SHINOMIYA Nariyoshi 四ノ宮成祥

Researcher Number	40505260
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2023: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 分子生体制御学, 教授 2020: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 防衛医科大学校, 学校長 2016: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 分子生体制御学, 教授 2016: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 教授 2015 – 2016: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, その他部局等, 教授 … More 2014 – 2015: 防衛医科大学校, 医学教育部医学科専門課程, 教授 2011 – 2014: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 教授 2013: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 教授(Professor) 2012: 防衛医科大学校, 医学教育部医学科専門課程, 教授 2011: 防衛医科大学校, 医学教育部・医学科専門課程, 教授 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 50010:Tumor biology-related / Society medicine, Nursing, and related fields / Tumor therapeutics / Radiation science / Clinical oncology Except Principal Investigator Epidemiology and preventive medicine / Medium-sized Section 58:Society medicine, nursing, and related fields / A New Phase of Our Advanced Science and Technology Society / Basic Section 58030:Hygiene and public health-related: excluding laboratory approach … More / Medium-sized Section 1:Philosophy, art, and related fields / Basic Section 55060:Emergency medicine-related / Experimental pathology / Conflict Studies / Emergency medicine Less
Keywords	Principal Investigator COSMOS法 / ｃ－Met / 分子創薬 / 受容体型チロシンキナーゼ / c-Met / 早期診断・再発の早期検知 / 次世代シークエンサー / 包括的高感度転写産物プロファイリング法 / 浸潤性膵管癌 / 腎細胞癌 … More / 新規腫瘍マーカー / 次世代シークエンサー:NGS / 包括的高感度転写産物プロファイリング:HiCEP / 浸潤性膵管腺癌 / 淡明細胞型腎細胞癌 / Stimulator / キナーゼ阻害剤 / in silico創薬 / 抑制剤 / 低分子医薬 / Met ｓtimulator / 低分子阻害薬 / Met stimulator / Kinase阻害剤 / In silico創薬 / ｃ-Met / 刺激剤 / 阻害剤 / 予防医学・疫学 / 聴力 / QOL / 個別化予防 / 分子遺伝疫学 / デュアル・インヒビター / 分子標的治療 / デュアル・インヒビション / アロステリック効果 / 造影剤 / がん / MRイメージング / 樹状細胞 / Kinase活性 / Hot spot / ホモロジーモデリング / リード化合物 / Imatinib / 分子標的薬 / Met … More Except Principal Investigator デュアルユース / ELSI / 痛風遺伝子 / ゲノム / 分子疫学 / 遺伝子 / 尿酸 / CDMRV仮説 / サブタイプゲノムワイド関連解析 / ゲノム個別化看護・予防 / ゲノム個別化医療・予防 / 分子遺伝疫学的解析 / 尿酸輸送体 / 低尿酸血症 / 高尿酸血症 / 痛風 / ゲノム個別化栄養指導 / ゲノム個別化看護 / ゲノム個別化予防 / 科学技術ガバナンス / 世代間倫理 / ガバナンス形成 / テクノロジーアセスメント / パブリックエンゲージメント / 感染症対策 / マラリア / サイエンスカフェ / 対話 / 市民参加 / 技術的洗練 / 科学技術コミュニケーション / 合意形成 / 遺伝子ドライブ / 農業 / 先端生命科学 / ゲノム編集 / DURC / 閉経 / 女性 / 月経状況 / 遺伝子多型 / 血清尿酸値 / 軍民両用 / 先端科学技術 / 軍事研究 / Compromised hosts / 抗菌活性評価チップ / compromised hosts / 薬剤耐性菌敗血症 / Compromised hostｓ / MPLAプレコンディショニン / 抗菌活性測定チップ / 貪食細胞機能強化 / MPLAプレコンディショニング / LPSプレコンディショニング / compromised host / 薬剤耐性菌血症 / 肺炎球菌 / 特異的抗体 / anti-PPS antibody / anti-PspA antibody / 肺炎球菌表面タンパク / 莢膜多糖類 / 獲得免疫 / 貪食 / B細胞 / 公平性 / 倫理教育 / 利益配分 / 紛争 / 生物兵器 / 感染症 / 安全保障 / 公衆衛生 / バイオセキュリティ / 神経疾患 / 遺伝疫学 / パーキンソン病 / 生活習慣病 / トランスレーショナルリサーチ / トランスポーター / 痛風関連遺伝子 / ゲノムワイド関連解析 / テーラーメイド医療 / 個人差医療に基づく予防医学 / 遺伝統計学 / 個人差医療 / 予防医学 / 分子遺伝疫学 / NK細胞 / 細菌感染 / マウス熱傷モデル / 活性酸素 / 免疫不全 / CD11b陽性Kupffer細胞 / CD68陽性Kupffer細胞 / CD11b陽性クッパー細胞 / CD68陽性クッパー細胞 / IL-18 / 熱傷後感染 / クッパー細胞 / 好中球 / 複合免疫不全 / 熱傷 Less

An association between serum uric acid and genetic polymorphism among pre- and post-menoposal women
- Principal Investigator
  
  Nakashima Hiroshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  National Defense Medical College
Interdisciplinary Research for Ethical, Legal, and Social Issues on Gene Drive
- Principal Investigator
  
  藤木篤
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  A New Phase of Our Advanced Science and Technology Society
- Research Institution
  Shibaura Institute of Technology
  Kobe City College of Nursing
Development of diagnostic technique through a new, high-sensitivity gene-expression analysis: to promote secondary prevention against cancers which are difficult to detect earlyPrincipal Investigator
- Principal Investigator
  
  Shinomiya Nariyoshi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  National Defense Medical College
Molecular and epidemiological research on gout and hyperuricemia from Japan: heading toward novel genome-personalized prevention and medicine
- Principal Investigator
  
  Matsuo Hirotaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  National Defense Medical College
Development of new small molecules for Met stimulator and building up foundations of medical applicationPrincipal Investigator
- Principal Investigator
  
  Shinomiya Nariyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Defense Medical College
Novel therapeutic strategy against drug-resistant bacterial sepsis in compromised hosts focusing on enhancing bactericidal activity of macrophages
- Principal Investigator
  
  Kinoshita Manabu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  National Defense Medical College
Philosophising military research: from the perspective of "Dual-Use"
- Principal Investigator
  
  Yasuo Deguchi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 1:Philosophy, art, and related fields
- Research Institution
  Kyoto University
Genetic and epidemiological analysis of noise-induced hearing loss (NIHL) towards its tailor-made medicine and preventionPrincipal Investigator
- Principal Investigator
  
  Shinomiya Nariyoshi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Society medicine, Nursing, and related fields
- Research Institution
  National Defense Medical College
Research on Landscape
- Principal Investigator
  
  Saito Tomoya
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conflict Studies
- Research Institution
  National Institute of Public Health
Development of new dual inhibitors for c-Met targeting both allosteric and catalytic sitesPrincipal Investigator
- Principal Investigator
  
  Shinomiya Nariyoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  National Defense Medical College
Immunological properties and functions of phagocytic B cells
- Principal Investigator
  
  NAKASHIMA Masahiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Experimental pathology
- Research Institution
  National Defense Medical College
Investigation of pathophysiology of gout by molecular genetic epidemiological analysis and application to genome-tailored medicine
- Principal Investigator
  
  Matsuo Hirotaka
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  National Defense Medical College
Investigation of novel protective factors for Parkinson's disease through molecular genetic-epidemiological analysis of the gout gene
- Principal Investigator
  
  MATSUO Hirotaka
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  National Defense Medical College
Development and biological evaluation of small molecule inhibitors for Met using a new strategyPrincipal Investigator
- Principal Investigator
  
  SHINOMIYA Nariyoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical oncology
- Research Institution
  National Defense Medical College
Development of MR imaging technology and cell labeling contrast agents for tracking the biokinetics of dendritic cells.Principal Investigator
- Principal Investigator
  
  SHINOMIYA NARIYOSHI
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  National Defense Medical College
Mechanical analyses and treatment of immunodeficiency following burn injury
- Principal Investigator
  
  KINOSHITA Manabu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  National Defense Medical College

[Book] すぐに分かるＣＢＲＮ　事態対処Ｑ＆Ａ―いざという時に役立つ！2020
- Author(s)
  四ノ宮成祥、木下学編著
- Total Pages
  255
- Publisher
  イカロス出版
- ISBN
  9784802209571
- Data Source
  KAKENHI-PROJECT-18K18480
[Book] すぐに分かるCBRN事態対処Q&A2020
- Author(s)
  四ノ宮成祥、木下学
- Total Pages
  256
- Publisher
  イカロス出版
- ISBN
  4802209576
- Data Source
  KAKENHI-PROJECT-20K20493
[Book] すぐに分かるCBRN事態対処Q&A2020
- Author(s)
  四ノ宮成祥、木下学(編著）
- Total Pages
  255
- Publisher
  イカロス出版
- ISBN
  4802209576
- Data Source
  KAKENHI-PROJECT-18H02685
[Book] いざという時に役立つ！すぐに分かるCBRN事態対処Q&A2020
- Author(s)
  四ノ宮成祥、木下学　編著
- Total Pages
  244
- Publisher
  ハップ
- Data Source
  KAKENHI-PROJECT-18K18480
[Book] Hyperbaric Oxygenation Therapy:Molecular Mechanisms and Clinical Applications2020
- Author(s)
  Nariyoshi Shinomiya and Yasufumi Asai(Editors)
- Total Pages
  159
- Publisher
  Springer Nature Singapore Pte Ltd.
- ISBN
  981137838X
- Data Source
  KAKENHI-PROJECT-18H02685
[Book] In Hyperbaric Oxygenation Therapy, Molecular Mechanisms and Clinical Applications (N. Shinomiya & Y. Asai ed.)2019
- Author(s)
  Nariyoshi Shinomiya
- Total Pages
  152
- Publisher
  Springer
- ISBN
  9789811378355
- Data Source
  KAKENHI-PROJECT-18H02685
[Book] リスク学事典2019
- Author(s)
  日本リスク研究学会編（四ノ宮成祥分担執筆）
- Total Pages
  832
- Publisher
  丸善出版
- ISBN
  9784621303818
- Data Source
  KAKENHI-PROJECT-18K18480
[Book] 一目でわかる感染症対策 Q&A －医療従事者が知っておくべきこと－2019
- Author(s)
  四ノ宮成祥、加來浩器、川名明彦　編著
- Total Pages
  85
- Publisher
  創志企画
- Data Source
  KAKENHI-PROJECT-15KT0054
[Book] リスク学事典（日本リスク研究学会編）2019
- Author(s)
  四ノ宮成祥
- Total Pages
  832
- Publisher
  丸善出版
- ISBN
  9784621303818
- Data Source
  KAKENHI-PROJECT-18H02685
[Book] Regulation of Signal Transduction in Human Cell Research2018
- Author(s)
  Nariyoshi Shinomiya, Hiroaki Kataoka, Qian Xie
- Total Pages
  218
- Publisher
  Springer Nature Singapore Pte Ltd.
- ISBN
  9789811072956
- Data Source
  KAKENHI-PROJECT-15KT0054
[Book] Regulation of Signal Transduction in Human Cell Research.2018
- Author(s)
  Shinomiya Nariyoshi, Qian Xie, and Georeg F. Vande Woude
- Total Pages
  218
- Publisher
  Springer Nature Singapore Pte Ltd.
- ISBN
  9789811072956
- Data Source
  KAKENHI-PROJECT-18H02685
[Book] Regulation of Signal Transduction in Human Cell Research, Chapter7　Met Activation and Carcinogenesis2018
- Author(s)
  Shinomiya Nariyoshi, Qian Xie, George F.Vande Woude
- Total Pages
  26
- Publisher
  Springer Nature Singapore Pte Ltd.
- ISBN
- Data Source
  KAKENHI-PROJECT-15H04315
[Book] 尿酸と血糖誌、尿酸異常症の遺伝子発見から腎性低尿酸血症診療ガイドライン策定まで2016
- Author(s)
  中山昌喜、松尾洋孝、四ノ宮成祥
- Total Pages
  4
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-25293145
[Book] 「高気圧酸素治療のための医学・生理学」監訳：一般社団法人日本臨床高気圧酸素・潜水医学会　Chapter 23：酸素中毒（分担部分）2013
- Author(s)
  四ノ宮成祥（分担）
- Total Pages
  526
- Publisher
  へるす出版
- Data Source
  KAKENHI-PROJECT-23300365
[Book] 医薬の門2013
- Author(s)
  千葉俊周, 松尾洋孝, 市田公美, 四ノ宮成祥
- Total Pages
  62
- Publisher
  鳥居薬品株式会社
- Data Source
  KAKENHI-PROJECT-25293145
[Book] 痛風の遺伝子，基礎から臨床へ．医薬の門． 2013; 53:74-9.2013
- Author(s)
  千葉俊周, 松尾洋孝, 市田公美, 四ノ宮成祥
- Total Pages
  62
- Publisher
  鳥居薬品株式会社
- Data Source
  KAKENHI-PROJECT-23300365
[Book] 生命科学とバイオセキュリティ　デュアルユース・ジレンマとその対応2013
- Author(s)
  四ノ宮成祥、河原直人（編著）
- Total Pages
  362
- Publisher
  東信堂
- Data Source
  KAKENHI-PROJECT-23300365
[Book] 生命科学とバイオセキュリティデュアルユース・ジレンマとその対応2013
- Author(s)
  四ノ宮成祥, 河原直人
- Total Pages
  362
- Publisher
  東信堂
- Data Source
  KAKENHI-PROJECT-23300365
[Book] 「医療ガス情報担当者MGR研修テキスト　Vol.2　医療ガス／疾病と治療　2013年版（第3版）」　２酸素中毒（pp.92-99）　４高気圧酸素治療（pp.159-165）2013
- Author(s)
  四ノ宮成祥（分担執筆）
- Total Pages
  241
- Publisher
  一般社団法人　日本産業・医療ガス協会
- Data Source
  KAKENHI-PROJECT-23300365
[Book] 「臨床感染症ブックレット」(ゲスト編集:中嶋一彦、編集委員:前崎繁文、大曲貴夫)ミニレクチャ-10.バイオテロ-疑う状況と診断のポイント-2012
- Author(s)
  加来浩器、四ノ宮成祥
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23300365
[Book] 「Annual Review糖尿病・代謝・内分泌」(編集:寺内康夫、伊藤裕、石橋俊)5.腎性低尿酸血症の遺伝学2011
- Author(s)
  松尾洋孝、四ノ宮成祥
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23300365
[Book] 「痛風診療最前線」(企画・編集:谷口敦夫)1.遺伝要因2011
- Author(s)
  中山昌喜、松尾洋孝、四ノ宮成祥
- Publisher
  新興医学出版社
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Limiting open science? Three approaches to bottom-up governance of dual-use research of concern.2023
- Author(s)
  Yoshizawa, G., Shinomiya, N., Kawamoto, S., Kawahara, N., Kiga, D., Hanaki, K. I., & Minari, J.
- Journal Title
  
  Pathogens and Global Health
  
  Volume: - Issue: 4 Pages: 1-10
- DOI
  10.1080/20477724.2023.2265626
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20493
[Journal Article] Contiguous Governance of Synchronic and Diachronic Changes for the Use of Genome Editing Technologies2022
- Author(s)
  Minari Jusaku、Shinomiya Nariyoshi、Takashima Kayo、Yoshizawa Go
- Journal Title
  
  Frontiers in Political Science
  
  Volume: 4 Pages: 825496-825496
- DOI
  10.3389/fpos.2022.825496
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20493, KAKENHI-PROJECT-18K18480, KAKENHI-PROJECT-23K21505
[Journal Article] A meta-analysis of genome-wide association studies using Japanese and Taiwanese has revealed novel loci associated with gout susceptibility2022
- Author(s)
  Chang Shun-Jen、Toyoda Yu、Kawamura Yusuke、Nakamura Takahiro、Nakatochi Masahiro、Nakayama Akiyoshi、et al.
- Journal Title
  
  Human Cell
  
  Volume: 35 Issue: 2 Pages: 767-770
- DOI
  10.1007/s13577-021-00665-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-21KK0173, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-23K21618, KAKENHI-PROJECT-22H04923
[Journal Article] OAT10/SLC22A13 Acts as a Renal Urate Re-Absorber : Clinico-Genetic and Functional Analyses With Pharmacological Impacts2022
- Author(s)
  Yu Toyoda, Yusuke Kawamura, Akiyoshi Nakayama, Keito Morimoto, Seiko Shimizu, Yuki Tanahashi, Takashi Tamura, Takaaki Kondo, Yasufumi Kato, Hirotaka Matsuo, et al.
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13 Pages: 842717-842717
- DOI
  10.3389/fphar.2022.842717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-21KK0173, KAKENHI-PROJECT-22KK0152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-23K21618, KAKENHI-PROJECT-22H04923
[Journal Article] Coffee Consumption Reduces Gout Risk Independently of Serum Uric Acid Levels: Mendelian Randomization Analyses Across Ancestry Populations2022
- Author(s)
  Shirai Yuya、Nakayama Akiyoshi、Kawamura Yusuke、Toyoda Yu、Nakatochi Masahiro、Shimizu Seiko、Shinomiya Nariyoshi、Okada Yukinori、Matsuo Hirotaka、Japan Gout Genomics Consortium (Japan Gout)
- Journal Title
  
  ACR Open Rheumatology
  
  Volume: - Issue: 6 Pages: 534-539
- DOI
  10.1002/acr2.11425
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-21KK0173, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-22H04923
[Journal Article] Genome-wide meta-analysis between renal overload type and renal underexcretion type of clinically defined gout in Japanese populations2022
- Author(s)
  Toyoda Yu、Nakayama Akiyoshi、Nakatochi Masahiro、Kawamura Yusuke、Nakaoka Hirofumi、Yamamoto Ken、Shimizu Seiko、Ooyama Hiroshi、Ooyama Keiko、Shimizu Toru、Nagase Mitsuo、Hidaka Yuji、Ichida Kimiyoshi、Inoue Ituro、Shinomiya Nariyoshi、Matsuo Hirotaka
- Journal Title
  
  Molecular Genetics and Metabolism
  
  Volume: - Issue: 3 Pages: 00126-3
- DOI
  10.1016/j.ymgme.2022.01.100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-21KK0173, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18K08520, KAKENHI-PROJECT-19K19434, KAKENHI-PROJECT-23K21618, KAKENHI-PROJECT-22H04923
[Journal Article] First clinical practice guideline for renal hypouricemia: a rare disorder that aided the development of urate-lowering drugs for gout2021
- Author(s)
  Nakayama Akiyoshi、Matsuo Hirotaka、Abhishek Abhishek、Ichida Kimiyoshi、Shinomiya Nariyoshi、Guideline Development Committee of Clinical Practice Guideline for Renal Hypouricemia
- Journal Title
  
  Rheumatology
  
  Volume: epub Issue: 9 Pages: 3961-3963
- DOI
  10.1093/rheumatology/keab322
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-18H02685
[Journal Article] Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A122021
- Author(s)
  Toyoda Yu、Kawamura Yusuke、Nakayama Akiyoshi、Nakaoka Hirofumi、Higashino Toshihide、Shimizu Seiko、Ooyama Hiroshi、Morimoto Keito、Uchida Naohiro、Shigesawa Ryuichiro、Takeuchi Kenji、Inoue Ituro、Ichida Kimiyoshi、Suzuki Hiroshi、Shinomiya Nariyoshi、Takada Tappei、Matsuo Hirotaka
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 11 Pages: 5224-5232
- DOI
  10.1093/rheumatology/keab327
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19K16441
[Journal Article] An X chromosome-wide meta-analysis based on Japanese cohorts revealed that non-autosomal variations are associated with serum urate2021
- Author(s)
  Nakatochi Masahiro、Toyoda Yu、Kanai Masahiro et al. 13th out of 17
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 9 Pages: 4430-4432
- DOI
  10.1093/rheumatology/keab404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-19K19434, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-21H03206, KAKENHI-PROJECT-23K21618
[Journal Article] Porphyrin accumulation in humans with common dysfunctional variants of ABCG2, a porphyrin transporter: potential association with acquired photosensitivity2021
- Author(s)
  Sakiyama Masayuki、Matsuo Hirotaka、Toyoda Yu、Yonekura Yuiko、Ishikawa Takahiro、Nakayama Akiyoshi、Higashino Toshihide、Kawamura Yusuke、Fujimoto Norihiro、Shinomiya Nariyoshi、Satoh Takahiro
- Journal Title
  
  Human Cell
  
  Volume: 34 Issue: 4 Pages: 1082-1086
- DOI
  10.1007/s13577-021-00534-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-16H06277
[Journal Article] Increase of serum uric acid levels associated with APOE ε2 haplotype: a clinico-genetic investigation and in vivo approach2021
- Author(s)
  Ogura Masatsune、Toyoda Yu、Sakiyama Masayuki、Kawamura Yusuke、Nakayama Akiyoshi、et al.
- Journal Title
  
  Human Cell
  
  Volume: 34 Issue: 6 Pages: 1727-1733
- DOI
  10.1007/s13577-021-00609-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-20H04100, KAKENHI-PROJECT-20K08439, KAKENHI-PROJECT-21K08143, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-23K21618
[Journal Article] Both variants of A1CF and BAZ1B genes are associated with gout susceptibility: a replication study and meta-analysis in a Japanese population2021
- Author(s)
  Kawaguchi Makoto、Nakayama Akiyoshi、Aoyagi Yuka、Nakamura Takahiro、Shimizu Seiko、Kawamura Yusuke、Takao Mikiya、Tamura Takashi、Hishida Asahi、Nagayoshi Mako、Nagase Mitsuo、Ooyama Keiko、Ooyama Hiroshi、Shinomiya Nariyoshi、Matsuo Hirotaka
- Journal Title
  
  Human Cell
  
  Volume: 34 Issue: 2 Pages: 293-299
- DOI
  10.1007/s13577-021-00485-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-16H06277
[Journal Article] Genetic epidemiological analysis of hypouricaemia from 4993 Japanese on non-functional variants of <i>URAT1/SLC22A12</i> gene2021
- Author(s)
  Nakayama Akiyoshi、Kawamura Yusuke、Toyoda Yu、Shimizu Seiko、Kawaguchi Makoto、Aoki Yuka、Takeuchi Kenji、Okada Rieko、Kubo Yoko、Imakiire Toshihiko、Iwasawa Satoko、Nakashima Hiroshi、Tsunoda Masashi、Ito Keiichi、Kumagai Hiroo、Takada Tappei、Ichida Kimiyoshi、Shinomiya Nariyoshi、Matsuo Hirotaka
- Journal Title
  
  Rheumatology
  
  Volume: 61 Issue: 3 Pages: 1276-1281
- DOI
  10.1093/rheumatology/keab545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-23K21618
[Journal Article] A Proposal for Practical Diagnosis of Renal Hypouricemia: Evidenced from Genetic Studies of Nonfunctional Variants of URAT1/SLC22A12 among 30,685 Japanese Individuals2021
- Author(s)
  Kawamura Yusuke、Nakayama Akiyoshi、Shimizu Seiko、Toyoda Yu、et al.
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 8 Pages: 1012-1012
- DOI
  10.3390/biomedicines9081012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23152, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-20H03943, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-23K21618
[Journal Article] A comparison of thyroidal protection by stable iodine or perchlorate in the case of acute or prolonged radioiodine exposure2020
- Author(s)
  Eder Stefan、Hermann Cornelius、Lamkowski Andreas、Kinoshita Manabu、Yamamoto Tetsuo、Abend Michael、Shinomiya Nariyoshi、Port Matthias、Rump Alexis
- Journal Title
  
  Archives of Toxicology
  
  Volume: 94 Issue: 9 Pages: 3231-3247
- DOI
  10.1007/s00204-020-02809-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-18H02907
[Journal Article] 特別寄稿感染力の高いウイルスにどう対応するのか？新型コロナウイルスと消防－二次感染をどう防ぐか？－2020
- Author(s)
  四ノ宮成祥
- Journal Title
  
  J RESCUE
  
  Volume: 7 Pages: 022-025
- Data Source
  KAKENHI-PROJECT-20K20493
[Journal Article] Identification of a dysfunctional splicing mutation in the SLC22A12/URAT1 gene causing renal hypouricaemia type 1: a report on two families2020
- Author(s)
  Kawamura Yusuke、Toyoda Yu、Ohnishi Takuma、Hisatomi Ryutaro、Higashino Toshihide、Nakayama Akiyoshi、Shimizu Seiko、Yanagi Masato、Kamimaki Isamu、Fujimaru Rika、Suzuki Hiroshi、Shinomiya Nariyoshi、Takada Tappei、Matsuo Hirotaka
- Journal Title
  
  Rheumatology
  
  Volume: 59 Issue: 12 Pages: 3988-3990
- DOI
  10.1093/rheumatology/keaa461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H00568, KAKENHI-PROJECT-19K16441
[Journal Article] 解説　デュアルユースが懸念される研究とその教育2020
- Author(s)
  四ノ宮成祥
- Journal Title
  
  JBSA Newsletter
  
  Volume: Vol.10(1) Pages: 1-11
- Data Source
  KAKENHI-PROJECT-18K18480
[Journal Article] A potential mechanism of tumor progression during systemic infections via the hepatocyte growth factor (HGF)/c-Met signaling pathway.2020
- Author(s)
  Tsujimoto H, Horiguchi H, Matsumoto Y, Takahata R, Shinomiya N, Yamori T, Miyazaki H, Ono S, Saitoh D, Kishi Y, Ueno H.
- Journal Title
  
  J Clin. Med
  
  Volume: 9 Issue: 7 Pages: 2074-2074
- DOI
  10.3390/jcm9072074
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10524, KAKENHI-PROJECT-18H02685
[Journal Article] The influence of a noisy environment on hearing impairment and tinnitus: The hearing outcomes of 50-year-old male Japan ground self-defense force personnel.2020
- Author(s)
  Takihata S, Mizutari K, Morita I, Matsuo H, Nakayama A, Shimizu S, Ueno M, Ito T, Shinomiya N, Shiotani A.
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 47 Issue: 6 Pages: 931-937
- DOI
  10.1016/j.anl.2020.05.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09335, KAKENHI-PROJECT-18H02685
[Journal Article] Helicobacter pylori-Mediated Immunity and Signaling Transduction in Gastric Cancer2020
- Author(s)
  Ito Nozomi、Tsujimoto Hironori、Ueno Hideki、Xie Qian、Shinomiya Nariyoshi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 11 Pages: 3699-3699
- DOI
  10.3390/jcm9113699
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02685
[Journal Article] Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels.2020
- Author(s)
  Higashino T, Morimoto K, Nakaoka H, Toyoda Y, Kawamura Y, Shimizu S, Nakamura T, Hosomichi K, Nakayama A, Ooyama K, Ooyama H, Shimizu T, Ueno M, Ito T, Tamura T, Naito M, Nakashima H, Kawaguchi M, Takao M, Kawai Y, Osada N, Ichida K, Yamamoto K, Suzuki H, Shinomiya N, Inoue I, Takada T, Matsuo H.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 79(1) Issue: 1 Pages: 164-166
- DOI
  10.1136/annrheumdis-2019-216044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0247, KAKENHI-PUBLICLY-19H05344, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-17H04128, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-16H06279, KAKENHI-PLANNED-18H05511
[Journal Article] COVID‐19 and the boundaries of open science and innovation2020
- Author(s)
  Minari Jusaku、Yoshizawa Go、Shinomiya Nariyoshi
- Journal Title
  
  EMBO reports
  
  Volume: 21 Issue: 11
- DOI
  10.15252/embr.202051773
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20493, KAKENHI-PROJECT-19KK0002, KAKENHI-PROJECT-18H02685
[Journal Article] 新型コロナウイルスの脅威について2020
- Author(s)
  四ノ宮成祥
- Journal Title
  
  Safety NEWS
  
  Volume: 741 Pages: 8-11
- Data Source
  KAKENHI-PROJECT-20K20493
[Journal Article] Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice.2020
- Author(s)
  Toyoda Y, Takada T, Miyata H, Matsuo H, Kassai H, Nakao K, Nakatochi M, Kawamura Y, Shimizu S, Shinomiya N, Ichida K, Hosoyamada M, Aiba A, Suzuki H
- Journal Title
  
  Proc. Natl.Acad. Sci. USA
  
  Volume: 117 Issue: 31 Pages: 18175-18177
- DOI
  10.1073/pnas.2006958117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06478, KAKENHI-PROJECT-20H00566, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-19K23793, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-20H00568
[Journal Article] 解説デュアルユースが懸念される研究とその教育2020
- Author(s)
  四ノ宮成祥
- Journal Title
  
  JBSA Newsletter
  
  Volume: 10 Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20493
[Journal Article] 1. 近年の生物剤の動向と貿易管理 (【特集／バイオ・セキュリティの今日的課題】)2020
- Author(s)
  四ノ宮成祥
- Journal Title
  
  CISTECジャーナル
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20493
[Journal Article] 近年の生物剤の動向と貿易管理2020
- Author(s)
  四ノ宮成祥
- Journal Title
  
  CISTECジャーナル
  
  Volume: 187 Pages: 169-179
- Data Source
  KAKENHI-PROJECT-18K18480
[Journal Article] A Potential Role of Adhesion Molecules on Lung Metastasis Enhanced by Local Inflammation2020
- Author(s)
  HORIGUCHI HIROYUKI、TSUJIMOTO HIRONORI、SHINOMIYA NARIYOSHI、MATSUMOTO YUSUKE、SUGASAWA HIDEKAZU、YAMORI TAKAO、MIYAZAKI HIROMI、SAITOH DAIZOH、KISHI YOJI、UENO HIDEKI
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 11 Pages: 6171-6178
- DOI
  10.21873/anticanres.14637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02685
[Journal Article] A common variant of LDL receptor related protein 2 (LRP2) gene is associated with gout susceptibility: a meta-analysis in a Japanese population.2020
- Author(s)
  Akashi A, Nakayama A, Kamatani Y, Higashino T, Shimizu S, Kawamura Y, Imoto M, Naito M, Hishida A, Kawaguchi M, Takao M, Matsuo M, Takada T, Ichida K, Ooyama H, Shinomiya N, Matsuo H.
- Journal Title
  
  Hum Cell.
  
  Volume: 33 Issue: 2 Pages: 303307-303307
- DOI
  10.1007/s13577-019-00318-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-17H04128, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-20H00568
[Journal Article] Dysfunctional ABCG2 gene polymorphisms are associated with serum uric acid levels and all-cause mortality in hemodialysis patients2020
- Author(s)
  Nakashima Akio、Ichida Kimiyoshi、Ohkido Ichiro、Yokoyama Keitaro、Matsuo Hirotaka、Ohashi Yuki、Takada Tappei、Nakayama Akiyoshi、Suzuki Hiroshi、Shinomiya Nariyoshi、Urashima Mitsuyoshi、Yokoo Takashi
- Journal Title
  
  Human Cell
  
  Volume: epub ahead of print Issue: 3 Pages: 1-10
- DOI
  10.1007/s13577-020-00342-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22786, KAKENHI-PROJECT-18K16012, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-20K17259, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-18KK0247, KAKENHI-PROJECT-20H00568
[Journal Article] Development of New Biokinetic-Dosimetric Models for the Simulation of Iodine Blockade in the Case of Radioiodine Exposure in Man2019
- Author(s)
  Rump A, Eder S, Lamkowski A, Kinoshita M, Yamamoto T, Abend M, Shinomiya N, Port M
- Journal Title
  
  Drug Res (Stuttg)
  
  Volume: 69(11) Issue: 11 Pages: 583-597
- DOI
  10.1055/a-0960-5590
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-18H02907
[Journal Article] A common variant of MAF/c-MAF, transcriptional factor gene in the kidney, is associated with gout susceptibility.2018
- Author(s)
  Higashino T, Matsuo H, Okada Y, Nakashima H, Shimizu S, Sakiyama M, Tadokoro S, Nakayama A, Kawaguchi M, Komatsu M, Hishida A, Nakatochi M, Ooyama H, Imaki J, Shinomiya N.
- Journal Title
  
  Human Cell
  
  Volume: 31 Issue: 1 Pages: 10-13
- DOI
  10.1007/s13577-017-0186-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19863, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-17H04128
[Journal Article] 最近の生物災害の動向2018
- Author(s)
  四ノ宮成祥
- Journal Title
  
  CBRNE SECURITY
  
  Volume: 1 Pages: 22-27
- Data Source
  KAKENHI-PROJECT-15KT0054
[Journal Article] High-Temperature-Required Protein A2 as a Predictive Marker for Response to Chemotherapy and Prognosis in Patients with High-Grade Serous Ovarian Cancers.2017
- Author(s)
  Miyamoto, M., M. Takano, K. Iwaya, N. Shinomiya, T. Goto, M. Kato, A. Suzuki, T. Aoyama, J. Hitrata, I. Nagaoka, H. Tsuda and K. Furuya
- Journal Title
  
  Br J Cancer
  
  Volume: 116, no. 6 Issue: 6 Pages: e2-e2
- DOI
  10.1038/bjc.2016.371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-24590457
[Journal Article] バイオセキュリティのための国際的な制度とその現状2017
- Author(s)
  四ノ宮成祥、田中極子
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 35(12) Pages: 1466-1470
- Data Source
  KAKENHI-PROJECT-15KT0054
[Journal Article] Independent effects of ADH1B and ALDH2 common dysfunctional variants on gout risk.2017
- Author(s)
  Sakiyama M, Matsuo H, Akashi A, Shimizu S, Higashino T, Kawaguchi M, Nakayama A, Naito M, Kawai S, Nakashima H, Sakurai Y, Ichida K, Shimizu T, Ooyama H, Shinomiya N.
- Journal Title
  
  Scientific Report
  
  Volume: 7 Issue: 1 Pages: 2500-2500
- DOI
  10.1038/s41598-017-02528-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19863, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17H04128
[Journal Article] In vivo Lipopolysaccharide Tolerance Recruits CD11b<sup>+</sup> Macrophages to the Liver with Enhanced Bactericidal Activity and Low Tumor Necrosis Factor-Releasing Capability, Resulting in Drastic Resistance to Lethal Septicemia2017
- Author(s)
  Kinoshita Manabu、Miyazaki Hiromi、Nakashima Hiroyuki、Nakashima Masahiro、Nishikawa Makoto、Ishikiriyama Takuya、Kato Shoichiro、Iwaya Keiichi、Hiroi Sadayuki、Shinomiya Nariyoshi、Seki Shuhji
- Journal Title
  
  Journal of Innate Immunity
  
  Volume: 9 Issue: 5 Pages: 493-510
- DOI
  10.1159/000475931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08751, KAKENHI-PROJECT-15H04315
[Journal Article] Correlation between c-Met and ALDH1 contributes to the survival and tumor-sphere formation of ALDH1 positive breast cancer stem cells and predicts poor clinical outcome in breast cancer2017
- Author(s)
  Nozaki Y, Tamori S, Inada M, Katayama R, Nakane H, Minamishima O, Onodera Y, Abe M, Shiina S, Tamura K, Kodama D, Sato K, Hara Y, Abe R, Takasawa R, Yoshimori A, Shinomiya N, Tanuma S, Akimoto K.
- Journal Title
  
  Genes & Cancer
  
  Volume: 8 Issue: 7-8 Pages: 628-639
- DOI
  10.18632/genesandcancer.148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08327, KAKENHI-PROJECT-17K08933, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-15K06843
[Journal Article] Multiple common and rare variants of ABCG2 cause gout2017
- Author(s)
  Higashino Toshihide、Takada Tappei、Nakaoka Hirofumi、Toyoda Yu、Stiburkova Blanka、Miyata Hiroshi、Ikebuchi Yuki、Nakashima Hiroshi、Shimizu Seiko、Kawaguchi Makoto、Sakiyama Masayuki、Nakayama Akiyoshi、Akashi Airi、Tanahashi Yuki、Kawamura Yusuke、Nakamura Takahiro、Wakai Kenji、Hosomichi Kazuyoshi 他
- Journal Title
  
  RMD Open
  
  Volume: 3 Issue: 2 Pages: e000464-e000464
- DOI
  10.1136/rmdopen-2017-000464
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19804, KAKENHI-PROJECT-17K19864, KAKENHI-PROJECT-15H02373, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-16J01063, KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17H04128
[Journal Article] Meta-Analysis Confirms an Association between Gout and a Common Variant of Lrrc16a Locus.2017
- Author(s)
  Ogata, H., H. Matsuo, M. Sakiyama, T. Higashino, M. Kawaguchi, A. Nakayama, M. Naito, H. Ooyama, K. Ichida and N. Shinomiya.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 27, no. 3 Issue: 3 Pages: 553-555
- DOI
  10.1080/14397595.2016.1218413
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-26461244, KAKENHI-PROJECT-15K15227
[Journal Article] Met4 Expression Predicts Poor Prognosis of Gastric Cancers with Helicobacter Pylori Infection2017
- Author(s)
  Sakamoto, N., H. Tsujimoto, R. Takahata, B. Cao, P. Zhao, N. Ito, H. Shimazaki, T. Ichikura, K. Hase, G. F. Vande Woude and N. Shinomiya.
- Journal Title
  
  Cancer Sci
  
  Volume: 108, no. 3 Issue: 3 Pages: 322-330
- DOI
  10.1111/cas.13146
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315
[Journal Article] 新たに持ち上がるバイオセキュリティ問題2017
- Author(s)
  四ノ宮成祥
- Journal Title
  
  CBRNE2 protection Magazine
  
  Volume: 9 Pages: 8-12
- Data Source
  KAKENHI-PROJECT-15KT0054
[Journal Article] GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.2017
- Author(s)
  Nakayama A, Nakaoka H, Yamamoto K, Sakiyama M, Shaukat A, Toyoda Y, Okada Y, Ohkawa Y,他39名
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 76 Issue: 5 Pages: 869-877
- DOI
  10.1136/annrheumdis-2016-209632
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-15H05610, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-25440254, KAKENHI-PROJECT-26461244, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17K19356, KAKENHI-PROJECT-15H02373, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-17H04128
[Journal Article] Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus.2016
- Author(s)
  M. Sakiyama, H. Matsuo, H. Nakaoka, K. Yamamoto, A. Nakayama, T. Nakamura, S. Kawai, R. Okada, H. Ooyama, T. Shimizu, and N. Shinomiya
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 25360-25360
- DOI
  10.1038/srep25360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-15H02373, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-15K15227
[Journal Article] あなたのまちの危険物質を考える（3）～CBRNから身を守るための基礎知識とリスクコミュニケーション～　身近に存在する生物兵器リスク2016
- Author(s)
  四ノ宮　成祥
- Journal Title
  
  リスク対策.com
  
  Volume: 54 Pages: 72-72
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15KT0054
[Journal Article] 生命科学のデュアルユース論議と機能獲得研究の現状2016
- Author(s)
  四ノ宮成祥
- Journal Title
  
  軍縮研究:Disarmament Review
  
  Volume: 7 Pages: 28-38
- Open Access
- Data Source
  KAKENHI-PROJECT-15KT0054
[Journal Article] Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2.2016
- Author(s)
  Matsuo H, et al.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 31003-31003
- DOI
  10.1038/srep31003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-26461244, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-16H06277
[Journal Article] The Effects of URAT1/SLC22A12 Nonfunctional Variants, R90H and W258X, on Serum Uric Acid Levels and Gout/hyperuricemia Progression2016
- Author(s)
  Sakiyama M, Matsuo H, Shimizu S et al.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 20148-20148
- DOI
  10.1038/srep20148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461244, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-16K10181
[Journal Article] Expression of a Human Npt1/Slc17a1 Missense Variant Which Increases Urate Export2016
- Author(s)
  Sakiyama, M., H. Matsuo, S. Nagamori, W. Ling, Y. Kawamura, A. Nakayama, T. Higashino, T. Chiba, K. Ichida, Y. Kanai and N. Shinomiya
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 35, no. 10-12 Issue: 10-12 Pages: 536-542
- DOI
  10.1080/15257770.2016.1149192
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-26461244
[Journal Article] Fluorescence Multispectral Imaging-Based Diagnostic System for Atherosclerosis.2016
- Author(s)
  Ho, C. S., T. Horiuchi, H. Taniguchi, A. Umetsu, K. Hagisawa, K. Iwaya, K. Nakai, A. Azmi, N. Zulaziz, A. Azhim, N. Shinomiya and Y. Morimoto
- Journal Title
  
  Biomed Eng Online
  
  Volume: 15, no. 1 Issue: 1 Pages: 98-98
- DOI
  10.1186/s12938-016-0220-z
- NAID
  130005163581
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-24590457, KAKENHI-PROJECT-16K12885
[Journal Article] Abdominal Infection Suppresses the Number and Activity of Intrahepatic Natural Killer Cells and Promotes Tumor Growth in a Murine Liver Metastasis Model2016
- Author(s)
  Matsumoto, Y., Tsujimoto, H., Ono, S., Shinomiya, N., Miyazaki, H., Hiraki, S., Takahata, R., Yoshida, K., Saitoh, D., Yamori, T., Yamamoto, J., and Hase, K.
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 23, Supplement 2 Issue: S2 Pages: 257-265
- DOI
  10.1245/s10434-015-4466-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-16H05105
[Journal Article] NRF2 Is a Key Target for Prevention of Noise-Induced Hearing Loss by Reducing Oxidative Damage of Cochlea2016
- Author(s)
  Honkura, Y. Matsuo, H. Murakami, S. Sakiyama, M. Mizutari, K. Shiotani, A. Yamamoto, M. Morita, I. Shinomiya, N. Kawase, T. Katori, Y. Motohashi, H.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 19329-19329
- DOI
  10.1038/srep19329
- NAID
  130005260938
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462572, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-15K18999, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25293145, KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-15H04315
[Journal Article] Common variant of PDZ domain containing 1 (PDZK1) gene is associated with gout susceptibility: A replication study and meta-analysis in Japanese population.2016
- Author(s)
  Higashino T, et al.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 31 Issue: 6 Pages: 464-466
- DOI
  10.1016/j.dmpk.2016.07.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-15K15227
[Journal Article] Up-Regulation of Antioxidant Proteins in the Plasma Proteome During Saturation Diving: Unique Coincidence under Hypobaric Hypoxia2016
- Author(s)
  Domoto, H., K. Iwaya, F. Ikomi, H. Matsuo, Y. Tadano, S. Fujii, K. Tachi, Y. Itoh, M. Sato, K. Inoue and N. Shinomiya
- Journal Title
  
  PLoS One
  
  Volume: 11, no. 10 Issue: 10 Pages: e0163804-e0163804
- DOI
  10.1371/journal.pone.0163804
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-24590457
[Journal Article] ABCG2 variant has opposing effects on onset ages of Parkinson's disease and gout.2015
- Author(s)
  Matsuo H, Tomiyama H, Satake W, Chiba T, Onoue H, Kawamura Y, Nakayama A, ShimizuS, Sakiyama M, Funayama M, Nishioka K, Shimizu T, Kaida K, Kamakura K, Toda T, Hattori N, ShinomiyaN.
- Journal Title
  
  Ann Clin Transl Neurol
  
  Volume: 2 Issue: 3 Pages: 302-306
- DOI
  10.1002/acn3.167
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22129006, KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-24390224, KAKENHI-PUBLICLY-25110720, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25461291, KAKENHI-PROJECT-25461292, KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-25670420, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25713015
[Journal Article] Photodynamic therapy mediates innate immune responses via fibroblast-macrophage interactions.2015
- Author(s)
  4.Zulaziz N, Azhim A, Himeno N, Tanaka M, Satoh Y, Kinoshita M, Miyazaki H, Saitoh D, Shinomiya N, Morimoto Y.
- Journal Title
  
  Hum. Cell
  
  Volume: 28 Issue: 4 Pages: 159-166
- DOI
  10.1007/s13577-015-0118-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670569, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25293369, KAKENHI-PROJECT-26293295
[Journal Article] Common variant of ALPK1 is not associated with gout: a replication study.2015
- Author(s)
  Chiba T, Matsuo H, et al.
- Journal Title
  
  Hum Cell
  
  Volume: 28 Issue: 1 Pages: 1-4
- DOI
  10.1007/s13577-014-0103-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25293145
[Journal Article] Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.2015
- Author(s)
  Matsuo H, et al.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 印刷中 Issue: 4 Pages: 652-659
- DOI
  10.1136/annrheumdis-2014-206191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-24590457, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-25440254, KAKENHI-PROJECT-26461244
[Journal Article] NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout.2015
- Author(s)
  Chiba T, Matsuo H, Kawamura Y, Nagamori S, Nishiyama T, Wei L, Nakayama A, Nakamura T, Sakiyama M, Takada T, Taketani Y, Suma S, Naito M, Oda T, Kumagai H, Moriyama Y, Ichida K, Shimizu T, Kanai Y, Shinomiya N.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 67(1) Issue: 1 Pages: 281-287
- DOI
  10.1002/art.38884
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590702, KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PUBLICLY-25136714, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-26461244, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25253008
[Journal Article] Carrier frequency of the GJB2 mutations that cause hereditary hearing loss in the Japanese population.2015
- Author(s)
  Taniguchi M, Matsuo H, et al.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 60 Issue: 10 Pages: 613-617
- DOI
  10.1038/jhg.2015.82
- NAID
  120005697967
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-23229009, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-26293369
[Journal Article] Ebolaウイルス病アウトブレイクに見る“即応能”の重要性2015
- Author(s)
  四ノ宮　成祥
- Journal Title
  
  CBRNE2 protection magazine
  
  Volume: 005 Pages: 32-38
- Data Source
  KAKENHI-PROJECT-15KT0054
[Journal Article] High-temperature-required protein A2 as a predictive marker for response to chemotherapy and prognosis in patients with high-grade serous ovarian cancers2015
- Author(s)
  Miyamoto, M., Takano, M., Iwaya, K., Shinomiya, N., Goto, T., Kato, M., Suzuki, A., Aoyama, T., Hirata, J., Nagaoka, I., Tsuda, H., and Furuya, K.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 112 Issue: 4 Pages: 739-744
- DOI
  10.1038/bjc.2015.1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04315
[Journal Article] ABCG2 dysfunction increases the risk of renal overload hyperuricemia.2014
- Author(s)
  Matsuo H, Takada T, Nakayama A, Shimizu T, Sakiyama M, Shimizu S, Chiba T, Nakashima H, Nakamura T, Takada Y, Sakurai Y, Hosoya T, Shinomiya N, Ichida K.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293145
[Journal Article] A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility2014
- Author(s)
  Sakiyama, M.　Matsuo, H.　Shimizu, S.　Chiba, T.　Nakayama, A.　Takada, Y.　Nakamura, T.　Takada, T.　Morita, E.　Naito, M.　Wakai, K.　Inoue, H.　Tatsukawa, S.　Sato, J.　Shimono, K.　Makino, T.　Satoh, T.　Suzuki, H.　Kanai, Y.　Hamajima, N.　Sakurai, Y.　Ichida, K.　Shimizu, T.　Shinomiya, N.
- Journal Title
  
  Hum Cell
  
  Volume: 27(1) Issue: 1 Pages: 1-4
- DOI
  10.1007/s13577-013-0081-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23591205, KAKENHI-PROJECT-23790060, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25461719, KAKENHI-PROJECT-221S0001
[Journal Article] Common variants of a urate-associated gene LRP2 are not associated with gout susceptibility2014
- Author(s)
  Nakayama, A.　Matsuo, H.　Shimizu, T.　Takada, Y.　Nakamura, T.　Shimizu, S.　Chiba, T.　Sakiyama, M.　Naito, M.　Morita, E.　　Ichida, K.　Shinomiya, N.
- Journal Title
  
  Rheumatol Int
  
  Volume: 34(4) Issue: 4 Pages: 473-6
- DOI
  10.1007/s00296-013-2924-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-25293145
[Journal Article] A common variant of organic anion transporter 4 (OAT4/ SLC22A11) gene is associated with renal underexcretion type gout.2014
- Author(s)
  Sakiyama M, Matsuo H, Shimizu S, Nakashima H, Nakayama A, Chiba T, Naito M, Takada T, Suzuki H, Hamajima N, Ichida K, Shimizu T, Shinomiya N.
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: in press
- NAID
  130004463357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293145
[Journal Article] ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload2014
- Author(s)
  Matsuo, H.　Nakayama, A.　Sakiyama, M.　et al.
- Journal Title
  
  Sci Rep
  
  Volume: 4：3755 Issue: 1 Pages: 1-5
- DOI
  10.1038/srep03755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23591205, KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-221S0002
[Journal Article] Identification of a hypouricemia patient with SLC2A9 R380W, a pathogenic mutation for renal hypouricemia type 2.2014
- Author(s)
  Chiba T, Matsuo H, Nagamori S, Nakayama A, Kawamura Y, Shimizu S, Sakiyama M, Hosoyamada M, Kawai S, Okada R, Hamajima N, Kanai Y, Shinomiya N.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293145
[Journal Article] Preconditioning methods influence tumor property in an orthotopic bladder urothelial carcinoma rat model2014
- Author(s)
  Miyazaki, K.　Morimoto, Y.　Nishiyama, N.　Satoh, H.　Tanaka, M.　Shinomiya, N.　Ito, K.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 2(1) Issue: 1 Pages: 65-70
- DOI
  10.3892/mco.2013.214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Promoting Education of Dual-Use Issues for Life Scientists: A Comprehensive　Approach2013
- Author(s)
  Minehata, M.　Sture, J.　Shinomiya, N.　Whitby, S.　Dando, M.
- Journal Title
  
  Journal of Disaster Research
  
  Volume: 8(4) Pages: 674-685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Linezolid and vancomycin decrease the therapeutic effect of methylene blue-photodynamic therapy in a mouse model of MRSA bacterial arthritis2013
- Author(s)
  Tanaka, M.　Mroz, P.　Dai, T.　Huang, L.　Morimoto, Y.　Kinoshita, M.　Yoshihara, Y.　Shinomiya, N.　Seki, S.　Nemoto, K.　Hamblin, M. R.
- Journal Title
  
  Photochem Photobiol
  
  Volume: 89(3) Issue: 3 Pages: 679-82
- DOI
  10.1111/php.12040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23659599, KAKENHI-PROJECT-23659628, KAKENHI-PROJECT-25293369
[Journal Article] Common dysfunctional variants in ABCG2 are a major cause of early-onset gout.2013
- Author(s)
  Matsuo, H.　Ichida, K.　Takada, T. et al.
- Journal Title
  
  Scientific reports
  
  Volume: 3：2014 Issue: 1 Pages: 2014-2014
- DOI
  10.1038/srep02014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23591205, KAKENHI-PROJECT-23591340, KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25670307
[Journal Article] 高圧環境の物理・生理学2013
- Author(s)
  四ノ宮成祥
- Journal Title
  
  日本臨床高気圧酸素・潜水医学会雑誌
  
  Volume: 10巻1号 Pages: 8-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Linezolid and vancomycin decrease the therapeutic effect of methylene blue-photodynamic therapy in a mouse model of MRSA bacterial arthritis2013
- Author(s)
  Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hamblin MR
- Journal Title
  
  Photochem Photobiol
  
  Volume: 89(3) Pages: 679-682
- Data Source
  KAKENHI-PROJECT-23659599
[Journal Article] Bioweapons and Dual-Use Research of Concern2013
- Author(s)
  Shinomiya, N.　Minehata, M.　Dando, M.
- Journal Title
  
  Journal of Disaster Research
  
  Volume: 8(4) Pages: 654-666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy2013
- Author(s)
  Xie Q., Su Y., Dykema K., Johnson J., Koeman J., De Giorgi V., Huang A., Schlegel R., Essenburg C., Kang L., Iwaya K., Seki S., Khoo S.K., Zhang B., Buonaguro F., Marincola F. M., Furge K., Vande Woude G.F., and Shinomiya N
- Journal Title
  
  Genes Cancer
  
  Volume: 4 Issue: 7-8 Pages: 247-260
- DOI
  10.1177/1947601913501075
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] ABCG2 SNP typing by HRM method; an effective method for gout/hyperuricemia risk evaluation.2013
- Author(s)
  Takada Y, Matsuo H, Sakiyama M, Nakayama A, Fuji A, Shimizu S, Chiba T, Nakasima H, Matsumura K, Suzuki K, Hamajima N, Niwa K, Suzuki S, Uchino S, Kobayashi Y, Shinomiya N.
- Journal Title
  
  J Clin Welfare
  
  Volume: 10 Pages: 64-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670307
[Journal Article] Increased xCT expression correlates with tumor invasion and outcome in patients with glioblastomas2013
- Author(s)
  Takeuchi, S.　Wada, K.　Toyooka, T.　Shinomiya, N.　Shimazaki, H.　Nakanishi, K.　Nagatani, K.　Otani, N.　Osada, H.　Uozumi, Y.　Matsuo, H.　Nawashiro, H.
- Journal Title
  
  Neurosurgery
  
  Volume: 72(1) Issue: 1 Pages: 33-41
- DOI
  10.1227/neu.0b013e318276b2de
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Increased xCT expression correlates with tumor invasion and outcome in patients with glioblastomas2013
- Author(s)
  Takeuchi S, Wada K, Toyooka T, Shinomiya N, Shimazaki H, Nakanishi K, Nagatani K, Otani N, Osada H, Uozumi Y
- Journal Title
  
  Neurosurgery
  
  Volume: 72(1) Pages: 33-41
- Data Source
  KAKENHI-PROJECT-23659599
[Journal Article] A common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility2013
- Author(s)
  Nakayama, A.　Matsuo, H.　Shimizu, T.　Ogata, H.　Takada, Y.　Nakashima, H.　Nakamura, T.　Shimizu, S.　Chiba, T.　Sakiyama, M.　Ushiyama, C.　Takada, T.　Inoue, K.　Kawai, S.　Hishida, A.　Wakai, K.　Hamajima, N.　Ichida, K.　Sakurai, Y.　Kato, Y.　Shimizu, T.　Shinomiya, N.
- Journal Title
  
  Hum Cell
  
  Volume: 26(4) Issue: 4 Pages: 133-6
- DOI
  10.1007/s13577-013-0073-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23591205, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-221S0001
[Journal Article] L-Leucine induces growth arrest and persistent ERK activation in glioma cells2012
- Author(s)
  Takeuchi S., Nawashiro H., Wada K., Nomura N., Toyooka T., Otani N., Osada H., Matsuo H., and Shinomiya N
- Journal Title
  
  Amino Acids
  
  Volume: 43(2) Issue: 2 Pages: 717-24
- DOI
  10.1007/s00726-011-1122-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Optimal photosensitizers for photodynamic therapy of infections should kill bacteria but spare neutrophils2012
- Author(s)
  Tanaka M, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hamblin M, Dai T, Huang L, Morimoto Y
- Journal Title
  
  Photochem. Photobiol
  
  Volume: 88 Pages: 227-32
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] I. 特殊環境における感染症 3. バイオテロの可能性とその対策2012
- Author(s)
  四ノ宮成祥
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 101(11) Pages: 3103-3113
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Photodynamic therapy can induce a protective innate immune response against murine bacterial arthritis via neutrophil accumulation2012
- Author(s)
  Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Nemoto K, Shinomiya N, Seki S, Hamblin M
- Journal Title
  
  PLoS One
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Characterization of mouse liver phagocytic B cells in innate immunity.2012
- Author(s)
  Nakashima, M
- Journal Title
  
  J. Leukocyte. Biol.
  
  Volume: 91 Issue: 4 Pages: 537-546
- DOI
  10.1189/jlb.0411214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592027, KAKENHI-PROJECT-23300365
[Journal Article] Photodynamic therapy using intra-articular Photofrin for murine MRSA arthritis : biphasic light dose response for neutrophil-mediated antibacterial effect2011
- Author(s)
  Tanaka, M., Kinoshita, M., Yoshihara, Y., Shinomiya, N., Seki, S., Nemoto, K., Hamblin, M.R., Morimoto, Y.
- Journal Title
  
  Lasers Surg Med
  
  Volume: 43 Issue: 3 Pages: 221-229
- DOI
  10.1002/lsm.21037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23659628
[Journal Article] Photodynamic therapy using intra-articular photofrin for murine MRSA arthritis: biphasic light dose response for neutrophil-mediated antibacterial effect2011
- Author(s)
  Tanaka M, Kinoshita M, Yoshihara Y, Shinomiya S, Seki S, Nemoto K, Hamblin M, Morimoto Y
- Journal Title
  
  Laser Surg Med
  
  Volume: 43 Pages: 221-229
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] The immunologic outcome of enhanced function of mouse liver lymphocytes and Kupffer cells by high-fat-cholesterol diet2011
- Author(s)
  Shono S, Habu Y, Nakashima M, Sato A, Nakashima H, Miyazaki H, Kinoshita M, Tsumatori G, Shinomiya N, Seki S
- Journal Title
  
  SHOCK
  
  Volume: 36 Pages: 484-93
- NAID
  40019087222
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Pathogenic GLUT9 mutations causing renal hypouricemia type 2 (RHUC2)2011
- Author(s)
  Y.Kawamura, H.Matsuo. T.Chiba, S.Nagamori, A.Nakayama, H.Inoue, Y.Utsumi, T.Oda, J.Nishiyama, Y.Kanai, N.Shinomiya
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 30 Issue: 12 Pages: 1105-1111
- DOI
  10.1080/15257770.2011.623685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689021, KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23659339
[Journal Article] ABCG2/BCRP dysfunction as a major cause of gout2011
- Author(s)
  H.Matsuo, T.Takada, K.Ichida, T.Nakamura, A.Nakayama, H.Suzuki, T.Hosoya, N.Shinomiya
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 30 Issue: 12 Pages: 1117-1128
- DOI
  10.1080/15257770.2011.633954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689021, KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23591205, KAKENHI-PROJECT-23659339, KAKENHI-PROJECT-23689008
[Journal Article] Everolimus and giant-cell astrocytomas in tuberous sclerosis2011
- Author(s)
  Nawashiro H. and Shinomiya N
- Journal Title
  
  N Engl J Med
  
  Volume: 364 Issue: 6 Pages: 576-577
- DOI
  10.1056/nejmc1013587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] The immunologic outcome of enhanced function of mouse liver lymphocytes and Kupffer cells by high-fat and high-cholesterol diet2011
- Author(s)
  Shono, S., Habu, Y, Nakashima, M., Sato, A., Nakashima, H., Miyazaki, H., Kinoshita, M., Tsumatori, G., Shinomiya, N., Seki, S.
- Journal Title
  
  Shock
  
  Volume: 36 Issue: 5 Pages: 484-493
- DOI
  10.1097/shk.0b013e31822dc6e4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Enhancement of neutrophil function by IL-18 therapy protects burn-injured mice from MRSA infection.2011
- Author(s)
  Kinoshita M, Miyazaki H., Ono S, Inatsu, A., Nakashima, H., Tsujimoto, H., Shinomiya, N., Saitoh, D., Seki, S
- Journal Title
  
  Infect Immun
  
  Volume: 79 Pages: 2670-80
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans2011
- Author(s)
  A.Nakayama, H.Matsuo. T.Takada, K.Ichida, T.Nakamura, Y.Ikebuchi, K.Ito, T.Hosoya, Y.Kanai, H.Suzuki, N.Shinomiya
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 30 Issue: 12 Pages: 1091-1097
- DOI
  10.1080/15257770.2011.633953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689021, KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23659339, KAKENHI-PROJECT-23689008
[Journal Article] Down-regulation of glial fibrillary acidic protein and vimentin by RNA interference improves acute urinary dysfunction associated with spinal cord injury in rats2011
- Author(s)
  Toyooka, T., Nawashiro, H., Shinomiya, N., Shima, K.
- Journal Title
  
  J Neurotrauma
  
  Volume: 28 Issue: 4 Pages: 607-618
- DOI
  10.1089/neu.2010.1520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Identification of ABCG2 dysfunction as a major factor contributing to gout2011
- Author(s)
  H.Matsuo, T.Takada, K.Ichida, T.Nakamura, A.Nakayama, Y.Takada, C.Okada, Y.Sakurai, T.Hosoya, Y.Kanai, H.Suzuki, N.Shinomiya
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 30 Issue: 12 Pages: 1098-1104
- DOI
  10.1080/15257770.2011.627902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689021, KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23659339, KAKENHI-PROJECT-23689008
[Journal Article] Airport quarantine inspection, follow-up observation, and the prevention of pandemic influenza2011
- Author(s)
  Fujita, M., Sato, H., Kaku, K., Tokuno, S., Kanatani, Y., Suzuki, S., Shinomiya, N.
- Journal Title
  
  Aviat Space Environ Med
  
  Volume: 82 Issue: 8 Pages: 782-789
- DOI
  10.3357/asem.3023.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Enhancement of Neutrophil Function by Interleukin-18 Therapy Protects Burn-Injured Mice from Methicillin-Resistant Staphylococcus aureus2011
- Author(s)
  Kinoshita, M., Miyazaki, H., Ono, S., Inatsu, A., Nakashima, H., Tsujimoto, H., Shinomiya, N., Saitoh, D., Seki, S.
- Journal Title
  
  Infect Immun
  
  Volume: 79 Issue: 7 Pages: 2670-2680
- DOI
  10.1128/iai.01298-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Implementing Biosecurity Education : Approaches, Resources and Programmes2011
- Author(s)
  Minehata, M., Sture, J., Shinomiya, N., Whitby, S.
- Journal Title
  
  Sci Eng Ethics
  
  Volume: (On line) Issue: 4 Pages: 1473-86
- DOI
  10.1007/s11948-011-9321-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365
[Journal Article] Influence of Intraarticular Neutrophils on the Effects of Photodynamic Therapy for Murine MRSA Arthritis2010
- Author(s)
  Tanaka, M., Kinoshita, M., Yoshihara, Y., Shinomiya, N., Seki, S., Nemoto, K., Morimoto, Y
- Journal Title
  
  Photochem. Photobiol
  
  Volume: 86 Pages: 403-409
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Pretreatment with ascorbic acid prevents lethal gastrointestinal syndrome in mice receiving a massive amount of radiation2010
- Author(s)
  Yamamoto, T., Kinoshita, M., Shinomiya, N., Hiroi, S., Sugasawa, H., Matsushita, Y., Majima, T., Saitoh, D., Seki, S
- Journal Title
  
  J. Radiat. Res.
  
  Volume: 51 Pages: 145-156
- NAID
  10025914571
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Linezolid and vancomycin decrease the therapeutic effect of methylene blue-photodynamic therapy in a mouse model of MRSA bacterial arthritis
- Author(s)
  Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hamblin M
- Journal Title
  
  Photochem. Photobiol
- Data Source
  KAKENHI-PROJECT-22592027
[Presentation] 臨床診断された痛風患者のみによる病型分類別のゲノムワイド関連解析および遺伝率2024
- Author(s)
  中山昌喜, 豊田優, 中杤昌弘, 河村優輔, 中岡博史, 市田公美, 高田龍平, 清水聖子, 清水徹, 大山博司, 大山恵子, 長瀬満夫, 日高雄二, 高田雄三, 四ノ宮成祥, 松尾洋孝
- Organizer
  第57回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 女性の血清尿酸値上昇に及ぼすABCG2機能低下の影響の定量的解析～閉経・肥満・飲酒・加齢との比較～2024
- Author(s)
  三好優香, 中島宏, 中山昌喜, 橋本逸美, 河村優輔, 清水聖子, 豊田優, 上野美紀, 早野貴美子, 四ノ宮成祥, 角田正史, 松尾洋孝
- Organizer
  第69回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] コーヒー摂取の習慣は血清尿酸値とは相関せずに痛風リスクを減少させる：日欧の人種集団におけるメンデルランダム化解析より2024
- Author(s)
  大西まなみ, 白井雄也, 野原悠希, 中山昌喜, 河村優輔, 豊田優, 染谷真澄, 中杤昌弘, 清水聖子, 四ノ宮成祥, 岡田随象, 松尾洋孝
- Organizer
  第69回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 家族性若年性高尿酸血症性腎症（FJHN, ADTKD-UMOD）と腎性低尿酸血症が合併した一例2024
- Author(s)
  中山昌喜, 清水聖子, 豊田優, 横尾隆, 四ノ宮成祥, 松尾洋孝
- Organizer
  第57回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 閉経とABCG2機能低下が女性の血清尿酸値上昇に及ぼす影響の検討2024
- Author(s)
  三好優香, 中山昌喜, 河村優輔, 清水聖子, 豊田優, 上野美紀, 早野貴美子, 四ノ宮成祥, 松尾洋孝
- Organizer
  第57回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 尿酸の体内動態制御におけるOAT10の生理学的重要性と薬理学的インパクト2023
- Author(s)
  豊田優, 高田龍平, 河村優輔, 中山昌喜, 森本渓音, 清水聖子, 棚橋勇紀, 田村高志, 近藤高明, 加藤泰文, 市田公美, 鈴木洋史, 小林靖, 四ノ宮成祥, 松尾洋孝
- Organizer
  第41回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 脳科学研究に潜むDual Useの側面2023
- Author(s)
  四ノ宮成祥
- Organizer
  ゲノム問題検討会議セミナー『脳科学技術／ブレイン・マシン・インターフェイス（BMI）と社会』
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] デュアルユース：漫画ストーリーからのバックキャスティング2023
- Author(s)
  四ノ宮成祥
- Organizer
  科学技術社会論学会第22回年次研究大会，オーガナイズドセッション「フィクションはデュアルユースの夢/悪夢を見せるか？」
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] OAT10は生理学的に重要な尿酸再吸収輸送体である2023
- Author(s)
  豊田優, 河村優輔, 中山昌喜, 清水聖子, 川口真, 高田雄三, 市田公美, 四ノ宮成祥, 松尾洋孝, 高田龍平, （以下、非学会員共同演者）, 森本渓音, 棚橋勇紀, 田村高志, 近藤高明, 加藤泰文, 鈴木洋史, 小林靖
- Organizer
  第56回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] デュアルユース性やDURC（Dual Use Research of Concern）とはどういうものなのか?2023
- Author(s)
  四ノ宮成祥
- Organizer
  第一部：社会、アート、ガバナンス、職業倫理．クロージング・フォーラム『デュアルユース研究を通してつなげる・つながる』
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] Considerations on the pros and cons of generating enhanced potentially pandemic pathogens (ePPPs) through gain-of-function (GOF) research2023
- Author(s)
  Nariyoshi Shinomiya, Jusaku Minari, Go Yoshizawa
- Organizer
  SPT2023, 23rd Biennial Conference in Tokyo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] コーヒーは尿酸値と独立して痛風リスクを減少させる：日欧の人種集団におけるメンデルランダム化解析より2023
- Author(s)
  中山昌喜, 白井雄也, 河村優輔, 豊田優, 中杤昌弘, 清水聖子, 四ノ宮成祥, 岡田随象, 松尾洋孝
- Organizer
  第33回日本疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] B2-1公募シンポジウム　先端生命科学を取り巻くデュアルユース性への対応にむけて2023
- Author(s)
  三成寿作、四ノ宮成祥
- Organizer
  第35回日本生命倫理学会年次大会
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] 尿酸輸送体遺伝子ABCG2の多型解析を通したゲノム個別化看護の可能性についての検討2023
- Author(s)
  早野貴美子, 上野美紀, 中山昌喜, 杉山諒, 鳥羽美帆, 豊田優, 花岡海虹, 水田奈々子, 清水聖子, 河村優輔, 四ノ宮成祥, 松尾洋孝, （以下、非学会員共同演者）, 内田香里, 室円, 三好優香, 橋本逸美, 中島宏, 郡司俊樹, 菊池理園, 若井建志
- Organizer
  第56回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] ePPPをめぐるGOF研究のあり方（What Should GOF Research on ePPP be?）2023
- Author(s)
  四ノ宮成祥
- Organizer
  「細胞を創る」研究会16.0　Session 5：『つくる研究』の安心・安全―デュアルユースの観点から
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] Physiological and pharmacological characterization of OAT10/SLC22A13, a urate re-absorber in the kidney2023
- Author(s)
  Takada, T., Toyoda Y., Kawamura Y., Nakayama A., Morimoto K., Shimizu S., Shinomiya N., Kobayashi Y., Ichida K., Matsuo H
- Organizer
  The 20th Symposium on Purine and Pyrimidine Metabolism in Man (PP23)
- Invited
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] コーヒー摂取の習慣は血清尿酸値とは無関係に痛風リスクを減らす：日欧の人種集団におけるゲノムワイド関連解析の結果を活用したメンデルランダム化解析より2023
- Author(s)
  河村優輔, 中山昌喜, 豊田優, 中杤昌弘, 清水聖子, 四ノ宮成祥, 岡田随象, 松尾洋孝, （以下、非学会員共同演者）, 白井雄也
- Organizer
  第56回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 第1部　デュアルユースのサイエンス2023
- Author(s)
  四ノ宮成祥
- Organizer
  サイエンスアゴラ「デュアルユースと社会とわたし　Dual-use, society and myself」
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] コーヒーは尿酸値とは無関係に痛風リスクを減らす：ゲノムワイド関連解析の結果を用いたメンデルランダム化解析から2022
- Author(s)
  中山昌喜, 白井雄也, 河村優輔, 豊田優, 中杤昌弘, 清水聖子, 四ノ宮成祥, 岡田随象, 松尾洋孝
- Organizer
  第40回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 腎臓における尿酸輸送体としてのOAT10の分子生理学的理解2022
- Author(s)
  豊田優, 高田龍平, 河村優輔, 中山昌喜, 森本渓音, 清水聖子, 四ノ宮成祥, 小林靖, 松尾洋孝
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 日本人集団３万人における尿酸再吸収輸送体遺伝子URAT1/SLC22A12の機能消失型変異がもたらす影響についての臨床遺伝学的検討2022
- Author(s)
  中山昌喜, 河村優輔, 豊田優, 清水聖子, 染谷真澄, 田中里沙, 森友理乃, 今給黎敏彦, 岩澤聡子, 中島宏, 角田正史, 伊藤敬一, 有澤孝吉, 嶽崎俊郎, 田中恵太郎, 高田龍平, 市田公美, 若井建志, 四ノ宮成祥, 松尾洋孝
- Organizer
  第16回トランスポーター研究会年会/JTRA2022
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 先進生命科学技術としての遺伝子ドライブとデュアルユース問題2022
- Author(s)
  四ノ宮成祥
- Organizer
  科学技術社会論学会第21回年次大会オーガナイズドセッション「遺伝子ドライブを巡るELSIとDURC」
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] NGS-HiCEP法による腎細胞癌の腫瘍マーカー候補の同定2022
- Author(s)
  北村陽典、中山昌喜、辻田裕二郎、川口真、高尾幹也、清水聖子、中岡博史、岩屋啓一、斎藤俊行、豊田優、河村優輔、高田雄三、湯野川春信、荒木良子、安倍真澄、津田均、四ノ宮成祥、松尾洋孝、伊藤敬一
- Organizer
  第31回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-20K21740
[Presentation] 尿中尿酸排泄率と血清尿酸値の特異的な分布パターンに基づく腎性低尿酸血症の実践的な診断モデルの提案：日本人大規模集団における臨床遺伝疫学的解析より2022
- Author(s)
  染谷真澄, 河村優輔, 中山昌喜, 清水聖子, 豊田優, 鳥羽美帆, 竹田圭吾, 菊池理園, 中嶌真由子, 川口真, 鈴木聡子, 岩澤聡子, 中島宏, 角田正史, 市田公美, 若井建志, 松尾恵太郎, 四ノ宮成祥, 松尾洋孝
- Organizer
  第68回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 腎性低尿酸血症の原因遺伝子URAT1/SLC22A12の日本人30,685名における臨床遺伝学的解析：実際的診断に向けて2022
- Author(s)
  河村優輔, 中山昌喜, 清水聖子, 豊田優, 染谷真澄, 小田悠太, 鳥羽美帆, 川口真, 鈴木聡子, 岩澤聡子, 中島宏, 高田龍平, 角田正史, 有澤幸吉, 嶽崎俊郎, 田中恵太郎, 市田公美, 若井建志, 四ノ宮成祥, 松尾洋孝
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] NGS-HiCEP法による淡明型腎細胞癌・膵管腺癌の腫瘍マーカー候補の同定2022
- Author(s)
  北村陽典、中山昌喜、辻田裕二郎、川口真、高尾幹也、清水聖子、岩屋啓一、河村優輔、豊田優、津田均、四ノ宮成祥、岸庸二、伊藤敬一、松尾洋孝
- Organizer
  第6回Liquid Biopsy研究会
- Data Source
  KAKENHI-PROJECT-20K21740
[Presentation] Clinico-genetics analyses of gout and urate: Recent progresses from Japan2022
- Author(s)
  H. Matsuo, Y. Shirai, Y. Kawamura, Y. Toyoda, M. Nakatochi, A. Nakayama, S. Shimizu, T. Takada, K. Ichida, N. Shinomiya, Y. Okada
- Organizer
  Asia-Pacific Gout Consortium 5th Annual Meeting/12th Oriental gout symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] Mendelian randomization analyses revealed that coffee consumption reduces gout risk independently of serum uric acid levels2022
- Author(s)
  A. Nakayama, Y. Shirai, Y. Kawamura, Y. Toyoda, M. Nakatochi, S. Shimizu, N. Shinomiya, Y. Okada, H. Matsuo
- Organizer
  European Crystal Network Workshop 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] OAT10は腎臓に発現する生理的に重要な尿酸輸送体である2022
- Author(s)
  豊田優, 高田龍平, 河村優輔, 中山昌喜, 森本渓音, 清水聖子, 藤原慎, 鳥羽美帆, 菊池理園, 四ノ宮成祥, 小林靖, 松尾洋孝
- Organizer
  第16回トランスポーター研究会年会/JTRA2022
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 痛風・高尿酸血症の分子病態の解明に向けて:ゲノムワイド関連解析（GWAS）等を通じた遺伝統計学的解析2021
- Author(s)
  松尾洋孝, 高田龍平, 中杤昌弘, 中山昌喜, 大山博司, 長瀬満夫, 日高雄二, 清水徹, 岡田随象, 市田公美, 四ノ宮成祥
- Organizer
  第54回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 先進生命科学技術のデュアルユース問題と倫理規範の在り方2021
- Author(s)
  四ノ宮成祥、三成寿作（オーガナイザー）
- Organizer
  第33回日本生命倫理学会年次大会
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] About the Tianjin Biosecurity Guidelines for Codes of Conduct for Scientists2021
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  Biological Weapons Convention, Meeting of Experts on Review of Developments in the Field of Science and Technology Related to the Convention (MX2)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] NGS-HiCEP identifies candidate tumor markers in clear cell renal cell carcinoma and pancreatic ductal adenocarcinoma.2021
- Author(s)
  Yosuke Kitamura, Akiyoshi Nakayama, Yujiro Tsujita, Makoto Kawaguchi, Mikiya Takao, Seiko Shimizu, Keiichi Iwaya, Yusuke Kawamura, Yu Toyoda, Hitoshi Tsuda, Nariyoshi Shinomiya, Yoji Kishi, Keiichi Ito, Hirotaka Matsuo
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20K21740
[Presentation] Clinico-genetic analyses of gout/hyperuricemia and hypouricemia: Recent progress from Japan2021
- Author(s)
  Matsuo H, Takada T, Nakayama A, Toyoda Y, Kawamura Y, Shimizu S, Nakatochi M, Shirai Y, H. S, Shinomiya N, Ichida K, Okada Y.
- Organizer
  11th Oriental Gout Forum and 5th Asia-Pacific Gout Consortium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 病型特異的な痛風関連遺伝子と適応進化の評価：臨床診断された痛風症例のゲノムワイド関連解析から2021
- Author(s)
  中山昌喜, 中杤昌弘, 河村優輔, 山本健, 中岡博史, 清水聖子, 小山晃英, 栗木清典, 大山博司, 島ノ江千里, 釜野桜子, 前原一輝, 桐原真奈, 嶽崎俊郎, 松尾恵太郎, 鈴木貞夫, 若井建志, 岡田随象, 四ノ宮成祥, 松尾洋孝
- Organizer
  第31回日本疫学会学術総会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] HiCEP法と次世代シークエンシングを併用した膵癌マーカーの同定2021
- Author(s)
  前原一輝, 高尾幹也, 松尾洋孝, 荒木良子, 清水聖子, 中山昌喜, 瀧端康博, 永生高広, 北村陽典, 川口真, 河村優輔, 森友理乃, 田中里沙, 安倍真澄, 伊藤敬一, 四ノ宮成祥, 岸庸二
- Organizer
  第66回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-20K21740
[Presentation] 痛風・高尿酸血症の国際共同ゲノム解析に向けて2021
- Author(s)
  松尾洋孝, 白井雄也, 中山昌喜, 中杤昌弘, 清水聖子, 河村優輔, 高田龍平, 市田公美, 四ノ宮成祥, 岡田随象
- Organizer
  第65回日本リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] About the recommendation of Science and Technology (S&T) Advisory Process from the Federation of American Scientists (FAS)2021
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  Biological Weapons Convention, Meeting of Experts on Review of Developments in the Field of Science and Technology Related to the Convention (MX2)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] Recent findings in clinico-genetics analyses for clinically-defined gout2021
- Author(s)
  Matsuo H, Nakatochi M, Nakayama A, Kawamura Y, Toyoda Y, Shimizu S, Takada T, Ichida K, Shinomiya N, Okada Y
- Organizer
  European Crystal Network
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 現在懸念されているバイオのリスク2020
- Author(s)
  四ノ宮成祥
- Organizer
  第18回川越市市民健康講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] Development of a gene expression database of pancreatic ductal adenocarcinoma cases by NGS-combined HiCEP to identify tumor markers2020
- Author(s)
  Takao M, Araki R, Shimizu S, Kawaguchi M, Akiyoshi Nakayama, Kitamura Y, Kawamura Y, Maehara K, Abe M, Ito K, Hoshikawa M, Yamamoto J, Kishi Y, Shinomiya N,
- Organizer
  American Association for Cancer Research (AACR) 2020.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] 合成生物学がもたらすデュアルユース問題について．公募シンポジウムⅡ「ゲノム合成時代における先端生命科学技術とバイオセキュリティ」2020
- Author(s)
  四ノ宮成祥
- Organizer
  日本生命倫理学会第32回年次大会
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] 生物テロに対する取り組み2020
- Author(s)
  四ノ宮成祥
- Organizer
  危機管理産業展(RISCON TOKYO)2020・テロ対策特殊装備(SEECAT)’20 テーマ「ソフトターゲットに対する取り組み」(主催：東京都・東京ビッグサイト)
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] Development of a gene expression database of pancreatic ductal adenocarcinoma cases by NGS-combined HiCEP to identify tumor markers2020
- Author(s)
  Takao M, Matsuo H, Araki R, Shimizu S, Kawaguchi M, Nakayama A, Kitamura Y, Kawamura Y, Maehara K, Abe M, Ito K, Hoshikawa M, Yamamoto J, Kishi Y, Shinomiya N
- Organizer
  American Association for Cancer Research (AACR) 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21740
[Presentation] 合成生物学の実態とその応用　－生命科学の新たな展開と市民社会－2020
- Author(s)
  四ノ宮成祥
- Organizer
  合成生物学によるウイルス作成とデュアルユース問題．ゲノム問題検討会議　Zoomフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] 次世代シークエンシングの併用によるHiCEP法（NGS-HiCEP法）の開発―腎癌組織の網羅的遺伝子発現データベースの構築と腎癌マーカーの同定2020
- Author(s)
  前原一輝, 川口真, 松尾洋孝, 荒木良子, 清水聖子, 高尾幹也, 中山昌喜, 北村陽典, 辻田裕二郎, 河村優輔, 堀江美音, 藤原慎, 湯野川春信, 安倍真澄, 伊藤敬一, 四ノ宮成祥
- Organizer
  第38回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21740
[Presentation] Subtype Genome-Wide Meta-Analyses of Clinically-Defined Gout Revealed Multiple Subtype-Specific Gout Loci and Enrichment of Selection Pressure on ABCG2 and ALDH22020
- Author(s)
  Kawamura Y, Nakayama A, Nakatochi M, Yamamoto K, Nakaoka H, Shimizu S, Maehara K, Kirihara M, Koyama T, Hishida A, Shimizu T, Ooyama H, Nagase M, Shirai Y, Toyoda Y, Takada T, Kamatani Y, Ichida K, Wakai K, Inoue I, Okada Y, Shinomiya N, Matsuo H.
- Organizer
  22nd Asia Pacific League of Associations for Rheumatology (APLAR 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] URAT2/OAT10の機能低下型変異は血清尿酸値と痛風リスクの低下に寄与する2020
- Author(s)
  桐原真奈, 東野俊英, 森本渓音, 中岡博史, 豊田優, 河村優輔, 清水聖子, 藤原慎, 堀江美音, 中山昌喜, 大山博司, 清水徹, 田村高志, 鈴木洋史, 井ノ上逸朗, 四ノ宮成祥, 高田龍平, 松尾洋孝
- Organizer
  第66回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] URAT2/OAT10の機能低下型ミスセンス変異は血清尿酸値と痛風リスクを共に低下させる2020
- Author(s)
  桐原真奈, 東野俊英, 森本渓音, 中岡博史, 豊田優, 河村優輔, 清水聖子, 田中里沙, 森友理乃, 中山昌喜, 大山博司, 清水徹, 田村高志, 鈴木洋史, 井ノ上逸朗, 四ノ宮成祥, 高田龍平, 松尾洋孝
- Organizer
  第38回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] HiCEP法と次世代シークエンシングを併用した腎細胞癌マーカーの同定2020
- Author(s)
  青柳有香, 川口真, 松尾洋孝, 荒木良子, 清水聖子, 高尾幹也, 中山昌喜, 桐原真奈, 北村陽典, 湯野川春信, 安倍真澄, 四ノ宮成祥, 伊藤敬一.
- Organizer
  第65回防衛衛生学会. (東京)
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] NGS-HiCEP法を活用した膵癌発現データベースの構築と膵癌マーカー候補遺伝子の探索.2020
- Author(s)
  高尾幹也, 松尾洋孝, 荒木良子, 清水聖子, 中岡博史, 川口真, 中山昌喜, 河村優輔, 湯野川春信, 安倍真澄, 伊藤敬一, 星川真有美, 山本順司, 岸庸二, 四ノ宮成祥.
- Organizer
  第30回日本疫学会学術総会. (京都)
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] Incorporation of DURC concept into the code of conduct2020
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  Biological Weapons Convention, 2020 Meeting of Experts: MX2 pre-meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] 尿酸トランスポーターURAT2/OAT10の機能低下は血清尿酸値および痛風リスクを低下させる2020
- Author(s)
  田中里沙, 東野俊英, 森本渓音, 中岡博史, 豊田優, 河村優輔, 清水聖子, 桐原真奈, 前原一輝, 中山昌喜, 大山博司, 清水徹, 田村高志, 鈴木洋史, 井ノ上逸朗, 四ノ宮成祥, 高田龍平, 松尾洋孝
- Organizer
  第5回トランスポーター研究会関東部会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 現在懸念されているバイオのリスク2020
- Author(s)
  四ノ宮成祥
- Organizer
  第18回川越市市民健康講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] HiCEP法と次世代シークエンシングを併用した膵癌マーカーの同定2020
- Author(s)
  前原一輝, 高尾幹也, 松尾洋孝, 荒木良子, 清水聖子, 中山昌喜, 瀧端康博, 永生高広, 北村陽典, 川口真, 河村優輔, 森友理乃, 田中里沙, 安倍真澄, 伊藤敬一, 四ノ宮成祥, 岸庸二
- Organizer
  第66回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] 次世代シークエンシングの併用によるHiCEP法（NGS-HiCEP法）の開発―腎癌組織の網羅的遺伝子発現データベースの構築と腎癌マーカーの同定2020
- Author(s)
  前原一輝, 川口真, 松尾洋孝, 荒木良子, 清水聖子, 高尾幹也, 中山昌喜, 北村陽典, 辻田裕二郎, 河村優輔, 堀江美音, 藤原慎, 湯野川春信, 安倍真澄, 伊藤敬一, 四ノ宮成祥
- Organizer
  第38回日本ヒト細胞学会学術集会(高知)
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] Identification of candidate tumor marker genes for pancreatic ductal adenocarcinoma tissue by NGS-HiCEP method2020
- Author(s)
  Takao M, Matsuo H, Shimizu S, Kitamura Y, Kawaguchi M, Nakayama A, Kawamura Y, Ito K, Kishi Y, Shinomiya N
- Organizer
  日本癌学会, 2020
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] 「高知が生んだ研究者が語る細胞について知ろう：人は細胞から出来ている」2020
- Author(s)
  四ノ宮成祥
- Organizer
  生命の不思議とゲノム研究の課題第38回日本ヒト細胞学会学術集会市民公開講座
- Invited
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] 生物兵器転用が懸念される先進生命科学技術剤2020
- Author(s)
  四ノ宮成祥
- Organizer
  「ヒューマン防護システム研究部会」第14回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] 生物兵器転用が懸念される先進生命科学技術2020
- Author(s)
  四ノ宮成祥
- Organizer
  「ヒューマン防護システム研究部会」第14回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] Subtype genome-wide meta-analyses of gout: novel gout risk loci and enrichment of selection pressure on ABCG2 and ALDH22020
- Author(s)
  Kawamura Y, Nakayama A, Nakatochi M, Yamamoto K, Nakaoka H, Shimizu S, Kirihara M, Shimizu T, Ooyama H, Shirai Y, DanjohI, Hosomichi K, Kamatani Y, Kubo M, Ichida K, Wakai K, Inoue I, Okada Y, Shinomiya N, Matsuo H.
- Organizer
  日本人類遺伝学会第65回大会
- Data Source
  KAKENHI-PROJECT-20H00566
[Presentation] 合成生物学がもたらすデュアルユース問題について (公募シンポジウムⅡ 「ゲノム合成時代における先端生命科学技術とバイオセキュリティ」)2020
- Author(s)
  四ノ宮成祥
- Organizer
  日本生命倫理学会第32回年次大会
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] 合成生物学によるウイルス作成とデュアルユース問題2020
- Author(s)
  四ノ宮成祥
- Organizer
  ゲノム問題検討会議　Zoomフォーラム「合成生物学の実態とその応用－生命科学の新たな展開と市民社会－」
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] 複合災害対応に向けての考察－過去の生物災害などの事例に学ぶ－ How should we respond to complex disasters? － Lessons learned from the past experiences2020
- Author(s)
  四ノ宮成祥
- Organizer
  第2回東日本国際大学健康社会戦略研究所国際シンポジウム「東日本大震災と原発事故からの10年」
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] Incorporation of DURC concept into the code of conduct．Biological Weapons Convention2020
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  2020 Meeting of Experts: MX2 pre-meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] Identification of candidate tumor marker genes for pancreatic ductal adenocarcinoma tissue by NGS-HiCEP method2020
- Author(s)
  Takao M, Matsuo H, Shimizu S, Kitamura Y, Kawaguchi M, Nakayama A, Kawamura Y, Ito K, Kishi Y, Shinomiya N
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21740
[Presentation] 特別講演「Meeting with Met癌遺伝子Metとその機能制御」2020
- Author(s)
  四ノ宮成祥
- Organizer
  第38回日本ヒト細胞学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] The use of NGS-HiCEP to build an extensive renal cell carcinoma gene expression database for identifying tumor markers2020
- Author(s)
  Shimizu S, Matsuo H, Kawaguchi M, Nakayama A, Takao M, Kitamura Y, Tsujita Y, Kawamura Y, Ito K, Shinomiya N
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21740
[Presentation] 生命の不思議とゲノム研究の課題2020
- Author(s)
  四ノ宮成祥
- Organizer
  第38回日本ヒト細胞学会学術集会市民公開講座「高知が生んだ研究者が語る細胞について知ろう：人は細胞から出来ている」
- Data Source
  KAKENHI-PROJECT-20K20493
[Presentation] 次世代シークエンサーを併用したHiCEP法による腎癌の遺伝子発現データベースの構築と腎癌マーカーの同定2019
- Author(s)
  川口真、松尾洋孝、荒木良子、清水聖子、高尾幹也、中山昌喜、湯野川春信、安倍真澄、四ノ宮成祥、伊藤敬一
- Organizer
  第28回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] 最近の生物剤の動向2019
- Author(s)
  四ノ宮成祥
- Organizer
  第５回「生物テロ・バイオ災害対策担当者養成講習会」
- Invited
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] 公募シンポジウムⅤ「ゲノム編集技術が社会に及ぼす影響と食・農分野における課題」ゲノム編集技術が有する科学技術上のデュアルユース性について2019
- Author(s)
  四ノ宮成祥
- Organizer
  日本生命倫理学会第31回年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] HiCEP法と次世代シークエンサーを併用した腎癌組織の遺伝子発現データベースの構築と腎癌マーカーの同定2019
- Author(s)
  川口真、松尾洋孝、荒木良子、清水聖子、高尾幹也、中山昌喜、北村陽典、湯野川春信、安倍真澄、四ノ宮成祥、伊藤敬一
- Organizer
  第107回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] Biological risk assessment of leading-edge life science and its management2019
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  Biological Weapons Convention 2019 Meeting of Experts: MX2
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] HiCEP法と次世代シークエンサーを併用した新規発現解析法による膵癌の遺伝子発現データベースの構築と膵癌マーカーの同定.2019
- Author(s)
  高尾幹也, 松尾洋孝, 清水聖子, 川口真, 中山昌喜, 河村優輔, 伊藤敬一, 星川真有美, 山本順司, 岸庸二, 四ノ宮成祥.
- Organizer
  第78回日本癌学会学術総会. (京都)
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] Invited Lecture 3：Molecular mechanisms of hyperbaric stress in deep diving2019
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  The 4th Conference of APUHMS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] テロを含むバイオ災害の可能性と対策2019
- Author(s)
  四ノ宮成祥
- Organizer
  危機管理フォーラム2019 「テロ・災害と医療対策」
- Invited
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] ゲノム編集技術が有する科学技術上のデュアルユース性について2019
- Author(s)
  四ノ宮成祥
- Organizer
  日本生命倫理学会第31回年次大会公募シンポジウムⅤ
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] HiCEP法と次世代シークエンサーを併用した新規発現解析法による膵癌の遺伝子発現データベースの構築と膵癌マーカーの同定.2019
- Author(s)
  高尾幹也, 松尾洋孝, 荒木良子, 清水聖子, 川口真, 中山昌喜, 河村優輔, 青柳有香, 前原一輝, 湯野川春信, 安倍真澄, 伊藤敬一, 岸庸二, 四ノ宮成祥.
- Organizer
  第37回日本ヒト細胞学会学術集会. (三鷹)
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] 生命科学、合成生物学とバイオセキュリティ2019
- Author(s)
  四ノ宮成祥
- Organizer
  外務省「外交・安全保障調査研究事業費補助金（調査研究事業）」に係る研究会合「技術革新がもたらす安全保障環境の変容と我が国の対応」
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] 先進生命科学技術がもたらすデュアルユース問題2019
- Author(s)
  四ノ宮成祥
- Organizer
  ゲノム問題検討会議シンポジウム　現代科学技術と人権「科学技術は私達生活にどのように関わってくるのか」
- Invited
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] デュアルユースが懸念される研究とその教育2019
- Author(s)
  四ノ宮成祥
- Organizer
  第６回バイオセキュリティ研究会
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] Development of a gene expression database of renal cell carcinoma cases by NGS-combined HiCEP to identify tumor markers.2019
- Author(s)
  川口真、松尾洋孝、荒木良子、清水聖子、高尾幹也、中山昌喜、北村陽典、安倍真澄、伊藤敬一、四ノ宮成祥
- Organizer
  2019年アメリカ癌研究会年次総会
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] バイオテクノロジーとデュアルユース問題2019
- Author(s)
  四ノ宮成祥
- Organizer
  「軍事研究を哲学する」第3回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] 最近の生物剤の動向2019
- Author(s)
  四ノ宮成祥
- Organizer
  シンポジウム「緊迫する国際情勢とCBRN脅威に対する備え」
- Invited
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] HiCEP法と次世代シークエンサーを併用した腎癌組織の遺伝子発現データベースの構築と腎癌マーカーの同定.2019
- Author(s)
  川口真, 松尾洋孝, 荒木良子, 清水聖子, 高尾幹也, 中山昌喜, 北村陽典, 湯野川春信, 安倍真澄, 四ノ宮成祥, 伊藤敬一.
- Organizer
  第107回日本泌尿器科学会総会. (名古屋)
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] Development of the gene expression database of pancreatic ductal adenocarcinoma cases by NGS combined HiCEP method to identify the tumor markers.2019
- Author(s)
  Takao M, Matsuo H, Araki R, Shimizu S, Kawaguchi M, Nakayama A, Yunokawa H, Abe M, Ito K, Hoshikawa M, Aosasa S, Yamamoto J, Shinomiya N.
- Organizer
  The 31st Meeting of? Japanese Society of Hepato-Biliary-Pancreatic Surgery. (高松)
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] 新興生命科学技術と安全保障2019
- Author(s)
  四ノ宮成祥
- Organizer
  「安全保障と新興技術」研究会
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] デュアルユースが懸念される研究とその教育2019
- Author(s)
  四ノ宮成祥
- Organizer
  第19回日本バイオセーフティ学会シンポジウム２
- Invited
- Data Source
  KAKENHI-PROJECT-18K18480
[Presentation] ADH1B とALDH2 の機能低下型多型は痛風発症と関連する.2018
- Author(s)
  小松　眞子、松尾　洋孝、崎山　真幸、川口　真、中山　昌喜、長尾　優太郎、内藤　真理子、川合　紗世、中島　宏、櫻井　裕、清水　徹、大山　博司、四ノ宮　成祥
- Organizer
  第28回日本疫学会学術総会
- Data Source
  KAKENHI-PROJECT-17K19863
[Presentation] バイオセキュリティーに関する話題提供2018
- Author(s)
  四ノ宮成祥
- Organizer
  「ゲノム構築の社会産業基盤を作り上げていくための産学連携」を考える会
- Invited
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] Biosecurity issues in Japan2018
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  Workshop on the Governance of Emerging BioDesign Technologies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] Cutting Edge Life Science and Dual Use Issues - How Should We Have a Dialogue with Society?2018
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  Biological Weapons Convention 2018 Meeting of Experts: MX2
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] Preparedness for Biorisk, Including Bioterrorism, and Health Emergencies in Asia2018
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  Third U.S.-Japan Global Health Dialogue
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] Biosecurity issues in Japan2018
- Author(s)
  Shinomiya N
- Organizer
  Workshop on the Governance of Emerging BioDesign Technologies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] ゲノム合成技術の出現　－合成生物学の進展とそのELSI－2018
- Author(s)
  四ノ宮成祥
- Organizer
  第30回日本生命倫理学会年次大会公募シンポジウム IV
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] Development of the gene expression database of renal cell carcinoma cases to identify the tumor markers.2018
- Author(s)
  川口真、松尾洋孝、清水聖子、高尾幹也、中山昌喜、山本順司、伊藤敬一、四ノ宮成祥
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02685
[Presentation] Basic fibroblast growth factor-loaded PLGA nanosheet promotes wound healing of refractory skin lesions.2017
- Author(s)
  Kinoshita M, Shinomiya N, Aoki S, Kiyosawa T, Seki S
- Organizer
  CBD S&T
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] 尿酸トランスポーターABCG2を介したヒト腸管からの尿酸排泄の証明：小腸上皮障害のマーカーとしての血清尿酸値の重要性2017
- Author(s)
  松尾洋孝、大山恵子、崎山真幸、高田龍平、中山昌喜、川口真、東野俊英、大山博司、市田公美、藤森新、四ノ宮成祥
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] アルデヒド脱水素酵素ALDH2遺伝子のミスセンス変異rs671は痛風発症リスクを低下させる2017
- Author(s)
  崎山真幸, 松尾洋孝, 中山昌喜, 大山博司, 清水徹, 四ノ宮成祥
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] 革新的研究開発推進プログラムImPACT共催　セッション2: ゲノム合成時代のバイオセキュリティ・セーフティ　病原体の人工合成とバイオセキュリティ問題2017
- Author(s)
  四ノ宮成祥
- Organizer
  細胞を創る会10.0
- Invited
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] PDZK1の一塩基多型は痛風の発症リスクと関連する。2017
- Author(s)
  東野俊英、松尾洋孝、崎山真幸、中山昌喜、高田龍平、河村優輔、川口真、高田雄三、大山博司、四ノ宮成祥
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] Correlation between c-Met and ALDH1 contributes to the survival and tumor-sphere formation of ALDH1 positive breast cancer stem cells and predicts poor clinical outcome in breast cancer2017
- Author(s)
  野崎優香、多森翔馬、稲田将大、片山鈴花、中根裕美、南島治、小野寺祐佳、阿部真実、椎名將太、田村渓、小玉大地、佐藤圭子、原泰志安部良、髙澤涼子、吉森篤史、四ノ宮成祥、田沼靖一、秋本和憲
- Organizer
  第61回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] 公募シンポジウム IV　ゲノム編集をめぐる公共倫理と新たなガバナンス（オーガナイザー）2017
- Author(s)
  四ノ宮成祥
- Organizer
  第29回日本生命倫理学会年次大会
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] URAT1/SLC22A12遺伝子の機能消失型変異が血清尿酸値および痛風・高尿酸血症の発症に与える影響2017
- Author(s)
  崎山真幸、松尾洋孝、清水聖子、中山昌喜、東野俊英、高田龍平、市田公美、大山博司、清水徹、四ノ宮成祥
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] 分子遺伝疫学解析によるヒト腸管からの尿酸排泄の証明：尿酸値は小腸上皮障害のマーカーとなる2017
- Author(s)
  赤司藍理、松尾洋孝、角田知之、大山恵子、崎山真幸、十河剛、中山昌喜、川口真、東野俊英、若井建志、大山博司、穂苅量太、乾あやの、四ノ宮成祥
- Organizer
  第27回日本疫学会学術総会
- Place of Presentation
  甲府
- Year and Date
  2017-01-25
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] URAT1/SLC22A12遺伝子の機能消失型変異が血清尿酸値および痛風・高尿酸血症の発症に与える影響2017
- Author(s)
  崎山真幸、松尾洋孝、清水聖子、中山昌喜、東野俊英、高田龍平、市田公美、大山博司、清水徹、四ノ宮成祥
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] ABCG2 physiologically mediates intestinal urate excretion in humans: Serum uric acid as a useful marker for impairment of intestinal epithelium2017
- Author(s)
  Hirotaka Matsuo, Tomoyuki Tsunoda, Keiko Ooyama, Masayuki Sakiyama, Tsuyoshi Sogo, Akiyoshi Nakayama, Makoto Kawaguchi, Airi Akashi, Mako Komatsu, Toshihide Higashino, Kenji Wakai, Hiroshi Ooyama, Kimiyoshi Ichida, Ayano Inui, Nariyoshi Shinomiya
- Organizer
  第94回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] 尿酸トランスポーターABCG2を介したヒト腸管からの尿酸排泄の証明：小腸上皮障害のマーカーとしての血清尿酸値の重要性2017
- Author(s)
  松尾洋孝、大山恵子、崎山真幸、高田龍平、中山昌喜、川口真、東野俊英、大山博司、市田公美、藤森新、四ノ宮成祥
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] Common dysfunctional variants of ABCG2 may contribute to acquired photosensitivity by porphyrin accumulation2017
- Author(s)
  Masayuki Sakiyama1,2,*, Hirotaka Matsuo1, Yuiko Yonekura2, Takahiro Ishikawa2, Akiyoshi Nakayama1, Toshihide Higashino1, Norihiro Fujimoto2, Takahiro Satoh2, Nariyoshi Shinomiya
- Organizer
  日本研究皮膚科学会　第42回年次学術大会・総会
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] Basic fibroblast growth factor-loaded PLGA nanosheet promotes wound healing of refractory skin lesions2017
- Author(s)
  Kinoshita M, Shinomiya N, Aoki S, Kiyosawa T, Seki S.
- Organizer
  CBD S&T
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] 痛風のゲノムワイド関連解析：新規遺伝座を含めた10個の痛風関連遺伝子座の同定2017
- Author(s)
  中山昌喜、松尾洋孝、崎山真幸、高田龍平、清水聖子、東野俊英、河村優輔、川口真、徳増淳美、大山恵子、細山田真、藤森新、横尾隆、細谷龍男、大山博司、清水徹、市田公美、四ノ宮成祥
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] 痛風のゲノムワイド関連解析：新規遺伝座を含めた10個の痛風関連遺伝子座の同定2017
- Author(s)
  中山昌喜、松尾洋孝、崎山真幸、高田龍平、清水聖子、東野俊英、河村優輔、川口真、徳増淳美、大山恵子、細山田真、藤森新、横尾隆、細谷龍男、大山博司、清水徹、市田公美、四ノ宮成祥
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] アルデヒド脱水素酵素ALDH2遺伝子のミスセンス変異rs671は痛風発症リスクを低下させる2017
- Author(s)
  崎山真幸, 松尾洋孝, 中山昌喜, 大山博司, 清水徹, 四ノ宮成祥
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] PDZK1の一塩基多型は痛風の発症リスクと関連する。2017
- Author(s)
  東野俊英、松尾洋孝、崎山真幸、中山昌喜、高田龍平、河村優輔、川口真、高田雄三、大山博司、四ノ宮成祥
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] ヒト腸管からの生理学的な尿酸排泄機構の証明：尿酸値は小腸上皮障害のマーカーとなる2017
- Author(s)
  松尾洋孝、角田知之、大山恵子、崎山真幸、十河剛、中山昌喜、川口真、赤司藍理、小松眞子、東野俊英、若井建志、大山博司、市田公美、乾あやの、四ノ宮成祥
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] ALDH2遺伝子変異rs671は痛風発症リスクを下げる：fine mappingによる痛風関連遺伝子の同定2017
- Author(s)
  棚橋勇輝、松尾洋孝、崎山真幸、中岡博史、山本健、中山昌喜、中村好宏、川合紗世、岡田理恵子、大山博司、清水徹、四ノ宮成祥
- Organizer
  第27回日本疫学会学術総会
- Place of Presentation
  甲府
- Year and Date
  2017-01-25
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] Genetic epidemiological analysis revealed intestinal urate excretion via ABCG2 in human: serum uric acid is a useful marker for impairment of intestinal epithelium2017
- Author(s)
  Akashi A, Matsuo H, Tsunoda T, Ooyama K, Sakiyama M, Sogo T, Nakayama A, Wakai K, Ooyama H, Shinomiya N
- Organizer
  21st International Epidemiological Association (IEA) World Congress of Epidemiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] Genome-Wide Association Study of Clinically-Ascertained Gout and Subtypes Identifies Multiple Susceptibility Loci Including Transporter Genes2017
- Author(s)
  Matsuo H, Nakayama A, Nakaoka H, Yamamoto K, Sakiyama M, Shaukat A, Toyoda Y, Okada Y, Kamatani Y, Nakatochi M, Nakamura T, Takada T, Nakashima H, Shimizu S, Kawaguchi M, Hishida A, Wakai K, Stiburkova B, Pavelka K, Stamp L. K, Dalbeth N, Hosoya T, Kubo M, Ooyama H, Shimizu T, Ichida K, Merriman T. R, Shinomiya N
- Organizer
  2017 American College of Rheumatology / Association for Rheumatology Health Professionals Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] ヒト腸管からの生理学的な尿酸排泄機構の証明：尿酸値は小腸上皮障害のマーカーとなる2017
- Author(s)
  松尾洋孝、角田知之、大山恵子、崎山真幸、十河剛、中山昌喜、川口真、赤司藍理、小松眞子、東野俊英、若井建志、大山博司、市田公美、乾あやの、四ノ宮成祥
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] Medical countermeasures using LPS tolerance to address lethal toxic shock and fatal bacterial sepsis2017
- Author(s)
  Kinoshita M, Shinomiya N, Miyazaki H, Nakashima H, Nakashima M, Seki S.
- Organizer
  CBD S&T
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] ヒト乳癌においてc-Metは癌幹細胞マーカーであるALDH1と共発現し患者の予後不良に関わる2017
- Author(s)
  野崎優香、多森翔馬、稲田将大、片山鈴花、中根裕美、南島治、小野寺祐佳、阿部真実、椎名將太、田村渓、小玉大地、佐藤圭子、原泰志、安部良、髙澤涼子、吉森篤史、四ノ宮成祥、田沼靖一、秋本和憲
- Organizer
  第１回東京理科大学ー横浜市立大学合同シンポジウム
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] GWAS of clinically-ascertained gout and its subtypes identified ten loci that include urate transporter genes.2017
- Author(s)
  Matsuo H, Nakayama A, Nakaoka H, Yamamoto K, Sakiyama M, Shaukat A, Toyoda Y, Okada Y, Kamatani Y, Takada T, Shimizu S, Kawaguchi M, Wakai K, Stiburkova B, Kubo M, Ooyama H, Shimizu T, Ichida K, Merriman TR on behalf of Eurogout Consortium, Shinomiya N
- Organizer
  17th International Purine and Pyrimidine Symposium.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] ALDH2遺伝子変異rs671は痛風発症リスクを下げる：fine mappingによる痛風関連遺伝子の同定2017
- Author(s)
  棚橋勇輝、松尾洋孝、崎山真幸、中岡博史、山本健、中山昌喜、中村好宏、川合紗世、岡田理恵子、大山博司、清水徹、四ノ宮成祥
- Organizer
  第27回日本疫学会学術総会
- Place of Presentation
  甲府
- Year and Date
  2017-01-25
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] Medical countermeasures using LPS tolerance to address lethal toxic shock and fatal bacterial sepsis2017
- Author(s)
  Kinoshita M, Shinomiya N, Miyazaki H, Nakashima H, Nakashima M, Seki S
- Organizer
  CBD S&T
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] 分子遺伝疫学解析によるヒト腸管からの尿酸排泄の証明：尿酸値は小腸上皮障害のマーカーとなる2017
- Author(s)
  赤司藍理、松尾洋孝、角田知之、大山恵子、崎山真幸、十河剛、中山昌喜、川口真、東野俊英、若井建志、大山博司、穂苅量太、乾あやの、四ノ宮成祥
- Organizer
  第27回日本疫学会学術総会
- Place of Presentation
  甲府
- Year and Date
  2017-01-25
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] アルコール代謝に関わるALDH2の遺伝子変異rs671を持つ人は痛風を発症しにくい2016
- Author(s)
  赤司藍理、松尾洋孝、崎山真幸、中岡博史、山本健、中山昌喜、中村好宏、川合紗世、岡田理恵子、大山博司、清水徹、四ノ宮成祥
- Organizer
  第34回ヒト細胞学会学術集会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] Dual use research of concern and the responsible conduct of research2016
- Author(s)
  Shinomiya N
- Organizer
  apan-France Workshop “Thinking and working together: collaborative science at an international scale
- Place of Presentation
  東京
- Year and Date
  2016-03-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] GOF研究問題のこれまでの経緯と議論2016
- Author(s)
  四ノ宮成祥
- Organizer
  第28回日本生命倫理学会年次大会
- Place of Presentation
  大阪府
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] 痛風の早期発症に関連する尿酸トランスポーター遺伝子ABCG2の機能低下型変異はパーキンソン病の発症を遅らせる（最優秀発表賞の受賞）2016
- Author(s)
  赤司藍理、松尾洋孝、富山弘幸、佐竹渉、千葉俊周、尾上祐行、河村優輔、中山昌喜、清水聖子、崎山真幸、舩山学、清水徹、海田賢一、鎌倉惠子、戸田達史、服部信孝、四ノ宮成洋
- Organizer
  第11回トランスポーター研究会年会
- Place of Presentation
  京都
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] バイオセキュリティとデュアルユース問題2016
- Author(s)
  四ノ宮成祥
- Organizer
  第16回日本バイオセーフティ学会総会・学術集会
- Place of Presentation
  さいたま市
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] Genome-wide association study of clinically-ascertained gout identifies multiple risk loci and its association with clinical subtypes2016
- Author(s)
  Airi Akashi,Hirotaka Matsuo, Ken Yamamoto, Hirofumi Nakaoka, Akiyoshi Nakayama, Masayuki Sakiyama, Atsushi Takahashi, Takahiro Nakamura, Yuki Tanahashi, Nobuyuki Hamajima, Ituro Inoue, Michiaki Kubo, Kimiyoshi Ichida, Hiroshi Ooyama, Toru Shimizu, Nariyoshi Shinomiya
- Organizer
  The13th International Congress of Human Genetics
- Place of Presentation
  Kyoto
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] 痛風の早期発症に関連する尿酸トランスポーター遺伝子ABCG2の機能低下型変異はパーキンソン病の発症を遅らせる2016
- Author(s)
  赤司藍理、松尾洋孝、富山弘幸、佐竹渉、千葉俊周、尾上祐行、河村優輔、中山昌喜、清水聖子、崎山真幸、舩山学、清水徹、海田賢一、鎌倉惠子、戸田達史、服部信孝、四ノ宮成洋
- Organizer
  第11回トランスポーター研究会年会
- Place of Presentation
  京都
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] アルコール代謝に関わるALDH2の遺伝子変異rs671を持つ人は痛風を発症しにくい2016
- Author(s)
  赤司藍理、松尾洋孝、崎山真幸、中岡博史、山本健、中山昌喜、中村好宏、川合紗世、岡田理恵子、大山博司、清水徹、四ノ宮成祥
- Organizer
  第34回ヒト細胞学会学術集会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] Genome-wide association study of clinically-ascertained gout identifies multiple risk loci and its association with clinical subtypes2016
- Author(s)
  Airi Akashi,Hirotaka Matsuo, Ken Yamamoto, Hirofumi Nakaoka, Akiyoshi Nakayama, Masayuki Sakiyama, Atsushi Takahashi, Takahiro Nakamura, Yuki Tanahashi, Nobuyuki Hamajima, Ituro Inoue, Michiaki Kubo, Kimiyoshi Ichida, Hiroshi Ooyama, Toru Shimizu, Nariyoshi Shinomiya
- Organizer
  The13th International Congress of Human Genetics
- Place of Presentation
  Kyoto
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] 正規のHBOおよびmild HBOについての基礎的エビデンスの比較2015
- Author(s)
  四ノ宮成祥
- Organizer
  第12回日本臨床高気圧酸素・潜水医学会
- Place of Presentation
  東京
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] Biosecurity Concern Related to Recent Development of Life Science Technology2015
- Author(s)
  Nariyoshi Shinomiya, Manabu Kinoshita, Shuhji Seki, Masamichi Minehata, Malcolm Dando
- Organizer
  2015 Chemical Biological Defense Science & Technology Conference
- Place of Presentation
  St. Louis, USA
- Year and Date
  2015-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] B型肝炎ウイルス誘発性肝細胞癌におけるHGF高発現はMet分子標的治療に対する感受性マーカーとなる2015
- Author(s)
  四ノ宮成祥，岩屋啓一，中山昌喜，崎山真幸，松尾洋孝，守本祐司，吉森篤史，田沼靖一
- Organizer
  第14回日本婦人科がん分子標的研究会
- Place of Presentation
  松本
- Year and Date
  2015-07-17
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] ヒト乳癌ALDHhigh 細胞に対するMET 阻害剤の効果2015
- Author(s)
  稲田将大、片山鈴花、中根裕美、田村渓、松村将史、高澤涼子、原泰志、安部良、吉森篤史、四ノ宮成祥、田沼靖一、秋本和憲
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  千葉県船橋市
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15H04315
[Presentation] 公募シンポジウムⅤ　先端生命科学の動向と研究開発の未来　－脳科学研究倫理の再考とデュアルユース問題－2015
- Author(s)
  四ノ宮　成祥
- Organizer
  第27回日本生命倫理学会年次大会
- Place of Presentation
  千葉市
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-15KT0054
[Presentation] ABCG2 SNP typing by Quenching-Probe method: Effective approach for gout and hyperuricemia risk evaluation2014
- Author(s)
  Sakiyama M, Matsuo H, Takada Y, Nakayama A, Shimizu S, Chiba T, Tatsukawa S, Shichijo Y, Nakashima H, Shimizu T, Sakurai Y, Shinomiya N
- Organizer
  5th FEBS Special Meeting on ABC Proteins
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] ABCG2 SNP typing by Quenching-Probe method: Effective approach for gout and hyperuricemia risk evaluation2014
- Author(s)
  Sakiyama M, Matsuo H, Takada Y, Nakayama A, Shimizu S, Chiba T, Tatsukawa S, Shichijo Y, Nakashima H, Shimizu T, Sakurai Y, Shinomiya N
- Organizer
  5th FEBS Special Meeting on ABC Proteins
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] 光線力学療法の治療効果を抗生物質は抑制する2014
- Author(s)
  姫野尚美,守本祐司,木下学,関修司,四ノ宮成祥
- Organizer
  第87回日本細菌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659599
[Presentation] 抗生剤担持ナノシートを用いた難治性創部細菌感染に対する新規治療戦略2014
- Author(s)
  木下学,齊藤晃広,宮崎裕美,藤枝俊宣,武岡真司,五十嵐正巳,中島正裕,中島弘幸,四ノ宮成祥,関修司
- Organizer
  第87回日本細菌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659599
[Presentation] Dysfunctional ABCG2 by common variants is a major cause of early-onset gout2014
- Author(s)
  Matsuo H, Ichida K, Takada T, Nakayama A, Nakashima H, Nakamura T, Takada Y, Shimizu S, Sakiyama M, Chiba T, Hamajima N, Sakurai Y, Shinomiya N
- Organizer
  5th FEBS Special Meeting on ABC Proteins
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] Dysfunctional ABCG2 by common variants is a major cause of early-onset gout2014
- Author(s)
  Matsuo H, Ichida K, Takada T, Nakayama A, Nakashima H, Nakamura T, Takada Y, Shimizu S, Sakiyama M, Chiba T, Hamajima N, Sakurai Y, Shinomiya N
- Organizer
  5th FEBS Special Meeting on ABC Proteins
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-25293145
[Presentation] 内因性蛍光に基づくがんの定量的病態イメージング2013
- Author(s)
  立石昇一朗、堀内俊克、谷口裕亮、梅津新矢、小倉俊一郎、四ノ宮成祥、守本祐司
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23659599
[Presentation] パネルディスカッション “The role of scientists and their communication in STI processes”2013
- Author(s)
  四ノ宮成祥
- Organizer
  東京大学科学技術イノベーション政策のための科学第２回国際シンポジウム『科学技術イノベーションプロセスのためのエビデンスの利用と人材育成』
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] ラット自然発症食道腫瘍モデルにおける内因性蛍光に基づく病態イメージング2013
- Author(s)
  立石昇一朗、堀内俊克、谷口裕亮、梅津新矢、小倉俊一郎、四ノ宮成祥、守本祐司
- Organizer
  第3回ポルフィリン-ALA学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23659599
[Presentation] シンポジウム１　分子標的診断・治療の進歩と今後　痛風・高尿酸血症と尿酸トランスポーター2013
- Author(s)
  松尾洋孝、四ノ宮成祥
- Organizer
  第31回日本ヒト細胞学会学術集会
- Place of Presentation
  所沢
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] シンポジウムIII「癌の発生・進展とアポトーシス」肝癌発癌モデルを用いたHGF/SF-MET系の役割解析2012
- Author(s)
  四ノ宮成祥
- Organizer
  第30回日本ヒト細胞学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] セッション３バイオセキュリティ　合成生物学研究とバイオセキュリティ教育2012
- Author(s)
  四ノ宮成祥
- Organizer
  「細胞を創る」研究会5.0
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] 癌発育の多段階に関与する癌遺伝子Metを標的とした分子標的薬開発の試み2012
- Author(s)
  四ノ宮成祥
- Organizer
  日本婦人科がん分子標的研究会第11回学術集会
- Place of Presentation
  日光（栃木）
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] シンポジウムIII　「癌の発生・進展とアポトーシス」　肝癌発癌モデルを用いたHGF/SF-MET系の役割解析2012
- Author(s)
  四ノ宮成祥
- Organizer
  第30回日本ヒト細胞学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] 痛風病因遺伝子ABCG2の変異と血清尿酸値との関連2012
- Author(s)
  中山昌喜, 松尾洋孝, 及川雄二, 高田雄三, 中島宏, 中村好宏, 井上寛規, 森厚嘉, 内藤真理子, 菱田朝陽, 若井建志, 丹羽和紀, 横井裕, 浜島信之, 四ノ宮成祥
- Organizer
  第22回日本疫学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] 「生命科学のデュアルユース問題とバイオセキュリティ教育」　（日本分子生物学会フォーラム１F11　分子生物学とバイオセキュリティ：「研究者コミュニティと資金配分機関に求められる役割と責任」）2012
- Author(s)
  四ノ宮成祥
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] 癌発育の多段階に関与する癌遺伝子 Met を標的とした分子標的薬開発の試み2012
- Author(s)
  四ノ宮成祥, 吉森篤史, 高橋哲, 中山昌喜, 松尾洋孝, 守本祐司, 佐伯和徳, 高澤涼子, 田沼靖一
- Organizer
  日本婦人科がん分子標的研究会第11回学術集会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] Panel II: Risks and Concerns Associated with HPAI H5N1 GOF Research, Panel VI: Overview and Discussion of Main Points2012
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  An International Consultative Workshop Gain-of-Function (GOF) Research on Highly Pathogenic Avian Influenza (HPAI) H5N1 Viruses
- Place of Presentation
  Bethesda, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] Met チロシンキナーゼを標的とした低分子抗腫瘍薬開発の試み2011
- Author(s)
  四ノ宮成祥, 吉森篤史, 高橋哲, 中山昌喜, 松尾洋孝, 守本祐司, 佐伯和徳, 高澤涼子, 田沼靖一
- Organizer
  第29回日本ヒト細胞学会学術集会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] マウスMRSA膝関節炎に対する予防的光線力学療法(preventive PDT)の感染抑制効果2011
- Author(s)
  田中優砂光、Michael R.Hamblin、Pawel Mroz、Tianhong Dai、Liyi Huang、木下学、吉原愛雄、関修司、四ノ宮成祥、根本孝一、守本祐司
- Organizer
  第21回日本光線力学学会学術講演会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] 細胞培養系を用いた一酸化炭素中毒神経障害メカニズム解析の試み2011
- Author(s)
  四ノ宮成祥, 中山昌喜, 松尾洋孝, 守本祐司, 藤田真敬, 立花正一, 鈴木信哉
- Organizer
  第8回日本臨床高気圧酸素・潜水医学会
- Place of Presentation
  東京
- Year and Date
  2011-08-05
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] 痛風リスク遺伝子の迅速SNPタイピング2011
- Author(s)
  高田雄三、松尾洋孝、四ノ宮成祥、川口克彦、丹羽和紀
- Organizer
  第60回日本医学検査学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] Metチロシンキナーゼを標的とした低分子抗腫瘍薬開発の試み2011
- Author(s)
  四ノ宮成祥, 吉森篤史, 高橋哲, 中山昌喜, 松尾洋孝, 守本祐司, 佐伯和徳, 高澤涼子, 田沼靖一
- Organizer
  第29回日本ヒト細胞学会学術集会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] How do we tackle emerging risks posed by recent development of bio-technology?-Sharing good practices from the experience of college education and activities in the academic community2011
- Author(s)
  Nariyoshi Shinomiya
- Organizer
  7^<th> Review Conference, side event "Dual-use issues and the role of life scientists"
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] ラット正所性食道がんモデルを用いた細径内視鏡下での光線力学的診断2011
- Author(s)
  宮崎幸造, 守本祐司, 比留間瞳, 井上明季, 野本貴大, 福島重人, 岩屋啓一, 四ノ宮成祥, 西山伸宏, 片岡一則
- Organizer
  第32回日本レーザー医学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] 「進化する合成生物学と生命倫理」合成生物学の持つデュアルユース性と生命科学者教育2011
- Author(s)
  四ノ宮成祥
- Organizer
  第23回日本生命倫理学会年次大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] デンドリマーポルフィリンミセルのPDD・PDT効果の検証2011
- Author(s)
  比留間瞳, 守本祐司, 宮崎幸造, 井上明季, 野本貴大, 福島重人, 四ノ宮成祥, 西山伸宏, 片岡一則
- Organizer
  第32回日本レーザー医学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] 細菌感染症に対する光線力学的治療(PDT)のmodality : in vivoにおけるPDTの有効性発揮には好中球が必須である2011
- Author(s)
  田中優砂光, Michael R.Hamblin, Pawel Mroz, 木下学, 吉原愛雄, 関修司, 四ノ宮成祥, 根本孝一, 守本祐司
- Organizer
  第32回日本レーザー医学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] Development of Small Molecule Inhibitors for Met, a Receptor Tyrosine Kinase2011
- Author(s)
  Nariyoshi Shinomiya, Atsushi Yoshimori, Seiichi Tanuma
- Organizer
  BIT's 9th Annual Congress of 2011 International Drug Discovery Science and Technology
- Place of Presentation
  Shenzhen, China
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] ヒト肺癌細胞に対する光増感剤内包ミセルの細胞傷害性の検証2011
- Author(s)
  宮崎幸造、守本祐司、熊谷康顕、福島重人、比留間瞳、四ノ宮成祥、西山伸宏、片岡一則
- Organizer
  第29回日本ヒト細胞学会学術集会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] 近年の生物兵器の動向と生物兵器禁止条約2011
- Author(s)
  四ノ宮成祥
- Organizer
  第17回安全保障輸出管理責任者講演会
- Place of Presentation
  東京
- Year and Date
  2011-05-23
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] 光の音響的・機械的作用を用いた光感受性薬剤のドシメトリーとデリバリー(シンポジウム)2011
- Author(s)
  佐藤俊一、角井泰之、長谷川博之、四ノ宮成祥、齋藤大蔵、寺川光洋
- Organizer
  第21回日本光線力学学会学術講演会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] Development of Small Molecule Inhibitors for Met, a Receptor Tyrosine Kinase2011
- Author(s)
  Shinomiya N., Yoshimori A., and Tanuma S.
- Organizer
  BIT's 9th Annual Congress of 2011 International Drug Discovery Science and Technology
- Place of Presentation
  Shenzhen Convention & Exhibition Center, China.
- Data Source
  KAKENHI-PROJECT-23300365
[Presentation] Interleukin-18 therapy enhances Kupffer cell-mediated bacterial elimination in post-burn infection models via the activation of NK cell function2010
- Author(s)
  Kinoshita M, Shinomiya N, Miyazaki H, Ono S, Saitoh D, Seki S
- Organizer
  Chemical and Biological Defense Science and Technology (CBD S&T) 2010
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-22592027
[Presentation] CpG-oligodeoxynucleotides challenge induces severe multi-organ damage and lethality via TNF and FasL-mediated NKT cell activation in aged mice2010
- Author(s)
  Kinoshita M, Shinomiya N, Kawabata T, Seki S
- Organizer
  Chemical and Biological Defense Science and Technology (CBD S&T) 2010
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-22592027
[Presentation] デュアルユース問題のこれまでの流れ
- Author(s)
  四ノ宮成祥
- Organizer
  日本学術会議公開シンポジウム　「デュアルユース問題とBSL4施設シンポジウム」
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23300365
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SHINOMIYA Nariyoshi 四ノ宮 成祥

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Development of diagnostic technique through a new, high-sensitivity gene-expression analysis: to promote secondary prevention against cancers which are difficult to detect earlyPrincipal Investigator

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Development of new small molecules for Met stimulator and building up foundations of medical applicationPrincipal Investigator

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Genetic and epidemiological analysis of noise-induced hearing loss (NIHL) towards its tailor-made medicine and preventionPrincipal Investigator

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Development of new dual inhibitors for c-Met targeting both allosteric and catalytic sitesPrincipal Investigator

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Development and biological evaluation of small molecule inhibitors for Met using a new strategyPrincipal Investigator

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Development of MR imaging technology and cell labeling contrast agents for tracking the biokinetics of dendritic cells.Principal Investigator

SHINOMIYA Nariyoshi 四ノ宮成祥

[Book] すぐに分かるＣＢＲＮ　事態対処Ｑ＆Ａ―いざという時に役立つ！2020

[Book] いざという時に役立つ！すぐに分かるCBRN事態対処Q&A2020