TAKAHASHI Mami 高橋真美

… Alternative Names

高橋真美タカハシマミ

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Researcher Number	90214973
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 研究所, 研究員
Affiliation (based on the past Project Information) *help	2024: 国立研究開発法人国立がん研究センター, 研究所, ユニット長 2015 – 2022: 国立研究開発法人国立がん研究センター, 研究所, ユニット長 2010 – 2014: 独立行政法人国立がん研究センター, 研究所, ユニット長 2006 – 2007: 国立がんセンター(研究所及び東病院臨床開発センター), がん予防基礎研究プロジェクト, 室長 2004: Natl.Cancer Ctr.Res.Inst., Cancer Prev.Basic Res., Proj., がん予防基礎研究プロジェクト, 室長 … More 2003: 国立がんセンター, 研究所・がん予防基礎研究プロジェクト, 室長 2001: 国立がんセンター, 研究所・がん予防研究所, 研究員 2000 – 2001: 国立がんセンター, 研究所・がん予防研究部, 研究員 1996: 国立がんセンター研究所, 生化学部, 研究員 Less
Review Section/Research Field	Principal Investigator Experimental pathology / Tumor biology / Basic Section 49030:Experimental pathology-related / Experimental pathology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 38050:Food sciences-related
Keywords	Principal Investigator PPARγ / 膵臓がん / 大腸がん / BOP / Lipoprotein lipase / Hyperlipidemia / PPARα / 高脂血症 / K-ras / COX-2 … More / iNOS / メラノコルチン受容体 / マウスモデル / 細胞株 / SNPs / 一塩基多型 / 悪性化 / 宿主環境要因 / 動物モデル / Diabetes / OLETF rat / Hamster / Pancreatic cancer / 糖尿病 / OLETFラット / リポ蛋白リパーゼ / ハムスター / 膵がん / Pioglitazone / Triglyceride / Intestinalpolyp / Apc knockoutmouse / ベザフィブレート / ピオグリタゾン / トリグリセリド / リポプロテインリパーゼ / 腸ポリープ / Apcノックアウトマウス / Mouse / Rat / Beta-catenin / Colon cancer / INOS / マウス / ラット / β-カテニン / アグーチ / がん予防 / バイオマーカー / スプライスバリアント / オステオポンチン / 腫瘍 … More Except Principal Investigator PDX / オルガノイド / 希少がん / 膵腺房細胞がん / 膵臓癌 / がん予防 / 癌幹細胞 / 癌化学予防 / 膵癌 / フコキサンチノール / 膵臓がん / 腫瘍微小環境 / がん化学予防 / 海藻 / フコキサンチン / カロテノイド / ドコサヘキサエン酸 / 大腸癌 / 一酸化窒素 / プロスタグランジン / シクロオキシゲナーゼ Less

Establishment and analysis of human pancreatic acinar cell carcinoma cell lines to elucidate the pathogenesis of rare cancers and to explore new treatment methods.
- Principal Investigator
  
  泉谷昌志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
Elucidation of molecular network-regulating mechanisms on pancreatic tumor microenvironment suppression by fucoxanthin
- Principal Investigator
  
  TERASAKI Masaru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Health Sciences University of Hokkaido
Involvement of melanocortin type 1 receptor dysfunction in pancreatic carcinogenesisPrincipal Investigator
- Principal Investigator
  
  Takahashi Mami
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  National Cancer Center Japan
Analysis of the effects of the host environment factors on pancreatic cancer malignancy at whole body levelsPrincipal Investigator
- Principal Investigator
  
  Takahashi Mami
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  National Cancer Center Japan
Involvement of the melanocortin receptor pathway in pancreatic and colorectal carcinogenesis and its application to cancer preventionPrincipal Investigator
- Principal Investigator
  
  Takahashi Mami
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  National Cancer Center Japan
Analysis of physical roles of osteopontin and its cancer-specific molecules in colorectal and pancreatic carcinogenesisPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Mami
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center Japan
Promotive effects of hyperlipidemia on pancreatic ductal carcinogenesis and the mechanismsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Mami
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
Relationship between the mechanism for hyperlipidemia and intestinal polyp formation in Apc knockout micePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Mami
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center
Relationship between activation of beta-catenin pathway and expression of inflamatory enzymes in colon carcinogenesis in experimental animalsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Mami
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center
大腸発癌におけるシクロオキシゲナーゼの関与とそのメカニズムの研究
- Principal Investigator
  
  福田一典
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2022 2021 2020 2019 2018 2016 2014 2013 2012 2011 2010 2006 Other

All Journal Article Presentation Book

[Book] V―11. 国立がん研究センター国立がん研究センター研究所FIOCでの上皮性腫瘍PDXモデルの樹立例。「患者由来がんモデルを用いたがん研究実践ガイド」編集/佐々木博己。2019
- Author(s)
  高橋真美、今井俊夫。
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18K07081
[Journal Article] Characterization of the large‐scale Japanese patient‐derived xenograft (J‐PDX) library2021
- Author(s)
  Yagishita Shigehiro、Kato Ken、Takahashi Mami、Imai Toshio、Yatabe Yasushi、Kuwata Takeshi、Suzuki Mikiko、Ochiai Atsushi、Ohtsu Atsushi、Shimada Kazuaki、Nishida Toshirou、Hamada Akinobu、Mano Hiroyuki
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 6 Pages: 2454-2466
- DOI
  10.1111/cas.14899
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07007, KAKENHI-PROJECT-20K21639, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-18K07081, KAKENHI-PROJECT-21K06939
[Journal Article] Effect of fucoxanthinol on pancreatic ductal adenocarcinoma cells from an N-nitrosobis(2-oxopropyl)amine-initiated Syrian golden hamster pancreatic carcinogenesis model.2021
- Author(s)
  Terasaki, M., Nishizaka, Y., Murase, W., Kubota, A., Kojima, H., Kojoma M., Tanaka, T., Maeda, H., Miyashita, K., Mutoh, M., Takahashi, M.
- Journal Title
  
  Cancer Genomics Proteomics
  
  Volume: 18 Issue: 3 Suppl Pages: 407-423
- DOI
  10.21873/cgp.20268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07081
[Journal Article] Fucoxanthin Prevents Pancreatic Tumorigenesis in C57BL/6J Mice That Received Allogenic and Orthotopic Transplants of Cancer Cells2021
- Author(s)
  Murase Wataru、Kamakura Yukino、Kawakami Serina、Yasuda Ayaka、Wagatsuma Momoka、Kubota Atsuhito、Kojima Hiroyuki、Ohta Tohru、Takahashi Mami、Mutoh Michihiro、Tanaka Takuji、Maeda Hayato、Miyashita Kazuo、Terasaki Masaru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 24 Pages: 13620-13620
- DOI
  10.3390/ijms222413620
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843, KAKENHI-PROJECT-18K07081, KAKENHI-PROJECT-20K05879
[Journal Article] 抗炎症薬・抗糖尿病薬・抗脂質異常症薬による膵がん化学予防の可能性2021
- Author(s)
  高橋真美
- Journal Title
  
  癌と化学療法
  
  Volume: 48 Pages: 1429-1434
- Data Source
  KAKENHI-PROJECT-18K07081
[Journal Article] A Marine Carotenoid of Fucoxanthinol Accelerates the Growth of Human Pancreatic Cancer PANC-1 Cells2021
- Author(s)
  Terasaki M, Takahashi S, Nishimura R, Kubota A, Kojima H, Ohta T, Hamada J, Kuramitsu Y, Maeda H, Miyashita K, Takahashi M, Mutoh M
- Journal Title
  
  Nutrition and Cancer
  
  Volume: 16 Issue: 1 Pages: 1-16
- DOI
  10.1080/01635581.2020.1863994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05879
[Journal Article] A fucoxanthinol induces apoptosis in a pancreatic 　intraepithelial neoplasia cells.2021
- Author(s)
  Terasaki, M., Takuya Inoue, T., Murase, W., Atsuhito Kubota, A., Kojma, H., Kojoma, M., Ohta, T., Maeda, H., Miyashita, K., Mutoh, M., Takahashi, M.
- Journal Title
  
  Cancer Genomics Proteomics
  
  Volume: 18 Issue: 2 Pages: 133-146
- DOI
  10.21873/cgp.20248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07081, KAKENHI-PROJECT-20K05879
[Journal Article] Activated ductal proliferation induced by N-nitrosobis(2-oxopropyl)amine in fat-induced pancreas of KK-Ay mice.2018
- Author(s)
  Hori, M., Mutoh, M., Ishigamori, R., Imai, T., Takahashi, M.
- Journal Title
  
  In Vivo
  
  Volume: 32 Issue: 3 Pages: 499-505
- DOI
  10.21873/invivo.11267
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14393
[Journal Article] Fatty pancreas: A possible risk factor for pancreatic cancer in animals and humans2018
- Author(s)
  Takahashi Mami、Hori Mika、Ishigamori Rikako、Mutoh Michihiro、Imai Toshio、Nakagama Hitoshi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 10 Pages: 3013-3023
- DOI
  10.1111/cas.13766
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07081, KAKENHI-PROJECT-17K08681
[Journal Article] Possible involvement of pancreatic fatty infiltration in pancreatic carcinogenesis.2016
- Author(s)
  Hori, M., Mutoh, M., Imai, T., Nakagama, H., Takahashi, M.
- Journal Title
  
  Journal of the Pancreas
  
  Volume: 17 Pages: 166-175
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25290049
[Journal Article] Involvement of inflammatory factors in pancreatic carcinogenesis and preventive effects of anti-inflammatory agents.2013
- Author(s)
  Takahashi, M., Mutoh, M., Ishigamori, R., Fujii, G., Imai, T.
- Journal Title
  
  Semin in Immunopathol,
  
  Volume: 35 Issue: 2 Pages: 203-227
- DOI
  10.1007/s00281-012-0340-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590342, KAKENHI-PROJECT-22590371
[Journal Article] A^y allele promotes azoxymethane-induced colorectal carcinogenesis via macrophage migration in hyperlipidemic/diabetic KK mice.2013
- Author(s)
  Ito, K., Ishigamori, R., Mutoh, M., Ohta, T., Imai, T., Takahashi, M
- Journal Title
  
  Cancer Sci.
  
  Volume: (in press) Issue: 7 Pages: 835-843
- DOI
  10.1111/cas.12162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590371, KAKENHI-PROJECT-25290049
[Journal Article] Experimental animal models of pancreatic carcinogenesis for prevention studies and their relevance to human disease.2011
- Author(s)
  Takahashi, M., et al.
- Journal Title
  
  Cancers
  
  Volume: 3 Pages: 582-602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590371
[Journal Article] Experimental animal models of pancreatic carcinogenesis for prevention studies and their relevance to human disease.2011
- Author(s)
  Takahashi, M., Hori, M., Mutoh, M., Wakabayashi, K., Nakagama, H
- Journal Title
  
  Cancers
  
  Volume: vol.3 Issue: 1 Pages: 582-602
- DOI
  10.3390/cancers3010582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590371
[Presentation] 患者由来がん細胞株による転移モデルマウスの開発2022
- Author(s)
  千脇　史子、小松　将之、高橋　真美、平岡　伸介、佐々木　博己、竹下　文隆
- Organizer
  第81回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07081
[Presentation] Fucoxanthin suppresses development of pancreatic cancer in allogenic and orthotopic murine model2022
- Author(s)
  Wataru Murase, Takuji Tanaka, Mami Takahashi and Michihiro Mutoh, Masaru Terasaki
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] フコキサンチンは同種同所移植マウスモデルによる転移モデルにおける膵がん発生を抑制する2022
- Author(s)
  村瀬　渉、田中卓二、高橋真美、武藤倫弘、寺崎　将
- Organizer
  第81回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07081
[Presentation] 患者由来膵がん細胞株におけるメラノコルチン４型受容体遺伝子近傍SNPのLOH及びアレル特異的遺伝子発現に関する解析2022
- Author(s)
  高橋　真美、千脇　史子、小松　将之、松崎　圭祐、平岡　伸介、竹下　文隆、佐々木　博己、今井　俊夫
- Organizer
  第81回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07081
[Presentation] フコキサンチンによる膵がん予防に対する免疫関連分子制御の検討2022
- Author(s)
  村瀬渉、寺崎将、窪田篤人、安田彩夏、植原治、田中卓二、高橋真美、小島弘幸
- Organizer
  第29回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] 170人の患者の腹水からの239株の腹膜転移性癌細胞株の樹立とその特徴2021
- Author(s)
  千脇史子、小松将之、坂本裕美、高橋真美、小松崎理絵、松下弘道、朴成和、平岡伸介、竹下文隆、市川仁、吉田輝彦、松崎圭祐、佐々木博己
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07081
[Presentation] 膵がん患者由来培養細胞株移植マウスモデルの構築と組織型に関する検討2020
- Author(s)
  高橋真美、石ケ守里加子、千脇史子、平岡伸介、佐々木博己、今井俊夫
- Organizer
  患者由来がんモデル講演会
- Data Source
  KAKENHI-PROJECT-18K07081
[Presentation] Increase of pancreatic cancer development in pancreas-specific K-ras mutant mice by crossing with obesity Ay mice and involvement of the M-CSF.2016
- Author(s)
  Takahashi, M.,Ishigamori, R.,Mutoh, M., Fujii, G., Miyamoto, S., Imai, T.
- Organizer
  Tenth AACR-JCA Joint Conference
- Place of Presentation
  米国ハワイ州
- Year and Date
  2016-02-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290049
[Presentation] Increase of pancreatic cancer development in pancreas-specific K-ras mutant mice by crossing with obesity Ay mice and involvement of the M-CSF2016
- Author(s)
  高橋真美、石ヶ守里加子、武藤倫弘、藤井元、宮本真吾、田中卓二、今井俊夫
- Organizer
  第10回日米癌合同会議
- Place of Presentation
  米国（ハワイ）
- Year and Date
  2016-02-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14393
[Presentation] 肥満モデルAyマウスにおける膵臓の脂肪浸潤のがんの発生・増殖に対する影響2016
- Author(s)
  高橋真美、石ヶ守里加子、武藤倫弘、田中卓二、今井俊夫
- Organizer
  がん予防学術大会2016名古屋
- Place of Presentation
  名古屋大学基礎医学研究棟（愛知県・名古屋市）
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-15K14393
[Presentation] Analysis of cancer promotion mechanisms using allograft models of mouse pancreatic adenocarcinoma cell lines2016
- Author(s)
  高橋真美、石ヶ守里加子、武藤倫弘、今井俊夫
- Organizer
  第75回日本癌学会
- Place of Presentation
  パシィフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K14393
[Presentation] Agoutiによるマウス膵臓発がん促進メカニズム2014
- Author(s)
  高橋真美、石ヶ守里加子、藤井元、武藤倫弘、今井俊夫
- Organizer
  第73回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-25290049
[Presentation] マウス膵臓発がんモデルにおけるAyアレルによる発がん促進とそのメカニズム2014
- Author(s)
  高橋真美、石ヶ守里加子、藤井元、武藤倫弘、今井俊夫
- Organizer
  NCC-NCGM合同リトリート
- Place of Presentation
  常総
- Year and Date
  2014-08-28
- Data Source
  KAKENHI-PROJECT-25290049
[Presentation] 膵臓特異的K-ras 変異体発現マウスの膵臓発がんにおけるオステオポンチンの作用2012
- Author(s)
  高橋真美、石ヶ守里加子、中西るり、武藤倫弘、今井俊夫
- Organizer
  第19回日本がん予防学会
- Place of Presentation
  じゅうろくプラザ(岐阜)
- Year and Date
  2012-06-22
- Data Source
  KAKENHI-PROJECT-22590371
[Presentation] 膵臓特異的K-ras 変異体発現マウスと肥満モデルA^y マウスとの交配による膵臓発がん促進2012
- Author(s)
  高橋真美、石ヶ守里加子、小宮雅美、武藤倫弘、今井俊夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌市教育文化会館(札幌)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22590371
[Presentation] 膵臓特異的K-ras変異体発現マウスの膵臓発がんにおけるオステオポンチンの発現上昇2011
- Author(s)
  高橋真美
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22590371
[Presentation] 臓特異的K-ras 変異体発現マウスの膵臓発がんにおけるオステオポンチンの発現上昇2011
- Author(s)
  高橋真美、石ヶ守里加子、堀美香、高須伸二、今井俊夫、武藤倫弘、若林敬二
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22590371
[Presentation] ハムスター膵管発がんにおけるオステオポンチンとそのスプライシングバリアントの発現上昇2010
- Author(s)
  高橋真美、石ヶ守里加子、堀美香、小宮雅美、武藤倫弘、杉村隆、若林敬二
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22590371
[Presentation] ハムスター膵管発がんにおけるオステオポンチンとそのスプライシングバリアントの発現上昇2010
- Author(s)
  高橋真美
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22590371
[Presentation] 大腸及び膵臓発がんの抑制機構。2006
- Author(s)
  高橋真美, et. al.
- Organizer
  第13回日本がん予防学会
- Place of Presentation
  京都
- Year and Date
  2006-07-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590390
[Presentation] Inhibition mechanisms of colorectal and pancrestic carcinogenesis2006
- Author(s)
  Takahashi, M., et. al.
- Organizer
  The 13th Annual Meeting of Japanese Association for Cancer Prevention
- Place of Presentation
  kyoto
- Year and Date
  2006-07-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590390
[Presentation] Concomitant suppression by pioglitazone of hyperlipidemia and N-nitrosobis (2-oxopropyl) amine-induced pancreatic carcinogenesis hamsters.2006
- Author(s)
  Takahashi, M., et. al.
- Organizer
  Prancreatic Cancer 2006
- Place of Presentation
  Chapel Hill, NC, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590390
[Presentation] Concomitant suppression by pioglitazone of hyperlipidemia and N-nitros obis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters.2006
- Author(s)
  Takahashi, M, et. al.
- Organizer
  Pancreatic Cancer 2006
- Place of Presentation
  Chapel Hill, NC, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590390
[Presentation] Ayアレルによる膵臓発がん及び大腸発がんの促進におけるマクロファージコロニー刺激因子の関与
- Author(s)
  高橋真美、石ヶ守里加子、中西るり、尾沼若奈、小宮雅美、藤井元、武藤倫弘、田中卓二、今井俊夫
- Organizer
  第24回日本消化器癌発生学会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-25290049
[Presentation] マウス膵臓発がんにおけるAyアレルによる発がん促進
- Author(s)
  高橋真美、石ヶ守里加子、武藤倫弘、田中卓二、今井俊夫
- Organizer
  第28回発癌病理研究会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-25290049
[Presentation] Ayアレルによるマウス膵臓発がん促進におけるM-CSFの関与
- Author(s)
  高橋真美、石ヶ守里加子、尾沼若奈、小宮雅美、藤井元、武藤倫弘、田中卓二、今井俊夫
- Organizer
  第72回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25290049
[Presentation] 膵臓特異的K-ras変異体発現マウスと肥満モデルAyマウスとの交配による膵臓発がん促進
- Author(s)
  高橋真美
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌市教育文化会館（札幌）
- Data Source
  KAKENHI-PROJECT-22590371
[Presentation] 膵臓特異的K-ras変異体発現マウスの膵臓発がん過程におけるオステオポンチンの作用
- Author(s)
  高橋真美
- Organizer
  第19回日本がん予防学会
- Place of Presentation
  じゅうろくプラザ（岐阜）
- Data Source
  KAKENHI-PROJECT-22590371
[Presentation] アゾキシメタン誘発大腸発がん高感受性のII型糖尿病モデルマウスにおけるAyアレルによる腫瘍形成促進
- Author(s)
  高橋真美、伊藤久美子、石ヶ守里加子、中西るり、武藤倫弘、藤井元、太田敏博、今井俊夫
- Organizer
  第20回日本がん予防学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25290049

1. MUTOH Michihiro (30392335)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. TERASAKI Masaru (10391195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 福田一典 (80156778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 小島弘幸 (10414286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 泉谷昌志 (90532739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 筆宝義隆 (30359632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 藤井元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 桑田健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAHASHI Mami 高橋 真美

高橋 真美 タカハシ マミ

Research Projects

Research Products

Co-Researchers

Establishment and analysis of human pancreatic acinar cell carcinoma cell lines to elucidate the pathogenesis of rare cancers and to explore new treatment methods.

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Elucidation of molecular network-regulating mechanisms on pancreatic tumor microenvironment suppression by fucoxanthin

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Involvement of melanocortin type 1 receptor dysfunction in pancreatic carcinogenesisPrincipal Investigator

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Analysis of the effects of the host environment factors on pancreatic cancer malignancy at whole body levelsPrincipal Investigator

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Involvement of the melanocortin receptor pathway in pancreatic and colorectal carcinogenesis and its application to cancer preventionPrincipal Investigator

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Analysis of physical roles of osteopontin and its cancer-specific molecules in colorectal and pancreatic carcinogenesisPrincipal Investigator

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Promotive effects of hyperlipidemia on pancreatic ductal carcinogenesis and the mechanismsPrincipal Investigator

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Relationship between the mechanism for hyperlipidemia and intestinal polyp formation in Apc knockout micePrincipal Investigator

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Relationship between activation of beta-catenin pathway and expression of inflamatory enzymes in colon carcinogenesis in experimental animalsPrincipal Investigator

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大腸発癌におけるシクロオキシゲナーゼの関与とそのメカニズムの研究

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[Book] V―11. 国立がん研究センター国立がん研究センター研究所FIOCでの上皮性腫瘍PDXモデルの樹立例。「患者由来がんモデルを用いたがん研究実践ガイド」編集/佐々木博己。2019

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[Journal Article] Characterization of the large‐scale Japanese patient‐derived xenograft (J‐PDX) library2021

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[Journal Article] Effect of fucoxanthinol on pancreatic ductal adenocarcinoma cells from an N-nitrosobis(2-oxopropyl)amine-initiated Syrian golden hamster pancreatic carcinogenesis model.2021

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[Journal Article] Fucoxanthin Prevents Pancreatic Tumorigenesis in C57BL/6J Mice That Received Allogenic and Orthotopic Transplants of Cancer Cells2021

Author(s)

TAKAHASHI Mami 高橋真美

高橋真美タカハシマミ

[Journal Article] A fucoxanthinol induces apoptosis in a pancreatic 　intraepithelial neoplasia cells.2021