AOI Noriaki 青井典明

… Alternative Names

青井典明アオイノリアキ

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Researcher Number	80452556
Affiliation (Current)	2025: 島根大学, 学術研究院医学・看護学系, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 島根大学, 学術研究院医学・看護学系, 准教授 2016 – 2017: 島根大学, 医学部, 准教授 2011 – 2015: 島根大学, 医学部, 講師 2007 – 2009: 島根大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology Except Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator Toll様受容体 / アレルギー性鼻炎 / 舌下免疫療法 / アレルギー性鼻炎の制御 Except Principal Investigator 舌下免疫療法 / アレルギー性鼻炎 / スギ花粉症治療米 / スギ花粉症 / 経口免疫療法 / 調節性T細胞 … More / マスト細胞 / 免疫療法 / 粘膜アジュバント / maternal immunization / 蛋白顆粒 / 免疫学的パラメーター / 好酸球浸潤 / 鼻症状 / マウススギ花粉症モデル / 経口自然摂取 / 気道上皮細胞 / Th2型サイトカイン / 抗ヒスタミン薬 / 経口免疫寛容 / 花粉症治療米 / 経口免疫 / Ｔ細胞エピトープ / 調整性Ｔ細胞 / 免疫学的寛容 / protein body / サイトカイン / 抗原提示細胞 / 制御性T細胞 / ＣＴＢ / 調節性Ｔ細胞 / コレラトキシン / IgE抗体 / ＩｇＥ抗体 / regulatory T cells / ｽｷﾞ花粉症治療米 / ｽｷﾞ花粉症 / Tg mice / IL-15 / Toll-like receptor / CD4陽性CD25陽性制御性T細胞 / CD4陽性CD25要請制御性T細胞 / Foxp3 Less

Toll様受容体を介した舌下免疫療法の増強Principal Investigator
- Principal Investigator
  
  青井典明
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Shimane University
Safetyness and efficacy of mucosal route of immunotherapy with transgenic rice seads containing whole T cell epitopes of Cryj1 and Cryj2 for patients with japanese cedar pollinosis
- Principal Investigator
  
  Kawauchi Hideyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Shimane University
Development of sublingual immunotherapy with Transgenic rice seeds in patients with cedar pollinosisi
- Principal Investigator
  
  hideyuki kawauchi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Shimane University
The Effect of Toll-like receptor on Allergic Rhinitis in Murine Model.Principal Investigator
- Principal Investigator
  
  Noriaki Aoi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Shimane University
Mechanism of sublingual immunotherapy -experimental approach in murine model-
- Principal Investigator
  
  KAWAUCHI Hideyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Shimane University
Downregulation of nasal symptoms in patients with allergic rhinitis-Immunological study in mice and human materials-
- Principal Investigator
  
  KAWAUCHI Hideyuki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Shimane University

[Book] Sublingual Immunotherapy Induces Regulatory Function of IL-10-Expressing CD4(+)CD25(+)Foxp3(+) T Cells of Cervical Lymph Nodes in Murine Allergic Rhinitis Model.2012
- Author(s)
  Takaya Yamada, Miki Tongu, Kaoru Goda, Noriaki Aoi, Ichiro Morikura, Takafumi Fuchiwaki, Hideyuki Kawauchi
- Publisher
  Journal of Allergy
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] Sublingual immunotherapy induces regulatory function of IL-10 producing T cellsof cervical lymph nodes and actually attenuates nasal symptoms upon allergen exposure in murine allergic rhinitis model2021
- Author(s)
  Yinfei Qu, Yukie Tamura, Takaya Yamada, Noriaki Aoi, Ichiro Morikura, Takashi Fuchiwaki, Hideyuki Kawauchi
- Journal Title
  
  Proceedings of 5th Rhinology Research Forum in Asia
  
  Volume: 1 Pages: 41-44
- Data Source
  KAKENHI-PROJECT-20K09712
[Journal Article] Efficient Mucosal route of immunotherapy with Transgenic rice Seeds expressing Hypoallergenic Whole T Cell Epitopes of Cryj1 and Cryj2 -An investigation in Murine Model of Cedar Pollinosis at eliciting phase-2021
- Author(s)
  Takaya Yamada, Yinfei Qu, Noriaki Aoi, Hidenori Takagi, Fumio Takaiwa, Ichiro Morikura, Takashi Fuchiwaki, Yukie Tamura, Hideyuki Kawauchi
- Journal Title
  
  Proceedings of 5th Rhinology Research Forum in Asia
  
  Volume: 1 Pages: 45-48
- Data Source
  KAKENHI-PROJECT-20K09712
[Journal Article] Nasal Administration of Lipopolysaccharide Exacerbates Allergic Rhinitis through Th2 Cytokine Production from Mast Cells2021
- Author(s)
  Noriaki Aoi, Takafumi Fuchiwaki, Ichiro Morikura, Hideyuki Kawauchi, Tatsunori Sakamoto
- Journal Title
  
  Allergies
  
  Volume: 1（4） Issue: 4 Pages: 216-224
- DOI
  10.3390/allergies1040020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09712
[Journal Article] Mucosal immunity of middle ear and nasopharynx2021
- Author(s)
  Hideyuki Kawauchi, Noriaki Aoi, Ichiro Morikura, Yasuhiko Shimizu, Takafumi Fuchiwaki, Kanako Shimizu, Yukie Hotta, Infei Qu, Takaya Yamada, Fumio Takaiwa
- Journal Title
  
  Proceedings of 5th Rhinology Research Forum in Asia
  
  Volume: 1 Pages: 15-24
- Data Source
  KAKENHI-PROJECT-20K09712
[Journal Article] Efficient Mucosal route of immunotherapy with Transgenic rice Seeds2018
- Author(s)
  H Kawauchi, T Yamada, Y Qu, N Aoi, H Takagi
- Journal Title
  
  日本耳鼻咽喉科免疫アレルギー学会会誌
  
  Volume: in press Pages: 000-000
- Open Access
- Data Source
  KAKENHI-PROJECT-15K15618
[Journal Article] Japanese traditional medicine, Senn-kinn-naidaku-sann upregulates Toll-like receptor 4 and reduce murine allergic rhinitis2014
- Author(s)
  Ichiro Morikura, Akemichi Murata, Noriaki Aoi, Yasuhiko Shimizu, Morikura, Akemichi Murata, Noriaki Aoi, Yasuhiko Shimizu, Takafumi Fuchiwaki, Emmanuel Prokopakis Murata, Noriaki Aoi, Yasuhiko Shimizu, Takafumi Fuchiwaki, Emmanuel Prokopakis, HIdeyuki Kawauchi
- Journal Title
  
  Rhinology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] 気道の炎症病態におけるToll様受容体（Toll-like receptor）の役割と臨床的意義2014
- Author(s)
  川内秀之、青井典明、森倉一朗、清水保彦、清水加奈子、淵脇貴史１、堀田優希江、屈　銀斐、山田高也
- Journal Title
  
  島根医学
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] Effects of the Japanese traditional medicine Bu-zhong-yi-qi-tang on Th2 responsesvia up-regulation of Toll-like receptor 42013
- Author(s)
  Yasuhiko Shimizu, Noriaki Aoi, Ichiro Morikura, Takafumi Fuchiwaki, Hideyuki Kawauchi
- Journal Title
  
  ARSR Journal 2013
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] マウス舌下免疫療法モデルにおける頸部リンパ節IL-10 産生制御性T 細胞の誘導2013
- Author(s)
  屈　　銀斐,頓宮　美樹, 田村優希江、山田高也、青井典明、森倉一朗、淵脇貴史、川内秀之
- Journal Title
  
  耳鼻免疫アレルギー
  
  Volume: 31(2) Pages: 49-50
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] マウス舌下免疫療法モデルにおける頸部リンパ節IL-10産生制御性T細胞の誘導2013
- Author(s)
  屈銀斐、頓宮美樹、田村優希江、山田高也、青井典明、森倉一朗、淵脇貴史、川内秀之
- Journal Title
  
  耳鼻免疫アレルギー
  
  Volume: 31(2) Pages: 49-50
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] Oral Administration of Fexofenadine Hydrochloride can Attenuate Nasal Symptoms and Restore the Impaired Cognitive Function in School-Age Patients With Japanese Cedar Pollinosis2013
- Author(s)
  Noriaki AOI, Yasuhiko SHIMIZU, Ichiro MORIKURA, Knanako SHIMIZU, Takafumi FUCHIWAKI, Yukie TAMURA, Keisuke SANO, Mitsuhiro KIMURA, Akemichi MURATA, Hideyuki KAWAUCHI
- Journal Title
  
  Shimane J. Med. Sci.
  
  Volume: 29 Pages: 79-86
- NAID
  110009591609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] Oral Administration of Fexofenadine Hydrochloride can Attenuate Nasal Symptoms and Restore the Impaired Cognitive Function in School-Age Patients With Japanese Cedar Pollinosis2013
- Author(s)
  Noriaki AOI, Yasuhiko SHIMIZU, Ichiro MORIKURA, Knanako SHIMIZU, Takafumi FUCHIWAKI, Yukie TAMURA, Keisuke SANO, Mitsuhiro KIMURA, Akemichi MURATA, Hideyuki KAWAUCHI
- Journal Title
  
  Shimane J. Med. Sci
  
  Volume: Vol.29 Pages: 79-86
- NAID
  110009591609
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] Effects of the Japanese traditional medicine Bu-zhong-yi-qi-tang on Th2 responsesvia up-regulation of Toll-like receptor 42013
- Author(s)
  Yasuhiko Shimizu,Noriaki Aoi,Ichiro Morikura,TakahfumiFuchiwaki,Hideyuki Kawauchi
- Journal Title
  
  ARSR journal
  
  Volume: １ Pages: 42-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] Sublingual immunotherapy induces regulatory function of IL-10 expressing CD4^+CD25^+Foxp^<3+> T cells of cervical lymph nodes in murine allergic rhinitis model2012
- Author(s)
  Takaya Yamada, Miki Tongu, Kaoru Goda, Noriaki Aoi, Ichiro Morikura, Takafumi Fuchiwaki and Hideyuki Kawauchi
- Journal Title
  
  J Allergy
  
  Volume: (Article ID 490905) Pages: 11-11
- DOI
  10.1155/2012/490905
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] Japanese traditional medicine, Senn-kinn-naidaku-sann up-regulates Toll-like receptor 4 and reduces murine allergic rhinitis2012
- Author(s)
  Ichiro Morikuraa, Akemichi Murataa,, Noriaki Aoia, Yasuhiko Shimizua, Takafumi Fuchiwakia,, Emmanuel prokopakisb,Hideyuki Kawauchia
- Journal Title
  
  Rhinology, In Press
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] Short Review on Sublingual Immunotherapy for Patients with Allergic Rhinitis2011
- Author(s)
  Hideyuki Kawauchi, Kaoru Goda, Miki Tongu , Takaya Yamada, Noriaki Aoi, Ichiro Morikura , Takashi Fuchiwaki
- Journal Title
  
  Adv Otorhinolaryngol
  
  Volume: 72 Pages: 103-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] Short review on sublingual immunotherapy for patients with allergic rhinitis : from bench to bedside2011
- Author(s)
  Hideyuki Kawauchi, Kaoru Goda, Miki Tongu, Takaya Yamada, Noriaki Aoi, Ichiro Morikura, Takashi Fuchiwaki
- Journal Title
  
  Advances in Oto-Rhino-Laryngology
  
  Volume: 72 Pages: 103-6
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] 鼻アレルギー制御を目的とした粘膜免疫の臨床応用.2009
- Author(s)
  川内秀之, 青井典明, 村田明道, 合田薫, 森倉一朗, 山田高也
- Journal Title
  
  アレルギー 58(2)
  
  Pages: 103-111
- NAID
  110007161219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390434
[Journal Article] 鼻アレルギー制御を目的とした粘膜免疫の臨床応用2009
- Author(s)
  川内秀之, 青井典明, 村田明道, 合田薫, 森倉一朗, 山田高也
- Journal Title
  
  アレルギー 58(2)
  
  Pages: 103-111
- NAID
  110007161219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390434
[Journal Article] サイトカインによるアレルギー治療2008
- Author(s)
  青井典明, 吉開泰信, 川内秀之
- Journal Title
  
  耳鼻咽喉科展望 51(Suppl.1)
  
  Pages: 43-47
- NAID
  130004911622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390434
[Journal Article] アレルギー治療薬の免疫修飾作用に関する基礎的検討.2008
- Author(s)
  川内秀之, 青井典明, 清水保彦, 合田薫, 佐野千晶, 片岡真吾, 山田高也
- Journal Title
  
  耳鼻咽喉科免疫アレルギー 26(2)
  
  Pages: 142-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390434
[Journal Article] スギ花粉症におけるロイコトリエン受容体拮抗薬(プランルカスト)の有用性の検討2008
- Author(s)
  清水保彦, 片岡真吾, 青井典明, 村田明道, 木村光宏, 佐野千晶, 佐野啓介, 川内秀之
- Journal Title
  
  耳鼻咽喉科免疫アレルギー 26(1)
  
  Pages: 23-29
- NAID
  10021295249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390434
[Journal Article] アレルギー性鼻炎・花粉症の病態解明と治療戦略の確立-環境衛生仮説から遺伝子治療まで-2008
- Author(s)
  川内秀之, 青井典明, 片岡真吾, 村田明道, 山田高也
- Journal Title
  
  耳鼻咽喉科展望 51(1)
  
  Pages: 8-25
- NAID
  130004546219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390434
[Journal Article] 鼻粘膜における局所免疫応答機構の解析-サイトカイン産生とメモリーT細胞に関する検討-2008
- Author(s)
  頓宮美樹, 山田高也, 青井典明, 佐野千晶, 片岡真吾, 川内秀之
- Journal Title
  
  耳鼻咽喉科免疫アレルギー 26(2)
  
  Pages: 66-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390434
[Journal Article] 通年性アレルギー鼻炎患者を対象としたロラタジンの服用時期の違いによる有用性の検討2007
- Author(s)
  川内秀之, 片岡真吾, 佐野千晶, 木村光宏, 青井典明, 清水保彦, 梅原毅, 森倉一朗, 合田薫, 淵脇貴史, 加藤洋平
- Journal Title
  
  Progress in Medicine 27(11)
  
  Pages: 2615-2623
- Data Source
  KAKENHI-PROJECT-19390434
[Journal Article] Japanese traditional medicine, Senn-kinn-naidaku-sann up-regulates Toll-like receptor 4 and reduces murine allergic rhinitis
- Author(s)
  Ichiro Morikura, Akemichi Murata, Hisashi Ohga, Kaoru Goda, Noriaki Aoi, Shingo Kataoka, Hideyuki Kawauchi
- Journal Title
  
  Rhinology
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23659796
[Journal Article] サイトカインによるアレルギー治療
- Author(s)
  青井典明
- Journal Title
  
  耳鼻咽喉科展望 (印刷中)
- NAID
  130004911622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390434
[Presentation] Immunotherapy for allergic rhinitis -past, present, and future2023
- Author(s)
  Hideyuki Kawauchi, Noriaki Aoi, Ichiro Morikura, Fumio Takaiwa
- Organizer
  13th International symposium on recent advances in rhinosinusitis and nasal polyposis, Sibiu, Romania
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09712
[Presentation] Future-coming antigen-specific immunotherapy (IT) for patients with allergic rhinitis: mucosal route of IT (sublingual or per os) or regional intralymphatic IT(ILIT), using high dose of allergenic epitopes delivery system2023
- Author(s)
  Hideyuki Kawauchi, Noriaki Aoi, Ichiro Morikura, Fumio Takaiwa
- Organizer
  29th European rhinologic society meeting & ISIAN 2023 Sofia, Bulgaria
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09712
[Presentation] Efficient mucosal route of Immunotherapy with transgenic rice seeds expressing hypoallergenic whole T cell epitopes of Cryj1 and Cryj2 - an investigation in murine model of cedar pollinosis at eliciting phase -2022
- Author(s)
  Hideyuki Kawauchi, Noriaki Aoi, Ichiro Morikura, Takaya Yamada, Fumio Takaiwa
- Organizer
  ORLIAC 2022 Rome
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09712
[Presentation] Innovative mucosal route of immunotherapy with trangenic rice seeds containing Cryj1 and Cryj2 T cell epitopes2021
- Author(s)
  Hideyuki Kawauchi, Takaya Yamada, Hisashi Iizasa, Noriaki Aoi , Fumio Takaiwa
- Organizer
  28thEuropean Rhinologic Society annual meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09712
[Presentation] Efficient mucosal route of immunotherapy with transgenic rice seeds expressing hypoallergenic whole T cell epitopes of Cryj1 and Cryj22021
- Author(s)
  Hideyuki Kawauchi, Noriaki Aoi, Takaya Yamada, Hisashi Iizasa Ichiro Morikura,
- Organizer
  5th Rhinologic Research Forum in Asia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09712
[Presentation] mucosal route of immunotherapy with transgenic rice seeds containing Cryj1 and Cryj2 T cell epotopes2020
- Author(s)
  川内秀之、山田高也、飯笹　久、青井典明、森倉一朗
- Organizer
  第59回日本鼻科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09712
[Presentation] スギ花粉症治療米の蛋白顆粒を用いた経粘膜的投与によるスギ花粉症鼻症状の抑制-マウススギ花粉症モデルでの実験的検討-2018
- Author(s)
  川内秀之,山田高也, 青井典明、高岩文雄
- Organizer
  日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-15K15618
[Presentation] Mucosal Route OF Immunotherapy with Transgenic Rice Seeds Expressing Whole T Cell Epitopes of Cryj1 and Cryj2-an experimental study in murine cedar pollinosis model-2018
- Author(s)
  Hideyuki Kawauchi, Noriaki Aoi, Ichiro, Morikura, Takafumi Fuchiwaki, Takaya Yamada, Fumio Takaiwa
- Organizer
  27ｔｈ　Ｅｕｒｏｐｅａｎ　Ｒｈｉｎｏｌｏｇｉｃ　Ｓｏｃｉｅｔｙ　ｍｅｅｔｉｎｇ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15618
[Presentation] リポ多糖によるマウスアレルギー性鼻炎モデルの反応相の修飾2017
- Author(s)
  青井典明
- Organizer
  第35回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  旭川
- Year and Date
  2017-04-15
- Data Source
  KAKENHI-PROJECT-26861386
[Presentation] スギ花粉症治療米を用いた経粘膜的免疫療法の有効性の実験的検討2016
- Author(s)
  川内秀之、青井典明、森倉一朗、淵脇貴史
- Organizer
  第55回日本鼻科学会総会ならびに学術講演会
- Place of Presentation
  宇都宮市、栃木県
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-15K15618
[Presentation] マウスアレルギー性鼻炎モデルにおける舌下免疫療法の有用性と機序の検討2013
- Author(s)
  屈銀斐、田村優希江、山田高也、青井典明、森倉一朗、淵脇貴史、川内秀之
- Organizer
  第52回日本鼻科学会総会・学術講演会
- Place of Presentation
  福井市
- Year and Date
  2013-09-28
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] マウス舌下免疫療法モデルにおける頸部リンパ節IL-10 産生制御性T 細胞の誘導2013
- Author(s)
  屈銀斐、田村優希江、青井典明、森倉一朗、淵脇貴史、川内秀之
- Organizer
  日本耳鼻咽喉科学会第39回中国四国地方部会連合学会
- Place of Presentation
  高知
- Year and Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] Sublingual immunotherapy induces regulatory function of IL-10 expressing CD4^+ CD25^+ Foxp3^+ T cells of cervical lymph nodes and actually attenuates nasal symptoms upon allergen exposure in murine allergic rhinitis model2013
- Author(s)
  Yin Fei Qu, Miki Tongu, Yukie Tamura, Takaya Yamada, Noriaki Aoi, Ichiro Morikura, Takafumi Fuchiwaki, Hideyuki Kawauchi
- Organizer
  第31回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  倉敷市
- Year and Date
  2013-02-08
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] 肥満細胞の脱顆粒とサイトカイン産生に及ぼすH1受容体拮抗薬の作用2012
- Author(s)
  清水香奈子，青井典明，清水保彦，川内秀之
- Organizer
  第24回日本アレルギー学会春季臨床大会
- Place of Presentation
  （大阪市）大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] アレルギー性鼻炎におけるCD30 ligand の役割2012
- Author(s)
  淵脇貴史,森倉一朗,青井典明,吉開泰信,川内秀之
- Organizer
  第30回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  大津市
- Year and Date
  2012-02-18
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] スギ花粉症治療米の舌下投与によるマウススギ花粉症モデルでの症状抑制効果の検討2012
- Author(s)
  川内秀之,屈銀斐,頓宮美樹,山田高也,田村優希江,青井典明,淵脇貴史
- Organizer
  第51回日本鼻科学会総会・学術講演会
- Place of Presentation
  千葉市
- Year and Date
  2012-09-29
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] Sublingual immunotherapy with a rice-based edible vaccine expressing cedar pollen multiple T cell epitopes attenuates the nasal symptoms in murine allergic rhinitis model with pollinosis2012
- Author(s)
  Kawauchi, H, Yamada T, Tongu M, Aoi, N, Takagi H, Takaiwa F
- Organizer
  European Academy of Allergy and Clinical Immunology Congress 2012 Geneve
- Place of Presentation
  Switzerland
- Year and Date
  2012-06-17
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] リポプロテイン刺激による上皮細胞からのIL-8産生における抗ヒスタミン薬の抑制効果と臨床的意義2012
- Author(s)
  清水保彦，青井典明，清水香奈子，淵脇貴史，森倉一朗，川内秀之
- Organizer
  第16回日本ヒスタミン学会
- Place of Presentation
  (岡山)岡山プラザホテル
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] In Vitro Mast Cell Regulation with H1 Receptor Antagonists2012
- Author(s)
  Kanako Shimizu, Noriaki Aoi, Yasuhiko Shimizu, Hideyuki Kawauchi
- Organizer
  15th ASIAN RESEARCH SYMPOSIUM IN RHINOLOGY
- Place of Presentation
  （singapore)ORCHARDHOTEL
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] The Central Role of CD30L/CD30 Interactions in Allergic Rhinitis Pathogenesis in Mice2011
- Author(s)
  Takafumi Fuchiwaki, Xun Sun, Noriaki Aoi, Yasunobu Yoshikai, Hideyuki Kawauchi
- Organizer
  IRS & ISIAN 2011
- Place of Presentation
  Tokyo
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] マウス用スギ花粉治療米を用いた舌下免疫療法の有効性の検討2011
- Author(s)
  川内秀之,山田高也,頓宮美樹,青井典明,森倉一朗,淵脇貴史,高岩文雄
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京都
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] マウスアレルギー性鼻炎モデルを用いた舌下免疫療法の有効性と作用機序の検討2011
- Author(s)
  川内秀之、青井典明
- Organizer
  第23回日本アレルギー学会春季大会
- Place of Presentation
  （千葉市）幕張メッセ
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] マウス用スギ花粉治療米を用いた舌下免疫療法の有効性の検討2011
- Author(s)
  1169.川内秀之，山田高也，頓宮美樹，青井典明，森倉一朗，淵脇貴史，高岩文雄
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  （東京）グランドプリンスホテル新高輪　国際館パミール
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] マウスアレルギー性鼻炎モデルを用いた舌下免疫療法の有効性と作用機序の検討2011
- Author(s)
  川内秀之,青井典明
- Organizer
  第23回日本アレルギー学会春季臨床大会
- Place of Presentation
  千葉市
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] 鼻粘膜のアレルギー性炎症におけるToll様受容体の役割-アレルギー性鼻炎マウスモデルでの実験的検討-2009
- Author(s)
  青井典明
- Organizer
  第48回日本鼻科学会総会・学術講演会
- Place of Presentation
  松江市
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19390434
[Presentation] 鼻粘膜のアレルギー性炎症におけるToll様受容体の役割 -アレルギー性鼻炎マウスモデルでの実験的検討-2009
- Author(s)
  青井典明
- Organizer
  第48回日本鼻科学会総会・学術講演会
- Place of Presentation
  松江市
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19390434
[Presentation] プランルカストによるスギ花粉症初期療法の有用性の検討2009
- Author(s)
  青井典明
- Organizer
  第21回日本アレルギー学会春季臨床大会
- Place of Presentation
  岐阜市
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-19390434
[Presentation] アレルギー性炎症の制御を目的とした粘膜免疫の臨床応用2009
- Author(s)
  青井典明
- Organizer
  第17回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  千葉市
- Year and Date
  2009-02-13
- Data Source
  KAKENHI-PROJECT-19390434
[Presentation] Intranasal cytokine therapy for attenuating nasal allergic symptoms2008
- Author(s)
  Noriaki Aoi
- Organizer
  12^<th> International Seminar Otorhinolaryngology in Shimane (第80回日本耳鼻咽喉科学会島根県地方部会学術講演会)
- Place of Presentation
  松江市
- Year and Date
  2008-09-22
- Data Source
  KAKENHI-PROJECT-19390434
[Presentation] アレルギー性鼻炎の病態における肥満細胞の役割と細菌感染による修飾(肥満細胞の機能発現におけるToll-like receptorの関与)2007
- Author(s)
  青井典明
- Organizer
  第8回中四国耳鼻咽喉科アレルギー疾患研究会
- Place of Presentation
  高松市
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-19390434
[Presentation] サイトカインによるアレルギー制御2007
- Author(s)
  青井典明
- Organizer
  第31回日本医用エアロゾル研究会
- Place of Presentation
  旭川市
- Year and Date
  2007-09-22
- Data Source
  KAKENHI-PROJECT-19390434
[Presentation] マウス舌下免疫療法モデルにおける頸部リンパ節IL-10産生制御性T細胞の誘導
- Author(s)
  川内秀之、屈銀斐、田村優希江、青井典明、森倉一朗、淵脇貴史
- Organizer
  日本耳鼻咽喉科学会第３９回中国四国地方部会連合学会
- Place of Presentation
  高知県民会館
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] マウス舌下免疫モデルにおける臨床症状と頸部リンパ節T細胞の誘導
- Author(s)
  田村優希江、森倉一朗、淵脇貴史、青井典明、川内秀之
- Organizer
  第26回日本口腔・咽頭科学会総会　学術講演会
- Place of Presentation
  名古屋市全日空ホテル
- Data Source
  KAKENHI-PROJECT-23659796
[Presentation] マウスアレルギー性鼻炎モデルにおける舌下免疫療法の有用性と機序の検討
- Author(s)
  屈銀斐、田村優希江、山田高也、青井典明、森倉一朗、淵脇貴史、川内秀之
- Organizer
  第52回日本鼻科学会総会・学術講演会
- Place of Presentation
  福井県民会館
- Data Source
  KAKENHI-PROJECT-23659796

1. KAWAUCHI Hideyuki (50161279)

# of Collaborated Projects: 4 results

# of Collaborated Products: 53 results
2. MORIKURA Ichiro (00362939)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
3. YAMADA Takaya (50191317)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. 飯笹久 (80306662)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 淵脇貴史 (10437543)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. KATAOKA Shingo (60152667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. SANO Chiaki (70325059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 坂本達則 (60425626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AOI Noriaki 青井 典明

青井 典明 アオイ ノリアキ

Research Projects

Research Products

Co-Researchers

Toll様受容体を介した舌下免疫療法の増強Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Safetyness and efficacy of mucosal route of immunotherapy with transgenic rice seads containing whole T cell epitopes of Cryj1 and Cryj2 for patients with japanese cedar pollinosis

Principal Investigator

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Review Section

Research Institution

Development of sublingual immunotherapy with Transgenic rice seeds in patients with cedar pollinosisi

Principal Investigator

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Research Field

Research Institution

The Effect of Toll-like receptor on Allergic Rhinitis in Murine Model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of sublingual immunotherapy -experimental approach in murine model-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Downregulation of nasal symptoms in patients with allergic rhinitis-Immunological study in mice and human materials-

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Book] Sublingual Immunotherapy Induces Regulatory Function of IL-10-Expressing CD4(+)CD25(+)Foxp3(+) T Cells of Cervical Lymph Nodes in Murine Allergic Rhinitis Model.2012

Author(s)

Publisher

Data Source

[Journal Article] Sublingual immunotherapy induces regulatory function of IL-10 producing T cellsof cervical lymph nodes and actually attenuates nasal symptoms upon allergen exposure in murine allergic rhinitis model2021

Author(s)

Journal Title

Data Source

[Journal Article] Efficient Mucosal route of immunotherapy with Transgenic rice Seeds expressing Hypoallergenic Whole T Cell Epitopes of Cryj1 and Cryj2 -An investigation in Murine Model of Cedar Pollinosis at eliciting phase-2021

Author(s)

Journal Title

Data Source

[Journal Article] Nasal Administration of Lipopolysaccharide Exacerbates Allergic Rhinitis through Th2 Cytokine Production from Mast Cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mucosal immunity of middle ear and nasopharynx2021

Author(s)

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Data Source

[Journal Article] Efficient Mucosal route of immunotherapy with Transgenic rice Seeds2018

Author(s)

Journal Title

Data Source

[Journal Article] Japanese traditional medicine, Senn-kinn-naidaku-sann upregulates Toll-like receptor 4 and reduce murine allergic rhinitis2014

Author(s)

Journal Title

Data Source

[Journal Article] 気道の炎症病態におけるToll様受容体（Toll-like receptor）の役割と臨床的意義2014

Author(s)

Journal Title

Data Source

[Journal Article] Effects of the Japanese traditional medicine Bu-zhong-yi-qi-tang on Th2 responsesvia up-regulation of Toll-like receptor 42013

Author(s)

Journal Title

Data Source

[Journal Article] マウス舌下免疫療法モデルにおける頸部リンパ節IL-10 産生制御性T 細胞の誘導2013

Author(s)

AOI Noriaki 青井典明

青井典明アオイノリアキ