YASUJIMA Minoru 保嶋実

… Alternative Names

土屋滋

久嶋実

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Researcher Number	90142934
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007 – 2011: Hirosaki University, Graduate School of Medicine, Professor 1997 – 2006: 弘前大学, 医学部, 教授 1995: Tohoku University, School of Medicine Dept. of Labo. Med. Prof., 医学部, 教授 1992 – 1994: 東北大学, 医学部, 助教授 1989: Tohoku Univ. Sch of Med., Associate Professor, 医学部, 助教授 … More 1988: 東北大学, 医学部, 助手 1988: 東北大学, 抗酸菌病研究所, 助教授 1987 – 1988: 東北大学, 医学部付属病院, 助手 Less
Review Section/Research Field	Principal Investigator Laboratory medicine / Circulatory organs internal medicine / Laboratory medicine Except Principal Investigator Laboratory medicine / Circulatory organs internal medicine / Pediatrics / Laboratory medicine
Keywords	Principal Investigator 連関解析 / 高血圧 / 一塩基多型(SNPs) / 遺伝子多型 / 糖尿病性腎症 / Hypertension / end-stage renal disease / restriction enzyme fragment length polymorphism (RFLP) / hypertension / gene polymorphism … More / アンジオテンシン変換酵素 / in vitro autoradiography / radioinhibitory binding assay / neutral metalloendopeptidase / サイアザイド感受性NaCl共輸送体 / Vasodilatation / Natriuresis / Cyclic GMP / Heart failure / Renal failure / Atrial natriuretic Factor (ANF) / Na代謝 / 血管作用 / 腎作用 / cyclic nucleotides / 高血圧自然発症ラット(SHR) / DOCA食塩高血圧ラット / 腎摘除腎不全モデルラット / 培養血管平滑筋細胞 / 単離尿細管 / cycle nucleotides / 心房性Na利尿因子(ANF) / 腎摘除腎不全ラット / 食塩依存性高血圧ラット / 心房性Na利尿ホルモン / 血管拡張作用 / Na利尿作用 / cyclic GMP / 心不全 / 腎不全 / 心房性Na利尿因子 / Linkage analysis / Single nucleotide polymorphisms / Mutation / Thiazide-sensitive Na-Cl cotransporter / Gitelman's syndrome / サイアザイド感受性Na-Cl共輸送体 / 変異 / Gitelman症候群 / Y chromosome Alu insertion polymorphism / D polymorphism / angiotensin coverting enzyme I / diabetic nephropathy / chronic glomerulonephritis / a多型 / 4b / Glu298Asp / 弥生系 / 縄文系 / 遺伝子相互作用 / 内皮型NO合成酵素 / Y染色体Alu反復多型 / D多型 / ACE I / 慢性糸球体腎炎 / 腎障害 / RFLP / cardiovascular diseases / angiotensin II type 1 receptor / angiotensin converting enzyme / angiotensinogen / 高脂血症 / 糖尿病 / アンジオテンシン変換酵素遺伝子多型 / 維持血液透析 / 終末期腎不全 / 糸球体腎炎 / アンジオテンシンII1型受容体遺伝子多型 / アンジオテンシノーゲン遺伝子多型 / 脳卒中 / 脳梗塞 / 脳出血 / 高血圧症 / アンジオテンシンII1型受容体 / アンジオテンシノーゲン / rat kidney / radio-labeled NEP inhibitor / NEP inhibitor / neutral metalloendopeptidase(NEP) / ラット腎 / 標識NEP阻害薬 / NEP阻害薬 / SLC12A3 / 遺伝子マーカー / Gitelman's症候群 / アルドステロン / CYP11B2 … More Except Principal Investigator 糖尿病 / LFA-1 / インスリンシグナル / 神経障害 / monoclonal antibody / HLA-mismatch / graft rejection / bone marrow transplantation / モノクローナル抗体 / CD_<18> / CD_<11>a / HLA不一致 / 単クロ-ン抗体 / HLA不適合 / 移植片拒絶 / LFAー1 / 骨髄移植 / Prostaglandin / Bradykinin / Inostol Metabolites / HPLC / Laser-excitation fluorescence microscopy / Fura-2 / Intracellular Calcium / Atrial Natriuretic Peptide / バゾプレシン / アンジオテンシンII / イノシトール燐酸 / レ-ザ-顕微鏡 / 心房性利尿ペプチド / バソプレッシン / アンギオランシンII / カルシウム / イノシト-ル隣酸 / 血管平滑筋 / 腎ネフロン / cGMP / cAMP / 腎髄質乳頭部集合管 / 賢ネフロン / 細胞内セカンドメッセンジャ- / 細胞培養 / CGMP / CAMP / プロスタグランディンE_2 / 高血圧自然発症ラット / 賢髄質乳頭部集合管 / Impaired glucose tolerance / Diabetes / Neuropathy / Metabolic syndrome / Insulin resistance / Insulin signaling / 代謝異常 / メタポリックシンドローム / 耐糖能障害 / メタボリックシンドローム / インスリン抵抗性 / mass spectrometry / microarray / peripheral CD34(+) stem cell / vasopressin / microRNA / gene expression / バゾプレシンV1a受容体 / 生体分子 / シグナル伝達 / 遺伝子 / 質量分析 / マイクロアレイ / CD34陽性末梢血液幹細胞 / バソプレシン / マイクロRNA / 遺伝子発現 / hypertension / mitochondrial DNA polymorphism / Alu insertion / Y chromosomal polymorphism / ethnicity / 遺伝子相互作用 / アルデヒド脱水素酵素遺伝子多型 / 糖尿病性腎症 / 一塩基多型(SNPs) / バゾプレシンVla受容体 / Alu反復 / Y染色体遺伝子多型 / 民族差 / 高血圧 / ミトコンドリアDNA多型 / Alu挿入 / Y染色体多型 / 人種差 / Rat / Renal failure / Heart failure / Losartan / Kinin / ACE inhibitor / Angiotensin Converting enzyme / Angiotensin / HOE140 / erythropoietin / losartan / ラット / 腎不全 / 心不全 / ロサルタン / キニン / ACE阻害薬 / アンジオテンシン変換酵素 / アンジオテンシン / 共焦点レーザー顕微鏡 / インスリン作用 / 病期 / インスリンシグナル異常 / 病期分類 / 痛覚 / 3次元画像解析 / 表皮内神経線維 Less

Elucidation of time course and molecular mechanism of intraepidermal nerve fiber loss in diabetic polyneuropathy
- Principal Investigator
  
  SUGIMOTO Kazuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hirosaki University
Clinical significance of SLC12A3 gene polymorphisms in diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  YASUJIMA Minoru
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hirosaki University
Molecular and pathogenic mechanisms for peripheral neuropathy associated with metabolic syndrome
- Principal Investigator
  
  SUGIMOTO Kazuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hirosaki University
Molecular analysis of heterogeneity in human platelet aggregation response
- Principal Investigator
  
  SHOJI Masaru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hirosaki University
Clinical Significance of Sodium Metabolism-related Gene Polymorphisms in Salt-Sensitive HypertensionPrincipal Investigator
- Principal Investigator
  
  YASUJIMA Minoru
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hirosaki University
Ethnic differences in genetic markers for hypertension in the two major lineages of modern Japanese, Jomon and Yayoi
- Principal Investigator
  
  SHOJI Masaru
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hirosaki University
The significance of endothelial nitric oxide synthase gene polymorphisms as genetic markers of hypertensive disordersPrincipal Investigator
- Principal Investigator
  
  YASUJIMA Minoru
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hirosaki University
ナトリウム代謝感受性遺伝子多型および変異の検査同定法の確立とその臨床応用Principal Investigator
- Principal Investigator
  
  保嶋実
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hirosaki University
Pathological Significance of Gene Polymorphisms of the Renin-Angiotensin System in Hypertension.Principal Investigator
- Principal Investigator
  
  YASUJIMA Minoru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  HIROSAKI UNIVERSITY
The role of tissue renin-angiotensin system on cardiovascular and renal hypertrophy/hyperplasia
- Principal Investigator
  
  KOHZUKI Masahiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  TOHOKU UNIVERSITY
Characterization, localization and quantification of neutral metalloendopeptidase, the degradative enzyme for atrial natriuretic peptidePrincipal Investigator
- Principal Investigator
  
  YASUJIMA Minoru
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tohoku University
Regulatory Mechanism of Biosynthesis and Cellular Action of Renal Vasoactive Hormones.
- Principal Investigator
  
  ABE Keishi
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tohoku University
Anti-human LFA-1 monoclonal antibodies for prevention of graft failure in HLA-mismatched bone marrow transplantation.
- Principal Investigator
  
  KONNO Tasuke
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
Roles of atrial natriuretic factors in rats experimental models of hypertension, renal failure and heart failurePrincipal Investigator
- Principal Investigator
  
  YASUJIMA Minoru
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tohoku University

All 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book

[Book] 高血圧(下)(日本臨床67巻増刊号7)(【高血圧(第4版) 日本における最新の研究動向】臨床編臓器障害進展予測検査の進歩 BNP)2009
- Author(s)
  庄司優、保嶋実
- Publisher
  株式会社日本臨床社
- Data Source
  KAKENHI-PROJECT-19590546
[Book] 高血圧(上)(日本臨床67巻増刊号6)(【高血圧(第4版) 日本における最新の研究動向】基礎編循環生理活性物質の最新知見血管作動性物質生合成、分泌、生理作用バソプレシン)2009
- Author(s)
  庄司優、保嶋実
- Publisher
  株式会社日本臨床社
- Data Source
  KAKENHI-PROJECT-19590546
[Book] 日本臨床67巻増刊号7高血圧 (下)【高血圧 (第4版) 日本における最新の研究動向】臨床編臓器障害進展予測検査の進歩BNP2009
- Author(s)
  庄司優, 保嶋実
- Publisher
  株式会社日本臨床社
- Data Source
  KAKENHI-PROJECT-19590546
[Book] 日本臨床67巻増刊号6高血圧 (上)【高血圧 (第4版) 日本における最新の研究動向】基礎編循環生理活性物質の最新知見血管作動性物質生合成、分泌、生理作用バソプレシン20092009
- Author(s)
  庄司優, 保嶋実
- Publisher
  株式会社日本臨床社
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] Olmesartan ameliorates peripheral nerve dysfunction in Zucker diabetic fatty rats2011
- Author(s)
  K. Sugimoto, K. Kojima, M. Babab, M Yasujima
- Journal Title
  
  J Hypertens
  
  Volume: 29(7) Pages: 1337-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590609
[Journal Article] Mutational analysis of SLC12A3 gene in a Japanese general population of northern Japan2011
- Author(s)
  Tsutaya S, Sugimoto K, Nakaji S, Yasujima M
- Journal Title
  
  Hirosaki Med J 62巻(印刷中)
- NAID
  110008735852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] 弘前大学医学部附属病院における医療支援部門としての検査の現状と課題2011
- Author(s)
  杉本一博、齋藤慶子、小島佳也、蔦谷昭司、保嶋実
- Journal Title
  
  臨床病理
  
  Volume: 59(9) Pages: 870-878
- Data Source
  KAKENHI-PROJECT-21590609
[Journal Article] 弘大病院中央採血室におけるトラブルについて2010
- Author(s)
  斉藤順子、井上文緒、小島佳也、杉本一博、保嶋実
- Journal Title
  
  臨床病理
  
  Volume: 58(6) Pages: 577-580
- NAID
  10027751659
- Data Source
  KAKENHI-PROJECT-21590609
[Journal Article] Quantification of cystatin C in cerebrospinal fluid from various neurological disorders and correlation with G73A polymorphism in CST32010
- Author(s)
  Y. Yamamoto-Watanabe, M. Watanabe, M. Jackson, H. Akimoto, K. Sugimoto, M. Yasujima, Y. Wakasaya, E. Matsubara, T. Kawarabayashi, Y. Harigaya, A.R. Lyndon, M. Shoji
- Journal Title
  
  Brain Res
  
  Volume: 1361 Pages: 140-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590609
[Journal Article] Gitelman症候群の診断と病態解析2010
- Author(s)
  蔦谷昭司、澤田知香、小山有希、中田良子、對馬絵理子、杉本一博、保嶋実
- Journal Title
  
  臨床病理
  
  Volume: 58(12) Pages: 1219-1220
- NAID
  10029426720
- Data Source
  KAKENHI-PROJECT-21590609
[Journal Article] 生理検査室におけるインシデント分析2010
- Author(s)
  四釜佳子、原悦子、齋藤慶子、杉本一博、保嶋実
- Journal Title
  
  臨床病理
  
  Volume: 58(12) Pages: 1233-1233
- NAID
  10029426732
- Data Source
  KAKENHI-PROJECT-21590609
[Journal Article] 弘前大学医学部医学科における臨床検査医学教育の現状と課題:なぜ、誰が教育するのか?なぜ、誰が教育するのか?2010
- Author(s)
  杉本一博、保嶋実
- Journal Title
  
  臨床病理
  
  Volume: 58(3) Pages: 267-274
- Data Source
  KAKENHI-PROJECT-21590609
[Journal Article] サイアザイド感受性Na-Cl共輸送体 (SLC12A3) 遺伝子異常による低K血症2009
- Author(s)
  保嶋実, 蔦谷昭司
- Journal Title
  
  BIO Clinica 24
  
  Pages: 927-931
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] サイアザイド感受性Na-Cl共輸送体(SLC12A3)遺伝子異常による低K血症2009
- Author(s)
  保嶋実, 蔦谷昭司
- Journal Title
  
  BIO Clinica 24
  
  Pages: 927-931
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] 地域住民におけるサイアザイド感受性Na-Cl共輸送体(SLC12A3)遺伝子変異頻度について-岩木町健康増進プロジェクト2009
- Author(s)
  保嶋実, 蔦谷昭司
- Journal Title
  
  臨床病理 57
  
  Pages: 391-396
- NAID
  10025224870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article]2009
- Author(s)
  庄司優, 保嶋実
- Journal Title
  
  日本臨床67巻増刊号6高血圧(上)【高血圧(第4版)日本における最新の研究動向】基礎編循環生理活性物質の最新知見血管作動性物質生合成、分泌、生理作用バソプレシン(株式会社日本臨床社)
  
  Pages: 212-215
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] サイアザイド感受性Na-Cl共輸送体(SLC12A3)遺伝子異常による低K血症2009
- Author(s)
  保嶋実、蔦谷昭司
- Journal Title
  
  BIO Clinica 24巻
  
  Pages: 927-931
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] 地域住民におけるサイアザイド感受性Na-Cl共輸送体(SLC12A3)遺伝子変異頻度について-岩木町健康増進プロジェクト2009
- Author(s)
  保嶋実、蔦谷昭司
- Journal Title
  
  臨床病理 57巻
  
  Pages: 391-396
- NAID
  10025224870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article]2009
- Author(s)
  庄司優, 保嶋実
- Journal Title
  
  日本臨床67巻増刊号7高血圧(下)【高血圧(第4版)日本における最新の研究動向】臨床編臓器障害進展予測検査の進歩BNP(株式会社日本臨床社)
  
  Pages: 187-190
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] 地域住民におけるサイアザイド感受性Na-Cl共輸送体 (SLC12A3) 遺伝子変異頻度について-岩木町健康増進プロジェクト2009
- Author(s)
  保嶋実, 蔦谷昭司
- Journal Title
  
  臨床病理 57
  
  Pages: 391-396
- NAID
  10025224870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] Role of advanced glycation end products in diabetic neuropathy2008
- Author(s)
  Sugimoto K, Yasujima M, Yagihashi S
- Journal Title
  
  Curr Pharm Des 14
  
  Pages: 953-961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] 尿細管機能検査およびGitelman症候群における遺伝子変異解析の有用性について2008
- Author(s)
  島田美智子, 保嶋実
- Journal Title
  
  臨床化学 37
  
  Pages: 29-34
- NAID
  130003357313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] 尿細管機能検査および Gitelman 症候群における遺伝子変異解析の有用性について2008
- Author(s)
  島田美智子, 保嶋実
- Journal Title
  
  臨床化学 37
  
  Pages: 29-34
- NAID
  130003357313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] 尿細管機能検査およびGitelman症候群における遺伝子変異解析の有用性について2008
- Author(s)
  島田美智子、保嶋実
- Journal Title
  
  臨床化学 37巻
  
  Pages: 29-34
- NAID
  130003357313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] Role of advanced glycation end products in diabetic neuropathy2008
- Author(s)
  Sugimoto K, Yasujima M, Yagihashi S
- Journal Title
  
  Curr Pharm Des 14巻
  
  Pages: 953-961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] サイアザイド感受性NaCl共輸送体遺伝子解析の臨床的意義2007
- Author(s)
  保嶋実
- Journal Title
  
  臨床病理 55
  
  Pages: 338-343
- NAID
  10019569535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] 二次性高血圧スクリーニングのための臨床検査2007
- Author(s)
  保嶋実
- Journal Title
  
  日本臨床検査自動化学会会誌 32
  
  Pages: 129-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] Role of vasopressin Vla receptor in hypertension, diabetes mellitus and platelet functions : genetic polymorphism study.2007
- Author(s)
  Hasan KN, Shoji M, Sugimoto K, Tsutaya S, Yasujima M.
- Journal Title
  
  Hirosaki Med J 58
  
  Pages: 35-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590482
[Journal Article] サイアザイド感受性NaCl共輸送体遺伝子解析の臨床的意義2007
- Author(s)
  保嶋実
- Journal Title
  
  臨床病理 55巻
  
  Pages: 338-343
- NAID
  10019569535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] 内分泌疾患の検査診断法の進歩心血管系疾患におけるバゾプレシン研究の進展2007
- Author(s)
  庄司優, 保嶋実
- Journal Title
  
  臨床病理 55
  
  Pages: 544-548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] サイアザイド感受性NaCl共輸送体遺伝子解析の臨床的意義2007
- Author(s)
  保嶋実
- Journal Title
  
  臨床病理 55
  
  Pages: 338-343
- NAID
  10019569535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590546
[Journal Article] Gene analysis of the calcium channel 1 subunit and clinical studies for two patients with hypokalemic periodic paralysis.2006
- Author(s)
  Kageyama K, Terui K, Tsutaya S, Matsuda E, Shoji M, Sakihara S, Nigawara T, Takayasu S, Moriyama T, Yasujima M, Suda T.
- Journal Title
  
  J Endocrinol Invest 29
  
  Pages: 928-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590482
[Journal Article] A novel mutation of the thiazide-sensitive sodium chloride cotransporter gene in a Japanese family with Gitelman syndrome.2006
- Author(s)
  Terui K, Shoji M, Yamashiki J, Hirai Y, Ishiguro A, Tsutaya S, Kageyama K, Yasujima M, Suda T.
- Journal Title
  
  Clin Nephrol 65
  
  Pages: 57-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590482
[Journal Article] Study of Vla vasopressin receptor gene single nucleotide polymorphisms in platelet vasopressin responsiveness.2006
- Author(s)
  Hasan KN, Shoji M, Tsutaya S, Kudo R., Matsuda E, Saito J, Kimura T, Yasujima M.
- Journal Title
  
  J Clin Lab Anal 20
  
  Pages: 87-92
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590482
[Journal Article] 高血圧-最新の研究動向- : BNP2006
- Author(s)
  庄司優, 保嶋実
- Journal Title
  
  日本臨床 64・増6
  
  Pages: 133-136
- Data Source
  KAKENHI-PROJECT-17590482
[Journal Article] 高血圧-最新の研究動向- : 血管内皮型NO合成酵素遺伝子2006
- Author(s)
  庄司優, 保嶋実
- Journal Title
  
  日本臨床 64・増5
  
  Pages: 411-415
- Data Source
  KAKENHI-PROJECT-17590482
[Journal Article] バソプレシン遺伝子発現と分泌調節2005
- Author(s)
  庄司優, 木村時久, 保嶋実
- Journal Title
  
  日本臨床 63・増5
  
  Pages: 460-465
- Data Source
  KAKENHI-PROJECT-15590477
[Journal Article] DPCと遺伝子検査2005
- Author(s)
  庄司優, 保嶋実
- Journal Title
  
  臨床病理 52
  
  Pages: 1007-1010
- NAID
  10014294717
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] Diagnosis of a case of Gitelman's syndrome based on renal clearance studies and gene analysis of a novel mutation of the thiazide-sensitive Na-Cl cotransporter.2005
- Author(s)
  Kageyama K, Terui K, Shoji M, Tsutaya S, Matsuda E, Sakihara S, Nigawara T, Moriyama T, Yasujima M, Suda T.
- Journal Title
  
  J Endocrinol Invest 28
  
  Pages: 822-626
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590482
[Journal Article] 疾患群の遺伝学的検査と遺伝子検査:腎・血管疾患2005
- Author(s)
  庄司優, 保嶋実
- Journal Title
  
  日本臨床 63・増12
  
  Pages: 223-227
- Data Source
  KAKENHI-PROJECT-17590482
[Journal Article] DPCと遺伝子検査2005
- Author(s)
  庄司優, 保嶋実
- Journal Title
  
  臨床病理 52
  
  Pages: 1007-1010
- NAID
  10014294717
- Data Source
  KAKENHI-PROJECT-15590477
[Journal Article] バソプレシン遺伝子発現と分泌調節2005
- Author(s)
  庄司優, 木村時久, 保嶋実
- Journal Title
  
  日本臨床 63・増5
  
  Pages: 460-465
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] Hypertension in a patient with Gitelman's syndrome.2004
- Author(s)
  Ogihara T, Katsuya T, Ishikawa K, Matsuo A, Rakugi H, Shoji M, Yasujima M
- Journal Title
  
  J Hum Hypertens 18
  
  Pages: 677-679
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] 血小板第4因子、β-トロンボグロブリン2004
- Author(s)
  庄司優, 保嶋実
- Journal Title
  
  血栓と循環 12
  
  Pages: 336-338
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] ウロテンシン:血小板作用2004
- Author(s)
  庄司優, 須田俊宏, 保嶋実
- Journal Title
  
  日本臨床 62・増9
  
  Pages: 715-718
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] ウロテンシン:血小板作用2004
- Author(s)
  庄司優, 須田俊宏, 保嶋実
- Journal Title
  
  日本臨床 62・増9
  
  Pages: 715-718
- Data Source
  KAKENHI-PROJECT-15590477
[Journal Article] Peripheral nerve endoneurial microangiopathy and necrosis in rats with insulinoma.2004
- Author(s)
  Sugimoto K, Shoji M, Yasujima M, Suda T, Yagihashi S
- Journal Title
  
  Acta Neuropathol (Berl) 108
  
  Pages: 503-514
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] 高血圧における遺伝子マーカー2003
- Author(s)
  保嶋実, 他
- Journal Title
  
  臨床化学 32・1
  
  Pages: 46-48
- NAID
  10011472006
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590477
[Journal Article] 我が国における高血圧診療のガイドライン2003
- Author(s)
  保嶋実
- Journal Title
  
  臨床病理 51・6
  
  Pages: 581-585
- NAID
  10011470805
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590477
[Journal Article] Lack of association of 4G/5G-polymorphism in plasminogen activator inhibitor-1 gene Cardiovascular Disorders and with stroke.2003
- Author(s)
  Shoji M, Yasujima M
- Journal Title
  
  Advances in Brain Research Neurodegeneration (Elsevier Sciences)
  
  Pages: 105-109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] Guidelines for the management of hypertension in Japan2003
- Author(s)
  Yasujima M
- Journal Title
  
  Rinsho Byori. 51-6
  
  Pages: 581-585
- NAID
  10011470805
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590477
[Journal Article] Genetic markers for hypertensive disorders2003
- Author(s)
  Yasujima M, et al.
- Journal Title
  
  Jpn J Clin Chem 32-1
  
  Pages: 46-48
- NAID
  10011472006
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590477
[Journal Article] 連関解析におけるSNPsの有用性:高血圧におけるミトコンドリア膿移型の意義2002
- Author(s)
  庄司優, 保嶋実, 他
- Journal Title
  
  臨床病理 50
  
  Pages: 497-501
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] Lack of association between Y chromosome Alu insertion polymorphism and hypertension2002
- Author(s)
  Shoji M, Yasujima M, et al.
- Journal Title
  
  Hypertension Research 25
  
  Pages: 1-3
- NAID
  50001041938
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] Lack of association between Y chromosome Alu insertion polymorphism and hypertension.2002
- Author(s)
  Shoji M, Tsutaya S, Shimoda J, Kojima K, Kasai T, Yasujima M
- Journal Title
  
  Hypertens Res 25
  
  Pages: 1-3
- NAID
  50001041938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] 臨床に有用な遺伝子検査:IV.遺伝性疾患 4.腎・血管疾患2002
- Author(s)
  庄司優, 保嶋実
- Journal Title
  
  臨床病理レビュー 123
  
  Pages: 184-190
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13672412
[Journal Article] Association of novel promoter single nucleotide polymorphisms in vasopressin Vla receptor gene with essential hypertension in nonobese Japanese.
- Author(s)
  Hasan KN, Shoji M, Sugimoto K, Tsutaya S, Matsuda E, Kudo R, Nakaji S, Suda T, Yasujima M.
- Journal Title
  
  J Human Hypertension (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590482
[Journal Article] A diagnosis on the case of Gitelman's syndrome by renal clearance studies and the gene analysis with a novel mutation of the thiazide-sensitive Na-Cl cotransporter.
- Author(s)
  Kageyama K, Terui K, Tsutaya S, Shoji M, Sakihara S, Nigawara T, Moriyama T, Yasujima M, Suda T
- Journal Title
  
  J Endocrinol Invest (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672412
[Presentation] 日常的な糖尿病性神経障害の検査法と皮膚生検による表皮内神経線維密度との関連性2011
- Author(s)
  村上宏、杉本一博、村上洋、山下真紀、松木恒太、田辺壽太郎、松井淳、玉澤直樹、保嶋実、八木橋操六、須田俊宏
- Organizer
  第54回日本糖尿病学会年次学術集
- Place of Presentation
  札幌プリンスホテル
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] 高血圧におけるサイアザイド感受性Na-Cl共輸送体(SLC12A3)遺伝子のプロモーター領域多型の検討2011
- Author(s)
  蔦谷昭司、杉本一博、保嶋実
- Organizer
  第58回日本臨床検査医学会学術集会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] Low-dose insulin deactivates p44/42 MAPK and ameliorates peripheral sensory nerve dysfunction in rats with streptozotocin-induced diabetes2011
- Author(s)
  Sugimoto K, Baba M, Yagihashi S, Yasujima M
- Organizer
  71th Scientific sessions of the American Diabetes Association
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] 血糖値に影響を与えない少量のインスリン投与がストレプトゾトシン誘発糖尿病ラットの末梢神経インスリンシグナルに与える影響2011
- Author(s)
  杉本一博、馬場正之、八木橋操六、保嶋実
- Organizer
  第54回日本糖尿病学会年次学術集
- Place of Presentation
  札幌プリンスホテル
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] 少量インスリン持続投与が非糖尿病ウィスターラットの末梢神経機能および形態に及ぼす影響2010
- Author(s)
  杉本一博、小島佳也、保嶋実
- Organizer
  第57回日本臨床検査医学会学術集会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] 糖尿病腎症におけるサイアザイド感受性Na-Cl共輸送体(SLC12A3)遺伝子のプロモーター領域多型の検討2010
- Author(s)
  蔦谷昭司、杉本一博、保嶋実
- Organizer
  第57回日本臨床検査医学会学術集会
- Place of Presentation
  東京都新宿区
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] Effects of long-term administration of moderate amounts of insulin on small and large peripheral nerve fiber function and structure in non-diabetic Wistar rats2010
- Author(s)
  K. Sugimoto, K. Kojima, M.Baba, M. Yasujima
- Organizer
  46th Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] 長期間の少量インスリン投与が非糖尿病ウィスターラットの末梢神経機能に与える影響2010
- Author(s)
  杉本一博、八木橋操六、馬場正之、保嶋実
- Organizer
  第24回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  ホテルコスモスクエア国際交流センター
- Year and Date
  2010-01-23
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] 7ヶ月間の少量インスリン持続投与が非糖尿病ウィスターラットの痛覚反応および神経伝導速度に与える影響2010
- Author(s)
  杉本一博、八木橋操六、馬場正之、保嶋実
- Organizer
  第53回日本糖尿病学会年次学術集
- Place of Presentation
  山全日空ホテル
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] ELMO1およびELMO2遺伝子多型と推算糸球体濾過量に関する検討2010
- Author(s)
  蔦谷昭司, 保嶋実
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] R904Q variant in the SLC12A3 is associated with bone mineral density in Japanese women2010
- Author(s)
  Tsutaya S, Sugimoto K, Yasujima M
- Organizer
  23th Scientific Meeting International Society of Hypertension
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-30
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] シンポジウム「検査部のあり方と将来展望」弘前大学医学部附属病院における医療支援部門としての検査部の現状と課題2010
- Author(s)
  杉本一博、齋藤慶子、小島佳也、蔦谷昭司、保嶋実
- Organizer
  第34回日本臨床検査医学会東北支部例会
- Place of Presentation
  コラッセふくしま
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] T180K variant in the SLC12A3 is associated with impaired glucose tolerance in a Japanese population2009
- Author(s)
  Tsutaya S, Sugimoto K, Yasujima M
- Organizer
  The Iwaki Health Promotion Project. World Congress of Nephrology 2009
- Place of Presentation
  Milan, Italy
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] Effects of Treatment with Angiotensin II Type-1 Receptor Blocker on Peripheral Nerve Dysfunction in Zucker Diabetic Fatty Rats2009
- Author(s)
  Sugimoto K, Yasujima M
- Organizer
  69th Scientific sessions of the American Diabetes Association
- Place of Presentation
  New Orlenans, USA
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] T180K variant in the SLC12A3 is associated with impaired glucose tolerance in a Japanese population. The Iwaki Health Promotion Project.2009
- Author(s)
  Tsutaya S, Sugimoto K, Yasujima M
- Organizer
  World Congress of Nephrology 2009
- Place of Presentation
  Milan, Italy
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] Angiotensin II type-1 receptor blocker olmesartan increases neuronal expression of angiotensin II receptors in dorsal root ganglia and ameliorates diabetic peripheral neuropathy in Zucker diabetic fatty rats2009
- Author(s)
  Sugimoto K, Baba M, Yasujima M
- Organizer
  45th Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] ピオグリタゾンは2型糖尿病ZDFラットモデルの痛覚異常を改善する2009
- Author(s)
  杉本一博、小島佳也、保嶋実
- Organizer
  第56回日本臨床検査医学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] シンポジウム「医学教育における臨床検査医学の重要性とその貢献」弘前大学医学部医学科における臨床検査医学教育の現状と課題2009
- Author(s)
  杉本一博、保嶋実
- Organizer
  第33回日本臨床検査医学会東北支部例会
- Place of Presentation
  フォレスト仙台
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] アンジオテンシンII1型受容体拮抗薬オルメサルタンの2型糖尿病ZDFラット末梢神経障害に対する投与効果2009
- Author(s)
  杉本一博、保嶋実
- Organizer
  第52回日本糖尿病学会年次学術集
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21590609
[Presentation] アンジオテンシンII1型受容体拮抗薬オルメサルタンの2型糖尿病ZDFラットの末梢神経障害に対する投与効果2009
- Author(s)
  杉本一博, 保嶋実
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] 地域住民におけるサイアザイド感受性Na-Cl共輸送体(SLC12A3)の遺伝子変異検出頻度について2008
- Author(s)
  蔦谷昭司, 保嶋実
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2008-05-31
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] Mutational analysis of SLC12A3 gene in 43 patients with Gitelman's syndrome.2008
- Author(s)
  Tsutaya S, Yasujima M
- Organizer
  22th Scientific Meeting International Society of Hypertension
- Place of Presentation
  Berlin, Germany
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] 血圧異常と低K血症におけるサイアザイド感受性Na-Cl共輸送体(SLC12A3)遺伝子解析の意義2008
- Author(s)
  保嶋実, 蔦谷昭司
- Organizer
  第15回日本遺伝子診療学会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2008-08-01
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] 糖尿病性腎症におけるサイアザイド感受性Na-Cl共輸送体(SLC12A3)の遺伝子変異に関する検討2008
- Author(s)
  蔦谷昭司、小野有希、杉本一博、保嶋実
- Organizer
  第55回日本臨床検査医学会学術集会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] Mutational analysis of SLC12A3 gene in a Japanese population with hypokalemia2008
- Author(s)
  Tsutaya S, Yasujima M
- Organizer
  22th Scientific Meeting International Society of Hypertension
- Place of Presentation
  Berlin, Germany
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] 糖尿病性腎症におけるサイアザイド感受性Na-Cl共輸送体 (SILC12A3) の遺伝子変異に関する検討2008
- Author(s)
  蔦谷昭司, 小野有希, 杉本一博, 保嶋実
- Organizer
  第55回日本臨床検査医学会学術集会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] サイアザイド感受性Na-Cl共輸送体(SLC12A3)遺伝子解析の臨床的意義2008
- Author(s)
  保嶋実
- Organizer
  第42回日本臨床検査医学会北海道支部総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] 高血圧とサイアザイド感受性Na-Cl共輸送体(SLC12A3)の遺伝子多型との連関について2008
- Author(s)
  蔦谷昭司, 保嶋実
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] Mutational analysis of SLC12A3 gene in a Japanese population with hypo- kalemia2008
- Author(s)
  Tsutaya S, Yasujima M
- Organizer
  22th Scientific Meeting Inter- national Society of Hypertension
- Place of Presentation
  Berlin, Germany
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] Mutational analysis of SLC12A3 gene in 43 patients with Gitelman's syndrome2008
- Author(s)
  Tsutaya S, Yasujima M
- Organizer
  22th Scientific Meeting International Society of Hypertension
- Place of Presentation
  Berlin, Germany
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] 一般住民におけるサイアザイド感受性Na-Cl共輸送体(SLC12A3)の遺伝子変異検出頻度に関する検討2007
- Author(s)
  蔦谷昭司、小野有希、保嶋実
- Organizer
  第54回日本臨床検査医学会学術集会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2007-11-24
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] 現在の腎機能検査は腎障害をどこまで正しく評価できるか-尿細管機能検査2007
- Author(s)
  保嶋実
- Organizer
  第26回日本臨床化学会夏期セミナー
- Place of Presentation
  三重県志摩市
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] 一般住民におけるサイアザイド感受性Na-Cl共輸送体 (SLC12A3) の遺伝子変異検出頻度に関する検討2007
- Author(s)
  蔦谷昭司, 小野有希, 保嶋実
- Organizer
  第54回日本臨床検査医学会学術集会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2007-11-24
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] 高血圧と血液凝固関連諸因子の遺伝子多型に関する検討2007
- Author(s)
  蔦谷昭司, 保嶋実
- Organizer
  第30回日本高血圧学会総会
- Place of Presentation
  沖縄県宜野湾市
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19590546
[Presentation] 低カリウム血症におけるサイアザイド感受性Na-Cl共輸送体(SLC12A3)の遺伝子変異検出頻度に関する検討2007
- Author(s)
  蔦谷昭司, 保嶋実
- Organizer
  第30回日本高血圧学会総会
- Place of Presentation
  沖縄県宜野湾市
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19590546

1. SHOJI Masaru (10226300)

# of Collaborated Projects: 9 results

# of Collaborated Products: 31 results
2. KOHZUKI Masahiro (70234698)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. SUGIMOTO Kazuhiro (70271799)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
4. ABE Keishi (60004777)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 竹内和久 (40260426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TSUNODA Kazuo (50217361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KUDO Kei (00214966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KONNO Tasuke (00004846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MINEGISHI Masayoshi (20211592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SATO Tetsuo (90170761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TSUCHIYA Sigeru (30124605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 大沢弘 (80223791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 尾股健 (50194634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 佐藤牧人 (90201532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 寺沢政彦 (80192201)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TSUTAYA Shoji

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
17. OYAMA Yuuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAKATA Ryoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SAWADA Chika

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YAMAGUTI Yosiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YASUJIMA Minoru 保嶋 実

土屋 滋

久嶋 実

Research Projects

Research Products

Co-Researchers

Elucidation of time course and molecular mechanism of intraepidermal nerve fiber loss in diabetic polyneuropathy

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Clinical significance of SLC12A3 gene polymorphisms in diabetic nephropathyPrincipal Investigator

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Molecular and pathogenic mechanisms for peripheral neuropathy associated with metabolic syndrome

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Molecular analysis of heterogeneity in human platelet aggregation response

Principal Investigator

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Clinical Significance of Sodium Metabolism-related Gene Polymorphisms in Salt-Sensitive HypertensionPrincipal Investigator

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Ethnic differences in genetic markers for hypertension in the two major lineages of modern Japanese, Jomon and Yayoi

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The significance of endothelial nitric oxide synthase gene polymorphisms as genetic markers of hypertensive disordersPrincipal Investigator

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ナトリウム代謝感受性遺伝子多型および変異の検査同定法の確立とその臨床応用Principal Investigator

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Pathological Significance of Gene Polymorphisms of the Renin-Angiotensin System in Hypertension.Principal Investigator

Principal Investigator

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The role of tissue renin-angiotensin system on cardiovascular and renal hypertrophy/hyperplasia

Principal Investigator

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Characterization, localization and quantification of neutral metalloendopeptidase, the degradative enzyme for atrial natriuretic peptidePrincipal Investigator

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Regulatory Mechanism of Biosynthesis and Cellular Action of Renal Vasoactive Hormones.

Principal Investigator

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Anti-human LFA-1 monoclonal antibodies for prevention of graft failure in HLA-mismatched bone marrow transplantation.

Principal Investigator

YASUJIMA Minoru 保嶋実

土屋滋

久嶋実

[Book] 高血圧(下)(日本臨床67巻増刊号7)(【高血圧(第4版) 日本における最新の研究動向】臨床編臓器障害進展予測検査の進歩 BNP)2009

[Book] 高血圧(上)(日本臨床67巻増刊号6)(【高血圧(第4版) 日本における最新の研究動向】基礎編循環生理活性物質の最新知見血管作動性物質生合成、分泌、生理作用バソプレシン)2009

[Book] 日本臨床67巻増刊号7高血圧 (下)【高血圧 (第4版) 日本における最新の研究動向】臨床編臓器障害進展予測検査の進歩BNP2009

[Book] 日本臨床67巻増刊号6高血圧 (上)【高血圧 (第4版) 日本における最新の研究動向】基礎編循環生理活性物質の最新知見血管作動性物質生合成、分泌、生理作用バソプレシン20092009