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Okamoto Koji  岡本 好司

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… Alternative Names

岡本 好司  オカモト コウジ

OKAMOTO Koji  岡本 好司

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Researcher Number 80572247
Other IDs
Affiliation (Current) 2025: 東北大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help 2024 – 2025: 東北大学, 大学病院, 講師
2021 – 2022: 東北大学, 大学病院, 講師
2020: 東北大学, 東北メディカル・メガバンク機構, 非常勤講師
2014: 東京大学, 医学部附属病院, 助教
2012: 東京大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 90130:Medical systems-related
Except Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Kidney internal medicine
Keywords
Except Principal Investigator
ChREBP / 構造最適化 / 糖尿病性腎症 / 肝星細胞 / 肝細胞 / NASH / NAFLD / 近位尿細管 / RNAシ ークエンス / 糖尿病性腎臓病 … More / モデルマウス / 創薬 / 新規創薬 / 転写因子 / ハイスループットスクリーニング / 化合物ライブラリー / 免疫沈降法 / ChIPアッセイ / CRISPR-Cas9システム / ゲノム医科学 / ヘパラン硫酸 / 腎臓病学 / 蛋白尿 / ヘパラン硫酸プロテオグリカン / HLA / ゲノム解析 / 膜性腎症 / ネフローゼ症候群 Less
  • Research Projects

    (5 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (14 People)
  •  深層学習を使った腎糸球体病変の組織診断定量化アルゴリズムの開発Principal Investigator

    • Principal Investigator
      岡本 好司
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Tohoku University
  •  糖質応答転写因子ChREBPの新規阻害薬を用いた糖尿病性腎臓病の病態解明・制御

    • Principal Investigator
      菅原 明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tohoku University
  •  新規ChREBP阻害薬の標的遺伝子に対するPerturbシークエンスを用いたNAFLDの病態制御

    • Principal Investigator
      菅原 明
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Tohoku University
  •  Innovation of a novel DN medication by targeting ChREBP

    • Principal Investigator
      Sugawara Akira
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tohoku University
  •  Elucidation to Pathogenetic Mechanism of Nephrotic Proteinuria through Genetic and Functional Analysis

    • Principal Investigator
      NOIRI Eisei
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo

All 2022 2021 2014 2013 2012

All Journal Article Presentation

  • [Journal Article] The physiological and pathophysiological roles of carbohydrate response element binding protein in the kidney2022

    • Author(s)
      Yokoyama Atsushi、Suzuki Susumu、Okamoto Koji、Sugawara Akira
    • Journal Title

      Endocr J

      Volume: 69 Issue: 6 Pages: 605-612

    • DOI

      10.1507/endocrj.EJ22-0083

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11439, KAKENHI-PROJECT-20H04099, KAKENHI-PROJECT-21K19692
  • [Journal Article] siRNA Delivery Targeting to the Lung via Agglutination-Induced Accumulation and Clearance of Cationic Tetraamino Fullerene2014

    • Author(s)
      K. Minami, K. Okamoto, K. Doi, K. Harano, E. Noiri, E. Nakamura
    • Journal Title

      Sci. Rep.

      Volume: 4 Issue: 1 Pages: 4916-4916

    • DOI

      10.1038/srep04916

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22000008, KAKENHI-PROJECT-24390212
  • [Journal Article] Protection of glucagon-like peptide-1 in cisplatin-induced renal injury elucidates gut-kidney connection.2013

    • Author(s)
      Katagiri D, Hamasaki Y, Doi K, Okamoto K, Negishi K, Nangaku M, Noiri E
    • Journal Title

      J Am Soc Nephrol

      Volume: 24 Issue: 12 Pages: 2034-2043

    • DOI

      10.1681/asn.2013020134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390212
  • [Journal Article] Inhibition of glucose-stimulated insulin secretion by KCNJ15, a newly identified susceptibility gene for type 2 diabetes.2012

    • Author(s)
      Okamoto K, et al
    • Journal Title

      Diabetes

      Volume: 61 Pages: 1734-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390212
  • [Presentation] Examination of the effectiveness of diabetic nephropathy treatment targeting ChREBP activity2022

    • Author(s)
      Suzuki S, Yokoyama A, Okamoto K, Iwabuchi Y, Sugawara A.
    • Organizer
      アメリカ内分泌学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H04099
  • [Presentation] 糖尿病性腎症の発症・進展における腎近位尿細管ChREBPの機能解析2021

    • Author(s)
      西澤翔輝、野呂英理香、鈴木 歩、横山 敦、岡本好司、菅原 明
    • Organizer
      第94回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H04099
  • [Presentation] Sulfatase 2, Identified By Genome Association Analysis, Contributes to Protection against Nephrotic Syndrome2014

    • Author(s)
      Kenjiro Honda, MD, PhD, Koji Okamoto, MD, PhD, Kent Doi, MD, PhD, FASN, Masaomi Nangaku, MD, PhD, Katsushi Tokunaga, Eisei Noiri, MD, PhD, FASN
    • Organizer
      米国腎臓学会
    • Place of Presentation
      フィラデルフィア会議場
    • Year and Date
      2014-11-15
    • Data Source
      KAKENHI-PROJECT-24390212
  • 1.  Sugawara Akira (90270834)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 2.  岩渕 好治 (20211766)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 3.  横山 敦 (20572332)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 4.  NOIRI Eisei (00301820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  TOKUNAGA Katsushi (40163977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  DOI Kent (80505892)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  HAMASAKI Yoshifumi (20617774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  NEGISHI Kosuke (40572219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  広川 貴次 (20357867)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  沢津橋 俊 (70535103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  井上 淳 (60455821)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OKAMOTO Toshihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  中村 栄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  浜崎 敬文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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