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Todoki Kazuo  塗々木 和男

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TODOKI Kazuo  塗々木 和男

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Researcher Number 90139577
External Links
Affiliation (Current) 2025: 神奈川歯科大学短期大学部, その他部局等, 特任教授
Affiliation (based on the past Project Information) *help 1988 – 2006: KANAGAWA DENTAL COLLEGE ・ lecturer, 歯学部, 講師
1997: 神奈川歯大, 歯学部, 講師
1986 – 1987: Kanagawa Dental College, 歯学部, 助手
Review Section/Research Field
Principal Investigator
Functional basic dentistry
Except Principal Investigator
Functional basic dentistry / 応用薬理学・医療系薬学 / 補綴理工系歯学 / Surgical dentistry
Keywords
Principal Investigator
nitric oxide / L-NAME / 口腔組織 / Ischemia / フリーラジカル / ルミノール / 過酸化水素 / 化学発光 / 虚血 / Oxygen free radicals … More / 一酸化窒素 / bradykinin / in vivo / Laser Lppler flowmetry / gingival blood flow / electrochemical probe / reactive hyperemia / (8)フェントン反応 / (7)ペルオキシダーゼ / (6)Cu,Zn-SOD / (5)バイオセンサー / (4)デフェロキサミン / (3)化学発光 / (2)ルミノール / (1)活性酸素フリーラジカル / 局所循環調節 / 歯肉 / 活性酸素 / ペルオキシダーゼ / カタラーゼ / デフェロキサミン / レーザードップラー血流計 / 歯肉血流量 / 電気化学電極 / 反応性充血 / three-dimensional imaging / in vivo electron spin resonance / nitroxyl radical spin probe / electron spin resonance imaging / free radical / L-バンド / ESR画像 / スピンラベル / 血液-脳関門 / in vivo ESR / 頭部イメージング / スピンプローブ / 電子磁気共鳴(ESR) / 活性酸素ラジカル / Plasuma / Luminol / Hydrogen peroxide / Chemiluminescence / Hypoxanthine / Optical biosensor / 血漿 / 酸素フリーラジカル / ヒポキサンチン / オプティカルバイオセンサー / Prostanoide / Endothelium / Lingual artery / Endotoxin / Periodontal disease / B_<2->受容体 / B_<1->受容体 / 収縮 / 内皮細胞由来弛緩因子 / エンドトキシン / 電子スピン共鳴法 / 内皮由来弛緩因子(EDRF) / 血管平滑筋 / プロスタノイド / 活性酸素種ラジカル / 内皮細胞 / 舌動脈 / エンドトキシン(LPS) / 歯周疾患 … More
Except Principal Investigator
フリーラジカル / カルシウム / 内皮細胞 / Calcium / Free radicals / エンドトキシン / カルモジュリン / Ischemia / 心筋小胞体 / 心筋虚血 / statin / PGA / PRP / bFGF / 17-estradiol / Poly(LA-CL) / 一酸化窒素 / カルシトニン遺伝子関連ペプチド / 歯周疾患 / Calmodulin / Sarcoplasmic reticulum / 筋小胞体 / 興奮-収縮連関 / 活性酸素ラジカル / 咬筋 / Microcirculation / Vascular smooth muscle / 舌動脈 / 電子スピン共鳴 / 微小循環 / 血管平滑筋 / 口腔 / ヒドロキシルラジカル / Coronary Vessel / Sarcoplasmic Reticulum / Free Radical / 筋鞘 / 冠血管 / 心筋形質膜 / adenosine 5'-monophosphate (5'AMP) / adenosine 5'-diphosphate (5'ADP) / peripheral vasodilation / vasoactive substance / fur seal / skeletal muscle / 二重盲検法 / 微小血管 / ハムスターチークポーチ / オットセイ骨格筋抽出血管活性ペプチド / ヒスタミン / カルノシン / 5′-ADP / 5′-AMP / 血小板凝集抑制 / 下肢灌流法 / 血管拡張 / 生理活性 / 分画 / オットセイ骨格筋肉抽出血管活性ペプチド / Free radical / endotoxin / blood flow / B 2-kinin receptor / prostaglandins / kinins / vasocontraction / vasodilation / microcirculation / gingiva / tongue / dental pulp / bradykinin / 収縮反応 / 弛緩反応 / 内皮細胞依存性 / ブラジキニン / 内皮細胞由来弛緩因子 / 内因性血管活性物質 / 歯髄循環調節機構 / 口腔内微小循環動態 / Dentures / Memory / Pre-frontal cortex / Hippocampus / Functional MRI / Mastication / Occulusion / Dementia / 神経ネットワーク / 磁器共鳴機能画像 / 認知障害 / 痴呆 / 義歯 / 記憶 / 前頭前野 / 海馬 / 磁気共鳴機能画像 / 咀嚼 / 咬合 / 認知症 / jawbone / regenerative medicine / PLLA / GBR / DDS / 骨髄間葉系細胞 / 徐放 / hPTH / β-estradiol / scaffold / PTH / 17-cstradiol / 顎骨再生 / 骨髄間葉系幹細胞 / 顎骨 / 再生医療 / スタチン / ENDOTHELIAL CELL / α-ADRENOCEPTOR / REACTIVE OXYGEN SPECIES / VASCULAR SMOOTH MUSCLE / PROPOFOL / 血管内皮細胞 / α-受容体 / 活性酸素ラジカル種 / propofol / Spin-trap / Oral tissues / Nitric oxide / Electron spin resonance / スピントラップ / 口腔組織 / 電子磁気共鳴 / Lingual artery / Signal transduction / Dental pulp / Calcitonin gene-related peptide / 歯髄 / NANC神経 / CGRP / 一重項酸素 / スーパーオキシドラジカル / 血管反応 / 細胞内情報伝達系 / 歯髄循環 / Lipopolysaccharides / Periodontitis / Endothelial cells / Vasoactive substances / 口腔内血管 / 血管活性物質 / Ca^<2+> release channel / Excitation-contraction coupling / Masseter muscle / NaーCa交換系 / 興奮ー収縮連関 / 酸素ラジカル / カルシウムイオン / カルシウムチャンネル / Oxygen free radicals / Kinins / Endotoxin / 神経性血管調節 / 内因性血管作動物質 / キニン受容体誘導 / 活性酸素フリ-ラジカル / キニン / ESR imaging / ニトロオキシドラジカル / 脳 / 酸化ストレス / ESR Imaging / ニトロキシドラジカル / 電子スピン共鳴(ESR)法 / 神経伝達 / 電子磁気共鳴(ESR) / 交感神経 / ノルアドレナリン Less
  • Research Projects

    (18 results)
  • Co-Researchers

    (29 People)
  •  Preventive effects of masticatory stimulus on senile dementia : a fMRI study

    • Principal Investigator
      ONOZUKA Minoru
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      補綴理工系歯学
    • Research Institution
      Kanagawa Dental College
  •  Regenerative Medicine of the Jawbone Using Mesechymal Stem Cells and /or Bioactive Factors

    • Principal Investigator
      KINOSHITA Yukihiko
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kanagawa Dental College
  •  頭部口腔領域におけるフリーラジカルin vivo三次元イメージングとその応用

    • Principal Investigator
      久保田 英朗
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  歯髄-口腔粘膜血管反応調節に連関する活性酸素ラジカルの分子機構

    • Principal Investigator
      OKABE Eiichiro
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Monitoring of oxygen-derived radicals : development and appplication of optical biosensor to oral tissues under pathological conditionsPrincipal Investigator

    • Principal Investigator
      TODOKI Kazuo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Production and degradation of active oxygen-derived free radicals in oral region : the imaging of free radicals using by the in vivo electron spin resonance (ESR) imaging system.Principal Investigator

    • Principal Investigator
      TODOKI Kazuo, 岡部 栄一郎
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  PROTECTIVE EFFECT OF PROPOFOL ON FREE RADICAL INDUCED IMPAIRMENT OF VASCULAR SMOOTH MUSCLE REACTIVITY.

    • Principal Investigator
      KOBAYASHI Yutaka
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KANAGAWA DENTAL COLLEGE
  •  Molecular-Pharmacological Analysis of Periodontal Disease : Interaction between LPS and Kinins on Microcirculation of Oral RegionPrincipal Investigator

    • Principal Investigator
      TODOKI Kazuo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Development and Application of Bioradical Detecting System for Oral Tissues : A Basic Research

    • Principal Investigator
      OKABE Eiichiro
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Tissue Function-Reactive Oxygen Cross-talk in Oral Region : Its Pathopharmacological Analysis

    • Principal Investigator
      OKABE Eiichiro
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Mode of Action of Endogenous Vasoactive Substances on Blood Vessels in Oral Region : Its Molecular Pharmacological Analysis

    • Principal Investigator
      ITO Haruo
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Mode of Action of Oxygen Free Radicals in Excitation-Contraction Coupling System of Masseter Muscle

    • Principal Investigator
      OKABE Eiichiro
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Molecular-Pharmacological Analysis of Periodontal Disease : Interaction between LPS and Kinins on Microcirculation of Oral RegionPrincipal Investigator

    • Principal Investigator
      TODOKI Kazuo
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Phathophysiology of Circulatory Failure in Oral Region : Its Pharmacological Analysis

    • Principal Investigator
      ITO Haruo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Mechanism of Oxygen Free Radical-Induced Cellular Damage in Myocardium

    • Principal Investigator
      OKABE Eiichiro
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kanagawa Dental College
  •  Basic and clinical research for periodontal disease of physiologically vasoactive substances extracted from skeletal muscle of fur seal

    • Principal Investigator
      ITO Haruo
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      KANAGAWA DENTAL COLLEGE
  •  Pharmacological analysis on the role of endogenous vasoactive substances in regulating mechanism of microcircuatory dynamics in oral region.

    • Principal Investigator
      ITHO HARUO
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KANAGAWA DENTAL COLLEGE
  •  Myocardial Ischemia and Cell Functions - Characterization of Free Radical-Induced Dysfunction of Sarcoplasmic Reticulum Calcium Transport and Excitation-Contraction Coupling System in Myocardium -

    • Principal Investigator
      OKABE Eiichiro, 岡部 栄逸郎
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kanagawa Dental College
  • 1.  OKABE Eiichiro (50097276)
    # of Collaborated Projects: 15 results
    # of Collaborated Products: 0 results
  • 2.  TAKAHASHI Shun-suke (60206810)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  LEE Masaichi (60220795)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 4.  SHOJI Hirofumi (90277913)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  ITO Haruo (10084716)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  KOBAYASI Utaka (50130919)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  TOMIKAWA Shigeji (40197918)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  TOKUTOMI WATARU (30147996)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  TAMURA Kengi (20163686)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  HARA AKIRA (90121029)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  KOHNO Masahiro
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  KINOSHITA Yukihiko (70084770)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TABATA Yasuhiko (50211371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  IKADA Yoshito (00025909)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KAWASE Toshio (30084784)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  OZONO Satoru (40084785)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  ONOZUKA Minoru (90084780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SATO Sadao (00084799)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  UEMATSU Hiroshi (80100957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  KATO Norihiro (40224521)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  KANEMATSU Masayuki (40252134)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  WATANABE Kazuko (40158621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  久保田 英朗 (50170030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  吉野 文彦 (20308307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  西山 勝弘 (20084783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  中山 義之 (70084712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  HORI Toshio (80084721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  岡部 栄逸郎
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  NAKAYAMA Yoshiyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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