HASHIMOTO Mitsuru 橋本満

… Alternative Names

橋本満ハシモトミツル

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Researcher Number	80359968
External Links
Affiliation (Current)	2025: 松山大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2005: 熊本大学, 大学院医学薬学研究部, 助手 2004 – 2005: 熊本大学, 大学院・医学薬学研究部, 助手
Review Section/Research Field	Principal Investigator Drug development chemistry Except Principal Investigator Drug development chemistry
Keywords	Principal Investigator ミトコンドリア / ATP透過担体 / ADP / ヘキソキナーゼ Except Principal Investigator acyltranslation / molecular design / prodrug / substrate specificity / intestinal absorption / drug disposition … More / hydrolysis / carboxylesterase / 部位特異的変異体 / キメラ酵素 / アシル基転移 / 分子設計 / プロドラッグ / 基質認識性 / 消化管吸収 / 薬物動態 / 加水分解 / カルボキシルエステラーゼ Less

脳特異的なエネルギー代謝を担うヘキソキナーゼの機能制御機構解析と痴呆治療への応用Principal Investigator
- Principal Investigator
  
  橋本満
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kumamoto University
Structural analysis of substrate binding region in carboxylesterase and design of ester-containing drug
- Principal Investigator
  
  IMAI Teruko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kumamoto University

All 2006 2005 Other

All Journal Article

[Journal Article] Identification of esterase expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption2006
- Author(s)
  T.Imai, M.Imoto, H.Sakamoto, M.Hashimoto
- Journal Title
  
  Drug Metabolism and Disposition 33・8
  
  Pages: 1185-1190
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590085
[Journal Article] Roles of Adjoining Asp and Cys Residues of First Matrix-Facing Loop in Transport Activity of Yeast and Bovine Mitochondrial ADP/ATP Carriers2006
- Author(s)
  Y.Kihira, M.Hashimoto, Y.Shinohara, E.Majima, H.Terada
- Journal Title
  
  Journal of Biochemistry (印刷中)
- NAID
  10018847094
- Data Source
  KAKENHI-PROJECT-16790085
[Journal Article] Involvement of carboxylesterase in hydolysis of drug during permeation across rat skin2005
- Author(s)
  Y.Takase, T.Tanaka, M.Hashimoto, T.Imai
- Journal Title
  
  Drug Metabolism Reviews 37
  
  Pages: 389-389
- Data Source
  KAKENHI-PROJECT-16790085
[Journal Article] Identification of esterases expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption2005
- Author(s)
  T.Imai, M.Imoto, H.Sakamoto, M.Hashimoto
- Journal Title
  
  Drug Metabolism and Diposition 33
  
  Pages: 1185-1190
- Data Source
  KAKENHI-PROJECT-16790085
[Journal Article] Identification of esterase expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption2005
- Author(s)
  T.Imai, M.Imoto, H.Sakamoto, M.Hashimoto
- Journal Title
  
  Drug Metabolism and Disposition 33(8)
  
  Pages: 1185-1190
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590085
[Journal Article] The role of carboxyleserase in the rat intestinal absorption of drug and the effect of aging on intestinal esterase activity2005
- Author(s)
  K.Masaki, M.Hashimoto, T.Imai
- Journal Title
  
  Drug Metabolism Reviews 37
  
  Pages: 386-386
- Data Source
  KAKENHI-PROJECT-16790085
[Journal Article] Identification of esterase expressed in Caco-2 Cells and effects of their hydrolyzing activity in predicting human intestinal absorption2005
- Author(s)
  T.Imai, M.Imoto, H.Sakamoto, M.Hashimoto
- Journal Title
  
  Drug Metabolism and Disposition 33・8
  
  Pages: 1185-1190
- Data Source
  KAKENHI-PROJECT-16590085
[Journal Article] Identification of esterase expressed in Caco-2 cells and an effect of its hydrolyzing activity on prediction of human intestinal absorption
- Author(s)
  今井輝子, 井本真澄, 坂本久恵, 橋本満
- Journal Title
  
  Drug Metabolism and Disposition (印刷中)
- Data Source
  KAKENHI-PROJECT-16790085

1. IMAI Teruko (70176478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

HASHIMOTO Mitsuru 橋本 満

橋本 満 ハシモト ミツル

Research Projects

Research Products

Co-Researchers

脳特異的なエネルギー代謝を担うヘキソキナーゼの機能制御機構解析と痴呆治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural analysis of substrate binding region in carboxylesterase and design of ester-containing drug

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Identification of esterase expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Roles of Adjoining Asp and Cys Residues of First Matrix-Facing Loop in Transport Activity of Yeast and Bovine Mitochondrial ADP/ATP Carriers2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Involvement of carboxylesterase in hydolysis of drug during permeation across rat skin2005

Author(s)

Journal Title

Data Source

[Journal Article] Identification of esterases expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption2005

Author(s)

Journal Title

Data Source

[Journal Article] Identification of esterase expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] The role of carboxyleserase in the rat intestinal absorption of drug and the effect of aging on intestinal esterase activity2005

Author(s)

Journal Title

Data Source

[Journal Article] Identification of esterase expressed in Caco-2 Cells and effects of their hydrolyzing activity in predicting human intestinal absorption2005

Author(s)

Journal Title

Data Source

[Journal Article] Identification of esterase expressed in Caco-2 cells and an effect of its hydrolyzing activity on prediction of human intestinal absorption

Author(s)

Journal Title

Data Source

HASHIMOTO Mitsuru 橋本満

橋本満ハシモトミツル