TOYODA Yu 豊田優

Researcher Number	80650340
Other IDs
Affiliation (Current)	2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 分子生体制御学, 講師 2025: 東京大学, 医学部附属病院, 届出研究員
Affiliation (based on the past Project Information) *help	2021 – 2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 分子生体制御学, 講師 2020 – 2023: 東京大学, 医学部附属病院, 届出研究員 2020 – 2021: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 分子生体制御学, 助教 2020: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 医学教育部医学科, 助教 2017 – 2019: 東京大学, 医学部附属病院, 特任研究員 … More 2015 – 2016: 東京大学, 医学部附属病院, 特任助教 2015: 東京大学, 医学部附属病院, 助教 2014: 東京大学, 医学部附属病院, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 47060:Clinical pharmacy-related / Health science and related fields / Applied anthropology / General surgery Except Principal Investigator Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 59040:Nutrition science and health science-related / Basic Section 56050:Otorhinolaryngology-related / Medical pharmacy / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Medium-sized Section 47:Pharmaceutical sciences and related fields / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Otorhinolaryngology
Keywords	Principal Investigator 体質 / トランスポーター / 健康科学 / 栄養 / トランスレーショナルリサーチ / トランスレーショナル研究 / 膜輸送体 / 腋臭症 / 個人差 / 尿酸 … More / ドラッグリポジショニング / 生理活性 / 食品 / 栄養学 / 嗜好性飲料 / 脂肪肝 / 体臭発生機序の分子実体 / 体質・健康 / 健康 / 乳腺外科学 / 乳がんリスク因子 / メタボローム解析 / 乳がん … More Except Principal Investigator トランスポーター / 国際共同研究 / 尿酸 / 耳垢 / 中耳真珠腫 / 胆汁排泄 / 高尿酸血症 / 痛風 / 消化管吸収 / 脂質トランスポーター / 外耳pH / 細菌叢 / 外耳道内pH環境 / 外耳道内ｐH環境 / 外耳道アポクリン腺 / ABCC11遺伝子多型 / 生理学 / 血液型 / 動脈硬化症 / 尿酸値 / マーカー / 神経変性疾患 / 慢性腎臓病 / 脳 / 栄養学 / ビタミン / GWAS / CDMRV仮説 / サブタイプゲノムワイド関連解析 / ゲノム個別化看護・予防 / ゲノム個別化医療・予防 / 分子遺伝疫学的解析 / 痛風遺伝子 / 尿酸輸送体 / 低尿酸血症 / ゲノム個別化栄養指導 / ゲノム個別化看護 / ゲノム個別化予防 / トランスレーショナルリサーチ / 非アルコール性脂肪性肝疾患 / 人種差 / 遺伝子多型 / ABCC11 遺伝子 / 中耳pH / 湿性耳垢 / 耳垢pH / ABCC11 遺伝子多型 / 薬物動態学 / 薬理学 / 脂質 / ABCC11遺伝子 / ABCC11 / 外耳環境 / ABCC 遺伝子 / 胆管側膜輸送体 Less

新規排出型尿酸輸送体の探索・同定、健康体質に与える影響の分子生理学的理解と制御Principal Investigator
- Principal Investigator
  
  豊田優
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Defense Medical College
Molecular epidemiological research of uric acid levels and their determinants as markers of chronic kidney disease and neurodegenerative diseases
- Principal Investigator
  
  中山昌喜
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  National Defense Medical College
食事由来脂質の吸収／排泄バランスの定量的理解と生活習慣病克服への応用
- Principal Investigator
  
  山梨義英
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  The University of Tokyo
稀な血液型における生活習慣病リスクの証明：判定方法の正確性向上と予防医学への挑戦
- Principal Investigator
  
  松尾洋孝
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  National Defense Medical College
An international (Japan-USA-Vietnam) collaborative research for molecular genetic epidemiology in urate-related diseases including gout and hyperuricemia
- Principal Investigator
  
  松尾洋孝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  National Defense Medical College
Vitamin C research based on vitamin C transporters
- Principal Investigator
  
  Takada Tappei
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
Earwax determination gene ABCC11 polymorphism related to flora in the ear wax and risk of developing middle ear cholesteatoma
- Principal Investigator
  
  楠威志
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Juntendo University
International collaborative study on the genetic factors that regulate serum urate levels in humans: clinico-genetic analyses and functional studies focusing on urate transporters
- Principal Investigator
  
  Matsuo Hirotaka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  National Defense Medical College
新規尿酸輸送体の遺伝的背景の違いが健康体質に与える影響の分子生理学的理解と制御Principal Investigator
- Principal Investigator
  
  豊田優
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Defense Medical College
Understanding the biological defense system by absorption/excretion balance of dietary lipids and its application to disease treatment
- Principal Investigator
  
  Yamanashi Yoshihide
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  The University of Tokyo
Molecular and epidemiological research on gout and hyperuricemia from Japan: heading toward novel genome-personalized prevention and medicine
- Principal Investigator
  
  Matsuo Hirotaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  National Defense Medical College
Exploring of inhibitors for axillary osmidrosis risk factor and its physiological rolePrincipal Investigator
- Principal Investigator
  
  Toyoda Yu
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  National Defense Medical College
  The University of Tokyo
pHin the external or mddle ear related a risk factor of middle ear cholesteatoma
- Principal Investigator
  
  Kusunoki Takeshi
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Juntendo University
International collaboration on the research of novel urate transporters by leveraging genetic differences between the Japanese and the Czech
- Principal Investigator
  
  TAKADA Tappei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  The University of Tokyo
Searching of hepatoprotective substances in health promotive beverages in terms of the pharmacokinetics and bioactivityPrincipal Investigator
- Principal Investigator
  
  Toyoda Yu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Health science and related fields
- Research Institution
  The University of Tokyo
Investigation of transport mechanisms of lipid and lipophilic drugs
- Principal Investigator
  
  TAKADA Tappei
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  The University of Tokyo
ABC transporter of outer and middle ear related to a risk factor of middle cholesteatoma
- Principal Investigator
  
  Kusunoki Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Research on the novel risk of breast cancer focusing of the regulation of endo/exogenous substances in mammary glandsPrincipal Investigator
- Principal Investigator
  
  Toyoda Yu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Research for molecular bases relating to the development of body odor from armpitsPrincipal Investigator
- Principal Investigator
  
  Toyoda Yu
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Applied anthropology
- Research Institution
  The University of Tokyo
Investigation of organic solvent-mediated carcinogenic mechanisms of bile duct cancer
- Principal Investigator
  
  TAKADA Tappei
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Book Patent Other

[Book] 膜（細胞膜トランスポーターによる尿酸・ビタミンCの体内動態制御）2024
- Author(s)
  宮田大資、豊田優、高田龍平
- Total Pages
  7
- Publisher
  日本膜学会
- Data Source
  KAKENHI-PROJECT-22K19369
[Book] 日本栄養・食糧学会誌（ビタミンCの体内動態制御機構の温故知新―ついに見出された哺乳類の排出型輸送体VCEP）2023
- Author(s)
  豊田優、宮田大資、高田龍平
- Total Pages
  6
- Publisher
  日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-22K19369
[Book] 実験医学（ビタミンCの脳移行経路の発見～哺乳類ではじめて見出されたビタミンC排出型輸送体VCEP）2022
- Author(s)
  高田龍平、宮田大資、豊田優、鈴木洋史
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22K19369
[Book] 生化学（GLUT12の生理的重要性―尿酸の体内動態制御および脳へのビタミンC供給の観点から）2022
- Author(s)
  豊田優、宮田大資、高田龍平
- Total Pages
  6
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-22K19369
[Book] 電気泳動（痛風病因としての尿酸トランスポーターABCG2の病態生理学的重要性とレアバリアント解析）2021
- Author(s)
  豊田優、高田龍平、松尾洋孝、市田公美、Blanka Stiburkova、鈴木洋史
- Publisher
  日本電気泳動学会
- Data Source
  KAKENHI-PROJECT-18KK0247
[Book] ABC Transporters -40 Years on (Human ABC transporter ABCC11: Looking back pioneers’ odyssey and creating a new path toward clinical application) (doi 10.1007/978-3-319-23476-2_12)2016
- Author(s)
  Toshihisa Ishikawa, and Yu Toyoda.
- Total Pages
  22
- Publisher
  Springer International Publishing
- Data Source
  KAKENHI-PROJECT-15K15470
[Book] ABC Transporters -40 Years on (Human ABC transporter ABCC11: Looking back pioneers’ odyssey and creating a new path toward clinical application) (doi 10.1007/978-3-319-23476-2_12)2016
- Author(s)
  Toshihisa Ishikawa, and Yu Toyoda.
- Total Pages
  22
- Publisher
  Springer International Publishing
- Data Source
  KAKENHI-PROJECT-15H05610
[Book] ビタミン（ビタミンK吸収輸送体の発見）2016
- Author(s)
  高田龍平、山梨義英、小西健太郎、山本武人、豊田優、増尾友佑、山本英明、鈴木洋史
- Total Pages
  2
- Publisher
  日本ビタミン学会
- Data Source
  KAKENHI-PROJECT-16K15155
[Book] くすりと糖尿病（新規機序の薬物相互作用：ビタミンの体内動態の重要性）2016
- Author(s)
  高田龍平、山梨義英、山本武人、豊田優、山本英明、田中悠介、小峰瞳子、鈴木洋史
- Total Pages
  3
- Publisher
  日本くすりと糖尿病学会
- Data Source
  KAKENHI-PROJECT-16K15155
[Book] 第１３５年会講演ハイライト2015
- Author(s)
  豊田優
- Total Pages
  1
- Publisher
  日本薬学会
- Data Source
  KAKENHI-PROJECT-26670073
[Journal Article] Membrane Transporter (s)–mediated Regulation of Urate and Vitamin C Behavior in the Body2024
- Author(s)
  Miyata Hiroshi、Toyoda Yu、Takada Tappei
- Journal Title
  
  MEMBRANE
  
  Volume: 49 Issue: 2 Pages: 70-76
- DOI
  10.5360/membrane.49.70
- ISSN
  0385-1036, 1884-6440
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15293, KAKENHI-PROJECT-23K21618
[Journal Article] Biochemical characterization of Jr(a-) blood type-related ABCG2 variants: Arg147Trp and Ser572Arg disrupt the plasma membrane localization of ABCG2.2024
- Author(s)
  Toyoda Y, Matsuo H, Tanaka M, Stiburkova B, Takada T.
- Journal Title
  
  Transfusion
  
  Volume: 64 Issue: 2 Pages: 412-414
- DOI
  10.1111/trf.17625
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0152, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-23K21618
[Journal Article] 第5土曜特集遺伝統計学の新潮流--新規創薬･個別化医療への挑戦遺伝統計学と疾患オミクス研究痛風･高尿酸血症の大規模ゲノム解析2024
- Author(s)
  豊田優、竹花奈々、三浦美千瑠、松尾洋孝
- Journal Title
  
  医学のあゆみ
  
  Volume: 288 Issue: 13 Pages: 1111-1118
- DOI
  10.32118/ayu288131111
- ISSN
  0039-2359
- Year and Date
  2024-03-30
- Data Source
  KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-23K21618
[Journal Article] Dysuricemia.2023
- Author(s)
  Nakayama A, Kurajoh M, Toyoda Y, Takada T, Ichida K, Matsuo H.
- Journal Title
  
  Biomedicines
  
  Volume: 11 Issue: 12 Pages: 3169-3169
- DOI
  10.3390/biomedicines11123169
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0152, KAKENHI-PROJECT-21KK0173, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-23K21618
[Journal Article] Recent Advances in Research on Vitamin C Transporters2023
- Author(s)
  Toyoda Yu、Miyata Hiroshi、Takada Tappei
- Journal Title
  
  Nippon Eiyo Shokuryo Gakkaishi
  
  Volume: 76 Issue: 4 Pages: 193-198
- DOI
  10.4327/jsnfs.76.193
- ISSN
  0287-3516, 1883-2849
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15293, KAKENHI-PROJECT-23K21618
[Journal Article] SVCT2/SLC23A2 is a sodium-dependent urate transporter: functional properties and practical application.2023
- Author(s)
  Toyoda Y, Miyata H, Shigesawa R, Matsuo H, Suzuki H, Takada T.
- Journal Title
  
  J Biol Chem
  
  Volume: 299 Issue: 8 Pages: 104976-104976
- DOI
  10.1016/j.jbc.2023.104976
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0152, KAKENHI-PROJECT-22K19369, KAKENHI-PROJECT-21K15293, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-23K21618
[Journal Article] Identification of a dysfunctional exon-skipping splice variant in GLUT9/SLC2A9 causal for renal hypouricemia type 2.2023
- Author(s)
  Toyoda Y, Cho SK, Tasic V, Pavelcova K, Bohata J, Suzuki H, David VA, Yoon J, Pallaiova A, Saligova J, Nousome D, Cachau R, Winkler CA, Takada T, Stiburkova B.
- Journal Title
  
  Front Genet.
  
  Volume: 13 Pages: 1048330-1048330
- DOI
  10.3389/fgene.2022.1048330
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0152, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-23K21618
[Journal Article] SNP-based heritability estimates of gout and its subtypes determined by genome-wide association studies of clinically defined gout2022
- Author(s)
  Yu Toyoda、Masahiro Nakatochi、Akiyoshi Nakayama、Yusuke Kawamura、Hirofumi Nakaoka、Kenji Wakai、Keitaro Matsuo、Hirotaka Matsuo、Kimiyoshi Ichida、Yukinori Okada、Tappei Takada、Seiko Shimizu、Yuya Shirai、Ken Yamamoto、Ituro Inoue
- Journal Title
  
  Rheumatology
  
  Volume: － Issue: 5 Pages: e144-e146
- DOI
  10.1093/rheumatology/keac597
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-23K21618, KAKENHI-PROJECT-22H04923
[Journal Article] A meta-analysis of genome-wide association studies using Japanese and Taiwanese has revealed novel loci associated with gout susceptibility2022
- Author(s)
  Chang Shun-Jen、Toyoda Yu、Kawamura Yusuke、Nakamura Takahiro、Nakatochi Masahiro、Nakayama Akiyoshi、et al.
- Journal Title
  
  Human Cell
  
  Volume: 35 Issue: 2 Pages: 767-770
- DOI
  10.1007/s13577-021-00665-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-21KK0173, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-23K21618, KAKENHI-PROJECT-22H04923
[Journal Article] OAT10/SLC22A13 Acts as a Renal Urate Re-Absorber : Clinico-Genetic and Functional Analyses With Pharmacological Impacts2022
- Author(s)
  Yu Toyoda, Yusuke Kawamura, Akiyoshi Nakayama, Keito Morimoto, Seiko Shimizu, Yuki Tanahashi, Takashi Tamura, Takaaki Kondo, Yasufumi Kato, Hirotaka Matsuo, et al.
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13 Pages: 842717-842717
- DOI
  10.3389/fphar.2022.842717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-21KK0173, KAKENHI-PROJECT-22KK0152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-23K21618, KAKENHI-PROJECT-22H04923
[Journal Article] Identification of Inhibitory Activities of Dietary Flavonoids against URAT1, a Renal Urate Re-Absorber: In Vitro Screening and Fractional Approach Focused on Rooibos Leaves.2022
- Author(s)
  Toyoda Y, Takada T, Saito H, Hirata H, Ota-Kontani A, Tsuchiya Y, Suzuki H.
- Journal Title
  
  Nutrients.
  
  Volume: 14 Issue: 3 Pages: 575-575
- DOI
  10.3390/nu14030575
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-23K21618
[Journal Article] Identification of an exporter that regulates vitamin C supply from blood to the brain2022
- Author(s)
  Miyata Hiroshi、Toyoda Yu、Takada Tappei、Hiragi Toshimitsu、Kubota Yu、Shigesawa Ryuichiro、Koyama Ryuta、Ikegaya Yuji、Suzuki Hiroshi
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 1 Pages: 103642-103642
- DOI
  10.1016/j.isci.2021.103642
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15293, KAKENHI-PROJECT-23K21618
[Journal Article] Coffee Consumption Reduces Gout Risk Independently of Serum Uric Acid Levels: Mendelian Randomization Analyses Across Ancestry Populations2022
- Author(s)
  Shirai Yuya、Nakayama Akiyoshi、Kawamura Yusuke、Toyoda Yu、Nakatochi Masahiro、Shimizu Seiko、Shinomiya Nariyoshi、Okada Yukinori、Matsuo Hirotaka、Japan Gout Genomics Consortium (Japan Gout)
- Journal Title
  
  ACR Open Rheumatology
  
  Volume: - Issue: 6 Pages: 534-539
- DOI
  10.1002/acr2.11425
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-21KK0173, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-22H04923
[Journal Article] Hepatic Niemann-Pick C1-Like 1 exacerbates non-alcoholic fatty liver disease by re-absorbing specific biliary oxysterols.2022
- Author(s)
  Yamanashi Y, Takada T, Tanaka Y, Ogata Y, Toyoda Y, Ito SM, Kitani, Oshida N, Okada K, Shoda J, Suzuki H.
- Journal Title
  
  Biomed. Pharmacother.
  
  Volume: 156 Pages: 113877-113877
- DOI
  10.1016/j.biopha.2022.113877
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07933, KAKENHI-PROJECT-22K19643, KAKENHI-PROJECT-20H04100, KAKENHI-PROJECT-20H04119, KAKENHI-PROJECT-21H03372, KAKENHI-PROJECT-20J22648, KAKENHI-PROJECT-20K08275, KAKENHI-PROJECT-21K19694
[Journal Article] Genome-wide meta-analysis between renal overload type and renal underexcretion type of clinically defined gout in Japanese populations2022
- Author(s)
  Toyoda Yu、Nakayama Akiyoshi、Nakatochi Masahiro、Kawamura Yusuke、Nakaoka Hirofumi、Yamamoto Ken、Shimizu Seiko、Ooyama Hiroshi、Ooyama Keiko、Shimizu Toru、Nagase Mitsuo、Hidaka Yuji、Ichida Kimiyoshi、Inoue Ituro、Shinomiya Nariyoshi、Matsuo Hirotaka
- Journal Title
  
  Molecular Genetics and Metabolism
  
  Volume: - Issue: 3 Pages: 00126-3
- DOI
  10.1016/j.ymgme.2022.01.100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-21KK0173, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18K08520, KAKENHI-PROJECT-19K19434, KAKENHI-PROJECT-23K21618, KAKENHI-PROJECT-22H04923
[Journal Article] Identification of Two Dysfunctional Variants in the ABCG2 Urate Transporter Associated with Pediatric-Onset of Familial Hyperuricemia and Early-Onset Gout.2021
- Author(s)
  Toyoda Y, Pavelcova K, Bohata J, Jesina P, Kubota Y, Suzuki H, Takada T, Stiburkova B.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22(4) Issue: 4 Pages: 1935-1935
- DOI
  10.3390/ijms22041935
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-19K16441
[Journal Article] Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A122021
- Author(s)
  Toyoda Yu、Kawamura Yusuke、Nakayama Akiyoshi、Nakaoka Hirofumi、Higashino Toshihide、Shimizu Seiko、Ooyama Hiroshi、Morimoto Keito、Uchida Naohiro、Shigesawa Ryuichiro、Takeuchi Kenji、Inoue Ituro、Ichida Kimiyoshi、Suzuki Hiroshi、Shinomiya Nariyoshi、Takada Tappei、Matsuo Hirotaka
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 11 Pages: 5224-5232
- DOI
  10.1093/rheumatology/keab327
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19K16441
[Journal Article] An X chromosome-wide meta-analysis based on Japanese cohorts revealed that non-autosomal variations are associated with serum urate2021
- Author(s)
  Nakatochi Masahiro、Toyoda Yu、Kanai Masahiro et al. 13th out of 17
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 9 Pages: 4430-4432
- DOI
  10.1093/rheumatology/keab404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-19K19434, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-21H03206, KAKENHI-PROJECT-23K21618
[Journal Article] Porphyrin accumulation in humans with common dysfunctional variants of ABCG2, a porphyrin transporter: potential association with acquired photosensitivity2021
- Author(s)
  Sakiyama Masayuki、Matsuo Hirotaka、Toyoda Yu、Yonekura Yuiko、Ishikawa Takahiro、Nakayama Akiyoshi、Higashino Toshihide、Kawamura Yusuke、Fujimoto Norihiro、Shinomiya Nariyoshi、Satoh Takahiro
- Journal Title
  
  Human Cell
  
  Volume: 34 Issue: 4 Pages: 1082-1086
- DOI
  10.1007/s13577-021-00534-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-16H06277
[Journal Article] Association Between Earwax-Determinant Genotypes and Acquired Middle Ear Cholesteatoma in a Japanese Population2021
- Author(s)
  Hara Satoshi、Kusunoki Takeshi、Nakagawa Hiroshi、Toyoda Yu、Nojiri Shuko、Kamiya Kazusaku、Furukawa Masayuki、Takata Yusuke、Okada Hiroko、Anzai Takashi、Matsumoto Fumihiko、Ikeda Katsuhisa
- Journal Title
  
  Otolaryngology Head and Neck Surgery
  
  Volume: - Issue: 1 Pages: 139-145
- DOI
  10.1177/01945998211000374
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09356, KAKENHI-PROJECT-18K16858, KAKENHI-PROJECT-18K09388, KAKENHI-PROJECT-21K09566, KAKENHI-PROJECT-21K09589, KAKENHI-PROJECT-18K16857, KAKENHI-PROJECT-20K21662, KAKENHI-PROJECT-21H03089
[Journal Article] Increase of serum uric acid levels associated with APOE ε2 haplotype: a clinico-genetic investigation and in vivo approach2021
- Author(s)
  Ogura Masatsune、Toyoda Yu、Sakiyama Masayuki、Kawamura Yusuke、Nakayama Akiyoshi、et al.
- Journal Title
  
  Human Cell
  
  Volume: 34 Issue: 6 Pages: 1727-1733
- DOI
  10.1007/s13577-021-00609-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-20H04100, KAKENHI-PROJECT-20K08439, KAKENHI-PROJECT-21K08143, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-23K21618
[Journal Article] Genetic epidemiological analysis of hypouricaemia from 4993 Japanese on non-functional variants of <i>URAT1/SLC22A12</i> gene2021
- Author(s)
  Nakayama Akiyoshi、Kawamura Yusuke、Toyoda Yu、Shimizu Seiko、Kawaguchi Makoto、Aoki Yuka、Takeuchi Kenji、Okada Rieko、Kubo Yoko、Imakiire Toshihiko、Iwasawa Satoko、Nakashima Hiroshi、Tsunoda Masashi、Ito Keiichi、Kumagai Hiroo、Takada Tappei、Ichida Kimiyoshi、Shinomiya Nariyoshi、Matsuo Hirotaka
- Journal Title
  
  Rheumatology
  
  Volume: 61 Issue: 3 Pages: 1276-1281
- DOI
  10.1093/rheumatology/keab545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-23K21618
[Journal Article] A Proposal for Practical Diagnosis of Renal Hypouricemia: Evidenced from Genetic Studies of Nonfunctional Variants of URAT1/SLC22A12 among 30,685 Japanese Individuals2021
- Author(s)
  Kawamura Yusuke、Nakayama Akiyoshi、Shimizu Seiko、Toyoda Yu、et al.
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 8 Pages: 1012-1012
- DOI
  10.3390/biomedicines9081012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-20H03943, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-23K21618
[Journal Article] Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients.2020
- Author(s)
  Nakayama A, Takada T, et al.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 79 Issue: 5 Pages: 657665-657665
- DOI
  10.1136/annrheumdis-2019-216644
- NAID
  120007042436
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-17H04128, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18K08520, KAKENHI-PROJECT-18K10049, KAKENHI-PROJECT-19K10659, KAKENHI-PROJECT-20K21705, KAKENHI-PROJECT-20K23152, KAKENHI-PLANNED-17H06415, KAKENHI-PUBLICLY-19H05344, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-19H03371, KAKENHI-PROJECT-19K22786, KAKENHI-PROJECT-19K22808, KAKENHI-PROJECT-18KK0229, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-20H00568
[Journal Article] Febuxostat inhibited axillary osmidrosis risk factor ATP‐binding cassette transporter C11 in vitro2020
- Author(s)
  Toyoda Yu、Takada Tappei、Suzuki Hiroshi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 47 Issue: 10 Pages: 1198-1199
- DOI
  10.1111/1346-8138.15512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16441
[Journal Article] Identification of a dysfunctional splicing mutation in the SLC22A12/URAT1 gene causing renal hypouricaemia type 1: a report on two families2020
- Author(s)
  Kawamura Yusuke、Toyoda Yu、Ohnishi Takuma、Hisatomi Ryutaro、Higashino Toshihide、Nakayama Akiyoshi、Shimizu Seiko、Yanagi Masato、Kamimaki Isamu、Fujimaru Rika、Suzuki Hiroshi、Shinomiya Nariyoshi、Takada Tappei、Matsuo Hirotaka
- Journal Title
  
  Rheumatology
  
  Volume: 59 Issue: 12 Pages: 3988-3990
- DOI
  10.1093/rheumatology/keaa461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-19K16441
[Journal Article] Omega-3 Polyunsaturated Fatty Acids Inhibit the Function of Human URAT1, a Renal Urate Re-Absorber2020
- Author(s)
  Saito Hiroki、Toyoda Yu、Takada Tappei、Hirata Hiroshi、Ota-Kontani Ami、Miyata Hiroshi、Kobayashi Naoyuki、Tsuchiya Youichi、Suzuki Hiroshi
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 6 Pages: 1601-1601
- DOI
  10.3390/nu12061601
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23793, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-20H00568
[Journal Article] Soy Isoflavone Genistein Inhibits an Axillary Osmidrosis Risk Factor ABCC11: In Vitro Screening and Fractional Approach for ABCC11-Inhibitory Activities in Plant Extracts and Dietary Flavonoids2020
- Author(s)
  Saito Hiroki、Toyoda Yu、Hirata Hiroshi、Ota-Kontani Ami、Tsuchiya Youichi、Takada Tappei、Suzuki Hiroshi
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 8 Pages: 2452-2452
- DOI
  10.3390/nu12082452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16441
[Journal Article] Inhibitory effect of Citrus flavonoids on the in vitro transport activity of human urate transporter 1 (URAT1/SLC22A12), a renal re-absorber of urate.2020
- Author(s)
  Toyoda Y, Takada T, Saito H, Hirata H, Ota-Kontani A, Kobayashi N, Tsuchiya Y, Suzuki H.
- Journal Title
  
  NPJ Sci Food.
  
  Volume: 4 Issue: 1 Pages: 3-3
- DOI
  10.1038/s41538-020-0063-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-19K16441
[Journal Article] Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels.2020
- Author(s)
  Higashino T, Morimoto K, Nakaoka H, Toyoda Y, Kawamura Y, Shimizu S, Nakamura T, Hosomichi K, Nakayama A, Ooyama K, Ooyama H, Shimizu T, Ueno M, Ito T, Tamura T, Naito M, Nakashima H, Kawaguchi M, Takao M, Kawai Y, Osada N, Ichida K, Yamamoto K, Suzuki H, Shinomiya N, Inoue I, Takada T, Matsuo H.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 79(1) Issue: 1 Pages: 164-166
- DOI
  10.1136/annrheumdis-2019-216044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0247, KAKENHI-PUBLICLY-19H05344, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-17H04128, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-16H06279, KAKENHI-PLANNED-18H05511
[Journal Article] Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice.2020
- Author(s)
  Toyoda Y, Takada T, Miyata H, Matsuo H, Kassai H, Nakao K, Nakatochi M, Kawamura Y, Shimizu S, Shinomiya N, Ichida K, Hosoyamada M, Aiba A, Suzuki H
- Journal Title
  
  Proc. Natl.Acad. Sci. USA
  
  Volume: 117 Issue: 31 Pages: 18175-18177
- DOI
  10.1073/pnas.2006958117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06478, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-19K23793, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-20H00568
[Journal Article] Familial early-onset hyperuricemia and gout associated with a newly identified dysfunctional variant in urate transporter ABCG2.2019
- Author(s)
  Toyoda Y, Pavelcova K, Klein M, Suzuki H, Takada T, Stiburkova B.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 21(1) Issue: 1 Pages: 219-219
- DOI
  10.1186/s13075-019-2007-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-19K16441
[Journal Article] Inhibitors of Human ABCG2: From Technical Background to Recent Updates With Clinical Implications.2019
- Author(s)
  Toyoda Y, Takada T, Suzuki H.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 10 Pages: 208-208
- DOI
  10.3389/fphar.2019.00208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-15H05610
[Journal Article] Identification of hepatic NPC1L1 as an NAFLD risk factor evidenced by ezetimibe-mediated steatosis prevention and recovery2019
- Author(s)
  Toyoda Yu, Takada Tappei, Umezawa Masakazu, Tomura Fumiya, Yamanashi Yoshihide, Takeda Ken, Suzuki Hiroshi
- Journal Title
  
  FASEB BioAdvances
  
  Volume: in press Issue: 5 Pages: 283-295
- DOI
  10.1096/fba.2018-00044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-17K19895
[Journal Article] Pathophysiological importance of bile cholesterol reabsorption: hepatic NPC1L1-exacerbated steatosis and decreasing VLDL-TG secretion in mice fed a high-fat diet2019
- Author(s)
  Toyoda Yu、Takada Tappei、Yamanashi Yoshihide、Suzuki Hiroshi
- Journal Title
  
  Lipids in Health and Disease
  
  Volume: 18 Issue: 1
- DOI
  10.1186/s12944-019-1179-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22797, KAKENHI-PROJECT-16H06219, KAKENHI-PROJECT-19K16441
[Journal Article] Functional Characterization of Clinically-Relevant Rare Variants in ABCG2 Identified in a Gout and Hyperuricemia Cohort2019
- Author(s)
  Toyoda Yu, Mancikova Andrea, Krylov Vladimir, Morimoto Keito, Pavelcova Katerina, Bohata Jona, Pavelka Karel, Pavlikova Marketa, Suzuki Hiroshi, Matsuo Hirotaka, Takada Tappei, Stiburkova Blanka
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 4 Pages: 363-363
- DOI
  10.3390/cells8040363
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-16H01808
[Journal Article] Are ATP-binding cassette transporter and earwax associated with the incidence of cholesteatoma?2018
- Author(s)
  Nakagawa H, Toyoda Y, Albrecht T, Tsukamoto M, Praetorius M , Ishikawa T, Kamiya K, Kusunoki T, Ikeda K, Serkan Sertel
- Journal Title
  
  Medical Hyotheses
  
  Volume: 114 Pages: 19-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10763
[Journal Article] Are human ATP-binding cassette transporter C11 and earwax associated with the incidence of cholesteatoma?2018
- Author(s)
  Nakagawa Hiroshi、Toyoda Yu、Albrecht Tobias、Tsukamoto Megumi、Praetorius Mark、Ishikawa Toshihisa、Kamiya Kazusaku、Kusunoki Takeshi、Ikeda Katsuhisa、Sertel Serkan
- Journal Title
  
  Med. Hypotheses
  
  Volume: 114 Pages: 19-22
- DOI
  10.1016/j.mehy.2018.02.030
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-16K15725, KAKENHI-PROJECT-18K09356, KAKENHI-PROJECT-18K09387, KAKENHI-PROJECT-17H04348
[Journal Article] Identification of ABCG2 as an Exporter of Uremic Toxin Indoxyl Sulfate in Mice and as a Crucial Factor Influencing CKD Progression.2018
- Author(s)
  Takada T, Yamamoto T, Matsuo H, Tan JK, Ooyama K, Sakiyama M, Miyata H, Yamanashi Y, Toyoda Y, Higashino T, Nakayama A, Nakashima A, Shinomiya N, Ichida K, Ooyama H, Fujimori S, Suzuki H
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 11147-11147
- DOI
  10.1038/s41598-018-29208-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08437, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-16H06219
[Journal Article] 健康長寿の秘訣は糖質よりも脂肪にあり！？2018
- Author(s)
  豊田優
- Journal Title
  
  Farumashia
  
  Volume: 54 Issue: 8 Pages: 814-814
- DOI
  10.14894/faruawpsj.54.8_814
- NAID
  130007429218
- ISSN
  0014-8601, 2189-7026
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-17K19895
[Journal Article] Possible association between middle ear cholesteatoma and a single nucleotide polymorphism 538G>A in ABCC11, a human earwax type determinant.2018
- Author(s)
  Kusunoki T , Nakagawa H, Tsukamoto M, Toyoda Y, Kamiya K,Okada H, Hara S, Furukawa M,
- Journal Title
  
  Journal of Molecular and Genetic Medicine
  
  Volume: 12:3 Issue: 3 Pages: 1000362-1000362
- DOI
  10.4172/1747-0862.1000362
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09356, KAKENHI-PROJECT-15H05610
[Journal Article] Investigation of the transport of xanthine dehydrogenase inhibitors by the urate transporter ABCG22018
- Author(s)
  Nakamura Makiko、Fujita Kyoko、Toyoda Yu、Takada Tappei、Hasegawa Hiroshi、Ichida Kimiyoshi
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 33 Issue: 1 Pages: 77-81
- DOI
  10.1016/j.dmpk.2017.11.002
- NAID
  210000186733
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K05937, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-15H05610
[Journal Article] Metabolomics of an <i>in vitro</i> liver model containing primary hepatocytes assembling around an endothelial cell network: comparative study on the metabolic stability and the effect of acetaminophen treatment2017
- Author(s)
  Yu Toyoda, Kasumi Kashikura, Tomoyoshi Soga, Yoh-ichi Tagawa
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 42 Issue: 4 Pages: 445-454
- DOI
  10.2131/jts.42.445
- NAID
  130005765958
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19895
[Journal Article] Clinical and molecular evidence of ABCC11 protein expression in axillary apocrine glands of patients with axillary osmidrosis2017
- Author(s)
  Yu Toyoda, Tappei Takada, Tuneaki Gomi, Hiroshi Nakagawa, Toshihisa Ishikawa and Hiroshi Suzuki
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 18(2) Issue: 2 Pages: 417-417
- DOI
  10.3390/ijms18020417
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-15K15470
[Journal Article] Spontaneous production of glutathione-conjugated forms of 1,2-dichloropropane: comparative study on metabolic activation processes of dihaloalkanes associated with occupational cholangiocarcinoma2017
- Author(s)
  Yu Toyoda, Tappei Takada, and Hiroshi Suzuki
- Journal Title
  
  Oxid. Med. Cell. Longev.
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05610
[Journal Article] Earwax phenotype related to risk factor of middle ear cholesteatoma.2017
- Author(s)
  Kusunoki T, Nakagawa H, Tsukamoto M, Toyoda Y, Kamiya K, Okada H, Hara S, Hatakeyama H, Furukawa M, Ikeda K
- Journal Title
  
  M J Otol
  
  Volume: 3 Pages: 1-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10763
[Journal Article] Multiple common and rare variants of ABCG2 cause gout2017
- Author(s)
  Higashino Toshihide、Takada Tappei、Nakaoka Hirofumi、Toyoda Yu、Stiburkova Blanka、Miyata Hiroshi、Ikebuchi Yuki、Nakashima Hiroshi、Shimizu Seiko、Kawaguchi Makoto、Sakiyama Masayuki、Nakayama Akiyoshi、Akashi Airi、Tanahashi Yuki、Kawamura Yusuke、Nakamura Takahiro、Wakai Kenji、Hosomichi Kazuyoshi 他
- Journal Title
  
  RMD Open
  
  Volume: 3 Issue: 2 Pages: e000464-e000464
- DOI
  10.1136/rmdopen-2017-000464
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19804, KAKENHI-PROJECT-17K19864, KAKENHI-PROJECT-15H02373, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-16J01063, KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17H04128
[Journal Article] 胆管がんにかかわる発がん性候補物質の胆汁排泄を発見2016
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Journal Title
  
  化学（株式会社化学同人）
  
  Volume: 71(6) Pages: 73-73
- Data Source
  KAKENHI-PROJECT-15H05610
[Journal Article] Halogenated hydrocarbon solvent-related cholangiocarcinoma risk: biliary excretion of glutathione conjugates of 1,2-dichloropropane evidenced by untargeted metabolomics analysis2016
- Author(s)
  Yu Toyoda, Tappei Takada, and Hiroshi Suzuki
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 24586-24586
- DOI
  10.1038/srep24586
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-15K15470
[Journal Article] Halogenated hydrocarbon solvent-related cholangiocarcinoma risk: biliary excretion of glutathione conjugates of 1,2-dichloropropane evidenced by untargeted metabolomics analysis.2016
- Author(s)
  Yu Toyoda, Tappei Takada, Hiroshi Suzuki
- Journal Title
  
  Sci. Rep.
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670073
[Journal Article] Halogenated hydrocarbon solvent-related cholangiocarcinoma risk: biliary excretion of glutathione conjugates of 1,2-dichloropropane evidenced by untargeted metabolomics analysis.2016
- Author(s)
  Yu Toyoda, Tappei Takada, and Hiroshi Suzuki.
- Journal Title
  
  Sci. Rep.
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05610
[Journal Article] Novel dysfunctional variant in ABCG2 as a cause of severe tophaceous gout: biochemical, molecular genetic and functional analysis.2016
- Author(s)
  Blanka Stiburkova, Hiroshi Miyata, Jakub Zavada, Michal Tomcik, Karel Pavelka, Gabriela Storkanova, Yu Toyoda, Tappei Takada, and Hiroshi Suzuki.
- Journal Title
  
  Rheumatology
  
  Volume: 55(1) Issue: 1 Pages: 191-194
- DOI
  10.1093/rheumatology/kev350
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15470, KAKENHI-ORGANIZER-22136001, KAKENHI-PROJECT-15H05610
[Journal Article] Regulation of the Axillary Osmidrosis-Associated ABCC11 Protein Stability by N-linked Glycosylation: Effect of Glucose Condition2016
- Author(s)
  Yu Toyoda, Tappei Takada, Hiroshi Miyata, Toshihisa Ishikawa, and Hiroshi Suzuki
- Journal Title
  
  PLoS ONE
  
  Volume: 11(6) Issue: 6 Pages: e0157172-e0157172
- DOI
  10.1371/journal.pone.0157172
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-16J01063, KAKENHI-PROJECT-15K15470
[Journal Article] Diagnosis of human axillary osmidrosis by genotyping of the human ABCC11 gene: Clinical practice and basic scientific evidence.2016
- Author(s)
  Yu Toyoda, Tsuneaki Gomi, Hiroshi Nakagawa, Makoto Nagakura, and Toshihisa Ishikawa.
- Journal Title
  
  Biomed. Res. Int.
  
  Volume: 2016 Pages: 7670483-7670483
- DOI
  10.1155/2016/7670483
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15470, KAKENHI-PROJECT-15H05610
[Journal Article] Halogenated hydrocarbon solvent-related cholangiocarcinoma risk: biliary excretion of glutathione conjugates of 1,2-dichloropropane evidenced by untargeted metabolomics analysis.2016
- Author(s)
  Yu Toyoda, Tappei Takada, and Hiroshi Suzuki.
- Journal Title
  
  Sci. Rep.
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15470
[Journal Article] Identification of Febuxostat as a New Strong ABCG2 Inhibitor: Potential Applications and Risks in Clinical Situations.2016
- Author(s)
  Miyata H*, Takada T*, Toyoda Y*, Matsuo H, Ichida K, Suzuki H.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 7 Pages: 518-518
- DOI
  10.3389/fphar.2016.00518
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-16J01063, KAKENHI-PROJECT-26461244
[Patent] 体臭原因物質分泌抑制剤2020
- Inventor(s)
  豊田優, 高田龍平, 鈴木洋史, 齋藤弘貴, 平田拓, 紺谷愛美
- Industrial Property Rights Holder
  国立大学法人東京大学、ポッカサッポロフード＆ビバレッジ株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-093156
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K16441
[Patent] ABCC11阻害剤2020
- Inventor(s)
  豊田優, 高田龍平, 鈴木洋史
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19K16441
[Patent] Inhibitor for axillary osmidrosis risk factor2019
- Inventor(s)
  Yu Toyoda et al
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-19K16441
[Presentation] 臨床診断された痛風患者のみによる病型分類別のゲノムワイド関連解析と遺伝率2024
- Author(s)
  松尾洋孝, 豊田優, 中杤昌弘, 中山昌喜, 河村優輔, 清水聖子, 中岡博史, 若井建志, 松尾恵太郎
- Organizer
  第34回日本疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 臨床診断された痛風患者のみによる病型分類別のゲノムワイド関連解析と遺伝率2024
- Author(s)
  松尾洋孝, 豊田優, 中杤昌弘, 中山昌喜, 河村優輔, 清水聖子, 中岡博史, 若井建志, 松尾恵太郎
- Organizer
  第34回日本疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21KK0173
[Presentation] 膜輸送体によるビタミンC・尿酸の体内動態制御2024
- Author(s)
  豊田優, 宮田大資, 窪田優, 松尾洋孝, 高田龍平
- Organizer
  日本農芸化学会2024年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] 臨床診断された痛風患者のみによる病型分類別のゲノムワイド関連解析および遺伝率2024
- Author(s)
  中山昌喜, 豊田優, 中杤昌弘, 河村優輔, 中岡博史, 市田公美, 高田龍平, 清水聖子, 清水徹, 大山博司, 大山恵子, 長瀬満夫, 日高雄二, 高田雄三, 四ノ宮成祥, 松尾洋孝
- Organizer
  第57回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-21KK0173
[Presentation] 臨床診断された痛風患者のみによる病型分類別のゲノムワイド関連解析および遺伝率2024
- Author(s)
  中山昌喜, 豊田優, 中杤昌弘, 河村優輔, 中岡博史, 市田公美, 高田龍平, 清水聖子, 清水徹, 大山博司, 大山恵子, 長瀬満夫, 日高雄二, 高田雄三, 四ノ宮成祥, 松尾洋孝
- Organizer
  第57回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 女性の血清尿酸値上昇に及ぼすABCG2機能低下の影響の定量的解析～閉経・肥満・飲酒・加齢との比較～2024
- Author(s)
  三好優香, 中島宏, 中山昌喜, 橋本逸美, 河村優輔, 清水聖子, 豊田優, 上野美紀, 早野貴美子, 四ノ宮成祥, 角田正史, 松尾洋孝
- Organizer
  第69回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] コーヒー摂取の習慣は血清尿酸値とは相関せずに痛風リスクを減少させる：日欧の人種集団におけるメンデルランダム化解析より2024
- Author(s)
  大西まなみ, 白井雄也, 野原悠希, 中山昌喜, 河村優輔, 豊田優, 染谷真澄, 中杤昌弘, 清水聖子, 四ノ宮成祥, 岡田随象, 松尾洋孝
- Organizer
  第69回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] ビタミンC輸送体SVCT2はNa+依存性の尿酸輸送体でもある：輸送特性の解析と新規実験系への応用2024
- Author(s)
  豊田優, 宮田大資, 松尾洋孝, 高田龍平
- Organizer
  第57回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] 家族性若年性高尿酸血症性腎症（FJHN, ADTKD-UMOD）と腎性低尿酸血症が合併した一例2024
- Author(s)
  中山昌喜, 清水聖子, 豊田優, 横尾隆, 四ノ宮成祥, 松尾洋孝
- Organizer
  第57回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] コーヒー摂取の習慣は血清尿酸値とは相関せずに痛風リスクを減少させる：日欧の人種集団におけるメンデルランダム化解析より2024
- Author(s)
  大西まなみ, 白井雄也, 野原悠希, 中山昌喜, 河村優輔, 豊田優, 染谷真澄, 中杤昌弘, 清水聖子, 四ノ宮成祥, 岡田随象, 松尾洋孝
- Organizer
  第69回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-21KK0173
[Presentation] 取り込み型ビタミンC輸送体による尿酸輸送の発見2024
- Author(s)
  豊田優, 宮田大資, 松尾洋孝, 高田龍平
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] 閉経とABCG2機能低下が女性の血清尿酸値上昇に及ぼす影響の検討2024
- Author(s)
  三好優香, 中山昌喜, 河村優輔, 清水聖子, 豊田優, 上野美紀, 早野貴美子, 四ノ宮成祥, 松尾洋孝
- Organizer
  第57回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 尿酸の体内動態制御におけるOAT10の生理学的重要性と薬理学的インパクト2023
- Author(s)
  豊田優, 高田龍平, 河村優輔, 中山昌喜, 森本渓音, 清水聖子, 棚橋勇紀, 田村高志, 近藤高明, 加藤泰文, 市田公美, 鈴木洋史, 小林靖, 四ノ宮成祥, 松尾洋孝
- Organizer
  第41回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] コレステロール吸収輸送体NPC1L1の病態生理学的役割2023
- Author(s)
  山梨義英、緒方裕、豊田優、伊藤紗代、高田龍平
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04100
[Presentation] Niemann-Pick C1-Like 1による非アルコール性脂肪肝の発症・増悪に関わる酸化ステロールの胆汁排泄制御2023
- Author(s)
  山梨義英、高田龍平、田中悠介、緒方裕、豊田優、伊藤（松岡）紗代、木谷真依子、押田夏海、岡田浩介、正田純一、鈴木洋史
- Organizer
  第55回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04100
[Presentation] OAT10は生理学的に重要な尿酸再吸収輸送体である2023
- Author(s)
  豊田優, 河村優輔, 中山昌喜, 清水聖子, 川口真, 高田雄三, 市田公美, 四ノ宮成祥, 松尾洋孝, 高田龍平, （以下、非学会員共同演者）, 森本渓音, 棚橋勇紀, 田村高志, 近藤高明, 加藤泰文, 鈴木洋史, 小林靖
- Organizer
  第56回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] OAT10は生理学的に重要な尿酸再吸収輸送体である2023
- Author(s)
  豊田優, 河村優輔, 中山昌喜, 清水聖子, 川口真, 高田雄三, 市田公美, 四ノ宮成祥, 松尾洋孝, 高田龍平, （以下、非学会員共同演者）, 森本渓音, 棚橋勇紀, 田村高志, 近藤高明, 加藤泰文, 鈴木洋史, 小林靖
- Organizer
  第56回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 尿酸の体内動態制御におけるOAT10の生理学的重要性と薬理学的インパクト2023
- Author(s)
  豊田優, 高田龍平, 河村優輔, 中山昌喜, 森本渓音, 清水聖子, 棚橋勇紀, 田村高志, 近藤高明, 加藤泰文, 市田公美, 鈴木洋史, 小林靖, 四ノ宮成祥, 松尾洋孝
- Organizer
  第41回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] Physiological and pharmacological characterization of OAT10/SLC22A13, a urate re-absorber in the kidney2023
- Author(s)
  Takada, T., Toyoda Y., Kawamura Y., Nakayama A., Morimoto K., Shimizu S., Shinomiya N., Kobayashi Y., Ichida K., Matsuo H
- Organizer
  The 20th Symposium on Purine and Pyrimidine Metabolism in Man (PP23)
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0173
[Presentation] 肝臓のNPC1L1による酸化ステロールの胆汁排泄抑制と非アルコール性脂肪肝の増悪2023
- Author(s)
  山梨義英、高田龍平、田中悠介、緒方裕、豊田優、伊藤紗代、木谷真依子、押田夏海、岡田浩介、正田純一、鈴木洋史
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H04100
[Presentation] トランスポーターによる尿酸・ビタミンCの体内動態制御2023
- Author(s)
  高田龍平、豊田優、宮田大資
- Organizer
  第2回生命金属科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K19369
[Presentation] ビタミンCの排出型輸送体の発見：分子同定ならびに生理的役割の解明2023
- Author(s)
  豊田優, 宮田大資, 鈴木洋史, 高田龍平
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] コーヒーは尿酸値と独立して痛風リスクを減少させる：日欧の人種集団におけるメンデルランダム化解析より2023
- Author(s)
  中山昌喜, 白井雄也, 河村優輔, 豊田優, 中杤昌弘, 清水聖子, 四ノ宮成祥, 岡田随象, 松尾洋孝
- Organizer
  第33回日本疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 細胞膜トランスポーターによる尿酸・ビタミンCの体内動態制御2023
- Author(s)
  高田龍平、豊田優、宮田大資
- Organizer
  日本膜学会「第45年会」・「膜シンポジウム2023」合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19369
[Presentation] 尿酸輸送体遺伝子ABCG2の多型解析を通したゲノム個別化看護の可能性についての検討2023
- Author(s)
  早野貴美子, 上野美紀, 中山昌喜, 杉山諒, 鳥羽美帆, 豊田優, 花岡海虹, 水田奈々子, 清水聖子, 河村優輔, 四ノ宮成祥, 松尾洋孝, （以下、非学会員共同演者）, 内田香里, 室円, 三好優香, 橋本逸美, 中島宏, 郡司俊樹, 菊池理園, 若井建志
- Organizer
  第56回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] Hepatic NPC1L1 exacerbates NAFLD by suppressing biliary excretion of oxysterols2023
- Author(s)
  Yamanashi Y, Tanaka Y, Ogata Y, Toyoda Y, Ito S, Kitani M, Oshida N, Okada K, Shoda J, Suzuki H, Takada T
- Organizer
  2023 International Joint Meetings of the 23rd International Conference on Cytochrome P450 and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics in Shizuoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04100
[Presentation] Physiological and pharmacological characterization of OAT10/SLC22A13, a urate re-absorber in the kidney2023
- Author(s)
  Takada, T., Toyoda Y., Kawamura Y., Nakayama A., Morimoto K., Shimizu S., Shinomiya N., Kobayashi Y., Ichida K., Matsuo H
- Organizer
  The 20th Symposium on Purine and Pyrimidine Metabolism in Man (PP23)
- Invited
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] コーヒー摂取の習慣は血清尿酸値とは無関係に痛風リスクを減らす：日欧の人種集団におけるゲノムワイド関連解析の結果を活用したメンデルランダム化解析より2023
- Author(s)
  河村優輔, 中山昌喜, 豊田優, 中杤昌弘, 清水聖子, 四ノ宮成祥, 岡田随象, 松尾洋孝, （以下、非学会員共同演者）, 白井雄也
- Organizer
  第56回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 非コーディング領域に存在する、腎性低尿酸血症2型の新規病因変異の同定2023
- Author(s)
  豊田優, Blanka Stiburkova, Katerina Pavelcova, Jana Bohata, Anna Pallaiova, Jana Saligova, 松尾洋孝, 高田龍平
- Organizer
  第17回トランスポーター研究会年会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] コーヒーは尿酸値とは無関係に痛風リスクを減らす：ゲノムワイド関連解析の結果を用いたメンデルランダム化解析から2022
- Author(s)
  中山昌喜, 白井雄也, 河村優輔, 豊田優, 中杤昌弘, 清水聖子, 四ノ宮成祥, 岡田随象, 松尾洋孝
- Organizer
  第40回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 腋臭症リスク因子ABCC11の機能を阻害する食品成分の探索・解析2022
- Author(s)
  豊田優, 齋藤弘貴, 平田拓, 紺谷愛美, 土屋陽一, 高田龍平, 鈴木洋史
- Organizer
  日本農芸化学会2022年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] 腎臓における尿酸輸送体としてのOAT10の分子生理学的理解2022
- Author(s)
  豊田優, 高田龍平, 河村優輔, 中山昌喜, 森本渓音, 清水聖子, 四ノ宮成祥, 小林靖, 松尾洋孝
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] 腎臓における尿酸輸送体としてのOAT10の分子生理学的理解2022
- Author(s)
  豊田優, 高田龍平, 河村優輔, 中山昌喜, 森本渓音, 清水聖子, 四ノ宮成祥, 小林靖, 松尾洋孝
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] Mendelian randomization analyses revealed that coffee consumption reduces gout risk independently of serum uric acid levels2022
- Author(s)
  A. Nakayama, Y. Shirai, Y. Kawamura, Y. Toyoda, M. Nakatochi, S. Shimizu, N. Shinomiya, Y. Okada, H. Matsuo
- Organizer
  European Crystal Network Workshop 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0173
[Presentation] 日本人集団３万人における尿酸再吸収輸送体遺伝子URAT1/SLC22A12の機能消失型変異がもたらす影響についての臨床遺伝学的検討2022
- Author(s)
  中山昌喜, 河村優輔, 豊田優, 清水聖子, 染谷真澄, 田中里沙, 森友理乃, 今給黎敏彦, 岩澤聡子, 中島宏, 角田正史, 伊藤敬一, 有澤孝吉, 嶽崎俊郎, 田中恵太郎, 高田龍平, 市田公美, 若井建志, 四ノ宮成祥, 松尾洋孝
- Organizer
  第16回トランスポーター研究会年会/JTRA2022
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 尿中尿酸排泄率と血清尿酸値の特異的な分布パターンに基づく腎性低尿酸血症の実践的な診断モデルの提案：日本人大規模集団における臨床遺伝疫学的解析より2022
- Author(s)
  染谷真澄, 河村優輔, 中山昌喜, 清水聖子, 豊田優, 鳥羽美帆, 竹田圭吾, 菊池理園, 中嶌真由子, 川口真, 鈴木聡子, 岩澤聡子, 中島宏, 角田正史, 市田公美, 若井建志, 松尾恵太郎, 四ノ宮成祥, 松尾洋孝
- Organizer
  第68回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 食品に含まれる、腋臭症リスク決定因子ABCC11の機能阻害成分の探索・解析2022
- Author(s)
  豊田優, 齋藤弘貴, 平田拓, 紺谷愛美, 土屋陽一, 高田龍平, 鈴木洋史
- Organizer
  第76回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] Urate Research and SDF/MoD2022
- Author(s)
  H. Matsuo, Y. Kawamura, Y. Toyoda, A. Nakayama
- Organizer
  2022 International Healthcare Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] URAT1遺伝子の機能低下型変異による痛風の保護効果は、ABCG2遺伝子の機能低下型変異による痛風のリスク亢進効果を上回る2022
- Author(s)
  豊田優, 河村優輔, 中山昌喜, 東野俊英, 清水聖子, 大山博司, 市田公美, 四ノ宮成祥, 高田龍平, 松尾洋孝, （以下、非学会員共同演者）, 中岡博史, 竹内研時, 井ノ上逸郎, 鈴木洋史
- Organizer
  第55回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] ビタミンC排出型輸送体の発見2022
- Author(s)
  高田龍平、宮田大資、豊田優、鈴木洋史
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K19369
[Presentation] 食品由来フラボノイドによる尿酸再吸収輸送体URAT1の機能阻害：ルイボス茶葉中の有効成分探索および同定2022
- Author(s)
  豊田優, 高田龍平, 齋藤弘貴, 平田拓, 紺谷愛美, 土屋陽一, 鈴木洋史
- Organizer
  第35回日本動物細胞工学会2022年度大会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] 腎性低尿酸血症の原因遺伝子URAT1/SLC22A12の日本人30,685名における臨床遺伝学的解析：実際的診断に向けて2022
- Author(s)
  河村優輔, 中山昌喜, 清水聖子, 豊田優, 染谷真澄, 小田悠太, 鳥羽美帆, 川口真, 鈴木聡子, 岩澤聡子, 中島宏, 高田龍平, 角田正史, 有澤幸吉, 嶽崎俊郎, 田中恵太郎, 市田公美, 若井建志, 四ノ宮成祥, 松尾洋孝
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] Clinico-genetics analyses of gout and urate: Recent progresses from Japan2022
- Author(s)
  H. Matsuo, Y. Shirai, Y. Kawamura, Y. Toyoda, M. Nakatochi, A. Nakayama, S. Shimizu, T. Takada, K. Ichida, N. Shinomiya, Y. Okada
- Organizer
  Asia-Pacific Gout Consortium 5th Annual Meeting/12th Oriental gout symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] Mendelian randomization analyses revealed that coffee consumption reduces gout risk independently of serum uric acid levels2022
- Author(s)
  A. Nakayama, Y. Shirai, Y. Kawamura, Y. Toyoda, M. Nakatochi, S. Shimizu, N. Shinomiya, Y. Okada, H. Matsuo
- Organizer
  European Crystal Network Workshop 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 新規ビタミンC排出輸送体としてのSLC2A12の同定および生理的役割の解明2022
- Author(s)
  豊田優, 宮田大資, 平木俊光, 窪田優, 重澤龍一郎, 小山隆太, 池谷裕二, 鈴木洋史, 高田龍平
- Organizer
  第40回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] Clinico-genetics analyses of gout and urate: Recent progresses from Japan2022
- Author(s)
  H. Matsuo, Y. Shirai, Y. Kawamura, Y. Toyoda, M. Nakatochi, A. Nakayama, S. Shimizu, T. Takada, K. Ichida, N. Shinomiya, Y. Okada
- Organizer
  Asia-Pacific Gout Consortium 5th Annual Meeting/12th Oriental gout symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0173
[Presentation] OAT10は腎臓に発現する生理的に重要な尿酸輸送体である2022
- Author(s)
  豊田優, 高田龍平, 河村優輔, 中山昌喜, 森本渓音, 清水聖子, 藤原慎, 鳥羽美帆, 菊池理園, 四ノ宮成祥, 小林靖, 松尾洋孝
- Organizer
  第16回トランスポーター研究会年会/JTRA2022
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] OAT10は腎臓に発現する生理的に重要な尿酸輸送体である2022
- Author(s)
  豊田優, 高田龍平, 河村優輔, 中山昌喜, 森本渓音, 清水聖子, 藤原慎, 鳥羽美帆, 菊池理園, 四ノ宮成祥, 小林靖, 松尾洋孝
- Organizer
  第16回トランスポーター研究会年会/JTRA2022
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] Substantial gout protective effect by common and rare variants of URAT1/SLC22A12 gene2021
- Author(s)
  Y. Toyoda, Y. Kawamura, A. Nakayama, H. Nakaoka, T. Higashino, S. Shimizu, H. Ooyama, K. Morimoto, N. Uchida, R. Shigesawa, K. Takeuchi, I. Inoue, K. Ichida, H. Suzuki, N. Shinomiya, T. Takada, H. Matsuo
- Organizer
  23th APLAR (Asia-Pacific League of Associations for Rheumatology) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] 尿酸輸送体による尿酸動態制御と生体防御2021
- Author(s)
  豊田優, 高田龍平, 松尾洋孝, 市田公美, 四ノ宮成祥, 鈴木洋史
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] Clinico-genetic analyses of gout/hyperuricemia and hypouricemia: Recent progress from Japan2021
- Author(s)
  Matsuo H, Takada T, Nakayama A, Toyoda Y, Kawamura Y, Shimizu S, Nakatochi M, Shirai Y, H. S, Shinomiya N, Ichida K, Okada Y.
- Organizer
  11th Oriental Gout Forum and 5th Asia-Pacific Gout Consortium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] Protective effect of common and rare variants of URAT1/SLC22A12 on gout2021
- Author(s)
  Y. Toyoda, Y. Kawamura, A. Nakayama, H. Nakaoka, T. Higashino, S. Shimizu, H. Ooyama, K. Morimoto, N. Uchida, R. Shigesawa, K. Takeuchi, I. Inoue, K. Ichida, H. Suzuki, N. Shinomiya, T. Takada, H. Matsuo
- Organizer
  The 19th Symposium on Purine and Pyrimidine Metabolism in Man / PP21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] GLUT12は血清尿酸値制御に関わる生理的に重要な新規尿酸輸送体である：in vitro機能解析とin vivo解析2021
- Author(s)
  豊田優, 高田龍平, 宮田大資, 松尾洋孝, 葛西秀俊, 中尾和貴, 中杤昌弘, 河村優輔, 清水聖子, 四ノ宮成祥, 市田公美, 細山田真, 饗場篤, 鈴木洋史
- Organizer
  第39回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] Recent findings in clinico-genetics analyses for clinically-defined gout2021
- Author(s)
  Matsuo H, Nakatochi M, Nakayama A, Kawamura Y, Toyoda Y, Shimizu S, Takada T, Ichida K, Shinomiya N, Okada Y
- Organizer
  European Crystal Network
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] ω-3脂肪酸が尿酸再吸収輸送体URAT1の尿酸輸送活性に与える影響2021
- Author(s)
  豊田優, 齋藤弘貴, 高田龍平, 平田拓, 紺谷愛美, 宮田大資, 小林直之, 土屋陽一, 鈴木洋史
- Organizer
  第75回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-23K21618
[Presentation] 肝臓のNPC1L1依存的な高脂肪食性脂肪肝とVLDL分泌の低下2020
- Author(s)
  豊田優, 高田龍平, 山梨義英, 鈴木洋史
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H04100
[Presentation] 尿酸降下薬フェブキソスタットによる腋臭症リスク因子ABCC11の阻害2020
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Organizer
  第5回トランスポーター研究会関東部会
- Data Source
  KAKENHI-PROJECT-19K16441
[Presentation] Subtype Genome-Wide Meta-Analyses of Clinically-Defined Gout Revealed Multiple Subtype-Specific Gout Loci and Enrichment of Selection Pressure on ABCG2 and ALDH22020
- Author(s)
  Kawamura Y, Nakayama A, Nakatochi M, Yamamoto K, Nakaoka H, Shimizu S, Maehara K, Kirihara M, Koyama T, Hishida A, Shimizu T, Ooyama H, Nagase M, Shirai Y, Toyoda Y, Takada T, Kamatani Y, Ichida K, Wakai K, Inoue I, Okada Y, Shinomiya N, Matsuo H.
- Organizer
  22nd Asia Pacific League of Associations for Rheumatology (APLAR 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] URAT2/OAT10の機能低下型変異は血清尿酸値と痛風リスクの低下に寄与する2020
- Author(s)
  桐原真奈, 東野俊英, 森本渓音, 中岡博史, 豊田優, 河村優輔, 清水聖子, 藤原慎, 堀江美音, 中山昌喜, 大山博司, 清水徹, 田村高志, 鈴木洋史, 井ノ上逸朗, 四ノ宮成祥, 高田龍平, 松尾洋孝
- Organizer
  第66回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] URAT2/OAT10の機能低下型ミスセンス変異は血清尿酸値と痛風リスクを共に低下させる2020
- Author(s)
  桐原真奈, 東野俊英, 森本渓音, 中岡博史, 豊田優, 河村優輔, 清水聖子, 田中里沙, 森友理乃, 中山昌喜, 大山博司, 清水徹, 田村高志, 鈴木洋史, 井ノ上逸朗, 四ノ宮成祥, 高田龍平, 松尾洋孝
- Organizer
  第38回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 尿酸トランスポーターURAT2/OAT10の機能低下は血清尿酸値および痛風リスクを低下させる2020
- Author(s)
  田中里沙, 東野俊英, 森本渓音, 中岡博史, 豊田優, 河村優輔, 清水聖子, 桐原真奈, 前原一輝, 中山昌喜, 大山博司, 清水徹, 田村高志, 鈴木洋史, 井ノ上逸朗, 四ノ宮成祥, 高田龍平, 松尾洋孝
- Organizer
  第5回トランスポーター研究会関東部会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 脂肪肝増悪因子としてのコレステロールトランスポーターNPC1L1に関する研究2020
- Author(s)
  高田龍平, 豊田優, 山梨義英, 鈴木洋史
- Organizer
  生理研研究会『上皮膜輸送の多様性・調和機構を基盤とする異分野融合研究の創出』
- Invited
- Data Source
  KAKENHI-PROJECT-20H04100
[Presentation] Ezetimibe-mediated prevention and recovery of hepatic NPC1L1-dependent dietary steatosis in mice2020
- Author(s)
  Tappei Takada, Yu Toyoda, Yoshihide Yamanashi, Hiroshi Suzuki
- Organizer
  7th FIP Pharmaceutical Sciences World Congress (PSWC2020 Virtual)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04100
[Presentation] ゲノム解析により見出された尿酸トランスポーターと尿酸降下薬に関する研究2020
- Author(s)
  高田龍平、豊田優、他
- Organizer
  第30回日本医療薬学会年会（web）
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0247
[Presentation] Functional Cooperation of Physiological Urate Transporters and Their Modification by Food Components2020
- Author(s)
  Tappei Takada, Yu Toyoda, Hirotaka Matsuo, Kimiyoshi Ichida, et al.
- Organizer
  JAACT2020 Fuchu（web）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0247
[Presentation] 消化吸収とトランスポーター　脂溶性ビタミンの消化吸収とトランスポーター2020
- Author(s)
  高田龍平, 山梨義英, 伊藤紗代[松岡], 豊田優, 山本武人, 鈴木洋史
- Organizer
  第51回日本消化吸収学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04100
[Presentation] ABCG2, a physiologically and pharmacologically important exporter in humans2020
- Author(s)
  Tappei Takada, Yu Toyoda, Hirotaka Matsuo, Kimiyoshi Ichida, et al.
- Organizer
  8th FEBS Special Meeting: ABC Proteins - from Genetic Disease to Multidrug Resistance
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0247
[Presentation] 新規NAFLD動物モデル：ヒトNPC1L1肝発現マウスを用いた脂肪肝増悪機序に関する研究2020
- Author(s)
  豊田優、高田龍平、梅澤雅和、山梨義英、武田健、鈴木洋史
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20H04100
[Presentation] ABCG2 is a physiological exporter of indoxyl sulfate, and its dysfunction accelerates the progression of chronic kidney disease2020
- Author(s)
  Takehito Yamamoto, Tappei Takada, Jeng Kae Tan, Hiroshi Miyata, Yoshihide Yamanashi, Yu Toyoda, Hiroshi Suzuki
- Organizer
  7th FIP Pharmaceutical Sciences World Congress (PSWC2020 Virtual)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04100
[Presentation] 高脂肪食を摂取した、ヒトNPC1L1肝特異的発現マウスの解析に関する研究2019
- Author(s)
  豊田優, 高田龍平, 戸村文弥, 山梨義英, 鈴木洋史
- Organizer
  第73回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-17K19895
[Presentation] Hepatic NPC1L1, a cholesterol re-absorber from bile to the liver, is a novel NAFLD risk factor: analyses of genetically-engineered model mice and pharmacological approach.2019
- Author(s)
  Takada Tappei, Toyoda Yu, Umezawa Masakazu, Tomura Fumiya, Yamanashi Yoshihide, Takeda Ken, Suzuki Hiroshi
- Organizer
  60th International Conference on the Bioscience of Lipids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19895
[Presentation] 肝臓のNPC1L1は脂肪肝増悪因子である：新規NAFLDモデルとしてのヒトNPC1L1肝発現マウスの有用性2019
- Author(s)
  豊田優, 高田龍平, 梅澤雅和, 戸村文弥, 山梨義英, 武田健, 鈴木洋史
- Organizer
  第46回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-17K19895
[Presentation] 尿酸排出トランスポーターABCG2に関する生理学的・薬理学的研究2019
- Author(s)
  高田龍平、豊田優、他
- Organizer
  生理研研究会『上皮膜・間質の機能連関と病態発現機構解明のためのストラテジー』
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0247
[Presentation] 腸管・腎尿細管の尿酸輸送と高尿酸血症2019
- Author(s)
  高田龍平、豊田優、他
- Organizer
  第50回日本消化吸収学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0247
[Presentation] ABCG2 transports urate and uremic toxin indoxyl sulfate and influences CKD progression2019
- Author(s)
  Tappei Takada, Yu Toyoda, Hirotaka Matsuo, Kimiyoshi Ichida, et al.
- Organizer
  Asia-Pacific Gout Consortium 3rd Annual Meeting (APGC 2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0247
[Presentation] Urate transporter ABCG2 is a physiological exporter of uremic toxin indoxyl sulfate and a crucial factor influencing CKD progression2019
- Author(s)
  Tappei Takada, Yu Toyoda, Hirotaka Matsuo, Kimiyoshi Ichida, et al.
- Organizer
  18th International Symposium on Purine and Pyrimidine Metabolism in Man
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0247
[Presentation] 工業用化学物質による職業性胆管がんリスクに関する研究2018
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Organizer
  第4回次世代を担う若手のためのレギュラトリーサイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] 職業性胆管がんリスク関連物質の胆汁排泄2018
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Organizer
  第13回トランスポーター研究会年会
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] ヒトABC輸送体ABCC11の遺伝子多型とアポクリン腺の性状との関連性に関する研究2018
- Author(s)
  豊田優, 森本渓音, 高田龍平, 鈴木洋史
- Organizer
  第3回トランスポーター研究会関東部会
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] コレステロール輸送体Niemann-Pick C1-Like 1の肝臓における病態生理学的重要性に関する研究2018
- Author(s)
  豊田優, 高田龍平, 戸村文弥, 山梨義英, 鈴木洋史
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] コレステロール輸送体Niemann-Pick C1-Like 1の肝臓における病態生理学的重要性に関する研究2018
- Author(s)
  豊田優, 高田龍平, 戸村文弥, 山梨義英, 鈴木洋史
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K19895
[Presentation] 職業性胆管がんリスク関連有機溶剤成分の発がん性に関する研究2018
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] Halogenated hydrocarbon solvent-related cholangiocarcinoma risk: ABCC2-mediated biliary excretion of glutathione conjugates of 1,2-dichloropropane evidenced by untargeted metabolomics analysis2017
- Author(s)
  Yu Toyoda, Tappei Takada, and Hiroshi Suzuki
- Organizer
  Gordon Research Conference 2017 “Multi-Drug Efflux Systems” Integrated Approaches to Understanding the Role of Multi-Drug Efflux Systems in Health and Disease
- Place of Presentation
  Galveston, TX, USA
- Year and Date
  2017-03-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] 職業性胆管がんリスク関連有機溶剤成分の活性化に関する研究2017
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] 生体異物およびその関連代謝物の体内動態解析：職業性胆管がん事例への応用2017
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Organizer
  サーモフィッシャーサイエンティフィック質量分析フォーラム2017
- Invited
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] 腋臭症リスク決定因子：ABCC11のヒト腋窩アポクリン腺における発現2017
- Author(s)
  豊田優, 高田龍平, 五味常明, 宮田大資, 中川大, 石川智久, 鈴木洋史
- Organizer
  第12回トランスポーター研究会年会
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] Febuxostat is a newly identified strong ABCG2 inhibitor2017
- Author(s)
  Yu Toyoda, Tappei Takada, Hiroshi Miyata, Hirotaka Matsuo, Kimiyoshi Ichida, and Hiroshi Suzuki
- Organizer
  Gordon Research Seminar 2017 “Multi-Drug Efflux Systems” Linking Molecular Mechanisms to Biological Functions of Transporters Through Innovation and Multidisciplinary Approaches
- Place of Presentation
  Galveston, TX, USA
- Year and Date
  2017-03-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] ABCC2-mediated biliary excretion of glutathione conjugates of 1,2-dichloropropane evidenced by untargeted metabolomics2017
- Author(s)
  Yu Toyoda, Tappei Takada, and Hiroshi Suzuki
- Organizer
  Gordon Research Conference 2017 "Multi-Drug Efflux Systems" Integrated Approaches to Understanding the Role of Multi-Drug Efflux Systems in Health and Disease
- Place of Presentation
  Galveston, TX, USA
- Year and Date
  2017-03-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] ヒトの腋窩アポクリン腺における腋臭症リスク決定因子ABCC11の発現に関する研究2017
- Author(s)
  豊田優, 高田龍平, 五味常明, 宮田大資, 石川智久, 鈴木洋史
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] 有機溶剤成分1,2-ジクロロプロパンに起因する胆管がんリスクと胆汁排泄機構2016
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  ウインクあいち（名古屋、愛知）
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] メタボロミクスを活用した、有機溶剤成分に起因する胆管がんリスクに関する研究2016
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Organizer
  医療薬学フォーラム2016／第24回クリニカルファーマシーシンポジウム
- Place of Presentation
  滋賀県立芸術劇場びわ湖ホール（大津、滋賀）
- Year and Date
  2016-06-25
- Invited
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] N-結合型糖鎖によるヒトABCC11タンパク質の安定性制御とグルコースによる影響2016
- Author(s)
  豊田優, 高田龍平, 宮田大資, 石川智久, 鈴木洋史
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター／東北大学（仙台、宮城）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] ビタミンKの吸収阻害を介したエゼチミブとワルファリンの薬物相互作用機序の解明2016
- Author(s)
  高田龍平、山梨義英、小西健太郎、山本武人、豊田優、増尾友佑、山本英明、田中悠介、小峰瞳子、倉内亮弥、鈴木洋史
- Organizer
  日本病院薬剤師会東北ブロック第6回学術大会
- Place of Presentation
  ホテルハマツ（福島県郡山市）
- Year and Date
  2016-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-16K15155
[Presentation] エゼチミブはビタミンKの吸収阻害を介してワルファリンの作用を増強する2016
- Author(s)
  高田龍平、山梨義英、小西健太郎、山本武人、豊田優、増尾友佑、山本英明、田中悠介、小峰瞳子、倉内亮弥、鈴木洋史
- Organizer
  第48回日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-16K15155
[Presentation] メタボロミクスを活用した、トランスポーター関連疾患の研究2016
- Author(s)
  豊田優
- Organizer
  生化学若い研究者の会 2016春のセミナー
- Place of Presentation
  東京大学（本郷、東京）
- Year and Date
  2016-04-29
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] N-結合型糖鎖によるヒトABC輸送体ABCC11タンパク質の細胞内安定性制御.2016
- Author(s)
  豊田優, 高田龍平, 宮田大資, 石川智久, 鈴木洋史.
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川、横浜）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] メタボロミクスを活用した、トランスポーター関連疾患の研究2016
- Author(s)
  豊田優
- Organizer
  生化学若い研究者の会 2016春のセミナー
- Place of Presentation
  東京
- Year and Date
  2016-04-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K15470
[Presentation] 塩素系有機洗浄剤成分による胆管がんリスク：ジクロロプロパン代謝物の胆汁排泄と関連分子機構2016
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Organizer
  第11回トランスポーター研究会年会
- Place of Presentation
  京都大学（宇治、京都）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] メタボローム解析を活用した職業性胆管がんリスクに関する研究2016
- Author(s)
  豊田優, 高田龍平, 鈴木洋史
- Organizer
  第10回メタボロームシンポジウム
- Place of Presentation
  慶應義塾大学先端生命科学研究所（鶴岡、山形）
- Year and Date
  2016-10-19
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] N-結合型糖鎖によるヒトABCC11タンパク質の安定性制御とグルコースによる影響2016
- Author(s)
  豊田優, 高田龍平, 宮田大資, 石川智久, 鈴木洋史
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K15470
[Presentation] 有機溶剤成分に起因する胆管がんリスクに関するヒト肝細胞キメラマウスを用いた検討2015
- Author(s)
  豊田優、高田龍平、鈴木洋史
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド、他（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26670073
[Presentation] 有機溶剤成分に起因する胆管癌リスク：胆管側膜輸送体を介したジクロロプロパン代謝物の胆汁排泄2015
- Author(s)
  豊田優、高田龍平、鈴木洋史
- Organizer
  第10回トランスポーター研究会年会
- Place of Presentation
  慶應義塾大学芝共立キャンパス（東京都港区）
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26670073
[Presentation] N-結合型糖鎖修飾に着眼したヒトABC輸送体ABCC11タンパク質の細胞内安定性制御機構の解析.2015
- Author(s)
  豊田優, 石川智久, 中川大.
- Organizer
  第28回日本動物細胞工学会2015年度大会
- Place of Presentation
  東北大学（宮城、仙台）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] Untargeted metabolomics analysis in ABCC11 Tg mouse.2015
- Author(s)
  Yu Toyoda, Tappei Takada, Hiroshi Nakagawa, Hiroshi Miyata, Tuneaki Gomi, Yoh-ichi Tagawa, Toshihisa Ishikawa, and Hiroshi Suzuki.
- Organizer
  Gordon Research Conference 2015 “Multi-Drug Efflux Systems” A paradigm shift from fundamental mechanisms to practical applications
- Place of Presentation
  Lucca (Barga), Italy
- Year and Date
  2015-04-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] 有機溶剤成分に起因する胆管癌リスク：胆管側膜輸送体を介したジクロロプロパン代謝物の胆汁排泄.2015
- Author(s)
  豊田優, 高田龍平, 鈴木洋史.
- Organizer
  第10回トランスポーター研究会年会
- Place of Presentation
  慶應義塾大学（東京、港区）
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] Biliary excretion of glutathione-conjugates of 1,2-dichloropropane: potential influence on the cholangiocarcinoma risk induced by the exposure to halogenated hydrocarbon solvent.2015
- Author(s)
  Yu Toyoda, Tappei Takada, Hiroshi Suzuki
- Organizer
  Gordon-Kenan Research Seminar 2015 “Multi-Drug Efflux Systems”
- Place of Presentation
  Lucca (Italy)
- Year and Date
  2015-04-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670073
[Presentation] Biomolecular characterization of human ABCC11 and its clinical implications.2015
- Author(s)
  Yu Toyoda and Toshihisa Ishikawa.
- Organizer
  Gordon-Kenan Research Seminar 2015 “Multi-Drug Efflux Systems” Learning from the Past to Innovate the Future
- Place of Presentation
  Lucca (Barga), Italy
- Year and Date
  2015-04-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] Biliary excretion of glutathione-conjugates of 1, 2-dichloropropane: potential influence on the cholangiocarcinoma risk induced by the exposure to halogenated hydrocarbon solvent.2015
- Author(s)
  Yu Toyoda, Tappei Takada, and Hiroshi Suzuki.
- Organizer
  Gordon-Kenan Research Seminar 2015 “Multi-Drug Efflux Systems” Learning from the Past to Innovate the Future
- Place of Presentation
  Lucca (Barga), Italy
- Year and Date
  2015-04-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] Halogenated hydrocarbon solvent-related cholangiocarcinoma risk: biliary excretion of glutathione conjugates of 1,2-dichloropropane.2015
- Author(s)
  豊田優, 高田龍平, 鈴木洋史.
- Organizer
  第9回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  千葉大学（千葉、千葉）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] Predicted crucial amino acid residues for substrate recognition by human ABCB1: in vitro analysis–based calculation using novel substrates for human ABCB1 from Pterogyne nitens and Magnolia sp.2015
- Author(s)
  Hiroshi Nakagawa, Kazuhiro Satake, Megumi Tsukamoto, Yu Toyoda, Onat Kadioglu, Luis Octavio Regasinie, Vanderlan da Silva Bolzani, Gert Fricker, Toshihisa Ishikawa, and Thomas Efferth.
- Organizer
  Gordon Research Conference 2015 “Multi-Drug Efflux Systems” A paradigm shift from fundamental mechanisms to practical applications
- Place of Presentation
  Lucca (Barga), Italy
- Year and Date
  2015-04-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] アデノウイルスベクターを介した一過性導入法によるヒトABC輸送体ABCC11のin vivo安定性評価.2015
- Author(s)
  豊田優, 中川大, 高田龍平, 五味常明, 石川智久, 鈴木洋史.
- Organizer
  第28回日本動物細胞工学会2015年度大会
- Place of Presentation
  東北大学（宮城、仙台）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15K15470
[Presentation] 有機溶剤成分に起因する胆管がんリスクに関するヒト肝細胞キメラマウスを用いた検討.2015
- Author(s)
  豊田優, 高田龍平, 鈴木洋史.
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド（兵庫、神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] Predicted crucial amino acid residues for substrate recognition by human ABCB1: in vitro analysis–based calculation using novel substrates for human ABCB1 from Pterogyne nitens and Magnolia sp.2015
- Author(s)
  Hiroshi Nakagawa, Kazuhiro Satake, Megumi Tsukamoto, Yu Toyoda, Onat Kadioglu, Luis Octavio Regasinie, Vanderlan da Silva Bolzani, Gert Fricker, Toshihisa Ishikawa, and Thomas Efferth.
- Organizer
  Gordon Research Conference 2015 “Multi-Drug Efflux Systems” A paradigm shift from fundamental mechanisms to practical applications
- Place of Presentation
  Lucca (Barga), Italy
- Year and Date
  2015-04-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15470
[Presentation] Biliary excretion of glutathione-conjugates of 1, 2-dichloropropane: potential influence on the cholangiocarcinoma risk induced by the exposure to halogenated hydrocarbon solvent.2015
- Author(s)
  Yu Toyoda, Tappei Takada, and Hiroshi Suzuki.
- Organizer
  Gordon-Kenan Research Seminar 2015 “Multi-Drug Efflux Systems” Learning from the Past to Innovate the Future
- Place of Presentation
  Lucca (Barga), Italy
- Year and Date
  2015-04-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15470
[Presentation] Biomolecular characterization of human ABCC11 and its clinical implications.2015
- Author(s)
  Yu Toyoda and Toshihisa Ishikawa.
- Organizer
  Gordon-Kenan Research Seminar 2015 “Multi-Drug Efflux Systems” Learning from the Past to Innovate the Future
- Place of Presentation
  Lucca (Barga), Italy
- Year and Date
  2015-04-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15470
[Presentation] アデノウイルスベクターを介した一過性導入法によるヒトABC輸送体ABCC11のin vivo安定性評価.2015
- Author(s)
  豊田優, 中川大, 高田龍平, 五味常明, 石川智久, 鈴木洋史.
- Organizer
  第28回日本動物細胞工学会2015年度大会
- Place of Presentation
  東北大学（宮城、仙台）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15H05610
[Presentation] Halogenated hydrocarbon solvent-related cholangiocarcinoma risk: biliary excretion of glutathione conjugates of 1,2-dichloropropane.2015
- Author(s)
  豊田優、高田龍平、鈴木洋史
- Organizer
  第9回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  千葉大学亥鼻キャンパス（千葉県千葉市）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-26670073
[Presentation] Untargeted metabolomics analysis in ABCC11 Tg mouse.2015
- Author(s)
  Yu Toyoda, Tappei Takada, Hiroshi Nakagawa, Hiroshi Miyata, Tuneaki Gomi, Yoh-ichi Tagawa, Toshihisa Ishikawa, and Hiroshi Suzuki.
- Organizer
  Gordon Research Conference 2015 “Multi-Drug Efflux Systems” A paradigm shift from fundamental mechanisms to practical applications
- Place of Presentation
  Lucca (Barga), Italy
- Year and Date
  2015-04-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15470
[Presentation] Biliary excretion of glutathione-conjugates of 1,2-dichloropropane: potential influence on the cholangiocarcinoma risk
- Author(s)
  豊田優、高田龍平、鈴木洋史
- Organizer
  第８回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  熊本大学薬学部（熊本県熊本市）
- Year and Date
  2014-11-15 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-26670073
[Presentation] 有機溶剤成分に起因する胆管癌リスクの検討
- Author(s)
  豊田優、高田龍平、鈴木洋史
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学、他（兵庫県神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670073
[]
[]

1. TAKADA Tappei (90376468)

# of Collaborated Projects: 8 results

# of Collaborated Products: 83 results
2. Matsuo Hirotaka (00528292)

# of Collaborated Projects: 6 results

# of Collaborated Products: 55 results
3. 中川大 (40397039)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
4. Kusunoki Takeshi (30248025)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. Yamanashi Yoshihide (20582018)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
6. 徳田慶太 (50762176)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 中山昌喜 (50876000)

# of Collaborated Projects: 2 results

# of Collaborated Products: 36 results
8. 山本健 (60274528)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 宮田大資 (90844415)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. 中岡博史 (70611193)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 市田公美 (80183169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. 早野貴美子 (40759031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 四ノ宮成祥 (40505260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
14. 関根舞 (40881496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中村好宏 (60415255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 田中光信 (30754072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 大橋勇紀 (60980852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ITOH Takehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. HOSOMICHI Kazuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 豊田敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 中谷明弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 加藤和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 近藤伸二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 森宙史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 薩秀夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 山本武人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 正田純一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 岡田浩介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 葛西秀俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 藤田恭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOYODA Yu 豊田 優

Research Projects

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Co-Researchers

新規排出型尿酸輸送体の探索・同定、健康体質に与える影響の分子生理学的理解と制御Principal Investigator

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新規尿酸輸送体の遺伝的背景の違いが健康体質に与える影響の分子生理学的理解と制御Principal Investigator

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Exploring of inhibitors for axillary osmidrosis risk factor and its physiological rolePrincipal Investigator

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Searching of hepatoprotective substances in health promotive beverages in terms of the pharmacokinetics and bioactivityPrincipal Investigator

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TOYODA Yu 豊田優