Ota Wataru 太田航

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OTA Wataru 太田航

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Researcher Number	80866541
Other IDs
Affiliation (Current)	2026: 横浜市立大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 横浜市立大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related Except Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
Keywords	Principal Investigator リバーストランスレーショナル研究 / AMPA 受容体 / うつ / 躁 / 双極症 / 精神神経科学 / 動物行動生理学 / 躁状態 / 腹側被蓋野 (VTA) / 深部小脳核 (DCN) … More / PET トレーサー / 双極性障害 / 薬理遺伝学（DREADD） / 行動テスト / マウス / 小脳 / PET イメージング / 双極症（双極性障害） … More Except Principal Investigator 睡眠 / 時間栄養学 / 体内時計 / イメージング / 老化 / 概日時計 Less

リバーストランスレーショナル神経活動操作による双極症の病態メカニズムの解明Principal Investigator
- Principal Investigator
  
  太田航
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Yokohama City University
Effects of AMPA receptor levels in the brain on bipolar disorder, and its neural basisPrincipal Investigator
- Principal Investigator
  
  OTA Wataru
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Yokohama City University
Mechanisms underlying aging and disease related circadian dysfunctions by in vivo Miniscope
- Principal Investigator
  
  Tahara Yu
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Hiroshima University
  Waseda University

All 2025 2024 2023 2022 2021

All Journal Article Presentation Patent

[Journal Article] Edonerpic maleate enhances functional recovery from spinal cord injury with cortical reorganization in non-human primates2025
- Author(s)
  Uramaru Koichi、Abe Hiroki、Nakajima Waki、Ota Wataru、Suzuki Michiaki、Yokoyama Osamu、Yamamoto Tetsuya、Nishimura Yukio、Takahashi Takuya
- Journal Title
  
  Brain Communications
  
  Volume: 7 Issue: 2 Pages: 1-13
- DOI
  10.1093/braincomms/fcaf036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-20H05914, KAKENHI-PROJECT-21K11259, KAKENHI-PROJECT-21K15748, KAKENHI-PROJECT-20KK0229, KAKENHI-PROJECT-23K10432
[Journal Article] Synthesis and preclinical testing of a selective beta-subtype agonist of thyroid hormone receptor ZTA-2612024
- Author(s)
  Nambo M, Nishiwaki-Ohkawa T, Ito A, Ariki ZT, Ito Y, Kato Y, Yar M, Yim JCH, Kim E, Sharkey E, Kano K, Mishiro-Sato E, Okimura K, Maruyama M, Ota W, Furukawa Y, Nakayama T, Kobayashi M, Horio F, Sato A, Crudden CM, Yoshimura T
- Journal Title
  
  Communications Medicine
  
  Volume: 4 Issue: 1 Pages: 152-152
- DOI
  10.1038/s43856-024-00574-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24H02303, KAKENHI-PROJECT-24H00058, KAKENHI-PROJECT-23K21120, KAKENHI-PROJECT-22K19152, KAKENHI-PROJECT-21K15748, KAKENHI-PROJECT-20KK0229, KAKENHI-PROJECT-24K21821
[Journal Article] Edonerpic maleate prevents epileptic seizure during recovery from brain damage by balancing excitatory and inhibitory inputs2024
- Author(s)
  Katsuno Yuki、Jitsuki Susumu、Ota Wataru、Yamanoue Tomomi、Abe Hiroki、Takahashi Takuya
- Journal Title
  
  Frontiers in Neural Circuits
  
  Volume: 18 Pages: 1492043-1492043
- DOI
  10.3389/fncir.2024.1492043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-20H05914, KAKENHI-PROJECT-21K15748, KAKENHI-PROJECT-20KK0229, KAKENHI-PROJECT-24K02781, KAKENHI-PROJECT-23K10432
[Journal Article] Menstrual variations of sleep?wake rhythms in healthy women2024
- Author(s)
  Namie Tomoko、Kotaka Tsugumi、Watanabe Kazuto、Takasu Nana N.、Nakamura Wataru、Nakamura Takahiro J.
- Journal Title
  
  Sleep and Biological Rhythms
  
  Volume: 23 Issue: 1 Pages: 5-12
- DOI
  10.1007/s41105-024-00543-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0229, KAKENHI-PROJECT-24K10029
[Journal Article] Age-Related Decline in the Central Circadian Clock2023
- Author(s)
  Miyazaki Shota、Nakamura Wataru、Nakamura Takahiro J.
- Journal Title
  
  Healthy Ageing and Longevity book series
  
  Volume: 18 Pages: 95-103
- DOI
  10.1007/978-3-031-22468-3_4
- NAID
  40021684778
- ISBN
  9783031224676, 9783031224683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0229
[Journal Article] Circadian clock regulates tear secretion in the lacrimal gland,2021
- Author(s)
  Vu CHV, Kawashima M, Nakamura W, Nakamura TJ, Tsubota K.
- Journal Title
  
  Exp Eye Res.
  
  Volume: 108524 Pages: 108524-108524
- DOI
  10.1016/j.exer.2021.108524
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04022, KAKENHI-PROJECT-19K06360, KAKENHI-PROJECT-19K10046, KAKENHI-PROJECT-20KK0229
[Journal Article] GABA from vasopressin neurons regulates the time at which suprachiasmatic nucleus molecular clocks enable circadian behavior2021
- Author(s)
  Maejima Takashi、Tsuno Yusuke、Miyazaki Shota、Tsuneoka Yousuke、Hasegawa Emi、Islam Md Tarikul、Enoki Ryosuke、Nakamura Takahiro J.、Mieda Michihiro
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 6 Pages: 1-18
- DOI
  10.1073/pnas.2010168118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07259, KAKENHI-PROJECT-20K21498, KAKENHI-PROJECT-17H04022, KAKENHI-PROJECT-19H03399, KAKENHI-PROJECT-20H03425, KAKENHI-PROJECT-17K08561, KAKENHI-PROJECT-18K06509, KAKENHI-PROJECT-18K06519, KAKENHI-PROJECT-19K06360, KAKENHI-PLANNED-20H05769, KAKENHI-PROJECT-20H05669, KAKENHI-ORGANIZER-15H05935, KAKENHI-WRAPUP-20H05615, KAKENHI-PROJECT-20KK0229
[Patent] てんかん治療及び／又は予防剤、並びにそれを含む医薬組成物2024
- Inventor(s)
  高橋琢哉、勝野友貴、阿部弘基、太田航、實木亨
- Industrial Property Rights Holder
  高橋琢哉、勝野友貴、阿部弘基、太田航、實木亨
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-202789
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] Identification of neural circuits responsible for manic-depressive mood swings in bipolar disorder2025
- Author(s)
  Wataru Ota, Tomomi Yamanoue, Takuya Takahashi
- Organizer
  APPW2025
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] Therapeutic effects of mood stabilizer (lithium) treatment in a mouse model of bipolar disorder with altered cerebellar synapses2024
- Author(s)
  Wataru Ota, Tomomi Yamanoue, Takuya Takahashi
- Organizer
  NEURO2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0229
[Presentation] Therapeutic effects of mood stabilizer (lithium) treatment in a mouse model of bipolar disorder with altered cerebellar synapses2024
- Author(s)
  Wataru Ota, Tomomi Yamanoue, Takuya Takahashi
- Organizer
  NEURO2024（第47回日本神経科学大会、第46回日本生物学的精神医学会年会、第67回日本神経化学会大会、第8回アジアオセアニア神経科学連合コングレス）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] Lithium treatment rescued mania-like behavior in a synaptically modified mouse model of bipolar disorder2024
- Author(s)
  Wataru Ota, Takuya Takahashi
- Organizer
  第 101 回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20KK0229
[Presentation] Identification of the diffusible output factor from the suprachiasmatic nucleus in mice.2024
- Author(s)
  Takahiro J. Nakamura, Shota Miyazaki, Kazuto Watanabe, Shuto Mizuta, Wataru Nakamura, Daisuke Ono
- Organizer
  SSBR2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0229
[Presentation] Reduced AMPA receptors in the cerebellum induces bipolar mania via the ventral tegmental area2024
- Author(s)
  Wataru Ota, Takuya Takahashi
- Organizer
  The 35th World Congress Collegium Internationale Neuro-Psychopharmacologicum (CINP 2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0229
[Presentation] Lithium treatment rescued mania-like behavior in a synaptically modified mouse model of bipolar disorder2024
- Author(s)
  Wataru Ota, Takuya Takahashi
- Organizer
  第 101 回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] Reduced AMPA receptors in the cerebellum induces bipolar mania via the ventral tegmental area2024
- Author(s)
  Wataru Ota, Takuya Takahashi
- Organizer
  CINP2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] マウスの深部小脳核（DCN）-中脳腹側被蓋野（VTA）経路の活性化は躁様行動を引き起こす2024
- Author(s)
  太田航
- Organizer
  学術変革領域研究 (A) 臨界期生物学 (iPlasticity) 若手研究者オンライン講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] Therapeutic effects of mood stabilizer (lithium) treatment in a mouse model of bipolar disorder with altered cerebellar synapses2024
- Author(s)
  Wataru Ota, Tomomi Yamanoue, Takuya Takahashi
- Organizer
  学術変革領域研究 (A) 臨界期生物学 (iPlasticity) 夏の領域班会議 2024
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] Increased activity time (α) and activity fragmentation in a novel bipolar disorder (manic state) mouse model using a reverse translational approach2023
- Author(s)
  Wataru Ota and Takuya Takahashi
- Organizer
  The 100th Anniversary Annual Meeting of The Physiological Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] Downregulation of AMPA receptors in the cerebellum induces manic state in bipolar disorder via activation of the ventral tegmental area (VTA)2023
- Author(s)
  Wataru Ota, Takuya Takahashi
- Organizer
  学術変革領域研究 (A) 臨界期生物学 (iPlasticity) 夏の領域班会議
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] Downregulation of AMPA receptors in the cerebellum induces manic state in bipolar disorder via activation of the ventral tegmental area (VTA)2023
- Author(s)
  Wataru Ota, Takuya Takahashi
- Organizer
  学術変革領域研究 (A) 臨界期生物学 (iPlasticity) 夏の領域班会議 2023
- Data Source
  KAKENHI-PROJECT-20KK0229
[Presentation] マウスの深部小脳核（DCN）-中脳腹側被蓋野（VTA）経路の活性化は躁様行動を引き起こす2023
- Author(s)
  太田航, 山ノ上友美, 高橋琢哉
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] マウスの深部小脳核（DCN）-中脳腹側被蓋野（VTA）経路の活性化は躁様行動を引き起こす2023
- Author(s)
  太田航, 山ノ上友美, 高橋琢哉
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20KK0229
[Presentation] 概日リズム変容を伴う新規双極性障害（躁状態）モデルマウス2023
- Author(s)
  太田航, 山ノ上友美, 佐野亜加根, 高橋琢哉
- Organizer
  日本睡眠学会第 45 回定期学術集会・第 30 回日本時間生物学会学術大会合同大会
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] 概日リズム変容を伴う新規双極性障害（躁状態）モデルマウス2023
- Author(s)
  太田航, 山ノ上友美, 佐野亜加根, 高橋琢哉
- Organizer
  日本睡眠学会第45回定期学術集会・第30回日本時間生物学会学術大会合同大会
- Data Source
  KAKENHI-PROJECT-20KK0229
[Presentation] A novel animal model of bipolar disorder using a reverse translational approach2022
- Author(s)
  Wataru Ota, Susumu Jitsuki, Tomomi Yamanoue, Tomoyuki Miyazaki, Waki Nakajima, Mai Hatano, Akane Sano, Hideaki Tani, Nobuhiro Nagai, Teruki Koizumi, Shinichiro Nakajima, Masaru Mimura, Hiroyuki Uchida, and Takuya Takahashi
- Organizer
  NEURO2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15748
[Presentation] Reduction of cerebellar AMPA receptors induces bipolar mania-like behavior in mice2021
- Author(s)
  Wataru Ota, Susumu Jitsuki, Tomomi Yamanoue, Tomoyuki Miyazaki, Waki Nakajima, Mai Hatano, Akane Sano, Hideaki Tani, Nobuhiro Nagai, Teruki Koizumi, Shinichiro Nakajima, Masaru Mimura, Hiroyuki Uchida and Takuya Takahashi
- Organizer
  The 44th Annual Meeting of the Japan Neuroscience Society / The 1st CJK International Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15748

1. Tahara Yu (80707399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 中村孝博 (00581985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 原口敦嗣 (80834671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 吉村崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 高橋琢哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 津野祐輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ota Wataru 太田 航

OTA Wataru 太田 航

Research Projects

Research Products

Co-Researchers

リバーストランスレーショナル神経活動操作による双極症の病態メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of AMPA receptor levels in the brain on bipolar disorder, and its neural basisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms underlying aging and disease related circadian dysfunctions by in vivo Miniscope

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Edonerpic maleate enhances functional recovery from spinal cord injury with cortical reorganization in non-human primates2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and preclinical testing of a selective beta-subtype agonist of thyroid hormone receptor ZTA-2612024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Edonerpic maleate prevents epileptic seizure during recovery from brain damage by balancing excitatory and inhibitory inputs2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Menstrual variations of sleep?wake rhythms in healthy women2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Age-Related Decline in the Central Circadian Clock2023

Author(s)

Journal Title

DOI

NAID

ISBN

Data Source

[Journal Article] Circadian clock regulates tear secretion in the lacrimal gland,2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GABA from vasopressin neurons regulates the time at which suprachiasmatic nucleus molecular clocks enable circadian behavior2021

Author(s)

Journal Title

DOI

Data Source

[Patent] てんかん治療及び／又は予防剤、並びにそれを含む医薬組成物2024

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] Identification of neural circuits responsible for manic-depressive mood swings in bipolar disorder2025

Author(s)

Organizer

Data Source

[Presentation] Therapeutic effects of mood stabilizer (lithium) treatment in a mouse model of bipolar disorder with altered cerebellar synapses2024

Author(s)

Organizer

Data Source

[Presentation] Therapeutic effects of mood stabilizer (lithium) treatment in a mouse model of bipolar disorder with altered cerebellar synapses2024

Author(s)

Organizer

Data Source

[Presentation] Lithium treatment rescued mania-like behavior in a synaptically modified mouse model of bipolar disorder2024

Ota Wataru 太田航

OTA Wataru 太田航