KAKEI Masafumi 加計正文

… Alternative Names

加計正文カケイマサフミ

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Researcher Number	90214270
Other IDs
External Links
Affiliation (Current)	2025: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2016 – 2018: 自治医科大学, 医学部, 客員教授 2017: 自治医科大学, 医学部, 研究員 2012 – 2015: 自治医科大学, 医学部, 教授 2008 – 2010: Jichi Medical University, 医学部, 教授 2009: 医学部, 教授 … More 2000 – 2005: 秋田大学, 医学部, 助教授 2002: 秋田大学, 医学部付属病院, 助教授 2002: Akita University, School of medicine Hospital, Internal Medicine, Associate Professor, 医学部附属病院, 助教授 2001: 秋田大学, 医学部・附属病院, 助教授 1997 – 2000: 鹿児島大学, 医学部・附属病院, 講師 1998: 鹿児島大学, 医学部附属病院, 講師 1996: 鹿児島大学, 医学部附属病院, 講師 1995: 鹿児島大学, 医学部・附属病院, 講師 1994 – 1995: 鹿児島大学, 医学部, 講師 1993: 鹿児島大学, 医学部, 助手 1989 – 1991: 鹿児島大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Metabolomics / Metabolomics / 内分泌・代謝学 Except Principal Investigator General physiology / Metabolomics / Life / Health / Medical informatics / Applied pharmacology / Circulatory organs internal medicine / Metabolomics / Biological Sciences / General physiology / 医学一般
Keywords	Principal Investigator インスリン分泌 / 膵β細胞 / ATP / 糖尿病 / イオンチャネル / β細胞 / スルフォニル尿素薬 / PIP2 / K-ATPチャネル / insulin secretion … More / diabetes mellitus / β-cells / membrane phospholipid / sulfonylureas / K-ATP channels / 膜リン脂質 / SUR / グレリン / ＴＲＰＭ２ / 膵ラ氏島 / TRPM2 / 背景電流 / KATPチャネル / TRPM2チャネル / receptor operation / 受容体作動性調節 / actin / 細胞骨格 / ATP感受性K^+チャネル / アクチン / KIR / PANCREATIC B-CELLS / INSULIN SECRETION / SULFONYLUREA / K-ATP CHANNEL / Kir / PZP2 / スルフォニル尿素 / Pathch clamp / Ion channel / Insulin secretion / Ca channels / Pancreatic B-cells / バッケクランプ / パッチクランプ / イオンチャンネル / Caチャンネル / インクレチン / グルコース刺激インスリン分泌 / TRPチャネル / 膜電位機構 / membrane potential / diabetes / incretin / 膜電位固定 / カルシニューリン / 脱リン酸化 / 膜電位 / Kvチャネル / 糖質代謝異常 / エネルギー / K^+チャネル / 活性酸素 / ATP感受性Kチャネル … More Except Principal Investigator グルコース / インスリン分泌 / 膵β細胞 / PACAP / Ca^<2+> / NPY / インスリン / PACAP receptor / autocrine / islet / insulin secretion / サイクリックAMP / PACAP受容体 / オートクリン / ランゲルハンス島 / カルシウム / GKラット / グレリン / オレキシン / レプチン / 摂食中枢 / cAMP / Ca^<2+>ポンプ / 小胞体 / 膵島 / グルコ-ス / 細胞内カルシウム / イオンチャンネル / 発火パターン / 力学系理論 / QT延長 / 薬物有害反応 / 循環器 / 臨床薬理学 / rat / conduction system / Atrial natriuretic peptide / NeuropeptideY / Angiotensin II / ニューロペプタイド / アンキオテンシンII / オートレジオグラフィー / ラット / 刺激伝導系 / 心房利尿ホルモン / ニュ-ロペプタイドY / アンギオテンシンII / Cyclic AMP / Insulin secretion / Sulfonylurea receptor / スルホニルウレア受容体 / ghrelin / leptin / orexin / insulin / glucose / arcuate nucleus / feeding-regulatory centers / 腹内側核 / ニューロペプチドY / 外側視床下部 / 視床下部 / 細胞内Ca^<2+> / Protein KInase A / N型Ca^<2+>チャン / Neuropeptide Y / 弓状核 / glucose uptake / insulin action / adipocyte / ベータ細胞 / 膵 / グルコース取り込み / 脂肪細胞分化 / 3T3-L1 / 脂肪組織 / グルコース輸送 / 分化 / 脂肪細胞 / インスリン作用 / beta-cells / 受容体 / シグナル伝達 / 糖尿病 / 生理学 / β細胞 / GHS-R / グレリン受容体 / Kチャネル / HS-R / 膵島G / 糖代謝 / Kvチャネル / ニューロン / POMC / CAMP / アセチルコリン / Ca^<2+>放出 / 免疫組織化学 / カルシウムチャネル / カルシウムイオン / 膵beta細胞 / 代謝 / 顕微測定 / 単一膵β細胞 / 経口糖尿病薬 / Kチャネル電流 / 顕微測光 / パッチクランプ / 同時測定装置 Less

Functional coupling between proteins related to a novel triggered pathway for insulin secretion via TRPM2 in pancreatic beta-cells.Principal Investigator
- Principal Investigator
  
  KAKEI Masafumi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Jichi Medical University
A mathematical study on artificial stimulation to pancreas in type 2 diabetes
- Principal Investigator
  
  ANDO Hiroyasu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  University of Tsukuba
Development of a method to attenuate the adverse effect of anti-arrhythmic bepridil
- Principal Investigator
  
  Fujimura Akio
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Jichi Medical University
A study of neuronal and hormonal mediations of insulin secretion by inretins.Principal Investigator
- Principal Investigator
  
  KAKEI Masafumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Jichi Medical University
グルコースとホルモン情報を統合する膵β細胞Kv・TRPチャネルのセンサー機構
- Principal Investigator
  
  出崎克也
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Jichi Medical University
Ghrelin : its status as a pancreatic hormone, mechanisms by which it regulates insulin release and glucose metabolism, and its application for treating diabetes.
- Principal Investigator
  
  YADA Toshihiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Jichi Medical University
IKdelay is related to a novel GLP-1 pathway that is KATP-independent insulin secretion.Principal Investigator
- Principal Investigator
  
  KAKEI Masafumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Jichi Medical University
Identification of the impaired sites of cAMP pathways in sulfonylurea receptor 1 knockout islets.
- Principal Investigator
  
  NAKAZAKI Mitsuhiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kagoshima University
Study on multimolecular modulations of ATP-sensitive K^+ channels in pancreatic β-cells and their disharmony in diabetes.Principal Investigator
- Principal Investigator
  
  KAKEI Masafumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Akita University
Regulation by glucose and insulin of the neurons in feeding-regulatory centers and its alteration in obesity and diabetes
- Principal Investigator
  
  YADA Toshihiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Jichi Medical School
Studies on multimolecular modulation of ATP-sensitive K^+ channels in pancreatic β-cellsPrincipal Investigator
- Principal Investigator
  
  KAKEI Masafumi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Akita University
  Kagoshima University
食欲・代謝中枢の単一ニューロン活動計測と調節因子同定・作用機構解析の実験法の確立
- Principal Investigator
  
  矢田俊彦
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Kagoshima University
FACTORS OF STRUCTURE AND FUNCTION COUPLING BETWEEN SUR/KIR6.2IN PANCREATIC B-CEELSPrincipal Investigator
- Principal Investigator
  
  KAKEI Masafumi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  KAGOSHIMA UNIVERSITY
ATP-活性化K^+チャネルを介した新規インスリン分泌制御機構についての研究Principal Investigator
- Principal Investigator
  
  加計正文
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  内分泌・代謝学
- Research Institution
  Kagoshima University
Control of glucose metabolism by PACAP : stimulation of insulin secretion and potentiation of insulin action
- Principal Investigator
  
  YADA Toshihiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
膵β細胞小胞体Ca^<2+>ポンプとCa^<2+>放出チャネルの機能協関とインスリン分泌制御
- Principal Investigator
  
  矢田俊彦
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kagoshima University
膵β細胞小胞体Ca^<2+>ポンプとCa^<2+>放出チャネルの機能協関とインスリン分泌制御
- Principal Investigator
  
  矢田俊彦
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kagoshima University
活性酸素による膵β細胞インスリン分泌障害のイオンチャネルメカニズムPrincipal Investigator
- Principal Investigator
  
  加計正文
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Kagoshima University
Extraordinarily Potent Insulinotropin PACAP : Its Characterization as a Pancreatic Peptide and Action Mechanisms in Islet beta-Cells
- Principal Investigator
  
  YADA Toshihiko
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
新しいインスリン分泌調節ペプチドとしてのPACAPの役割と膵beta細胞作用機構
- Principal Investigator
  
  矢田俊彦
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
膵β細胞におけるグルコ-ス刺激に対する細胞内Ca応答の解析
- Principal Investigator
  
  矢田俊彦
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Characteristics of the Ca channel from pancreatic B-cells and its modulation by glucosePrincipal Investigator
- Principal Investigator
  
  KAKEI Masafumi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Kagoshima University
単一細胞の分泌・収縮と細胞内機能制御因子群の電気的光学的同時測定装置の試作
- Principal Investigator
  
  YADA Toshihiko
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  医学一般
- Research Institution
  Kagoshima University
Presence and physiological function of some endogeneous peptides in the conduction system of rat hearts.
- Principal Investigator
  
  SAITOU Kazuto
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Institute of Fitness and Sports in Kanoya
  Kagoshima University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2004 Other

All Journal Article Presentation

[Journal Article] ELKS/Voltage-dependent Ca2+ channel-β Subunit Module Regulates Polarized Ca2+ Influx in Pancreatic β-Cells.2019
- Author(s)
  Ohara-Imaizumi, M., Aoyagi, K., Yamauchi, H., Yoshida, M., Mori, M.X., Hida, Y., Tran, H.N., Ohkura, M., Abe, M., Akimoto, Y., Nakamichi, Y., Nishiwaki, C., Kawakami, H., Hara, K., Sakimura, K., Nagamatsu, S., Mori, Y., Nakai, J., Kakei, M., and Ohtsuka, T.
- Journal Title
  
  Cell Reports
  
  Volume: 26 Issue: 5 Pages: 1213-1226
- DOI
  10.1016/j.celrep.2018.12.106
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08547, KAKENHI-PROJECT-17K09845, KAKENHI-PROJECT-18K08525, KAKENHI-PLANNED-16H06536, KAKENHI-PUBLICLY-17H05560, KAKENHI-PUBLICLY-17H05741, KAKENHI-PROJECT-16H05140, KAKENHI-PROJECT-15K09396, KAKENHI-PROJECT-16K19545, KAKENHI-PROJECT-17K01972, KAKENHI-PUBLICLY-19H05014, KAKENHI-PROJECT-19H03324
[Journal Article] KATP/TRPチャネルの協調的インスリン分泌調節、破綻と病態2018
- Author(s)
  加計正文
- Journal Title
  
  心電図
  
  Volume: 38 Pages: 142-147
- NAID
  130007553671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09396
[Journal Article] Endogenous α2A-adrenoceptor-operated sympathoadrenergic tones attenuate insulin secretion via cAMP/TRPM2 signaling.2017
- Author(s)
  Ito K, Dezaki K, Yoshida M, Yamada H, Miura R, Rita RS, Ookawara S, Tabei K, Kawakami M, Hara K, Morishita Y, Yada T, Kakei M
- Journal Title
  
  Diabetes
  
  Volume: 66(3) Issue: 3 Pages: 699-709
- DOI
  10.2337/db16-1166
- NAID
  40021363366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670453, KAKENHI-PROJECT-15K09396, KAKENHI-PROJECT-15K09397, KAKENHI-PROJECT-16K15182, KAKENHI-PROJECT-16K19545
[Journal Article] Glucose and GTP-binding protein-coupled receptor cooperatively regulate transient receptor potential-channels to stimulate insulin secretion [Review]2016
- Author(s)
  Kakei M, Yoshida M, Dezaki K, Ito K, Yamada H, Funazaki S, Kawakami M, Sugawara H, and Yada T
- Journal Title
  
  Endocr J
  
  Volume: 63 Issue: 10 Pages: 867-876
- DOI
  10.1507/endocrj.EJ16-0262
- NAID
  130005267891
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09396, KAKENHI-PROJECT-26460916
[Journal Article] The beta-cell GHSR and downstream cAMP/TRPM2 signaling account for insulinostatic and glycemic effects of ghrelin.2015
- Author(s)
  Kurashina T, Dezaki K, Yoshida M, Sukma Rita R, Ito K, Taguchi M, Miura R, Tominaga M, Ishibashi S, Kakei M, Yada T
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 1-13
- DOI
  10.1038/srep14041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09396, KAKENHI-PROJECT-15K09397, KAKENHI-PROJECT-26870532
[Journal Article] Peripheral oxytocin activates vagal afferent neurons to suppress feeding in normal and leptin-resistant mice: a route for ameliorating hyperphagia and obesity.2015
- Author(s)
  Iwasaki, Y., Y. Maejima, S. Suyama, M. Yoshida, T. Arai, K. Katsurada, P. Kumari, H. Nakabayashi, M. Kakei, and T. Yada,
- Journal Title
  
  Am J Physiol Regul Integr Comp Physiol.
  
  Volume: 308 Issue: 5 Pages: R360-R369
- DOI
  10.1152/ajpregu.00344.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591340, KAKENHI-PROJECT-26460302, KAKENHI-PROJECT-26670453, KAKENHI-PROJECT-15K09396
[Journal Article] Partial Blockade of Kv2.1 Channel Potentiates GLP-1's Insulinotropic Effects in Islets and Reduces Its Dose Required for Improving Glucose Tolerance in Type 2 Diabetic Male Mice.2015
- Author(s)
  Sukma Rita, R., K. Dezaki, T. Kurashina, M. Kakei, and T. Yada,
- Journal Title
  
  Endocrinology.
  
  Volume: Endocrinology. 1(1): Issue: 1 Pages: 114-123
- DOI
  10.1210/en.2014-1728
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591340, KAKENHI-PROJECT-26670453, KAKENHI-PROJECT-15K09396
[Journal Article] Arcuate Na+,K+-ATPase senses systemic energy states and regulates feeding behavior through glucose-inhibited neurons.2015
- Author(s)
  Kurita H, Xu KY, Maejima Y, Nakata M, Dezaki K, Santoso P, Yang Y, Arai T, Gantulga D, Muroya S, Lefor AK, Kakei M, Watanabe E, Yada T.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 309 Issue: 4 Pages: 320-333
- DOI
  10.1152/ajpendo.00446.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09395, KAKENHI-PROJECT-15K09396, KAKENHI-PROJECT-24592277
[Journal Article] Circulating betatrophin is elevated in patients with type 1 and type 2 diabetes2015
- Author(s)
  Yamada H, Saito T, Aoki A, Asano T, Yoshida M, Ikoma A, Kusaka I, Toyoshima H, Kakei M, Ishikawa S E
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 5 Pages: 417-421
- DOI
  10.1507/endocrj.EJ14-0525
- NAID
  130005071800
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09396
[Journal Article] Prediction of 90-day mortality in patients without diabetes by severe hypoglycemia: blood glucose level as a novel marker of severity of underlying disease.2015
- Author(s)
  Tsujimoto, T., R. Yamamoto-Honda, H. Kajio, M. Kishimoto, H. Noto, R. Hachiya, A. Kimura, M. Kakei, and M. Noda,
- Journal Title
  
  Acta Diabetol.
  
  Volume: 52 Issue: 2 Pages: 307-314
- DOI
  10.1007/s00592-014-0640-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591340
[Journal Article] Vital signs, QT prolongation, and newly diagnosed cardiovascular disease during severe hypoglycemia in type 1 and type 2 diabetic patients.2014
- Author(s)
  Tsujimoto T, Yamamoto-Honda R, Kajio H, Kishimoto M, Noto H, Hachiya R, Kimura A, Kakei M, Noda M:
- Journal Title
  
  Diabetes Care
  
  Volume: 37 Pages: 217-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591340
[Journal Article] Involvement of cAMP-EPAC-TRPM2 activation in glucose- and incretin-induced insulin secretion2014
- Author(s)
  Yoshida M, Dezaki K, Uchida K, Kodera S, Lam NV, Ito K, Rita RS, Yamada H, Shimomura K, Ishikawa SE, Sugawara H, Kawakami M, Tominaga M, Yada T, Kakei M
- Journal Title
  
  Diabetes
  
  Volume: (Epub ahead of print) Issue: 10 Pages: 3394-3403
- DOI
  10.2337/db13-1868
- NAID
  40020531124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591320, KAKENHI-PROJECT-24591340, KAKENHI-PROJECT-24890219, KAKENHI-PROJECT-26460916, KAKENHI-PROJECT-26870532
[Journal Article] Involvement of cAMP-EPAC-TRPM2 activation in glucose- and incretin-induced insulin secretion.2014
- Author(s)
  Masashi Yoshida, Katsuya Dezaki, Kunitoshi Uchida, Shiho Kodera, Nien V. Lam, Kiyonori Ito, Rauza S. Rita, Hodaka Yamada, Kenju Shimomura, San-e Ishikawa, Hitoshi Sugawara, Masanobu Kawakami, Makoto Tominaga, Toshihiko Yada Masafumi Kakei1
- Journal Title
  
  Diabetes
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591340
[Journal Article] Serotonin regulates glucose-stimulated insulin secretion from pancreatic beta cells during pregnancy2013
- Author(s)
  Ohara-Imaizumi M, Kim H, Yoshida M, Fujiwara T, Aoyagi K, Toyofuku Y, Nakamichi Y, Nishiwaki C, Okamura T, Uchida T, Fujitani Y, Akagawa K, Kakei M, Watada H, German MS, Nagamatsu S:
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 110 Pages: 19420-19425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591340
[Journal Article] alpha-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs2013
- Author(s)
  Kumazaki, M., Ando, H., Kakei, M., Ushijima, K., Taniguchi, Y., Yoshida, M., Yamato, S., Washino, S., Koshimizu, T.A., and Fujimura, A
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 705 Pages: 1-10
- Data Source
  KAKENHI-PROJECT-24591340
[Journal Article] Insulin Activates Vagal Afferent Neurons Including those Innervating Pancreas via Insulin Cascade and Ca2+ Influx: Its Dysfunction in IRS2-KO Mice with Hyperphagic Obesity.2013
- Author(s)
  Iwasaki Y1, Shimomura K, Kohno D, Dezaki K, Ayush EA, Nakabayashi H, Kubota N, Kadowaki T, Kakei M, Nakata M, Yada T.
- Journal Title
  
  PLoS One.
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591340
[Journal Article] Inhibition of insulin secretion from rat pancreatic islets by dexmedetomidine and medetomidine, two sedatives frequently used in clinical settings2013
- Author(s)
  Yamato Kodera, S., Yoshida, M., Dezaki, K., Yada, T., Murayama, T., Kawakami, M., and Kakei, M.
- Journal Title
  
  Endocr J
  
  Volume: 60 Pages: 337-346
- NAID
  10031170619
- Data Source
  KAKENHI-PROJECT-24591340
[Journal Article] Pancreatic polypeptide and peptide YY3-36 induce Ca2+ signaling in nodose ganglion neurons2013
- Author(s)
  Iwasaki, Y., Kakei, M., Nakabayashi, H., Ayush, E.A., Hirano-Kodaira, M., Maejima, Y., and Yada, T.
- Journal Title
  
  Neuropeptides
  
  Volume: 47 Pages: 19-23
- Data Source
  KAKENHI-PROJECT-24591340
[Journal Article] Exogenous and endogenous ghrelin counteracts GLP-1 action to stimulate cAMP signaling and insulin secretion in islet beta-cells2012
- Author(s)
  Damdindorj, B., Dezaki, K., Kurashina, T., Sone, H., Rita, R., Kakei, M., and Yada, T.
- Journal Title
  
  FEBS Lett
  
  Volume: 586 Pages: 2555-2562
- Data Source
  KAKENHI-PROJECT-24591340
[Journal Article] Circulating osteocalcin is increased in early-stage diabetes.2011
- Author(s)
  Aoki, A., Muneyuki, T., Yoshida, M., Munakata, H., Ishikawa, S. E., Sugawara, H., Kawakami, M., Kakei, M.
- Journal Title
  
  Journal
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Low serum amylase in association with metabolic syndrome and diabetes : A community-based study.2011
- Author(s)
  Nakajima, K., Nemoto, T., Muneyuki, T., Kakei, M., Fuchigami, H., Munakata, H.
- Journal Title
  
  Journal 10
  
  Pages: 34-34
- NAID
  120005518443
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis.2010
- Author(s)
  Ohara-Imaizumi M, Yoshida M, Aoyagi K, Saito T, Okamura T, Takenaka H, Akimoto Y, Nakamichi Y, Takanashi-Yanobu R, Nishiwaki C, Kawakami H, Kato N, Hisanaga S, Kakei M, Nagamatsu S.
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Voltage-dependent metabolic regulation of Kv2.1 channels in pancreatic beta-cells.2010
- Author(s)
  Yoshida M, Nakata M, Yamato S, Dezaki K, Sugawara H, Ishikawa SE, Kawakami M, Yada T, Kakei M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 396 Pages: 304-309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Voltage-dependent metabolic regulation of Kv2.1 channels in pancreatic beta-cells.2010
- Author(s)
  Yoshida, M., Nakata, M., Yamato, S., Dezaki, K., Sugawara, H., Ishikawa, S. E., Kawakami, M., Yada, T., Kakei, M.
- Journal Title
  
  Journal 396
  
  Pages: 304-309
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Voltage-dependent metabolic regulation of Kv2.1 channels in pancreatic β-cells2010
- Author(s)
  Yoshida M., Nakata M., Yamato S., Dezaki K., Sugawara H., Ishikawa S., Kawakami M., Yada T., Kakei M.
- Journal Title
  
  Biochem.Biophys.Res.Commun 396
  
  Pages: 304-309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390061
[Journal Article] Class IA phosphatidylinositol 3-kinase inpancreatic β cells controls insulin secretion by multiple mechanisms.2010
- Author(s)
  Kaneko K, Ueki K, Takahashi N, Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T, Yo shida M, Kakei M, Kitamura T, Luo J, Kulkarni RN, Kahn CR, Kasai H, Cantley LC, Kadowaki T
- Journal Title
  
  Cell Metab.
  
  Volume: 12 Pages: 619-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Class IA phosphatidylinositol 3-kinase in pancreatic beta cells controls insulin secretion by multiple mechanisms.2010
- Author(s)
  Kaneko, K., Ueki, K., Takahashi, N., Hashimoto, S., Okamoto, M., Awazawa, M., Okazaki, Y., Ohsugi, M., Inabe, K., Umehara, T., Yoshida, M., Kakei, M., Kitamura, T., Luo, J., Kulkarni, R. N., Kahn, C. R., Kasai, H., Cantley, L. C., Kadowaki, T.
- Journal Title
  
  Journal 12
  
  Pages: 619-632
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis.2010
- Author(s)
  Ohara-Imaizumi, M., Yoshida, M., Aoyagi, K., Saito, T., Okamura, T., Takenaka, H., Akimoto, Y., Nakamichi, Y., Takanashi-Yanobu, R., Nishiwaki, C., Kawakami, H., Kato, N., Hisanaga, S., Kakei, M., Nagamatsu, S.
- Journal Title
  
  Journal 5
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Regulation of voltage-gated K+ channels by glucose metabolism in pancreatic beta-cells.2009
- Author(s)
  Yoshida, M., Dezaki, K., Yamato, S., Aoki, A., Sugawara, H., Toyoshima, H., Ishikawa, S. E., Kawakami, M., Nakata, M., Yada, T., Kakei, M.
- Journal Title
  
  Journal 583
  
  Pages: 2225-2230
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Nesfatin-1 evokes Ca^<2+> signaling in isolated vagal afferent neurons via Ca^<2+> influx through N-type channels2009
- Author(s)
  Y.Iwasaki, H.Nakabayashi, M.Kakei, H.Shimizu, M.Mori, T.Yada
- Journal Title
  
  Biochem Biophys Res Commun 390
  
  Pages: 958-962
- NAID
  120001871396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Regulation of voltage-gated K^+ channels by glucose metabolism in pancreatic β-cells2009
- Author(s)
  Yoshida M., Dezaki K., Yamato S., Aoki A., Sugawara H., Toyoshima H., Ishikawa S., Kawakami M., Nakata M., Yada T., Kakei M.
- Journal Title
  
  FEBS Lett 583
  
  Pages: 2225-2230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390061
[Journal Article] Regulation of voltage-gated K^+ channels by glucose metabolism in pancreatic beta-cells2009
- Author(s)
  M.Yoshida, K.Dezaki, S.Yamato, A.Aoki, H.Sugawara, H.Toyoshima, S.E.Ishikawa, M.Kawakami, M.Nakata, T.Yada, M.Kakei
- Journal Title
  
  FEBS Lett 583
  
  Pages: 2225-2230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] Ghrelin regulates insulin release and glycemia : physiological role and therapeutic potential.2008
- Author(s)
  Yada T, Dezaki K, Sone H, Koizumi M, Damdindorj B, Nakata M, Kakei M
- Journal Title
  
  Curr Diabetes Rev. 4(1)
  
  Pages: 18-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591071
[Journal Article] ブドウ糖によるインスリン分泌機構-特にKATPチャネルについて-2004
- Author(s)
  中崎満浩, 加計正文
- Journal Title
  
  糖尿病カレントライブラリー(2)
  
  Pages: 13-18
- Data Source
  KAKENHI-PROJECT-16590891
[Journal Article] Nesfatin-1 evokes Ca(2+) signaling in isolated vagal afferent neurons via Ca(2+) influx through N-type channels.
- Author(s)
  Iwasaki, Y., Nakabayashi, H., Kakei, M., Shimizu, H., Mori, M., Yada, T.
- Journal Title
  
  Journal 2009
- NAID
  120001871396
- Data Source
  KAKENHI-PROJECT-20591071
[Presentation] アクティブゾーンタンパク質ELKSのインスリン分泌における役割2018
- Author(s)
  今泉美佳1, 青柳共太1, 吉田昌史2, 飛田耶馬人3, 大倉正道4,5, 山内肇3, 﨑村建司6, 中井淳一4,5, 加計正文2, 永松信哉1, 大塚稔久3
- Organizer
  第61回日本糖尿病学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09396
[Presentation] 膵β細胞GPR40シグナルはPLC-PKC-TrpC経路を介してインスリン分泌を増強する2018
- Author(s)
  山田穂高1, 船崎俊介1, 吉田昌史1, 伊藤聖学2, 出崎克也3, 川上正舒4, 矢田俊彦3, 石川三衛5, 加計正文1, 原一雄1
- Organizer
  第61回日本糖尿病学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09396
[Presentation] TRPM2チャネルの膜電位特性の数理モデル解析2017
- Author(s)
  藤原寛太郎，安東弘泰，池口徹，吉田昌史，加計正文
- Organizer
  日本糖尿病学会年次学術集会論文集
- Data Source
  KAKENHI-PROJECT-15K12137
[Presentation] TRPM2チャネルの膜電位特性の数理モデル解析2017
- Author(s)
  藤原寛太郎, 安東弘泰, 池口徹, 吉田昌史, 加計正文
- Organizer
  第６0回日本糖尿病学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09396
[Presentation] 膵β細胞の数理モデルにおけるノイズの影響について2017
- Author(s)
  古城知祥・安東弘泰・藤原寛太郎・吉田昌史・加計正文
- Organizer
  電子情報通信学会技術研究報告
- Data Source
  KAKENHI-PROJECT-15K12137
[Presentation] Mathematical Model of TRPM2 Activation in Pancreatic β-cells2017
- Author(s)
  Kantaro Fujiwara, Hiroyasu Ando, Tohru Ikeguchi, Masashi Yoshida and Masafumi Kakei
- Organizer
  Proceedings of the 2017 International Symposium on Nonlinear Theory and its Applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12137
[Presentation] 生理学的低濃度のアドレナリンはcAMP/TRPM経路を介してインスリン分泌を抑制する2017
- Author(s)
  伊藤聖学, 出崎克也, 吉田昌史, 山田穂高, 三浦李菜, 大河原晋, 田部井薫, 川上正舒, 原一雄, 森下義幸, 矢田俊彦, 加計正文
- Organizer
  第６0回日本糖尿病学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09396
[Presentation] 新規ブドウ糖刺激インスリン分泌惹起経路としてのTrpm22015
- Author(s)
  吉田昌史，出崎克也，中田正範，内田邦敏，伊藤聖学，山田穂高，富永真琴，川上正舒，矢田俊彦，加計正文
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K09396
[Presentation] Activation of Trpm2 Channel by Glucose Metabolism and GLP-1 in Pancreatic Beta-Cell2013
- Author(s)
  MASASHI YOSHIDA, SHIHO YAMATO, KATSUYA DEZAKI, MASANOBU KAWAKAMI, TOSHIHIKO YADA, MASAFUMI KAKEI
- Organizer
  73rd Scientific Session of American Diabetes Association
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-24591340
[Presentation] Serotonin Regulates Glucose Stimulated Insulin Secretion from Pancreatic β-Cells during Pregnancy2013
- Author(s)
  MICA OHARA-IMAIZUMI, HAIL KIM, MASASHI YOSHIDA, YUKIKO TOYOFUKU, TADASHI OKAMURA, TOYOYOSHI UCHIDA, YOSHIO FUJITANI, MASAFUMI KAKEI, HIROTAKA WATADA, MICHAEL S. GERMAN, SHINYA NAGAMATSU,
- Organizer
  73rd Scientific Session of American Diabetes Association
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-24591340
[Presentation] 妊娠期膵β細胞でのセロトニンによるインスリン分泌亢進機構2012
- Author(s)
  今泉美佳、吉田昌史、豊福優希子、青柳共太、中道洋子、西脇知世乃、加計正文、綿田裕孝、永松信哉
- Organizer
  第55回日本糖尿病学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591340
[Presentation] 膵β細胞グルコース刺激活動電位形成持のCa2+依存性Kv2.1チャネルの役割2012
- Author(s)
  吉田昌史、中田正範、大和志保、出崎克也、石川三衛、川上正舒、矢田俊彦、加計正文
- Organizer
  第55回日本糖尿病学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591340
[Presentation] Voltage-gated Potassium Channels in Pancreatic β-cells are Regulated via Phosphorylation/dephosphorylatio and Divalent Cations.2011
- Author(s)
  Yoshida M, Yamato S, Nakata M, Ishikawa S, Kawakami M, Yada, T, Kakei M
- Organizer
  71^<st> The Meeting of Amereican Diabetes Association
- Place of Presentation
  San-Diaego
- Data Source
  KAKENHI-PROJECT-20591071
[Presentation] グレリンによるインスリン分泌制2010
- Author(s)
  出崎克也, Damdindorj Boldbaatar, 加計正文, 矢田俊彦
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] 膵β細胞Kv2.1チャネルの代謝依存性調節機構2010
- Author(s)
  加計正文, 吉田昌史, 出崎克也, 青木厚, 菅原斉, 豊島秀男, 石川三衛, 川上正舒, 中田正範, 矢田俊彦
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] Kv2.1-channel currents are mediated by phosphorylation of the channels during glucose stimulation2010
- Author(s)
  Yoshida M, Kakei M, et al.
- Organizer
  70^<th> Scientific Sessions for American Diabetes Association.
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-20591071
[Presentation] Kv2.1-channel currents are mediated by phosphorylation of the channels during glucose stimulation2010
- Author(s)
  吉田昌史, 出崎克也, 青木厚, 豊島秀男, 石川三衛, 川上正舒, 中田正範, 矢田俊彦., 加計正文
- Organizer
  The American Diabetes Association 70th scientific sessions Abstracts: Diabetes:59(suppl. 1)A454, 2010
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] シンポジウム9:膵β細胞研究の最前線(1)「インスリン分泌」Cell metabolism-dependent regulation of Kv channels in pancreatic β-cells.2010
- Author(s)
  加計正文、吉田昌史、大和志保、石川三衛、川上正舒
- Organizer
  第53回日本糖尿病学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20591071
[Presentation] グレリンによるβ細胞Kv2.1チャネル活性化を介したグルコース誘発インスリン分泌抑制2010
- Author(s)
  出崎克也, Damdindorj Boldbaatar, 加計正文, 矢田俊彦
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] Ghrelin receptor antagonist improves glucose intolerance in type 2 diabetic GK rats.2010
- Author(s)
  Damdindorj B., Dezaki K., Sone H., Yaguchi T., Kakei M., Yada T.
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] 膵β細胞Kv2.1チャネルの代謝依存性調節機構2010
- Author(s)
  加計正文、吉田昌史、出崎克也、青木厚、菅原斉、豊島秀雄、石川三衛、川上正舒、中田正範、矢田俊彦
- Organizer
  第53回日本糖尿病学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20591071
[Presentation] 膵β細胞Kv2.1チャネルのブドウ糖代謝による新規調節機構2009
- Author(s)
  吉田昌史、出崎克也、青木厚、菅原斉、豊島秀男、石川三衛、川上正舒、中田正範、矢田俊彦、加計正文
- Organizer
  第52回日本糖尿病学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591071
[Presentation] Ghrelin receptor antagonist potentiates glucose-induced insulin release in diabetic GK rats2009
- Author(s)
  Damdindorj B., Dezaki K., Sone H., Kakei M., Yada T.
- Organizer
  The 36th International Congress of Physiological Sciences (IUPS)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] Excessive expression and activity of Kv2.1 channels in islet β-cells of type 2 diabetic GK rats2009
- Author(s)
  Dezaki K., Damdindorj B., Ando A., Yoshida M., Kakei M., Yada T.
- Organizer
  45^<th> EASD Annual Meeting
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] Kv2.1 channel blockers enhance glucose-induced cytosolic Ca^<2+> increases and insulin release in islet β-cells of type 2 diabetic rats2009
- Author(s)
  Dezaki K., Damdindorj B., Kakei M., Yada T.
- Organizer
  The 36th International Congress of Physiological Sciences (IUPS)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] Ghrelin activates voltage-dependent K^+ channels by modulation of cAMP/PKA signaling in islet β-cells2009
- Author(s)
  Dezaki K., Damdindorj B., Yoshida M., Kakei M., Yada T.
- Organizer
  The 2009 International Symposium on Ghrelin
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] Ghrelin receptor antagonist enhances glucose-induced insulin release in type 2 diabetic GK rats2009
- Author(s)
  Damdindorj B., Dezaki K.,Sone H., Yaguchi T., Kakei M., Yada T.
- Organizer
  The 2009 International Symposium on Ghrelin
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] ブドウ糖刺激インスリン分泌におけるKvチャネル活動の役割2008
- Author(s)
  加計正文
- Organizer
  第51回日本糖尿病学会学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20591071
[Presentation] グレリンによるβ細胞Kvチャネル活性化を介したグルコース誘発インスリン分泌抑制2008
- Author(s)
  出崎克也, Damdindorj Boldbaatar, 加計正文, 矢田俊彦
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390061
[Presentation] GRP40/FFR1を介する新規インスリン分泌メカニズム
- Author(s)
  山田穂高、吉田昌史、伊藤聖学、川上正舒、矢田俊彦、石川三衛、加計正文
- Organizer
  第57回日本糖尿病学会総会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591340
[Presentation] 膵β細胞Trpm2チャネルはインクレチンホルモン・グルコース代謝依存性に開港し、インスリン分泌を刺激する
- Author(s)
  吉田昌史、出崎克也、中田正範、山田穂高、石川三衛、矢田俊彦、川上正舒、加計正文
- Organizer
  第57回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591340

1. YADA Toshihiko (60166527)

# of Collaborated Projects: 18 results

# of Collaborated Products: 25 results
2. SHIODA Seiji (80102375)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. TANAKA Hiromitsu (80041292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. DEZAKI Katsuya (90337329)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. NAKATA Masanori (10305120)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. ITO Seiki (40126389)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MARUYAMA Ikuro (20082282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SAKURAI Takeshi (60251055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAGI Takeshi (10241241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAKAZAKI Mitsuhiro (40363626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. KORIYAMA Nobuyuki (50363643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAITOU Kazuto (50170494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Fujimura Akio (90156901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ANDO Hitoshi (50382875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KOSHIMIZU Takaaki (20392491)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SHIGA Tsuyoshi (00277211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ANDO Hiroyasu (20553770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. IKEGUCHI Tohru (30222863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 反町勝 (70036440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 井樋田香織 (60184793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 藤原寛太郎 (00557704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. TORII Kunio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MAEJIMA Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 今泉美佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAKEI Masafumi 加計 正文

加計 正文 カケイ マサフミ

Research Projects

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Functional coupling between proteins related to a novel triggered pathway for insulin secretion via TRPM2 in pancreatic beta-cells.Principal Investigator

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A study of neuronal and hormonal mediations of insulin secretion by inretins.Principal Investigator

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IKdelay is related to a novel GLP-1 pathway that is KATP-independent insulin secretion.Principal Investigator

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Study on multimolecular modulations of ATP-sensitive K^+ channels in pancreatic β-cells and their disharmony in diabetes.Principal Investigator

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Studies on multimolecular modulation of ATP-sensitive K^+ channels in pancreatic β-cellsPrincipal Investigator

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FACTORS OF STRUCTURE AND FUNCTION COUPLING BETWEEN SUR/KIR6.2IN PANCREATIC B-CEELSPrincipal Investigator

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ATP-活性化K^+チャネルを介した新規インスリン分泌制御機構についての研究Principal Investigator

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KAKEI Masafumi 加計正文

加計正文カケイマサフミ