Xu Mingli 徐明利

… Alternative Names

XU Mingli 徐明利

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Researcher Number	80597964
Other IDs
Affiliation (Current)	2025: 東京医科大学, 医学部, 客員講師
Affiliation (based on the past Project Information) *help	2015 – 2023: 東京医科大学, 医学部, 客員講師 2013: 慶應義塾大学, 医学部, 特任助教 2012 – 2013: 慶應義塾大学, 医学部, 助教 2011: 東京医科大学, 医学部, ポストドクター
Review Section/Research Field	Principal Investigator Experimental pathology / Basic Section 59010:Rehabilitation science-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator IL-27 / IL-23 / 脳卒中 / 脊髄損傷 / リハビリテーション治療 / 炎症反応、 / 脳血液関門タイトジャンクション / 漢方薬 / 炎症反応 / 慢性期 … More / 脳梗塞 / 骨髄由来免疫抑制細胞 / がん治療応用 / CML / 抗腫瘍作用 / BCR-ABL / 慢性骨髄性白血病 / がん治療 / heterodimeric cytokine / p19 / EBI3 / Notch / IL-17 / IL-22 Less

脳卒中・脊髄損傷の後遺障害のリハビリテーション治療への漢方薬の応用Principal Investigator
- Principal Investigator
  
  徐明利
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Tokyo Medical University
Comprehensive study on IL-27, one of the IL-12 family cytokines, aiming at its clinical application for cancer immunotherapyPrincipal Investigator
- Principal Investigator
  
  Xu Mingli
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Medical University
Identification and functional analysis of a novel IL-6/IL-12 family cytokinePrincipal Investigator
- Principal Investigator
  
  Xu Mingli
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical University
New mechanism whereby IL-23 regulates immune responses through Notch signallingPrincipal Investigator
- Principal Investigator
  
  XU Mingli
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University
  Tokyo Medical University

All 2024 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011

All Journal Article Presentation

[Journal Article] Induction of potent antitumor immunity by intradermal <scp>DNA</scp> injection using a novel needle‐free pyro‐drive jet injector2022
- Author(s)
  Inoue Shinya、Mizoguchi Izuru、Sonoda Jukito、Sakamoto Eri、Katahira Yasuhiro、Hasegawa Hideaki、Watanabe Aruma、Furusaka Yuma、Xu Mingli、Yoneto Toshihiko、Sakaguchi Naoki、Terai Kazuhiro、Yamashita Kunihiko、Yoshimoto Takayuki
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 1 Pages: 34-47
- DOI
  10.1111/cas.15542
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11227, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-22K07504, KAKENHI-PROJECT-22K12772, KAKENHI-PROJECT-23K09087, KAKENHI-PROJECT-21K12256
[Journal Article] 骨髄由来抑制細胞の分子機序2021
- Author(s)
  井上槙也、古阪悠馬、渡邉有麻、坂本恵梨、長谷川英哲、村上史浩、米戸敏彦、徐　明利、片平泰弘、溝口　出、善本隆之
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 75(6) Pages: 1-9
- Data Source
  KAKENHI-PROJECT-18K07333
[Journal Article] A chaperone-like role for EBI3 in collaboration with calnexin under inflammatory conditions.2021
- Author(s)
  Watanabe A, Mizoguchi I, Hasegawa H, Katahira Y, Inoue S, Sakamoto E, Furusaka Y, Sekine A, Miyakawa S, Murakami F, Xu M, Yoneto T, Yoshimoto T.
- Journal Title
  
  Front Immunol.
  
  Volume: 12 Pages: 757669-757669
- DOI
  10.3389/fimmu.2021.757669
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06570, KAKENHI-PROJECT-19K09105, KAKENHI-PROJECT-21K09779, KAKENHI-PROJECT-21K11227, KAKENHI-PROJECT-21K12256
[Journal Article] IL-23p19 and CD5 antigen-like form a possible heterodimeric cytokine and contribute to experimental autoimmune encephalomyelitis development.2021
- Author(s)
  Hasegawa H, Mizoguchi I, Orii N, Inoue S, Katahira Y, Yonteo T, Mingli X, Miyazaki T, Yoshimoto T
- Journal Title
  
  Sci Rep.
  
  Volume: 11(1) Issue: 1 Pages: 5266-5266
- DOI
  10.1038/s41598-021-84624-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06570, KAKENHI-PROJECT-19K09105, KAKENHI-PROJECT-20K22885, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658, KAKENHI-PROJECT-21K09779, KAKENHI-PROJECT-21K11227, KAKENHI-PROJECT-21K12256
[Journal Article] EBV-induced gene 3 augments IL-23Rα protein expression through a chaperone calnexin.2020
- Author(s)
  Mizoguchi I, Ohashi M, Hasegawa H, Chiba Y, Orii N, Inoue S, Kawana C, Xu M, Sudo K, Fujita K, Kuroda M, Hashimoto S, Matsushima K, and Yoshimoto T.
- Journal Title
  
  J Clin Invest.
  
  Volume: 130(11) Issue: 11 Pages: 6124-6140
- DOI
  10.1172/jci122732
- NAID
  120007052824
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06570, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658
[Journal Article] Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases.2018
- Author(s)
  Chiba Y, Mizoguchi I, Hasegawa H, Ohashi M, Orii N, Nagai T, Sugahara M, Miyamoto Y, Xu M, Owaki T, Yoshimoto T.
- Journal Title
  
  Cell. Mol. Life Sci.
  
  Volume: 75 Issue: 8 Pages: 1363-1376
- DOI
  10.1007/s00018-017-2724-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-16J04160, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658
[Journal Article] Worldwide consortium-based validation of Immunoscore for the classification of colon cancer.2018
- Author(s)
  Pages F, Mlecnik B, Xu M, Kawakami Y, Galon J, et al.
- Journal Title
  
  Lancet
  
  Volume: 391(10135) Issue: 10135 Pages: 2128-2139
- DOI
  10.1016/s0140-6736(18)30789-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-17H01540
[Journal Article] Protective effects against tumors and infection by IL-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors.2018
- Author(s)
  Orii N, Mizoguchi I, Chiba Y, Hasegawa H, Ohashi M, Xu M, Nagai T, Ochiai M, Mochizuki Y, Owaki T, Yoshimoto T.
- Journal Title
  
  Oncoimmunology
  
  Volume: - Issue: 5 Pages: e1421892-e1421892
- DOI
  10.1080/2162402x.2017.1421892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658
[Journal Article] Interleukin-27 exerts its antitumor effects by promoting differentiation of hematopoietic stem cells to M1 macrophages.2018
- Author(s)
  Chiba Y, Mizoguchi I, Furusawa J, Hasegawa H, Ohashi M, Xu M, Owaki T, Yoshimoto T.
- Journal Title
  
  Cancer Res.
  
  Volume: 78 Issue: 1 Pages: 182-194
- DOI
  10.1158/0008-5472.can-17-0960
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-16J04160, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658
[Journal Article] Prediction of chemical respiratory and contact sensitizers by OX40L expression in dendritic cells using a novel 3D co-culture system.2017
- Author(s)
  Mizoguchi I, Ohashi M, Chiba Y, Hasegawa H, Xu M, Owaki T, Yoshimoto T.
- Journal Title
  
  Front. Immunol.
  
  Volume: 8 Pages: 929-929
- DOI
  10.3389/fimmu.2017.00929
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433
[Journal Article] Expanding Diversity in Molecular Structures and Functions of the IL-6/IL-12 Heterodimeric Cytokine Family2016
- Author(s)
  Hasegawa Hideaki, Izuru Mizoguchi, Yukino Chiba, Mio Ohashi, Mingli Xu, and Takayuki Yoshimoto
- Journal Title
  
  Frontires in Immunolgy
  
  Volume: -
- DOI
  10.3389/fimmu.2016.00479
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J04160, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433
[Journal Article] Therapeutic potential of interleukin-27 against cancers in preclinical mouse models.2015
- Author(s)
  Mizoguchi, I., Chiba, Y., Furusawa, J., Xu, M., Tsunoda, R., Higuchi, K., and Yoshimoto,
- Journal Title
  
  Oncoimmunology
  
  Volume: 4(10) Issue: 10 Pages: e1042200-e1042200
- DOI
  10.1080/2162402x.2015.1042200
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433
[Journal Article] Potential clinical application of interleukin-27 as an antitumor agent.2015
- Author(s)
  Yoshimoto, T., Chiba, Y., Furusawa, J., Xu, M., Tsunoda, R., Higuchi, K., and Mizoguchi, I.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106(9) Issue: 9 Pages: 1103-1110
- DOI
  10.1111/cas.12731
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433
[Journal Article] Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases.2013
- Author(s)
  Qu N, Xu M, Mizoguchi I, Furusawa J, Kaneko K, Watanabe K, Mizuguchi J, Itoh M,Kawakami Y, Yoshimoto T.
- Journal Title
  
  Clin Dev Immunol.
  
  Volume: 2013:968549 Pages: 1-13
- DOI
  10.1155/2013/968549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-23590475, KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24590243, KAKENHI-PROJECT-24659595, KAKENHI-PROJECT-24790091, KAKENHI-PUBLICLY-25118727, KAKENHI-PROJECT-25670506
[Journal Article] Identification of a novel role of Septin 10 in Paclitaxel-resistance in cancers through a functional genomics screen2012
- Author(s)
  Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, Ohyashiki J, Kuroda M
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 4 Pages: 821-827
- DOI
  10.1111/j.1349-7006.2012.02221.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592146, KAKENHI-PROJECT-22590367, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23590417, KAKENHI-PROJECT-23590475, KAKENHI-PROJECT-23590993, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-24370058
[Journal Article] がん免疫病態と免疫動態の評価2012
- Author(s)
  河上裕、谷口智憲、中村公子、川瀬芳恵、野路しのぶ、大泉梓、南雲春菜、長谷川舞、徐明利、岡本正人、桜井敏晴、藤田知信
- Journal Title
  
  血液フロンティア
  
  Volume: Vol.22,No.8 Pages: 1183-1190
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] サイトカインのすべて　IL-352012
- Author(s)
  徐明利　等
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57 (Suppl. 21) Pages: 220-230
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] サイトカインのすべてIL-352012
- Author(s)
  徐明利、千葉祐規乃、善本隆之
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57(Suppl.21) Pages: 220-230
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Identification of a novel role of septin 10 in paclitaxel-resistance in cancers through a functional genomics screen2012
- Author(s)
  Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, Ohyashiki J, Kuroda M
- Journal Title
  
  Cancer Sci
  
  Volume: 103(4) Pages: 821-827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] サイトカインのすべてIL-272012
- Author(s)
  千葉祐規乃、溝口出、森嶋紀子、徐明利、善本隆之
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57(Suppl.21) Pages: 172-183
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] DCワクチンをリンパ節投与した際の局所滞留性と免疫誘導能の検討2012
- Author(s)
  太田裕士、徐明利、溝口出、高梨正勝、須藤カツ子、黒田雅彦、善本隆之、粕谷和彦、土田明彦、畝崎榮
- Journal Title
  
  東京医科大学雑誌
  
  Volume: 70(4) Pages: 444-449
- NAID
  10031143025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Regulation of the development of acute hepatitis2011
- Author(s)
  Xu, M. et al.
- Journal Title
  
  Eur. J. Immunol.
  
  Volume: 41 Pages: 2828-2839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] IL-12、モデル動物利用マニュアル2011
- Author(s)
  奥村昌恵、徐明利、善本隆之
- Journal Title
  
  LIC
  
  Pages: 266-275
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production2011
- Author(s)
  Xu M, Morishima N, Mizoguchi I, Chiba Y, Fujita K, Kuroda M, Iwakura Y, Cua DJ, Yasutomo K, Mizuguchi J, Yoshimoto T
- Journal Title
  
  Eur J. Immunol
  
  Volume: 41 (10) Pages: 2828-2839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] ヒト乳歯歯髄幹細胞由来馴化培地のX線照射による白髪化に対する保護効果2024
- Author(s)
  片平泰弘、長谷川英哲、井上槙也、渡邉有麻、関根碧水、山岸宇、山口夏輝、徐明利、溝口　出、善本隆之
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K11227
[Presentation] ヒトT細胞の活性化・分化誘導を指標に感作性・アレルギー誘発性を評価する新規代替法の開発2021
- Author(s)
  溝口出、片平泰弘、坂本恵梨、井上槙也、古阪悠馬、渡邉有麻、関根碧水、宮川聡美、長谷川英哲、徐　明利、米戸敏彦、善本隆之
- Organizer
  第34回日本動物実験代替法学会
- Data Source
  KAKENHI-PROJECT-21K11227
[Presentation] 間葉系幹細胞培養上清のIGFBP-4 を介した腫瘍増殖の抑制2021
- Author(s)
  古阪悠馬、片平泰弘、村上史浩、坂本恵梨、渡邉有麻、井上槙也、長谷川英哲、米戸敏彦、徐明利、溝口　出、善本隆之
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11227
[Presentation] 自己免疫性脳脊髄炎発症に関与する新規ヘテロダイマーサイトカインp19/CD5Lの同定とその機能解析2021
- Author(s)
  長谷川英哲、溝口　出、片平泰弘、井上槙也、渡邉有麻、坂本恵梨、古阪悠馬、米戸敏彦、徐明利、宮崎徹、善本隆之
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11227
[Presentation] 化粧品美白成分ロドデノールによる自己免疫性白斑症誘発の作用機序の解明2021
- Author(s)
  坂本恵梨、片平泰弘、井上槙也、古阪悠馬、渡邉有麻、長谷川英哲、米戸敏彦、徐明利、溝口　出、善本隆之
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11227
[Presentation] 活性化T細胞から産生されるIL-23p19サブユニットの役割2020
- Author(s)
  長谷川英哲、溝口　出、折井直子、川名千晶、井上槙也、村上史浩、米戸敏彦、徐　明利、善本隆之
- Organizer
  東京医科大学記念館ポスター発表懇談会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] アレルギー感作性を評価する新規動物実験代替法の開発2020
- Author(s)
  溝口　出、川名千晶、長谷川英哲、折井直子、井上槙也、村上史浩、米戸敏彦、徐　明利、善本隆之
- Organizer
  東京医科大学記念館ポスター発表懇談会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] 化粧品美白成分による白斑症誘発の作用機序の解明とそのin vitro評価法の開発2020
- Author(s)
  坂本恵梨、片平泰弘、井上槙也、古阪悠馬、渡邉有麻、長谷川英哲、米戸敏彦、徐　明利、溝口出、善本隆之
- Organizer
  第33回日本動物実験代替法学会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] Antitumor effects of IL-27 against a mouse chronic myeloid leukemia (CML) model.2019
- Author(s)
  Orii N, Hasegawa H, Xu M, Mizoguchi I, Yoshida H, Yoshimoto T.
- Organizer
  第183回東京医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] 慢性骨髄性白血病(CML)マウスモデルを用いたCML発症におけるIL-27の役割2019
- Author(s)
  折井直子、長谷川英哲、米戸敏彦、徐　明利、大脇敏之、溝口　出、善本隆之
- Organizer
  東京医科大学記念館ポスター発表懇談会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] EBI3, one of subunits shared among the IL-12 cytokine family, plays a critical role in up-regulation of MHC class I during DC maturation.2019
- Author(s)
  Mizoguchi I, Hasegawa H, Orii N, Inoue S, Kawana C, Yoneto T, Xu M, Yoshimoto T.
- Organizer
  17th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] Development of a novel alternative method for evaluation of sensitizing potential and allergenicity by measuring human T cell activation and differentiation in vitro.2019
- Author(s)
  Mizoguchi I, Inoue S, Orii N, Hasegawa H, Xu M, Yoshimoto T.
- Organizer
  第48回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] Antitumor effects of IL-27 against a mouse chronic myeloid leukemia (CML) model.2018
- Author(s)
  Orii, N., Hasegawa, H., Xu, M., Mizoguchi, I., Yoshida, H., and Yoshimoto, T.
- Organizer
  第182回東京医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] Protective role for IL-27 in the development of mouse chronic myeloid leukemia model.2018
- Author(s)
  Orii, N., Mizoguchi, I., Chiba, Y., Hasegawa, H., Xu, M., Ochiai, N., Mochizuki, Y., Owaki, T., and Yoshimoto, T.
- Organizer
  The 45th NATITO CONFERENCE ON Immunological and Molecular Bases for Cancer Immunotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] Antitumor effects of IL-27 against a mouse chronic myeloid leukemia model.2018
- Author(s)
  Orii, N., Hasegawa, H., Xu, M., Mizoguchi, I., Yoshida, H., and Yoshimoto, T.
- Organizer
  第47回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] A novel antitumor activity of IL-27 by promoting the differentiation of HSCs to antitumorigenic M1-like macrophages in tumor-bearing mice.2017
- Author(s)
  Chiba, Y., Ohashi, M., Hasegawa, H., Xu, M., Owaki, T., Mizoguchi, I., and Yoshimoto, T.
- Organizer
  The 2nd International Conference on Cytokine Signaling in Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] A novel role for Epstein-Barr virus-induced gene 3 to augment IL-23 receptor α protein expression through a lectin chaperone calnexin.2017
- Author(s)
  Mizoguchi, I., Ohashi, M., Hasegawa, H., Chiba, Y., Xu, M., and Yoshimoto, T.
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] Prediction of chemical respiratory and contact sensitizers by OX40L expression in dendritic cells using a novel 3D co-culture system.2017
- Author(s)
  Ohashi, M., Mizoguchi, I., Chiba, Y., Hasegawa, H., Xu, M., and Yoshimoto, T.
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] IL-27 induces antitumor activity by promoting differentiation of HSCs to M1-like antitumorigenic macrophages and their mobiliziation into tumor.2016
- Author(s)
  Chiba, Y., Mizoguchi, I., Hasegawa, H., Ohashi, M., C., Xu, M., and Yoshimoto, T.
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] Establishment of a novel in vitro evaluation system for the prediction of respiratory sensitizing potential of chemicals.2016
- Author(s)
  Yoshimoto, T., Ohashi, M., Hasegawa, H., Chiba, Y., Xu, M., and Mizoguchi, I.
- Organizer
  ICCA-LRI and NIHS Workshop
- Place of Presentation
  Awaji Island
- Year and Date
  2016-06-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] Promotion of expansion and differentiation of hematopoietic stem cells by IL-27 into myeloid progenitors to control infection in emergency myelopoiesis.2016
- Author(s)
  Yoshimoto, T., Furusawa, J., Chiba, Y., Xu, M., Hasegawa, H., Nakae, S., Kobayashi, F., Yoshida, H., and Mizoguchi, I. Ohashi, M., Hasegawa, H., and Mizoguchi, I.
- Organizer
  Symposium, 16th International Congress of Immunology
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] 化学物質の呼吸器感作性in vitro評価法の開発2015
- Author(s)
  溝口出、千葉佑規乃、角田廉、徐明利、善本隆之
- Organizer
  第3期LRI研究報告会
- Place of Presentation
  東京
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] 化学物質の呼吸器感作性in vitro評価法の開発2015
- Author(s)
  善本隆之、千葉佑規乃、角田廉、徐明利、溝口出
- Organizer
  第28回日本動物実験代替法学会
- Place of Presentation
  横浜
- Year and Date
  2015-12-10
- Invited
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] Binding of Epstein-Barr virus-induced gene 3 to calnexin enhances its chaperone activity and augments interleukin-23 receptor expression, leading to development of colitis.2015
- Author(s)
  Mizoguchi, I., Chiba, Y., Xu, M., and Yoshimoto, T.
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] Strong correlation of tumor-infiltrating CD8+ and FOXP3+ T cells with favorable prognosis of patients with colon cancer.2013
- Author(s)
  Xu, M. et al.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Strong correlation of tumor-infiltrating CD8^<+> and FOXP3^<+> T cells with favorable prognosis of patients with coloncancer2013
- Author(s)
  Xu M, Noji S, Popivanova B, Okamoto M, Sakurai T, Fujita T, Torigoe T, Sato N, Sugiura F, Okuno K, Hazama S, Oka M, Kawakami Y
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉県
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] IL-27とPoly(1:c)による協調的TRAILとTLR3発現増強を介したメラノーマ腫瘍増殖のTRAIL依存的抑制2012
- Author(s)
  溝口出、千葉祐規乃、徐明利、樋口要、善本隆之、水口純一郎
- Organizer
  第87回東京医科大学・東京薬科大学・免疫アレルギー研究会
- Place of Presentation
  東京
- Year and Date
  2012-05-29
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] DCワクチンをリンパ節投与した際の局所滞留性と免疫誘導能の検討2012
- Author(s)
  太田裕士、徐明利、溝口出、高梨正勝、須藤カツ子、黒田雅彦、善本隆之、粕谷和彦、土田明彦、畝崎榮
- Organizer
  第132年会日本薬学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] 能動免疫療法における免疫誘導・抗腫瘍効果を規定するバイオマーカーの検索2012
- Author(s)
  川瀬芳恵、藤田知信、大泉梓、野路しのぶ、桜井敏晴、南雲春菜、徐明利、中山一、垣見和宏、鳥越俊彦、池田裕明、珠玖洋、岡本正人、河上裕
- Organizer
  第16回日本がん免疫学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production2011
- Author(s)
  Xu M, Morishima N, Mizoguchi I, Chiba Y, Fujita K, Kuroda M, Iwakura Y, Cua DJ, Yasutomo K, Mizuguchi J, Yoshimoto T
- Organizer
  The 98th American Association of Immunologists Annual Meeting
- Place of Presentation
  San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Regulation of the development of acute hepatitis2011
- Author(s)
  Xu, M. et al.
- Organizer
  98th Annual Meeting of AAI
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Regulation of the development of acute hepatitis2011
- Author(s)
  Xu, M. et al.
- Organizer
  第168回東京医科大学医学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] IL-27 enhances poly(I:C)-inducedapoptosisoftumorcells2011
- Author(s)
  Chiba Y, Xu M, Mizoguchi I, Mizuguchi J, Yoshimoto T
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Regulation of inflammatory immune responses leading to the development of bone destructive autoimmune disease rheumatoid arthritis by IL-27. Bio-Rhematology Internation Congress (BRIC) Tokyo2011
- Author(s)
  Yoshimoto T, Xu M, Mizoguchi I, Chiba Y, Kamiya S, Matsui M, Shahrara S, Mizuguchi J
- Organizer
  The 8the GARN Meeting
- Place of Presentation
  Chiba, Japan
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production2011
- Author(s)
  Xu M, Morishima N, Mizoguchi I, Chiba Y, Fujita K, Kuroda M, Iwakura Y, Cua DJ, Yasutomo K, Mizuguchi J, Yoshimoto T
- Organizer
  第168回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-23590475

1. YOSHIMOTO Takayuki (80202406)

# of Collaborated Projects: 4 results

# of Collaborated Products: 47 results
2. SUDO Katsuko (50126091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 曲寧 (70527952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 隅山香織 (20433914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ISAKA Keiichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 溝口出

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
7. 大脇敏之

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
8. 西洋孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 黒田雅彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 河上裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Xu Mingli 徐 明利

XU Mingli 徐 明利

Research Projects

Research Products

Co-Researchers

脳卒中・脊髄損傷の後遺障害のリハビリテーション治療への漢方薬の応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive study on IL-27, one of the IL-12 family cytokines, aiming at its clinical application for cancer immunotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and functional analysis of a novel IL-6/IL-12 family cytokinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New mechanism whereby IL-23 regulates immune responses through Notch signallingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Induction of potent antitumor immunity by intradermal <scp>DNA</scp> injection using a novel needle‐free pyro‐drive jet injector2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 骨髄由来抑制細胞の分子機序2021

Author(s)

Journal Title

Data Source

[Journal Article] A chaperone-like role for EBI3 in collaboration with calnexin under inflammatory conditions.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IL-23p19 and CD5 antigen-like form a possible heterodimeric cytokine and contribute to experimental autoimmune encephalomyelitis development.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EBV-induced gene 3 augments IL-23Rα protein expression through a chaperone calnexin.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Worldwide consortium-based validation of Immunoscore for the classification of colon cancer.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective effects against tumors and infection by IL-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interleukin-27 exerts its antitumor effects by promoting differentiation of hematopoietic stem cells to M1 macrophages.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prediction of chemical respiratory and contact sensitizers by OX40L expression in dendritic cells using a novel 3D co-culture system.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expanding Diversity in Molecular Structures and Functions of the IL-6/IL-12 Heterodimeric Cytokine Family2016

Xu Mingli 徐明利

XU Mingli 徐明利

[Journal Article] サイトカインのすべて　IL-352012