Hongo Hiroki 本郷博貴

Researcher Number	80908682
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / 0906:Surgery related to the biological and sensory functions and related fields Except Principal Investigator Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator モデル動物 / 脳海綿状血管奇形 / 血管奇形 / 遺伝子変異 / 細胞実験 / 脳血管奇形 / 個別化治療 / 動物モデル Except Principal Investigator long read sequencing / long read sequence … More / RNF213 / もやもや病 / タンパク質構造解析 / 分子標的治療 / モデル動物 / 血管内皮細胞 / 血管奇形 / knock-in mouse / endothelial dysfunction / somatic mutation / connexin 37 / hemichannel / venous malformation / orbital lesion / GJA4 Less

Molecular mechanisms underlying acute hemorrhage in cerebral cavernous malformationsPrincipal Investigator
- Principal Investigator
  
  本郷博貴
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
Elucidation of genetic factors of moyamoya disease and search for therapeutic targets using long read sequencing
- Principal Investigator
  
  宮脇哲
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
Novel animal model of cerebrovascular malformationsPrincipal Investigator
- Principal Investigator
  
  Hongo Hiroki
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
Analysis of the pathogenesis of cerebral cavernous malformations using patient-derived xenograftsPrincipal Investigator
- Principal Investigator
  
  Hongo Hiroki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0906:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Analysis of novel vascular malformation causative gene
- Principal Investigator
  
  Saito Nobuhito
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo

All 2025 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Current molecular understanding of central nervous system schwannomas2025
- Author(s)
  Tsuchiya Takahiro、Miyawaki Satoru、Teranishi Yu、Ohara Kenta、Hirano Yudai、Ogawa Shotaro、Torazawa Seiei、Sakai Yu、Hongo Hiroki、Ono Hideaki、Saito Nobuhito
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 13(1) Issue: 1 Pages: 24-24
- DOI
  10.1186/s40478-025-01937-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] Stroke Events and Risk Factors in Older Patients with Moyamoya Disease2024
- Author(s)
  Hirano Yudai、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Kiyofuji Satoshi、Torazawa Seiei、Koizumi Satoshi、Miyazawa Ryota、Saito Nobuhito
- Journal Title
  
  World Neurosurgery
  
  Volume: 187 Pages: e405-e413
- DOI
  10.1016/j.wneu.2024.04.098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] POLR2A Mutation is a Poor Prognostic Marker of Cerebellopontine Angle Meningioma2024
- Author(s)
  Okano Atsushi、Miyawaki Satoru、Teranishi Yu、Hongo Hiroki、Dofuku Shogo、Ohara Kenta、Sakai Yu、Shin Masahiro、Nakatomi Hirofumi、Saito Nobuhito
- Journal Title
  
  Neurosurgery
  
  Volume: 95(2) Issue: 2 Pages: 275-283
- DOI
  10.1227/neu.0000000000002873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03041, KAKENHI-PROJECT-23K08507
[Journal Article] Aneurysmal formation of periventricular anastomosis is associated with collateral development of Moyamoya disease and its rupture portends poor prognosis: detailed analysis by multivariate statistical and machine learning approaches2024
- Author(s)
  Sato Daisuke、Miyawaki Satoru、Torazawa Seiei、Imai Hideaki、Hongo Hiroki、Kiyofuji Satoshi、Koizumi Satoshi、Saito Nobuhito
- Journal Title
  
  Neurosurgical Review
  
  Volume: 47(1) Issue: 1 Pages: 856-856
- DOI
  10.1007/s10143-024-03097-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] Contralateral Ischemia Subsequent to Revascularization for Moyamoya Disease.2024
- Author(s)
  Sato D, Miyawaki S, Imai H, Hongo H, Kiyofuji S, Koizumi S, Saito N.
- Journal Title
  
  World Neurosurg.
  
  Volume: 183
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] <i>RNF213</i> p.Arg4810Lys (c.14429G&gt;A) is associated with extracranial arterial stenosis2024
- Author(s)
  Shimada D#, Miyawaki S#, Nakanishi K, Jono T, Maruoka H, Kawai T, Harada Y, Kono T, Komatsubara K, Nakauchi J, Matsumoto Y, Okada K, Dofuku S, Hongo H, Mitsui J, Teranishi Y, Ohara K, Ishigami D, Sakai Y, Kawano H, Noguchi A, Nakatomi H, Saito N, Hirano T, Shiokawa Y.
- Journal Title
  
  Brain Communications
  
  Volume: 7(1) Issue: 1
- DOI
  10.1093/braincomms/fcaf049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] Association of rare variants in RNF213 with severe progression of intracranial artery stenosis in quasi?moyamoya disease2024
- Author(s)
  Torazawa Seiei、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Ishigami Daiichiro、Shimizu Masahiro、Sakai Yu、Ogawa Shotaro、Kiyofuji Satoshi、Koizumi Satoshi、Komura Daisuke、Katoh Hiroto、Ono Hideaki、Nakatomi Hirofumi、Ishikawa Shumpei、Saito Nobuhito
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: 142(2) Pages: 1-10
- DOI
  10.3171/2024.6.jns24202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] RNF213 p.Arg4810Lys Variant Is Associated with Higher Stenosis Progression in Asymptomatic Intracranial Artery Stenosis2024
- Author(s)
  Dofuku Shogo、Miyawaki Satoru、Imai Hideaki、Shimizu Masahiro、Hongo Hiroki、Shinya Yuki、Ohara Kenta、Teranishi Yu、Ono Hideaki、Nakatomi Hirofumi、Teraoka Akira、Saito Nobuhito
- Journal Title
  
  Translational Stroke Research
  
  Volume: Online ahead of print. Issue: 4 Pages: 1293-1300
- DOI
  10.1007/s12975-024-01309-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] Association of Genetic Variants with Postoperative Donor Artery Development in Moyamoya Disease: RNF213 and Other Moyamoya Angiopathy-Related Gene Analysis2024
- Author(s)
  Torazawa Seiei、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Ono Hideaki、Ogawa Shotaro、Sakai Yu、Kiyofuji Satoshi、Koizumi Satoshi、Komura Daisuke、Katoh Hiroto、Ishikawa Shumpei、Saito Nobuhito
- Journal Title
  
  Translational Stroke Research
  
  Volume: 16 Issue: 3 Pages: 679-689
- DOI
  10.1007/s12975-024-01248-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] Genetic analysis of foramen magnum meningiomas reveals AKT1 mutations uncomplicated by TRAF7 mutations2024
- Author(s)
  Hirano Yudai、Miyawaki Satoru、Sakai Yu、Teranishi Yu、Okano Atsushi、Umekawa Motoyuki、Hongo Hiroki、Torazawa Seiei、Ogawa Shotaro、Komura Daisuke、Katoh Hiroto、Ikemura Masako、Ushiku Tetsuo、Ishikawa Shumpei、Saito Nobuhito
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 12(1) Issue: 1 Pages: 123-123
- DOI
  10.1186/s40478-024-01835-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041, KAKENHI-PROJECT-23K08495
[Journal Article] A bibliometric analysis of the 100 most-cited clinical articles in the research of intracranial artery stenosis and intracranial atherosclerosis2024
- Author(s)
  Hirano Yudai、Miyawaki Satoru、Sakaguchi Yusuke、Koizumi Satoshi、Hongo Hiroki、Saito Nobuhito
- Journal Title
  
  Surgical Neurology International
  
  Volume: 15 Pages: 74-74
- DOI
  10.25259/sni_1030_2023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] Meningiomas in patients with neurofibromatosis type 2 predominantly comprise 'immunogenic subtype' tumours characterised by macrophage infiltration2023
- Author(s)
  Teranishi Y, Miyawaki S, Nakatochi M, Okano A, Ikemura M, Komura D, Katoh H, Mitsui J, Morishita S, Ushiku T, Ishikawa S, Nakatomi H, Saito N.
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 11(1) Issue: 1 Pages: 156-156
- DOI
  10.1186/s40478-023-01645-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H03041, KAKENHI-PROJECT-23K27709
[Journal Article] Bypass Surgery for Adult-Onset Hemorrhagic Moyamoya Disease: Analysis Classified by Site of Initial Bleeding.2023
- Author(s)
  Hirano Y, Miyawaki S, Imai H, Hongo H, Koizumi S, Yajima H, Torazawa S, Ishigami D, Kiyofuji S, Saito N.
- Journal Title
  
  World Neurosurg.
  
  Volume: 178
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] Hypertensive disorders of pregnancy in moyamoya disease: A single institution experience2023
- Author(s)
  Yajima Hirohisa、Miyawaki Satoru、Sayama Seisuke、Kumasawa Keiichi、Ikemura Masako、Imai Hideaki、Hongo Hiroki、Hirano Yudai、Ishigami Daiichiro、Torazawa Seiei、Kiyofuji Satoshi、Koizumi Satoshi、Saito Nobuhito
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 32 Issue: 11 Pages: 107377-107377
- DOI
  10.1016/j.jstrokecerebrovasdis.2023.107377
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16677, KAKENHI-PROJECT-21H03041, KAKENHI-PROJECT-23K27709
[Journal Article] Cerebrovascular Events During Treatment for Systemic Malignant Tumors in Patients with Moyamoya Disease2023
- Author(s)
  Ogawa Shotaro、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Umekawa Motoyuki、Kiyofuji Satoshi、Ishigami Daiichiro、Sakai Yu、Torazawa Seiei、Hirano Yudai、Koizumi Satoshi、Saito Nobuhito
- Journal Title
  
  World Neurosurgery
  
  Volume: 179 Pages: e314-e320
- DOI
  10.1016/j.wneu.2023.08.083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16677, KAKENHI-PROJECT-21H03041, KAKENHI-PROJECT-23K27709
[Journal Article] Clinical and Genetic Characteristics of Patients with Moyamoya Disease who Experienced Both Ischemic and Hemorrhagic Events2023
- Author(s)
  Hirano Yudai、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Teranishi Yu、Ishigami Daiichiro、Sakai Yu、Shimada Daisuke、Umekawa Motoyuki、Segawa Masafumi、Koizumi Satoshi、Ono Hideaki、Nakatomi Hirofumi、Saito Nobuhito
- Journal Title
  
  World Neurosurgery
  
  Volume: 172 Pages: e438-e446
- DOI
  10.1016/j.wneu.2023.01.047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16677, KAKENHI-PROJECT-21H03041
[Journal Article] RNF213 p.Arg4810Lys Wild Type is Associated with De Novo Hemorrhage in Asymptomatic Hemispheres with Moyamoya Disease2023
- Author(s)
  Torazawa Seiei、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Ishigami Daiichiro、Shimizu Masahiro、Ono Hideaki、Shinya Yuki、Sato Daisuke、Sakai Yu、Umekawa Motoyuki、Kiyofuji Satoshi、Shimada Daisuke、Koizumi Satoshi、Komura Daisuke、Katoh Hiroto、Ishikawa Shumpei、Nakatomi Hirofumi、Teraoka Akira、Saito Nobuhito
- Journal Title
  
  Translational Stroke Research
  
  Volume: 15(4) Issue: 4 Pages: 729-738
- DOI
  10.1007/s12975-023-01159-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041, KAKENHI-PROJECT-23K27709
[Journal Article] Bypass Surgery for Adult-Onset Hemorrhagic Moyamoya Disease: Analysis Classified by Site of Initial Bleeding2023
- Author(s)
  Hirano Yudai、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Koizumi Satoshi、Yajima Hirohisa、Torazawa Seiei、Ishigami Daiichiro、Kiyofuji Satoshi、Saito Nobuhito
- Journal Title
  
  World Neurosurgery
  
  Volume: 178 Pages: e585-e594
- DOI
  10.1016/j.wneu.2023.07.130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16677, KAKENHI-PROJECT-23K27709
[Journal Article] Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study2022
- Author(s)
  Dofuku S, Sonehara K, Miyawaki S, Sakaue S, Imai H, Shimizu M, Hongo H, Shinya Y, Ohara K, Teranishi Y, Okano A, Ono H, Nakatomi H, Teraoka A, Yamamoto K, Maeda Y, Nii T, Kishikawa T, Suzuki K, Hirata J, Takahashi M, Matsuda K, Kumanogoh A, Matsuda F, Okada Y, Saito N.
- Journal Title
  
  Transl Stroke Res.
  
  Volume: - Issue: 3 Pages: 322-333
- DOI
  10.1007/s12975-022-01049-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-22K16677
[Journal Article] NF2 Alteration/22q Loss Is Associated with Recurrence in WHO Grade 1 Sphenoid Wing Meningiomas2022
- Author(s)
  Sakai Y, Miyawaki S, Teranishi Y, Okano A, Ohara K, Hongo H, Ishigami D, Shimada D, Mitsui J, Nakatomi H, Saito N.
- Journal Title
  
  Cancers (Basel)
  
  Volume: 14(13):3183 Issue: 13 Pages: 3183-3183
- DOI
  10.3390/cancers14133183
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21H03041
[Journal Article] Genetics of brain arteriovenous malformations and cerebral cavernous malformations2022
- Author(s)
  Hongo Hiroki、Miyawaki Satoru、Teranishi Yu、Ishigami Daiichiro、Ohara Kenta、Sakai Yu、Shimada Daisuke、Umekawa Motoyuki、Koizumi Satoshi、Ono Hideaki、Nakatomi Hirofumi、Saito Nobuhito
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 3 Pages: 157-167
- DOI
  10.1038/s10038-022-01063-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16677, KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21K20985, KAKENHI-PROJECT-21H03041
[Journal Article] Symptomatic and Stenotic Developmental Venous Anomaly with Pontine Capillary Telangiectasia: A Case Report with Genetic Considerations2022
- Author(s)
  ISHIGAMI Daiichiro、KOIZUMI Satoshi、MIYAWAKI Satoru、HONGO Hiroki、TERANISHI Yu、MITSUI Jun、SAITO Nobuhito
- Journal Title
  
  NMC Case Report Journal
  
  Volume: 9 Issue: 0 Pages: 139-144
- DOI
  10.2176/jns-nmc.2022-0022
- ISSN
  2188-4226
- Year and Date
  2022-12-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16677, KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21K20985
[Journal Article] Clinical significance of NF2 alteration in grade I meningiomas revisited; prognostic impact integrated with extent of resection, tumour location, and Ki-67 index2022
- Author(s)
  Teranishi Y, Okano A, Miyawaki S, Ohara K, Ishigami D, Hongo H, Dofuku S, Takami H, Mitsui J, Ikemura M, Komura D, Katoh H, Ushiku T, Ishikawa S, Shin M, Nakatomi H, Saito N.
- Journal Title
  
  Acta Neuropathol Commun
  
  Volume: 10(1):76 Issue: 1 Pages: 76-76
- DOI
  10.1186/s40478-022-01377-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21H03041
[Journal Article] Early prediction of functional prognosis in neurofibromatosis type 2 patients based on genotype-phenotype correlation with targeted deep sequencing2022
- Author(s)
  Yu Teranishi、Satoru Miyawaki、Hirofumi Nakatomi、Kenta Ohara、Hiroki Hongo、Shogo Dofuku、Atsushi Okano、Shunsaku Takayanagi、Takahiro Ota、Jun Yoshimura、Wei Qu、Jun Mitsui、Shinichi Morishita、Shoji Tsuji、Nobuhito Saito
- Journal Title
  
  Scientific Reports
  
  Volume: 12(1) Issue: 1 Pages: 9543-9543
- DOI
  10.1038/s41598-022-13580-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21H03041
[Journal Article] Somatic GJA4 gain-of-function mutation in orbital cavernous venous malformations2022
- Author(s)
  Hongo Hiroki、Miyawaki Satoru、Teranishi Yu、Mitsui Jun、Katoh Hiroto、Komura Daisuke、Tsubota Kinya、Matsukawa Takashi、Watanabe Masakatsu、Kurita Masakazu、Yoshimura Jun、Dofuku Shogo、Ohara Kenta、Ishigami Daiichiro、Okano Atsushi、Kato Motoi、Hakuno Fumihiko、Takahashi Ayaka、Kunita Akiko、Ishiura Hiroyuki、et al.
- Journal Title
  
  Angiogenesis
  
  Volume: 26 Issue: 1 Pages: 37-52
- DOI
  10.1007/s10456-022-09846-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16677, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-20K07417, KAKENHI-PROJECT-20K07422, KAKENHI-PROJECT-21K20985, KAKENHI-PROJECT-21H03041
[Journal Article] Associations of pathological diagnosis and genetic abnormalities in meningiomas with the embryological origins of the meninges.2021
- Author(s)
  Okano A, Miyawaki S, Hongo H, Dofuku S, Teranishi Y, Mitsui J, Tanaka M, Shin M, Nakatomi H, Saito N.
- Journal Title
  
  Sci Rep.
  
  Volume: 11(1) Issue: 1 Pages: 6987-6987
- DOI
  10.1038/s41598-021-86298-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21H03041
[Journal Article] Differences in Clinical Features among Different Onset Patterns in Moyamoya Disease.2021
- Author(s)
  Hirano Y, Miyawaki S, Imai H, Hongo H, Teranishi Y, Dofuku S, Ishigami D, Ohara K, Koizumi S, Ono H, Nakatomi H, Saito N.
- Journal Title
  
  J Clin Med.
  
  Volume: 10(13) Issue: 13 Pages: 2815-2815
- DOI
  10.3390/jcm10132815
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] RNF213 p.Arg4810Lys Heterozygosity in Moyamoya Disease Indicates Early Onset and Bilateral Cerebrovascular Events.2021
- Author(s)
  Ishigami D, Miyawaki S, Imai H, Shimizu M, Hongo H, Dofuku S, Ohara K, Teranishi Y, Shimada D, Koizumi S, Ono H, Hirano Y, Segawa M, Nakatomi H, Saito N.
- Journal Title
  
  Transl Stroke Res.
  
  Volume: 13(3) Issue: 3 Pages: 410-419
- DOI
  10.1007/s12975-021-00956-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21H03041
[Presentation] 脳血管疾患の遺伝子解析研究の現況と課題（シンポジウム　招待講演）2024
- Author(s)
  宮脇哲　本郷博貴、齊藤延人
- Organizer
  日本脳神経外科学会第83回学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] Molecular pathogenesis of central nervous system vascular malformations2024
- Author(s)
  Hiroki Hongo, Satoru Miyawaki, Nobuhito Saito
- Organizer
  NSI-YNFCON 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K02555
[Presentation] Molecular pathogenesis of central nervous system vascular malformations. （国際学会）（招待講演）2024
- Author(s)
  Hiroki Hongo, Satoru Miyawaki, Nobuhito Saito.
- Organizer
  3rd Annual Meeting of The Young NeuroSurgeon's Forum of The Neurological Society of India. The Orchid Hotel in Pune
- Invited
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 脳・脊髄海綿状血管奇形の臨床経過におけるPIK3CA変異とMAP3K3変異の意義2024
- Author(s)
  本郷博貴, 宮脇哲, 髙井敬介, 小野秀明, 清水暢裕, 寺西裕, 清藤哲史, 小原健太, 石神大一郎, 酒井優, 虎澤誠英, 小川正太郎, 島田大輔, 中冨浩, 齊藤延.
- Organizer
  STROKE 2024
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 新規血管奇形原因遺伝子変異の探索: GJA4変異の同定と機能解析2023
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人.
- Organizer
  第8回血管生物医学会若手研究会
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] Contralateral ischemic events subsequent to revascularization surgery for moyamoya disease.2023
- Author(s)
  Satoru Miyawaki, Daisuke Sato, Hideaki Imai, Hiroki Hongo, Satoshi Kiyofuji, Satoshi Koizumi, Nobuhito Saito.
- Organizer
  16th Korea-Japan Joint Conference on Surgery for Cerebral Stroke
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27709
[Presentation] Genome-Wide association studyによる頭蓋内血管狭窄の遺伝的要因の探索2023
- Author(s)
  宮脇哲、堂福翔吾、曽根原究人、今井英明、清水暢裕、本郷博貴、新谷祐貴、小原健太、寺西裕、岡野淳、小野秀明、中冨浩文、寺岡暉、岡田随象、斉藤延人
- Organizer
  第66回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27709
[Presentation] 脳および眼窩内海綿状血管奇形の体細胞遺伝子変異解析2023
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人.
- Organizer
  第52回日本脳卒中の外科学会
- Data Source
  KAKENHI-PROJECT-22K16677
[Presentation] 脳・眼窩内血管奇形の遺伝子解析研究（シンポジウム）（招待講演）2023
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 清藤哲史, 三井純, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人.
- Organizer
  第81回日本脳神経外科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] RNF213 p.Arg4810Lys heterozygote is associated with early onset and bilateral cerebrovascular events in Moyamoya disase2023
- Author(s)
  Satoru Miyawaki, Daiichiro Ishigami, Hideaki Imai, Masahiro Shimizu, Hiroki Hongo, Shogo Dofuku, Kenta Ohara, Yu Teranishi, Daisuke Shimada, Satoshi Koizumi, Hideaki Ono, Yudai Hirano, Masafumi Segawa, Hirofumi Nakatomi, Nobuhito Saito.
- Organizer
  Human Genetics Asia 2023（HGA2023）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27709
[Presentation] 多発性脳海綿状血管奇形に対する生殖細胞系列遺伝子解析.2023
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 石神大一郎, 小原健太, 酒井優, 齊藤延人.
- Organizer
  第47回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 脳・眼窩内血管奇形の遺伝子解析研究2023
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 清藤哲史, 三井純, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人.
- Organizer
  第81回日本脳神経外科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16677
[Presentation] Identification of a somatic GJA4 mutation in orbital cavernous venous malformations2023
- Author(s)
  Hiroki Hongo, Satoru Miyawaki, Yu Teranishi, Shogo Dofuku, Kenta Ohara, Daiichiro Ishigami, Atsushi Okano, Jun Mitsui, Hiroto Katoh, Masakazu Kurita, Masakatsu Watanabe, Masahiro Shin, Hirofumi Nakatomi, Hiroshi Goto, Shumpei Ishikawa, Nobuhito Saito.
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] RNF213遺伝子全体の変異解析を通じたもやもや病の遺伝子型と臨床表現型との関連解析2023
- Author(s)
  宮脇哲、虎澤誠英、今井英明、清水暢裕、小野秀明、新谷祐貴、本郷博貴、石神大一郎、酒井優、梅川元之、清藤哲史、島田大輔、小泉聡、中冨浩文、寺岡暉、齊藤延人
- Organizer
  第66回日本脳循環代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27709
[Presentation] 脳および眼窩内海綿状血管奇形の体細胞遺伝子変異解析（シンポジウム）2023
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人.
- Organizer
  STROKE 2023
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] Epidemiology/etiology of cerebral cavernous malformations.2022
- Author(s)
  Hiroki Hongo, Satoru Miyawaki, Nobuhito Saito.
- Organizer
  10th European-Japanese Cerebrovascular Congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 眼窩内海綿状血管奇形関連遺伝子変異の同定2022
- Author(s)
  本郷博貴, 宮脇哲, 栗田昌和, 加藤基, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 岡崎睦, 齊藤延人
- Organizer
  第18回日本血管腫血管奇形学会学術集会
- Data Source
  KAKENHI-PROJECT-21K20985
[Presentation] 眼窩内海綿状血管奇形における新規関連遺伝子変異の同定2022
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-21K20985
[Presentation] 眼窩内海綿状血管奇形関連遺伝子変異の同定.2022
- Author(s)
  本郷博貴, 宮脇哲, 栗田昌和, 加藤基, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 岡崎睦, 齊藤延人.
- Organizer
  第18回日本血管腫血管奇形学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 眼窩内海綿状血管奇形における新規関連遺伝子変異の同定2022
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-22K16677
[Presentation] 眼窩内海綿状血管奇形関連遺伝子変異の同定2022
- Author(s)
  本郷博貴, 宮脇哲, 栗田昌和, 加藤基, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 岡崎睦, 齊藤延人
- Organizer
  第18回日本血管腫血管奇形学会学術集会
- Data Source
  KAKENHI-PROJECT-22K16677
[Presentation] 眼窩内海綿状血管奇形における新規関連遺伝子変異の同定.2022
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人.
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 多発性脳海綿状血管奇形に対する生殖細胞系列遺伝子解析（一般口演）2022
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 石神大一郎, 小原健太, 酒井優, 斉藤延人.
- Organizer
  第47回日本脳卒中学会学術集会　大阪国際会議場（ハイブリッド開催）
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] Epidemiology/etiology of cerebral cavernous malformations2022
- Author(s)
  Hiroki Hongo, Satoru Miyawaki, Nobuhito Saito
- Organizer
  10th European-Japanese Cerebrovascular Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20985
[Presentation] Epidemiology/etiology of cerebral cavernous malformations2022
- Author(s)
  Hiroki Hongo, Satoru Miyawaki, Nobuhito Saito
- Organizer
  10th European-Japanese Cerebrovascular Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16677
[Presentation] 脳海綿状血管奇形のgermline mutationとcopy number variationの解析（シンポジウム）2021
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 石神大一郎, 小原健太, 酒井優, 斉藤延人.
- Organizer
  第80回日本脳神経外科学会総会　パシフィコ横浜（WEB併催）
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 脳海綿状血管奇形におけるgermline mutationの解析（一般口演）2021
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 石神大一郎, 小原健太, 酒井優, 中冨浩文, 斉藤延人.
- Organizer
  第21回日本分子脳神経外科学会　WEB開催
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 脳海綿状血管奇形におけるgermline mutation解析（一般口演）2021
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 石神大一郎, 小原健太, 酒井優, 中冨浩文, 斉藤延人,
- Organizer
  第64回日本脳循環代謝学会学術集会　長良川国際会議場（ハイブリッド開催）
- Data Source
  KAKENHI-PROJECT-21H03041

1. Saito Nobuhito (60262002)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 宮脇哲 (70407914)

# of Collaborated Projects: 3 results

# of Collaborated Products: 39 results
3. 石川俊平 (50418638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
4. 三井純 (70579862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. 栗田昌和 (20424111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. 寺西裕 (50844635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
7. 小野秀明 (50771846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 岡田随象 (70727411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 森下真一 (90292854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. NAKATOMI Hirofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
11. ITOH Takehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 斎藤延人

# of Collaborated Projects: 0 results

# of Collaborated Products: 39 results
13. 齊藤祐子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 中杤昌弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 森宙史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hongo Hiroki 本郷 博貴

Research Projects

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Co-Researchers

Molecular mechanisms underlying acute hemorrhage in cerebral cavernous malformationsPrincipal Investigator

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Elucidation of genetic factors of moyamoya disease and search for therapeutic targets using long read sequencing

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Novel animal model of cerebrovascular malformationsPrincipal Investigator

Principal Investigator

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Analysis of the pathogenesis of cerebral cavernous malformations using patient-derived xenograftsPrincipal Investigator

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Analysis of novel vascular malformation causative gene

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[Journal Article] Current molecular understanding of central nervous system schwannomas2025

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[Journal Article] Stroke Events and Risk Factors in Older Patients with Moyamoya Disease2024

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[Journal Article] POLR2A Mutation is a Poor Prognostic Marker of Cerebellopontine Angle Meningioma2024

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[Journal Article] Aneurysmal formation of periventricular anastomosis is associated with collateral development of Moyamoya disease and its rupture portends poor prognosis: detailed analysis by multivariate statistical and machine learning approaches2024

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[Journal Article] Contralateral Ischemia Subsequent to Revascularization for Moyamoya Disease.2024

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[Journal Article] <i>RNF213</i> p.Arg4810Lys (c.14429G&amp;gt;A) is associated with extracranial arterial stenosis2024

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[Journal Article] Association of rare variants in RNF213 with severe progression of intracranial artery stenosis in quasi?moyamoya disease2024

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[Journal Article] RNF213 p.Arg4810Lys Variant Is Associated with Higher Stenosis Progression in Asymptomatic Intracranial Artery Stenosis2024

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[Journal Article] Association of Genetic Variants with Postoperative Donor Artery Development in Moyamoya Disease: RNF213 and Other Moyamoya Angiopathy-Related Gene Analysis2024

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[Journal Article] Genetic analysis of foramen magnum meningiomas reveals AKT1 mutations uncomplicated by TRAF7 mutations2024

Author(s)

Hongo Hiroki 本郷博貴

[Journal Article] <i>RNF213</i> p.Arg4810Lys (c.14429G>A) is associated with extracranial arterial stenosis2024