Negoro Hiromitsu 根来宏光

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NEGORO Hiromitsu 根来宏光

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Researcher Number	80708595
Other IDs	https://orcid.org/0000-0003-1144-2755
Affiliation (Current)	2025: 筑波大学, 医学医療系, 特任教授
Affiliation (based on the past Project Information) *help	2025: 筑波大学, 医学医療系, 特任教授 2021 – 2024: 筑波大学, 医学医療系, 准教授 2019 – 2020: 筑波大学, 医学医療系, 講師 2018 – 2019: 筑波大学, 附属病院, 病院講師 2016 – 2017: 京都大学, 医学研究科, 助教 2016: 京都大学, 医学研究科, 特定助教 2013 – 2016: 京都大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology / Environmental physiology(including physical medicine and nutritional physiology) Except Principal Investigator Basic Section 56030:Urology-related / Urology / Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
Keywords	Principal Investigator 概日時計 / 膀胱 / 時間生物学 / コネキシン43 / 尿路上皮 / 機能 / 末梢時計 / 放射線保護 / 放射線 / 下部尿路症状 … More / 睡眠障害 / 日内リズム / 睡眠 / 排尿 / 概日リズム / コネキシン / コネキシン４３ / ATP / 時計遺伝子 / Bmal1 / 排尿障害 / ヘミチャネル / 体内時計 … More Except Principal Investigator 低活動膀胱 / 膀胱癌 / PA / 腎癌 / 前立腺癌 / 質量分析 / がん免疫微小環境 / 尿路上皮癌 / 廃用性萎縮 / 膀胱機能回復 / 骨盤神経損傷モデル / アデノシン / アンメットメディスン / ラットモデル / コリンエステラーゼ阻害剤 / アデノシン受容体 / 骨盤神経損傷 / アデノシン受容体シグナル / アニマルモデル / アデノシンレセプター / 寝室 / 予後 / 睡眠障害 / 光害 / 認知機能 / がん / メラトニン / アクチグラフ / うつ / 肥満 / 睡眠 / うつ症状 / 動脈硬化 / 糖尿病 / サーカディアンリズム / 体内時計 / 光曝露 / 浸潤 / アンギオゲニン / ホスホリパーゼD / MMP-13 / がん微小環境 / 腫瘍浸潤 / PLD2 / PLD1 / 概日リズム / フラボノイド系化合物 / ノビレチン / 時計遺伝子 / 夜間頻尿 / mTOR / 生理活性脂質 / ホスファチジン酸 / リゾホスファチジルコリン / 脂質 / バイオマーカー / 治療抵抗性 / プロテオミクス / 癌 / xenograft / omics Less

A Novel Therapeutic Approach for Nocturia Using a Model of Bladder Diurnal Rhythm Disruption by the Circadian ClockPrincipal Investigator
- Principal Investigator
  
  根来宏光
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
尿路変向による廃用性低活動萎縮膀胱ラットモデルの回復における神経支配の影響の解明
- Principal Investigator
  
  井上高光
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  International University of Health and Welfare
Elucidation of the mechanism of reduction of bladder injury caused by radiotherapy and chronobiological approach to the development of new preventive methods.Principal Investigator
- Principal Investigator
  
  根来宏光
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
尿路上皮癌モデルを用いた細胞アトラス構築を基盤とした免疫相関機序の解明と臨床応用
- Principal Investigator
  
  西山博之
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
Pathophysiological investigation of the hypoactive bladder using multiple models caused by defunctionalization, neurogenic, and obstruction
- Principal Investigator
  
  井上高光
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  International University of Health and Welfare
To elucidate the pathophysiological mechanism and explore the therapeutic target of underactive bladder / detrusor underactivity with focusing on the adenosine signaling pathway
- Principal Investigator
  
  高岡栄一郎
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Jichi Medical University
  International University of Health and Welfare
Investigation into the mechanism of lower urinary tract dysfunction due to sleep disorder focusing on bladder clockPrincipal Investigator
- Principal Investigator
  
  Negoro Hiromitsu
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
Lipid metabolism-mediated mechanisms of bladder cancer invasion in the cancer microenvironment
- Principal Investigator
  
  Kawai Koji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  International University of Health and Welfare
  University of Tsukuba
Long-term Effect of Light Exposure on Health Outcomes
- Principal Investigator
  
  OBAYASHI KENJI
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  Nara Medical University
Elucidation of the bladder clock function using flavonoids and its application for timed therapy in nocturia patients
- Principal Investigator
  
  ITO Haruki
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
A chronobiological approach to elucidate nocturia focusing on the urotheliumPrincipal Investigator
- Principal Investigator
  
  Negoro Hiromitsu
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Urology
- Research Institution
  University of Tsukuba
  Kyoto University
Search for innovative diagnostic and therapeutic seeds based on next generation OMICS analysis using new disease models
- Principal Investigator
  
  Ogawa Osamu
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Urology
- Research Institution
  Kyoto University
The exploration of bioactive lipids related to progression of cancer by the next generation mass spectrometry based lipidomics
- Principal Investigator
  
  Yamasaki Toshinari
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kyoto University
Diurnal change of urothelial function focusing on the hemichannel of connexin43Principal Investigator
- Principal Investigator
  
  NEGORO Hiromitsu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

[Book] 適正使用のための臨床時間薬理学生体リズムと薬物治療効果2022
- Author(s)
  根来宏光
- Total Pages
  6
- Publisher
  診断と治療社
- ISBN
  9784787824844
- Data Source
  KAKENHI-PROJECT-20K18086
[Journal Article] Effectiveness and Safety of a Mixture of Nobiletin and Tangeretin in Nocturia Patients: A Randomized, Placebo-Controlled, Double-Blind, Crossover Study2023
- Author(s)
  Ito Haruki、Negoro Hiromitsu、Kono Jin、Hayata Naoki、Miura Takayoshi、Manabe Yumi、Miyazaki Yu、Mishina Mutsuki、Woo Je Tae、Sakane Naoki、Okuno Hiroshi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 8 Pages: 2757-2757
- DOI
  10.3390/jcm12082757
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09154
[Journal Article] Association Between Before-bedtime Passive Body Heating and Nocturia During the Cold Season Among Older Adults2023
- Author(s)
  Tai Yoshiaki、Obayashi Kenji、Okumura Kazuki、Yamagami Yuki、Negoro Hiromitsu、Kurumatani Norio、Saeki Keigo
- Journal Title
  
  Journal of Epidemiology
  
  Volume: 33 Issue: 8 Pages: 398-404
- DOI
  10.2188/jea.JE20210471
- NAID
  130008161541
- ISSN
  0917-5040, 1349-9092
- Year and Date
  2023-08-05
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15899, KAKENHI-PROJECT-21K17310, KAKENHI-PROJECT-20K10476, KAKENHI-PROJECT-19H03903
[Journal Article] Glucocorticoids coordinate the bladder peripheral clock and diurnal micturition pattern in mice.2023
- Author(s)
  Chihara I, Negoro H, Kono J, Nagumo Y, Tsuchiya H, Kojo K, Shiga M, Tanaka K, Kandori S, Mathis BJ, Nishiyama H
- Journal Title
  
  Commun Biol
  
  Volume: 6 Issue: 1 Pages: 81-81
- DOI
  10.1038/s42003-023-04464-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09491
[Journal Article] Urothelium-Specific Deletion of Connexin43 in the Mouse Urinary Bladder Alters Distension-Induced ATP Release and Voiding Behavior2021
- Author(s)
  Kono Jin、Ueda Masakatsu、Sengiku Atsushi、Suadicani Sylvia O.、Ogawa Osamu、Negoro Hiromitsu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 4 Pages: 1594-1594
- DOI
  10.3390/ijms22041594
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18086
[Journal Article] PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer2021
- Author(s)
  Nagumo Yoshiyuki、Kandori Shuya、Tanuma Kozaburo、Nitta Satoshi、Chihara Ichiro、Shiga Masanobu、Hoshi Akio、Negoro Hiromitsu、Kojima Takahiro、Mathis Bryan J.、Funakoshi Yuji、Nishiyama Hiroyuki
- Journal Title
  
  Cancer Letters
  
  Volume: 511 Pages: 15-25
- DOI
  10.1016/j.canlet.2021.04.014
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09705, KAKENHI-PROJECT-17K07327
[Journal Article] Diurnal rhythms of urine volume and electrolyte excretion in healthy young men under differing intensities of daytime light exposure.2021
- Author(s)
  Nakamoto I, Uiji S, Okata R, Endo H, Tohyama S, Nitta R, Hashimoto S, Matsushima Y, Wakimoto J, Hashimoto S, Nishiyama Y, Kanikowska D, Negoro H, Wakamura T
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 13097-13097
- DOI
  10.1038/s41598-021-92595-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18086
[Journal Article] 特集朝まで待てない! 夜間頻尿完全マスター〈夜間頻尿の疫学と病態〉サーカディアンリズムと夜間頻尿2021
- Author(s)
  根来宏光
- Journal Title
  
  臨床泌尿器科
  
  Volume: 75 Issue: 1 Pages: 36-41
- DOI
  10.11477/mf.1413207098
- ISSN
  0385-2393, 1882-1332
- Year and Date
  2021-01-20
- Data Source
  KAKENHI-PROJECT-20K18086
[Journal Article] Sleep disturbance worsens lower urinary tract symptoms (LUTS): The Nagahama study2019
- Author(s)
  Fukunaga Arinobu、Kawaguchi Takahisa、Funada Satoshi、Yoshino Takayuki、Tabara Yasuharu、Matsuda Fumihiko、Yoshimura Koji、Ogawa Osamu、Negoro Hiromitsu、on behalf of the Nagahama Study Group
- Journal Title
  
  Journal of Urology
  
  Volume: in press Issue: 2 Pages: 354-354
- DOI
  10.1097/ju.0000000000000212
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04123, KAKENHI-PROJECT-15H05682
[Journal Article] Circadian coordination of ATP release in the urothelium via connexin43 hemichannels2018
- Author(s)
  Sengiku A, Ueda M, Kono J, Sano T, Nishikawa N, Kunisue S, Tsujihana K, Liou L, Kanematsu A, Shimba S, Doi M, Okamura H, Ogawa O, and Negoro H
- Journal Title
  
  Sci. Rep.
  
  Volume: 8 Issue: 1 Pages: 1996-1996
- DOI
  10.1038/s41598-018-20379-0
- NAID
  120006510288
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05933, KAKENHI-PROJECT-17H01524, KAKENHI-PROJECT-15H05682, KAKENHI-PROJECT-17K08291
[Journal Article] Epidemiology, pathophysiology and diagnosis of nocturia2018
- Author(s)
  Negoro H
- Journal Title
  
  Japanese Journal of Clinical Urology
  
  Volume: 72 Pages: 104-110
- NAID
  40021455399
- Open Access
- Data Source
  KAKENHI-PROJECT-15H05682
[Journal Article] <b>Circadian rhythms of micturition during jet </b><b>lag </b>2018
- Author(s)
  Ito K, Yasuda M, Maeda Y, Fustin JM, Yamaguchi Y, Kono Y, Negoro H, Kanematsu A, Ogawa O, Doi M, and Okamura H
- Journal Title
  
  Biomed. Res.
  
  Volume: 39 Issue: 2 Pages: 57-63
- DOI
  10.2220/biomedres.39.57
- NAID
  130006708567
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05933, KAKENHI-PROJECT-15H01843, KAKENHI-PROJECT-17H01524, KAKENHI-PROJECT-15H05642, KAKENHI-PROJECT-15H05682, KAKENHI-PROJECT-20K20302
[Journal Article] [Biological clock and nocturia]2018
- Author(s)
  Negoro H, Sengiku A
- Journal Title
  
  Journal of Clinical and Experimental Medicine
  
  Volume: 267 Pages: 457-461
- NAID
  40021711911
- Data Source
  KAKENHI-PROJECT-15H05682
[Journal Article] Cross-Sectional Epidemiological Analysis of the Nagahama Study for Correlates of Overactive Bladder: Genetic and Environmental Considerations.2017
- Author(s)
  Funada S. Kawaguchi T. Terada N. Negoro H. Tabara Y. Kosugi S. Yamada R. Nakayama T. Akamatsu S. Yoshimura K. Matsuda F. Ogawa O. Nagahama Study Group.
- Journal Title
  
  J Urol.
  
  Volume: in press Issue: 3 Pages: 774-778
- DOI
  10.1016/j.juro.2017.09.146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04123, KAKENHI-PROJECT-15H05682, KAKENHI-PROJECT-15K08646
[Journal Article] Nocturia increases the incidence of depressive symptoms: a longitudinal study of the HEIJO-KYO cohort.2017
- Author(s)
  Obayashi K, Saeki K, Negoro H, Kurumatani N
- Journal Title
  
  BJU Int
  
  Volume: 120 Pages: 280-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05682
[Journal Article] Dietary Sodium Restriction Reduces Nocturnal Urine Volume and Nocturnal Polyuria Index in Renal Allograft Recipients With Nocturnal Polyuria.2017
- Author(s)
  Okumura Y, Asai K, Kobayashi T, Miyata H, Tanaka Y, Okada Y, Sakai K, Kamba T, Tsuji H, Shide K, Nagashima K, Yanagita M, Inagaki N, Ogawa O, Negoro H
- Journal Title
  
  Urology
  
  Volume: 106 Pages: 60-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05682
[Journal Article] 概日リズムと排尿機能2017
- Author(s)
  根来宏光
- Journal Title
  
  腎臓内科・泌尿器科
  
  Volume: ６ Pages: 154-158
- NAID
  40021296395
- Data Source
  KAKENHI-PROJECT-15H05682
[Journal Article] Intravital imaging of mouse urothelium reveals activation of extracellular signal-regulated kinase by stretch-induced intravesical release of ATP.2016
- Author(s)
  Sano T, Kobayashi T, Negoro H, Sengiku A, Hiratsuka T, Kamioka Y, Liou LS, Ogawa O, Matsuda M
- Journal Title
  
  Physiological reports
  
  Volume: 21 Issue: 21
- DOI
  10.14814/phy2.13033
- NAID
  120005895398
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05682, KAKENHI-PLANNED-15H05949
[Journal Article] Altered detrusor gap junction communications induce storage symptoms in bladder inflammation: a mouse cyclophosphamide-induced model of cystitis.2014
- Author(s)
  Okinami T, Imamura M, Nishikawa N, Negoro H, Sugino Y, Yoshimura K, Kanematsu A, Hashitani H, Ogawa O.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 8 Pages: e104216-e104216
- DOI
  10.1371/journal.pone.0104216
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25893100
[Journal Article] Pannexin 1 channels play essential roles in urothelial mechanotransduction and intercellular signaling.2014
- Author(s)
  Negoro H, Urban-Maldonado M, Liou LS, Spray DC, Thi MM, Suadicani SO.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 8 Pages: e106269-e106269
- DOI
  10.1371/journal.pone.0106269
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25893100
[Presentation] 過活動膀胱と夜間頻尿　疫学・基礎・臨床からのアプローチ2024
- Author(s)
  根来宏光
- Organizer
  第１１１回日本泌尿器科学会総会　ランチョンセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] 過活動膀胱と夜間頻尿　基礎・疫学・臨床からのアプローチ2024
- Author(s)
  根来宏光
- Organizer
  福井泌尿器科フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] 両側尿管膣吻合を用いたメスラット尿路変更による廃用性萎縮膀胱モデルの作成2024
- Author(s)
  井上高光、千原尉智蕗、根来宏光、西山博之、宮﨑淳
- Organizer
  第111回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-21K09379
[Presentation] 概日時計が影響する排尿制御とその破綻：疫学、基礎研究、臨床研究からの洞察2024
- Author(s)
  根来宏光
- Organizer
  自治医科大学大学院医学研究科特別講義
- Invited
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] 過活動膀胱と夜間頻尿　基礎・疫学、そして臨床へ2023
- Author(s)
  根来宏光
- Organizer
  第1回倉敷泌尿器疾患研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] Chronobiology of LUTS and Nocturia2023
- Author(s)
  Hiromitsu Negoro
- Organizer
  39th Japan-Korea Urological Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] 泌尿器科疾患におけるノビレチンへの期待2023
- Author(s)
  根来宏光
- Organizer
  第21回日本機能性食品医用学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] 概日リズムの異常と排尿障害ー膀胱のリズムから見えてくるものー2023
- Author(s)
  根来宏光
- Organizer
  第二回三重LUTSフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] 体内リズムからみた夜間頻尿の病態と治療2023
- Author(s)
  根来宏光
- Organizer
  第２５回岐阜排尿障害研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] Glucocorticoids control clock gene circadian rhythm in the bladder and modulate diurnal rhythm of volume voided per micturition.2023
- Author(s)
  Ichiro Chihara, Hiromitsu Negoro, Jin Kono, Haruki Tsuchiya, Yoshiyuki Nagumo, Hiroyuki Nishiyama
- Organizer
  第110回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] 膀胱時計調律因子の同定2023
- Author(s)
  千原尉智蕗, 根来宏光, 河野仁, 土屋春樹, 南雲義之, 神鳥周也, 西山博之
- Organizer
  第32回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] Glucocorticoid functions as a cue of bladder peripheral clock and influenced diurnal micturition pattern.2022
- Author(s)
  千原尉智蕗、根来宏光、河野仁、南雲義之、土屋春樹、古城公祐、志賀正宣、田中建、神鳥周也、西山博之
- Organizer
  第29回日本時間生物学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] Efficacy and safety of a mixture of Nobiletin and Tangeretin in patients with nocturia (NoT-N octuria study): A randomized, placebo-controlled, double-blind, crossover study2022
- Author(s)
  Ito H, Negoro H, Kono J, Igarashi A, Hayata N, Miura T, Manabe Y, Miyazaki Y, Mishina M, Woo J, Okuno H
- Organizer
  52th International Continence Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09154
[Presentation] 夜間頻尿患者に対するノビレチン・タンゲレチン混合物の効果と安全性に関する研究(NoT-nocturia study)：ランダム化プラセボ対照2重盲検化クロスオーバー比較試験2022
- Author(s)
  伊東晴喜、根来宏光、河野仁、渡邊岳之、早田直生、三浦高慶、真鍋由美、宮崎有、三品睦輝、禹済泰、奥野博
- Organizer
  第29回日本排尿機能学会
- Data Source
  KAKENHI-PROJECT-18K09154
[Presentation] CONTROL OF BLADDER PERIPHERAL CLOCK AND DIURNAL MICTURITION PATTERN BY GLUCOCORTICOIDS2022
- Author(s)
  CHIHARA I, NEGORO H, KONO Z, TSUCHIYA H, NAGUMO Y, NISHIYAMA H
- Organizer
  International Continence Society 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09491
[Presentation] 夜間頻尿と夜尿：概日リズムの視点から2021
- Author(s)
  根来宏光
- Organizer
  第７３回西日本泌尿器科学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K18086
[Presentation] 時間薬理学・時間治療の最新の知見『腎泌尿器科疾患の時間治療』2021
- Author(s)
  根来宏光
- Organizer
  第42回日本臨床薬理学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K18086
[Presentation] 概日リズムの破綻から夜尿と夜間頻尿を考える2021
- Author(s)
  根来宏光
- Organizer
  第29回日本小児泌尿器科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K18086
[Presentation] 夜間頻尿診療の最適化2021
- Author(s)
  根来宏光
- Organizer
  第８６回日本泌尿器科学会東部総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K18086
[Presentation] 排尿障害研究の魅力2021
- Author(s)
  根来宏光
- Organizer
  第１０９回泌尿器科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K18086
[Presentation] フラボノイド系化合物ノビレチンの膀胱時計遺伝子発現に対する影響2019
- Author(s)
  河野仁、根来宏光、上田政克、千菊敦士、小川修
- Organizer
  第26回時間生物学会
- Data Source
  KAKENHI-PROJECT-18K09154
[Presentation] 概日時計の破綻と夜間頻尿　－疫学・基礎からのアプローチ－2018
- Author(s)
  根来宏光
- Organizer
  第4回アカシア研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 夜間頻尿－その深淵に迫る　Circadian rhythmから夜間頻尿に迫る2018
- Author(s)
  根来宏光
- Organizer
  第106回日本泌尿器科学会総会　（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 体内時計から夜間頻尿を考える－疫学・基礎の視点から－2018
- Author(s)
  根来宏光
- Organizer
  第219回宮崎県泌尿器科医会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 尿路上皮のコネキシン43は時計遺伝子の制御下に細胞間情報伝達機能を有する2018
- Author(s)
  千菊敦士, 根来宏光, 上田政克, 河野仁, 佐野剛視, 國末純宏, 辻花光次郎, 岡村均, 小川修
- Organizer
  第27回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 体内時計の破綻と下部尿路症状‐タダラフィルの話題も交えて‐（講演）2018
- Author(s)
  根来宏光
- Organizer
  第８回熊本泌尿器疾患研究会2018.3.10
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 過活動膀胱の成因を考える（講演）2018
- Author(s)
  根来宏光
- Organizer
  女性泌尿器疾患を考える会2018.1.23
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] Insomnia induces lower urinary tract symptoms: The natural history and risk factors for LUTS from the Nagahama longitudinal study2018
- Author(s)
  Hiromitsu Negoro
- Organizer
  AUA 2018 Oral presentation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 夜間頻尿と睡眠障害の関係からみえてくるもの2018
- Author(s)
  根来宏光
- Organizer
  第 25 回日本排尿機能学会ランチョンセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] Medical history of nocturnal enuresis at school age is a risk factor for nocturia in adults: The Nagahama study2018
- Author(s)
  Hiromitsu Negoro
- Organizer
  EAU2019 (34th Annual European Association Of Urology Congress)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 体内時計の破綻と夜間頻尿（講演）2018
- Author(s)
  根来宏光
- Organizer
  山形臨床泌尿器科懇話会2018.1.10
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] Abyss of Nocturia －looking into the depth from circadian rhythm2018
- Author(s)
  根来宏光
- Organizer
  131th WPI-IIISセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 膀胱における時計遺伝子発現と膀胱容量変動のメカニズム（講演）2018
- Author(s)
  根来宏光
- Organizer
  第５階時間疫学研究会2018.2.17
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 夜尿の既往があると夜間頻尿になりやすい：ながはまコホート研究から2018
- Author(s)
  根来宏光
- Organizer
  第25回日本時間生物学会学術大会2018/10/20-21 (10/21)
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 体内時計と排尿障害の関わり（講演）2017
- Author(s)
  根来宏光
- Organizer
  male LUTS治療戦略セミナー2017.7.14
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] The circadian rhythm coordinates the ATP release in the urothelium via the connexin43 hemichannel2017
- Author(s)
  Atsushi Sengiku, Hiromitsu Negoro, Takeshi Sano, Masakatsu Ueda, Jin Kono, Kyoto, Japan, Louis Liou, Cambridge, MA, Hitoshi Okamura, Osamu Ogawa
- Organizer
  AUA 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] Mechanically-induced ATP release had oscillations in correlation with the Cx43 expression in urothelial cells.2017
- Author(s)
  Atsushi Sengiku, Hiromitsu Negoro, Masakatsu Ueda, Jin Kono, Takeshi Sano, Louis S. Liou, Hitoshi Okamura, Osamu Ogawa
- Organizer
  15th Urological Association of Asia Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 尿路上皮のコネキシン43は時計遺伝子の制御下に細胞間情報伝達機能を有する2017
- Author(s)
  千菊敦士、根来宏光、上田政克、河野仁、佐野剛視、國末純宏、辻花光次郎、岡村均、小川修
- Organizer
  第24回日本排尿機能学会
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 体内時計と排尿障害の関わり（講演）2017
- Author(s)
  根来宏光
- Organizer
  前立腺研究会 in 能登2017.7.21
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 日内排尿リズムを構成する膀胱時計2017
- Author(s)
  根来宏光
- Organizer
  第24回日本排尿機能学会（シンポジウム）2017.9.29
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 体内時計と夜間頻尿とタダラフィル2017
- Author(s)
  根来宏光
- Organizer
  第18回神戸地区泌尿器科カンファレンス
- Place of Presentation
  ホテルオークラ　京都
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 過活動膀胱の成因から治療まで-抗コリン薬の役割‐(講演)2017
- Author(s)
  根来宏光
- Organizer
  舞鶴医師会　学術講演会2017.4.20
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] Circadian rhythm in urothelium coordinates its ATP release via connexin43 hemichannel2017
- Author(s)
  Atsushi Sengiku, Hiromitsu Negoro, Jin Kono, Masakatsu Ueda, Takeshi Sano, Sumihiro Kunisue, Kojiro Tsujihana, Hitoshi Okamura, Osamu Ogawa
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 日内排尿リズムを司る膀胱時計2017
- Author(s)
  根来宏光
- Organizer
  第87回日本衛生学会学術総会
- Place of Presentation
  フェニックス・シーガイア・リゾート
- Year and Date
  2017-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 体内時計と排尿障害の関わり（講演）2017
- Author(s)
  根来宏光
- Organizer
  2017年石川県泌尿器科医会2017.6.22
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 概日時計と日内排尿リズム2016
- Author(s)
  根来宏光
- Organizer
  第11回Urology Study
- Place of Presentation
  ソラリア西鉄ホテル
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 体内時計と膀胱機能2016
- Author(s)
  根来宏光
- Organizer
  第72回ＮＧＢ研究会
- Place of Presentation
  日本新薬大阪営業所
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 体内時計と膀胱機能2016
- Author(s)
  根来宏光
- Organizer
  第104回泌尿器科学会総会
- Place of Presentation
  仙台国際センター
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 概日時計はLUTSに関与するのか？-そのメカニズムから治療を考える-2016
- Author(s)
  根来宏光
- Organizer
  第4回排尿イノベーションミーティングinさいたま
- Place of Presentation
  ラフォーレ清水園
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] ギャップジャンクションファミリーの膀胱での役割2015
- Author(s)
  根来宏光, 千菊敦士, Sylvia. O Suadicani, 小川修
- Organizer
  BMB2015ギャップジャンクションワークショップ
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] 概日時計と夜間頻尿2015
- Author(s)
  根来宏光　兼松明弘　小川修
- Organizer
  第30回日本睡眠学会（シンポジウム　睡眠障害と夜間頻尿の密接な関係)
- Place of Presentation
  宇都宮
- Year and Date
  2015-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] ギャップ結合ファミリーの尿路上皮における役割2015
- Author(s)
  根来宏光, 千菊敦士, Sylvia. O Suadicani, 小川修
- Organizer
  第22回日本排尿機能学会ワークショップ
- Place of Presentation
  札幌
- Year and Date
  2015-09-09
- Invited
- Data Source
  KAKENHI-PROJECT-15H05682
[Presentation] Coordination of day-night changes in urination by the circadian clock2014
- Author(s)
  根来宏光
- Organizer
  筑波グローバルサイエンス　シンポジウム
- Place of Presentation
  筑波大学
- Year and Date
  2014-09-28
- Invited
- Data Source
  KAKENHI-PROJECT-25893100
[Presentation] 尿路上皮とコネキシンの時間生物学
- Author(s)
  根来宏光
- Organizer
  第102回日本泌尿器科学会総会　ヤングリサーチグラント報告
- Place of Presentation
  神戸国際会議場
- Year and Date
  2014-04-23 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-25893100
[Presentation] 未来につながる排尿基礎研究
- Author(s)
  根来宏光
- Organizer
  第21回排尿機能学会　シンポジウム
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-09-17 – 2014-09-20
- Invited
- Data Source
  KAKENHI-PROJECT-25893100
[Presentation] Pannexin 1 channels participate in urothelial ATP release and signaling
- Author(s)
  根来宏光
- Organizer
  International Continence Society 2014
- Place of Presentation
  Rio de Janeiro, Brasil
- Year and Date
  2014-10-20 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25893100
[Presentation] 排尿を司る体内時計
- Author(s)
  根来宏光
- Organizer
  第102回日本泌尿器科学会総会　教育講演
- Place of Presentation
  神戸国際会議場
- Year and Date
  2014-04-23 – 2014-04-27
- Invited
- Data Source
  KAKENHI-PROJECT-25893100

1. 高岡栄一郎 (50625340)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. Ogawa Osamu (90260611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 神波大己 (20402836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 西山博之 (20324642)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 神鳥周也 (50707825)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 井上高光 (60375243)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 南雲義之 (00899122)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Yamasaki Toshinari (00607749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ITO Haruki (10817448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. Kawai Koji (90272195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OBAYASHI KENJI (30596656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 井上貴博 (80511881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 松井喜之 (00582107)

# of Collaborated Projects: 1 results

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14. 寺田直樹 (60636637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 後藤崇之 (90806605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 奥野博 (90263079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 坂根直樹 (40335443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 星昭夫 (90453711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 佐伯圭吾 (60364056)

# of Collaborated Projects: 1 results

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20. 山上優紀 (90823956)

# of Collaborated Projects: 1 results

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21. 吉川匡宣 (20632764)

# of Collaborated Projects: 1 results

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22. 小島崇宏 (40626892)

# of Collaborated Projects: 1 results

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23. 礒田博子 (00375429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 佐々木一憲 (60709715)

# of Collaborated Projects: 1 results

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25. 松本孔貴 (70510395)

# of Collaborated Projects: 1 results

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26. 黒部匡広 (30735949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 河原貴史 (50758919)

# of Collaborated Projects: 1 results

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28. 坂田麻実子 (80451805)

# of Collaborated Projects: 1 results

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29. 木村健一 (50633153)

# of Collaborated Projects: 1 results

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30. 田原康玄

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
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# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
32. 中山健夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 土居雅夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Negoro Hiromitsu 根来 宏光

NEGORO Hiromitsu 根来 宏光

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A Novel Therapeutic Approach for Nocturia Using a Model of Bladder Diurnal Rhythm Disruption by the Circadian ClockPrincipal Investigator

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Elucidation of the mechanism of reduction of bladder injury caused by radiotherapy and chronobiological approach to the development of new preventive methods.Principal Investigator

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Investigation into the mechanism of lower urinary tract dysfunction due to sleep disorder focusing on bladder clockPrincipal Investigator

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A chronobiological approach to elucidate nocturia focusing on the urotheliumPrincipal Investigator

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Diurnal change of urothelial function focusing on the hemichannel of connexin43Principal Investigator

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Negoro Hiromitsu 根来宏光

NEGORO Hiromitsu 根来宏光

[Book] 適正使用のための臨床時間薬理学生体リズムと薬物治療効果2022

[Journal Article] 特集朝まで待てない! 夜間頻尿完全マスター〈夜間頻尿の疫学と病態〉サーカディアンリズムと夜間頻尿2021