Kawai Kazushige 川合一茂

… Alternative Names

KAWAI Kazushige 川合一茂

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Researcher Number	80571942
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 届出研究員 2025: 地方独立行政法人東京都立病院機構東京都立駒込病院(臨床研究室), 大腸外科, 部長
Affiliation (based on the past Project Information) *help	2023: 東京大学, 医学部附属病院, 准教授 2022 – 2023: 東京大学, 医学部附属病院, 届出研究員 2020 – 2021: 東京大学, 医学部附属病院, 准教授 2015 – 2019: 東京大学, 医学部附属病院, 講師 2012 – 2014: 東京大学, 医学部附属病院, 助教 2013: 東京大学, 医学部付属病院, 助教
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 50010:Tumor biology-related / Tumor therapeutics / Tumor diagnostics / Tumor diagnosis
Keywords	Principal Investigator 放射線療法 / 大腸癌 / 直腸癌 / 化学放射線療法 / SN-38 / 放射線 / Chloroquine / Temsirolimus / 上皮間葉転換 / CPT-11 / HIF-1α … More Except Principal Investigator … More 大腸癌 / アポトーシス / 血管新生 / 大腸がん / 腫瘍免疫 / 放射線治療 / インドールアミン酸素添加酵素 / メタボローム解析 / インドールアミン-2,3-ジオキシゲナーゼ / メタボローム / 放射線照射 / 転移 / 1-methyl-tryptophan / インドールアミン酸素添加酵素 / perineural invasion / 閉塞 / 神経栄養因子 / 神経侵襲 / 神経周囲侵襲 / HIF-1α / TAS-102 / 放射線療法 / Trifluridine / ＮＧＳ / 癌予測モデル / ミトコンドリアＤＮＡ / 潰瘍性大腸癌関連大腸癌 / ミトコンドリア / 潰瘍性大腸炎 / 潰瘍性大腸炎関連大腸癌 / ミトコンドリアDNA / パクリタキセル / 腹膜播種マウスモデル / ドラッグデリバリーシステム / 腹腔内化学療法 / ドラッグデリバリー / 腹膜播種 / 低酸素活性化プロドラッグ / 細胞周期 / 低酸素プロドラッグ / mTOR阻害剤 / 質量分析法 / リン脂質性メディエーター / DDHD1 / GPR55 / リゾホスファチジルイノシトール / リゾリン脂質 / 癌 / integrin / hypoxia / CD133 / 上皮間葉転換 / 外科 / 一塩基多型 / 回腸嚢炎 / Jagged-1 / γセクレターゼ阻害 / Notch / ガンマセクレターゼ阻害剤 / ガンマセクレターゼ / ケミカルバイオロジー / 抗がん物質探索 / colon26 / 抗癌作用 / 血管内皮前駆細胞 / オートファジー / スルフォラファン / 免疫染色 / リンチ様大腸腫瘍 / MLH1遺伝子メチル化 / リンチ症候群 / マイクロサテライト不安定性 / autophagy / 低栄養 / 低酸素 / 腫瘍マーカー / LINE1 / 血中遊離DNA / バイオマーカー Less

直腸癌化学放射線療法における遺伝子変異タイプと放射線耐性機構の活性化の相関の解明Principal Investigator
- Principal Investigator
  
  川合一茂
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  The University of Tokyo
Multilayer analyses on anti-tumot activities of IDO1 blockade and raidation therapy
- Principal Investigator
  
  Nozawa Hiroaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo
Development of chemoradiotherapy using TAS-102 for rectal cancer
- Principal Investigator
  
  Nishikawa Takeshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Research Institute for Clinical Oncology Saitama Cancer Center
Molecular mechanisms for factors associated with perineural invasion as a prognostic factor in colorectal cancer
- Principal Investigator
  
  Nozawa Hiroaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  The University of Tokyo
mTOR inhibitor in combination with hypoxia-activated prodrugs for the treatment of patients with colorectal cancer
- Principal Investigator
  
  Kaneko Manabu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  The University of Tokyo
Drug delivery system in intraperitoneal chemotherapy for peritoneal dissemination of colorectal cancer
- Principal Investigator
  
  Emoto Shigenobu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  The University of Tokyo
ミトコンドリアDNAによる潰瘍性大腸炎関連癌の早期発見マーカーの開発
- Principal Investigator
  
  田中敏明
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  The University of Tokyo
Search and functional elucidation of novel colorectal cancer-specific phospholipid mediators using LC-MS / MS
- Principal Investigator
  
  SONODA HIROFUMI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
Epithelial Mesenchymal Transition of rectal cancer cells indued by irradiationPrincipal Investigator
- Principal Investigator
  
  Kawai Kazushige
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
Inhibition of gamma-secretase targeting nuclear NOTCH in colorectal cancer
- Principal Investigator
  
  Nozawa Hiroaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
The relationship between SNPs and pouchitis after pouch operation in patients with ulcerative colitis
- Principal Investigator
  
  Hata Keisuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
Elucidation of the role of CD133 in hypoxia triggered epithelial-mesenchymal transition
- Principal Investigator
  
  Otani Kensuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  National Center for Global Health and Medicine
  The University of Tokyo
Genomic and epigenomic analyses of microsatellite instability-high colorectal cancers
- Principal Investigator
  
  Tanaka Toshiaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  The University of Tokyo
The inhibition of autophagy potentiates anti-oncogenic and anti-angiogenic effect of sulforaphane by inducing apoptosis
- Principal Investigator
  
  Nishikawa Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  The University of Tokyo
SN-38 as a radio-sensitizer for colorectal cancer by suppressing radiation-induced HIF-1a overexpressionPrincipal Investigator
- Principal Investigator
  
  Kawai Kazushige
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
Clinical utilization of teh cell free DNA as tumor biomarker.
- Principal Investigator
  
  EIJI SUNAMI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  The University of Tokyo
Role of autophagy in immunoescape of solid tumor
- Principal Investigator
  
  KITAYAMA JOJI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Other

[Journal Article] Clinical significance of the <i>KRAS G13D</i> mutation in anastomotic recurrence of colorectal cancer2023
- Author(s)
  Matsunaga Keigo、Sasaki Kazuhito、Hata Keisuke、Nozawa Hiroaki、Kawai Kazushige、Murono Koji、Emoto Shigenobu、Yokoyama Yuichiro、Sonoda Hirofumi、Ueda Koji、Kuriyama Sho、Yamada Takeshi、Yoshida Hiroshi、Ishihara Soichiro
- Journal Title
  
  Oncology Letters
  
  Volume: 25 Issue: 5 Pages: 192-192
- DOI
  10.3892/ol.2023.13778
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08811, KAKENHI-PROJECT-21H02778
[Journal Article] Impact of the viability assessment of lateral lymph node metastasis in rectal cancer after neoadjuvant chemoradiotherapy2022
- Author(s)
  Ozaki Kosuke、Kawai Kazushige、Nozawa Hiroaki、Sasaki Kazuhito、Murono Koji、Emoto Shigenobu、Abe Hiroyuki、Ushiku Tetsuo、Ishihara Soichiro
- Journal Title
  
  International Journal of Colorectal Disease
  
  Volume: 37 Issue: 2 Pages: 467-473
- DOI
  10.1007/s00384-021-04085-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09051
[Journal Article] Preoperative diagnosis of obstructive colitis in colorectal cancer patients who underwent self-expandable metallic stent insertion as a bridge to surgery2022
- Author(s)
  Emoto Shigenobu、Yokoyama Yuichiro、Nozawa Hiroaki、Kawai Kazushige、Sasaki Kazuhito、Murono Koji、Kishikawa Junko、Ozawa Tsuyoshi、Abe Shinya、Nagai Yuzo、Anzai Hiroyuki、Sonoda Hirofumi、Ishibashi Rei、Koike Kazuhiko、Ishihara Soichiro
- Journal Title
  
  Asian Journal of Surgery
  
  Volume: Online ahead of print Issue: 12 Pages: 2700-2705
- DOI
  10.1016/j.asjsur.2022.02.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09115
[Journal Article] Artificial Intelligence Program to Predict p53 Mutations in Ulcerative Colitis Associated Cancer or Dysplasia2022
- Author(s)
  Noguchi Tatsuki、Ando Takumi、Emoto Shigenobu、Nozawa Hiroaki、Kawai Kazushige、Sasaki Kazuhito、Murono Koji、Kishikawa Junko、Ishi Hiroaki、Yokoyama Yuichiro、Abe Shinya、Nagai Yuzo、Anzai Hiroyuki、Sonoda Hirofumi、Hata Keisuke、Sasaki Takeshi、Ishihara Soichiro
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: Online ahead of print Issue: 7 Pages: 1072-1080
- DOI
  10.1093/ibd/izab350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09115
[Journal Article] Perineal Approach, the Closest Approach to the Pelvic Floor, in Perineal Hernia Repair After Abdominoperineal Resection2022
- Author(s)
  Komatsu Koichi、Emoto Shigenobu、Abe Shinya、Nozawa Hiroaki、Kawai Kazushige、Sasaki Kazuhito、Murono Koji、Ishihara Soichiro
- Journal Title
  
  Diseases of the Colon & Rectum
  
  Volume: Online ahead of print Issue: 9 Pages: e907-e907
- DOI
  10.1097/dcr.0000000000002442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09115
[Journal Article] Development of a novel apoptosis-based tumor regression grade to assess the efficacy of preoperative chemoradiotherapy for rectal cancer: a retrospective single-center study2021
- Author(s)
  Ozaki Kosuke、Kawai Kazushige、Nozawa Hiroaki、Sasaki Kazuhito、Murono Koji、Ishihara Soichiro
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Issue: 9 Pages: 1679-1688
- DOI
  10.1007/s10147-021-01948-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09051
[Journal Article] Therapeutic effects and limitations of chemoradiotherapy in advanced lower rectal cancer focusing on T4b2021
- Author(s)
  Ozaki Kosuke、Kawai Kazushige、Nozawa Hiroaki、Sasaki Kazuhito、Murono Koji、Emoto Shigenobu、Iida Yuuki、Ishii Hiroaki、Yokoyama Yuichiro、Anzai Hiroyuki、Sonoda Hirofumi、Sugihara Kenichi、Ishihara Soichiro
- Journal Title
  
  International Journal of Colorectal Disease
  
  Volume: 36 Issue: 7 Pages: 1525-1534
- DOI
  10.1007/s00384-021-03936-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22799, KAKENHI-PROJECT-20K09051
[Journal Article] Risk factors for non-reaching of ileal pouch to the anus in laparoscopic restorative proctocolectomy with handsewn anastomosis for ulcerative colitis2021
- Author(s)
  Emoto Shigenobu、Hata Keisuke、Nozawa Hiroaki、Kawai Kazushige、Tanaka Toshiaki、Nishikawa Takeshi、Shuno Yasutaka、Sasaki Kazuhito、Kaneko Manabu、Murono Koji、Iida Yuuki、Ishii Hiroaki、Yokoyama Yuichiro、Anzai Hiroyuki、Sonoda Hirofumi、Ishihara Soichiro
- Journal Title
  
  Intestinal Research
  
  Volume: Online ahead of print Issue: 3 Pages: 313-320
- DOI
  10.5217/ir.2020.00158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09115
[Journal Article] Postoperative chemotherapy is associated with prognosis of stage IV colorectal cancer treated with preoperative chemotherapy/chemoradiotherapy and curative resection2020
- Author(s)
  6)Nozawa H, Sonoda H, Ishii H, Emoto S, Murono K, Kaneko M, Sasaki K, Nishikawa T, Shuno Y, Tanaka T, Kawai K, Hata K, Ishihara S.
- Journal Title
  
  Int J Colorectal Dis
  
  Volume: 35 Issue: 1 Pages: 177-180
- DOI
  10.1007/s00384-019-03461-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10621
[Journal Article] Liver injury among Japanese patients treated using prophylactic enoxaparin after colorectal surgery2020
- Author(s)
  Nozawa H, Emoto S, Sonoda H, Kawai K, Sasaki K, Kaneko M, Murono K, Ishii H, Ishihara S
- Journal Title
  
  Dig Dis Sci
  
  Volume: in press Issue: 8 Pages: 2805-2815
- DOI
  10.1007/s10620-020-06586-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21626
[Journal Article] Metastatic role of mammalian target of rapamycin signaling activation by chemoradiotherapy in advanced rectal cancer.2020
- Author(s)
  4)Shiratori H, Kawai K, Okada M, Nozawa H, Hata K, Tanaka T, Nishikawa T, Shuno Y, Sasaki K, Kaneko M, Murono K, Emoto S, Ishii H, Sonoda H, Ushiku T, Ishihara S.
- Journal Title
  
  Cancer Sci
  
  Volume: in press Issue: 4 Pages: 1291-1302
- DOI
  10.1111/cas.14332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10621
[Journal Article] Change in skeletal muscle index and its prognostic significance in patients who underwent successful conversion therapy for initially unresectable colorectal cancer -observational study-2020
- Author(s)
  Nozawa H, Emoto S, Murono K, Shuno Y, Kawai K, Sasaki K, Sonoda H, Ishii H, Iida Y, Yokoyama Y, Anzai H, Ishihara S
- Journal Title
  
  Ther Adv Gastroenterol
  
  Volume: 13
- DOI
  10.1177/1756284820971197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21626
[Journal Article] Obstruction is associated with perineural invasion in T3/T4 colon cancer2019
- Author(s)
  24)Nozawa H, Morikawa T, Kawai K, Hata K, Tanaka T, Nishikawa T, Sasaki K, Shuno Y, Kaneko M, Hiyoshi M, Murono K, Emoto S, Sonoda H, Fukayama M, Ishihara S
- Journal Title
  
  Colorectal Dis
  
  Volume: 21 Issue: 8 Pages: 917-924
- DOI
  10.1111/codi.14655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10621
[Journal Article] Adjuvant chemotherapy improves prognosis of resectable stage IV colorectal cancer: A comparative study using inverse probability of treatment weighting.2019
- Author(s)
  Nozawa H, Takiyama H, Hasegawa K, Kawai K, Hata K, Tanaka T, Nishikawa T, Sasaki K, Kaneko M, Murono K, Emoto S, Sonoda H, Nakajima J.
- Journal Title
  
  Ther Adv Med Oncol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10621
[Journal Article] Accelerated perineural invasion in colitis-associated cancer -;a retrospective cohort study-2019
- Author(s)
  15)Nozawa H, Hata K, Ushiku T, Kawai K, Tanaka T, Shuno Y, Nishikawa T, Sasaki K, Emoto S, Kaneko M, Murono K, Sonoda H, Ishihara S
- Journal Title
  
  Medicine
  
  Volume: 98 Issue: 42 Pages: e17570-e17570
- DOI
  10.1097/md.0000000000017570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10621
[Journal Article] The combination of temsirolimus and chloroquine increases radiosensitivity in colorectal cancer cells2019
- Author(s)
  Shiratori Hiroshi、Kawai Kazushige、Hata Keisuke、Tanaka Toshiaki、Nishikawa Takeshi、Otani Kensuke、Sasaki Kazuhito、Kaneko Manabu、Murono Koji、Emoto Shigenobu、Sonoda Hirofumi、Nozawa Hiroaki
- Journal Title
  
  Oncology Reports
  
  Volume: 42 Pages: 377-385
- DOI
  10.3892/or.2019.7134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10620
[Journal Article] Association between KRAS G13D mutations and anastomotic recurrence in colorectal cancer: Two case reports.2019
- Author(s)
  Okada S, Hata K, Kawai K, Yamamoto Y, Tanaka T, Nishikawa T, Sasaki K, Kaneko M, Emoto S, Murono K, Nozawa H.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07161
[Journal Article] A Polymorphism in Interleukin-1β Gene Is Associated with the Development of Pouchitis in Japanese Patients with Ulcerative Colitis2019
- Author(s)
  Okada S, Hata K, Shinagawa T, Noguchi T, Tanaka T, Kawai K, Nozawa H, Ishihara S
- Journal Title
  
  Digestion
  
  Volume: in press Issue: 3 Pages: 489-498
- DOI
  10.1159/000503283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10622
[Journal Article] Obstruction is associated with perineural invasion in T3/T4 colon cancer2019
- Author(s)
  Nozawa H, Morikawa T, Kawai K, Hata K, Tanaka T, Nishikawa T, Sasaki K, Shuno Y, Kaneko M, Hiyoshi M, Murono K, Emoto S, Sonoda H, Fukayama M, Ishihara S.
- Journal Title
  
  Colorectal Dis
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10621
[Journal Article] Molecular Subtypes Are Frequently Discordant Between Lesions in Patients With Synchronous Colorectal Cancer: Molecular Analysis of 59 Patients2019
- Author(s)
  ARAKAWA KEIICHI、HATA KEISUKE、NOZAWA HIROAKI、KAWAI KAZUSHIGE、TANAKA TOSHIAKI、NISHIKAWA TAKESHI、SASAKI KAZUHITO、SHUNO YASUTAKA、KANEKO MANABU、HIYOSHI MASAYA、EMOTO SHIGENOBU、MURONO KOJI、SONODA HIROFUMI、OKADA SATOSHI、ISHIHARA SOICHIRO
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Issue: 3 Pages: 1425-1432
- DOI
  10.21873/anticanres.13258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07161
[Journal Article] Venous thromboembolism in colorectal surgery: Incidence, risk factors, and prophylaxis2019
- Author(s)
  Emoto Shigenobu、Nozawa Hiroaki、Kawai Kazushige、Hata Keisuke、Tanaka Toshiaki、Shuno Yasutaka、Nishikawa Takeshi、Sasaki Kazuhito、Kaneko Manabu、Hiyoshi Masaya、Murono Koji、Ishihara Soichiro
- Journal Title
  
  Asian Journal of Surgery
  
  Volume: - Issue: 9 Pages: 863-873
- DOI
  10.1016/j.asjsur.2018.12.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07161
[Journal Article] The component changes of lysophospholipid mediators in colorectal cancer2019
- Author(s)
  Chieko Kitamura , Hirofumi Sonoda, Hiroaki Nozawa, Kuniyuki Kano, Shigenobu Emoto, Koji Murono, Manabu Kaneko, Masaya Hiyoshi, Kazuhito Sasaki, Takeshi Nishikawa, Yasutaka Shuno, Toshiaki Tanaka, Keisuke Hata, Kazushige Kawai, Junken Aoki and Soichiro Ishihara
- Journal Title
  
  Tumor Biology
  
  Volume: 41 (5) Issue: 5 Pages: 1-9
- DOI
  10.1177/1010428319848616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07194
[Journal Article] The influence of neoadjuvant chemoradiation for lower rectal cancer on urinary function2019
- Author(s)
  Hirata Yugo、Nozawa Hiroaki、Kawai Kazushige、Hata Keisuke、Tanaka Toshiaki、Nishikawa Takeshi、Otani Kensuke、Sasaki Kazuhito、Kaneko Manabu、Emoto Shigenobu
- Journal Title
  
  Asian Journal of Surgery
  
  Volume: - Issue: 7 Pages: 731-739
- DOI
  10.1016/j.asjsur.2018.11.004
- Open Access
- Data Source
  KAKENHI-PROJECT-16K07161
[Journal Article] Prognostic significance of doubling time in patients undergoing radical surgery for metachronous peritoneal metastases of colorectal cancer2019
- Author(s)
  Miyake Hiroaki、Murono Koji、Nagata Hiroshi、Nozawa Hiroaki、Kawai Kazushige、Hata Keisuke、Tanaka Toshiaki、Nishikawa Takeshi、Shuno Yasutaka、Sasaki Kazuhito、Ishihara Soichiro
- Journal Title
  
  International Journal of Colorectal Disease
  
  Volume: - Issue: 5 Pages: 801-809
- DOI
  10.1007/s00384-019-03259-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07161
[Journal Article] Neoadjuvant imatinib therapy in rectal gastrointestinal stromal tumors2018
- Author(s)
  Kaneko Manabu、Emoto Shigenobu、Murono Koji、Sonoda Hirofumi、Hiyoshi Masaya、Sasaki Kazuhito、Shuno Yasutaka、Nishikawa Takeshi、Tanaka Toshiaki、Hata Keisuke、Kawai Kazushige、Nozawa Hiroaki
- Journal Title
  
  Surgery Today
  
  Volume: - Issue: 6 Pages: 460-466
- DOI
  10.1007/s00595-018-1737-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07161
[Journal Article] Safety of intraperitoneal paclitaxel combined with conventional chemotherapy for colorectal cancer with peritoneal carcinomatosis: a phase I trial2018
- Author(s)
  Murono Koji、Nagata Hiroshi、Ishimaru Kazuhiro、Emoto Shigenobu、Kaneko Manabu、Hiyoshi Masaya、Sasaki Kazuhito、Otani Kensuke、Shuno Yasutaka、Nishikawa Takeshi、Tanaka Toshiaki、Hata Keisuke、Kawai Kazushige、Nozawa Hiroaki、Muro Kei、Ishihara Soichiro
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: 83 Issue: 1 Pages: 145-150
- DOI
  10.1007/s00280-018-3714-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07161
[Journal Article] Correlations between the Recurrence Patterns and Sizes of Lateral Pelvic Lymph Nodes before and after Chemoradiotherapy in Patients with Lower Rectal Cancer2018
- Author(s)
  Shiratori Hiroshi、Kawai Kazushige、Hata Keisuke、Tanaka Toshiaki、Nishikawa Takeshi、Sasaki Kazuhito、Kaneko Manabu、Murono Koji、Emoto Shigenobu、Morikawa Teppei、Fukayama Masashi、Nozawa Hiroaki
- Journal Title
  
  Oncology
  
  Volume: 96 Issue: 1 Pages: 33-43
- DOI
  10.1159/000492493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07161
[Journal Article] Level of arterial ligation in sigmoid colon and rectal cancer surgery.2016
- Author(s)
  Yasuda K, Kawai K, Ishihara S, Murono K, Otani K, Nishikawa T, Tanaka T, Kiyomatsu T, Hata K, Nozawa H, Yamaguchi H, Aoki S, Mishima H, Maruyama T, Sako A, Watanabe T.
- Journal Title
  
  World Journal of Surgical Oncology
  
  Volume: 14 Issue: 1
- DOI
  10.1186/s12957-016-0819-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462005
[Journal Article] Intraoperative colonoscopy in patients with colorectal cancer: A review of recent developments.2016
- Author(s)
  Kawai K, Iida Y, Ishihara S, Yamaguchi H, Nozawa H, Hata K, Kiyomatsu T, Tanaka T, Nishikawa T, Yasuda K, Otani K, Murono K, Watanabe T.
- Journal Title
  
  Digestive Endoscopy
  
  Volume: 未定 Issue: 6 Pages: 633-640
- DOI
  10.1111/den.12663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462005
[Journal Article] CD133 Expression at the Metastatic Site Predicts Patients' Outcome in Colorectal Cancer with Synchronous Liver Metastasis.2016
- Author(s)
  Kishikawa J, Kazama S, Oba K, Hasegawa K, Anzai H, Harada Y, Abe H, Matsusaka K, Hongo K, Oba M, Yasuda K, Otani K, Nishikawa T, Tanaka T, Tanaka J, Kiyomatsu T, Hata K, Kawai K, Nozawa H, Yamaguchi H, Ishihara S, Sunami E, Ushiku T, Kitayama J, Fukayama M, Kokudo N, Watanabe T.
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462005
[Journal Article] Prognostic impact of lymph node dissection is different for male and female colon cancer patients: a propensity score analysis in a multicenter retrospective study2016
- Author(s)
  Ishihara S, Otani K, Yasuda K, Nishikawa T, Tanaka T, Tanaka J, Kiyomatsu T, Kawai K, Hata K, Nozawa H, Kazama S, Yamaguchi H, Sunami E, Kitayama J, Sugihara K, Watanabe T.
- Journal Title
  
  International Journal of colorectal disease
  
  Volume: 未定 Issue: 6 Pages: 1149-1155
- DOI
  10.1007/s00384-016-2558-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462005
[Journal Article] Prediction of the preoperative chemoradiotherapy response for rectal cancer by peripheral blood lymphocyte subsets.2015
- Author(s)
  Tada N, Kawai K, Tsuno NH, Ishihara S, Yamaguchi H, Sunami E, Kitayama J, Oba K, Watanabe T.
- Journal Title
  
  World J Surg Oncol
  
  Volume: 13 Issue: 1 Pages: 30-30
- DOI
  10.1186/s12957-014-0418-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300337, KAKENHI-PROJECT-25253080
[Journal Article] Characteristics and prognosis of colorectal cancer associated with rheumatic disease.2015
- Author(s)
  Kishikawa J, Kawai K, Tsuno N, Yamaguchi H, Ishihara S, Sunami E, Watanabe T.
- Journal Title
  
  Int Surg
  
  Volume: [Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300337
[Journal Article] Prognostic Impact of Histologic Type in Curatively Resected Stage IV Colorectal Cancer: A Japanese Multicenter Retrospective Study.2015
- Author(s)
  Shibata J, Kawai K, Nishikawa T, Tanaka T, Tanaka J, Kiyomatsu T, Hata K, Nozawa H, Kazama S, Yamaguchi H, Ishihara S, Sunami E, Kitayama J, Sugihara K, Watanabe T.
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: Suppl 3 Issue: S3 Pages: 621-629
- DOI
  10.1245/s10434-015-4846-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462005, KAKENHI-PROJECT-25253080
[Journal Article] Prognostic Significance of the Lymph Node Ratio in Stage IV Colorectal Cancer Patients who have Undergone Curative Resection.2015
- Author(s)
  Ozawa T, Ishihara S, Nishikawa T, Tanaka T, Tanaka J, Kiyomatsu T, Hata K, Kawai K, Nozawa H, Kanazawa T, Kazama S, Yamaguchi H, Sunami E, Kitayama J, Watanabe T.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 22 Issue: 5 Pages: 1513-9
- DOI
  10.1245/s10434-014-4184-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300337, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670570
[Journal Article] Nomogram prediction of metachronous colorectal neoplasms in patients with colorectal cancer.2015
- Author(s)
  Kawai K, Ishihara S, Yamaguchi H, Sunami E, Kitayama J, Miyata H, Watanabe T.
- Journal Title
  
  Ann Surg
  
  Volume: 261 Issue: 5 Pages: 926-32
- DOI
  10.1097/sla.0000000000000881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300337, KAKENHI-PROJECT-25253080
[Journal Article] A phase I dose escalation study of oxaliplatin plus oral S-1 and pelvic radiation in patients with locally advanced rectal cancer (SHOGUN trial).2015
- Author(s)
  Ishihara S, Matsusaka S, Kondo K, Horie H, Uehara K, Oguchi M, Murofushi K, Ueno M, Mizunuma N, Shinbo T, Kato D, Okuda J, Hashiguchi Y, Nakazawa M, Sunami E, Kawai K, Yamashita H, Okada T, Ishikawa Y, Nakajima T, Watanabe T.
- Journal Title
  
  Radiat Oncol
  
  Volume: 10 Issue: 1 Pages: 24-24
- DOI
  10.1186/s13014-015-0333-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300337, KAKENHI-PROJECT-25253080
[Journal Article] CD133 Expression in Lymph Node Metastases Is Associated with Tumor Aggressiveness During Lymph Node Metastasis in Colorectal Cancer.2015
- Author(s)
  Kazama S, Kishikawa J, Yasuda K, Otani K, Nishikawa T, Tanaka T, Tanaka J, Kiyomatsu T, Kawai K, Hata K, Nozawa H, Yamaguchi H, Ishihara S, Sunami E, Watanabe T. Anticancer Res. 2015 Dec;35(12):6599-605.
- Journal Title
  
  Anticancer Research
  
  Volume: 35 Pages: 6599-605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462005
[Journal Article] A multicenter phase II study of preoperative chemoradiotherapy with S-1 plus oxaliplatin for locally advanced rectal cancer (SHOGUN trial).2015
- Author(s)
  Matsusaka S, Ishihara S, Kondo K, Horie H, Uehara K, Oguchi M, Murofushi K, Ueno M, Mizunuma N, Shimbo T, Kato D, Okuda J, Hashiguchi Y, Nakazawa M, Sunami E, Kawai K, Yamashita H, Okada T, Ishikawa Y, Nakajima T, Watanabe T.
- Journal Title
  
  Radiotherapy and Oncology
  
  Volume: 116 Issue: 2 Pages: 209-13
- DOI
  10.1016/j.radonc.2015.08.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462005, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25462070
[Journal Article] Detection of carcinoembryonic antigen mRNA in peritoneal lavage by the transcription-reverse transcription concerted method indicates poor prognosis in patients with stage II and III colon cancer.2015
- Author(s)
  Murono K, Kazama S, Yamaguchi H, Kawai K, Ishihara S, Sunami E, Kitayama J, Satoh Y, Kurihara M, Yatomi Y, Watanabe T.
- Journal Title
  
  Surgery
  
  Volume: 157 Issue: 2 Pages: 322-30
- DOI
  10.1016/j.surg.2014.09.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300337, KAKENHI-PROJECT-24591984, KAKENHI-PROJECT-25253080
[Journal Article] Large Colorectal Carcinoma Is Predictive of Recurrence After Adjuvant Chemotherapy Using Oxaliplatin.2015
- Author(s)
  Nozawa H, Nishikawa T, Tanaka T, Tanaka J, Kiyomatsu T, Kawai K, Hata K, Kazama S, Yamaguchi H, Ishihara S, Sunami E, Kitayama J, Watanabe T.
- Journal Title
  
  Anticancer Research
  
  Volume: 35 Pages: 5073-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462005
[Journal Article] Incidence and prognostic significance of positive peritoneal lavage in colorectal cancer.2015
- Author(s)
  Nishikawa T, Sunami E, Tanaka T, Tanaka J, Kiyomatsu T, Kawai K, Hata K, Kazama S, Nozawa H, Ishihara S, Watanabe T.
- Journal Title
  
  Surg Today
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300337
[Journal Article] Nomograms for colorectal cancer: A systematic review.2015
- Author(s)
  Kawai K, Sunami E, Yamaguchi H, Ishihara S, Kazama S, Nozawa H, Hata K, Kiyomatsu T, Tanaka J, Tanaka T, Nishikawa T, Kitayama J, Watanabe T.
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 21 Issue: 41 Pages: 11877-86
- DOI
  10.3748/wjg.v21.i41.11877
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462005
[Journal Article] Proximal shift of colorectal cancer along with aging.2014
- Author(s)
  Iida Y, Kawai K, Tsuno NH, Ishihara S, Yamaguchi H, Sunami E, Kitayama J, Watanabe T.
- Journal Title
  
  Clin Colorectal Cancer
  
  Volume: 13 Issue: 4 Pages: 213-8
- DOI
  10.1016/j.clcc.2014.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300337, KAKENHI-PROJECT-24591984
[Journal Article] Nuclear Notch3 expression is associated with tumor recurrence in patients with stage II and III colorectal cancer.2014
- Author(s)
  Ozawa T, Kazama S, Akiyoshi T, Murono K, Yoneyama S, Tanaka T, Tanaka J, Kiyomatsu T, Kawai K, Nozawa H, Kanazawa T, Yamaguchi H, Ishihara S, Sunami E, Kitayama J, Morikawa T, Fukayama M, Watanabe T.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 21 Issue: 8 Pages: 2650-8
- DOI
  10.1245/s10434-014-3659-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300337, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25861220
[Journal Article] Changes in the plasma levels of cytokines/chemokines for predicting the response to chemoradiation therapy in rectal cancer patients.2014
- Author(s)
  Tada N, Tsuno NH, Kawai K, Murono K, Nirei T, Ishihara S, Sunami E, Kitayama J, Watanabe T.
- Journal Title
  
  Oncol Rep
  
  Volume: 31 Issue: 1 Pages: 463-71
- DOI
  10.3892/or.2013.2857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300337, KAKENHI-PROJECT-24390309, KAKENHI-PROJECT-24659620, KAKENHI-PROJECT-25253080
[Journal Article] Prognostic impact of primary tumor resection and lymph node dissection in stage IV colorectal cancer with unresectable metastasis: a propensity score analysis in a multicenter retrospective study.2014
- Author(s)
  Ishihara S, Hayama T, Yamada H, Nozawa K, Matsuda K, Miyata H, Yoneyama S, Tanaka T, Tanaka J, Kiyomatsu T, Kawai K, Nozawa H, Kanazawa T, Kazama S, Yamaguchi H, Sunami E, Kitayama J, Hashiguchi Y, Sugihara K, Watanabe T.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 21 Issue: 9 Pages: 2949-55
- DOI
  10.1245/s10434-014-3719-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300337, KAKENHI-PROJECT-24390309, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670570
[Presentation] リゾリン脂質の質量分析技術を用いた、大腸癌および潰瘍性大腸炎関連大腸癌の解析2020
- Author(s)
  園田洋史、北村智恵子、安西紘幸、横山雄一郎、石井博章、飯田祐基、室野浩司、江本成伸、金子学、佐々木和人、川合一茂、野澤宏彰、石原聡一郎
- Organizer
  第82回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-18K07194
[Presentation] ステント治療を行った大腸癌の病理に端を発した神経周囲侵襲のリスク因子に関する研究2019
- Author(s)
  野澤宏彰、園田洋史、舘川裕一、畑啓介、川合一茂、田中敏明、秀野泰隆、西川武司、佐々木和人、金子学、江本成伸、室野浩司、石井博章、石原聡一郎
- Organizer
  日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10621
[Presentation] 大腸癌におけるリゾホスファチジルイノシトールの局在の質量顕微鏡を用いた解析2019
- Author(s)
  北村智恵子, 園田洋史, 可野邦行, 田中敏明, 畑啓介, 川合一茂, 野澤宏彰, 青木淳賢, 石原聡一郎
- Organizer
  日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K07194
[Presentation] 日本人の回腸嚢炎発症とUC関連大腸癌のリスク因子の検討2019
- Author(s)
  岡田聡、畑啓介, 秀野泰隆, 西川武司, 佐々木和人, 金子学, 江本成伸, 室野浩司, 石井博章, 園田洋史, 田中敏明, 川合一茂, 野澤宏彰, 石原聡一郎
- Organizer
  第10回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10622
[Presentation] 大腸癌におけるリゾリン脂質性メディエーターの組成変化に関する検討2019
- Author(s)
  北村智恵子, 園田洋史, 可野邦行, 江本成伸, 室野浩司, 金子学, 日吉雅也, 佐々木和人, 秀野泰隆, 西川武司, 田中敏明, 畑啓介, 川合一茂, 青木淳賢, 野澤宏彰
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K07194
[Presentation] 大腸癌におけるリゾリン脂性メディエーターの組成変化に関する検討2019
- Author(s)
  北村智恵子, 園田洋史, 室野浩司, 江本成伸, 日吉雅也, 金子学, 佐々木和人, 西川武司, 秀野泰隆, 田中敏明, 畑啓介, 川合一茂, 野澤宏彰, 石原聡一郎
- Organizer
  日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K07194
[Presentation] Risk factors and therapeutic significance for inguinal lymph node metastasis in advanced lower rectal cancer.2019
- Author(s)
  Nozawa H, Shiratori H, Kawai K, Hata K, Tanaka T, Nishikawa T, Shuno Y, Sasaki K, Kaneko M, Emoto S, Murono K, Sonoda H, Ishii H, Ishihara S.
- Organizer
  ASCO 2019 Breakthrough: A Global Summit for Oncology Innovators.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10621
[Presentation] 大腸癌におけるリゾリン脂質性メディエーターの組成変化に関する検討2018
- Author(s)
  北村智恵子、園田洋史、可野邦行、江本成伸、室野浩司、金子学、日吉雅也、佐々木和人、秀野泰隆、西川武司、田中敏明、畑啓介、川合一茂、青木淳賢、野澤宏彰
- Organizer
  日本癌治療学会
- Data Source
  KAKENHI-PROJECT-18K07194
[Presentation] 大腸癌細胞におけるSN-38のHIF-1α抑制による放射線増感剤としての作用2017
- Author(s)
  奥野貴之、川合一茂、石原聡一郎、大谷研介、西川武司、田中敏明、清松知充、畑啓介、野澤宏彰、渡邉聡明
- Organizer
  第72回日本消化器外科学会総会
- Place of Presentation
  金沢
- Year and Date
  2017-07-20
- Data Source
  KAKENHI-PROJECT-26462005
[]

1. 石原聡一郎 (00376443)

# of Collaborated Projects: 15 results

# of Collaborated Products: 35 results
2. Nozawa Hiroaki (80529173)

# of Collaborated Projects: 14 results

# of Collaborated Products: 33 results
3. Hata Keisuke (60526755)

# of Collaborated Projects: 10 results

# of Collaborated Products: 26 results
4. 渡邉聡明 (80210920)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
5. Tanaka Toshiaki (30647540)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
6. YAMAGUCHI Hironori (20376445)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
7. SONODA HIROFUMI (80770205)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
8. EIJI SUNAMI (70345205)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
9. TSUNO Hirokazu (50282637)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. Nishikawa Takeshi (00749799)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
11. KITAYAMA JOJI (20251308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YAMASHITA Hiroharu (50599397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Otani Kensuke (20757497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Kaneko Manabu (10790850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Emoto Shigenobu (30803267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. 河津正人 (20401078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 清松知充 (00625303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 佐々木和人 (00781238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YOSHIDA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 渡辺聡明

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
21. 津野ネルソン

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
22. 山田岳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 飯田祐基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawai Kazushige 川合 一茂

KAWAI Kazushige 川合 一茂

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直腸癌化学放射線療法における遺伝子変異タイプと放射線耐性機構の活性化の相関の解明Principal Investigator

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Epithelial Mesenchymal Transition of rectal cancer cells indued by irradiationPrincipal Investigator

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SN-38 as a radio-sensitizer for colorectal cancer by suppressing radiation-induced HIF-1a overexpressionPrincipal Investigator

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Kawai Kazushige 川合一茂

KAWAI Kazushige 川合一茂