Nishimura Ken 西村健

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NISHIMURA Ken 西村健

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Researcher Number	80500610
Other IDs
Affiliation (Current)	2025: 筑波大学, 医学医療系, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 筑波大学, 医学医療系, 教授 2017 – 2022: 筑波大学, 医学医療系, 准教授 2011 – 2016: 筑波大学, 医学医療系, 助教
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 43010:Molecular biology-related / Basic Section 43050:Genome biology-related / Medium-sized Section 90:Biomedical engineering and related fields / Molecular biology / Biomedical engineering/Biological material science Except Principal Investigator General medical chemistry / Medium-sized Section 48:Biomedical structure and function and related fields / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 48040:Medical biochemistry-related / Molecular and Genome biology and related fields / Pathological medical chemistry / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator iPS細胞 / エピジェネティクス / Klf4 / 量依存性 / 転写因子 / miRNA / SeVdpベクター / Nanog / X染色体再活性化 / KLF4 … More / 転写 / エピゲノム / 多能性 / 転写制御 / 分化促進遺伝子 / 分化細胞 / 神経幹細胞 / 自動除去型SeVdpベクター / 創薬 / 再生医療 / 分化誘導 / 3S reprogramming system / 再活性化 / SNP / X染色体 / 発現量依存的 / Tcl1 / 安全性 / 持続発現型RNAベクター / 残存未分化細胞 / 多能性幹細胞 / 分化 / 未分化細胞除去 / 神経分化 / 持続発現型ベクター … More Except Principal Investigator iPS細胞 / リプログラミング / サイレンシング / クロマチン / 間葉上皮転換 / 転写因子 / Klf4 / 転写制御 / XCR / レトロウイルス / 再生医学 / 代謝変換 / センダイウイルス / iPS 細胞 / 遺伝子発現 / 多能性 / RNA / 翻訳制御 / 細胞外小胞 / 肝硬変 / マクロファージ / 間葉系幹細胞 / エクソソーム / Xist / RNA-seq / 転写 / E2F / Osr2 / KLF4 / X染色体の再活性化 / リプリログラミング / INHAT / uORF / エピゲノム / アポトーシス / X 染色体 / EMT / 細胞分化 / 間葉上皮変換 / MET / X染色体 / 代謝 / DNA変異 / MitoTracker / ROS / 酸化的リン酸化 / Tcl1 / 解糖系 / 活性酸素 / ミトコンドリア / ゲノム編集 / ベージュ脂肪組織 / 褐色脂肪組織 / 蛍光イメージング / iRFP / Ucp1 / イメージング / ベージュ脂肪細胞 / 褐色脂肪細胞 / UCP1 / 非染色 / CARS / ラマン / 細胞初期化 / エピジェネティクス / 遺伝子発現制御 Less

Mechanistic analysis of translation-based silencing of exogenous RNA
- Principal Investigator
  
  久武幸司
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  University of Tsukuba
Cell fate decision by dose of transcription factorsPrincipal Investigator
- Principal Investigator
  
  西村健
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  University of Tsukuba
Development of liver regeneration therapy using super exosomes with multiple and high volume protein delivery systems
- Principal Investigator
  
  Tsuchiya Atsunori
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Niigata University
Mechanistic analysis of somatic cell reprogramming using paused iPSCs
- Principal Investigator
  
  Hisatake Koji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  University of Tsukuba
Safe and efficient selection of differentiated cells by stage-specific gene expression from auto-erasable vectorPrincipal Investigator
- Principal Investigator
  
  Nishimura Ken
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  University of Tsukuba
Molecular dynamics of epigenomic transcriptional regulation by Klf4 in iPSC generationPrincipal Investigator
- Principal Investigator
  
  Nishimura Ken
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  University of Tsukuba
A Tcl1-mediated method to generate iPSCs with reduced genomic mutations
- Principal Investigator
  
  Hisatake Koji
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Molecular and Genome biology and related fields
- Research Institution
  University of Tsukuba
Reprogramming of cell morphology and functions by Klf4 during iPSC generation
- Principal Investigator
  
  Hisatake Koji
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba
Spatially and time-dependent analysis of initial phase of epigenetic regulation in X chromosome reactivationPrincipal Investigator
- Principal Investigator
  
  Nishimura Ken
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  University of Tsukuba
Non-invasive imaging of UCP1 expression in live mice
- Principal Investigator
  
  Fukuda Aya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Tsukuba
Development of novel molecular imaging method for visualizing pluripotency of iPS cells
- Principal Investigator
  
  KANO Hideaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  University of Tsukuba
Mechanistic analysis of iPSC production using paused iPSCPrincipal Investigator
- Principal Investigator
  
  Nishimura Ken
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba
Analysis of the transcription factor network during the early stage of iPSC production
- Principal Investigator
  
  Hisatake Koji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba
Establishment of safe and efficient differentiation system using automatic removal vectorPrincipal Investigator
- Principal Investigator
  
  NISHIMURA Ken
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  University of Tsukuba
細胞質持続発現型RNAベクターを用いた高効率かつ安全な分化誘導方法の確立Principal Investigator
- Principal Investigator
  
  西村健
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis2023
- Author(s)
  Takeda Nobutaka、Tsuchiya Atsunori、Mito Masaki、Natsui Kazuki、Natusi Yui、Koseki Yohei、Tomiyoshi Kei、Yamazaki Fusako、Yoshida Yuki、Abe Hiroyuki、Sano Masayuki、Kido Taketomo、Yoshioka Yusuke、Kikuta Junichi、Itoh Tohru、Nishimura Ken、Ishii Masaru、Ochiya Takahiro、Miyajima Atsushi、Terai Shuji
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 43 Issue: 1 Pages: 48-48
- DOI
  10.1186/s41232-023-00299-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19423, KAKENHI-PROJECT-22K19933, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02518, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-23K24128
[Journal Article] Locus-Specific Isolation of the Nanog Chromatin Identifies Regulators Relevant to Pluripotency of Mouse Embryonic Stem Cells and Reprogramming of Somatic Cells2022
- Author(s)
  Burramsetty Arun Kumar、Nishimura Ken、Kishimoto Takumi、Hamzah Muhammad、Kuno Akihiro、Fukuda Aya、Hisatake Koji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 23 Pages: 15242-15242
- DOI
  10.3390/ijms232315242
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02678
[Journal Article] Downregulation of Odd-Skipped Related 2, a Novel Regulator of Epithelial-Mesenchymal Transition, Enables Efficient Somatic Cell Reprogramming2022
- Author(s)
  Anh Le Phuong Hoang、Nishimura Ken、Kuno Akihiro、Linh Nguyen Thuy、Kato Tetsuo、Ohtaka Manami、Nakanishi Mahito、Sugihara Eiji、Sato Taka-Aki、Hayashi Yohei、Fukuda Aya、Hisatake Koji
- Journal Title
  
  Stem Cells
  
  Volume: 40 Issue: 4 Pages: 397-410
- DOI
  10.1093/stmcls/sxac012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02678, KAKENHI-PROJECT-19H03203
[Journal Article] Structurally-discovered KLF4 variants accelerate and stabilize reprogramming to pluripotency2022
- Author(s)
  Borisova Evgeniia、Nishimura Ken、An Yuri、Takami Miho、Li Jingyue、Song Dan、Matsuo-Takasaki Mami、Luijkx Dorian、Aizawa Shiho、Kuno Akihiro、Sugihara Eiji、Sato Taka-aki、Yumoto Fumiaki、Terada Tohru、Hisatake Koji、Hayashi Yohei
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 1 Pages: 103525-103525
- DOI
  10.1016/j.isci.2021.103525
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02678, KAKENHI-PROJECT-19H03203
[Journal Article] Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming2022
- Author(s)
  Aizawa Shiho、Nishimura Ken、Mondejar Gonzalo Seminario、Kumar Arun、Bui Phuong Linh、Tran Yen Thi Hai、Kuno Akihiro、Muratani Masafumi、Kobayashi Shin、Nabekura Tsukasa、Shibuya Akira、Sugihara Eiji、Sato Taka-Aki、Fukuda Aya、Hayashi Yohei、Hisatake Koji
- Journal Title
  
  Stem Cell Reports
  
  Volume: 17 Issue: 1 Pages: 53-67
- DOI
  10.1016/j.stemcr.2021.11.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02678, KAKENHI-PROJECT-19H03203
[Journal Article] Utilization of a novel Sendai virus vector in ex vivo gene therapy for hemophilia A2021
- Author(s)
  Yamaki Yuni、Fukushima Takashi、Yoshida Naomi、Nishimura Ken、Fukuda Aya、Hisatake Koji、Aso Masayuki、Sakasai Tomoki、Kijima-Tanaka Junko、Miwa Yoshihiro、Nakanishi Mahito、Sumazaki Ryo、Takada Hidetoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 113 Issue: 4 Pages: 493-499
- DOI
  10.1007/s12185-020-03059-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04036, KAKENHI-PROJECT-19H03613, KAKENHI-PROJECT-21H02678
[Journal Article] Efficient Reprogramming of Canine Peripheral Blood Mononuclear Cells into Induced Pluripotent Stem Cells2021
- Author(s)
  Kimura Kazuto、Tsukamoto Masaya、Tanaka Miyuu、Kuwamura Mitsuru、Ohtaka Manami、Nishimura Ken、Nakanishi Mahito、Sugiura Kikuya、Hatoya Shingo
- Journal Title
  
  Stem Cells and Development
  
  Volume: 30 Issue: 2 Pages: 79-90
- DOI
  10.1089/scd.2020.0084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02349, KAKENHI-PROJECT-19H03203, KAKENHI-PROJECT-19J22851, KAKENHI-PROJECT-18K19273, KAKENHI-PROJECT-19K22945
[Journal Article] 4-Phenylbutyrate ameliorates apoptotic neural cell death in Down syndrome by reducing protein aggregates2020
- Author(s)
  Hirata Katsuya、Nambara Toshihiko、Kawatani Keiji、Nawa Nobutoshi、Yoshimatsu Hidetaka、Kusakabe Haruna、Banno Kimihiko、Nishimura Ken、Ohtaka Manami、Nakanishi Mahito、Taniguchi Hidetoshi、Arahori Hitomi、Wada Kazuko、Ozono Keiichi、Kitabatake Yasuji
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 14047-14047
- DOI
  10.1038/s41598-020-70362-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03619, KAKENHI-PROJECT-18K15709, KAKENHI-PROJECT-19H03203, KAKENHI-PROJECT-19K22945
[Journal Article] Functional analysis of PTH1R variants found in primary failure of eruption.2020
- Author(s)
  Izumida E, Suzawa T, Miyamoto Y, Yamada A, Takimoto R, Otsu M, Saito T, Yamaguchi T, Nishimura K, Ohtaka M, Nakanishi M, Yoshimura K, Sasa K, Takimoto R, Uyama R, Shirota T, Maki K, Kamijo R.
- Journal Title
  
  Journal of Dental Research
  
  Volume: 99 Issue: 4 Pages: 429-436
- DOI
  10.1177/0022034520901731
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09511, KAKENHI-PROJECT-19K18950, KAKENHI-PROJECT-17K11947, KAKENHI-PROJECT-20K21687, KAKENHI-PROJECT-19H03820, KAKENHI-PROJECT-18K09512, KAKENHI-PROJECT-18K09513, KAKENHI-PROJECT-18K09528, KAKENHI-PROJECT-18K09844, KAKENHI-PROJECT-19K19278, KAKENHI-PROJECT-19K24103, KAKENHI-PROJECT-19H03203, KAKENHI-PROJECT-19K22945
[Journal Article] Induction of Noonan syndrome-specific human-induced pluripotent stem cells under serum-, feeder-, and integration-free conditions2020
- Author(s)
  Atsuko Hamada, Eri Akagi, Fumitaka Obayashi, Sachiko Yamasaki, Koichi Koizumi, Manami Ohtaka, Ken Nishimura, Mahito Nakanishi, Shigeaki Toratani & Tetsuji Okamoto
- Journal Title
  
  In Vitro Cellular & Developmental Biology - Animal
  
  Volume: 56(10) Issue: 10 Pages: 888-895
- DOI
  10.1007/s11626-020-00515-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09723, KAKENHI-PROJECT-20K10117, KAKENHI-PROJECT-19K19198, KAKENHI-PROJECT-18H03000, KAKENHI-PROJECT-19H03203, KAKENHI-PROJECT-19K22945
[Journal Article] Template Activating Factor-I α Regulates Retroviral Silencing during Reprogramming2019
- Author(s)
  Bui Phuong Linh、Nishimura Ken、Seminario Mondejar Gonzalo、Kumar Arun、Aizawa Shiho、Murano Kensaku、Nagata Kyosuke、Hayashi Yohei、Fukuda Aya、Onuma Yasuko、Ito Yuzuru、Nakanishi Mahito、Hisatake Koji
- Journal Title
  
  Cell Reports
  
  Volume: 29 Issue: 7 Pages: 1909-1922
- DOI
  10.1016/j.celrep.2019.10.010
- NAID
  120007127699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04036, KAKENHI-PROJECT-19J11416, KAKENHI-PROJECT-17K08644, KAKENHI-PROJECT-19H03203, KAKENHI-PROJECT-17H05063
[Journal Article] Mechanisms of the Metabolic Shift during Somatic Cell Reprogramming2019
- Author(s)
  Nishimura Ken、Fukuda Aya、Hisatake Koji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 9 Pages: 2254-2254
- DOI
  10.3390/ijms20092254
- NAID
  120007133656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04036
[Journal Article] Non-invasive in vivo imaging of UCP1 expression in live mice via near-infrared fluorescent protein iRFP7202019
- Author(s)
  Fukuda Aya、Honda Shiho、Fujioka Norie、Sekiguchi Yuya、Mizuno Seiya、Miwa Yoshihiro、Sugiyama Fumihiro、Hayashi Yohei、Nishimura Ken、Hisatake Koji
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 11 Pages: 0225213-0225213
- DOI
  10.1371/journal.pone.0225213
- NAID
  120007132627
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04036, KAKENHI-PROJECT-17H05063
[Journal Article] Live-cell imaging of subcellular structures for quantitative evaluation of pluripotent stem cells2019
- Author(s)
  Nishimura Ken、Ishiwata Hiroshi、Sakuragi Yuta、Hayashi Yohei、Fukuda Aya、Hisatake Koji
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 1777-1777
- DOI
  10.1038/s41598-018-37779-x
- NAID
  120007128201
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04036, KAKENHI-PROJECT-16K07244, KAKENHI-PROJECT-17K19339
[Journal Article] Tcl1による代謝リプログラミングがiPS細胞誘導を促進する2018
- Author(s)
  西村健、久武幸司
- Journal Title
  
  医学のあゆみ
  
  Volume: 265 Pages: 293-294
- Data Source
  KAKENHI-PROJECT-16K07244
[Journal Article] Live cell imaging of X chromosome reactivation during somatic cell reprogramming2018
- Author(s)
  Tran Thi Hai Yen、Fukuda Aya、Aizawa Shiho、Bui Phuong Linh、Hayashi Yohei、Nishimura Ken、Hisatake Koji
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 15 Pages: 86-92
- DOI
  10.1016/j.bbrep.2018.07.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04036, KAKENHI-PROJECT-16K07244, KAKENHI-PROJECT-17K19339, KAKENHI-PROJECT-16K08610
[Journal Article] Tcl1による代謝リプログラミングがiPS細胞誘導を促進する2018
- Author(s)
  西村健、久武幸司
- Journal Title
  
  医学のあゆみ
  
  Volume: 265 Pages: 293-294
- Data Source
  KAKENHI-PROJECT-17K19339
[Journal Article] Tcl1による代謝リプログラミングがiPS細胞誘導を促進する2018
- Author(s)
  西村健、久武幸司
- Journal Title
  
  医学のあゆみ
  
  Volume: 265 Pages: 293-294
- Data Source
  KAKENHI-PROJECT-17H04036
[Journal Article] Time-course transcriptome analysis of human cellular reprogramming from multiple cell types reveals the drastic change occurs between the mid phase and the late phase2018
- Author(s)
  Kuno Akihiro、Nishimura Ken、Takahashi Satoru
- Journal Title
  
  BMC Genetics
  
  Volume: 19 Issue: 1 Pages: 9-9
- DOI
  10.1186/s12864-017-4389-8
- NAID
  120007134583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07244
[Journal Article] A role for KLF4 in promoting the metabolic shift via TCL1 during induced pluripotent stem cell generation.2017
- Author(s)
  Nishimura K, Aizawa S, Nugroho FL, Shiomitsu E, Tran YTH, Bui PL, Borisova E, Sakuragi Y, Takada H, Kurisaki A, Hayashi Y, Fukuda A, Nakanishi M, Hisatake K
- Journal Title
  
  Stem Cell Reports
  
  Volume: 8 Issue: 3 Pages: 787-801
- DOI
  10.1016/j.stemcr.2017.01.026
- NAID
  120007129229
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07244, KAKENHI-PROJECT-16K08610, KAKENHI-PROJECT-15K14986, KAKENHI-PROJECT-26290068
[Journal Article] Simple and effective generation of transgene-free induced pluripotent stem cells using an auto-erasable Sendai virus vector responding to microRNA-3022017
- Author(s)
  Nishimura Ken、Ohtaka Manami、Takada Hitomi、Kurisaki Akira、Tran Nhi Vo Kieu、Tran Yen Thi Hai、Hisatake Koji、Sano Masayuki、Nakanishi Mahito
- Journal Title
  
  Stem Cell Research
  
  Volume: 23 Pages: 13-19
- DOI
  10.1016/j.scr.2017.06.011
- NAID
  120007134806
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07244, KAKENHI-PROJECT-17K19339, KAKENHI-PROJECT-17H04036
[Journal Article] BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence2016
- Author(s)
  Hayashi Y, Hsiao EC, Sami S, Lancero M, Schlieve CR, Nguyen T, Yano K, Nagahashi A, Ikeya M, Matsumoto Y, Nishimura K, Fukuda A, Hisatake K, Tomoda K, Asaka I, Toguchida J, Conklin BR, Yamanaka S
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 113(46) Issue: 46 Pages: 13057-13062
- DOI
  10.1073/pnas.1603668113
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08610, KAKENHI-PROJECT-16H06662
[Journal Article] Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells2016
- Author(s)
  Matsumoto T, Fujimori K, Andoh-Noda T, Ando T, Kuzumaki N, Toyoshima M, Tada H, Imaizumi K, Ishikawa M, Yamaguchi R, Isoda M, Zhou Z, Sato S, Kobayashi T, Ohtaka M, Nishimura K, Kurosawa H, Yoshikawa T, Takahashi T, Nakanishi M, Ohyama M, Hattori N, Akamatsu W, Okano H.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 6 Issue: 3 Pages: 422-35
- DOI
  10.1016/j.stemcr.2016.01.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06780, KAKENHI-PROJECT-15K09849, KAKENHI-PROJECT-15K15041, KAKENHI-PROJECT-26830018, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-24116002, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-26870074, KAKENHI-ORGANIZER-24116001, KAKENHI-PROJECT-16K08280
[Journal Article] Genetic variability overrides the impact of parental cell-type and determines iPSCs differentiation potential2016
- Author(s)
  Kyttala A, Moraghebi R, Valensisi C, Kettunen J, Andrus C, Pasumarthy KK, Nakanishi M, Nishimura K, Ohtaka M, Weltner J, Handel BV, Parkkonen O, Sinisalo J, Jalanko A, Hawkins RD, Woods NB, Otonkoski T, Trokovic R
- Journal Title
  
  Stem Cell Reports
  
  Volume: 6 Issue: 2 Pages: 200-212
- DOI
  10.1016/j.stemcr.2015.12.009
- NAID
  120007129665
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870074
[Journal Article] The RNA-binding Complexes, NF45-NF90 and NF45-NF110, Associate Dynamically with the c-fos Gene and Function as Transcriptional Coactivators2015
- Author(s)
  Nakadai T, Fukuda A, Shimada M, Nishimura K, Hisatake K
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 290 Issue: 44 Pages: 26832-26845
- DOI
  10.1074/jbc.m115.688317
- NAID
  120007135696
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460354
[Journal Article] Generation of cleidocranial dysplasia-specific human induced pluripotent stem cells in completely serum-, feeder-, and integration-free culture.2015
- Author(s)
  Yamasaki S, Hamada A, Akagi E, Nakatao H, Ohtaka M, Nishimura K, Nakanishi M, Toratani S, Okamoto T.
- Journal Title
  
  In Vitro Cell Dev Biol Anim.
  
  Volume: 52 Issue: 2 Pages: 252-264
- DOI
  10.1007/s11626-015-9968-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11251, KAKENHI-PROJECT-15H05043, KAKENHI-PROJECT-26670865, KAKENHI-PROJECT-26861723, KAKENHI-PROJECT-26870074, KAKENHI-PROJECT-15H06435, KAKENHI-PROJECT-16K15823, KAKENHI-PROJECT-16K20580
[Journal Article] An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils.2015
- Author(s)
  Lin HT, Masaki H, Yamaguchi T, Wada T, Yachie A, Nishimura K, Ohtaka M, Nakanishi M, Nakauchi H, Otsu M.
- Journal Title
  
  Mol Ther Methods Clin Dev
  
  Volume: 2 Pages: 15046-15046
- DOI
  10.1038/mtm.2015.46
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09642, KAKENHI-PROJECT-26460358, KAKENHI-PROJECT-26870074
[Journal Article] A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy.2015
- Author(s)
  Ando M, Nishimura T, Yamazaki S, Yamaguchi T, Kawana-Tachikawa A, Hayama T, Nakauchi Y, Ando J, Ota Y, Takahashi S, Nishimura K, Ohtaka M, Nakanishi M, Miles JJ, Burrows SR, Brenner MK, Nakauchi H.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 5(4) Issue: 4 Pages: 597-608
- DOI
  10.1016/j.stemcr.2015.07.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460358, KAKENHI-PROJECT-15J40133, KAKENHI-PROJECT-25460354, KAKENHI-PROJECT-26870074, KAKENHI-PROJECT-25293226, KAKENHI-PROJECT-25713037
[Journal Article] Interspecific in vitro assay for the chimera-forming ability of human pluripotent stem cells.2015
- Author(s)
  Masaki H, Kato-Itoh M, Umino A, Sato H, Hamanaka S, Kobayashi T, Yamaguchi T, Nishimura K, Ohtaka M, Nakanishi M, Nakauchi H.
- Journal Title
  
  Development.
  
  Volume: 142(18) Pages: 3222-30
- DOI
  10.1242/dev.124016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460358, KAKENHI-PROJECT-15K20948, KAKENHI-PROJECT-25460354, KAKENHI-PROJECT-26870074
[Journal Article] Klf4遺伝子発現調節によるiPS細胞誘導中間体の作製2015
- Author(s)
  西村健、久武幸司
- Journal Title
  
  医学のあゆみ
  
  Volume: 255 Pages: 173-174
- Data Source
  KAKENHI-PROJECT-26870074
[Journal Article] Advanced Feeder-Free Generation of iPSC Directly From Blood Cells2014
- Author(s)
  Trokovic R, Weltner J, Nishimura K, Ohtaka M, Nakanishi M, Salomaa V, Jalanko A, Otonkoski T, A Kyttälä
- Journal Title
  
  Stem Cells Trans. Med.
  
  Volume: 3 Issue: 12 Pages: 1402-1409
- DOI
  10.5966/sctm.2014-0113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460354, KAKENHI-PROJECT-26870074
[Journal Article] Prediction of inter-individual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes2014
- Author(s)
  Takayama K, Morisaki Y, Kuno S, Nagamoto Y, Harada K, Furukawa N, Ohtaka M, Nishimura K, Imagawa K, Sakurai F, Tachibana M, Sumazaki R, Noguchi E, Nakanishi M, Hirata K, Kawabata K, Mizuguchi H
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 111 Pages: 16772-16777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460354
[Journal Article] Prediction of inter-individual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes.2014
- Author(s)
  Takayama K., Morisaki Y., Kuno S., Nagamoto Y., Harada K., Furukawa N., Ohtaka M.,Nishimura K., Imagawa K., Sakurai F., Tachibana M., Sumazaki R., Noguchi E., Nakanishi M., Hirata K., Kawabata K., Mizuguchi H.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 111 Issue: 47 Pages: 16772-7
- DOI
  10.1073/pnas.1413481111
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J00448, KAKENHI-PROJECT-26870074
[Journal Article] Manipulation of KLF4 expression generates iPSCs paused at successive stages of reprogramming2014
- Author(s)
  K. Nishimura, T. Kato, C. Chen, L. Oinam, E. Shiomitsu, D. Ayakawa, M. Ohtaka, A. Fukuda, M. Nakanishi, K. Hisatake
- Journal Title
  
  Stem Cell Reports
  
  Volume: 3 Issue: 5 Pages: 915-929
- DOI
  10.1016/j.stemcr.2014.08.014
- NAID
  120007136516
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870074
[Journal Article] Manipulation of KLF4 Expression Generates iPSCs Paused at Successive Stages of Reprogramming2014
- Author(s)
  Nishimura K, Kato T, Chen C, Oinam L, Shiomitsu E, Ayakawa D, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K
- Journal Title
  
  Stem Cell Reports
  
  Volume: 3 Pages: 915-929
- NAID
  120007136516
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460354
[Journal Article] Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation2013
- Author(s)
  T. Nishimura, S. Kaneko, A. Kawana-Tachikawa, Y. Tajima, H. Goto, D. Zhu, K. Nakayama-Hosoya, S. Iriguchi, Y. Uemura, T. Shimizu, N. Takayama, D. Yamada, K. Nishimura, M. Ohtaka, N. Watanabe, S. Takahashi, A. Iwamoto, H. Koseki, M. Nakanishi, K. Eto, H. Nakauchi
- Journal Title
  
  Cell Stem Cells
  
  Volume: Vol. 12 Pages: 114-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700474
[Journal Article] Heterogeneous Nuclear Ribonucleoprotein R Cooperates with Mediator to Facilitate Transcription Reinitiation on the c-Fos Gene2013
- Author(s)
  A. Fukuda, M. Shimada, T. Nakadai, K. Nishimura, K. Hisatake
- Journal Title
  
  PLOS ONE
  
  Volume: Vol. 8 Issue: 8 Pages: e72496-e72496
- DOI
  10.1371/journal.pone.0072496
- NAID
  120007136844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700474, KAKENHI-PROJECT-25460354
[Journal Article] Podocalyxin is a Glycoprotein Ligand of the Human Pluripotent Stem Cell-Specific Probe rBC2LCN2013
- Author(s)
  H. Tateno, A. Matsushima, K. Hiemori, Y. Onuma, Y. Ito, K. Hasehira, K. Nishimura, M. Ohtaka, S. Takayasu, M. Nakanishi, Y. Ikehara, M. Nakanishi, K. Ohnuma, T. Chan, M. Toyoda, H. Akutsu, A. Umezawa, M. Asashima, J. Hirabayashi
- Journal Title
  
  Stem Cells Trans. Med.
  
  Volume: Vol. 2 Pages: 265-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700474
[Journal Article] Expansion of Functional Human Mucosal-Associated Invariant T Cells via Reprogramming to Pluripotency and Redifferentiation2013
- Author(s)
  H. Wakao, K. Yoshikiyo, U. Koshimizu, T. Furukawa, K. Enomoto, T. Matsunaga, T. Tanaka, Y. Yasutomi, T. Yamada, H. Minakami, J. Tanaka, A. Oda, T. Sasaki, R. Wakao, O. Lantz, T. Udagawa, Y. Sekiya, K. Higuchi, N. Harada, K. Nishimura, M. Ohtaka, M. Nakanishi, H. Fujita
- Journal Title
  
  Cell Stem Cells
  
  Volume: Vol. 12 Pages: 546-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700474
[Journal Article] GPAT2, a mitochondrial outer membrane protein, in piRNA biogenesis in germline stem cells2013
- Author(s)
  Y. Shiromoto, S. Kuramochi-Miyagawa, A. Daiba, S. Chuma, A. Katanaya, A. Katsumata, K. Nishimura, M. Ohtaka, M. Nakanishi, T. Nakamura, K. Yoshinaga, N. Asada, S. Nakamura, T. Yasunaga, K. Kojima-Kita, D. Itou, T. Kimura, T. Nakano
- Journal Title
  
  RNA
  
  Volume: Vol. 19 Pages: 803-810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] Dual function of E2F4 on iPSC generation2022
- Author(s)
  Nishimura Ken、Kishimoto Takumi、Hisatake Koji
- Organizer
  TGSW2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02678
[Presentation] リプログラム因子のパイオニア因子としての機能と量依存性2022
- Author(s)
  西村健、久野朗広、久武幸司
- Organizer
  第21回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] A dCas9 based method can identify novel regulators of Nanog and pluripotency2022
- Author(s)
  Nishimura Ken、Arun Burramsett、Hisatake Koji
- Organizer
  ISSCR2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02678
[Presentation] iPS細胞誘導過程において二相性の機能を有するE2F4の解析2022
- Author(s)
  西村健、岸本拓実、久武幸司
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02678
[Presentation] Mechanistic analysis of pluripotency acquisition by using paused iPSCs2021
- Author(s)
  Hamzah M, Nishimura K, Hisatake K
- Organizer
  Tsukuba Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] Interleukin Enhancer Binding Factors 2 and 3 inhibit retrovirus expression2021
- Author(s)
  Gonzalo SB, Bui PL, Nishimura K, Hisatake K
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] Downregulation of Odd-Skipped Related 2, a Novel Regulator of Epithelial-Mesenchymal Transition, Enables Efficient Somatic Cell Reprogramming2021
- Author(s)
  Nishimura K, Anh LPH, Linh NT, Kato T, Hisatake K
- Organizer
  ISSCR2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02678
[Presentation] Downregulation of Odd-Skipped Related 2, a Novel Regulator of Epithelial-Mesenchymal Transition, Enables Efficient Somatic Cell Reprogramming2021
- Author(s)
  Nishimura K, Anh LPH, Linh NT, Kato T, Hisatake K
- Organizer
  ISSCR2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] Interleukin Enhancer Binding Factors 2 and 3 inhibit retrovirus expression2021
- Author(s)
  Gonzalo SB, Bui PL, Nishimura K, Hisatake K
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02678
[Presentation] Paused iPS細胞を用いたKLF4量依存的エピジェネティクス制御機構の解析2021
- Author(s)
  西村健、Arun Kumar、岸本拓実、久武幸司
- Organizer
  第14回エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] Application of iPS cells to regenerative medicine using novel gene transfer system2021
- Author(s)
  Ken Nishimura
- Organizer
  International Conference and Workshop on Global Trends in Health and Life Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] Interleukin Enhancer Binding Factors 2 and 3 inhibit retrovirus expression2021
- Author(s)
  Gonzalo SB, Nishimura K, Hisatake K
- Organizer
  Tsukuba Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02678
[Presentation] Mechanistic analysis of pluripotency acquisition by using paused iPSCs2021
- Author(s)
  Hamzah M, Nishimura K, Hisatake K
- Organizer
  Tsukuba Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02678
[Presentation] iPS細胞誘導におけるX染色体再活性化機構の解明2021
- Author(s)
  相澤志穂、西村健、久武幸司
- Organizer
  第20回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] Interleukin Enhancer Binding Factors 2 and 3 inhibit retrovirus expression2021
- Author(s)
  Gonzalo SB, Nishimura K, Hisatake K
- Organizer
  Tsukuba Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] Reactivation of X chromosome might start from the identical region during mouse iPSC generation2020
- Author(s)
  Aizawa S, Bui PL, Nishimura K, Hisatake K
- Organizer
  ISSCR2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] Analysis of KLF4 dose dependent iPSC generation in early stage of reprogramming2020
- Author(s)
  Yamanaka T, Nishimura K, Hisatake K
- Organizer
  TGSW2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] 再生医療や創薬研究を支援する高純度分化細胞選択法2020
- Author(s)
  西村健
- Organizer
  BioJapan2020
- Data Source
  KAKENHI-PROJECT-19K22945
[Presentation] PD imaging systemを用いて生きたまま幹細胞の多能性を定量的に解析する2019
- Author(s)
  西村健、石渡裕、久武幸司
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] Dose dependent transcriptional regulation of KLF42019
- Author(s)
  Arun B Kumar, Ken Nishimura, Koji Hisatake
- Organizer
  Tsukuba Conference 2019
- Data Source
  KAKENHI-PROJECT-17H04036
[Presentation] 安全な再生医療を実現させる高純度分化細胞選択法2019
- Author(s)
  西村健
- Organizer
  日中大学フェア＆フォーラム in CHINA 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22945
[Presentation] Dose dependent transcriptional regulation of KLF42019
- Author(s)
  Kumar BA, Nishimura K, Hisatake K
- Organizer
  TC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03203
[Presentation] PD imaging systemを用いて生きたまま幹細胞の多能性を定量的に解析する2019
- Author(s)
  西村健、石渡裕、久武幸司
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04036
[Presentation] KLF4-dose dependent metabolic shift through TCL1 during iPSC generation2018
- Author(s)
  Nishimura K, Kumar BA, Hayashi Y, Fukuda A, Hisatake K
- Organizer
  ISSCR2018
- Data Source
  KAKENHI-PROJECT-17H04036
[Presentation] Functional analysis of SOX9 variants in chondrocyte differentiation2018
- Author(s)
  Sekiguchi Y, Fukuda A, Nishimura K, Hisatake K
- Organizer
  Tsukuba Global Science Week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08610
[Presentation] KLF4-dose dependent metabolic shift through TCL1 during iPSC generation2018
- Author(s)
  Nishimura K, Kumar BA, Hayashi Y, Fukuda A, Hisatake K
- Organizer
  ISSCR2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07244
[Presentation] Analysis on transcriptional regulation in the early phase of somatic cell reprogramming2018
- Author(s)
  Le PHA, Kato T, Nguyen TL, Fukuda A, Nishimura K, Hisatake K
- Organizer
  Tsukuba Global Science Week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08610
[Presentation] Quantitative Assessment of Pluripotent Stem Cells by an Improved RM-DIC Imaging System2018
- Author(s)
  Nishimura K, Ishiwata H, Sakuragi Y, Hayashi Y, Fukuda A, Hisatake K
- Organizer
  2018 TERMIS World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07244
[Presentation] Functional analysis of unsaturated fatty acids in brown adipocytes2018
- Author(s)
  Hirai R, Takei Y, Shimodaira Y, Kano H, Shimada R, Nishimura K, Fukuda A, Hisatake K
- Organizer
  Tsukuba Global Science Week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08610
[Presentation] KLF4-dose dependent metabolic shift through TCL1 during iPSC generation2018
- Author(s)
  Nishimura K, Kumar BA, Hayashi Y, Fukuda A, Hisatake K
- Organizer
  ISSCR2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19339
[Presentation] 褐色脂肪細胞における不飽和脂肪酸の機能解析2018
- Author(s)
  平井理愛、武井祐樹、下平雄貴、加納英明、島田林太郎、西村健、福田綾、久武幸司
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08610
[Presentation] X染色体の再活性化をモデルとしたエピジェネティクス転写制御機構の解明2018
- Author(s)
  相澤志穂、Bui PL、西村健、久武幸司
- Organizer
  超異分野学会2018
- Data Source
  KAKENHI-PROJECT-16K07244
[Presentation] Mechanistic analysis of the initiation of retroviral gene silencing by reprogramming factors2018
- Author(s)
  Bui PL、Nishimura K、Hisatake K
- Organizer
  The Exploring identity: lessons from genomes and epigenomes meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07244
[Presentation] 軟骨分化におけるSOX9変異体の機能解析2018
- Author(s)
  関口裕也、福田綾、西村健、久武幸司
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08610
[Presentation] iPS細胞誘導機構解明のためのX染色体再活性化状態定量システムの開発2017
- Author(s)
  相澤志穂、Bui PL、西村健、久武幸司
- Organizer
  第16回日本再生医療学会
- Place of Presentation
  仙台国際センター・宮城県・仙台市
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-16K07244
[Presentation] Mechanistic analysis of the initiation of retroviral gene silencing by reprogramming factors2017
- Author(s)
  Bui PL, Nishimura K, Hisatake K
- Organizer
  The 6th Human Biology Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07244
[Presentation] "Mechanistic analysis of the initiation of retroviral gene silencing by reprogramming factors2017
- Author(s)
  Bui PL, Nishimura K, Hisatake K
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04036
[Presentation] Mechanistic analysis of the initiation of retroviral gene silencing by reprogramming factors2017
- Author(s)
  Bui PL., Nishimura K., Hisatake K
- Organizer
  Tsukuba Global Science Week 2017
- Data Source
  KAKENHI-PROJECT-17H04036
[Presentation] iPS細胞誘導におけるX染色体再活性化機構の解析2017
- Author(s)
  相澤志穂、Bui PL、西村健、久武幸司
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04036
[Presentation] iPS細胞誘導におけるX染色体再活性化機構の解析2017
- Author(s)
  相澤志穂、Bui PL、西村健、久武幸司
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16K07244
[Presentation] UCP1発現脂肪細胞の非侵襲イメージング法の作製2017
- Author(s)
  本多志帆、福田綾、水野聖哉、杉山文博、岡松優子、斉藤昌之、林洋平、西村健、久武幸司
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08610
[Presentation] Tcl1による代謝リプログラミングはiPS細胞の多能性を向上させる2017
- Author(s)
  西村健、相澤志穂、櫻木佑太、林洋平、福田綾、久武幸司
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K19339
[Presentation] iPS細胞誘導におけるX染色体再活性化を定量化する方法の開発2016
- Author(s)
  相澤志穂、Bui PL、西村健、久武幸司
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜・神奈川県・横浜市
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-16K07244
[Presentation] A quantitative method for analysis of X chromosome reactivation in iPSC production2016
- Author(s)
  Aizawa S, Bui PL, Nishimura K, Hisatake K
- Organizer
  The 5th Human Biology Symposium
- Place of Presentation
  つくば国際会議場・茨城県・つくば市
- Year and Date
  2016-09-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07244
[Presentation] Molecular mechanism of KLF4-dose dependent induction of pluripotency during iPSC production2016
- Author(s)
  Nishimura K, Liliani NF, Shiomitsu E, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K
- Organizer
  CiRA/ISSCR International Symposium
- Place of Presentation
  京都大学 iPS 細胞研究所 (CiRA)
- Year and Date
  2016-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] Molecular mechanism of KLF4-dose dependent induction of pluripotency during iPSC production2016
- Author(s)
  K. Nishimura, N.F. Liliani, E. Shiomitsu, M. Ohtaka, A. Fukuda, M. Nakanishi, K. Hisatake
- Organizer
  CiRA/ISSCR International Symposium
- Place of Presentation
  京都大学百周年時計台記念館
- Year and Date
  2016-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870074
[Presentation] iPS細胞の多能性評価に向けた非線形分光イメージング2016
- Author(s)
  米山弘亮、瀬川尋貴、西村健、福田綾、久武幸司、加納英明
- Organizer
  応用物理学会春季学術講演会
- Place of Presentation
  東京工業大学（東京都目黒区）
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-26560200
[Presentation] Application of novel RNA vector to stem cell engineering2015
- Author(s)
  Ken Nishimura
- Organizer
  Gene-editing, transgenics & stem cells: Frontiers in medical and molecular therapeutics Workshop
- Place of Presentation
  Dublin, Ireland
- Year and Date
  2015-09-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870074
[Presentation] Paused iPSCを用いたiPS細胞誘導過程の解析2015
- Author(s)
  西村　健
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26870074
[Presentation] 非線形マルチモーダル顕微鏡を用いたiPS細胞のリプログラミング過程のin vivo追跡2015
- Author(s)
  米山弘亮,瀬川尋貴,西村健,福田綾,久武幸司,加納英明
- Organizer
  分子科学討論会
- Place of Presentation
  東京工業大学（東京都目黒区）
- Year and Date
  2015-09-16
- Data Source
  KAKENHI-PROJECT-26560200
[Presentation] Manipulation of KLF4 expression reveals a mechanistic insight into an intermediate state of reprogramming2015
- Author(s)
  Hisatake K, Lilliani NF, Shiomitsu E, Ohtaka M, Fukuda A, Nakanishi M, Nishimura K
- Organizer
  第38回分子生物学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] Manipulation of KLF4 expression generates iPSCs paused at successive stages of reprogramming2015
- Author(s)
  Nishimura K, Shiomitsu E, Liliani N.F., Kato T, Chen C, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K
- Organizer
  International Society of Stem Cell Research 13th Annual Meeting
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] CARS Molecular Fingerprinting of iPS Cells-Toward Visualizing Pluripotency2015
- Author(s)
  Hiroaki Yoneyama,Hiroki Segawa,Ken Nishimura,Aya Fukuda,Koji Hisatake,Hideaki Kano
- Organizer
  ICAVS8 (8th International Conference on Advanced Vibrational spectroscopy
- Place of Presentation
  ウィーン工科大学（ウィーン）, オーストリア
- Year and Date
  2015-07-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26560200
[Presentation] Nonlinear Multimodal spectral Imaging of Living Cells2015
- Author(s)
  Hiroaki Yoneyama, Hiroki segawa, Ken Nishimura, Aya Fukuda, Koji Hisatake, and Hideaki Kano
- Organizer
  The Third Taiwan International symposium on Raman Spectroscopy & TARS Summer School
- Place of Presentation
  Sun Moon Lake(Nantou), Taiwan
- Year and Date
  2015-06-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26560200
[Presentation] Manipulation of KLF4 expression generates iPSCs paused at successive stages of reprogramming2015
- Author(s)
  K. Nishimura, E. Shiomitsu, N.F. Liliani, T. Kato, C. Chen, M. Ohtaka, A. Fukuda, M. Nakanishi, K. Hisatake
- Organizer
  International Society of Stem Cell Research 13th Annual Meeting
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870074
[Presentation] Klf4遺伝子発現量調節による多能性が異なるiPS細胞の誘導2014
- Author(s)
  西村　健
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26870074
[Presentation] iPS細胞発現誘導初期における体細胞特異的遺伝子の発現減少と誘導効率への影響2014
- Author(s)
  加藤哲男、Lalhaba Oinam、塩満鋭美、福田綾、中西真人、西村健、久武幸司
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都、国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] CARS分光イメージング法によるiPS細胞の非染色・非標識イメージング2014
- Author(s)
  米山弘亮、瀬川尋貴、西村健、福田綾、久武幸司、加納英明
- Organizer
  分子科学討論会
- Place of Presentation
  広島大学（東広島市）
- Year and Date
  2014-09-24
- Data Source
  KAKENHI-PROJECT-26560200
[Presentation] iPS細胞の多能性可視化に向けたCARS分光イメージング法の開発2014
- Author(s)
  米山弘亮、瀬川尋貴、西村健、福田綾、久武幸司、加納英明
- Organizer
  分光学会年次講演会
- Place of Presentation
  理化学研究所（和光市）
- Year and Date
  2014-05-26
- Data Source
  KAKENHI-PROJECT-26560200
[Presentation] 初期化が途中で停止した細胞を用いたiPS細胞誘導過程の解析2014
- Author(s)
  西村健
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都国際会議場、京都
- Year and Date
  2014-03-05
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] 初期化が途中で停止した細胞を用いたiPS細胞誘導過程の解析2014
- Author(s)
  西村健、加藤哲男、Lalhaba Oinam、塩満鋭美、成田孝仁、大高真奈美、福田綾、中西真人、久武幸司
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都、国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] Manipulation of Klf4 expression produces paused iPSC stalling at distinct intermediate stages of reprogramming2014
- Author(s)
  西村　健
- Organizer
  Keystone Symposia “Stem Cells and Reprogramming”
- Place of Presentation
  Olympic Valley, USA
- Year and Date
  2014-04-08
- Data Source
  KAKENHI-PROJECT-26870074
[Presentation] Klf4遺伝子発現量による初期化が途中で停止した細胞の誘導2013
- Author(s)
  西村健、加藤哲男、Oinam Lalhaba、塩満鋭美、成田孝仁、大高真奈美、福田綾、中西真人、久武幸司
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸、神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] iPS細胞誘導初期におけるメカニズム解析2013
- Author(s)
  加藤哲男、西村健、塩満鋭美、綾川大介、福田綾、久武幸司
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸、神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] Taking snap shots during iPSC production by SeVdp vectors2013
- Author(s)
  K. Nishimura
- Organizer
  International Society of Stem Cell Research 11^<th> Annual Meeting
- Place of Presentation
  The Boston Convention Center、Boston、USA
- Year and Date
  2013-06-14
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] Taking snap shots during iPSC production by SeVdp vectors2013
- Author(s)
  Nishimura K, Kato T, Oinam L, Narita T, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.
- Organizer
  International Society of Stem Cell Research 11th Annual Meeting
- Place of Presentation
  米国、ボストン、Boston Convention & Exhibition Center
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] Manipulation of Klf4 expression produces snap shots of iPSC induction2013
- Author(s)
  Nishimura K, Kato T, Oinam L, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.
- Organizer
  CSHAsia 2013 Conference on CSHA/ISSCR Joint Meeting on Stem Cells in Science and Medicine
- Place of Presentation
  中国、江蘇省、江蘇国際会議センター
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] Manipulation of Klf4 expression produces snap shots of iPSC induction2013
- Author(s)
  K. Nishimura
- Organizer
  CSHA/ISSCR Joint Meeting on Stem Cells in Science and Medicine
- Place of Presentation
  Suzhou Dushu Lake Conference Center、Suzhou、China
- Year and Date
  2013-10-16
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] Klf4遺伝子発現量調節による初期化が途中で停止した細胞の誘導2013
- Author(s)
  西村健
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場、神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] SeVdpベクターを用いたiPS細胞の品質調節メカニズムの解析2013
- Author(s)
  西村健
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] Analysis of the Partially Reprogrammed iPS Cells2013
- Author(s)
  Shiomitsu E, Nishimura K, Kato T, Oinam L, Fukuda A, Hisatake K
- Organizer
  The 12th NTU-Japan International Student Mini-Symposium on Life Science
- Place of Presentation
  台湾、台北、国立台湾大学
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] Application of Cytoplasmic RNA vector Developed from Noncytopathic RNA Viruses to Stem Cell Engineering2013
- Author(s)
  K. Nishimura
- Organizer
  The 2nd Meeting on RNA and Biofunctions-Asia Study
- Place of Presentation
  ホテルレオパレス福岡、福岡
- Year and Date
  2013-01-09
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] Regulated Induction of Partially Reprogrammed iPS Cells by SeVdp Vectors2013
- Author(s)
  Hisatake K, Kato T, Oinam L, Narita T, Ohtaka M, Fukuda A, Nakanishi M, Nishimura K.
- Organizer
  Cold Spring Harbor Laboratory meeting on Stem Cell Biology
- Place of Presentation
  米国、ニューヨーク、Cold Spring Harbor Laboratory
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] QUALITY CONTROL OF IPS CELLS BY UNIQUE GENE TRANSFER SYSTEM2012
- Author(s)
  K. Nishimura
- Organizer
  International Society of Stem Cell Research 10^<th> Annual Meeting
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2012-06-14
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] RNA工学とウイルス学の融合による簡便かつ高効率なiPS細胞樹立方法の確立2011
- Author(s)
  西村健
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-23890026
[Presentation] SeVdpベクターを用いたiPS細胞の品質調節メカニズムの解析
- Author(s)
  西村健、成田孝仁、大高真奈美、高安聡子、佐野将之、福田綾、中西真人、久武幸司
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] iPS細胞誘導初期におけるメカニズム解析
- Author(s)
  加藤哲男、西村健、塩満鋭美、綾川大介、福田綾、久武幸司
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] Paused iPSCを用いたiPS細胞誘導過程の解析
- Author(s)
  西村健、加藤哲男、陳晨、Lalhaba Oinam、塩満鋭美、大高真奈美、福田綾、中西真人、久武幸司
- Organizer
  第14回日本再生医療学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] QUALITY CONTROL OF IPS CELLS BY UNIQUE GENE TRANSFER SYSTEM
- Author(s)
  K. Nishimura, M. Ohtaka, S. Takayasu, M. Sano, K. Hisatake, M. Nakanishi
- Organizer
  International Society of Stem Cell Research 10th Annual Meeting
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] Klf4遺伝子発現量調節による初期化が途中で停止した細胞の誘導
- Author(s)
  西村健、加藤哲男、Oinam Lalhaba、塩満鋭美、成田孝仁、大高真奈美、福田綾、中西真人、久武幸司
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] Manipulation of Klf4 expression produces snap shots of iPSC induction
- Author(s)
  K. Nishimura, T. Kato, L. Oinam, T. Narita, M. Ohtaka, A. Fukuda, M. Nakanishi, K. Hisatake
- Organizer
  CSHA/ISSCR Joint Meeting on Stem Cells in Science and Medicine
- Place of Presentation
  蘇州、中国
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] 初期化が途中で停止した細胞を用いたiPS細胞誘導過程の解析
- Author(s)
  西村健、加藤哲男、Oinam Lalhaba、塩満鋭美、成田孝仁、大高真奈美、福田綾、中西真人、久武幸司
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] Taking snap shots during iPSC production by SeVdp vectors
- Author(s)
  K. Nishimura, T. Kato, L. Oinam, T. Narita, M. Ohtaka, A. Fukuda, M. Nakanishi, K. Hisatake
- Organizer
  International Society of Stem Cell Research 11th Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] iPS細胞誘導初期に関与する転写因子の同定とその機能解析
- Author(s)
  加藤哲男、西村健、Nguyen Thuy Linh、大高真奈美、福田綾、中西真人、久武幸司
- Organizer
  第14回日本再生医療学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] iPS細胞誘導初期における体細胞特異的転写因子の発現減少と誘導効率への影響
- Author(s)
  加藤哲男、西村健、塩満鋭美、綾川大介、福田綾、久武幸司
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] Application of CYtoplasmic RNA vector Developed from Noncytopathic RNA Viruses to Stem Cell Engineering
- Author(s)
  K. Nishimura
- Organizer
  The 2nd Meeting on RNA and Biofunctions-Asia Study
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24700474
[Presentation] 細胞の初期化におけるリプログラム因子の機能解析
- Author(s)
  塩満鋭美、西村健、Lalhaba Oinam、Fransiska Liliani、福田綾、久武幸司
- Organizer
  第14回日本再生医療学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] Klf4遺伝子発現量調節による多能性が異なるiPS細胞の誘導
- Author(s)
  西村健、加藤哲男、C. Chen、L. Oinam、塩満鋭美、大高真奈美、福田綾、中西真人、久武幸司
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25460354
[Presentation] Regulated induction of partially reprogrammed iPS cells by SeVdp vectors
- Author(s)
  K. Hisatake, T. Kato, L. Oinam, T. Narita, M. Ohtaka, A. Fukuda, M. Nakanishi, K. Nishimura
- Organizer
  Cold Spring Harbor Laboratory Meeting on Stem Cell Biology
- Place of Presentation
  Long Island, USA
- Data Source
  KAKENHI-PROJECT-24700474

1. Hisatake Koji (70271236)

# of Collaborated Projects: 5 results

# of Collaborated Products: 44 results
2. Fukuda Aya (50436276)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
3. 林洋平 (90780130)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. 久野朗広 (60830122)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. KANO Hideaki (70334240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. Tsuchiya Atsunori (70464005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 佐野将之 (80415687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KITABATAKE Yasuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. ITOH Tohru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. WADA Taizo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. YAMAGUCHI Tomoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. SUZAWA Tetsuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. HATOYA Shingo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. YAMASAKI Sachiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 虎谷茂昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 岡本哲治

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 佐藤栄人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 上條竜太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 杉浦喜久弥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 濱田充子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishimura Ken 西村 健

NISHIMURA Ken 西村 健

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Cell fate decision by dose of transcription factorsPrincipal Investigator

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Safe and efficient selection of differentiated cells by stage-specific gene expression from auto-erasable vectorPrincipal Investigator

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Molecular dynamics of epigenomic transcriptional regulation by Klf4 in iPSC generationPrincipal Investigator

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Spatially and time-dependent analysis of initial phase of epigenetic regulation in X chromosome reactivationPrincipal Investigator

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Mechanistic analysis of iPSC production using paused iPSCPrincipal Investigator

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Establishment of safe and efficient differentiation system using automatic removal vectorPrincipal Investigator

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Nishimura Ken 西村健

NISHIMURA Ken 西村健