MURAI Masaru 村井勝

Researcher Number	90101956
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007: Keio University, School of Medicine, Professor Emiritus 1996 – 2006: Keio Univ.School of Med.Professor, 医学部, 教授 1999: 慶応義塾大学, 医学部, 教授 1995: Keio Univ., Dept.of Urology, Associate Professor, 医学部・泌尿器科, 助教授 1994 – 1995: 慶應義塾大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Urology / Urology Except Principal Investigator Urology / Urology / Human pathology
Keywords	Principal Investigator bcl-2 / 前立腺癌 / NF-κB / STAT3 / NFkappaB / アポトーシス / NFκB / 泌尿器系癌 / prostate cancer / 遺伝子治療 … More / PSA / cytokine / metastasis / apoptosis / urological malignancy / 殺細胞効果 / 膀胱癌 / IL-6 / 細胞周期 / 放射線治療 / 悪液質 / 転移 / angiogenesis / bone metastases / 血管内皮細胞 / レトロウイルスベクター / ヒト腫瘍血管新 / SCIDマウス / NOD / ヒト腫瘍血管新生 / VEGF / 血管新生 / 骨転移 / molecular targeting / urological malignancies / TRAIL / 腎細胞癌 / 分子標的 / gere therapy / Cytosine deminase / 5-fluorocytosine / プロモーター / lymphocyte subsets / immunosuppression / renal transplantation / 免疫抑制療法 / DST / リンパ球サブセット / 免疫抑制 / 腎移植 … More Except Principal Investigator 前立腺癌 / prostate cancer / SEREX / 腎細胞癌 / IL-6 / apoptosis / TNF / サイトカイン / 膀胱癌 / アポトーシス / VEGF / hypoxia inducible factor / DHMEQ / ビタミンE / 細胞周期 / アンドロゲン受容体 / Akt / AP-2 / EBP / C / NF-κB / LIF / HLA-A24 / CTL / diethylstilbestrol / bcl-2 / Renal cell carcinoma / cytokine / 細胞増殖 / interleukin 6 / gene therapy / 遺伝子治療 / SAGE / MAGE / Intra Cavernous Pressure / Cavernous Nerve / Erectile Dysfunction / 勃起不全モデル / 糖尿病性 / 陰茎海綿体内圧 / 海綿体神経 / 勃起不全 / chemotherapy / histone / vitamin / ヒストン / 抗癌剤 / ヒストン修飾 / ビタミン / vascular endothelial growth factor / renal cell carcinoma / hypoxia / VHL / HIF / 血管新生 / 低酸素 / Acute rejection / Ischemia-reperfusion injury / Transplantation / 急性拒絶反応 / 虚血再灌流障害 / 移植 / angiogenesis / angiotensin II / hormone-refractory / アンギオテンシンII 受容体 / アンギオテンシン / アンギオテンシンII受容体 / ホルモン抵抗性 / Vitamin E / Cell cycle / Androgen receptor / Prostate carcinoma / MAP kinase / EBP-β / MAPキナーゼ / cachexia / cell growth / ヌードマウス / 悪液質 / peptide / cancer targeting therapy / prostate specific membrane antigen / dendritic cell / immunotherapy / 前立腺癌特異的膜抗原 / ペプチド / 癌標的治療 / 前立腺特異的膜抗原 / 樹状細胞 / 免疫療法 / radiation / 放射線治療 / tissue-specific / targeting / suicide gene therapy / promotor / liposome / enhancer / 特異的プロモーター / ターゲティング / エンハンサー / プロモーター / 組織特異的 / 自殺遺伝子 / リポソーム / ターゲッティング / comparative genomic hybridization / multicentiicity / VHL tumor suppressor gene / CGH / 多発性 / VHL病腫瘍抑制遺伝子 / allopurinol / adherence / urothelium / calcium oxalate / 細胞障害 / 結晶付着 / アロプリノール / 付着 / 尿路上皮細胞 / 蓚酸カルシウム / Targetting / Mutant Virus / Viral therapy / Bladder Neoplasm / 変異ウイルス / ヘルペスウイルス / ウイルス治療 / 腫瘍特異的 / ヘルペスウィルス / ウィルス治療 / prognosis / crostate cancer / インターロイキン6 / 骨転移 / 予後 / IKB / adenovirus / NF κ B / cytokine-producing cancer cells / アデノウイルスベクター / 細胞死誘導 / IκB / サイトカイン産生腫瘍 / ANTIGEN OF RCC / 腎癌抗原 / CT antigen / TC抗原 / tumorspecific immunotherapy / nuclear factor kappa B / ogan preserving treatment / advanced urological cancers / レチノインサン / autocrine growth / 増殖因子 / 泌尿器科癌 / 殺細胞効果 / G-CSF / ビンブラスチン / メトトレキセート / 尿路上皮癌 / 増殖活性 / 進行尿路癌 / 腫瘍特異的免疫治療 / Apoptosis / 転写因子抑制 / 機能温存治療 / 進行性尿路癌 / Prognostic factor / genes, p53 / Polymerase chain reaction / Recurrence / Superficial tumor / bladder cancer / 突然変異 / 表在性癌 / p53 / 癌抑制遺伝子 / 細胞学的悪性度 / p53遺伝子 / 膀胱移行上皮癌 / 泌尿器科悪性腫瘍 / differentiation / bladder / tissue engineering / エストロゲンレセプター Less

Development of new chemotherapy for refractory prostate cancer
- Principal Investigator
  
  OHIGASHI Takashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Establishment of new treatment strategy for diabetic erectile dysfunction
- Principal Investigator
  
  KIKUCHI Eiji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Hypoxia responsiveness in renal cell carcinoma
- Principal Investigator
  
  OYA Mototsugu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  KEIO UNIVERSITY
Pathophysiological role of NF k B and the efficacy of a novel NF K B inhibitor in urological cancersPrincipal Investigator
- Principal Investigator
  
  MURAI Masaru
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Keio University
Gene therapy for hormone-refractory prostate cancer targeting androgen receptor
- Principal Investigator
  
  OHIGASHI Takashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Anti-tumor effects of angiotensin II type 1 antagonist in hormone-refractory prostate cancer.
- Principal Investigator
  
  MIYAJIMA Akira
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Anew strategy utilizing a novel NF-κB inhibitor for renal allograft rejection.
- Principal Investigator
  
  NAKAGAWA Ken
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Role of cytokine-inducible transcription factors in renal cell carcinoma
- Principal Investigator
  
  OYA Mototsugu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
骨髄間質細胞から膀胱組織の再生医療に関する研究
- Principal Investigator
  
  大東貴志
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Keio University
Prostate cancer specific cell-mediated immunotherapy utilizing dendritic cells pulsed with prostate-specific antigen
- Principal Investigator
  
  HORIGUCHI Yutaka
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  KEIO UNIVERSITY
Elucidation of pathophysiological significance of LIF and development of new treatment strategy in prostate cancer
- Principal Investigator
  
  NAKASHIMA Jun
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Establishment of gene therapy targeting bcl-2 and NF κB for urological malignanciesPrincipal Investigator
- Principal Investigator
  
  MURAI Masaru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Keio University
Establishment of a novel mouse model for studying prostate cancer metastasis to human bone and new therapeutic strategies.Principal Investigator
- Principal Investigator
  
  MURAI Masaru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  KEIO UNIVERSITY
Establishment of radiotherapy combined with antisense bcl-2 oligodeoxynucleotide in prostate cancer
- Principal Investigator
  
  MARUMO Ken, KIKUCHI Eiji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
THE ADHERENCE OF CALCIUM OXALATE CRYSTAL ON UROTHELIUM AND CYTOKINE PRODUCTION
- Principal Investigator
  
  NAKAJIMA Fumio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Genetic analysis of multiple sproradic renal call carcinoma
- Principal Investigator
  
  OYA Mototsugu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Targeting suicide gene therapy for prostate cancer utilizing HVJ-liposome
- Principal Investigator
  
  HORIGUCHI Yutaka
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
腎細胞癌におけるホルモン依存性増殖の解明と治療への応用
- Principal Investigator
  
  堀口明男
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Tumor Specific Gene Therapy Using Mutant Herpes Simplex Virus for Bladder Cancer
- Principal Investigator
  
  OHIGASHI Takashi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Identification of new tumor antigens using testis-specific proteins
- Principal Investigator
  
  FUJITA Tomonobu
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Keio University
IDENTIFICATION OF NEW ANTIGENS IN RENAL CELL CARCINOMA
- Principal Investigator
  
  SUZUKI Yuriko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Induction of apoptosis against cytokine-producing urological cancer
- Principal Investigator
  
  TACHIBANA Masaaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Pathophysiological role of IL-6 and IL-8 in the progression of prostate cancer and cachexia
- Principal Investigator
  
  NAKASHIMA Jun
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Targeting gene therapy for prostate cancer using prostate specific antigen (PSA)Principal Investigator
- Principal Investigator
  
  MURAI Masaru
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Urology
- Research Institution
  Keio University
Establish mentofthe minimally invasive treatments based on biological characteristics for advanceduro logical cancers.
- Principal Investigator
  
  TACHIBANA Masaaki
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Urology
- Research Institution
  Keio University
Effect of donor specific antigen on graft survivalPrincipal Investigator
- Principal Investigator
  
  MURAI Masaru
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
p53 gene mutation inrecurrent superficial bladder cancer
- Principal Investigator
  
  NAKAMURA Kaoru
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  School of Medicine, Keio University

All 2007 2006 2005 2004 2003 Other

All Journal Article

[Journal Article] Renal cancer cells lacking hypoxia inducible factor (HIF) 1-α expression maintain vascular endotheltal growth factor expression through HIF 22007
- Author(s)
  Shinojima, T., Oya, M., Takayanagi, A., Mizuno, R., Shimizu, N., Murai, M.
- Journal Title
  
  Carcinogenesis 28
  
  Pages: 529-536
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Renal cancer cells lacking hypoxia inducible factor (HIF) 1-α expression maintain vascular endothelial growth factor expression through HIF 2-α.2007
- Author(s)
  Shinojima, T., Oya, M., Takayanagi, A., Mizuno, R., Shimizu, N., Murai, M.
- Journal Title
  
  Carcinogenesis 28
  
  Pages: 529-536
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Angiotensin II type 1 receptor antagonist as an angiogenic inhibitor in prostate cancer2007
- Author(s)
  Kosaka T, Miyajima A, Takayama E, Kikuchi E, Nakashima J, Ohigashi T, Asano T, Sakamoto M, Okita H, Murai M, Hayakawa M
- Journal Title
  
  Prostate 67
  
  Pages: 41-9
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Interleukin 6 is associated with cachexia in patients with prostate cancer2007
- Author(s)
  Kuroda K, Nakashima J, Kanao K, Ekikuchi E, Miyajima A, Horiguchi Y, Nakagawa K, Oya M, Ohigashi T, Murai M
- Journal Title
  
  Urology 69(1)
  
  Pages: 113-117
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Interleukin 6 is associated with cachexia in patients with prostate cancer2007
- Author(s)
  Kuroda K, Nakashima J, Kanao K, Ekikuchi E, Miyajima A, Horiguchi Y, Nakagawa K, Oya M, Ohigashi T, Murai M
- Journal Title
  
  Urology 69
  
  Pages: 113-117
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Maximum tumor diameter is a simple and valuable index associated with the local extent of disease in clinically localized prostate cancer.2006
- Author(s)
  Mizuno R, Nakashima J, Mukai M, Ookita H, Nakagawa K, Oya M, Ohigashi T, Marumo K, Murai M
- Journal Title
  
  Int J Urol 13(7)
  
  Pages: 951-955
- NAID
  10018173400
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Candesartan as an angiogenic inhibitor in a xenograft model of bladder cancer.2006
- Author(s)
  Kosugi M, Miyajima A, Kikuchi E, Horiguchi Y, Murai M
- Journal Title
  
  Clin Cancer Res 12(9)
  
  Pages: 2888-2893
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Maximum tumor diameter is a simple and valuable index associated with the local extent of disease in clinically localized prostate cancer.2006
- Author(s)
  Mizuno R, Nakashima J, Mukai M, Ookita H, Nakagawa K, Oya M, Ohigashi T, Marumo K, Murai M
- Journal Title
  
  Int J Urol 13
  
  Pages: 951-955
- NAID
  10018173400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Maximum tumor diameter is a simple and valuable index associated with the local extent of disease in clinically localized prostate cancer.2006
- Author(s)
  Mizuno R, Nakashima J, Mukai M, Ookita H, Nakagawa K, Oya M, Ohigashi T, Marumo K, Murai M.
- Journal Title
  
  Int J Urol 13
  
  Pages: 951-955
- NAID
  10018173400
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Candesartan as an angiogenic inhibitor in a xenograft model of bladder cancer.2006
- Author(s)
  Kosugi M, Miyajima A, Kikuchi E, Horiguchi Y, Murai M
- Journal Title
  
  Clin Cancer Res 12
  
  Pages: 2888-2893
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Expression of Ets-1 in human clear cell renal cell carcinomas : implications for angiogenesis.2006
- Author(s)
  Mikami, S., Oya, M., Mizuno, R., Murai, M., Mukai, M., Okada, Y.
- Journal Title
  
  Cancer Sci 97
  
  Pages: 875-882
- NAID
  10018767423
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Expression of Ets-1 in human clear cell renal cell carcinomas : implications for angiogenesis.2006
- Author(s)
  Mikami, S., Oya, M., Mizuno, R., Murai, M., Mukai, M., Okada, Y.
- Journal Title
  
  Cancer Sci. 97
  
  Pages: 875-882
- NAID
  10018767423
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Maximum tumor diameter is a smple and valuable index associated with the local extent of disease in clinically localized prostate cancer.2006
- Author(s)
  Mizuno, R., Nakashima, J., Mukai, M., Ookita, H., Nakagawa, K., Oya, M., Ohigashi, T., Marumo, K., Murai, M.
- Journal Title
  
  Int. J. Urol 13
  
  Pages: 951-955
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Survivin associates with cell proliferation in renal cancer cells : Regulation of survivin expression by insulin-like growth factor-1, interferon-gamma and a novel NF-kappaB inhibitor.2006
- Author(s)
  Sato A., Oya, M., Ito K., Mizuno, R., Horiguchi, Y., Ohigashi, T., Umezawa K., Hayakawa M., Murai, M.
- Journal Title
  
  Int.J.Oncol. 28
  
  Pages: 841-846
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Survivin associates with cell proliferation in renal cancer cells : Regulation of survivin expression by insulin-like growth factor-1, interferon-gamma and a novel NF-kappaB inhibitor.2006
- Author(s)
  Sato A., Oya, M., Ito K., Mizuno, R., Horiguchi, Y., Ohigashi, T., Umezawa K., Hayakawa M., Murai, M.
- Journal Title
  
  Int. J. Oncol 28
  
  Pages: 841-846
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Survivin associates with cell proliferation in renal cancer cells : regulation of survivin expression by insulin-like growth factor-1, interferon-gamma and a novel NF-kappaB inhibitor2006
- Author(s)
  Murai M, et al.
- Journal Title
  
  Int J Oncol.. 28・4
  
  Pages: 841-6
- Data Source
  KAKENHI-PROJECT-18591774
[Journal Article] Prevention of cancer cachexia by a novel nuclear factor {kappa}B inhibitor in prostate cancer.2005
- Author(s)
  Kuroda K, Horiguchi Y, Nakashima J, Kikuchi E, Kanao K, Miyajima A, Ohigashi T, Umezawa K, Murai M
- Journal Title
  
  Clin. Cancer Res. 11(15)
  
  Pages: 5590-5594
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Prevention of cancer cachexia by a novel nuclear factor {kappa}B inhibitor in prostate cancer.2005
- Author(s)
  Kuroda K, Horiguchi Y, Nakashima J, Kikuchi E, Kanao K, Miyajima A, Ohigashi T, Umezawa K, Murai M.
- Journal Title
  
  Clin. Cancer Res 11
  
  Pages: 5590-5594
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Repeated regression of pulmonary metastases from renal cell carcinoma after treatment using different interferon-alfa preparations.2005
- Author(s)
  Oya, M., Asakura, H., Mizuno, R., Marumo, K., Murai, M.
- Journal Title
  
  Biomed Res 26
  
  Pages: 135-137
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Prevention of cancer cachexia by a novel nuclear factor {kappa}B inhibitor in prostate cancer.2005
- Author(s)
  Kuroda K, Horiguchi Y, Nakashima J, Kikuchi E, Kanao K, Miyajima A, Ohigashi T, Umezawa K, Murai M
- Journal Title
  
  Clin. Cancer Res. 11
  
  Pages: 5590-5594
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells.2005
- Author(s)
  Ohigashi T, Mizuno R, Nakashima J, Marumo K, Murai M
- Journal Title
  
  Prostate 62
  
  Pages: 61-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Modulation of bcl-2 family proteins in MAPK independent apoptosis induced by a cdc25 phosphatase inhibitor Cpd 5 in renal cancer cells.2005
- Author(s)
  Mizuno, R., Oya, M., Hara, S, Matsumoto, M, Horiguchi, A, Ohigashi, T, Marumo, K, Murai, M.
- Journal Title
  
  Oncol.Rep. 14
  
  Pages: 639-644
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Akt activation in renal cell carcinoma : contribution of a decreased PTEN expression and the induction of apoptosis by an Akt inhibitor.2005
- Author(s)
  Hara, S., Oya, M., Mizuno, R., Horiguchi, A., Marumo, K., Murai, M.
- Journal Title
  
  Ann Oncol 16
  
  Pages: 928-933
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells.2005
- Author(s)
  Ohigashi T, Mizuno R, Nakashima J, Marumo K, Murai M
- Journal Title
  
  Prostate 62(1)
  
  Pages: 61-68
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Clinical and pathological significance of activation of signal transducer and activator of transcription 3 in prostate cancer.2005
- Author(s)
  Horingaga M, Okita H, Nakashima J, Kanao K, Sakamoto M, Murai M
- Journal Title
  
  Urology 66(3)
  
  Pages: 671-675
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Modulation of bcl-2 family proteins in MAPK independent apoptosis induced by a cdc25 phosphatase inhibitor Cpd 5 in renal cancer cells.2005
- Author(s)
  Mizuno, R., Oya, M., Hara, S., Matsumoto, M., Horiguchi, A., Ohigashi, T., Marumo, K., Murai, M.
- Journal Title
  
  Oncol Rep 14
  
  Pages: 639-644
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] C-jun activation in acquired cystic kidney disease and renal cell carcinoma.2005
- Author(s)
  Oya, M., Mikami, S., Mizuno, R., Marumo, K., Mukai, M., Murai, M.
- Journal Title
  
  J.Urol. 174
  
  Pages: 726-730
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Clinical and pathological significance of activation of signal transducer and activator of transcription 3 in prostate cancer.2005
- Author(s)
  Horingaga M, Okita H, Nakashima J, Kanao K, Sakamoto M, Murai M
- Journal Title
  
  Urology 66
  
  Pages: 671-675
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Modulation of bcl-2 family proteins in MAPK independent apoptosis induced by a cdc25 phosphatase inhibitor Cpd 5 in renal cancer cells.2005
- Author(s)
  Mizuno, R., Oya, M., Hara, S., Matsumoto, M., Horiguchi, A., Ohigashi, T., Marumo, K., Murai, M.
- Journal Title
  
  Oncol. Rep 14
  
  Pages: 639-644
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] C-jun activation in acquired cystic kidney disease and renal cell carcinoma.2005
- Author(s)
  Oya, M., Mikami, S., Mizuno, R., Marumo, K., Mukai, M., Murai, M.
- Journal Title
  
  J. Urol. 174
  
  Pages: 726-730
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells.2005
- Author(s)
  Ohigashi T, Mizuno R, Nakashima J, Marumo K, Murai M.
- Journal Title
  
  Prostate 62(1)
  
  Pages: 61-68
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Akt activation in renal cell carcinoma : contribution of a decreased PTEN expression and the induction of apoptosis by an Akt inhibitor.2005
- Author(s)
  Hara, S., Oya, M., Mizuno, R., Horiguchi, A., Marumo, K., Murai, M.
- Journal Title
  
  Ann.Oncol. 16
  
  Pages: 928-933
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Akt activation in renal cell carcinoma : contribution of a decreased PTEN expression and the induction of apoptosis by an Akt inhibitor.2005
- Author(s)
  Hara, S., Oya, M., Mizuno, R., Horiguchi, A., Marumo, K, Murai, M.
- Journal Title
  
  Ann. Oncol. 16
  
  Pages: 928-933
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Clinical and pathologic significance of activation of signal transducer and activator of transcription 3 in prostate cancer2005
- Author(s)
  Horinaga M, Murai M, et al.
- Journal Title
  
  Urology 66(3)
  
  Pages: 671-675
- Data Source
  KAKENHI-PROJECT-16591620
[Journal Article] C-jun activation in acquired cystic kidney disease and renal cell carcinoma.2005
- Author(s)
  Oya, M., Mikami, S., Mizuno, R., Marumo, K., Mukai, M., Murai, M.
- Journal Title
  
  J Urol 174
  
  Pages: 726-730
- Data Source
  KAKENHI-PROJECT-17591701
[Journal Article] Differential expression of activator protein-2 isoforms in renal cell carcinoma.2004
- Author(s)
  Oya, M., Mikami, S., Mizuno, R., Miyajima, A., Horiguchi, Y., Nakashima, J., Marumo, K., Mukai, M., Murai, M.
- Journal Title
  
  Urology 64
  
  Pages: 162-167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571522
[Journal Article] Inhibition of the ubiquitin-proteasome pathway activates stress kinases and induces apoptosis in renal cancer cells.2004
- Author(s)
  Ishizawa, J., Yoshida S., Oya, M., Mizuno, R., Shinojima, T., Marumo, K., Murai, M.
- Journal Title
  
  International Journal of Oncology 25
  
  Pages: 697-702
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571522
[Journal Article] Inhibition of the ubiquitin-proteasome pathway activates stress kinases and induces apoptosis in renal cancer cells.2004
- Author(s)
  Ishizawa, J., Yoshida S., Oya, M., Mizuno, R., Shinojima, T., Marumo, K., Murai, M.
- Journal Title
  
  International Journal of Oncology 25
  
  Pages: 697-702
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591715
[Journal Article] Differential expression of activator protein-2 isoforms in renal cell carcinoma.2004
- Author(s)
  Oya M, Mikami S, Mizuno R, Miyajima A, Horiguchi Y, Nakashima J, Marumo K, Mukai M, Murai M.
- Journal Title
  
  Urology 64
  
  Pages: 162-167
- Data Source
  KAKENHI-PROJECT-16390469
[Journal Article] Differential expression of activator protein-2 isoforms in renal cell carcinoma.2004
- Author(s)
  Oya, M., Mikami, S., Mizuno, R., Miyajima, A., Horiguchi, Y., Nakashima, J., Marumo, K., Mukai, M., Murai, M.
- Journal Title
  
  Urology 64
  
  Pages: 162-167
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591715
[Journal Article] Renal cell carcinoma : etiology, incidence and epidemiology.2004
- Author(s)
  Murai, M., Oya, M.
- Journal Title
  
  Curr.Opin.Urol. 14
  
  Pages: 229-233
- Data Source
  KAKENHI-PROJECT-15591715
[Journal Article] Inhibition of MKP-1 expression potentiates JNK related apoptosis in renal cancer cells.2004
- Author(s)
  Mizuno, R., Oya, M., Shiomi, T., Marumo, K., Okada, Y., Murai, M.
- Journal Title
  
  Journal of Urology 172
  
  Pages: 723-727
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571522
[Journal Article] Inhibition of MKP-1 expression potentiates JNK related apoptosis in renal cancer cells.2004
- Author(s)
  Mizuno, R., Oya, M., Shiomi, T., Marumo, K., Okada, Y., Murai, M.
- Journal Title
  
  Journal of Urology 172
  
  Pages: 723-727
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591715
[Journal Article] Suppression of hormone-refractory prostate cancer by a novel nuclear factor κB inhibitor in nude mice2003
- Author(s)
  KIKUCHI E., HORIGUCHI Y., NAKASHIMA J, KURODA K., OYA M., OHIGASHI T., TAMAHASHI N., SHIMA Y., UMEZAWA K., MURAI M
- Journal Title
  
  Cancer research 63
  
  Pages: 107-110
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571522
[Journal Article] Pediction of extraprostatic cancer by prostate specific antigen density, endorectal MRI, and biopsy Gleason score in clinically localized prostate cancer2003
- Author(s)
  HORIGUCHI A., NAKASHIMA J., HORIGUCHI Y., NAKAGAWA K., OYA M., OHIGASHI T., MARUMO K., MURAI M.
- Journal Title
  
  Prostate 56
  
  Pages: 23-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571522
[Journal Article] Enhancement of diethylstilbestrol induced cytotoxicity by bcl-2 antisense oligodeoxynucleotides and a glutathione depletor for prostate cancer2003
- Author(s)
  KIKUCHI E., NAKASHIMA J., HORIGUCHI Y., OYA M., OHIGASHI T., MURAI M
- Journal Title
  
  The Journal of Urology 169
  
  Pages: 730-734
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571522
[Journal Article] Elevated AKT activation and its impact on clinicopathological features of renal cell carcinoma.2003
- Author(s)
  Horiguchi, A., Oya, M., Shimada, T., Uchida, A., Marumo, K., Murai, M
- Journal Title
  
  Journal of Urology 169
  
  Pages: 710-713
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591715
[Journal Article] Increased nuclear factor-κB activation is related to the tumor development of renal cell carcinoma.2003
- Author(s)
  Oya, M., Takayanagi, A., Horiguchi, A., Mizuno, R., Ohtsubo, M., Marumo, K., Shimizu, N., Murai, M.
- Journal Title
  
  Carcinogenesis 24
  
  Pages: 377-384
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591715
[Journal Article] Increased activation of CCAAT/enhancer binding protein-β correlates with the invasiveness of renal cell carcinoma.2003
- Author(s)
  Oya, M., Horiguchi, A., Mizuno, M., Marumo, K., Murai, M.
- Journal Title
  
  Clinical Cancer Research 9
  
  Pages: 1021-1027
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571522
[Journal Article] Increased activation of CCAAT/enhancer binding protein-β correlates with the invasiveness of renal cell carcinoma.2003
- Author(s)
  Oya, M., Horiguchi, A., Mizuno, M., Marumo, K., Murai, M.
- Journal Title
  
  Clinical Cancer Research 9
  
  Pages: 1021-1027
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591715
[Journal Article] Elevated AKT activation and its impact on clinicopathological features of renal cell carcinoma.2003
- Author(s)
  Horiguchi, A., Oya, M., Shimada, T., Uchida, A., Marumo, K., Murai, M
- Journal Title
  
  Journal of Urology 169
  
  Pages: 710-713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571522
[Journal Article] Increased nuclear factor-κB activation is related to the tumor development of renal cell carcinoma.2003
- Author(s)
  Oya, M., Takayanagi, A., Horiguchi, A., Mizuno, R., Ohtsubo, M., Marumo, K., Shimizu, N., Murai, M.
- Journal Title
  
  Carcinogenesis 24
  
  Pages: 377-384
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571522
[Journal Article] Candesartan as an angiogenic inhibitor in a xenograft model of bladder cancer
- Author(s)
  Kosugi M, Miyajima A, Kikuchi E, Horiguchi Y, Murai M.
- Journal Title
  
  Clin Cancer Res, (印刷中)
- Data Source
  KAKENHI-PROJECT-16591621

1. NAKASHIMA Jun (10167546)

# of Collaborated Projects: 18 results

# of Collaborated Products: 19 results
2. OYA Mototsugu (00213885)

# of Collaborated Projects: 12 results

# of Collaborated Products: 39 results
3. OHIGASHI Takashi (80185371)

# of Collaborated Projects: 11 results

# of Collaborated Products: 15 results
4. TACHIBANA Masaaki (70129526)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
5. HORIGUCHI Yutaka (60229234)

# of Collaborated Projects: 7 results

# of Collaborated Products: 16 results
6. MIYAJIMA Akira (90245572)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
7. ASAKURA Hirotaka (50175840)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
8. MARUMO Ken (80138130)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
9. BABA Shiro (00051889)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. NAKAMURA Kaoru (10146673)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. KIKUCHI Eiji (10286552)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. MIYAKAWA Harumi (40239356)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. OZU Choichiro (90296674)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. SAITO Shiro (80170504)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. OYAMA Masafumi (70276351)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. IKEDA Hideyuki (40301494)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. KAWAKAMI Yutaka (50161287)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. NAKAGAWA Ken (50227740)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. TAZAKI Hiroshi (90051268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. FUJITA Tomonobu (20199334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. HATA Junichi (90051614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SUZUKI Yuriko (40255435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YAZAKI Takahito (80200484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NAKAJIMA Fumio (10159064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SATOH Akinori (00296675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. OHKI Takahiro (50265948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. YAMADA Taketo (60230463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. HOZUMI Nobumichi (60051744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. UMEZAWA Kazuo (70114402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KOSUGI Michio (10317216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. KOUNO Hidaka (50338133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 堀口明男 (20286553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 西山徹 (60255536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 手塚健一 (50236973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 篠島利明 (60306777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. ITO Fumio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 梅沢一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
38. 宮島哲

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results

MURAI Masaru 村井 勝

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Pathophysiological role of NF k B and the efficacy of a novel NF K B inhibitor in urological cancersPrincipal Investigator

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Establishment of gene therapy targeting bcl-2 and NF κB for urological malignanciesPrincipal Investigator

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Establishment of a novel mouse model for studying prostate cancer metastasis to human bone and new therapeutic strategies.Principal Investigator

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MURAI Masaru 村井勝