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HIJIKATA ATSUSHI  土方 敦司

… Alternative Names

HIJIKATA Atsushi  土方 敦司

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Researcher Number 80415273
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-4297-8368
Affiliation (Current) 2025: 東京薬科大学, 生命科学部, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 東京薬科大学, 生命科学部, 准教授
2015 – 2021: 長浜バイオ大学, バイオサイエンス学部, プロジェクト特任講師
2013: 長浜バイオ大学, 公私立大学の部局等, 講師
2011 – 2013: 独立行政法人理化学研究所, 免疫ゲノミクス研究グループ, リサーチアソシエイト
Review Section/Research Field
Principal Investigator
Basic Section 62010:Life, health and medical informatics-related / Medical genome science
Except Principal Investigator
Basic Section 62010:Life, health and medical informatics-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Transformative Research Areas, Section (III) / Life / Health / Medical informatics / Pediatrics
Keywords
Principal Investigator
タンパク質立体構造 / レアバリアント / 構造バイオインフォマティクス / ミスセンス変異 / バイオインフォマティクス / 立体構造 / 結合親和性 / タンパク質複合体 / エピトープバリアント / 抗原 … More / 抗体医薬品 / 遺伝子性疾患 / 遺伝子疾患 / 構造環境 / 疾患関連変異 / 分子機能 / 疾患関連ゲノム変異 / タンパク質局所構造 / 局所構造 / アミノ酸残基 / ゲノムバリアント / 疾患変異解析 / ヒト遺伝子疾患 / 機能獲得 / 優性阻害 / 超分子複合体 / 機能獲得変異 / ドミナントネガティブ / ハプロ不全 / データベース / 遺伝性疾患 … More
Except Principal Investigator
機械学習 / 相互作用ダイナミクス / 薬剤応答 / 近位依存性ビオチン標識 / インタラクトーム / EGFR / 祖先型遺伝子 / 分子進化 / 光合成 / 生命分子計算 / アロステリックサイト / クリプティックサイト / 疾患関連変異 / アロステリック制御 / クリプトサイト / タンパク質機能推定 / タンパク質構造 / 疾患関連変異分布 / 低分子結合予測 / ピリドキサールリン酸 / 出芽酵母 / 酵素 / 機能予測 / データベース / SNV / 低分子化合物 / 機能部位予測 / 機能未知タンパク質 / 選択的スプライシング / ナイーブT細胞 / 骨髄異形成症候群 / GATA2 / NK細胞分化 / B細胞分化 / 樹状細胞分化 / 原発性免疫不全症 Less
  • Research Projects

    (9 results)
  • Research Products

    (66 results)
  • Co-Researchers

    (25 People)
  •  Analysis of the protein-protein interaction dynamics of EGFR on the plasma membrane using proximity biotinylation enzyme

    • Principal Investigator
      澤崎 達也
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Ehime University
  •  Decoding the environmental adaptation strategies of photo-synthesis system via restoration of ancient proteins

    • Principal Investigator
      白井 剛
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Nagahama Institute of Bio-Science and Technology
  •  抗体医薬標的におけるミスセンスレアバリアントの結合親和性変化を評価する手法の確立Principal Investigator

    • Principal Investigator
      土方 敦司
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 62010:Life, health and medical informatics-related
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  疾患関連変異のタンパク質構造上の三次元分布を基点とした未知の機能部位探索法の確立

    • Principal Investigator
      今井 賢一郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 62010:Life, health and medical informatics-related
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Development of a prediction method for cofactors binding to uncharacterized enzymes using feedback from experimental validations

    • Principal Investigator
      Shionyu Masafumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 62010:Life, health and medical informatics-related
    • Research Institution
      Nagahama Institute of Bio-Science and Technology
  •  Developing a method for evaluating variants of uncertain significance in humans based on protein structuresPrincipal Investigator

    • Principal Investigator
      Hijikata Atsushi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 62010:Life, health and medical informatics-related
    • Research Institution
      Nagahama Institute of Bio-Science and Technology
  •  Development of a method for predicting functional sites in function-unknown splicing isoforms

    • Principal Investigator
      Shionyu Masafumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Life / Health / Medical informatics
    • Research Institution
      Nagahama Institute of Bio-Science and Technology
  •  Development of a new method to predict disease-causing mechanisms of missense mutationsPrincipal Investigator

    • Principal Investigator
      HIJIKATA Atsushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical genome science
    • Research Institution
      Nagahama Institute of Bio-Science and Technology
  •  Analysis of pathophysiology and identification of the causative gene(s) of primary immunodeficiency with B, NK, dendritic cell deficiency

    • Principal Investigator
      IMAI KOHSUKE
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tokyo Medical and Dental University

All 2023 2021 2020 2019 2018 2017 2016 2015 2012 2011

All Journal Article Presentation

  • [Journal Article] Involvement of mTOR pathway in neurodegeneration in NSF-related developmental and epileptic encephalopathy2023

    • Author(s)
      Hayashi Takahiro、Yano Naoko、Kora Kengo、Yokoyama Atsushi、Maizuru Kanako、Kayaki Taisei、Nishikawa Kinuko、Osawa Mitsujiro、Niwa Akira、Takenouchi Toshiki、Hijikata Atsushi、Shirai Tsuyoshi、Suzuki Hisato、Kosaki Kenjiro、Saito Megumu K、Takita Junko、Yoshida Takeshi
    • Journal Title

      Human Molecular Genetics

      Volume: 32 Issue: 10 Pages: 1683-1697

    • DOI

      10.1093/hmg/ddad008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K12250, KAKENHI-PROJECT-21K15863, KAKENHI-PROJECT-20H03642, KAKENHI-PROJECT-23K21721
  • [Journal Article] A novel variant of NR5A1, p.R350W implicates potential interactions with unknown co-factors or ligands2023

    • Author(s)
      Gau Maki、Suga Ryota、Hijikata Atsushi、Kashimada Ayako、Takagi Masatoshi、Nakagawa Ryuichi、Takasawa Kei、Shirai Tsuyoshi、Kashimada Kenichi、Morio Tomohiro
    • Journal Title

      Frontiers in Endocrinology

      Volume: 13 Pages: 1033074-1033074

    • DOI

      10.3389/fendo.2022.1033074

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K12250, KAKENHI-PROJECT-23K21721
  • [Journal Article] Current status of structure-based drug repurposing against COVID-19 by targeting SARS-CoV-2 proteins2021

    • Author(s)
      Hijikata Atsushi、Shionyu Clara、Nakae Setsu、Shionyu Masafumi、Ota Motonori、Kanaya Shigehiko、Shirai Tsuyoshi
    • Journal Title

      Biophysics and Physicobiology

      Volume: 18 Issue: 0 Pages: 226-240

    • DOI

      10.2142/biophysico.bppb-v18.025

    • NAID

      130008106407

    • ISSN
      2189-4779
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K12211, KAKENHI-PROJECT-18H03331, KAKENHI-PLANNED-20H05932, KAKENHI-PROJECT-23K21721
  • [Journal Article] Evaluating cepharanthine analogues as natural drugs against SARS‐CoV‐22021

    • Author(s)
      Hijikata Atsushi、Shionyu‐Mitsuyama Clara、Nakae Setsu、Shionyu Masafumi、Ota Motonori、Kanaya Shigehiko、Hirokawa Takatsugu、Nakajima Shogo、Watashi Koichi、Shirai Tsuyoshi
    • Journal Title

      FEBS Open Bio

      Volume: 12 Issue: 1 Pages: 285-294

    • DOI

      10.1002/2211-5463.13337

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K12211, KAKENHI-PROJECT-18H03331, KAKENHI-PROJECT-21K15458, KAKENHI-PLANNED-20H05932, KAKENHI-PROJECT-23K21721
  • [Journal Article] Detailed analysis of Japanese patients with adenosine deaminase 2 deficiency reveals characteristic elevation of type II interferon signature and STAT1 hyperactivation.2021

    • Author(s)
      Nihira H, Izawa K, Ito M, Umebayashi H, Okano T, Kajikawa S, ...Yasumi T.
    • Journal Title

      J Allergy Clin Immunol

      Volume: 印刷中 Issue: 2 Pages: 00157-3

    • DOI

      10.1016/j.jaci.2021.01.018

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16355, KAKENHI-PROJECT-19H03613, KAKENHI-PROJECT-18K18154, KAKENHI-PROJECT-19K08299, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-21K19405
  • [Journal Article] WDR11 is another causative gene for coloboma, cardiac anomaly and growth retardation in 10q26 deletion syndrome2019

    • Author(s)
      Sutani Akito、Shima Hirohito、Hijikata Atsushi、Hosokawa Susumu、Katoh-Fukui Yuko、Takasawa Kei、Suzuki Erina、Doi Shozaburo、Shirai Tsuyoshi、Morio Tomohiro、Fukami Maki、Kashimada Kenichi
    • Journal Title

      European Journal of Medical Genetics

      Volume: 印刷中 Issue: 1 Pages: 103626-103626

    • DOI

      10.1016/j.ejmg.2019.01.016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06926, KAKENHI-PROJECT-18K18154, KAKENHI-PLANNED-17H06428
  • [Journal Article] Developing a new method to predict the effect of the missense mutations on the protein function and phenotypes2018

    • Author(s)
      Hijikata Atsushi
    • Journal Title

      Impact

      Volume: 2018 Issue: 12 Pages: 35-37

    • DOI

      10.21820/23987073.2018.12.35

    • Open Access
    • Data Source
      KAKENHI-PROJECT-18K18154
  • [Journal Article] Clinical characteristics of adolescent cases with Type A insulin resistance syndrome caused by heterozygous mutations in the β-subunit of the insulin receptor (INSR) gene2018

    • Author(s)
      Takasawa Kei、Tsuji-Hosokawa Atsumi、Takishima Shigeru、Wada Yasunori、Nagasaki Keisuke、Dateki Sumito、Numakura Chikahiko、Hijikata Atsushi、Shirai Tsuyoshi、Kashimada Kenichi、Morio Tomohiro
    • Journal Title

      Journal of Diabetes

      Volume: 11 Issue: 1 Pages: 46-54

    • DOI

      10.1111/1753-0407.12797

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15660, KAKENHI-PROJECT-18K18154, KAKENHI-PROJECT-17H01818
  • [Journal Article] Molecular mechanisms of insulin resistance in 2 cases of primary insulin receptor defect-associated diseases.2017

    • Author(s)
      Tsuji-Hosokawa, A., Takasawa, K., Nomura, R., Miyakawa, Y., Numakura, C., Hijikata, A., Shirai, T., Ogawa, Y., Kashimada, K. & Morio, T.
    • Journal Title

      Pediatr Diabetes

      Volume: Feb 9 Issue: 8 Pages: 917-924

    • DOI

      10.1111/pedi.12508

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K00411, KAKENHI-PROJECT-15K19602, KAKENHI-PROJECT-15K21487
  • [Journal Article] Decoding disease-causing mechanisms of missense mutations from supramolecular structures2017

    • Author(s)
      Hijikata A, Tsuji T, Shionyu M, Shirai T
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 8541-8541

    • DOI

      10.1038/s41598-017-08902-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01818, KAKENHI-PROJECT-15K00411, KAKENHI-PROJECT-15K21487
  • [Journal Article] The role of the Prod1 membrane anchor in newt limb regeneration2017

    • Author(s)
      Nomura, K., Tanimoto, Y., Hayashi, F., Harada, E., Shan, X.-Y., Shionyu, M., Hijikata, A., Shirai, T., Morigaki, K., Shimamoto, K.
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 56 Issue: 1 Pages: 270-274

    • DOI

      10.1002/anie.201609703

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26291031, KAKENHI-PROJECT-15K00411, KAKENHI-PROJECT-15K14489, KAKENHI-PROJECT-15K21487, KAKENHI-PROJECT-17KT0024, KAKENHI-PROJECT-17H03666
  • [Journal Article] Structural and Functional Analysis of the C-Terminal Region of FliG, an Essential Motor Component of Vibrio Na + -Driven Flagella2017

    • Author(s)
      Miyanoiri Yohei、Hijikata Atsushi、Nishino Yuuki、Gohara Mizuki、Onoue Yasuhiro、Kojima Seiji、Kojima Chojiro、Shirai Tsuyoshi、Kainosho Masatsune、Homma Michio
    • Journal Title

      Structure

      Volume: 25 Issue: 10 Pages: 1540-1548

    • DOI

      10.1016/j.str.2017.08.010

    • NAID

      120006375873

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26291013, KAKENHI-PUBLICLY-17H05836, KAKENHI-PLANNED-26119005, KAKENHI-PROJECT-16J03916, KAKENHI-PROJECT-15K06966, KAKENHI-PROJECT-16K14681, KAKENHI-PROJECT-15K21487, KAKENHI-PUBLICLY-17H05873, KAKENHI-PROJECT-17H03641
  • [Journal Article] Molecular Mechanism and Structural Basis of Gain of Function of STAT1 Caused by Pathogenic R274Q Mutation2017

    • Author(s)
      Fujiki R, Hijikata A, Shirai T, Okada S, Kobayashi M, Ohara O
    • Journal Title

      J Biol Chem.

      Volume: 292 Issue: 15 Pages: 6240-6254

    • DOI

      10.1074/jbc.m116.753848

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05355, KAKENHI-PROJECT-15K00411, KAKENHI-PROJECT-16K15528, KAKENHI-PROJECT-15K21487
  • [Journal Article] Identification of a High-Frequency Somatic NLRC4 Mutation as a Cause of Autoinflammation by Pluripotent Cell-Based Phenotype Dissection.2017

    • Author(s)
      Kawasaki Y, Oda H, Ito J, Niwa A, Tanaka T, Hijikata A, Seki R, Nagahashi A, Osawa M, Asaka I, Watanabe A, Nishimata S, Shirai T, Kawashima H, Ohara O, Nakahata T, Nishikomori R, Heike T, Saito MK.
    • Journal Title

      Arthritis Rheumatol.

      Volume: 69 Issue: 2 Pages: 447-459

    • DOI

      10.1002/art.39960

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26253062, KAKENHI-PROJECT-15H04876, KAKENHI-PROJECT-15K00411, KAKENHI-PROJECT-15K06921, KAKENHI-PROJECT-15K21487
  • [Journal Article] Novel AVPR2 mutation causing partial nephrogenic diabetes insipidus in a Japanese family2016

    • Author(s)
      Yamashita S, Hata A, Usui T, Oda H, Hijikata A, Shirai T, Kaneko N, Hata D
    • Journal Title

      J. Pediatr. Endocrinol. Metab.

      Volume: 5 Issue: 5 Pages: 591-596

    • DOI

      10.1515/jpem-2015-0323

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24370046, KAKENHI-PROJECT-25280109, KAKENHI-PROJECT-15K00411, KAKENHI-PROJECT-15K21487
  • [Journal Article] Classification of ligand molecules in PDB with graph match-based structural superposition.2016

    • Author(s)
      Shionyu-Mitsuyama, C., Hijikata, A., Tsuji, T. & Shirai, T.
    • Journal Title

      J Struct Funct Genomics.

      Volume: 17 Pages: 135-146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Journal Article] Classification of ligand molecules in PDB with graph match-based structural superposition.2016

    • Author(s)
      Shionyu-Mitsuyama, C., Hijikata, A., Tsuji, T. & Shirai, T.
    • Journal Title

      J Struct Funct Genomics.

      Volume: 17 Issue: 4 Pages: 135-146

    • DOI

      10.1007/s10969-016-9209-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Journal Article] Structural and functional analyses of Barth syndrome-causing mutations and alternative splicing in the tafazzin acyltransferase domain.2015

    • Author(s)
      Hijikata A., Yura K., Ohara O., Go M.
    • Journal Title

      Meta Gene

      Volume: 4 Pages: 92-106

    • DOI

      10.1016/j.mgene.2015.04.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K00411, KAKENHI-PROJECT-15K21487
  • [Journal Article] Detection of base substitution-type somatic mosaicism of the NLRP3 gene with > 99.9% statistical confidence by massively parallel sequencing2012

    • Author(s)
      Izawa, K., Hijikata A., Tanaka, N., Kawai, T.,Saito, K.M.,Goldbach-Mansky, R.,Aksentijevich,I., Yasumi, T., Nakahata, T., Heike, T.,Nishikomori, R. & Ohara, O.
    • Journal Title

      DNA Res

      Volume: 19 Pages: 143-152

    • Data Source
      KAKENHI-PROJECT-23591561
  • [Journal Article] Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloiddifferentiation2012

    • Author(s)
      Takagi, S., Saito, Y., Hijikata A., anaka S, Watanabe T, Hasegawa T, Mochizuki S, Kunisawa J, Kiyono H, Koseki H, Ohara O, Saito T, Taniguchi S, Shultz LD, Ishikawa F.
    • Journal Title

      Blood

      Volume: 119 Pages: 2768-2777

    • Data Source
      KAKENHI-PROJECT-23591561
  • [Journal Article] Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.2012

    • Author(s)
      Takagi, S
    • Journal Title

      Blood

      Volume: 119 Issue: 12 Pages: 2768-2777

    • DOI

      10.1182/blood-2011-05-353201

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-23591561, KAKENHI-PROJECT-24229004, KAKENHI-ORGANIZER-24111001
  • [Journal Article] Revisiting gap locations in amino acid sequence alignments and a proposal for a method to improvethem by introducing solvent accessibility2011

    • Author(s)
      Hijikata A., Yura K., Noguti T. & Go M.
    • Journal Title

      Proteins

      Volume: 79 Pages: 1868-77

    • Data Source
      KAKENHI-PROJECT-23591561
  • [Journal Article] Revisiting gap locations in amino acid sequence alignments and a proposal for a method to improve them by introducing solvent accessibility2011

    • Author(s)
      Hijikata, A., Yura, K., Noguti, T. & Go, M.
    • Journal Title

      Proteins

      Volume: 79 Issue: 6 Pages: 1868-77

    • DOI

      10.1002/prot.23011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591561
  • [Journal Article] The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4(+) T cells2011

    • Author(s)
      Motomura Y., Kitamura H., Hijikata A.,Matsunaga, Y., Matsumoto, K., Inoue, H.,Atarashi, K., Hori, S., Watarai, H., Zhu, J.,Taniguchi, M. & Kubo, M.
    • Journal Title

      Nat Immunol

      Volume: 12 Pages: 450-9

    • Data Source
      KAKENHI-PROJECT-23591561
  • [Journal Article] The RIKEN integrated database of mammals2011

    • Author(s)
      Masuya H, Makita Y, Kobayashi N, Nishikata K, Yoshida Y, Mochizuki Y, Doi K, Takatsuki T, Waki K, Tanaka N, Ishii M, Matsushima A, Takahashi S, Hijikata A, Kozaki K, Furuichi T, Kawaji H, Wakana S, Nakamura Y, Yoshiki A, Murata T, Fukami-Kobayashi K, Mohan S, Ohara O, Hayashizaki Y, Mizoguchi R, Obata Y, Toyoda T.
    • Journal Title

      Nucleic Acids Res

    • Data Source
      KAKENHI-PROJECT-23591561
  • [Journal Article] Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo2011

    • Author(s)
      Takagi, H., Fukaya, T., Eizumi, K., Sato, Y.,Sato, K., Shibazaki, A., Otsuka, H., Hijikata A.,Watanabe, T., Ohara, O., Kaisho, T. & Malissen, B.
    • Journal Title

      Immunity

      Volume: 35 Pages: 958-71

    • Data Source
      KAKENHI-PROJECT-23591561
  • [Presentation] Searchfor novel protein functional sites based on the spatial distribution of disease-associated missense variants2023

    • Author(s)
      本野千恵、土方 敦司、広川貴次、今井賢一郎
    • Organizer
      第51回構造活性相関シンポジウム
    • Data Source
      KAKENHI-PROJECT-21H03551
  • [Presentation] A search method for novel protein functional site based on the spatial distribution of disease-associated missense variants2023

    • Author(s)
      本野千恵、土方 敦司、広川貴次、今井賢一郎
    • Organizer
      CBI学会2023年大会
    • Data Source
      KAKENHI-PROJECT-21H03551
  • [Presentation] A search method for novel protein functional site based on the spatial distribution of disease-associated missense variants2023

    • Author(s)
      本野千恵、土方 敦司、広川貴次、今井賢一郎
    • Organizer
      8th Autumn School of Chemoinformatics in Nara
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03551
  • [Presentation] タンパク質複合体構造情報に基づく抗体医薬品標的ヒトタンパク質におけるゲノムバリアントの網羅的解析2023

    • Author(s)
      小野幹太、土方敦司
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K12250
  • [Presentation] 光合成ユビキティー:植物はどうして様々な環境で光合成できるようになったのか?2023

    • Author(s)
      土方 敦司, 白井 剛, 坂本 亘, 皆川 純, 吉田 啓亮, 日原 由香子, 斉藤 圭亮, 栗栖 源嗣
    • Organizer
      日本科学振興協会(JAAS)年次総会2023 「会いに行ける科学者フェス」
    • Invited
    • Data Source
      KAKENHI-PLANNED-23H04964
  • [Presentation] Protein-cofactor binding prediction with graph neural networks2021

    • Author(s)
      Masafumi Shionyu, Atsushi Hijikata
    • Organizer
      第59回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-19K12211
  • [Presentation] グラフニューラルネットワークを用いたタンパク質の低分子リガンド結合予測2021

    • Author(s)
      塩生真史, 土方敦司
    • Organizer
      第21回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-19K12211
  • [Presentation] Prediction of PLP-binding proteins by using machine learning-based methods2020

    • Author(s)
      Masafumi Shionyu, Tomohiro Hatta, Atsushi Hijikata
    • Organizer
      第58回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-19K12211
  • [Presentation] 結合傾向値を特徴量とした機械学習による低分子リガンド結合残基予測2019

    • Author(s)
      塩生真史, 山崎まど香, 土方敦司
    • Organizer
      第19回日本蛋白質科学会年会 第71回日本細胞生物学会大会 合同年次大会
    • Data Source
      KAKENHI-PROJECT-19K12211
  • [Presentation] A local structural environment descriptor towards evaluating impact of rare variants in humans on protein structures and functions2019

    • Author(s)
      Atsushi Hijikata, Masafumi Shionyu, Tsuyoshi Shirai
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-18K18154
  • [Presentation] タンパク質高次構造に基づくヒトミスセンスバリアントの分子機能への影響を予測する手法の開発2019

    • Author(s)
      土方 敦司、塩生 真史、白井 剛
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K18154
  • [Presentation] Machine learning models for predicting ligand-binding sites using residue-wise features2019

    • Author(s)
      Masafumi Shionyu, Atsushi Hijikata
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-19K12211
  • [Presentation] タンパク質高次構造情報に基づくヒトミスセンス変異の分子機能への影響を予測する手法の開発2019

    • Author(s)
      土方 敦司、塩生 真史、白井 剛
    • Organizer
      第19回日本蛋白質科学会年会 第71回日本細胞生物学会大会 合同年次大会
    • Data Source
      KAKENHI-PROJECT-18K18154
  • [Presentation] A local structural environment descriptor towards evaluating impact of rare variants in humans on protein structures and functions.2019

    • Author(s)
      Atsushi Hijikata, Masafumi Shionyu, Tsuyoshi Shirai
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-19K12211
  • [Presentation] たんぱく質の高次構造から読み解くゲノム変異と疾患表現型との関係2019

    • Author(s)
      土方敦司
    • Organizer
      第17回ゲノム・オミックス連携推進セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K18154
  • [Presentation] Development of a method for predicting pathogenicity of missense variants incorporating supramolecular structural information2018

    • Author(s)
      土方敦司、塩生真史、白井剛
    • Organizer
      第56回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-18K18154
  • [Presentation] Towards predicting functional consequences of genetic variants in humans through supramolecular complex structures2017

    • Author(s)
      土方敦司、辻敏之、塩生真史、白井剛
    • Organizer
      第55回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] タンパク質超分子複合体構造から読み解くミスセンス変異と疾患表現型との関係2017

    • Author(s)
      土方敦司、辻敏之、塩生真史、白井剛
    • Organizer
      第5回NGS現場の会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] 分子動力学とNMRで迫るべん毛モーターの回転方向制御機構2017

    • Author(s)
      土方敦司
    • Organizer
      平成29年度日本分光学会NMR分光部会講習会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] Mutation@A Glance: ヒトにおける意義不明バリアントの解明を目指した統合解析ツール2017

    • Author(s)
      土方敦司、白井剛
    • Organizer
      2017年度生命科学系合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] 超分子複合体から読み解くミスセンス変異と疾患表現型の関係2017

    • Author(s)
      土方敦司、辻敏之、塩生真史、白井剛
    • Organizer
      第17回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] Mutation@A Glance: ヒト遺伝子バリアント統合可視化ツール2017

    • Author(s)
      土方敦司、白井剛
    • Organizer
      トーゴーの日2017
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] 超分子複合体から読み解くミスセンス変異と疾患表現型の関係2017

    • Author(s)
      土方敦司、辻敏之、塩生真史、白井剛
    • Organizer
      第17回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] Mutation@A Glance: ヒトにおける意義不明バリアントの解明を目指した統合解析ツール2017

    • Author(s)
      土方敦司、白井剛
    • Organizer
      2017年度生命科学系合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] Decoding disease-causing mechanisms of missense mutations from supramolecular structures2017

    • Author(s)
      土方敦司、辻敏之、塩生真史、白井剛
    • Organizer
      第6回生命医薬情報連合大会(IIBMP2017)
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] Decoding disease-causing mechanisms of missense mutations from supramolecular structures2017

    • Author(s)
      土方敦司、辻敏之、塩生真史、白井剛
    • Organizer
      第6回生命医薬情報連合大会(IIBMP2017)
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] Towards predicting functional consequences of genetic variants in humans through supramolecular complex structures2017

    • Author(s)
      土方敦司、辻敏之、塩生真史、白井剛
    • Organizer
      第55回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] Mutation@A Glance: ヒト遺伝子バリアント統合可視化ツール2017

    • Author(s)
      土方敦司、白井剛
    • Organizer
      トーゴーの日シンポジウム2017
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] Structural and functional analysis of the C-terminal region of FliG, an essential motor component of Vibrio Na+-driven flagellar by NMR spectroscopy and molecular dynamics simulation2017

    • Author(s)
      土方敦司、宮ノ入洋平、西野優紀、郷原瑞樹、尾上靖宏、小嶋誠司、児嶋長次郎、白井剛、甲斐荘正恒、本間道夫
    • Organizer
      公開シンポジウム「運動超分子マシナリーが織りなす調和と多様性」
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] タンパク質超分子複合体構造から読み解くミスセンス変異と疾患表現型との関係2017

    • Author(s)
      土方敦司、辻敏之、塩生真史、白井剛
    • Organizer
      第5回NGS現場の会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] A new approach for protein-ligand binding predictions based on matching of vector-presented amino acid residues2016

    • Author(s)
      Hijikata A, Shionyu M, Shirai T
    • Organizer
      第5回生命医薬情報学連合大会
    • Place of Presentation
      東京国際交流館プラザ平成(東京都江東区)
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] タンパク質の高次構造から読み解く遺伝性疾患多様性メカニズム2016

    • Author(s)
      土方敦司, 辻 敏之, 塩生真史, 白井 剛
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] タンパク質の高次構造から読み解く遺伝性疾患多様性メカニズム2016

    • Author(s)
      土方 敦司, 辻 敏之, 塩生 真史, 白井 剛
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜国際平和会議場(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] アミノ酸残基相互作用ベクトルマッチに基づくタンパク質―低分子ドッキング法2016

    • Author(s)
      土方敦司、塩生真史、白井 剛
    • Organizer
      第16回日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] A new approach for protein-ligand binding predictions based on matching of vector-represented amino acid residues2016

    • Author(s)
      Atsushi Hijikata, Masafumi Shionyu, Tsuyoshi Shirai
    • Organizer
      第5回生命医薬情報学連合大会
    • Place of Presentation
      東京国際交流館プラザ平成(東京都江東区)
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] ベクトル表現化したアミノ酸残基のマッチングによるタンパク質-リガンド結合予測2016

    • Author(s)
      Atsushi Hijikata, Masafumi Shionyu, Tsuyoshi Shirai
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] アミノ酸残基相互作用ベクトルマッチに基づくタンパク質―低分子ドッキング法2016

    • Author(s)
      土方敦司, 塩生真史, 白井 剛
    • Organizer
      第16回日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場(福岡市博多区)
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] ベクトル表現化したアミノ酸残基のマッチングによるタンパク質―リガンド結合予測2016

    • Author(s)
      土方敦司、塩生真史、白井 剛
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Data Source
      KAKENHI-PROJECT-15K21487
  • [Presentation] TafazzinトランスアシラーゼドメインにおけるBarth症候群関連変異と選択的スプライシングの構造および機能に関する影響2015

    • Author(s)
      土方敦司、由良敬、小原收、郷通子
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-04
    • Data Source
      KAKENHI-PROJECT-15K00411
  • [Presentation] TafazzinトランスアシラーゼドメインにおけるBarth症候群関連変異と選択的スプライシングの構造および機能に関する影響2015

    • Author(s)
      土方敦司、由良敬、小原收、郷通子
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-15K21487
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  • 2.  IMAI KOHSUKE (90332626)
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  • 13.  NAKATA Keisuke
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  • 19.  森垣 憲一
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  • 20.  林 文夫
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