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Isoo Naoyuki  磯尾 直之

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… Alternative Names

ISOO Naoyuki  磯尾 直之

ISOーO Naoyuki  磯尾 直之

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Researcher Number 80420214
Affiliation (Current) 2025: 帝京大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2025: 帝京大学, 医学部, 准教授
2023: 帝京大学, 医学部, 准教授
2017 – 2022: 帝京大学, 医学部, 講師
2014 – 2016: 東京大学, 医科学研究所, 助教
2007 – 2011: The University of Tokyo, The institute of Medical Science, Assist
2006: 東京大学, 大学院医学系研究科, 助手
Review Section/Research Field
Principal Investigator
Infectious disease medicine / Basic Section 54030:Infectious disease medicine-related
Except Principal Investigator
Basic Section 52020:Neurology-related / Metabolomics / Cardiovascular medicine / Pediatrics
Keywords
Principal Investigator
エクソソーム / マラリア / CD36 / 血小板 / HDL / エンドサイトーシス / CD41 / スカベンジャー受容体 / リポ蛋白
Except Principal Investigator
脳内伝播 … More / タウ / エクソソーム / アルツハイマー病 / ステロリン / 輸送機構 / 心臓超音波検査 / バイオマーカー / 左室拡張機能 / 心エコー図検査 / 薬剤性心筋症 / atherosclerosis / sterolin / cytokine / inflammation / plant sterol / macrophage / 動脈硬化 / サイトカイン / 炎症 / 植物ステロール / マクロファージ / 循環器・高血圧 / バーシカン / 分化 / 発生 / 心血管 / 先天異常学・奇形学 / 発生学・形態形成学 / spheroid HepG2細胞 / APoE rich Lipoprotein / 胆汁 / 肝臓 / NPC1L1 / ABCG8 / ABCG5 Less
  • Research Projects

    (9 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (16 People)
  •  病原性タウの脳内伝播を担うエクソソームの輸送先決定機構の解明と治療応用

    • Principal Investigator
      磯尾 紀子
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Teikyo University
  •  脂質受容体をマラリア原虫に供給するエクソソームのトロピズムの解明と治療への応用Principal Investigator

    • Principal Investigator
      磯尾 直之
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54030:Infectious disease medicine-related
    • Research Institution
      Teikyo University
  •  エクソソームの輸送先選択性に基づきタウの伝播阻止を目指すアルツハイマー病治療

    • Principal Investigator
      磯尾 紀子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Teikyo University
  •  Study on the host-parasite communications in malaria mediated by platelet-derived exosomes.Principal Investigator

    • Principal Investigator
      Iso-o Naoyuki
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Teikyo University
  •  Host Sterol Supply to Plasmodium Parasites as the Therapeutic Target in MalariaPrincipal Investigator

    • Principal Investigator
      ISO-O Naoyuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      The University of Tokyo
  •  Prediction of drug-induced cardiomyopathy with transthoracic echocardiography and cardiac biomarkers

    • Principal Investigator
      Watanabe Atai
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      The University of Tokyo
  •  The role of Cspg-2 gene in embryonic cardiovascular development

    • Principal Investigator
      NAKAOKA Takashi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tokyo Women's Medical University
      The University of Tokyo
  •  Analyses on the mechanisms for cholesterol excretion from liver.

    • Principal Investigator
      TSUKAMOTO Kazuhisa
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Role of Plant Sterol and Sterolin in Macrophages and T Lynphocytes

    • Principal Investigator
      TSUKAMOTO Kazuhisa
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo

All 2023 2021 2020 2018 2016 2011 2009

All Journal Article Presentation

  • [Journal Article] Malaria Parasites Hijack Host Receptors From Exosomes to Capture Lipoproteins2021

    • Author(s)
      Iso-o N, Komatsuya K, Tokumasu F, Isoo N, Ishigaki T, Yasui H, Yotsuyanagi H, Hara M and Kita K
    • Journal Title

      Front. Cell Dev. Biol.

      Volume: 9 Pages: 749153-749153

    • DOI

      10.3389/fcell.2021.749153

    • NAID

      120007188606

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10014
  • [Journal Article] Plant Sterols Increased IL-6 and TNF-α Secretion from Macrophages, but to a Lesser Extent than Cholesterol.2011

    • Author(s)
      Kurano M, Iso-O N, Hara M, Noiri E, Koike K, Kadowaki T, Tsukamoto K.
    • Journal Title

      J Atheroscler Thromb (Epub ahead of print)

    • NAID

      130004845378

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591079
  • [Journal Article] Identification of a novel mutation for phytosterolemia. Genetic analyses of 2 cases.2009

    • Author(s)
      Togo M, Hashimoto Y, Iso-O N, Kurano M, Hara M, Kadowaki T, Koike K, Tsukamoto K.
    • Journal Title

      Clin Chim Acta. 401(1-2)(Epub 2008 Nov 5)

      Pages: 165-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591079
  • [Presentation] Characterization of tau-containing exosomes derived from Neuro2a cells2023

    • Author(s)
      Noriko Isoo
    • Organizer
      Society for Neuroscience 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07503
  • [Presentation] Malaria Parasites Hijack Host Scavenger Receptors for Lipoprotein Uptake Using Platelet-derived Exosomes2021

    • Author(s)
      Naoyuki Iso-o, Keisuke Komatsuya, Fuyuki Tokumasu, Noriko Isoo, Tomohiro Ishigaki, Hiroshi Yasui, Hiroshi Yotsuyanagi, Masumi Hara, Kiyoshi Kita
    • Organizer
      The 19th International Symposium on Atherosclerosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10014
  • [Presentation] 赤内型マラリア原虫は宿主血小板由来エクソソームを介して脂質受容体CD36を供給され、増殖に必要なステロールを宿主HDLから取り込む2020

    • Author(s)
      磯尾直之、小松谷啓介、徳舛富由樹、原眞純、四柳宏、北潔
    • Organizer
      第89回日本寄生虫学会大会
    • Data Source
      KAKENHI-PROJECT-17K10014
  • [Presentation] 赤内型マラリア原虫は宿主血小板由来エクソソームを介して脂質受容体CD36を供給され 、増殖に必要なステロールを宿主HDLから取り込む2020

    • Author(s)
      磯尾直之、徳舛富由樹、小松谷啓介、北潔
    • Organizer
      第89回日本寄生虫学会大会
    • Data Source
      KAKENHI-PROJECT-17K10014
  • [Presentation] 赤内型マラリア原虫はエクソソームを介して宿主血小板由来スカベンジャー受容体CD36を輸送され宿主HDLを取り込む2018

    • Author(s)
      磯尾 直之、小松谷 啓介、徳舛 富由樹、原 眞純 、北 潔
    • Organizer
      日本動脈硬化学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-17K10014
  • [Presentation] 赤内型マラリア原虫はエクソソームを介して宿主血小板由来スカベンジャー受容体CD 36を輸送され宿主HDLを取り込む2018

    • Author(s)
      磯尾 直之
    • Organizer
      第50回日本動脈硬化学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-17K10014
  • [Presentation] ポリアクリルアミドゲル電気泳動によるマラリア患者リポ蛋白解析2016

    • Author(s)
      磯尾 直之
    • Organizer
      第67回日本電気泳動学会総会
    • Place of Presentation
      釧路市観光国際交流センター
    • Year and Date
      2016-08-26
    • Data Source
      KAKENHI-PROJECT-26461499
  • [Presentation] ポリアクリルアミドゲル電気泳動によるマラリア患者リポ蛋白解析2016

    • Author(s)
      磯尾 直之、石垣 知寛、菊地 正、安達 英輔、古賀 道子、鯉渕 智彦
    • Organizer
      第67回日本電気泳動学会総会(2016) シンポジウム講演
    • Place of Presentation
      釧路市観光国際交流センター
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461499
  • 1.  磯尾 紀子 (90548330)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 2.  TSUKAMOTO Kazuhisa (20251233)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  MORIYA Kyouji (00272550)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  FUJIE Hajime (90332577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  NAKAOKA Takashi (80241256)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TOMITA Sachiko (40231451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KITA Kiyoshi (90134444)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  HARA Masumi (70420213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  WATANABE Takuro (20376437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ISHIZAKA Nobukazu (20270879)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Watanabe Atai (00597271)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  YAMASHITA Naohide (90174680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TOJO Arinobu (00211681)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  OHNO Hideki (30396866)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  林 俊宏 (60505890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  伊藤 弦太 (10431892)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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