Takatori Sho 高鳥翔

… Alternative Names

TAKATORI SHO 高鳥翔

高鳥翔タカトリシヨウ

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Researcher Number	80624361
Other IDs	https://orcid.org/0000-0002-3925-4011
Affiliation (Current)	2025: 東京大学, 大学院薬学系研究科(薬学部), 助教
Affiliation (based on the past Project Information) *help	2017 – 2024: 東京大学, 大学院薬学系研究科(薬学部), 助教 2017: 東京大学, 大学院薬学研究科, 助教 2014 – 2015: 東京大学, 薬学研究科(研究院), 助教 2012: 名古屋大学, 医学(系)研究科(研究院), その他
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy / General anatomy (including histology/embryology) / Cell biology Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields / General anatomy (including histology/embryology)
Keywords	Principal Investigator ミクログリア / アルツハイマー病 / ホスホイノシチド / 神経細胞死 / 貪食 / 細胞死 / ホスファチジルセリン / DAP12 / INPP5D / TYROBP … More / TREM2 / 電子顕微鏡 / 脂質 / 凍結割断レプリカ / 急速凍結法 / エンドサイトーシス … More Except Principal Investigator ストレス応答 / グリア細胞 / 神経変性 / 認知症 / 細胞連関 / 機能連関 / 電子顕微鏡 / リポファジー / 脂質ドメイン / 凍結割断レプリカ法 / 肝細胞 / 核膜 / オートファジー / 脂肪滴 / 膜脂質 Less

中枢神経系プロテイノパチー発症機構の統合的解明
- Principal Investigator
  
  富田泰輔
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
アルツハイマー病神経変性過程におけるミクログリアによる神経食作用の病的意義解明Principal Investigator
- Principal Investigator
  
  高鳥翔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  The University of Tokyo
Elucidation of the pathological roles of phosphoinositide signaling in microgliaPrincipal Investigator
- Principal Investigator
  
  Takatori Sho
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
Elucidation of Cellular Pathogenesis as a Key Mechanism for Neurodegenerative Processes in the Pathogenesis of Dementia
- Principal Investigator
  
  Tomita Taisuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
Involvement of microglial lipid signaling in the pathomechanism of Alzheimer diseasePrincipal Investigator
- Principal Investigator
  
  Takatori Sho
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Cell biological studies on membrane lipid distribution and dynamics
- Principal Investigator
  
  Fujimoto Toyoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Nagoya University
Visualization of the phosphoinositide localization during endocytosisPrincipal Investigator
- Principal Investigator
  
  Takatori Sho
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  The University of Tokyo
ファージ提示型単鎖抗体と化合物ライブラリを応用した脂質標識プローブの系統的探索Principal Investigator
- Principal Investigator
  
  高鳥翔
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book Patent Other

[Book] 医学のあゆみ274巻12号2020
- Author(s)
  竹本亮太、高鳥翔、富田泰輔
- Total Pages
  2
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-19H01015
[Journal Article] Protocol for gene knockdown using siRNA in primary cultured neonatal murine microglia2024
- Author(s)
  Kato Yuma、Takatori Sho、Akahori Aika、Etani Hayato、Chu Yung Ning、Tomita Taisuke
- Journal Title
  
  STAR Protocols
  
  Volume: 5 Issue: 1 Pages: 102867-102867
- DOI
  10.1016/j.xpro.2024.102867
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07344, KAKENHI-PROJECT-23H00394
[Journal Article] Molecular basis promoting centriole triplet microtubule assembly2024
- Author(s)
  Takeda Yutaka、Chinen Takumi、Honda Shunnosuke、Takatori Sho、Okuda Shotaro、Yamamoto Shohei、Fukuyama Masamitsu、Takeuchi Koh、Tomita Taisuke、Hata Shoji、Kitagawa Daiju
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 2216-2216
- DOI
  10.1038/s41467-024-46454-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18374, KAKENHI-PROJECT-22K19305, KAKENHI-PROJECT-22KJ0636, KAKENHI-PROJECT-23K23892, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23H00394
[Journal Article] アルツハイマー病におけるミクログリア変化と病的役割2023
- Author(s)
  赤堀愛果、高鳥翔、富田泰輔
- Volume
  14
- Pages
  3115
- DOI
  10.18958/7381-00001-0001089-00
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-22K07344
[Journal Article] Pathological Roles of INPP5D in Alzheimer’s Disease2023
- Author(s)
  Chu Yung Ning、Akahori Aika、Takatori Sho、Tomita Taisuke
- Journal Title
  
  Advances in Experimental Medicine and Biology
  
  Volume: 1423 Pages: 289-301
- DOI
  10.1007/978-3-031-31978-5_30
- ISBN
  9783031319778, 9783031319785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07344, KAKENHI-PROJECT-23H00394
[Journal Article] TOLLIP acts as a cargo adaptor to promote lysosomal degradation of aberrant ER membrane proteins2023
- Author(s)
  Hayashi Yuki、Takatori Sho、Warsame Waleed Y、Tomita Taisuke、Fujisawa Takao、Ichijo Hidenori
- Journal Title
  
  The EMBO Journal
  
  Volume: 42 Issue: 23
- DOI
  10.15252/embj.2023114272
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14143, KAKENHI-PROJECT-22K06610, KAKENHI-PUBLICLY-22H04636, KAKENHI-PUBLICLY-22H04804, KAKENHI-PROJECT-21H04760, KAKENHI-PROJECT-23H00394
[Journal Article] GPR120 signaling controls amyloid-β degrading activity of matrix metalloproteinases2021
- Author(s)
  Kazunori Kikuchi, Takuya Tatebe, Yuki Sudo, Miyabishara Yokoyama, Kiwami Kidana, Yung Wen Chiu, Sho Takatori, Makoto Arita, Yukiko Hori, Taisuke Tomita
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 41(28) Issue: 28 Pages: 6173-6185
- DOI
  10.1523/jneurosci.2595-20.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07080, KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-23K21357
[Journal Article] Photo-oxygenation by a biocompatible catalyst reduces amyloid-β levels in the brains of Alzheimer’s disease model mice2021
- Author(s)
  Ozawa S, Hori Y, Shimizu Y, Taniguchi A, Suzuki T, Wang W, Chiu YW, Koike R, Yokoshima S, Fukuyama T, Takatori S, Sohma Y, Kanai M, Tomita T
- Journal Title
  
  Brain
  
  Volume: - Issue: 6 Pages: 1884-1897
- DOI
  10.1093/brain/awab058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06653, KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19K07080, KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-20H00489
[Journal Article] Dietary cis-9, trans-11-conjugated linoleic acid reduces amyloid β-protein accumulation and upregulates anti-inflammatory cytokines in an Alzheimer's disease mouse model2021
- Author(s)
  Yu Fujita, Kuniyuki Kano, Shigenobu Kishino, Toshihiro Nagao, Xuefeng Shen, Chiharu Sato, Hatsune Hatakeyama, Yume Ota, Sho Niibori, Ayako Nomura, Kota Kikuchi, Wataru Yasuno, Sho Takatori, Kazunori Kikuchi, Yoshitake Sano, Taisuke Tomita, Toshiharu Suzuki, Junken Aoki, Kun Zou, Shunji Natori, Hiroto Komano
- Journal Title
  
  Scientific Reports
  
  Volume: 11(1) Issue: 1 Pages: 9749-9749
- DOI
  10.1038/s41598-021-88870-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07080, KAKENHI-PROJECT-19H01015
[Journal Article] BORCS6 is involved in the enlargement of lung lamellar bodies in Lrrk2 knockout mice2021
- Author(s)
  Miho Araki, Sho Takatori, Genta Ito, Taisuke Tomita
- Journal Title
  
  BioRxiv
  
  Volume: －
- DOI
  10.1101/2021.03.05.434068
- Open Access
- Data Source
  KAKENHI-PROJECT-19K07080
[Journal Article] ABCトランスポーターとAlzheimer病2019
- Author(s)
  王文博、高鳥翔、富田泰輔
- Journal Title
  
  医学のあゆみ
  
  Volume: 271(1) Pages: 11-16
- Data Source
  KAKENHI-PROJECT-19K07080
[Journal Article] Genetic Risk Factors for Alzheimer Disease: Emerging Roles of Microglia in Disease Pathomechanisms2019
- Author(s)
  Takatori Sho、Wang Wenbo、Iguchi Akihiro、Tomita Taisuke
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 1118 Pages: 83-116
- DOI
  10.1007/978-3-030-05542-4_5
- ISBN
  9783030055417, 9783030055424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02492, KAKENHI-PROJECT-17K15446, KAKENHI-PROJECT-19H01015
[Journal Article] Definition of phosphoinositide distribution in the nanoscale2019
- Author(s)
  Tsuji Takuma、Takatori Sho、Fujimoto Toyoshi
- Journal Title
  
  Current Opinion in Cell Biology
  
  Volume: 57 Pages: 33-39
- DOI
  10.1016/j.ceb.2018.10.008
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05902, KAKENHI-PROJECT-17K15446, KAKENHI-PROJECT-17K15544
[Journal Article] Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer’s disease model mice2018
- Author(s)
  Kidana K, Tatebe T, Ito K, Hara N, Kakita A, Saito T, Takatori S, Ouchi Y, Ikeuchi T, Makino M, Saido TC, Akishita M, Iwatsubo T, Hori Y, Tomita T
- Journal Title
  
  EMBO Molecular Medicine
  
  Volume: 10 Issue: 3
- DOI
  10.15252/emmm.201708184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15446, KAKENHI-PROJECT-15H02492, KAKENHI-PROJECT-15H04800, KAKENHI-PROJECT-16K18871
[Journal Article] AP180 N-Terminal Homology (ANTH) and Epsin N-Terminal Homology (ENTH) Domains: Physiological Functions and Involvement in Disease2018
- Author(s)
  Takatori Sho、Tomita Taisuke
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: in press Pages: 1-22
- DOI
  10.1007/5584_2018_218
- ISBN
  9783030143381, 9783030143398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02492, KAKENHI-PROJECT-17K15446
[Journal Article] Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole2017
- Author(s)
  Tsuji T, Fujimoto M, Tatematsu T, Cheng J, Orii M, Takatori S, Fujimoto T
- Journal Title
  
  eLife
  
  Volume: 6
- DOI
  10.7554/elife.25960
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15446, KAKENHI-PROJECT-17K15544, KAKENHI-PROJECT-15H02500, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05902
[Journal Article] A New Electron Microscopic Method to Observe the Distribution of Phosphatidylinositol 3,4-bisphosphate2017
- Author(s)
  Aktar S, Takatori S, Tsuji T, Orii M, Ohsaki Y, Cheng J, Fujimoto T
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 50 Issue: 5 Pages: 141-147
- DOI
  10.1267/ahc.17025
- NAID
  130006179489
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15446, KAKENHI-PROJECT-17K15544, KAKENHI-PROJECT-15H02500, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05902, KAKENHI-PROJECT-15K08152
[Journal Article] Partial loss of CALM function reduces Abeta42 production and amyloid deposition in vivo2016
- Author(s)
  Kanatsu K, Hori Y, Takatori S, Watanabe T, Iwatsubo T, Tomita T
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860132
[Journal Article] A novel imaging method revealed phosphatidylinositol 3,5-bisphosphate-rich domains in the endosome/lysosome membrane2016
- Author(s)
  Takatori S, Fujimoto T
- Journal Title
  
  Commun Integr Biol
  
  Volume: 9 Issue: 2 Pages: e1145319-e1145319
- DOI
  10.1080/19420889.2016.1145319
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-26860132
[Journal Article] Phosphatidylinositol 3,5-bisphosphate-rich membrane domains in endosomes and lysosomes2016
- Author(s)
  Takatori S, Tatematsu T, Cheng J, Matsumoto J, Akano T, Fujimoto T
- Journal Title
  
  Traffic
  
  Volume: 17 Issue: 2 Pages: 154-167
- DOI
  10.1111/tra.12346
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05902, KAKENHI-PUBLICLY-26111510, KAKENHI-PROJECT-26860132
[Journal Article] Microscopy of membrane lipids: how precisely can we define their distribution?2015
- Author(s)
  Takatori S and Fujimoto T
- Journal Title
  
  Essays Biochem.
  
  Volume: 57 Pages: 81-91
- DOI
  10.1042/bse0570081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10940, KAKENHI-PROJECT-24390045, KAKENHI-PROJECT-26860132, KAKENHI-ORGANIZER-15H05897
[Journal Article] Asymmetrical distribution of choline phospholipids revealed by click chemistry and freeze-fracture electron microscopy.2014
- Author(s)
  Iyoshi S, Cheng J, Tatematsu T, Takatori S, Taki M, Yamamoto Y, Salic A and Fujimoto T
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 9(10) Issue: 10 Pages: 2217-2222
- DOI
  10.1021/cb500558n
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10940, KAKENHI-PROJECT-24390045, KAKENHI-PROJECT-26860132
[Patent] 自閉症発症機構に関連する接着分子2019
- Inventor(s)
  富田泰輔、伊藤弦太、高鳥翔、長友亮太、吉田文明
- Industrial Property Rights Holder
  富田泰輔、伊藤弦太、高鳥翔、長友亮太、吉田文明
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17K15446
[Presentation] アルツハイマー病におけるAβ・タウ蓄積を模倣した新規マウスモデルの確立と遺伝学的危険因子への介入研究2023
- Author(s)
  赤堀愛果、高鳥翔、富田泰輔
- Organizer
  タウ研究会
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] GPR34選択的アゴニストはミクログリアにおけるアミロイドβ線維の貪食を促進する2023
- Author(s)
  惠谷隼、高鳥翔、近江純平、青木淳賢、大和田智彦、渡部博貴、岡野栄之、富田泰輔
- Organizer
  第96回日本生化学大会
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] 繊毛病タンパク質HYLS1による中心小体三連微小管構造の形成促進メカニズム2023
- Author(s)
  竹田穣、知念拓実、本田俊之介、高鳥翔、奥田祥太郎、富田泰輔、畠星治、北川大樹
- Organizer
  第96回日本生化学大会
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] 自閉症モデルマウスにおけるシナプス形成異常関連分子Lingo2の代謝機構解析2023
- Author(s)
  富田泰輔、吉田文明、熊詩若、高鳥翔、伊藤弦太
- Organizer
  第28回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] アルツハイマー病治療標的としてのミクログリア生存性回復因子の網羅的探索2023
- Author(s)
  加藤由真、高鳥翔、富田泰輔
- Organizer
  BIOUT
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] Elucidating the Pathological Roles of INPP5D in Alzheimer Disease2023
- Author(s)
  Takatori S, Iguchi A, Ito G, Hori Y, Sasaki J, Saito T, Saido TC, Ikezu T, Takai T, Sasaki T, Tomita T
- Organizer
  Neuroscience 2023 (Society for Neuroscience)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07344
[Presentation] ミクログリアによるアミロイドβ貪食の分子機構とその制御2023
- Author(s)
  高鳥翔、惠谷隼、近江純平、斉藤貴志、西道隆臣、高井俊行、大和田智彦、青木淳賢、富田泰輔
- Organizer
  第42回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] 迅速かつ簡便にtau凝集を誘導できるタウオパチーモデルマウスの樹立2023
- Author(s)
  巽理紗、高鳥翔、木村妙子、富田泰輔
- Organizer
  第96回日本生化学大会
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] ミクログリアによるアミロイドβ貪食の分子機構とその制御2023
- Author(s)
  高鳥翔, 惠谷隼, 近江純平, 斉藤貴志, 西道隆臣, 高井俊行, 大和田智彦, 青木淳賢, 富田泰輔
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07344
[Presentation] Alzheimer disease resilience factor RAB10 regulates extracellular tau uptake and inflammatory responses in microglia.2023
- Author(s)
  Kai Wang, Shot Takatori, Taisuke Tomita
- Organizer
  Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] The role of two AD risk gene, TREM2 and INPP5D, in fibrillar Amyloid-β uptake in microglia2023
- Author(s)
  惠谷隼、王文博、高鳥翔、井口明優、富田泰輔
- Organizer
  BIOUT
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] 繊毛病関連タンパク質HYLS1による中心小体微小管の高次構造化2023
- Author(s)
  竹田穣、知念拓実、本田俊之介、高鳥翔、富田泰輔、畠星治、北川大樹
- Organizer
  BIOUT
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] AAV-PHP.eB 発現系を用いたタウオパチーモデルマウスの作製2023
- Author(s)
  巽理紗、高鳥翔、木村妙子、富田泰輔
- Organizer
  2023年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] Pathological roles of microglial phosphatase INPP5D in Alzheimer disease2023
- Author(s)
  Chu Yung-Ning、井口明優、高鳥翔、富田泰輔
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] 加齢とともに凝集するタンパク質の探索とその生理的意義の解明2023
- Author(s)
  渡邊綾香、平山尚志郎、小湊樹、高鳥翔、Varela Juan A.、富田泰輔、村田茂穂
- Organizer
  第96回日本生化学大会
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] Elucidating the Pathological Roles of INPP5D in Alzheimer Disease.2023
- Author(s)
  Sho Takatori, Akihiro Iguchi, Genta Ito, Yukiko Hori, Junko Sasaki, Takashi Saito, Takaomi C Saido, Tsuneya Ikezu, Toshiyuki Takai, Takehiko Sasaki, Taisuke Tomita
- Organizer
  Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] Molecular mechanisms of the microglial response to amyloid β2023
- Author(s)
  Sho Takatori, Wenbo Wang, Akihiro Iguchi, Hayato Etani, Yung-Ning Chu, Aika Akahori, Junko Sasaki, Takashi Saito, Takaomi Saido, Tsuneya Ikezu, Toshiyuki Takai, Takehiko Sasaki, Taisuke Tomita
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-22K07344
[Presentation] 加齢依存的に凝集するタンパク質の探索とその生理的意義の解明2023
- Author(s)
  渡邊綾香、平山尚志郎、小湊樹、高鳥翔、Varela Juan A.、富田泰輔、村田茂穂
- Organizer
  BIOUT
- Data Source
  KAKENHI-PROJECT-23H00394
[Presentation] Elucidation of pathological roles of INPP5D in Alzheimer disease2022
- Author(s)
  高鳥翔、井口明優、木村新伍、堀由起子、佐々木純子、斉藤貴志、西道隆臣、池津庸哉、高井俊行、佐々木雄彦、富田泰輔
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] ミクログリアにおけるTREM2機能新規制御因子の探索と同定2022
- Author(s)
  加藤由真、王文博、高鳥翔、富田泰輔
- Organizer
  第44回神経組織培養研究会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Inhibition of NF-κB pathway in the astrocytes facilitates the proteolytic clearance of amyloid-β by kallikrein-related peptidase 72022
- Author(s)
  Taisuke Tomita, Yuki Sudo, Kazunori Kikuchi, Chia Jen Sung, Sho Takatori, Yukiko Hori
- Organizer
  Neuroscience 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] ミクログリアによるAmyloid-β凝集体貪食機構の解明2022
- Author(s)
  惠谷隼、王文博、高鳥翔、井口明優、富田泰輔
- Organizer
  第２１回次世代を担う若手のためのファーマ・バイオフォーラム2022
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Alzheimer disease resilience factor RAB10 regulates tau uptake in microglia2022
- Author(s)
  Kai Wang、高鳥翔、富田泰輔
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Pathological roles of microglial gene INPP5D in a mouse model of Alzheimer disease.2022
- Author(s)
  Sho Takatori, Akihiro Iguchi, Shingo Kimura, Hiroki Muneto, Kai Wang, Hayato Etani, Yukiko Hori, Junko Sasaki, Takashi Saito, Takaomi C Saido, Tsuneya Ikezu, Toshiyuki Takai, Takehiko Sasaki, Taisuke Tomita
- Organizer
  ISMND2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] INPP5D modulates TREM2 loss-of-function phenotypes in a mouse model of Alzheimer disease.2022
- Author(s)
  Akihiro Iguchi, Sho Takatori, Shingo Kimura, Yukiko Hori, Junko Sasaki, Takashi Saito, Takaomi C Saido, Tsuneya Ikezu, Toshiyuki Takai, Takehiko Sasaki, Taisuke Tomita
- Organizer
  CINF2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Alzheimer disease risk factor TREM2 and INPP5D oppositely regulate microglial uptake of Amyloid beta fibrils2022
- Author(s)
  Hayato Etani, Sho Takatori, Taisuke Tomita
- Organizer
  第26回グリア研究会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] INPP5D haplodeficiency rescued TREM2-loss-of-function phenotype of microglia in Alzheimer disease model mice.2021
- Author(s)
  Akihiro Iguchi, Sho Takatori, Shingo Kimura, Yukiko Hori, Junko Sasaki, Takashi Saito, Sakaomi C. Saido, Tsuneya Ikezu, Toshiyuki Takai, Takehiko Sasaki, Taisuke Tomita
- Organizer
  New Horizons in Alzheimer's Disease (Hybrid edition)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] 自閉症モデルマウスにおけるシナプス形成異常関連分子Lingo2の代謝機構解析2021
- Author(s)
  熊詩若、吉田文明、伊藤弦太、高鳥翔、富田泰輔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] ミクログリアによるタウ線維の取込みと分泌の分子機構に関する研究2021
- Author(s)
  竹本亮太、高鳥翔、富田泰輔
- Organizer
  第40回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] アストロサイト由来Aβ分解酵素Kallikrein-related peptidase 7はNMDA受容体及びNF-κB経路によって発現が制御される2021
- Author(s)
  須藤優喜、木棚究、建部卓也、菊池一徳、堀由起子、高鳥翔、富田泰輔
- Organizer
  第40回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] アルツハイマー病治療標的としてのミクログリア生存性回復因子の探索2021
- Author(s)
  加藤由真、高鳥翔、富田泰輔
- Organizer
  第40回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] BORCS6はLrrk2ノックアウトマウスにおける層板小体肥大化に関与する2021
- Author(s)
  荒木美保、伊藤恭平、高鳥翔、伊藤弦太、富田泰輔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] ミクログリアによるアミロイドβ線維貪食機構の解明2020
- Author(s)
  王文博、高鳥翔、富田泰輔
- Organizer
  第39回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Elucidation of molecular mechanism that induce abnormal excitatory synapse formation in valproic acid-induced rodent model of autism spectrum disorders2020
- Author(s)
  Fumiaki Yoshida, Ryota Nagatomo, Misaki Kimura, Genta Ito, Sho Takatori, Taisuke Tomita
- Organizer
  BIOUT
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Phospholipase C gamma 2 regulates ApoE secretion in microglia2020
- Author(s)
  宗藤大樹, 高鳥翔, 富田泰輔
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07080
[Presentation] マイクログリアによる光酸素化Aβ代謝促進機構の解明2020
- Author(s)
  小澤柊太、谷口敦彦、清水裕介、王文博、横島聡、福山透、高鳥翔、相馬洋平、金井求、堀由起子、富田泰輔
- Organizer
  第39回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] INPP5D modulates Trem2-loss-of-function phenotype of AD model mice2020
- Author(s)
  井口明優, 高鳥翔, 木村新伍, 佐々木純子, 斉藤貴志, 西道隆臣, 高井俊行, 佐々木雄彦, 富田泰輔
- Organizer
  第20回東京大学生命科学シンポジウム BIO UT
- Data Source
  KAKENHI-PROJECT-19K07080
[Presentation] INPP5D modulates Trem2-loss-of-function phenotype of AD model mice2020
- Author(s)
  井口明優、高鳥翔、木村新伍、佐々木純子、斉藤貴志、西道隆臣、高井俊行、佐々木雄彦、富田泰輔
- Organizer
  BIOUT
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] アルツハイマー病遺伝学的リスク因子INPP5Dの病態関与に関する研究2019
- Author(s)
  高鳥翔、井口明優、木村新伍、佐々木純子、佐々木雄彦、高井俊行、斉藤貴志、西道隆臣、富田泰輔
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Elucidation of molecular mechanism that induce abnormal excitatory synapse formation in valproic acid-induced rodent model of autism spectrum disorders.2019
- Author(s)
  Fumiaki Yoshida, Ryota Nagatomo, Misaki Kimura, Genta Ito, Sho Takatori, Taisuke Tomita
- Organizer
  Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Proteomic analysis of lamellar bodies in Lrrk2 knockout mice.2019
- Author(s)
  Miho Araki, Sho Takatori, Genta Ito, Taisuke Tomita
- Organizer
  Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] ミクログリアによるアミロイドβの認識・応答とその分子機構2019
- Author(s)
  高鳥翔、井口明優、木村新伍、佐々木純子、佐々木雄彦、高井俊行、斉藤貴志、西道隆臣、富田泰輔
- Organizer
  Neuro2019
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] バルプロ酸母体投与自閉症モデルマウスにおいて興奮性シナプス形成異常をもたらす分子メカニズムの解明2019
- Author(s)
  吉田文明、長友亮太、木村美咲、伊藤弦太、高鳥翔、富田泰輔
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] アルツハイマー病リスク遺伝子INPP5DとTREM2シグナルの相互作用解析2019
- Author(s)
  井口明優、高鳥翔、木村新伍、佐々木純子、斉藤貴志、西道隆臣、高井俊行、佐々木雄彦、富田泰輔
- Organizer
  BIOUT
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] アルツハイマー病リスク遺伝子INPP5DがTREM2シグナル伝達において果たす役割の解明2019
- Author(s)
  井口明優、高鳥翔、木村新伍、佐々木純子、斉藤貴志、西道隆臣、高井俊行、佐々木雄彦、富田泰輔
- Organizer
  第38回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] 層板小体の恒常性維持におけるLRRK2の役割2019
- Author(s)
  伊藤弦太、荒木美保、高鳥翔、富田泰輔
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Expression of kallikrein-related peptidase 7, an astrocyte-derived novel amyloid-β degrading protease, is negatively regulated by NMDA receptor and NF-κB signaling pathways.2019
- Author(s)
  Yuki Sudo, Kiwami Kidana, Takuya Tatebe, Yukiko Hori, Sho Takatori, Taisuke Tomita
- Organizer
  IPS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Transcriptional regulation of kallikrein-related peptidase 7, an astrocyte-derived amyloid-β degrading protease, in the pathogenesis of Alzheimer disease.2019
- Author(s)
  Taisuke Tomita, Yuki Sudo, Kiwami Kidana, Takuya Tatebe, Sho Takatori, Yukiko Hori
- Organizer
  IPS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] アストロサイト由来Aβ分解酵素Kallikrein-related peptidase 7の発現制御機構の解析2019
- Author(s)
  須藤優喜、木棚究、建部卓也、堀由起子、高鳥翔、富田泰輔
- Organizer
  BIOUT
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] アルツハイマー病リスク因子TREM2/DAP12と相互作用するタンパク質の解明2019
- Author(s)
  木村新伍、高鳥翔、井口明優、荒木美保、伊藤弦太、富田泰輔
- Organizer
  第38回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19H01015
[Presentation] Molecular mechanisms of microglial recognition and response to amyloid β2019
- Author(s)
  高鳥翔、井口明優、木村新伍、佐々木純子、佐々木雄彦、高井俊行、斉藤貴志、西道隆臣、富田泰輔
- Organizer
  Neuro2019
- Data Source
  KAKENHI-PROJECT-19K07080
[Presentation] アルツハイマー病リスク遺伝子RIN3のミクログリアにおける病的機能の解明2018
- Author(s)
  藤田隆弘, 王文博, 高鳥翔, 富田泰輔
- Organizer
  第40回神経組織培養研究会
- Data Source
  KAKENHI-PROJECT-17K15446
[Presentation] 層板小体の恒常性維持におけるLRRK2の役割2018
- Author(s)
  荒木美保, 高鳥翔, 伊藤弦太, 富田泰輔
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K15446
[Presentation] バルプロ酸母体投与自閉症モデルマウスにおいて興奮性シナプス形成異常をもたらす分子メカニズムの解明2018
- Author(s)
  吉田文明, 長友亮太, 木村美咲, 伊藤弦太, 高鳥翔, 富田泰輔
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K15446
[Presentation] アルツハイマー病リスク遺伝子INPP5Dの病理学的役割の解明2018
- Author(s)
  井口明優, 高鳥翔, 木村新伍, 佐々木純子, 斉藤貴志, 西道隆臣, 高井俊行, 佐々木雄彦, 富田泰輔
- Organizer
  第40回神経組織培養研究会
- Data Source
  KAKENHI-PROJECT-17K15446
[Presentation] Analysis of the effects of INPP5D/SHIP1 deficiency on amyloid pathology in Alzheimer model mice2017
- Author(s)
  Takatori S
- Organizer
  EMBO/EMBL Symposium: Mechanisms of Neurodegeneration
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15446
[Presentation] Heterogenous distribution of phospholipids in the membrane revealed by quick-freezing and freeze-fracture replica labeling2015
- Author(s)
  高鳥翔, 立松律弥子, 松本惇, 赤野琢也, 程晶磊, Aktar Sharmin, 藤本豊士
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860132
[]
[]

1. Tomita Taisuke (30292957)

# of Collaborated Projects: 2 results

# of Collaborated Products: 48 results
2. 堀由起子 (80610683)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. Fujimoto Toyoshi (50115929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. YAMAMOTO HAYASHI (80551283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAGUCHI TOMOHIKO (10300881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 大崎雄樹 (00378027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 辻琢磨 (40725628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 伊藤弦太 (10431892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
9. 樽谷愛理 (10815187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 木村妙子 (60748820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 竹内恒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 林裕輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takatori Sho 高鳥 翔

TAKATORI SHO 高鳥 翔

高鳥 翔 タカトリ シヨウ

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中枢神経系プロテイノパチー発症機構の統合的解明

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アルツハイマー病神経変性過程におけるミクログリアによる神経食作用の病的意義解明Principal Investigator

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Elucidation of the pathological roles of phosphoinositide signaling in microgliaPrincipal Investigator

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Elucidation of Cellular Pathogenesis as a Key Mechanism for Neurodegenerative Processes in the Pathogenesis of Dementia

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Involvement of microglial lipid signaling in the pathomechanism of Alzheimer diseasePrincipal Investigator

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Cell biological studies on membrane lipid distribution and dynamics

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Visualization of the phosphoinositide localization during endocytosisPrincipal Investigator

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ファージ提示型単鎖抗体と化合物ライブラリを応用した脂質標識プローブの系統的探索Principal Investigator

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[Book] 医学のあゆみ274巻12号2020

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[Journal Article] Protocol for gene knockdown using siRNA in primary cultured neonatal murine microglia2024

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[Journal Article] Molecular basis promoting centriole triplet microtubule assembly2024

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[Journal Article] アルツハイマー病におけるミクログリア変化と病的役割2023

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[Journal Article] Pathological Roles of INPP5D in Alzheimer’s Disease2023

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Takatori Sho 高鳥翔

TAKATORI SHO 高鳥翔

高鳥翔タカトリシヨウ