ono satoshi 小野聡

… Alternative Names

ONO Satoshi 小野聡

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Researcher Number	30531355
Affiliation (Current)	2025: 東京医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 東京医科大学, 医学部, 兼任教授 2014 – 2017: 東京医科大学, 医学部, 教授 2015: 東京医科大学, 八王子医療センター特定集中治療部, 教授 2014: 東京医科大学, 防衛医学研究センター, 教授 2010 – 2013: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 防衛医学研究センター, 准教授 2011 – 2012: 防衛医科大学校, 防衛医学研究センター, 准教授
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55060:Emergency medicine-related / Emergency medicine Except Principal Investigator Emergency medicine / Basic Section 55060:Emergency medicine-related / Laboratory medicine / Medical and hospital managemen / Digestive surgery / Integrated Nutrition Science / General surgery / Bacteriology (including Mycology)
Keywords	Principal Investigator 免疫麻痺 / 敗血症 / IFN-γ / 制御性T細胞 / 外科侵襲 / エンドトキシン / エンドトキシン吸着療法 / sepsis / NK細胞 / 周術期管理 … More / 免疫抑制細胞 / 好中球リンパ球比 / 骨髄由来免疫抑制細胞 / 免疫抑制 / 重症病態 / 長期予後 / 術後感染性合併症 / 免疫抑制細胞集団 / CD4+T cell / regulatory T cell / CD4陽性T cell / サイトカイン / 白血球分画 / PD-L1 / 単核球 / エンドトキシン吸着カラム / PD-1 / CD4T細胞 / 免疫不全 / compromised host / ポリミキシンB / 小動物用カラム / 動物敗血症モデル / 敗血症性免疫不全 / 血液浄化療法 / IL-18受容体 / Interleukin-18 / TGF-β / IL-10 / 肝転移 / 腫瘍免疫 / 感染 … More Except Principal Investigator 敗血症 / 光線力学療法 / 活性酸素 / クッパー細胞 / MPLAプレコンディショニン / MPLAプレコンディショニング / compromised host / 殺菌作用 / マクロファージ / 貪食活性 / 合成CRP / 重症感染症 / ナノシート / レスベラトロール / compromised hosts / Helicobacter pylori / 好中球 / 熱傷 / MLPAプレコンディショニング / 薬剤感受性迅速診断 / 細菌活性測定チップ / コラーゲン / 繊維化 / COVID-19 / Fibrosis / Collagen / ARDS / 生態防御 / 生体防御 / 品質管理 / 重症病態 / エネルギー代謝 / マイトファジー / ミトコンドリアダイナミクス / 外傷 / 重症熱傷 / 品質管理機構 / ミトコンドリア / Compromised hosts / 抗菌活性評価チップ / 薬剤耐性菌敗血症 / Compromised hostｓ / 抗菌活性測定チップ / 貪食細胞機能強化 / LPSプレコンディショニング / 薬剤耐性菌血症 / 自然免疫 / 殺菌活性 / 腎障害 / 感染症 / C5aR / C5a / MBL / C4d / C5b-9 / C5 / 抗体親和性 / ANCA関連腎炎 / 免疫複合体 / レクチン経路 / 副経路 / 古典経路 / 補体 / リスクマネジメント / 渦電流 / 銀繊維 / 遺残ガーゼ / H.pylori除菌 / H.pylori感染症 / H.pylori / 除菌療法 / Photo dynamic therapy / 好中球機能 / 食細胞 / 貪食 / 侵襲 / 脂肪滴 / ADFP / 脂肪肝 / 上皮化 / 同種皮膚 / 抗菌能 / 抗菌性 / 機能性ナノシート / 創傷治癒 / 血管新生 / 創傷被覆材 / 感染制御 / マイクロスキン / グルココルチコイド受容体 / 核内受容体 / ナノ医学 / エンドトキシントレランス / 止血ナノ粒子 / ursodepxycolic acid / 外科侵襲 / 国際情報交換 / 見張りリンパ節 / ICG / ナノ粒子 / センチネルリンパ節 / 腹膜播種 / 胃癌 / MKN45 / cell proliferation / Proteus mirabillis / 胃がん細胞 / 胃内起因菌 / 病原性 / NK細胞 / 細菌感染 / マウス熱傷モデル / 免疫不全 / CD11b陽性Kupffer細胞 / CD68陽性Kupffer細胞 / CD11b陽性クッパー細胞 / CD68陽性クッパー細胞 / IL-18 / 熱傷後感染 / 複合免疫不全 Less

Analysis of the bifurcation between COVID-19 and conventional ARDS from the viewpoint of collagen regulation.
- Principal Investigator
  
  蒲原英伸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Tokyo Medical University
重症病態での免疫抑制細胞集団の解析とその制御Principal Investigator
- Principal Investigator
  
  小野聡
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Tokyo Medical University
Multidimensional therapeutic strategy against severe infection/sepsis, focusing on respiratory activity of bacteria and activation of host phagocytic cells
- Principal Investigator
  
  Kinoshita Manabu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  National Defense Medical College
Mitochondrial function and quality control in critical illness
- Principal Investigator
  
  Miyazaki Hiromi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  National Defense Medical College
Novel therapeutic strategy against drug-resistant bacterial sepsis in compromised hosts focusing on enhancing bactericidal activity of macrophages
- Principal Investigator
  
  Kinoshita Manabu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  National Defense Medical College
Elucidation for the mechanism of kidney injury and the biomarker related with complement activation in infection associated kidney diseases
- Principal Investigator
  
  Oda Takashi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical University
Pathophysiological analysis of immunodeficiency in critical illnessPrincipal Investigator
- Principal Investigator
  
  ONO SATOSHI
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Medical University
The therapeutic strategy for burn-induced immunosuppression: PPARgamma activation for control of innate immune response
- Principal Investigator
  
  MIYAZAKI HIROMI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  National Defense Medical College
Development of Retained Surgical Gauze Detection System before Closing Surgical Incisions.
- Principal Investigator
  
  Hinoki Akinari
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical and hospital managemen
- Research Institution
  Nagoya University
The therapeutic strategy for burn-induced immunosuppression: Regulation of phagocytes function.
- Principal Investigator
  
  MIYAZAKI Hiromi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  National Defense Medical College
Photo dynamic therapy for eradication of Helicobacter pylori
- Principal Investigator
  
  Hiraki Shuichi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  National Defense Medical College
Blood purification for sepsis-induced immunoparalysisPrincipal Investigator
- Principal Investigator
  
  ONO SATOSHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Tokyo Medical University
Management against surgical stress in compromised hosts
- Principal Investigator
  
  Kinoshita Manabu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Emergency medicine
- Research Institution
  National Defense Medical College
A novel therapeutic approach to severe burns by microskin grafts combined with ultra-thin nanosheets
- Principal Investigator
  
  SAITOH Diazoh
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  National Defense Medical College
Resveratrol ameliorates high-fat-diet-induced fatty liver by increasing CD68 positive Kupffer cells.
- Principal Investigator
  
  Nishikawa Kahoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Chuo University
  National Defense Medical College
Photodynamic therapy using nanoparticle loaded with indocyanine green for experimental metastasis model of gastric cancer
- Principal Investigator
  
  TSUJIMOTO Hironori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Defense Medical College
Surgical stress induces immunosuppression and this condition contributes to tumor growthPrincipal Investigator
- Principal Investigator
  
  ONO Satoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Defense Medical College
Bacterial pathogen Helicobacter pylori may augment gene expressions of TLR4 and TLR5 on cancer cells under coexistence with another gastric bacteria Proteus mirabilis
- Principal Investigator
  
  NISHIKAWA Kahoko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  防衛医科大学校
   National Defense Medical College
Mechanical analyses and treatment of immunodeficiency following burn injury
- Principal Investigator
  
  KINOSHITA Manabu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  National Defense Medical College

[Book] 術後ケアとドレーン管理のすべて　編集：竹末芳生、藤野智子2016
- Author(s)
  小野　聡、池田寿昭
- Total Pages
  402
- Publisher
  照林社
- Data Source
  KAKENHI-PROJECT-26670795
[Book] エンドトキシン・自然免疫研究192016
- Author(s)
  小野　聡、木下　学、池田寿昭
- Total Pages
  60
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-26670795
[Book] 敗血症（セプシス）救命治療の最前線　竹末芳生編　セプシス治療薬　セプシス治療薬の日本での活用2014
- Author(s)
  小野　聡
- Total Pages
  397
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-26670795
[Book] 敗血症（セプシス）　救命治療の最前線　セプシス治療薬の日本での活用2014
- Author(s)
  小野　聡
- Total Pages
  399
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-23591886
[Book] 周術期感染管理テキスト　重症敗血症、敗血症性ショック2012
- Author(s)
  小野　聡
- Total Pages
  230
- Publisher
  編集：日本外科感染症学会、（株）診断と治療社、東京
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Population Pharmacokinetic Modeling of Unbound Meropenem in Patients Undergoing Continuous Renal Replacement Therapy: An Observational Cohort Study.2024
- Author(s)
  Oda Kazutaka, Jono Hirofumi, Kamohara Hidenobu, Saito Hideyuki
- Journal Title
  
  Therapeutic Drug Monitoring
  
  Volume: In press Issue: 5 Pages: 68-78
- DOI
  10.1097/ftd.0000000000001222
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09173, KAKENHI-PROJECT-18K08893
[Journal Article] 特集：ICUで遭遇する免疫異常　正常な免疫機能-自然免疫、獲得免疫の基本的な役割と機能-2023
- Author(s)
  小野　聡
- Journal Title
  
  INTENSIVIST
  
  Volume: 15 Pages: 553-560
- Data Source
  KAKENHI-PROJECT-21K09056
[Journal Article] 特集：新・外科感染症診療ハンドブック　周術期敗血症とDICに対する治療戦略2022
- Author(s)
  秋元寿文、小野　聡
- Journal Title
  
  臨床外科
  
  Volume: 77 Pages: 1425-29
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] 特集：新・外科感染症診療ハンドブック　周術期敗血症とDICに対する治療戦略2022
- Author(s)
  秋元寿文、小野　聡
- Journal Title
  
  臨床外科
  
  Volume: 77 Pages: 1425-29
- Data Source
  KAKENHI-PROJECT-21K09056
[Journal Article] A case report of PR-3-ANCA-positive glomerulonephritis with histological features of GPA associated with infectious endocarditis2021
- Author(s)
  Hirata Momoko、Miyazawa Haruhisa、Morino Junki、Kaneko Shohei、Minato Saori、Katsunori Yanai、Ishii Hiroki、Kitano Taisuke、Ito Kiyonori、Hirai Keiji、Oda Takashi、Shimizu Akira、Ueda Yoshihiko、Morishita Yoshiyuki
- Journal Title
  
  Medicine
  
  Volume: 100 Issue: 32 Pages: e26905-e26905
- DOI
  10.1097/md.0000000000026905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08992, KAKENHI-PROJECT-21K08604
[Journal Article] 術後臓器不全におけるメディエータ制御2021
- Author(s)
  島内貴弘、小野　聡
- Journal Title
  
  外科と代謝・栄養
  
  Volume: 55 Pages: 22-28
- NAID
  130007998479
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] Potential mechanisms of tumor progression associated with postoperative infectious complications2021
- Author(s)
  Tsujimoto H, Kobayashi M, Sugasawa H, Ono S, Kishi Y, Ueno H.
- Journal Title
  
  Cancer and Metastasis Reviews
  
  Volume: 40 Pages: 285-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09056
[Journal Article] 術後臓器不全におけるメディエータ制御2021
- Author(s)
  島内貴弘、小野　聡
- Journal Title
  
  外科と代謝・栄養
  
  Volume: 55 Pages: 22-29
- NAID
  130007998479
- Data Source
  KAKENHI-PROJECT-21K09056
[Journal Article] Lipopolysaccharide Preconditioning Augments Phagocytosis of Malaria-Parasitized Red Blood Cells by Bone Marrow-Derived Macrophages in the Liver, Thereby Increasing the Murine Survival after Plasmodium yoelii Infection2021
- Author(s)
  Ono Takeshi、Yamaguchi Yoko、Nakashima Hiroyuki、Nakashima Masahiro、Ishikiriyama Takuya、Seki Shuhji、Kinoshita Manabu
- Journal Title
  
  Infection and Immunity
  
  Volume: 89 Issue: 11
- DOI
  10.1128/iai.00249-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07493, KAKENHI-PROJECT-20K07438, KAKENHI-PROJECT-21H03038
[Journal Article] Potential mechanisms of tumor progression associated with postoperative infectious complications2021
- Author(s)
  Tsujimoto H, Kobayashi M, Sugasawa H, Ono S, Kishi Y, Ueno H.
- Journal Title
  
  Cancer and Metastasis Reviews
  
  Volume: 40 Pages: 285-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] Individual Lymphocyte Sensitivity to Steroids as a Reliable Biomarker for Clinical Outcome after Steroid Withdrawal in Japanese Renal Transplantation2021
- Author(s)
  Okihara Masaaki、Takeuchi Hironori、Kikuchi Yukiko、Akashi Isao、Kihara Yu、Konno Osamu、Iwamoto Hitoshi、Oda Takashi、Tanaka Sachiko、Unezaki Sakae、Hirano Toshihiko
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 8 Pages: 1670-1670
- DOI
  10.3390/jcm10081670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08992, KAKENHI-PROJECT-21K08604
[Journal Article] A potential mechanism of tumor progression during systemic infections via the hepatocyte growth factor (HGF)/c-Met signaling pathway.2020
- Author(s)
  Tsujimoto H, Horiguchi H, Matsumoto Y, Takahata R, Shinomiya N, Yamori T, Miyazaki H, Ono S, Saitoh D, Kishi Y, Ueno H.
- Journal Title
  
  J Clin. Med
  
  Volume: 9 Issue: 7 Pages: 2074-2074
- DOI
  10.3390/jcm9072074
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10524, KAKENHI-PROJECT-18H02685
[Journal Article] Impact of perioperative high mobility group box chromosomal protein 1 expression onlong-term outcomes in patients with esophageal squamous cell carcinoma2020
- Author(s)
  Tsujimoto H, Horiguchi H, Takahata R, Ono S, Yaguchi Y, Nomura S, Ito N, Harada M, Nagata H, Ishibashi Y, Kouzu K, Tsuchiya S, Itazaki Y, Fujishima S, Kishi Y, Ueno H.
- Journal Title
  
  J Gastroenterological and Hepatology
  
  Volume: 35 Issue: 5 Pages: 788-794
- DOI
  10.1111/jgh.14854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] 癌患者における手術侵襲と炎症コントロール2020
- Author(s)
  小野　聡、青笹季文、岩本一亜、辻本広紀
- Journal Title
  
  消化器外科
  
  Volume: 43 Pages: 1267-75
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] Lipopolysaccharide preconditioning reduces liver metastasis of Colon26 cells by enhancing antitumor activity of natural killer cells and natural killer T cells in murine liver2020
- Author(s)
  Nishikawa Makoto、Kinoshita Manabu、Morimoto Yuji、Ishikiriyama Takuya、Nakashima Masahiro、Nakashima Hiroyuki、Ono Takeshi、Seki Shuhji、Moriya Tomoyuki、Yamamoto Junji、Kishi Yoji
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: Online Issue: 7 Pages: 1889-1898
- DOI
  10.1111/jgh.15375
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07438, KAKENHI-PROJECT-18H02907, KAKENHI-PROJECT-17K10682
[Journal Article] 特集：消化器・一般外科における感染対策・周術期管理　外科侵襲と生体反応-サイトカインを中心に2020
- Author(s)
  秋元寿文、小野　聡
- Journal Title
  
  手術
  
  Volume: 74 Pages: 1671-79
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] 術前検査　免疫学的評価2020
- Author(s)
  小野　聡、辻本広紀
- Journal Title
  
  消化器外科　術前・術後管理必携
  
  Volume: 43 Pages: 590-94
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] すぐに使える周術期管理マニュアル　V.特殊な治療手技　血液浄化療法・PMX-DHP2019
- Author(s)
  小野　聡、青笹季文、蒲池良平、岡崎幸生
- Journal Title
  
  臨床外科74
  
  Volume: 74 Pages: 344-48
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] 特集：救急治療領域の炎症と凝固障害　プロカルシトニン2019
- Author(s)
  小野　聡
- Journal Title
  
  炎症と免疫
  
  Volume: 27 Pages: 144-146
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] 腹部救急疾患と敗血症2019
- Author(s)
  小野　聡
- Journal Title
  
  久喜市医師会報
  
  Volume: 22 Pages: 2-6
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] 敗血症診療ガイドラインとARDS2018
- Author(s)
  須田慎吾、小野　聡、奈倉武郎、池田寿昭
- Journal Title
  
  呼吸器内科
  
  Volume: 33 Pages: 84-89
- NAID
  40021450803
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] Mechanisms of sepsis-induced immunosuppression and immunological modification therapies for sepsis2018
- Author(s)
  Satoshi Ono, Hironori Aosasa, Shuichi Hiraki, Suefumi Aosasa
- Journal Title
  
  Ann Gastroenterol Surg
  
  Volume: 2 Pages: 351-358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] DICのすべて　ISTH DIC診断基準2018
- Author(s)
  池田寿昭、小野　聡、須田慎吾
- Journal Title
  
  救急・集中治療
  
  Volume: 30 Pages: 188-191
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] Impact of angiotesin-converting enzyme 2 levels on postoperative pneumonia after esophagectomy2018
- Author(s)
  Nomura S, Tsujimoto H, Aosasa S, Saitoh D, Has K, Ono S, Yamamoto J, Ueno H
- Journal Title
  
  J Surg Res
  
  Volume: 224 Pages: 200-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] 特集：エキスパートに学ぶ輸液管理のすべて　重症患者に対する輸血療法のタイミング2017
- Author(s)
  小野　聡、池田　寿昭
- Journal Title
  
  救急・集中治療
  
  Volume: 29 Pages: 932-937
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] Randomized clinical trial of 24 versus 72 h antimicrobial prophylaxis in patients undergoing open total gastrectomy for gastric cancer2017
- Author(s)
  Takagane A, Mohri Y, Konishi T, Fukushima R, Noie T, Sueyoshi S, Omura K, Ono S, Kusunoki M, Mochizuki H, Sumiyama Y
- Journal Title
  
  Brit J Surgery
  
  Volume: 104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10524
[Journal Article] ショック患者における輸液療法の実際2016
- Author(s)
  小野　聡、須田慎吾、奈倉武郎、池田寿昭
- Journal Title
  
  救急医学
  
  Volume: 40 Pages: 1633-1640
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] Perioperative chemoradiation therapy for esophageal cancer is a risk factor for the elevation of high mobilitygroup box-1, leading to an increase in postoerative severe pulmonary complications2016
- Author(s)
  Takahata R, Ono S, Tsujimoto H, Hiraki S, Aosasa S, Yamamoto J, Hase K
- Journal Title
  
  Dis Esophagus
  
  Volume: 29 Pages: 70-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] 周術期生体反応の特性と感染性合併症対策2016
- Author(s)
  小野　聡
- Journal Title
  
  東京医科大学雑誌
  
  Volume: 74 Pages: 123-135
- NAID
  120005845840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] 外科侵襲時の免疫不全の病態と癌手術患者の長期予後2016
- Author(s)
  小野　聡、辻本広紀
- Journal Title
  
  外科と代謝栄養
  
  Volume: 50 Pages: 265-277
- NAID
  130005308707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] Perioperative programmed death-1 expression on CD4+ T cells predicts the incidence of postoperative infectious complications2015
- Author(s)
  Kubo T, Ono S, Miyazaki H, Saitoh D, Yamamoto J, Hase K.
- Journal Title
  
  Shock
  
  Volume: 44 Pages: 323-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] Burn-Evoked Reactive Oxygen Species Immediately After Injury are Crucial to Restore the Neutrophil Function Against Postburn Infection in Mice2015
- Author(s)
  Miyazaki H, Kinoshita M, Ono S, Seki S, Saitoh D
- Journal Title
  
  Shock
  
  Volume: 44 Issue: 3 Pages: 252-257
- DOI
  10.1097/shk.0000000000000404
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462773, KAKENHI-PROJECT-25293369
[Journal Article] Theranostic photosensitive nanoparticles for lymph node metastatis of gastric cancer2015
- Author(s)
  Tsujimoto, H., Morimoto, Y., Takahata, R., Nomura, S., Yoshida, K., Hiraki, S., Horiguchi, H., Miyazaki, H., Ono, S., Saito, D., Hara, I., Ozeki, E., Yamamoto, J., Hase, K.
- Journal Title
  
  Annals of surgical oncology
  
  Volume: 22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] Burn-evoked reactive oxygen species immediately after injury are crucial to restore the neutrophil function against post-burn infection in mice2015
- Author(s)
  Miyazaki H, Kinoshita M, Ono S, Seki S, Saitoh D.
- Journal Title
  
  Shock
  
  Volume: 44 Pages: 252-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] CD47 is an adverse prognostic factor and a therapeutic target in gastric cancer.2015
- Author(s)
  Yoshida K, Tsujimoto H, Matsumura K, Kinoshita M, Takahata R, Matsumoto Y, Hiraki S, Ono S, Seki S, Yamamoto J, Hase K.
- Journal Title
  
  Cancer Medicine
  
  Volume: 4 Issue: 9 Pages: 1322-1333
- DOI
  10.1002/cam4.478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293369
[Journal Article] 重症感染症における免疫療法の意義2015
- Author(s)
  小野　聡、池田寿昭、須田慎吾、泉谷義人、上野琢哉
- Journal Title
  
  ICUとCCU
  
  Volume: 39 Pages: 423-429
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] Abdominal Infection Suppresses the Number and Activity of Intrahepatic Natural Killer Cells and Promotes Tumor Growth in a Murine Liver Metastasis Model.2015
- Author(s)
  Matsumoto Y, Tsujimoto H, Ono S, Shinomiya N, Miyazaki H, Hiraki S, Takahata R, Yoshida K, Saitoh D, Yamori T, Yamamoto J, Hase K.
- Journal Title
  
  Annals of surgical oncology
  
  Volume: 23 Pages: 257-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] Resveratrol increases CD68+ Kupffer cells colocalized with adipose differentiation-related protein and ameliorates high-fat-diet-induced fatty liver in mice.2015
- Author(s)
  Nishikawa K, Iwaya K, Kinoshita M, Fujiwara Y, Akao M, Sonoda M, Thiruppathi S, Suzuki T, Hiroi S, Seki S, Sakamoto T.
- Journal Title
  
  Mol Nutr Food Res
  
  Volume: 12 Issue: 6 Pages: 564-564
- DOI
  10.1002/mnfr.201400564
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590457, KAKENHI-PROJECT-25504021, KAKENHI-PROJECT-25460508, KAKENHI-PROJECT-25293369
[Journal Article] Impact of the perioperative neutrophil-to-lymphocyte ratio on the long-term survival following an elective resection of colorectal carcinoma2014
- Author(s)
  Kubo T, Ono S, Ueno H, Shinto E, Yamamoto J, Hase K
- Journal Title
  
  Int J Colorectal Dis
  
  Volume: 29 Pages: 1091-1099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] Perioperative chemoradiation therapy for esophageal cancer is a risk factor for the elevation of high mobilitygroup box-1, leading to an increase in postoerative severe pulmonary complications2014
- Author(s)
  Takahata R, Ono S, Tsujimoto H, Hiraki S, Aosasa S, Yamamoto J, Hase K
- Journal Title
  
  Dis Esophagus
  
  Volume: - Issue: 1 Pages: 70-78
- DOI
  10.1111/dote.12261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] 急性血液浄化法　IV. 急性血液浄化法の適応疾患　重症壊死性筋膜炎に対する血液浄化2014
- Author(s)
  池田寿昭、小野　聡、上野琢哉
- Journal Title
  
  救急・集中治療
  
  Volume: 26 Pages: 449-457
- Data Source
  KAKENHI-PROJECT-26670795
[Journal Article] Photodynamic therapy using nanoparticle loaded with indocyanine green for experimental peritoneal dissemination of gastric cancer2014
- Author(s)
  Hironori Tsujimoto
- Journal Title
  
  Cancer Science
  
  Volume: 105 Issue: 12 Pages: 1626-1630
- DOI
  10.1111/cas.12553
- NAID
  130005163794
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591892, KAKENHI-PROJECT-26293295
[Journal Article] Immunoenhancing therapy with interleukin-18 against bacterial infection in immunocompromised hosts after severe surgical stress2013
- Author(s)
  Kinoshita M, Miyazaki H, Ono S, Seki S
- Journal Title
  
  J. Leukocyte. Biol
  
  Volume: 93 Pages: 689-698
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Predictive value of pleural and serum interleukin-6 levels for pneumonia and hypo-oxygenations after esophagectomy2013
- Author(s)
  Tsujimoto H, Takahata R, Nomura S, Kumano I, Matsumoto Y, Yoshida K, Hiraki S, Aosasa S, Ono S,Yamamoto J, Hase K.
- Journal Title
  
  J Surg Res
  
  Volume: 182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] 外科侵襲によるimmunoparalysisとその制御2013
- Author(s)
  小野　聡、平木修一、辻本広紀、木下学、齋藤大蔵
- Journal Title
  
  侵襲と免疫
  
  Volume: 22 Pages: 7-18
- Data Source
  KAKENHI-PROJECT-25293369
[Journal Article] Effective control of massive venous bleeding by “multi-overlapping therapy” using polysaccharide nanosheets in rabbit inferior vena cava injury model.2013
- Author(s)
  Hagisawa K, Saito A, Kinoshita M, Fujie T, Otani N, Shono S, Park YK, Takeoka S
- Journal Title
  
  J. Vasc. Surg: Venous and Lymphatic Disorders.
  
  Volume: 1 Issue: 3 Pages: 289-297
- DOI
  10.1016/j.jvsv.2013.04.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293369
[Journal Article] Removal of increased circulating CD4+CD25+Foxp3+ regulatory T cells in patients with septic shock using hemoperfusion with polymyxin B-immobilized fibers.2013
- Author(s)
  Ono, S
- Journal Title
  
  Surgery
  
  Volume: 153 Issue: 2 Pages: 262-271
- DOI
  10.1016/j.surg.2012.06.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592027, KAKENHI-PROJECT-25293369
[Journal Article] 特集：免疫不全と重症感染症-その病態と対策-　大侵襲手術周術期患者におけるimmunoparalysisと重症感染症2013
- Author(s)
  小野　聡、平木修一、高畑りさ、木村暁史、辻本広紀、齋藤大蔵
- Journal Title
  
  ICUとCCU
  
  Volume: 37 Pages: 593-602
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Immunoenhancing therapy with interleukin-18 against bacterial infection in immunocompromised hosts after severe surgical stress.2013
- Author(s)
  Kinoshita M, Miyazaki H, Ono S, Seki S
- Journal Title
  
  J. Leukocyte. Biol.
  
  Volume: 93 Issue: 5 Pages: 689-698
- DOI
  10.1189/jlb.1012502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293369
[Journal Article] Glucocorticoid receptor-dependent immunomodulatory effect of ursodeoxycholic acid on liver lymphocytes in mice.2013
- Author(s)
  Takigawa T, Miyazaki H, Kinoshita M, Kawarabayashi N, Nishiyama K, Hatsuse K, Ono S, Saitoh D, Seki S, Yamamoto J
- Journal Title
  
  Am J Physiol-Gastr L
  
  Volume: 305 Issue: 6 Pages: G427-G438
- DOI
  10.1152/ajpgi.00205.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293369
[Journal Article] Activation of CD11b+ Kupffer cells/macrophages as a common cause for exacerbation of TNF/ Fas-ligand-dependent hepatitis in hypercholesterolemic mice.2013
- Author(s)
  Nakashima, H
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 1 Pages: e49339-e49339
- DOI
  10.1371/journal.pone.0049339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592027, KAKENHI-PROJECT-25293369
[Journal Article] The effect of synthetic C-reactive protein on the in vitro immune response of human PBMCs stimulated with bacterial reagents.2013
- Author(s)
  Sato A, Nakashima H, Kinoshita M, Nakashima M, Ogawa Y, Shono S, Ikarashi M, Seki S
- Journal Title
  
  Inflammation
  
  Volume: 36 Issue: 4 Pages: 781-792
- DOI
  10.1007/s10753-013-9604-4
- NAID
  130004638709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293369
[Journal Article] Activation of CD11b+ Kupffer cells/macrophages as a common cause for exacerbation of TNF/ Fas-ligand-dependent hepatitis in hypercholesterolemic mice2013
- Author(s)
  Nakashima H, Ogawa Y, Shono S, Kinoshita M, Nakashima M, Sato A, Ikarashi M, Seki S
- Journal Title
  
  PLoS ONE
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Removal of increased circulating CD4+CD25+Foxp3+ regulatory T cells in patients with septic shock using hemoperfusion with polymyxin B-immobilized fibers2013
- Author(s)
  Ono S, Kimura A, Hiraki S, Takahata R, Tsujimoto H, Kinoshita M, Miyazaki H, Yamamoto J, Hase K, Saitoh D
- Journal Title
  
  Surgery
  
  Volume: 153 Pages: 262-271
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Immunoenhancing therapy with interleukin-18 against bacterial infection in immunocompromised hosts after severe surgical stress2013
- Author(s)
  Kinoshita M, Miyazaki H, Ono S, Seki S
- Journal Title
  
  J Leukoc Biol
  
  Volume: 93 Pages: 689-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Glucocorticoid receptor-dependent immunomodulatory effect of ursodeoxycholic acid on liver lymphocytes in mice2013
- Author(s)
  Takigawa T, Miyazaki H, Kinoshita M, Kawarabayashi N, Nishiyama K, Hatsuse K, Ono S, Saitoh D, Seki S, Yamamoto J
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Elevated preoperative C-reactive protein levels are a risk factor for the development of postoperative infectious complications following elective colorectal surgery2013
- Author(s)
  Kubo T, Ono S, Ueno H, Shinto E, Yamamoto J, Hase K
- Journal Title
  
  Langenbeck's Arch Surg
  
  Volume: 398 Pages: 965-971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Removal of increased circulating CD4+CD25+Foxp3+ regulatory T cells in patients with septic shock using hemoperfusion with polymyxin B-immobilized fibers2013
- Author(s)
  Ono S, Tsujimoto H, Kinoshita M, Miyazaki H, Hase K, Saitoh D, et al.
- Journal Title
  
  Surgery
  
  Volume: 153 Pages: 262-271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Neutralization of interleukin-10 or tumor growing factor-beta decreases the percentages of CD4+CD25+Foxp3+ regulatory T cells in septic mice, thus leading to an improved survival2012
- Author(s)
  Hiraki S, Ono S, Tsujimoto H, Kinoshita M, Takahata, R., Miyazaki H., Saitoh D, Hase K
- Journal Title
  
  Surgery
  
  Volume: 151 Pages: 313-22
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Systemic inflammatory response syndrome as a predictor of anastomotic leakage after esophagectomy2012
- Author(s)
  Tsujimoto H, Ono S, Hase K, et al.
- Journal Title
  
  Surgery Today
  
  Volume: 42 Pages: 141-146
- NAID
  10030230723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Fibrinogen γ-chain peptide-coated, adenosine diphosphate-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage2012
- Author(s)
  Nishikawa K, Hagisawa K, Kinoshita M, Shono S, Katsuno S, Doi M, Yanagawa R, Suzuki H, Iwaya K, Saitoh D, Sakamoto T, Seki S, Takeoka S, Handa M
- Journal Title
  
  J Thromb Haemost
  
  Volume: 10 Pages: 2137-2148
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Neutralization of interleukin-10 or transforming growth factor-βdecreases the percentages of CD4+CD25+Foxp3+ regulatory T cells in septic mice, thereby leading to an improved survival2012
- Author(s)
  Hiraki S, Ono S, Tsujimoto H, Kinoshita M, Miyazaki H, Saitoh D, Hase K
- Journal Title
  
  Surgery
  
  Volume: 151 Pages: 313-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] The postoperative serum interleukin-15 concentration correlates with organ dysfunction and the prognosis of septic patients following emergency gastrointestinal surgery2012
- Author(s)
  Kimura A, Ono S, Hiraki S, Takahata R, Tsujimoto H, Miyazaki H, Kinoshita M, Hatsuse K, Saitoh D, Hase K, Yamamoto J
- Journal Title
  
  J Surg Res
  
  Volume: 175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Neutralization of IL-10 restores the down-regulation of IL-18 receptor on NK cells and IFN-γ production in septic mice, thus leading to an improved survival2012
- Author(s)
  Hiraki S, Ono S, Kinoshita M, Tsujimoto H, Takahata, R., Miyazaki H., Saitoh D, Seki S, Hase K
- Journal Title
  
  SHOCK
  
  Volume: 37 Pages: 177-82
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] The postoperative serum interleukin-15 concentration correlates with organ dysfunction and the prognosis of septic patients following emergency gastrointestinal surgery2012
- Author(s)
  Kimura A, Ono S, Hiraki S, Takahata R, Tsujimoto H, Miyazaki H, Kinoshita M, Hatsuse K, Saitoh D, Hase K, Yamamoto J
- Journal Title
  
  J Surg Res
  
  Volume: 175
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] The postoperative serum interleukin-15 concentration correlates with organ dysfunction and the prognosis of septic patients following emergency gastrointestinal surgery2012
- Author(s)
  Kimura A, Ono S, Tsujimoto H, Miyazaki H, Kinoshita M, Saitoh D, Hase K. et al.
- Journal Title
  
  J Surg Res
  
  Volume: 175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Video-assisted thoracoscopic surgery for esophageal cancer attenuates postoperative systemic responses and pulmonary complications2012
- Author(s)
  Tsujimoto H, Takahata R, Nomura S, Yaguchi Y, Kumano I, Matsumoto Y, Yoshida K, Horiguchi H, Hiraki S, Ono S,Yamamoto J, Hase K.
- Journal Title
  
  Surgery
  
  Volume: 151 Pages: 667-673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Neutralization of IL-10 restores the down-regulation of IL-18 receptor on NK cells and IFN-γproduction in septic mice, thus leading to an improved survival2012
- Author(s)
  Hiraki S, Ono S, Kinoshita M, Tsujimoto H, Miyazaki H, Saitoh D, Hase K
- Journal Title
  
  Shock
  
  Volume: 37 Pages: 177-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Liposome-encapsulated hemoglobin attenuates cardiac dysfunction and sympathetic activity during hypohemoglobinemic shock2012
- Author(s)
  Nogami, Y., Takase, B., Kinoshita, M., Shono, S., Kaneda, S., Tanaka, Y., Kishimoto, S., Hattori, H., Ishihara, M
- Journal Title
  
  SHOCK
  
  Volume: 38 Pages: 159-164
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Video-assisted thoracoscopic surgery for esophageal cancer attenuates postoperative systemic responses and pulmonary complications2012
- Author(s)
  Tsujimoto H, Ono S, Hase K, et al.
- Journal Title
  
  Surgery
  
  Volume: 151 Pages: 667-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] An ultra-thin poly(L-lactic acid) nanosheet as a burn-wound dressing for protection against bacterial infection2012
- Author(s)
  Miyazaki H, Kinoshita M, Saito A, Fujie T, Kabata K, Hara E, Ono S, Takeoka S, Saitoh D
- Journal Title
  
  Wound Repair Regen
  
  Volume: 20 Pages: 573-579
- NAID
  10031181844
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Neutralization of interleukin-10 or transforming growth factor-β decreases the percentages of CD4+CD25+Foxp3+ regulatory T cells in septic mice, thereby leading to an improved survival2012
- Author(s)
  Hiraki S, Ono S,Tsujimoto H, Kinoshita M, Takahata R, Miyazaki H, Saitoh D, Hase K
- Journal Title
  
  Surgery
  
  Volume: 151 Pages: 313-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Assessment of a Tissue-Engineered Gastric Wall Patch in a Rat Model2012
- Author(s)
  Maemura T, Kinoshita M, Shin M, Miyazaki H, Tsujimoto H, Ono S, Hase K, Saitoh D
- Journal Title
  
  Artif. Organs
  
  Volume: 36 Pages: 409-17
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Neutralization of IL-10 restores the down-regulation of IL-18 receptor on NK cells and IFN-γ production in septic mice, thus leading to an improved survivaｌ2012
- Author(s)
  Hiraki S, Ono S, Kinoshita M, Tsujimoto H, Takahata R, Miyazaki H, Saitoh D, Seki S, Hase K.
- Journal Title
  
  Shock
  
  Volume: 37 Pages: 177-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Postoperative serum concentrations of High Mortality Group Box chromosomal protein-1 correlates to the duration of SIRS and pulmonary dysfunction following gastrointestinal surgery2011
- Author(s)
  Takahata, R., Ono S, Tsujimoto H, Hiraki S, Kimura A, Kinoshita M, Miyazaki H., Saitoh D, Hase K
- Journal Title
  
  J. Surg. Res.
  
  Volume: 170
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Preoperative Toll-like receptor expression in monocytes is associated with host immunological responses following gastrointestinal surgery2011
- Author(s)
  Ono S, Tsujimoto H, Hiraki S, Kinoshita M, Hase K
- Journal Title
  
  World J. Surg
  
  Volume: 35 Pages: 365-371
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Preoperative Toll-like receptor expression in monocytes is associated with host immunological responses following gastrointesinal surgery2011
- Author(s)
  Ono, S.
- Journal Title
  
  World.J.Surg.
  
  Volume: 35 Pages: 365-371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] The immunologic outcome of enhanced function of mouse liver lymphocytes and Kupffer cells by high-fat-cholesterol diet2011
- Author(s)
  Shono S, Habu Y, Nakashima M, Sato A, Nakashima H, Miyazaki H, Kinoshita M, Tsumatori G, Shinomiya N, Seki S
- Journal Title
  
  SHOCK
  
  Volume: 36 Pages: 484-93
- NAID
  40019087222
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] The immunologic outcome of enhanced function of mouse liver lymphocytes and Kupffer cells by high-fat-cholesterol diet2011
- Author(s)
  Shono, S.
- Journal Title
  
  SHOCK
  
  Volume: 35 Pages: 45-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Intraosseous transfusion with liposome-encapsulated hemoglobin improves mouse survival after hypohemoglobinemic shock without scavenging nitric oxide2011
- Author(s)
  Shono, S., Kinoshita, M., Takase, B., Nogami, Y., Kaneda, S., Ishihara, M., Saitoh, D., Kikuchi, M. and Seki, S
- Journal Title
  
  SHOCK
  
  Volume: 35 Pages: 45-52
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Augmented bacterial elimination by Kupffer cells after IL-18 pretreatment via IFN-g produced from NK cells in burn-injured mice.2011
- Author(s)
  Miyazaki, H., Kinoshita M., Ono S., Nakashima M., Hara E., Ohno H., Seki S., and Saitoh D
- Journal Title
  
  Burns
  
  Volume: 37 Pages: 1208-1215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Enhancement of neutrophil function by IL-18 therapy protects burn-injured mice from MRSA infection.2011
- Author(s)
  Kinoshita M, Miyazaki H., Ono S, Inatsu, A., Nakashima, H., Tsujimoto, H., Shinomiya, N., Saitoh, D., Seki, S
- Journal Title
  
  Infect Immun
  
  Volume: 79 Pages: 2670-80
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Postoperative serum concentrations of high mobility group box chromosomal protein-1 correlates to the duration of SIRS and pulmonary dysfunction following gastrointestinal surgery2011
- Author(s)
  Takahata R, Ono S, Tsujimoto H, Hiraki S, Kimura A, Kinoshita M, Miyazaki H, Saitoh D, Hase K.
- Journal Title
  
  J Surg Res
  
  Volume: 170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] One-step nucleic acid amplication (OSNA) for the application of sentinel node concept in gastric cancer2011
- Author(s)
  Yaguchi Y,Sugasawa H, Tsujimoto H, Takata H, Nakabayashi K, Ichikura T, Ono S, Hiraki S, Sakamoto N, Horio T, Kumano I, Otomo Y, Mochizuki H, Yamamoto J, Hase K.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 18 Pages: 2289-2296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Preoperative toll-like receptor expression in monocytes is associated with host immunological responses following gastrointestinal surgery.2011
- Author(s)
  Ono S, Tsujimoto H, Hiraki S, Kinoshita M, Hase K.
- Journal Title
  
  World J Surg
  
  Volume: 35 Pages: 365-371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Augmented bacterial elimination by Kupffer cells after IL-18 pretreatment via IFN-gamma produced from NK cells in burn-injured mice2011
- Author(s)
  Miyazaki H., Kinoshita M, Ono S, Nakashima M, Hara E, Ohno H, Seki S, Saitoh D
- Journal Title
  
  BURNS
  
  Volume: 37 Pages: 1208-1215
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Enhancement of neutrophil function by interleukin-18 therapy protects burn-injured mice from methicillin-resistant staphylococcus aureus2011
- Author(s)
  Kinoshita M, Miyazaki H, Ono S, Inatsu A, Nakashima H, Tsujimoto H, Shinomiya N, Saitoh D, Seki S.
- Journal Title
  
  Infection and Immunity
  
  Volume: 79 Pages: 2670-2680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Intraosseous transfusion with liposome-encapsulated hemoglobin improves mouse survival after hypohemoglobinemic shock without scavenging nitric oxide2011
- Author(s)
  Shono, S
- Journal Title
  
  SHOCK
  
  Volume: 36 Pages: 484-493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Preoperative toll-like receptor expression in monocytes is associated with host immunological responses following gastrointestinal surgery2011
- Author(s)
  Ono S, Tsujimoto H, Hiraki S, Kinoshita M, Hase K
- Journal Title
  
  World J Surg
  
  Volume: 35 Pages: 365-371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Enhancement of neutrophil function by interleukin-18 therapy protects burn-injured mice from methicillin-resistant staphylococcus aureus2011
- Author(s)
  Kinoshita M, Miyazaki H, Ono S, et al.
- Journal Title
  
  Infection and Immunity
  
  Volume: 79(7) Pages: 2670-2680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Postoperative serum concentrations of high mobility group box chromosomal protein-1 correlates to the duration of SIRS and pulmonary dysfunction following gastrointestinal surgery2011
- Author(s)
  Takahata R, Ono S, Tsujimoto H, Kinoshita M, Miyazaki H, Saitoh D, Hase K
- Journal Title
  
  J Surg Res
  
  Volume: 170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591886
[Journal Article] Characteristic changes in heart rate variability induces during hemorrhagic shock, and effect of liposome-encapsulated hemoglobin in rats2010
- Author(s)
  Nogami, Y., Takase, B., Kinoshita, M., Shono, S., Kaneda, S., Ishihara, M., Kikuchi, M., Maehara, T
- Journal Title
  
  J Arrhythmia
  
  Volume: 26 Pages: 189-198
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Sealing effect of a polysaccharide nanosheet for murine cecal puncture2010
- Author(s)
  Fujie, T., Kinoshita, M., Shono, S., Saito, A., Okamura, Y., Saitoh, D., Takeoka, S
- Journal Title
  
  Surgery
  
  Volume: 148 Pages: 48-58
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Immunosuppression in the livers of mice with obstructive jaundice participates in their susceptibility to bacterial infection and tumor metastasis2010
- Author(s)
  Kawarabayashi, N., Seki, S., Hatsuse, K., Kinoshita, M., Takigawa, T., Tsujimoto, H., Kawabata, T., Nakashima, H., Shono, S., and Mochizuki, H
- Journal Title
  
  SHOCK
  
  Volume: 33 Pages: 500-506
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] The effect of ketamine anesthesia on the immune function of mice with postoperative septicemia2010
- Author(s)
  Takahashi, T., Kinoshita, M., Shono, S., Habu, Y., Ogura, T., Seki S., Kazama, T
- Journal Title
  
  Anesth Analg
  
  Volume: 111 Pages: 1051-1058
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Characteriation of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice2010
- Author(s)
  Kinoshita, M., Uchida, T., Sato, A., Nakashima, M., Nakashima H., Shono S., Habu, Y., Miyazaki, H., Hiroi, S., Seki, S
- Journal Title
  
  J. Hepatol
  
  Volume: 53 Pages: 903-910
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] The effect of synthetic C-reactive protein on the in vitro immune response of human PBMCs stimulated with bacterial reagents
- Author(s)
  Sato A, Nakashima H, Kinoshita M, Nakashima M, Ogawa Y, Shono S, Ikarashi M, Seki S
- Journal Title
  
  Inflammation
- NAID
  130004638709
- Data Source
  KAKENHI-PROJECT-22592027
[Journal Article] Effective control of massive venous bleeding by "multi-overlapping therapy" using polysaccharide nanosheets in rabbit inferior vena cava injury model
- Author(s)
  Hagisawa K, Saito A, Kinoshita M, Fujie T, Otani N, Shono S, Park YK, Takeoka S
- Journal Title
  
  J. Vasc. Surg.
- Data Source
  KAKENHI-PROJECT-22592027
[Presentation] 腹部外科疾患から派生する敗血症の病態とDICの治療戦略2023
- Author(s)
  小野　聡
- Organizer
  Asahi Gastrointestinal Surgery Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 急性汎発性腹膜炎手術の治療戦略2023
- Author(s)
  小野　聡
- Organizer
  北海道最新知見up dateセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] PTGBD処置を契機にショック状態に陥ったClostridium perfringensが原因と思われる急性胆嚢炎の一例2023
- Author(s)
  加藤琢也、青笹季文、石川達郎、高藤康、内山真、島内貴弘、秋元寿文、野田和雅、岩本一亜、小野　聡
- Organizer
  第３６回日本外科感染症学会総会学術集会
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 外科侵襲とがんの転移・再発のメカニズムに迫る2023
- Author(s)
  小野　聡
- Organizer
  DIC治療講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 外科感染症学からみたがん・敗血症患者の長期予後2023
- Author(s)
  小野　聡
- Organizer
  第３６回日本外科感染症学会総会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 腹部重症感染症の治療戦略2022
- Author(s)
  小野　聡
- Organizer
  福島周術期管理WEBセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 敗血症病態・治療の変遷-エンドトキシンをターゲットにした治療戦略-2022
- Author(s)
  小野　聡
- Organizer
  第25回エンドトキシン血症救命治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 急性汎発性腹膜炎手術の周術期管理2022
- Author(s)
  小野　聡
- Organizer
  多摩西南消化器DIC seminar
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 敗血症病態・治療の変遷-エンドトキシンをターゲットにした治療戦略-2022
- Author(s)
  小野　聡
- Organizer
  第25回エンドトキシン血症救命治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 敗血症性DICと血管内皮細胞傷害2022
- Author(s)
  小野　聡
- Organizer
  第４回さいたま県北敗血症治療セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 急性汎発性腹膜炎手術の周術期管理2022
- Author(s)
  小野　聡
- Organizer
  多摩西南消化器DIC seminar
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 敗血症診療ガイドライン(DICの治療に関して）2022
- Author(s)
  小野　聡
- Organizer
  外科救急online seminar in 北陸
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 敗血症性DICと血管内皮細胞傷害2022
- Author(s)
  小野　聡
- Organizer
  第４回さいたま県北敗血症治療セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 外科疾患でのsepsisの病態とDIC治療の意義2022
- Author(s)
  小野　聡
- Organizer
  第10回Sepsis学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 外科疾患でのsepsisの病態とDIC治療の意義2022
- Author(s)
  小野　聡
- Organizer
  第10回Sepsis学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 敗血症診療ガイドライン(DICの治療に関して）2022
- Author(s)
  小野　聡
- Organizer
  外科救急online seminar in 北陸
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 外科侵襲学からみた癌・敗血症患者の長期予後2022
- Author(s)
  小野　聡
- Organizer
  第866回外科集談会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 消化器外科領域での敗血症治療におけるDIC対策の重要性2022
- Author(s)
  小野　聡
- Organizer
  Digestive Surgery & Coagulation
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 消化器癌手術での術後感染性合併症が癌の長期予後に及ぼす影響2021
- Author(s)
  小野　聡、辻本広紀
- Organizer
  第３６回日本臨床栄養代謝学会学術集会（神戸）
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 急性汎発性腹膜炎手術の周術期管理2021
- Author(s)
  小野　聡
- Organizer
  腹部重症感染症の治療戦略webセミナー（横浜）
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 侵襲と生体反応2021
- Author(s)
  小野　聡
- Organizer
  第４8回日本集中治療医学会学術集会(神戸）
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 免疫抑制細胞集団に注目した新規敗血症治療戦略-PMXの役割について-2021
- Author(s)
  小野　聡
- Organizer
  第34回日本外科感染症学会総会・学術集会（小倉）
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 侵襲と生体反応2021
- Author(s)
  小野　聡
- Organizer
  第４8回日本集中治療医学会学術集会(神戸）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 急性汎発性腹膜炎手術の周術期管理2021
- Author(s)
  小野　聡
- Organizer
  腹部重症感染症の治療戦略webセミナー（横浜）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 免疫抑制細胞集団に注目した新規敗血症治療戦略-PMXの役割について-2021
- Author(s)
  小野　聡
- Organizer
  第34回日本外科感染症学会総会・学術集会（小倉）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 外科疾患での敗血症とDICの治療戦略2021
- Author(s)
  小野　聡
- Organizer
  第３６回救急シンポジウム（Web開催）　埼玉外科医会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09056
[Presentation] 侵襲と生体反応2020
- Author(s)
  小野　聡
- Organizer
  第４7回日本集中治療医学会学術集会(名古屋）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 腹腔内感染から派生する臓器障害の病態と治療2020
- Author(s)
  小野　聡
- Organizer
  日本救急医学会総会・学術集会（岐阜）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 消化器外科疾患での敗血症とDICの治療戦略2020
- Author(s)
  小野　聡
- Organizer
  福島消化器外科フォーラム2020
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 外科侵襲学からみたsepsis患者の長期予後2019
- Author(s)
  小野　聡
- Organizer
  高知重症感染症セミナー（高知）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 血液凝固線溶系とがん手術患者の長期予後2019
- Author(s)
  小野　聡
- Organizer
  第4回山陰外科DICフォーラム（米子）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] （ワークショップ）敗血症性免疫不全の病態解明と新規治療法2019
- Author(s)
  小野　聡、青笹季文、辻本広紀、島内貴弘、秋元寿文、宮田剛彰、志田晴彦
- Organizer
  第81回日本臨床外科学会総会（高知）
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 外科侵襲学からみた癌・敗血症患者の長期予後2019
- Author(s)
  小野　聡
- Organizer
  第８回埼玉西部敗血症治療セミナー(川越）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 消化器疾患での敗血症とDICの治療戦略2019
- Author(s)
  小野　聡
- Organizer
  日本消化器病学会九州支部例会（宮崎）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] がん手術患者の周術期免疫能と長期予後2019
- Author(s)
  小野　聡
- Organizer
  群馬侵襲治療フォーラム(前橋）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] がん手術患者の周術期免疫能と長期予後2018
- Author(s)
  小野　聡
- Organizer
  第84回千葉県外科医会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 血液凝固線溶系とがん手術患者の長期予後2018
- Author(s)
  小野　聡
- Organizer
  第5回北海道Acute Care Academy
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] (外科感染症入門講座）外科術前術後の免疫能と術後合併症2018
- Author(s)
  小野　聡
- Organizer
  第31回日本外科感染症学会総会学術集会(大阪）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 周術期管理の進歩はがん手術患者の長期予後を改善するか2018
- Author(s)
  小野　聡
- Organizer
  第４回南多摩外科感染症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 外科侵襲学からみたsepsis患者の長期予後2018
- Author(s)
  小野　聡
- Organizer
  北里集中治療カンファランス(北里大学）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 周術期管理とがん手術患者の長期予後2018
- Author(s)
  小野　聡
- Organizer
  第7回臨床外科ジョイントフォーラム(新宿）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] (シンポジウム）血液浄化療法と免疫　敗血症性免疫不全対策としての血液浄化療法の意義2018
- Author(s)
  小野　聡、須田慎吾、奈倉武郎、池田寿昭
- Organizer
  第29回日本急性血液浄化学会学術集会（名古屋）
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 血液凝固線溶系とがん手術患者の長期予後2018
- Author(s)
  小野　聡
- Organizer
  Thoracic Surgery Thrombomodulin Seminar(広島）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] (パネルディスカッション）敗血症性免疫不全対策としてのエンドトキシン吸着療法(PMX-DHP)の意義に関する基礎的研究2018
- Author(s)
  小野　聡、須田慎吾、奈倉武郎、木村暁史、池田寿昭
- Organizer
  第４５回日本集中治療医学会学術集会(幕張）
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 敗血症性免疫不全の病態解析と新たな治療戦略2017
- Author(s)
  小野　聡、須田慎吾、奈倉武郎、池田寿昭
- Organizer
  第４５回日本救急医学会総会・学術集会(大阪）
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 敗血症性免疫不全の病態と今後の治療戦略2017
- Author(s)
  小野　聡
- Organizer
  第22回新都心集中治療カンファレンス
- Place of Presentation
  新宿京王プラザホテル
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] sepsisの新しい定義とDIC対策2017
- Author(s)
  小野　聡
- Organizer
  5回埼玉東部敗血症治療セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 消化器外科周術期の感染管理2017
- Author(s)
  小野　聡
- Organizer
  多摩感染症セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 敗血症性免疫不全の病態と今後の治療戦略2017
- Author(s)
  小野　聡
- Organizer
  第22回新都心集中治療カンファレンス（新宿）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 急性汎発性腹膜炎手術の周術期管理2017
- Author(s)
  小野　聡
- Organizer
  第72回日本消化器外科学会総会(金沢）
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] 外科的感染症のDNA診断・血清診断の有用性2017
- Author(s)
  小野　聡、須田慎吾、奈倉武郎、池田寿昭
- Organizer
  第４４回日本集中治療医学会学術集会
- Place of Presentation
  札幌市教育文化会館
- Year and Date
  2017-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] 集中治療と感染症　外科的感染症のDNA診断・血清診断の有用性2017
- Author(s)
  小野　聡、須田慎吾、奈倉武郎、上野琢哉、池田寿昭
- Organizer
  第４４回日本集中治療医学会学術集会（札幌）
- Invited
- Data Source
  KAKENHI-PROJECT-17K10524
[Presentation] sepsisの新しい定義を読み解く2016
- Author(s)
  小野　聡
- Organizer
  第25回日本集中治療医学会関東甲信越地方会
- Place of Presentation
  帝京大学
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] Sepsisの新しい定義とsepsis治療の新たな展開2016
- Author(s)
  小野　聡
- Organizer
  セプシスカンファレンスin広島2016
- Place of Presentation
  広島
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] 術後感染症と腸管免疫2016
- Author(s)
  小野　聡
- Organizer
  第29回日本外科感染症学会総会
- Place of Presentation
  新宿京王プラザホテル
- Year and Date
  2016-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] 外科からみた周術期感染管理2015
- Author(s)
  小野　聡
- Organizer
  第２１３回ICD講習会
- Place of Presentation
  東京
- Year and Date
  2015-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] （シンポジウム）外科侵襲時の炎症・免疫担当細胞の役割と機能評価2015
- Author(s)
  小野　聡、辻本広紀、平木修一、久保　徹、池田寿昭
- Organizer
  外科代謝栄養学会第52回学術集会
- Place of Presentation
  品川
- Year and Date
  2015-07-03
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] Burn evoked ROS immediately after injury are crucial to rescue the neutrophil function against post-burn infection in mice2015
- Author(s)
  Kinoshita M, Miyazaki H, Ono S, Hagisawa K, Seki S, Saitoh D.
- Organizer
  38th Annual congress on Shock
- Place of Presentation
  Denver, USA
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462773
[Presentation] 外科侵襲と腸管免疫2015
- Author(s)
  小野　聡
- Organizer
  第21回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  東京
- Year and Date
  2015-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] 重症敗血症治療におけるサイトカイン治療の新たな展開2015
- Author(s)
  小野　聡
- Organizer
  サイトカインストーム研究会
- Place of Presentation
  宇都宮
- Year and Date
  2015-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] 小児腹膜炎における汚染手術での術後癒着軽減への挑戦～ PLAナノシートの癒着防止効果の特徴～2015
- Author(s)
  檜顕成, 齋藤晃広, 木下学, 谷水長丸, 宮崎裕美, 北川大輝, 小岩井和樹, 青笹季文,山崎民大, 守屋智之, 野呂拓史, 小野聡, 齋藤大蔵, 武岡真司, 長谷和生, 山本順司
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25462844
[Presentation] Burn-evoked ROS immediately after injury are crucial to rescue the neutrophil function against post-burn infection in mice2015
- Author(s)
  Kinoshita M, Miyazaki H, Ono S, Hagisawa K, Saitoh D, Seki S,
- Organizer
  38th Annual congress on Shock
- Place of Presentation
  Denver CO
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293369
[Presentation] 白血球数はPMX-DHPの効果に影響を及ぼすか？2015
- Author(s)
  山中浩史、池田寿昭、小野　聡、上野琢哉、須田慎吾
- Organizer
  第42回日本集中治療医学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-02-09
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] 敗血症時の免疫機能低下の病態とモニタリング2015
- Author(s)
  小野　聡
- Organizer
  敗血症セミナー in 名古屋
- Place of Presentation
  名古屋大学
- Year and Date
  2015-01-10
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] 敗血症性DICの病態解明とその対策2015
- Author(s)
  小野　聡
- Organizer
  広島DICフォーラム2015
- Place of Presentation
  広島
- Year and Date
  2015-06-19
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] 外科侵襲後の免疫応答の病態解析とその対策に関する研究2014
- Author(s)
  小野聡, 辻本広紀, 平木修一, 木下学,
- Organizer
  第113回日本外科学会定期学術集会シンポジウム
- Place of Presentation
  京都
- Year and Date
  2014-04-03
- Data Source
  KAKENHI-PROJECT-25293369
[Presentation] 超薄膜ナノシートを応用した熱傷治療2014
- Author(s)
  宮崎裕美, 木下学, 小野聡
- Organizer
  第40回日本熱傷学会総会
- Place of Presentation
  さいたま
- Year and Date
  2014-06-04
- Data Source
  KAKENHI-PROJECT-25293369
[Presentation] 外科侵襲後の生体反応の特性と対策2014
- Author(s)
  小野　聡
- Organizer
  産業医科大学学内講演会
- Place of Presentation
  北九州市
- Invited
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 人工赤血球や人工血小板などの血液代替物の開発とその将来展望2014
- Author(s)
  木下学、萩沢康介、西川可穂子、柳川錬平、小野　聡、齋藤大蔵、高瀬凡平、酒井宏水、半田誠、武岡真司、関修司
- Organizer
  第114回日本外科学会定期学術集会　(パネルデスカッション1-3)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293369
[Presentation] 敗血症性免疫不全状態におけるエンドトキシン吸着療法(PMX)の有効性発現機序に関する基礎的研究2014
- Author(s)
  木村暁史、小野　聡、辻本広紀、平木修一、高畑りさ、青笹季文、初瀬一夫、齋藤大蔵、長谷和生、山本順司
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都国際会議場
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] (ランチョン）血液凝固線溶系の変動と免疫応答からみた外傷後の生体反応の特性2013
- Author(s)
  小野　聡
- Organizer
  第27回日本外傷学会総会・学術集会
- Place of Presentation
  久留米
- Invited
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 糖尿病マウスでの創部感染増悪への好中球機能不全の関与トインスリン治療2013
- Author(s)
  木下学、矢野秀和、小野聡、浜田耕司、田中祐司、関修司
- Organizer
  第50回日本外科代謝栄養学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293369
[Presentation] (シンポジウム）外科侵襲後の免疫応答の病態解析とその対策に関する研究2013
- Author(s)
  小野　聡、辻本広紀、平木修一、高畑りさ、木村暁史、久保　徹、松本佑介、吉田一路、堀口寛之、野村信介、青笹季文、木下　学、山本順司、長谷和生、齋藤大蔵
- Organizer
  第113回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 免疫機能からみた周術期管理のトピックスｰ腸管は本当に重要か-2013
- Author(s)
  小野　聡
- Organizer
  第11回秋田県NST研究会
- Place of Presentation
  秋田市
- Invited
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 手術侵襲の軽減は癌の長期予後を改善するか？2013
- Author(s)
  小野　聡
- Organizer
  兵庫県消化器外科研究会2013
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 熱傷などの重度外科侵襲に続発する複合免疫不全病態とIL-18による免疫賦活.2013
- Author(s)
  木下学、宮崎裕美、小野聡、関修司
- Organizer
  第26回日本外科感染症学会総会(パネルデスカッション)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25293369
[Presentation] 外科侵襲後の免疫応答の病態解析とその対策に関する研究2013
- Author(s)
  小野聡、辻本広紀、木下学、長谷和生、齋藤大蔵, 他
- Organizer
  第113回日本外科学会定期学術集会
- Place of Presentation
  福岡(シンポジウム)
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 消化器外科周術期の病態解析におけるEndotoxin Activity Assay測定の意義に関する検討2013
- Author(s)
  小野　聡、久保　徹、高畑りさ、木村暁史、松本佑介、吉田一路、平木修一、辻本広紀、青笹季文、長谷和生
- Organizer
  第68回日本消化器外科学会総会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] The Predictive Value of Endotoxin Activity Assay for The Incidence of Postoperative Infectious Complications Following Elective Gastrointestinal Surgery2013
- Author(s)
  Ono S, Miyazaki H, Tsujimoto H, Kinoshita M, Hase K, Saitoh D, et al.
- Organizer
  Thirty-sixth Annual Conference on Shock
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 消化器外科周術期の病態形成における制御性T細胞の役割とその対策に関する検討2012
- Author(s)
  小野　聡、平木修一、辻本広紀、高畑りさ、松本佑介、木村暁史、久保　徹、熊野　勲、吉田一路、長谷和生
- Organizer
  第67回日本消化器外科学会総会
- Place of Presentation
  富山国際会議場
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 外科系学会における侵襲学研究の位置づけと今後の展望2012
- Author(s)
  小野聡
- Organizer
  第27回日本Shock学会
- Place of Presentation
  東京(シンポジウム)
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 外科侵襲後の生体反応における免疫不全の病態解析とその対策に関する検討2012
- Author(s)
  小野聡、辻本広紀、宮崎裕美、木下学、長谷和生、齋藤大蔵, 他
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉(パネルディスカッション)
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 消化器外科周術期の病態形成における制御性T細胞の役割とその対策に関する検討2012
- Author(s)
  小野聡、辻本広紀、長谷和生, 他
- Organizer
  第67回日本消化器外科学会総会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 免疫機能からみた周術期管理のトピックス2012
- Author(s)
  小野　聡
- Organizer
  横浜周術期管理フォーラム2012
- Place of Presentation
  横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] （パネルディスカッション）外科侵襲後の生体反応における免疫不全の病態解析とその対策に関する検討2012
- Author(s)
  小野　聡、辻本広紀、平木修一、高畑りさ、木村暁史、矢口義久、熊野　勲、松本佑介、吉田一路、堀口寛之、宮崎裕美、木下　学、山本順司、長谷和生、齋藤大蔵
- Organizer
  第112回日本外科学会定期学術集会（千葉）
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 重症敗血症の病態解析における多項目サイトカイン同時測定の意義2011
- Author(s)
  小野　聡、辻本広紀、平木修一、高畑りさ、木村暁史、矢口義久、松本佑介、吉田一路、野村信介、木下　学、宮庄拓、山本順司、長谷和生、齋藤大蔵
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] 敗血症患者の病態と免疫機能2011
- Author(s)
  小野　聡
- Organizer
  第11回甲信急性血液浄化療法研究会(招待講演)
- Place of Presentation
  甲府
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] Pioglitazone Improves Mouse Survival After Post-Burn Bacterial Infection Via Restoration of Kupffer Cell Function2011
- Author(s)
  Miyazaki H, Kinoshita M, Ono S, Seki S, Saitoh D
- Organizer
  18th Annual Meeting of Society for Free Radical Biology and Medicine
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-22592027
[Presentation] 敗血症の新たな治療戦略2011
- Author(s)
  小野　聡
- Organizer
  外科領域における敗血症治療を考える会(招待講演)
- Place of Presentation
  川越市
- Data Source
  KAKENHI-PROJECT-23591886
[Presentation] Interleukin-18 treatment following burn injury activates Kupffer cell phagocytosis in mice2010
- Author(s)
  Miyazaki H, Kinoshita M, Ono S, Hara E, Takagi T, Seki S, Saitoh D
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe Japan
- Data Source
  KAKENHI-PROJECT-22592027
[Presentation] Interleukin-18 therapy enhances Kupffer cell-mediated bacterial elimination in post-burn infection models via the activation of NK cell function2010
- Author(s)
  Kinoshita M, Shinomiya N, Miyazaki H, Ono S, Saitoh D, Seki S
- Organizer
  Chemical and Biological Defense Science and Technology (CBD S&T) 2010
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-22592027
[Presentation] Activation of NK cells by IL-18 augments bacterial elimination by Kupffer cells in the burn-injured mice2010
- Author(s)
  Miyazaki H, Kinoshita M, Ono S, Nakashima M, Hara E, Ohno H, Seki S, Daizoh D
- Organizer
  Society for Free Radical Biology and Medicine 17th Annual Meeting
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-22592027
[Presentation] Activation of liver innate immune lymphocytes and Kupffer cells in mice fed with a high fat and cholesterol diet.2010
- Author(s)
  Shono, S
- Organizer
  14th International Congress of Immunology.
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-22592027
[Presentation] Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice2010
- Author(s)
  Kinoshita M, Uchida T, Sato A, Nakashima M, Nakashima H, Shono S, Habu Y, Miyazaki H, Seki S
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe Japan
- Data Source
  KAKENHI-PROJECT-22592027
[Presentation] （教育セミナー）免疫機能からみた術後感染性合併症のリスク評価と予測因子に関する検討
- Author(s)
  小野　聡、久保　徹、高畑りさ、木村暁史、辻本広紀、青笹季文、長谷和生
- Organizer
  第27回日本外科感染症学会総会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-12-03 – 2014-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-26670795
[Presentation] 同種皮膚を用いた新規熱傷治療法　―マイクロスキンとナノシートの併用療法－
- Author(s)
  宮崎裕美、安西一正、小野聡、木下学、齋藤晃広、武岡真司、齋藤大蔵
- Organizer
  第39回日本熱傷学会総会・学術集会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-25462844
[Presentation] Application of a biodegradable nanosheet as a new dressing for burn wounds
- Author(s)
  Miyazaki H, Kinoshita M, Ono S, Fujie T, Takeoka S, Saitoh　D.
- Organizer
  17th Congress of International Society for Burns Injuries
- Place of Presentation
  Sydney (Australia)
- Year and Date
  2014-10-14 – 2014-10-16
- Data Source
  KAKENHI-PROJECT-25462844
[Presentation] パネルディスカッション熱傷基礎研究の最前線超薄膜ナノシートを応用した熱傷治療
- Author(s)
  宮崎裕美、木下学、小野聡、武岡真司、齋藤大蔵
- Organizer
  第40回日本熱傷学会総会・学術集会
- Place of Presentation
  ラフレ埼玉（埼玉）
- Year and Date
  2014-06-05 – 2014-06-06
- Invited
- Data Source
  KAKENHI-PROJECT-25462844
[Presentation] Burn-evoked reactive oxygen species immediately after injury are important to restore the neutrophil function against post-burn infection in mice
- Author(s)
  宮崎裕美、木下学、小野聡、関修司、齋藤大蔵
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26462773

1. KINOSHITA Manabu (70531391)

# of Collaborated Projects: 17 results

# of Collaborated Products: 73 results
2. MIYAZAKI Hiromi (30531636)

# of Collaborated Projects: 13 results

# of Collaborated Products: 51 results
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37. 城田千代栄 (20378194)

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38. 大澤勲 (60407252)

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39. 村越貴子 (70573666)

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40. 大越絵実加 (10287667)

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41. 亀井康富 (70300829)

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42. 小野岳史 (20535182)

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43. ISHIKAWA Takashi

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44. 土田英俊

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# of Collaborated Products: 6 results
45. 小田美規

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ono satoshi 小野 聡

ONO Satoshi 小野 聡

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重症病態での免疫抑制細胞集団の解析とその制御Principal Investigator

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Pathophysiological analysis of immunodeficiency in critical illnessPrincipal Investigator

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Blood purification for sepsis-induced immunoparalysisPrincipal Investigator

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ono satoshi 小野聡

ONO Satoshi 小野聡

[Book] 術後ケアとドレーン管理のすべて　編集：竹末芳生、藤野智子2016

[Book] 敗血症（セプシス）救命治療の最前線　竹末芳生編　セプシス治療薬　セプシス治療薬の日本での活用2014

[Book] 敗血症（セプシス）　救命治療の最前線　セプシス治療薬の日本での活用2014

[Book] 周術期感染管理テキスト　重症敗血症、敗血症性ショック2012

[Journal Article] 特集：ICUで遭遇する免疫異常　正常な免疫機能-自然免疫、獲得免疫の基本的な役割と機能-2023