• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Ochiai Masako  落合 雅子

ORCIDConnect your ORCID iD *help
… Alternative Names

OCHIAI Masako  落合 雅子

落合 雅子

Less
Researcher Number 90150200
Other IDs
Affiliation (based on the past Project Information) *help 2016: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員
2015 – 2016: 国立研究開発法人国立がん研究センター, その他部局等, 研究員
2015: 国立研究開発法人国立がん研究センター, 研究所動物実験部門, 主任研究員
2014: 独立行政法人国立がん研究センター, その他部局等, 研究員
2007: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, Biochemistry Division, Staff Scientist … More
2005 – 2007: 国立がんセンター(研究所及び東病院臨床開発センター), 生化学部, 主任研究官
2005: National Cancer Center (Research Institute), Research Institute, Biochemistry Division, Staff, 研究所生化学部, 主任研究官
2004: Biochemistry Div., National Cancer Center Eesearch Institute, Staff, 主任研究官
2004: 国立がんセンター(研究所), 生化学部, 主任研究官
2004: 国立がんセンター(研究所), 研究所・生化学部, 主任研究官
2003: 国立がんセンター研究所, 生化学部, 主任研究員
2000 – 2003: 国立がんセンター, 研究所・生化学部, 主任研究官
1987: 国立がんセンター研究所, 発がん研究部, 研究員 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Tumor biology
Except Principal Investigator
Biological Sciences / Tumor biology
Keywords
Principal Investigator
aberrant crypt foci / haploid insufficiency / azoxymethane / de novo colorectal cancer / early lesions of colon cancer / de novo癌 / 大腸がん初期病変 / gpt delta mouse / DNA-PKcs mutation / colon carcinogenesis … More / DNA repair through non-homologous end-joining (NHEJ) pathway / gpt deltaマウス / DNA-PKcs変異 / 大腸発がん / haploidinsufficiency / 非相同末端再結合(NHEJ)修復 / in vitro肺発がんモデル / 正常肺3D培養 … More
Except Principal Investigator
PhIP / mutation spectrum / animal model / dysplastic ACF / HCA / 大腸がん / AOM / gene expression analysis / hierarchical gene clustering analysis / colon carcinogensies / β-catenin / methylation / Apc / Colon carcinogenesis / heterocyclic amines / gene expression profile / HCAs / cancer susceptibility / Dysplastic ACF / ACF / ラット / 発がん予防 / 発がん要因 / colon carcinogenesis / 変異スペクトラム / 遺伝子発現解析 / 階層型クラスター解析 / colon carcinoenesis / 大腸がんモデル / PhIp / 2ーアミノー3ーメチルイミダゾ〔4,5ーf〕キノリン / 加熱食品 / がん / アテローム斑 / 幹細胞 / モデル / 大腸 / 癌 / 3次元培養 / オルガノイド / 発がん / オリゴ-CGHアレイ / BAC-CGHアレイ / copy number aberration / ゲノム解析 / 大腸炎 Less
  • Research Projects

    (7 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (7 People)
  •  Elucidation of molecular mechanisms underlying colon carcinogenesis and discovery of therapeutic targets by using a novel in vitro model

    • Principal Investigator
      Hippo Yoshitaka
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Lung carcinogenesis by genetic reconstitution using organoids derived from normal lung in micePrincipal Investigator

    • Principal Investigator
      Ochiai Masako
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      National Cancer Center Japan
  •  Elucidation of the genesis mechanism of early lesions of colon cancer-Toward the elucidation of early lesions of de novo colorectal ceancer in humansPrincipal Investigator

    • Principal Investigator
      OCHIAI Masako
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  環境因子による大腸発がんモデルを用いたがんの浸潤性進展過程のゲノム網羅的解析

    • Principal Investigator
      NAKAGAMA Hitoshi
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Haploid insufficiency in DNA repair through non-homologous end-joining pathway and its effect on colon carcinogenesisPrincipal Investigator

    • Principal Investigator
      OCHIAI Masako
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      National Cancer Center (Research Institute)
  •  Specificity of mutation spectrum and gene expression profiles induced by environmental carcinogens

    • Principal Investigator
      NAKAGAMA Hitoshi
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute
  •  環境中の動脈硬化原ーがん原物質の検索及びその作用機構の解明

    • Principal Investigator
      若林 敬二
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2019 2017 2016 2015 2014 2007 2005 2003 2001 Other

All Journal Article Presentation

  • [Journal Article] Kras-driven heterotopic tumor development from hepatobiliary organoids2019

    • Author(s)
      Ochiai Masako、Yoshihara Yasunori、Maru Yoshiaki、Matsuura Tetsuya、Izumiya Masashi、Imai Toshio、Hippo Yoshitaka
    • Journal Title

      Carcinogenesis

      Volume: 印刷中 Pages: 1142-1152

    • DOI

      10.1093/carcin/bgz024

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08755, KAKENHI-PROJECT-18K07932, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-18K16823, KAKENHI-PROJECT-26430134
  • [Journal Article] Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation.2017

    • Author(s)
      Kangawa Y, Yoshida T, Maruyama K, Okamoto M, Kihara T, Nakamura M, Ochiai M, Hippo Y, Hayashi SM, Shibutani M.
    • Journal Title

      Food Chem Toxicol

      Volume: 100 Pages: 103-114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Journal Article] Newly defined aberrant crypt foci as a marker for dysplasia in the rat colon.2014

    • Author(s)
      Ochiai M, Hippo Y, Izumiya M, Watanabe M, Nakagama H.
    • Journal Title

      Cancer Science

      Volume: 105 Issue: 8 Pages: 943-950

    • DOI

      10.1111/cas.12446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590710
  • [Journal Article] Differential staining of dysplastic aberrant crypt foci in the colon facilitates prediction of carcinogenic potentials of chemicals in rats.2005

    • Author(s)
      Ochiai M, et a1.
    • Journal Title

      Cancer Lett 220

      Pages: 67-74

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213151
  • [Journal Article] Differential staining of dysplastic aberrant crypt foci in the colon facilitates prediction of carcinogenic potentials of chemicals in rats2005

    • Author(s)
      Ochiai M, et al.
    • Journal Title

      Cancer Letters 220

      Pages: 67-74

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12213151
  • [Journal Article] Differential staining of dysplastic aberrant crypt foci in the colon facilitates prediction of carcinogenic potentials of chemicals in rats2005

    • Author(s)
      Ochiai M, et al.
    • Journal Title

      Cancer Letters 220

      Pages: 67-74

    • Data Source
      KAKENHI-PROJECT-17013092
  • [Journal Article] Differential staining of dysplastic aberrant crypt foci in the colon facilitates prediction of carcinogenic potentials of chemicals in rats.2005

    • Author(s)
      Ochiai M, Nakagama H, et al.
    • Journal Title

      Cancer Letters 220

      Pages: 67-74

    • Data Source
      KAKENHI-PROJECT-12213151
  • [Journal Article] Characterization of aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6- phenylimidazo[4,5-6]pyridine, PhIP.2003

    • Author(s)
      Ochiai M, et al.
    • Journal Title

      Am. J. Pathol 163

      Pages: 1607-1614

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213151
  • [Journal Article] Characterization of aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, PhIP2003

    • Author(s)
      Ochiai M, et al.
    • Journal Title

      American Journal of Pathology 163

      Pages: 1607-1614

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12213151
  • [Journal Article] High susceptibility of Scid mice to colon carcinogenesis induced by azoxymethane indicates a possible caretaker role for DNA-dependent protein kinase2001

    • Author(s)
      Ochiai M, et al.
    • Journal Title

      Carcinogenesis 22

      Pages: 1551-1555

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12213151
  • [Journal Article] High susceptibility of Scid mice to colon carcinogenesis induced by azoxymethane indicates a possible caretaker role for DNA-dependent protein kinase.2001

    • Author(s)
      Ochiai M, et al.
    • Journal Title

      Carcinogenesis 22

      Pages: 1551-1555

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213151
  • [Presentation] in vitroモデルが明らかにするマウス膵管発がんにおけるKras遺伝子材の重要性2016

    • Author(s)
      松浦哲也、落合雅子、中島淳、今井俊夫、筆宝義隆
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] オルガノイドを用いた胆嚢発がんモデルの確立2016

    • Author(s)
      筆宝義隆、丸喜明、落合雅子、松浦哲也、今井俊夫
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] オルガノイドを用いた卵巣がんモデルの開発2016

    • Author(s)
      丸喜明、落合雅子、今井俊夫、筆宝義隆
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス正常大腸上皮細胞の3次元培養によるin vitro発がんモデルの開発―化学発がん・予防研究への応用に向けて2016

    • Author(s)
      落合雅子、松浦哲也、筆宝義隆、今井俊夫
    • Organizer
      がん予防学術大会2016名古屋
    • Place of Presentation
      愛知県・名古屋市
    • Year and Date
      2016-07-01
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] マウス正常大腸上皮細胞の3次元培養によるin vitro発がんモデルの開発2016

    • Author(s)
      落合雅子、松浦哲也、中釜斉、筆宝義隆、今井俊夫.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス正常大腸上皮細胞の3次元培養によるin vitro発がんモデルの開発2016

    • Author(s)
      落合雅子、松浦哲也、中釜斉、筆宝義隆、今井俊夫
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      神奈川県・横浜市
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] マウス正常大腸上皮細胞の3次元培養によるin vitro発がんモデルの開発―化学発がん・予防研究への応用に向けて2016

    • Author(s)
      落合雅子、松浦哲也、筆宝義隆、今井俊夫
    • Organizer
      がん予防学術大会2016
    • Place of Presentation
      名古屋
    • Year and Date
      2016-07-01
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス正常腸管上皮の3次元培養法を用いる発がん再構成系に対するPhIPの修飾作用2015

    • Author(s)
      落合雅子、松浦哲也、中釜 斉、筆宝義隆、今井俊夫
    • Organizer
      第30回発癌病理研究会
    • Place of Presentation
      香川県小豆郡土庄町
    • Year and Date
      2015-08-26
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] 正常上皮細胞の3次元培養によるin vitro発がんモデルの開発 -化学発がん・予防研究への応用に向けて2015

    • Author(s)
      落合雅子、松浦哲也、中釜 斉、筆宝義隆、今井俊夫
    • Organizer
      がん予防学術大会2015さいたま
    • Place of Presentation
      埼玉県さいたま市
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] マウス正常上皮細胞の3次元培養法を用いるin vitro発がんモデルの開発2015

    • Author(s)
      落合雅子、中釜 斉
    • Organizer
      日本環境変異原学会第44回大会
    • Place of Presentation
      福岡県福岡市
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] ウス正常腸管上皮の3次元培養法を用いる発がん再構成系に対するPhIPの修飾作用2015

    • Author(s)
      落合雅子、松浦哲也、中釜 斉、筆宝義隆、今井俊夫
    • Organizer
      第30回発がん病理研究会
    • Place of Presentation
      小豆島
    • Year and Date
      2015-08-26
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] 正常上皮細胞の3次元培養によるin vitro発がんモデルの開発-化学発がん・予防研究への応用に向けて2015

    • Author(s)
      落合雅子、松浦哲也、中釜 斉、筆宝義隆、今井俊夫
    • Organizer
      第22回日本がん予防学会
    • Place of Presentation
      さいたま
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス正常腸管上皮細胞の3次元培養系を用いる発がん再構成系に対するPhIPの修飾作用2015

    • Author(s)
      落合雅子、松浦哲也、中釜 斉、今井俊夫、筆宝義隆
    • Organizer
      第74回日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] 大腸異常腺窩似置けるムチンの性状変化は大腸発がんの初期変化である2007

    • Author(s)
      落合 雅子, 他
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-18590710
  • [Presentation] マウス肝臓初代培養細胞を用いた新規肝内胆管がんモデルの確立

    • Author(s)
      落合雅子,折橋 郁,松浦哲也,今井俊夫,中釜 斉,筆宝義隆
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] In vitro reconstitution of Kras-dependent tumorigenesis in the intestine and the stomach

    • Author(s)
      Kaoru Orihashi, Tetsuya Matsuura, Masako Ochiai, Toshio Imai, Hitoshi Nakagama, Yoshitaka Hippo
    • Organizer
      第73回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス肝臓初代培養細胞を用いた新規肝内胆管がんモデルの確立

    • Author(s)
      落合雅子,折橋 郁,松浦哲也,今井俊夫,中釜 斉,筆宝義隆
    • Organizer
      第29回発癌病理研究会
    • Place of Presentation
      福島県いわき市
    • Year and Date
      2014-09-01 – 2014-09-03
    • Data Source
      KAKENHI-PROJECT-26430134
  • 1.  NAKAGAMA Hitoshi (30198030)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  Hippo Yoshitaka (30359632)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 3.  UBAGAI Tsuneyuki (10311416)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  若林 敬二 (60158582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  田平 知子 (50155230)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  長尾 美奈子 (40100151)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  丸 喜明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi