HAN SONG-IEE 韓松伊

… Alternative Names

HAN SONGIEE 韓松伊

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Researcher Number	80729541
Other IDs
Affiliation (Current)	2025: 筑波大学, 生存ダイナミクス研究センター, 研究員
Affiliation (based on the past Project Information) *help	2018 – 2021: 筑波大学, 国際統合睡眠医科学研究機構, 研究員 2014 – 2018: 筑波大学, 医学医療系, 研究員
Review Section/Research Field	Principal Investigator Applied health science / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
Keywords	Principal Investigator プロテアーゼ / SREBP-1 / lipid-sensing / 脂肪酸 / protease / 脂質代謝 / エネルギー代謝 / 転写因子複合体 / CREBH Except Principal Investigator オルガネラリピッドコード … More / 脂肪酸伸長酵素 / 脂質代謝 / 脂肪毒性 / ライブセルイメージング / 酵素 / リピドミクス / 転写因子 / オルガネラ / 脂肪酸 / 脂質 / ミトコンドリア / 小胞体 / 多価不飽和脂肪酸 Less

Elucidation of the molecular mechanism of lipid-sensing by the novel SREBP-1 protease R4Principal Investigator
- Principal Investigator
  
  Han Song-iee
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Tsukuba
Molecular mechanism of organella homeostasis regulated by quantity and quality of lipids
- Principal Investigator
  
  SHIMANO HITOSHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  University of Tsukuba
Analysis of SREBP-1 activation and lipid metabolism by novel proteasePrincipal Investigator
- Principal Investigator
  
  Han Song-Iee
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
Transcription factor complex formation and gene expression control in energy metabolismPrincipal Investigator
- Principal Investigator
  
  HAN SONGIEE
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba

All 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice2022
- Author(s)
  Okajima Yuka、Matsuzaka Takashi、Miyazaki Shun、Motomura Kaori、Ohno Hiroshi、Sharma Rahul、Shimura Takuya、Istiqamah Nurani、Han Song-iee、Mizunoe Yuhei、Osaki Yoshinori、Iwasaki Hitoshi、Yatoh Shigeru、Suzuki Hiroaki、Sone Hirohito、Miyamoto Takafumi、Aita Yuichi、Takeuchi Yoshinori、Sekiya Motohiro、Shimano Hitoshi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  
  Volume: 1868 Issue: 4 Pages: 166339-166339
- DOI
  10.1016/j.bbadis.2022.166339
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-22K11851, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-23K23562
[Journal Article] Association between use of Qingfei Paidu Tang and mortality in hospitalized patients with COVID-19: A national retrospective registry study2021
- Author(s)
  Zhang Lihua、Zheng Xin、Bai Xueke、Wang Qing、Chen Bowang、Wang Haibo、Lu Jiapeng、Hu Shuang、Zhang Xiaoyan、Zhang Haibo、Liu Jiamin、Shi Ying、Zhou Zhiye、Gan Lanxia、Li Xi、Li Jing
- Journal Title
  
  Phytomedicine
  
  Volume: 85 Pages: 153531-153531
- DOI
  10.1016/j.phymed.2021.153531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04051
[Journal Article] Protocol for rapid manipulation of mitochondrial morphology in living cells using inducible counter mitochondrial morphology (iCMM)2021
- Author(s)
  Miyamoto Takafumi、Han Song-Iee、Shimano Hitoshi
- Journal Title
  
  STAR Protocols
  
  Volume: 2 Issue: 3 Pages: 100721-100721
- DOI
  10.1016/j.xpro.2021.100721
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21K19064
[Journal Article] Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition2021
- Author(s)
  Nakagawa Yoshimi、Wang Yunong、Han Song-iee、Okuda Kanako、Oishi Asayo、Yagishita Yuka、Kumagai Kae、Ohno Hiroshi、Osaki Yoshinori、Mizunoe Yuhei、Araki Masaya、Murayama Yuki、Iwasaki Hitoshi、Konishi Morichika、Itoh Nobuyuki、Matsuzaka Takashi、Sone Hirohito、Yamada Nobuhiro、Shimano Hitoshi
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 11 Issue: 4 Pages: 949-971
- DOI
  10.1016/j.jcmgh.2020.11.004
- NAID
  120006939158
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K11737, KAKENHI-PROJECT-20K21611, KAKENHI-PROJECT-20K21643, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-20K17505, KAKENHI-PROJECT-18KT0065, KAKENHI-PROJECT-21H04861
[Journal Article] Starvation‐induced transcription factor CREBH negatively governs body growth by controlling GH signaling2021
- Author(s)
  Nakagawa Yoshimi、Kumagai Kae、Han Song‐iee、Mizunoe Yuhei、Araki Masaya、Mizuno Seiya、Ohno Hiroshi、Matsuo Kazuya、Yamada Yasunari、Kim Jun‐dal、Miyamoto Takafumi、Sekiya Motohiro、Konishi Morichika、Itoh Nobuyuki、Matsuzaka Takashi、Takahashi Satoru、Sone Hirohito、Shimano Hitoshi
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 6 Pages: 21663-21663
- DOI
  10.1096/fj.202002784rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05429, KAKENHI-PROJECT-19K07095, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21J11045, KAKENHI-PROJECT-21K19064
[Journal Article] CREBH Systemically Regulates Lipid Metabolism by Modulating and Integrating Cellular Functions2021
- Author(s)
  Nakagawa Yoshimi、Araki Masaya、Han Song-iee、Mizunoe Yuhei、Shimano Hitoshi
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 9 Pages: 3204-3204
- DOI
  10.3390/nu13093204
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21J11045
[Journal Article] Rapid manipulation of mitochondrial morphology in a living cell with iCMM2021
- Author(s)
  Miyamoto Takafumi、Uosaki Hideki、Mizunoe Yuhei、Han Song-Iee、Goto Satoi、Yamanaka Daisuke、Masuda Masato、Yoneyama Yosuke、Nakamura Hideki、Hattori Naoko、Takeuchi Yoshinori、Ohno Hiroshi、Sekiya Motohiro、Matsuzaka Takashi、Hakuno Fumihiko、Takahashi Shin-Ichiro、Yahagi Naoya、Ito Koichi、Shimano Hitoshi
- Journal Title
  
  Cell Reports Methods
  
  Volume: 1 Issue: 4 Pages: 100052-100052
- DOI
  10.1016/j.crmeth.2021.100052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K16536, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-19KK0219, KAKENHI-PROJECT-23K23562
[Journal Article] CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms2020
- Author(s)
  Satoh Aoi、Han Song-iee、Araki Masaya、Nakagawa Yoshimi、Ohno Hiroshi、Mizunoe Yuhei、Kumagai Kae、Murayama Yuki、Osaki Yoshinori、Iwasaki Hitoshi、Sekiya Motohiro、Konishi Morichika、Itoh Nobuyuki、Matsuzaka Takashi、Sone Hirohito、Shimano Hitoshi
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 3 Pages: 100930-100930
- DOI
  10.1016/j.isci.2020.100930
- NAID
  120006891020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07095, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-19H00449, KAKENHI-PROJECT-18K19724, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K11737, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-18KT0065
[Journal Article] Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl‐Chain Length and Hepatic Insulin Sensitivity in Mice2020
- Author(s)
  Matsuzaka T、Kuba M、Koyasu S、Yamamoto Y、Motomura K、Arulmozhiraja S、Ohno H、Sharma R、Shimura T、Okajima Y、Han SI、Aita Y、Mizunoe Y、Osaki Y、Iwasaki H、Yatoh S、Suzuki H、Sone H、Takeuchi Y、Yahagi N、Miyamoto T、Sekiya M、Nakagawa Y、Ema M、Takahashi S、Tokiwa H、Shimano H
- Journal Title
  
  Hepatology
  
  Volume: 71 Issue: 5 Pages: 1609-1625
- DOI
  10.1002/hep.30953
- NAID
  120007132717
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20175, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-18K19724, KAKENHI-PROJECT-17H05060, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-20K21611, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-18K06206
[Journal Article] Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis.2019
- Author(s)
  Shichino S, Ueha S, Hashimoto S, Otsuji M, Abe J, Tsukui T, Deshimaru S, Nakajima T, Kosugi-Kanaya M, Shand FH, Inagaki Y, Shimano H, Matsushima K.
- Journal Title
  
  JCI Insight.
  
  Volume: 4(1) Issue: 1 Pages: 122163-122163
- DOI
  10.1172/jci.insight.122163
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17K19546, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392
[Journal Article] Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism2019
- Author(s)
  Sharma Rahu, Takafumi Miyamoto, et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 5169-5169
- DOI
  10.1038/s41598-019-41631-1
- NAID
  120007133465
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06206, KAKENHI-PROJECT-18K19724, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-17H05060
[Journal Article] Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood2018
- Author(s)
  X Yuan, K Tsujimoto, K Hashimoto, K Kawahori, N Hanzawa, M Hamaguchi, T Seki, M Nawa, T Ehara, Y Kitamura, I Hatada, M Konishi, N Itoh, Y Nakagawa, H Shimano, T Takai-Igarashi, Y Kamei, Y Ogawa.
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 636-636
- DOI
  10.1038/s41467-018-03038-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00295, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K01840, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16H05331, KAKENHI-PROJECT-18K11420, KAKENHI-PROJECT-18K18461, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-16H04926, KAKENHI-PROJECT-17H06652
[Journal Article] Elovl6 regulates mechanical damage-induced keratinocyte death and skin inflammation.2018
- Author(s)
  Nakamura Y, Matsuzaka T, Tahara-Hanaoka S, Shibuya K, Shimano H, Nakahashi-Oda C, Shibuya A.
- Journal Title
  
  Cell Death Dis.
  
  Volume: 9(12) Issue: 12 Pages: 1181-1181
- DOI
  10.1038/s41419-018-1226-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H05022, KAKENHI-PROJECT-16H06387, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H05169, KAKENHI-PROJECT-17H04362, KAKENHI-PROJECT-18H03189, KAKENHI-PUBLICLY-17H05495, KAKENHI-PROJECT-16H05350, KAKENHI-PROJECT-17K19541
[Journal Article] Molecular association model of PPARα and its new specific and efficient ligand, pemafibrate: Structural basis for SPPARMα2018
- Author(s)
  Yamamoto Yuta、Takei Kenta、Arulmozhiraja Sundaram、Sladek Vladimir、Matsuo Naoya、Han Song-iee、Matsuzaka Takashi、Sekiya Motohiro、Tokiwa Takaki、Shoji Mitsuo、Shigeta Yasuteru、Nakagawa Yoshimi、Tokiwa Hiroaki、Shimano Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 499 Issue: 2 Pages: 239-245
- DOI
  10.1016/j.bbrc.2018.03.135
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0010, KAKENHI-PROJECT-16H03253, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16K01811
[Journal Article] Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance.2018
- Author(s)
  Ohno H, Matsuzaka T, Tang N, Sharma R, Motomura K, Shimura T, Satoh A, Han SI, Takeuchi Y, Aita Y, Iwasaki H, Yatoh S, Suzuki H, Sekiya M, Nakagawa Y, Sone H, Yahagi N, Yamada N, Higami Y, Shimano H.
- Journal Title
  
  Endocrinology.
  
  Volume: 159(6) Issue: 6 Pages: 2308-2323
- DOI
  10.1210/en.2017-03179
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-17H05060
[Journal Article] The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice2018
- Author(s)
  Araki Masaya、Nakagawa Yoshimi、Oishi Asayo、Han Song-iee、Wang Yunong、Kumagai Kae、Ohno Hiroshi、Mizunoe Yuhei、Iwasaki Hitoshi、Sekiya Motohiro、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 7 Pages: 2148-2148
- DOI
  10.3390/ijms19072148
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811
[Journal Article] The selective PPARα modulator K-877 efficiently activates the PPARα pathway and improves lipid metabolism in mice2017
- Author(s)
  Takei K, Han SI, Murayama Y, Satoh A, Oikawa F, Ohno H, Osaki Y, Matsuzaka T, Sekiya M, Iwasaki H, Yatoh S, Yahagi N, Suzuki H, Yamada N, Nakagawa Y, Shimano H.
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press Issue: 4 Pages: 446-452
- DOI
  10.1111/jdi.12621
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K09738, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16K13040
[Journal Article] Elovl6 Deficiency Improves Glycemic Control in Diabetic db / db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity2017
- Author(s)
  Zhao Hui、Matsuzaka Takashi、Nakano Yuta、Motomura Kaori、Tang Nie、Yokoo Tomotaka、Okajima Yuka、Han Song-iee、Takeuchi Yoshinori、Aita Yuichi、Iwasaki Hitoshi、Yatoh Shigeru、Suzuki Hiroaki、Sekiya Motohiro、Yahagi Naoya、Nakagawa Yoshimi、Sone Hirohito、Yamada Nobuhiro、Shimano Hitoshi
- Journal Title
  
  Diabetes
  
  Volume: 66 Issue: 7 Pages: 1833-1846
- DOI
  10.2337/db16-1277
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K09738, KAKENHI-PROJECT-17K13217, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-17H05060
[Journal Article] Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice.2017
- Author(s)
  Takei K, Nakagawa Y, Wang Y, Han SI, Satoh A, Sekiya M, Matsuzaka T, Shimano H.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 印刷中 Issue: 4 Pages: 214-222
- DOI
  10.1016/j.jphs.2017.02.003
- NAID
  120007128987
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-16H03253
[Journal Article] Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice.2016
- Author(s)
  Suzuki-Kemuriyama N, Matsuzaka T, Kuba M, Ohno H, Han SI, Takeuchi Y, Isaka M, Kobayashi K, Iwasaki H, Yatoh S, Suzuki H, Miyajima K, Nakae D, Yahagi N, Nakagawa Y, Sone H, Yamada N, Shimano H.
- Journal Title
  
  PLoS One.
  
  Volume: 11(6) Issue: 6 Pages: e0157580-e0157580
- DOI
  10.1371/journal.pone.0157580
- NAID
  120007135350
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K13040
[Journal Article] Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.2016
- Author(s)
  Kikuchi T, Orihara K, Oikawa F, Han SI, Kuba M, Okuda K, Satoh A, Osaki Y, Takeuchi Y, Aita Y, Matsuzaka T, Iwasaki H, Yatoh S, Sekiya M, Yahagi N, Suzuki H, Sone H, Nakagawa Y, Yamada N, Shimano H.
- Journal Title
  
  Mol Metab.
  
  Volume: 5 Pages: 1092-1102
- NAID
  120007129266
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811
[Journal Article] Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system.2016
- Author(s)
  Nakagawa Y, Oikawa F, Ohno H, Yagishita Y, Satoh A, Osaki Y, Takei K, Kikuchi T, Song-iee H, Mizuno S. Matsuzaka T, Iwasaki H, Kobayashi K, Yatoh S, Yahagi N, Suzuki H, Sone H, Takahashi S, Yamada N, Shimano H.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 27857-27857
- DOI
  10.1038/srep27857
- NAID
  120007135376
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-26500001, KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-16H06276
[Journal Article] Phosphorylation of MafA enhances interaction with Beta2/NeuroD1.2016
- Author(s)
  Han, S.-i, Y. Tsunekage, K. Kataoka
- Journal Title
  
  Acta Diabetologica
  
  Volume: - Issue: 4 Pages: 651-660
- DOI
  10.1007/s00592-016-0853-1
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461353, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K09763
[Journal Article] CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.2016
- Author(s)
  Nakagawa Y, Satoh A, Tezuka H, Han SI, Takei K, Iwasaki H, Yatoh S, Yahagi N, Suzuki H, Iwasaki Y, Sone H, Matsuzaka T, Yamada N, Shimano H.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 39182-39182
- DOI
  10.1038/srep39182
- NAID
  120007135285
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-15K09436, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K13040
[Journal Article] Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a2015
- Author(s)
  Kuba M, Matsuzaka T, Matsumori R, Saito R, Kaga N, Taka H, Ikehata K, Okada N,
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 17604-17604
- DOI
  10.1038/srep17604
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-26882008, KAKENHI-PROJECT-25430140, KAKENHI-PROJECT-26560392, KAKENHI-PROJECT-26800271, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-15H03092
[Journal Article] Gata3 cooperates with Gcm2 and MafB to activate parathyroid hormone gene expression by interacting with SP12015
- Author(s)
  SI. Han, Y. Tsunekage and K. Kataoka
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 409 Pages: 113-120
- DOI
  10.1016/j.mce.2015.04.018
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25111720, KAKENHI-PROJECT-25461353, KAKENHI-PROJECT-26882008
[Presentation] 腸肝転写因子CREBHはSREBPの活性を制御し、動脈硬化発症を抑制する(会議録)2020
- Author(s)
  中川嘉, 王雨農, 韓松伊, 水之江雄平, 荒木雅弥, 関谷元博, 松坂賢, 島野仁
- Organizer
  第 63 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 栄養環境センシングと制御(の分子基盤)　代謝産物センサー分子CtBP2を中心とした新しい代謝制御システムの同定2020
- Author(s)
  関谷元博, 戒能賢太, 馬洋, 松田高明, Gokhan Hotamisligil, 島野仁
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 新規プロテアーゼによるSREBP-1活性化制御機構の解明2020
- Author(s)
  韓松伊、中川嘉、宮本崇史、松坂賢、関谷元博、島野仁
- Organizer
  第43回日本分子生物学会年会（オンライン開催）
- Data Source
  KAKENHI-PROJECT-19K11713
[Presentation] 新規プロテアーゼによるSREBP-1活性化制御機構の解明2019
- Author(s)
  韓松伊、水之江雄平、中川嘉、関谷元博、松坂賢、島野仁
- Organizer
  第５６回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K11713
[Presentation] A metabolite sensor CtBP2 integrates metabolic flux to orchestrate glucose and lipid homeostasis in liver2019
- Author(s)
  Motohiro Sekiya, Hitoshi Shimano, Gokhan Hotamisligil
- Organizer
  60th International Conference on the Bioscience of Lipids
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 転写因子CREBHの未成熟型・成熟型による動脈硬化形成に対する二重支配の分子メカニズム2018
- Author(s)
  中川嘉、韓松伊、大石麻代、王雨農、関谷元博、松坂賢、島野仁
- Organizer
  第50回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 代謝産物センサーによる新しい脂質・糖代謝制御システムの解明と医療応用2018
- Author(s)
  関谷元博、菅澤威仁、馬　洋、戒能賢太、関根七海、Gokhan Hotamisligil、島野仁
- Organizer
  第50回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] MafAはリン酸化によりBeta2/NeuroDとの相互作用が亢進する2016
- Author(s)
  韓松伊、常陰幸乃、片岡浩介
- Organizer
  第39回日本分子生物学学会年会
- Place of Presentation
  パシフィコ横浜　神奈川県横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K01811
[Presentation] Gata3はSP1との相互作用を介してMafB及びGcm2と協調的に副甲状腺ホルモン遺伝子の発現を活性化する2015
- Author(s)
  韓松伊、常陰幸乃、片岡浩介
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26882008

1. 中川嘉 (80361351)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. SHIMANO HITOSHI (20251241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. 松坂賢 (70400679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. 関谷元博 (50420245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. 五十嵐貴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 常盤広明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 小西守周

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 片岡浩介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 金俊達

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 宮本崇史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 會田雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HAN SONG-IEE 韓 松伊

HAN SONGIEE 韓 松伊

Research Projects

Research Products

Co-Researchers

Elucidation of the molecular mechanism of lipid-sensing by the novel SREBP-1 protease R4Principal Investigator

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Molecular mechanism of organella homeostasis regulated by quantity and quality of lipids

Principal Investigator

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Review Section

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Analysis of SREBP-1 activation and lipid metabolism by novel proteasePrincipal Investigator

Principal Investigator

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Transcription factor complex formation and gene expression control in energy metabolismPrincipal Investigator

Principal Investigator

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[Journal Article] Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice2022

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[Journal Article] Association between use of Qingfei Paidu Tang and mortality in hospitalized patients with COVID-19: A national retrospective registry study2021

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[Journal Article] Protocol for rapid manipulation of mitochondrial morphology in living cells using inducible counter mitochondrial morphology (iCMM)2021

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[Journal Article] Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition2021

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NAID

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[Journal Article] Starvation‐induced transcription factor CREBH negatively governs body growth by controlling GH signaling2021

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[Journal Article] CREBH Systemically Regulates Lipid Metabolism by Modulating and Integrating Cellular Functions2021

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[Journal Article] Rapid manipulation of mitochondrial morphology in a living cell with iCMM2021

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[Journal Article] CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms2020

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DOI

NAID

Data Source

[Journal Article] Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl‐Chain Length and Hepatic Insulin Sensitivity in Mice2020

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DOI

NAID

Data Source

[Journal Article] Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis.2019

Author(s)

Journal Title

HAN SONG-IEE 韓松伊

HAN SONGIEE 韓松伊