしての活用：Nuclear-mitochondrial sequenceを用いた分類学への挑戦2024
- Author(s)
  井上聡; 石川香; 中田和人
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] 老化モデルマウスにおけるミトコンドリア呼吸機能低下と筋病態2024
- Author(s)
  玉城大敬; 石川香; 中田和人
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] ミトコンドリア病モデルマウスを用いた肝臓の病態変遷に関する研究2024
- Author(s)
  栗山貴成; 宮田大輝; 谷春菜; 石川香; 中田和人
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] ミトコンドリアtRNA遺伝子領域の点突然変異は脳機能障害を誘導する2024
- Author(s)
  宮田大輝; 石川香; 服部聡子; 谷春菜; 栗山貴成; 魏范研; 宮川剛; 中田和人
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] 雌マウスの生殖系列から変異型ミトコンドリアが消失する機構の検証2024
- Author(s)
  伊藤香菜子; 佐々木悠馬; 安原菜々子; 中田和人; 石川香
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] ミトコンドリアゲノム変異と表現型：マウス逆遺伝学による探究2024
- Author(s)
  中田和人
- Organizer
  第24回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] ミトコンドリア機能異常によって誘発された筋委縮における持久性運動の効果2023
- Author(s)
  花田翔、白井隆長、石川香、武政徹、中田和人
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] 「老化ミトコンドリア原因説」のマウス逆遺伝学2023
- Author(s)
  玉城大敬、石川香、中田和人
- Organizer
  第21回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] 加齢に伴うミトコンドリアDNAの遺伝様式の変化2023
- Author(s)
  石川香、安原菜々子、伊藤香菜子、佐々木悠馬、林克彦、中田和人
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] Generation and Pathogenic Analyses of Mice with a Mutation in the tRNALeu(UUR) Gene2023
- Author(s)
  Kaori Ishikawa, Haruna Tani, Fan-Yan Wei, and Kazuto Nakada
- Organizer
  The Cold Spring Harbor Asia conference on Mitochondria and Metabolism in Health and Disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] ミトコンドリアDNAの突然変異ががんの性質に与える影響2023
- Author(s)
  齊藤さくら、中田和人、石川香
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] Nuclear-mitochondrial sequenceの分類学への応用2023
- Author(s)
  井上聡、石川香、中田和人
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] ミトコンドリア病MELASのモデルマウス作出に向けた基礎研究2023
- Author(s)
  永田留理、日比保乃郁、石川香、中田和人
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] tRNALeu(UUR)遺伝子に病原性変異を有する新規ミトコンドリア関連疾患モデルマウスの樹立および分子病理学的解析2023
- Author(s)
  谷春菜、石川香、魏范研、中田和人
- Organizer
  第21回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] Drp1機能不全によるミトコンドリア病病態の多様化2023
- Author(s)
  石川香、堅田俊、本間耀、石原孝也、石原直忠、中田和人
- Organizer
  第21回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] モデルマウスを用いた「老化ミトコンドリア（mtDNA）原因説」の再検証2023
- Author(s)
  玉城大敬、石川香、中田和人
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] マウス逆遺伝学的手法を用いた「老化ミトコンドリア（mtDNA）原因説」の検証2023
- Author(s)
  玉城大敬、石川香、中田和人
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] Diversification of mitochondrial disease pathologies through nuclear-mitochondrial crosstalk2022
- Author(s)
  Kaori Ishikawa, Shun Katada, Yo Honma, Yoshimi Ayami, Takaya Ishihara, Naotada Ishihara, and Kazuto Nakada
- Organizer
  The 45th Annual Meeting of the Molecular Biology Society of Japan
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] 「老化ミトコンドリア原因説」のマウス逆遺伝学2022
- Author(s)
  玉城大敬、石川香、中田和人
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] ミトコンドリアtRNALeu(UUR)遺伝子に病原性変異を有する新規ミトコンドリア関連疾患モデルマウスの樹立および分子病理学的解析2022
- Author(s)
  谷春菜、石川香、魏范研、中田和人
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] ミトコンドリアセントラルドグマの破綻病理：ミトコンドリアゲノム関連疾患のマウス逆遺伝学2022
- Author(s)
  中田和人
- Organizer
  第22回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23801
[Presentation] 変異型ミトコンドリアゲノムの逆遺伝学：多様な病態形成機構の理解に向けて2019
- Author(s)
  中田和人
- Organizer
  第19回日本生殖工学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04678
[Presentation] モデルマウスから探るミトコンドリアセントラルドグマの破綻病理2018
- Author(s)
  中田和人
- Organizer
  第56回日本神経眼科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04678
[Presentation] マウス逆遺伝学から理解するミトコンドリアゲノム変異の多階層病理2018
- Author(s)
  中田和人
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04678
[Presentation] Reverse genetic studies on mammalian mitochondrial DNA with pathogenic mutations.2018
- Author(s)
  Kazuto Nakada
- Organizer
  Asian Society for Mitochondrial and Medicine (ASMRM2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04678
[Presentation] ミトコンドリア・セントラルドグマの破綻病理2017
- Author(s)
  中田和人
- Organizer
  The 7th Basic Science Seminar of Women’s Health Care
- Invited
- Data Source
  KAKENHI-PROJECT-16H04678
[Presentation] ミトコンドリア病を発症したモデルマウスにおけるインドール化合物 Mitochonic acid 5 の有効性に関する基礎研究2017
- Author(s)
  小笠原絵美、石原直忠、阿部高明、中田和人
- Organizer
  日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-16H04678
[Presentation] ミトコンドリア・セントラルドグマの破綻病理2017
- Author(s)
  中田和人
- Organizer
  The 7th Basic Science Seminar of Women’s Health Care
- Invited
- Data Source
  KAKENHI-PROJECT-16K14719
[Presentation] ミトコンドリアセントラルドグマの破綻病理2016
- Author(s)
  中田和人
- Organizer
  第16回日本抗加齢医学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-06-11
- Invited
- Data Source
  KAKENHI-PROJECT-16H04678
[Presentation] 変異型mtDNAによる多階層病理2016
- Author(s)
  中田和人
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-16H04678
[Presentation] 変異型ミトコンドリアゲノムによる多階層病理2016
- Author(s)
  中田和人
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-16K14719
[Presentation] ミトコンドリアセントラルドグマの破綻病理2016
- Author(s)
  中田和人
- Organizer
  第16回日本抗加齢医学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-06-11
- Invited
- Data Source
  KAKENHI-PROJECT-16K14719
[Presentation] ミトコンドリアセントラルドグマの破綻病理～多様な病型形成機構の理解に向けて～2015
- Author(s)
  中田和人
- Organizer
  第119回日本眼科学会総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2015-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-23240058
[Presentation] ミトコンドリアゲノム変異のマウス逆遺伝学～ミトコンドリアダイナミクスと病態発症調節～2015
- Author(s)
  中田和人
- Organizer
  第15回日本ミトコンドリア学会年会
- Place of Presentation
  福井県福井市
- Year and Date
  2015-11-20
- Invited
- Data Source
  KAKENHI-PROJECT-23240058
[Presentation] 突然変異型ミトコンドリアゲノムのマウス逆遺伝学2015
- Author(s)
  中田和人
- Organizer
  日本遺伝学会第87回大会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2015-09-24
- Invited
- Data Source
  KAKENHI-PROJECT-23240058
[Presentation] Model mouse studies: Regulation of threshold effects on pathogenesis of mitochondrial DNA-based disease2014
- Author(s)
  Kazuto Nakada
- Organizer
  Euromit 2014
- Place of Presentation
  Tampere, Finland
- Year and Date
  2014-06-15
- Invited
- Data Source
  KAKENHI-PROJECT-23240058
[Presentation] 突然変異型ミトコンドリアゲノムの病原性制御～ミトコンドリア・ダイナミクスの関与～2014
- Author(s)
  中田和人、石原直忠、林純一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-23240058
[Presentation] ミトコンドリア遺伝子疾患の病態発現機構2014
- Author(s)
  中田和人
- Organizer
  アディポ・サイエンスシンポジウム
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2014-08-23
- Invited
- Data Source
  KAKENHI-PROJECT-23240058
[Presentation] ミトコンドリアセントラルドグマの破綻病理に関する基礎研究2014
- Author(s)
  中田和人
- Organizer
  国立遺伝学研究所研究集会～オルガネラゲノムに支配される生命現象～
- Place of Presentation
  国立遺伝学研究所（静岡県三島市）
- Year and Date
  2014-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-23240058
[Presentation] Reverse genetic studies on mutant mitochondrial genomes in mice2013
- Author(s)
  Kazuto Nakada and Jun-Ichi Hayashi
- Organizer
  The 4th International Symposium on Dynamics of Mitochondria (DynaMito2013)
- Place of Presentation
  Okinawa Zanpamisaki Royal Hotel, Okinawa, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-23240058
[Presentation] ミトコンドリア糖尿病のマウス逆遺伝学2012
- Author(s)
  中田和人、林純一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] 病原性ミトコンドリアゲノム変異のマウス逆遺伝学2012
- Author(s)
  中田和人、林純
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] Reverse genetic studies on mammalian mtDNA mutations2011
- Author(s)
  Nakada, K.
- Organizer
  The Eighth European Meeting on Mitochondrial Pathology
- Place of Presentation
  ザラゴザ、スペイン(招待講演)
- Year and Date
  2011-06-22
- Data Source
  KAKENHI-PROJECT-23240058
[Presentation] Reverse genetic studies on defects of mitochondrial central dogma2011
- Author(s)
  Nakada K
- Organizer
  UCL-JSPS International Symposium
- Place of Presentation
  UK
- Year and Date
  2011-02-10
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] Reverse geneticstudies on mammalian mtDNA mutations2011
- Author(s)
  Nakada K, Hayashi J
- Organizer
  European Meeting on Mitochondrial Pathology (Euromit 8)
- Place of Presentation
  Spain
- Year and Date
  2011-06-21
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] Reverse genetic studies on mammalian mtDNA mutations2011
- Author(s)
  Nakada, K.
- Organizer
  The Eighth European Meeting on Mitochondrial Pathology
- Place of Presentation
  ザラゴザ、スペイン(招待講演)
- Year and Date
  2011-06-22
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] Reverse genetic studies on defects of mitochondrial central dogma2011
- Author(s)
  Kazuto Nakada
- Organizer
  UCL-JSPS International Symposium
- Place of Presentation
  London UK
- Year and Date
  2011-02-10
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] モデルマウスから得られた新知見2010
- Author(s)
  中田和人
- Organizer
  第113回日本小児学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] ミトコンドリアセントラルドグマの破綻病理2010
- Author(s)
  中田和人、小笠原絵美、北潔、林純一
- Organizer
  BMB2010, ワークショップ「ミトコンドリア研究の最前線:基礎生命科学から臨床まで」
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] Mouse models of mtDNA defects2010
- Author(s)
  Nakada K, Hayashi J
- Organizer
  Mitochondrial Medicine 2010
- Place of Presentation
  Tokyo
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] Mouse models of mitochondrial defecis2010
- Author(s)
  Kazuto Nakada
- Organizer
  Mitochondrial Medicine 2010
- Place of Presentation
  Arizana, USA
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] ミトコンドリアセントラルドグマの破綻と代謝適応2010
- Author(s)
  中田和人
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] ミトコンドリア遺伝子疾患における乳酸産生とその病原性2009
- Author(s)
  中田和人、小笠原絵美、林純一
- Organizer
  第32回日本分子生物学会大会ワークショップ「代謝適応と破綻に見る新たなミトコンドリア機能研究」
- Place of Presentation
  神戸
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] Mitochondria-related male intertility:Mitochondrial respiration activity is essential for mammalian spermatogenesis2007
- Author(s)
  Nakada, K・Sato, A・Hayashi, JI
- Organizer
  1st European Congress on the Aging male
- Place of Presentation
  Warsaw,Poland
- Data Source
  KAKENHI-PROJECT-17689023
[Presentation] ミトコンドリア糖尿病のマウス逆遺伝学
- Author(s)
  中田和人
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23240058
[Presentation] ミトコンドリア糖尿病のマウス逆遺伝学
- Author(s)
  中田和人
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Invited
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] 病原性ミトコンドリアゲノム変異のマウス逆遺伝学
- Author(s)
  中田和人
- Organizer
  第55回日本腎臓学会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22650091
[Presentation] 病原性ミトコンドリアゲノム変異のマウス逆遺伝学
- Author(s)
  中田和人
- Organizer
  第55回日本腎臓学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23240058

1. 林純一 (60142113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KANNO Shinichirou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. KOSHIBA Takumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 設楽浩志

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. 米川博通

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 小野富男

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 曽田学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 魏范研

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 石原孝也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 石川香

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 多屋長治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 石井里絵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 山本雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 安川武宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakada Kazuto 中田 和人

NAKADA Kazuto 中田 和人

中田 和人 ナカダ カズト

Research Projects

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Studies on replication-related bases in mouse mitochondrial DNAPrincipal Investigator

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Reverse genetic studies on mitochondrial DNA mutations in micePrincipal Investigator

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Reverse genetic studies on mitochondrial DNA with pathogenic mutations in micePrincipal Investigator

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Studies on skeletal muscle fiber-type specific responses to pathogenic mtDNAPrincipal Investigator

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Studies on pathogeneses of mitochondrial DNA-based disordersPrincipal Investigator

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Studies on tissue-specific dynamics of pathogenic mutant mitochondrial DNA in micePrincipal Investigator

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モデルマウスを用いたミトコンドリア病の出生前治療法の開発Principal Investigator

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ミトコンドリアDNA突然変異導入マウスを用いたミトコンドリアゲノムの基礎遺伝学

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突然変異mtDNAを用いたミトコンドリア間機能的相互作用の証明Principal Investigator

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[Book] 細胞生物学2012

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[Journal Article] Endurance swimming exacerbates mitochondrial myopathy in mice with high mtDNA deletions2025

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[Journal Article] Accumulation of mitochondrial DNA with a point mutation in tRNALeu(UUR) gene induces brain dysfunction in mice.2024

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[Journal Article] Pearson syndrome-like anemia induced by accumulation of mutant mtDNA and anemia with imbalanced white blood cell lineages induced by Drp1 deletion in a murine model2022

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Nakada Kazuto 中田和人

NAKADA Kazuto 中田和人

中田和人ナカダカズト